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Displaying drugs 401 - 425 of 11571 in total

Azelaic acid

Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is also produced by Malassezia furfur, also known as Pityrosporum ovale, which is a species of fungus that is normally found on human skin. Azelaic acid is effective against a number of skin conditions, such...
Approved
Matched Description: … topically in a cream formulation of 20%. ... Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. ... It is also produced by _Malassezia furfur_, also known as _Pityrosporum ovale_, which is a species of …

Thimerosal

Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Matched Description: … This compound is a well-established and widely used antiseptic and antifungal agent. ... Although thimerosal is banned in several countries, it continues to be included as a preservative in ... Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Hydroquinone

Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … As a result of these concerns, hydroquinone has been banned in the EU and UK. ... Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Sermorelin

Sermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide (GRF 1-29 NH 2 ) that corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone (GHRH or GRF) consisting of 44 amino acid residues
Approved
Withdrawn

Ziconotide

Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail Conus magus comprising 25 amino acids with three disulphide bonds.[A202835, L13389] Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because...
Approved
Matched Description: … Ziconotide (also known as SNX-111) is a neurotoxic peptide derived from the cone snail _Conus magus_ …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Etrasimod

Etrasimod is a synthetic next-generation selective Sphingosine 1-phosphate (S1P) receptor modulator that targets the S1P1,4,5 with no detectable activity on S1P2 and S1P3 receptors. S1P receptors are membrane-derived lysophospholipid signaling molecules that are involved in the sequestration of circulating peripheral lymphocytes in lymph nodes. Therefore, S1P receptor modulators like etrasimod...
Approved
Matched Description: … Etrasimod is a synthetic next-generation selective Sphingosine 1-phosphate (S1P) receptor modulator that ... like etrasimod were investigated in treating immune-mediated diseases like ulcerative colitis where a ... consisting of the Elevate UC 52 and Elevate UC 12 clinical trials, that investigates the efficacy of a …

Propranolol

Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Description: … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times ... [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …

Gabapentin

Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Description: … Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA ... A14097,A186179] Gabapentin has some stark advantages as compared with other anti-epileptics, such as a ... [L8717] It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures …
Matched Products: … GABAPENTIN HEXAL A/S …

Iopanoic acid

Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography.
Approved
Withdrawn
Matched Description: … Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Fludeoxyglucose (18F)

Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is administered by intravenous injection.
Approved
Investigational
Matched Description: … Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Tuberculin purified protein derivative

Tuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. The diagnostic test is commonly referred to as the Mantoux test which serves to minimize the risk of transmission of infection with Mycobacterium tuberculosis...
Approved
Matched Description: … Tuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction ... The purified protein fraction is isolated from culture media filtrates of a human strain of Mycobacterium …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Testosterone cypionate

Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and longer half-life. It was developed by the company Pharmacia and Upjohn and FDA approved on July 25,...
Approved
Matched Iupac: … 9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta …

Mebendazole

A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …

Pramlintide

Pramlintide is a relatively new adjunct treatment for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals. It is derived from amylin, a hormone that is released into the bloodstream, in a similar pattern as insulin, after a meal. Like insulin, amylin is deficient in individuals with diabetes.
Approved
Investigational
Matched Description: … , after a meal. ... It is derived from amylin, a hormone that is released into the bloodstream, in a similar pattern as insulin ... Pramlintide is a relatively new adjunct treatment for diabetes (both type 1 and 2), developed by Amylin …

Menadione

A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Approved
Nutraceutical
Matched Description: … A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted …

Asfotase alfa

Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP). Hypophosphatasia is almost always fatal when severe skeletal disease is obvious at birth. By replacing deficient ALP, treatment with Asfotase Alfa aims to improve the elevated enzyme substrate levels...
Approved
Investigational
Matched Description: … Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying …

Fluoxymesterone

An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Iupac: … 9b-fluoro-1,10-dihydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …

Lindane

An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports...
Approved
Withdrawn
Matched Description: … An organochlorine insecticide that has been used as a pediculicide and a scabicide. ... , and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical ... In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Nitrous acid

Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. There is also research to investigate...
Approved
Investigational
Matched Description: … needed in a basic health system. ... It is on the World Health Organization's List of Essential Medicines, a list of the most important medications …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Atorvastatin

Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Description: … Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. ... More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A ... heterocyclic core unit and a 3,5-dihydroxypentanoyl side chain identical to its parent compound. …
Matched Mixtures name: … TIAZOMET ® A 40/10 TABLETAS …

Coenzyme M

Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Description: … Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ademetionine

Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Approved
Investigational
Nutraceutical

Quetiapine

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high...
Approved
Matched Description: … Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used ... [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects ... It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such …
Matched Products: … QUETIAPINA SANDOZ A/S …

Teriparatide

Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... in November 2002 and in Europe in April 2003,[A251400] teriparatide makes the first approved drug in a …

Avatrombopag

Avatrombopag (Doptelet), is an orally administered, small molecule thrombopoietin receptor (c-Mpl) agonist that increases platelet number without increasing platelet activation,[A33097,L2824] thereby decreasing the need for blood transfusions. Patients with thrombocytopenia and chronic liver disease often require platelet transfusions before surgical procedures to decrease the risk of bleeding. Thrombocytopenia is a...
Approved
Investigational
Matched Description: … occurring as a result of liver disease or a consequence of interferon-based antiviral therapy. ... large population of patients to avoid a platelet transfusion before a procedure by increasing platelet ... [A33095] Thrombocytopenia is a common complication in patients suffering from chronic liver disease, …
Displaying drugs 401 - 425 of 11571 in total