Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 426 - 450 of 15295 in total

Aluminum chlorohydrate

Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Iupac: … dialuminium(3+) ion hydrate chloride pentahydroxide …
Matched Description: … It is also used as a coagulant in the water purification process. ... Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl( ... It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. …
Matched Mixtures name: … PERS-MANT %19 + %2 JEL (30 G) …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … Spai-sons Floop C ... Antiperspirant Roll On 22% ... Antiperspirant Dry 2 oz Men …

Bumetanide

Bumetanide is a sulfamyl diuretic.
Approved
Matched Synonyms: … 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Description: … Bumetanide is a sulfamyl diuretic. …
Matched Products: … Burinex 2 mg - Ampullen …

Ximelagatran

Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin- ... 1-yl]- 2-oxo-ethyl]amino]acetate …
Matched Iupac: … ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin ... -1-yl]-2-oxoethyl]amino}acetate …
Matched Description: … Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary ... In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after ... reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries …

Ferric carboxymaltose

Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Ferinject Solution for Injection 50mg/ml ... Ferinject® 50 mg iron/mL solution for injection/infusion …

Lenvatinib

Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib also inhibits other RTKs that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular...
Approved
Investigational
Matched Synonyms: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Iupac: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Description: … factor (FGF) receptors FGFR1, 2, 3, and 4; the platelet derived growth factor receptor alpha (PDGFRα) ... is poor, leading to a push for the development of more targeted therapies such as lenvatinib. ... These receptor tyrosine kinases (RTKs) located in the cell membrane play a central role in the activation …
Matched Salts cas: … 857890-39-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Testosterone enantate benzilic acid hydrazone

Approved
Experimental
Matched Synonyms: … Testosterone 17-enanthate 3-benzilic acid hydrazone …
Matched Iupac: … ,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl heptanoate ... (1S,3aS,3bR,9aR,9bS,11aS)-7-[(2-hydroxy-2,2-diphenylacetamido)imino]-9a,11a-dimethyl-1H,2H,3H,3aH,3bH …

Influenza B virus B/Victoria/705/2018 BVR-11 antigen (formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. …
Matched Mixtures name: … FLUAD Injektionssuspension in einer Fertigspritze ... Sandovac Injektionssuspension in einer Fertigspritze …

Melopsittacus undulatus feather

Melopsittacus undulatus feather is used in allergenic testing.
Approved
Matched Description: … Melopsittacus undulatus feather is used in allergenic testing. …

Trastuzumab deruxtecan

Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers. It is classified as an antibody-drug conjugate. The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from other members of...
Approved
Investigational
Matched Description: … for use in certain types of treatment-resistant HER2-positive cancers. ... Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved ... and was first approved by the FDA in 2019. …
Matched Categories: … MATE 2 Substrates ... HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors …
Matched Products: … ENHERTU POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIAL …

Methylprednisolone hemisuccinate

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Iupac: … ,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}-4-oxobutanoic acid ... 4-{2-[(1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-5,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H …
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Salts cas: … 2375-03-3 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … A-methapred ... MEDASON FOR INJECTION ... SOLU-PRED FOR INJECTION 500mg/vial …

Gastric intrinsic factor

Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later on in the small intestine. When vitamin B12 is provided in combination with intrinsic factor, intrinsic factor reduces...
Approved
Experimental
Matched Description: … Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the ... parietal cells of the stomach that is necessary for the absorption of vitamin B12 (cobalamin) later ... (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid for the treatment of anemias responsive …

Vibrio cholerae Inaba 6973 El Tor biotype, formalin inactivated

Approved

Methotrexate

Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Iupac: … (2S)-2-[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic …
Matched Description: … Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis ... effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in ... [A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … ZEXATE 15 MG/3 ML ENJEKTABL SOLUSYON FLAKON, 1 ADET ... TREXOL - Methotrexate Solution for Injection 25 mg/ml ... METOTREXATO 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …

Cinnarizine

First synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner...
Approved
Investigational
Matched Synonyms: … 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine …
Matched Iupac: … 1-(diphenylmethyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Description: … for the control of vestibular disorders and motion sickness. ... calcium channel blockage), which happen mostly in brain. ... Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system …
Matched Salts cas: … 25332-14-3 …

