Displaying drugs 3626 - 3650 of 11853 in total
Acer saccharinum pollen
Acer saccharinum pollen is the pollen of the Acer saccharinum plant. Acer saccharinum pollen is mainly used in allergenic testing.
Approved
Iva angustifolia pollen
Iva angustifolia pollen is the pollen of the Iva angustifolia plant. Iva angustifolia pollen is mainly used in allergenic testing.
Approved
Efbemalenograstim alfa
Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Matched Description: … Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating ... patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a …
Istradefylline
Istradefylline, or KW6002, was developed by Kyowa Hakko Kirin in Japan for the treatment of Parkinson's disease as an adjunct to standard therapy. Unlike standard dopaminergic therapies for Parkinson's, Istradefylline targets adenosine A2A receptors in the basal ganglia. This region of the brain is highly involved in motor control. Istradefylline...
Approved
Investigational
Matched Description: … [A184067] Unlike standard dopaminergic therapies for Parkinson's, Istradefylline targets adenosine A< …
Tenofovir disoproxil
Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs). This drug is prescribed in combination with other drugs for the management of HIV infection as well as for...
Approved
Investigational
Matched Description: … Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name ... _Viread_, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase …
Pilocarpine
A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Description: … A naturally occurring alkaloid derived from the _Pilocarpus_ plants, pilocarpine is a muscarinic acetylcholine …
Glucosamine
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Description: … Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... as a medical therapy varies due to contradictory and findings with unclear clinical significance during ... Glucosamine is commonly used over the counter as a treatment for arthritic joint pain, although its acceptance …
Sulindac
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in vivo...
Approved
Investigational
Matched Description: … Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed ... Sulindac is a prodrug, derived from sulfinylindene, that is converted _in vivo_ to an active sulfide …
Tolterodine
Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Approved
Investigational
Mivacurium
Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Approved
Matched Description: … Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. ... cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a …
Tocainide
An antiarrhythmic agent which exerts a potential- and frequency-dependent block of sodium channels.
Approved
Matched Description: … An antiarrhythmic agent which exerts a potential- and frequency-dependent block of sodium channels. …
Benznidazole
Benznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017. It is the first treatment made available in the United States for Chagas disease.
Approved
Investigational
Atriplex wrightii pollen
Atriplex wrightii pollen is the pollen of the Atriplex wrightii plant. Atriplex wrightii pollen is mainly used in allergenic testing.
Approved
Alnus rhombifolia pollen
Alnus rhombifolia pollen is the pollen of the Alnus rhombifolia plant. Alnus rhombifolia pollen is mainly used in allergenic testing.
Approved
Helianthus annuus pollen
Helianthus annuus pollen is the pollen of the Helianthus annuus plant. Helianthus annuus pollen is mainly used in allergenic testing.
Approved
Modified vaccinia ankara
Modified Vaccinia Ankara (MVA) refers to an attenuated strain of the Vaccinia virus. Vaccines using MVA are live and non-replicating, and are produced using Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN).[L42660,L42670]
Approved
Ciprocinonide
Approved
Investigational
Agrostis gigantea pollen
Agrostis gigantea pollen is the pollen of the Agrostis gigantea plant. Agrostis gigantea pollen is mainly used in allergenic testing.
Approved
Influenza B virus B/Washington/02/2019 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Gimeracil
Gimeracil is an adjunct to antineoplastic therapy, used to increase the concentration and effect of the main active componets within chemotherapy regimens. Approved by the European Medicines Agency (EMA) in March 2011, Gimeracil is available in combination with DB03209 and DB09256 within the commercially available product "Teysuno". The main active...
Approved
Matched Description: … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, ... This allows higher concentrations of 5-FU to be achieved with a lower dose of tegafur, thereby also reducing …
Decitabine
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Description: … Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying ... proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a …
Mecasermin
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Description: … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a …
Daratumumab
Daratumumab is an immunoglobulin G1 kappa monoclonal antibody developed by Janssen and Genmab. It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind. Daratumumab was granted FDA approval on 16 November 2015. It is approved for...
Approved
Matched Description: … [A7935] It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ …
Etafedrine
Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin and Dalmacol . It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued .
Ethylephedrine is...
Approved
Matched Description: … Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... The hydrochloride is be prepared by passing hydrogen chloride through a solution of ethylephedrine in …
Fraxinus americana pollen
Fraxinus americana pollen is the pollen of the Fraxinus americana plant. Fraxinus americana pollen is mainly used in allergenic testing.
Approved
Displaying drugs 3626 - 3650 of 11853 in total