Displaying drugs 676 - 700 of 11305 in total
Ustilago avenae
Ustilago avenae is a fungus which can provoke allergic reactions. Ustilago avenae extract is used in allergenic testing.
Approved
Matched Description: … Ustilago avenae is a fungus which can provoke allergic reactions. …
Rituximab
Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Description: … , has now been approved for a variety of conditions [FDA label]. ... Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the ... FDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however …
Retifanlimab
Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2). By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune response against cancer cells. Other monoclonal...
Approved
Investigational
Matched Description: … Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor ... On October 2021, Incyte Biosciences withdrew its application for a marketing authorization of retifanlimab ... [L45608,L45618] On March 2023, the FDA granted accelerated approval to retifanlimab for a different indication …
Nirmatrelvir
Nirmatrelvir (PF-07321332) is an orally bioavailable 3C-like protease (3CLPRO) inhibitor that is the subject of clinical trial NCT04756531. 3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2. Without the activity of the SARS-CoV-2 3CLPRO, nonstructural proteins (including proteases) cannot be released to perform their functions, inhibiting viral replication.[A234224,A234229,A234234]...
Approved
Investigational
Matched Description: … [L33359]
In December 2021, the FDA granted an emergency use authorization to Paxlovid, a co-packaged …
Gefitinib
Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Description: … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. ... Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant …
Obinutuzumab
Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is a black box warning of fatal Hepatitis B Virus (HBV)...
Approved
Investigational
Matched Description: … Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to ... There is a black box warning of fatal Hepatitis B Virus (HBV) reactivation and fatal Progressive Multifocal …
Brompheniramine
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Mixtures name: … Altidec A …
Edoxudine
Edoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. The obtained product is an antiviral ointment. The activity of edoxudine against herpes simplex virus was first recognized in 1967. It was later recognized...
Approved
Investigational
Withdrawn
Matched Description: … Edoxudine is a deoxythymidine analog with activity against herpes simplex virus. ... It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. ... It was later recognized to be effective in vivo in a preclinical model of keratitis caused by herpes …
Lisinopril
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Description: … [A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Edetate calcium disodium anhydrous
Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Niacinamide ascorbate
Approved
Nutraceutical
Bexarotene
Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Approved
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Flibanserin
Flibanserin is the first drug to be approved for hypoactive sexual desire disorder (HSDD) in premenopausal women by the FDA in August 2015. It was originally developed as an antidepressant medication by Boehringer Ingelheim, but showed lack of efficacy in trials and was further developed as a hypoactive sexual disorder...
Approved
Investigational
Matched Description: … medication by Boehringer Ingelheim, but showed lack of efficacy in trials and was further developed as a …
Perampanel
Perampanel is a noncompetitive AMPA glutamate receptor antagonist. It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. The FDA label includes an important black-boxed warning...
Approved
Matched Description: … Perampanel is a noncompetitive AMPA glutamate receptor antagonist. …
Alnus serrulata pollen
Alnus serrulata pollen allergenic extract is used in allergenic testing.
Approved
Aurothioglucose
Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis.
Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis . The use of gold compounds has decreased since the 1980s...
Approved
Withdrawn
Candida albicans
Candida albicans is a fungus which can provoke allergic reactions. Candida albicans is used in allergenic testing.
Approved
Matched Description: … Candida albicans is a fungus which can provoke allergic reactions. …
Morus alba pollen
Morus alba pollen is the pollen of the Morus alba plant. Morus alba pollen is mainly used in allergenic testing.
Approved
Cromoglicic acid
A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Approved
Matched Description: … A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells …
Sodium glycerophosphate
Sodium glycerophosphate is one of several glycerophosphate salts. It is used clinically to treat or prevent low phosphate levels [FDA Label]. Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body . The extent of this reaction is dependent on the activity of serum alkaline phosphatases.
Approved
Bromazepam
One of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.
Approved
Illicit
Investigational
Matched Description: … It is a intermediate-acting benzodiazepine. ... It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. …
Brivaracetam
Brivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam . It is available under the brand name Briviact made by UCB. Briviact received FDA approval on February 19, 2016 .
Approved
Investigational
Matched Description: … Brivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures …
Rifamycin
Rifamycin is the prime member of the rifamycin family which are represented by drugs that are a product of fermentation from the gram-positive bacterium Amycolatopsis mediterranei, also known as Streptomyces mediterranei. The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence...
Approved
Investigational
Matched Description: … status a priority review. ... Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801] ... Rifamycin is the prime member of the rifamycin family which are represented by drugs that are a product …
Fluocinolone acetonide
Fluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a corticosteroid that presents a high lipophilicity. It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices. This type of device containing fluocinolone acetonide was developed by Taro...
Approved
Investigational
Vet approved
Matched Description: … corticosteroid that presents a high lipophilicity. ... Fluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a …
Displaying drugs 676 - 700 of 11305 in total