Displaying drugs 626 - 650 of 11304 in total
Glycolic acid
Approved
Investigational
Albumin human
Human serum albumin is the primary protein present in human blood plasma. The main function of albumin is to maintain the oncotic pressure of blood . It binds to water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates). Albumin represents approximately...
Approved
Matched Description: … Human albumin is a small globular protein (molecular weight: 66.5 kDa), consisting of a single chain ... This is a biosimilar drug to existing human serum albumin and was approved for a biological license at ... Each domain comprises two separate sub-domains (A and B) [A40060]. …
Sulfamerazine
A sulfanilamide that is used as an antibacterial agent.
Approved
Vet approved
Matched Description: … A sulfanilamide that is used as an antibacterial agent. …
Oxidronic acid
Approved
Copper oxodotreotide Cu-64
Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over 68Ga-labeled somatostatin analogs for positron emission tomography (PET). Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several times a day, and lower positron...
Approved
Matched Description: … [A220348] Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several ... times a day, and lower positron energy lending to improved spatial resolution. ... Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over …
Hyoscyamine
Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Matched Description: … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. ... [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic …
Dipivefrin
Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Approved
Matched Description: … Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. …
Metamizole
Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to...
Approved
Investigational
Withdrawn
Matched Description: … Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. ... It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. …
Tebentafusp
Tebentafusp is a gp100 peptide-HLA-directed CD3 T cell engager. It is a bispecific, fusion protein and first-in-class drug of immune-mobilizing monoclonal T cell receptors against cancer (ImmTACs), a recently developed cancer immunotherapy with a novel mechanism of action. ImmTACs bind to target cancer cells that express a specific antigen of...
Approved
Investigational
Matched Description: … cell receptors against cancer (ImmTACs), a recently developed cancer immunotherapy with a novel mechanism ... Tebentafusp is a gp100 peptide-HLA-directed CD3 T cell engager. ... [L39995] It is a bispecific, fusion protein and first-in-class drug of immune-mobilizing monoclonal T …
Tralokinumab
Atopic dermatitis (AD) is an inflammatory skin disorder that causes skin inflammation, skin barrier dysfunction, and chronic pruritus. It is estimated to affect up to 20% of adults and children worldwide, and is frequently associated with other atopic conditions such as asthma or allergic rhinitis. While AD is a heterogenous...
Approved
Investigational
Matched Description: … While AD is a heterogenous condition with a variety of apparent genetic and environmental causes,[A242422 ... [A242427]
Tralokinumab is a fully human IgG4 monoclonal antibody targeted against IL-13. …
Gepirone
Gepirone, an azapirone, is a pharmacologic analog of buspirone that acts selectively on the pre- and post-synaptic 5HT1A receptors. Although earlier clinical trials showed promising results for gepirone, its formulation as an immediate-release tablet necessitates frequent administration due to the short half-lives. It was not until an extended-release formulation of...
Approved
Investigational
Matched Description: … potential candidate for a new antidepressant. ... Gepirone, an azapirone, is a pharmacologic analog of [buspirone] that acts selectively on the pre- and ... It was not until an extended-release formulation of gepirone was made available that gepirone became a …
Letermovir
Letermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors. Letermovir has recieved both priority and orphan drug status...
Approved
Investigational
Matched Description: … [L1021] It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors …
Thiamylal
A barbiturate that is administered intravenously for the production of complete anesthesia of short duration, for the induction of general anesthesia, or for inducing a hypnotic state. (From Martindale, The Extra Pharmacopoeia, 30th ed, p919)
Approved
Vet approved
Matched Description: … , for the induction of general anesthesia, or for inducing a hypnotic state. ... A barbiturate that is administered intravenously for the production of complete anesthesia of short duration …
Ribavirin
Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Description: … Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Ribavirin is a prodrug that is metabolized into nucleoside analogs that blocks viral RNA synthesis and …
Guanethidine
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. [PubChem]
Approved
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Description: … Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme ... Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy …
Olipudase alfa
Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Description: … [L42740] ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a …
Zinc ascorbate
Approved
Nutraceutical
Elagolix
Elagolix has been used in trials studying the basic science and treatment of Endometriosis, Folliculogenesis, Uterine Fibroids, Heavy Uterine Bleeding, and Heavy Menstrual Bleeding. As of 24 July 2018, however, the U.S. Food and Drug Administration (FDA) approved AbbVie's elagolix under the brand name Orilissa as the first and only...
Approved
Investigational
Matched Description: … this condition can suffer for up to six to ten years and visit multiple physicians before receiving a …
Olmesartan
Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Description: … ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing ... ARBs such as olmesartan have been shown in a number of large-scale clinical outcomes trials to improve ... blockade of RAAS via AT1 receptor blockade inhibits negative regulatory feedback within RAAS, which is a …
Matched Mixtures name: … OLMEDOXTAN A® ... OLMETAN A 20/5 TABLETAS RECUBIERTAS ... OLMETAN® A 40/5 TABLETAS RECUBIERTAS …
Matched Mixtures name: … OLMEDOXTAN A® ... OLMETAN A 20/5 TABLETAS RECUBIERTAS ... OLMETAN® A 40/5 TABLETAS RECUBIERTAS …
Cyclothiazide
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Description: … As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the …
Dantron
Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.
Approved
Investigational
Withdrawn
Micafungin
Micafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Approved
Investigational
Displaying drugs 626 - 650 of 11304 in total