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Displaying drugs 226 - 250 of 11299 in total

Ferric carboxymaltose

Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …

Nickel sulfate

Nickel sulfate is used in allergenic testing.
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …

Cobalt chloride

Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …

Digitoxin

A cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)
Approved
Investigational
Matched Iupac: … methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-3a-hydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … A cardiac glycoside sometimes used in place of digoxin. ... It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Compounds used in a research, industrial, or household setting ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Tedizolid phosphate

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Description: … [A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the ... vancomycin-resistant _Enterococcus faecium_, and penicillin-resistant _Streptococcus penumoniae_, represent a ... This product is currently available as both an oral tablet and as a powder for intravenous injection. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …

Astemizole

Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
Approved
Withdrawn
Matched Description: … Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy …
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …

Romidepsin

Romidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment of cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy.
Approved
Investigational
Matched Description: … Romidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …

Pyrethrum extract

Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Description: … Pyrethrin refers to a more refined extract of pyrethrum. ... Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species. …
Matched Mixtures name: … Mata Piojos A Pediculicide Low Foaming …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Sodium hydroxide

Sodium hydroxide is also known as lye or soda , or caustic soda . At room temperature, sodium hydroxide is a white crystalline odorless solid that absorbs moisture from the air. It is a synthetically manufactured substance. When dissolved in water or neutralized with acid it releases substantial amounts of...
Approved
Matched Description: … Sodium hydroxide is generally used as a solid or a diluted in a 50% solution. ... It is a synthetically manufactured substance. ... as a pH control agent and follows good manufacturing guidelines [L1967]. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Potassium hydroxide

Potassium hydroxide, also known as lye is an inorganic compound with the chemical formula KOH. Also commonly referred to as caustic potash, it is a potent base that is marketed in several forms including pellets, flakes, and powders. It is used in various chemical, industrial and manufacturing applications. Potassium hydroxide...
Approved
Matched Description: … Potassium hydroxide is used in food to adjust pH, as a stabilizer, and as a thickening agent. ... Potassium hydroxide is also a precursor to other potassium compounds. ... Also commonly referred to as _caustic potash_, it is a potent base that is marketed in several forms …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Phenprocoumon

Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Description: … Coumarin derivative that acts as a long-acting oral anticoagulant. …
Matched Categories: … Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Zanubrutinib

Zanubrutinib is a novel Bruton's tyrosine kinase (BTK) inhibitor used for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. Mantle cell lymphoma is an aggressive mature B-cell non-Hodgkin lymphoma associated with early relapse, poor clinical outcomes, and long-term survival. BTK...
Approved
Investigational
Matched Iupac: … (7S)-2-(4-phenoxyphenyl)-7-[1-(prop-2-enoyl)piperidin-4-yl]-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxamide …
Matched Description: … trial whose tumour is entirely or partially destroyed by a drug. ... Zanubrutinib is a novel Bruton's tyrosine kinase (BTK) inhibitor used for the treatment of adult patients ... [A187967] BTK is an enzyme that plays a role in oncogenic signalling pathways, promoting the survival …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Risdiplam

Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). It increases systemic SMN protein concentrations by improving the efficiency of SMN2 gene transcription. This mechanism of action is similar to its predecessor nusinersen, the biggest difference being their route of administration: nusinersen...
Approved
Investigational
Matched Iupac: … 7-{4,7-diazaspiro[2.5]octan-7-yl}-2-{2,8-dimethylimidazo[1,2-b]pyridazin-6-yl}-4H-pyrido[1,2-a]pyrimidin …
Matched Description: … to be substantially cheaper than other available SMA therapies,[L15351] risdiplam appears to provide a …

Angiotensin II

Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Description: … and affects up to one third of patients in the intensive care unit, the FDA determined that there is a ... Pharmaceutical's Giapreza (angiotensin II) Injection for Intravenouse Infusion for the indication of acting as a …

Chloroform

Chloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula of CHCl3. It is a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE and refrigerants, but the latter application is declining. Chloroform is part of...
Approved
Vet approved
Withdrawn
Matched Description: … It is a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE ... Chloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Estradiol

Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,7 …
Matched Description: … Estradiol is a naturally occurring hormone circulating endogenously in females. ... Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester ... L11497,L11500,L11503] When used for oral or IM administration, estradiol is commonly synthesized as a …

Cefazolin

A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Description: … A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial …
Matched Products: … CEFAZOLINA SÓDICA 1 G / VIAL POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …

Cysteamine

Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys. Several preparations of cysteamine exist...
Approved
Investigational
Matched Description: … Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein ... A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the ... [L15606] Cysteamine eye drops are a practical and effective option for those affected by ocular cystinosis …

Sugammadex

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intubation that patients may require...
Approved
Matched Description: … Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced ... Sugammadex provides a new treatment option to reverse the effects of those medications and possibly help …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Pyrazinamide

A pyrazine that is used therapeutically as an antitubercular agent.
Approved
Investigational
Matched Description: … A pyrazine that is used therapeutically as an antitubercular agent. …

Dimercaprol

Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during World War II. It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. In addition, it has in the past...
Approved
Matched Description: … Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during ... Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects. ... In addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Silicon dioxide

Silicon dioxide, or silica, is an oxide of silicon with the chemical formula SiO2. It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite as transparent and tasteless crystals. Inhalation of fine crystals is toxic to humans leading to respiratory toxicity. In powdered food products...
Approved
Matched Description: … Colloidal silica is also used as a wine, beer, and juice fining agent or stabilizer. ... In powdered food products and pharmaceutical tablets, silicon dioxide is added as a flow agent to absorb …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Salicylic acid

A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically …
Matched Mixtures name: … Volon A - Tinktur …
Matched Products: … Hope In A Bottle ... Dr.G A Clear Foam Cream ... CP Dr. Babor Purity Cellular Stop Blemish Fluid …

Estriol

A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is...
Approved
Investigational
Vet approved
Matched Iupac: … (1R,2R,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Description: … A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and ... Estriol is a major urinary estrogen. …

Tucatinib

Tucatinib is a kinase inhibitor drug used with trastuzumab and capecitabine in the treatment of unresectable or metastatic HER-2 positive breast cancer. It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. Tucatinib is a promising new treatment for patients with metastatic breast cancer who...
Approved
Investigational
Matched Iupac: … N6-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)-N4-(3-methyl-4-{[1,2,4]triazolo[1,5-a]pyridin-7-yloxy}phenyl …
Matched Description: … Tucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable ... [L12951] Tucatinib is a promising new treatment for patients with metastatic breast cancer who have not …
Displaying drugs 226 - 250 of 11299 in total