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Displaying drugs 401 - 425 of 11559 in total

Fludeoxyglucose (18F)

Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is administered by intravenous injection.
Approved
Investigational
Matched Description: … Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Bronopol

Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial properties. First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives . Bronopol is used as a microbicide or microbiostat...
Approved
Matched Description: … First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was ... Bronopol is used as a microbicide or microbiostat in various commercial and industrial applications, ... The agent is largely available commercially as an antibacterial for a variety of industrial purposes …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Tuberculin purified protein derivative

Tuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. The diagnostic test is commonly referred to as the Mantoux test which serves to minimize the risk of transmission of infection with Mycobacterium tuberculosis...
Approved
Matched Description: … Tuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction ... The purified protein fraction is isolated from culture media filtrates of a human strain of Mycobacterium …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Testosterone cypionate

Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and longer half-life. It was developed by the company Pharmacia and Upjohn and FDA approved on July 25,...
Approved
Matched Iupac: … 9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta …

Mebendazole

A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …

Pramlintide

Pramlintide is a relatively new adjunct treatment for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals. It is derived from amylin, a hormone that is released into the bloodstream, in a similar pattern as insulin, after a meal. Like insulin, amylin is deficient in individuals with diabetes.
Approved
Investigational
Matched Description: … , after a meal. ... It is derived from amylin, a hormone that is released into the bloodstream, in a similar pattern as insulin ... Pramlintide is a relatively new adjunct treatment for diabetes (both type 1 and 2), developed by Amylin …

Linaclotide

Linaclotide is a synthetic 14-amino acid cyclic peptide and first-in-class guanylate cyclase-C (G-CC) agonist.[A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C. It is also a homolog of a heat-stable enterotoxin derived from Escherichia coli, the first natural ligand...
Approved
Matched Description: … [A260276] It is also a homolog of a heat-stable enterotoxin derived from _Escherichia coli_, the first ... Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C …

Menadione

A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Approved
Nutraceutical
Matched Description: … A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted …

Asfotase alfa

Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP). Hypophosphatasia is almost always fatal when severe skeletal disease is obvious at birth. By replacing deficient ALP, treatment with Asfotase Alfa aims to improve the elevated enzyme substrate levels...
Approved
Investigational
Matched Description: … Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying …

Fluoxymesterone

An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Iupac: … 9b-fluoro-1,10-dihydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …

Lindane

An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports...
Approved
Withdrawn
Matched Description: … An organochlorine insecticide that has been used as a pediculicide and a scabicide. ... , and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical ... In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Nitrous acid

Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. There is also research to investigate...
Approved
Investigational
Matched Description: … needed in a basic health system. ... It is on the World Health Organization's List of Essential Medicines, a list of the most important medications …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Atorvastatin

Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Description: … Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. ... More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A ... heterocyclic core unit and a 3,5-dihydroxypentanoyl side chain identical to its parent compound. …
Matched Mixtures name: … TIAZOMET ® A 40/10 TABLETAS …

Coenzyme M

Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Description: … Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ademetionine

Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Approved
Investigational
Nutraceutical

Quetiapine

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high...
Approved
Matched Description: … Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used ... [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects ... It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such …
Matched Products: … QUETIAPINA SANDOZ A/S …

Teriparatide

Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... in November 2002 and in Europe in April 2003,[A251400] teriparatide makes the first approved drug in a …

Avatrombopag

Avatrombopag (Doptelet), is an orally administered, small molecule thrombopoietin receptor (c-Mpl) agonist that increases platelet number without increasing platelet activation,[A33097,L2824] thereby decreasing the need for blood transfusions. Patients with thrombocytopenia and chronic liver disease often require platelet transfusions before surgical procedures to decrease the risk of bleeding. Thrombocytopenia is a...
Approved
Investigational
Matched Description: … occurring as a result of liver disease or a consequence of interferon-based antiviral therapy. ... large population of patients to avoid a platelet transfusion before a procedure by increasing platelet ... [A33095] Thrombocytopenia is a common complication in patients suffering from chronic liver disease, …

Alimemazine

A phenothiazine derivative that is used as an antipruritic.
Approved
Vet approved
Matched Description: … A phenothiazine derivative that is used as an antipruritic. …

Phleum pratense pollen

Phleum pratense pollen allergenic extract is used in allergenic testing.
Approved
Investigational
Matched Mixtures name: … SLITone ULTRA D. glomerata/ L. perenne/ P. pratense/ P. pratensis/ A. odoratum …

Quinapril

Quinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat.[L8420,L8423] It is used to treat hypertension and heart failure.[L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. Quinapril was granted FDA approval...
Approved
Investigational
Matched Description: … [L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999. ... [L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension …

Clomipramine

Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals,...
Approved
Investigational
Vet approved
Matched Description: … See toxicity section below for a complete listing of side effects. ... In depressed individuals, clomipramine exerts a positive effect on mood. ... They contain a tricyclic ring system with an alkyl amine substituent on the central ring. …
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Retapamulin

Retapamulin, marketed by GlaxoSmithKline as the ointment Altabax, is an antibiotic for skin infections like impetigo. It was approved by the FDA in April 2007.
Approved

Pipecuronium

Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking agent.
Approved
Matched Iupac: … 1,7-bis(acetyloxy)-8-(4,4-dimethylpiperazin-4-ium-1-yl)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking …

Desoxycorticosterone acetate

Approved
Matched Iupac: … 9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Displaying drugs 401 - 425 of 11559 in total