Displaying drugs 3751 - 3775 of 11299 in total
Velpatasvir
Velpatasvir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … Velpatasvir acts as a defective substrate for NS5A (Non-Structural Protein 5A), a non-enzymatic viral ... Velpatasvir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 …
Indoramin
Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression action.
Approved
Withdrawn
Matched Description: … Indoramin is a discontinued piperidine antiadrenergic drug with the trade names Baratol and Doralese. ... It is a selective alpha-1 adrenergic antagonist with no reflex tachycardia and direct myocardial depression …
Haemophilus influenzae type B strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen
Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is a vaccine for intramuscular injection used in the prevention of invasive disease caused by Haemophilus influenzae type b. H. influenzae is a Gram-negative coccobacillus that can cause infections including sepsis and meningitis. The vaccine contains the Haemophilus...
Approved
Investigational
Matched Description: … Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen is a ... *H. influenzae* is a Gram-negative coccobacillus that can cause infections including sepsis and meningitis ... contains the *Haemophilus influenzae* type b capsular polysaccharide (polyribosyl-ribitol-phosphate, PRP), a …
Influenza B virus B/Utah/9/2014 hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Influenza B virus B/Iowa/06/2017 hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Influenza B virus B/Singapore/WUH4618/2021 antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Fecal microbiota
Fecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an FDA-approved option to prevent the recurrence of Clostridioides difficile infection (CDI) in patients given an antibacterial treatment for recurrent CDI.[A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases...
Approved
Investigational
Matched Description: … Recurrent CDI has a high risk of mortality and a high failure rate. ... Fecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an ... cases requiring hospitalization has been lower over the years, the recurrence of CDI still represents a …
Cryptenamine
Cryptenamine is a mixture of closely related hypotensive alkaloids from Veratrum album (Liliaceae). It has been used in the treatment of hypertension but has largely been replaced by drugs with fewer adverse effects. Cryptenamine has a marked and re-producible depressor effect when given intravenously to hypertensive patients, however the mechanism...
Approved
Matched Description: … Cryptenamine is a mixture of closely related hypotensive alkaloids from Veratrum album (Liliaceae). ... Cryptenamine has a marked and re-producible depressor effect when given intravenously to hypertensive …
Spirapril
Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration. ACE inhibitors are used primarily in treatment of hypertension and congestive heart failure.
Approved
Sulfacytine
Sulfacytine is a short-acting sulfonamide. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism...
Approved
Matched Description: … Sulfacytine is a short-acting sulfonamide. ... Sulfacytine is a competitive inhibitor of the enzyme dihydropteroate synthetase. ... The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive …
Methylnaltrexone
Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Matched Description: … It is also a weak CYP2D6 inhibitor. FDA approved in 2008. ... Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract …
Phenylethyl resorcinol
A tyrosinase inhibitor with skin-lightening activity.
Approved
Experimental
Matched Description: … A tyrosinase inhibitor with skin-lightening activity. …
Nesiritide
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
Approved
Investigational
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. ... Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea …
Keyhole limpet hemocyanin
Keyhole limpet hemocyanin is an immune modulator, given as a vaccine to help the body respond to cancer. A natural protein isolated from the marine mollusc keyhole limpet. Keyhole limpet hemocyanin is an immunogenic carrier protein that, in vivo, increases antigenic immune responses to haptens and other weak antigens such...
Approved
Investigational
Matched Description: … A natural protein isolated from the marine mollusc keyhole limpet. ... Keyhole limpet hemocyanin is an immune modulator, given as a vaccine to help the body respond to cancer …
Troleandomycin
A macrolide antibiotic that is similar to erythromycin.
Approved
Matched Description: … A macrolide antibiotic that is similar to erythromycin. …
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Description: … Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a …
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Description: … Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a …
Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 8 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Description: … Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a ... capsular antigens of *Streptococcus pneumoniae* serotype 8 individually conjugated to the CRM197 protein, a …
Diethylstilbestrol
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)
The FDA withdrew its...
Approved
Investigational
Withdrawn
Matched Description: … It was also used formerly as a growth promoter in animals. ... A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. ... to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a …
Imdevimab
Imdevimab is a monoclonal antibody combined with casirivimab in Regeneron's antibody cocktail known as REGEN-COV2 for the treatment of COVID-19. This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. These antibodies have been formulated to...
Approved
Experimental
Matched Description: … Imdevimab is a monoclonal antibody combined with [casirivimab] in Regeneron's antibody cocktail known ... [L23539] This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition …
Rifampicin
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts...
Approved
Matched Description: … A semisynthetic antibiotic produced from Streptomyces mediterranei. ... It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. ... In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex …
Neostigmine
A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.
Approved
Vet approved
Matched Description: … A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle …
Unoprostone
Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate.
The main indication of Unoprostane is treatment of glucoma.
Approved
Investigational
Matched Description: … Unoprostone isopropyl is a prostaglandin analogue. ... Ophthalmic Solution 0.15% is a synthetic docosanoid. …
Darvadstrocel
Darvadstrocel is a suspension of expanded human allogeneic adipose-derived mesenchymal stem cells extracted from the subdermal adipose tissue of healthy donors via liposuction. Darvadstrocel was first approved by the European Commission on March 23, 2018, under the brand name Alofisel. It is indicated for the treatment of complex perianal fistulas...
Approved
Experimental
Matched Description: … Darvadstrocel is a suspension of expanded human allogeneic adipose-derived mesenchymal stem cells extracted ... Perianal fistula is a common manifestation of Crohn’s disease and is often difficult to manage, as it …
Metergoline
Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors. Metergoline is an antagonist at various 5-HT receptor subtypes at a relatively low concentration and agonist at dopamine receptors. Its use has been studied in various clinical settings such as a treatment for seasonal...
Approved
Matched Description: … Metergoline is an antagonist at various 5-HT receptor subtypes at a relatively low concentration and ... Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors ... [A27181] Its use has been studied in various clinical settings such as a treatment for seasonal affective …
Displaying drugs 3751 - 3775 of 11299 in total