Tenofovir alafenamide

Tenofovir alafenamide is a novel tenofovir prodrug developed in order to improve renal safety when compared to the counterpart tenofovir disoproxil. Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal...
Approved
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl] …
Matched Description: … [T239] Tenofovir alafenamide is an alanine ester form characterized for presenting low systemic levels ... Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when ... of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Heterocyclic Compounds, 2-Ring ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use …

Channel catfish

Channel catfish allergenic extract is used in allergenic testing.
Approved
Matched Description: … Channel catfish allergenic extract is used in allergenic testing. …

Carboxymethylcellulose

Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or thickener and emulsifier. It is also one of the most common viscous polymers used in...
Approved
Investigational
Matched Description: … It is added in food products as a viscosity modifier or thickener and emulsifier. ... Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose ... in the treatment of aqueous tear-deficient dry eye symptoms and ocular surface staining [A33029]. …
Matched Mixtures name: … Clear Eyes for Dry Eyes ... REFRESH Optive Mega-3 ... REFRESH Optive Mega-3 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Cho-A Derm ... Cho-A Derm-R ... Cho-A Derm Beauty Care …

Trimethobenzamide

Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric...
Approved
Investigational
Matched Synonyms: … N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamide …
Matched Iupac: … N-({4-[2-(dimethylamino)ethoxy]phenyl}methyl)-3,4,5-trimethoxybenzamide …
Matched Description: … Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. ... In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while …
Matched Categories: … Antihistamines for Systemic Use …
Matched Products: … VOMET 2 ML 200 MG 6 AMPUL ... VOSELMIT 200 MG 2 ML 6 AMPUL ... EMEDUR 200 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 50 ADET …

Coagulation factor X human

Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Description: … However its use is limited in the perioperative setting for the management of bleeding in major surgery ... Coagulation Factor X (Human) solution is approved by the FDA for intravenous injection under the market ... Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and …
Matched Mixtures name: … PROTROMPLEX TIM 3 ... PROTROMPLEX TIM 3 ... BERIPLEX P/N 500 POWDER FOR SOLUTION FOR INJECTION …

Abacavir

Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
Approved
Investigational
Matched Synonyms: … {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol …
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol …
Matched Description: … In vivo, abacavir sulfate dissociates to its free base, abacavir. ... Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV ... Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration …
Matched Salts cas: … 188062-50-2 …
Matched Mixtures name: … N/A ... ABACAVIR E LAMIVUDINA LUPIN ... ABACAVIR E LAMIVUDINA LUPIN …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Heterocyclic Compounds, 2-Ring ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use …

Somatrogon

Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Description: … Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting ... It is a chimeric product generated by fusing three copies of the C-terminal peptide (CTP), or 28 carboxy-terminal ... [L39060] In June 2023, the FDA approved the use of somatrogon also for the treatment of pediatric growth …

Rifabutin

A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Approved
Investigational
Matched Synonyms: … 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV ... 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S …
Matched Iupac: … 12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2- …
Matched Description: … complex infection in HIV-positive patients. ... A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium …
Matched Categories: … Antiinfectives for Systemic Use ... Drugs for Acid Related Disorders ... Drugs for Treatment of Tuberculosis ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …

Efanesoctocog alfa

Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Description: … VIII therapy for hemophilia A. ... Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the ... [L45379] The use of FVIII replacement products is beneficial in patients with hemophilia A; however, …

Ferrous cysteine glycinate

Approved
Matched Synonyms: … Ferrous cysteine glycinate chelate (1:2:1) …
Matched Iupac: … lambda2-iron(2+) (2R)-2-amino-3-sulfanylpropanoic acid 2-aminoacetic acid (2R)-2-amino-3-sulfanidylpropanoate …

Desflurane

Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane.[A226390,A39015,A226893]. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted...
Approved
Matched Synonyms: … 1,1,1,2-tetrafluoro-2-(difluoromethoxy)ethane ... (±)-2-difluoromethyl 1,2,2,2-tetrafluoroethyl ether …
Matched Iupac: … 2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane …
Matched Description: … It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled ... Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than …
Displaying drugs 426 - 450 of 15295 in total