Displaying drugs 26 - 50 of 1334 in total
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … of at least 5%. ... ion transporter present on cell membranes. ... Lumacaftor is a drug used in combination with [DB08820] as the fixed dose combination product Orkambi …
Matched Categories: … ivacaftor and lumacaftor ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … of at least 5%. ... ion transporter present on cell membranes. ... Lumacaftor is a drug used in combination with [DB08820] as the fixed dose combination product Orkambi …
Matched Categories: … ivacaftor and lumacaftor ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Sparfloxacin
Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
Approved
Investigational
Withdrawn
Matched Synonyms: … cis-5-Amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic …
Matched Iupac: … 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline- ... 3-carboxylic acid …
Matched Description: … deactivation, and transcription. ... Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. ... Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline- ... 3-carboxylic acid …
Matched Description: … deactivation, and transcription. ... Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. ... Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ibrexafungerp
Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection.[A235384,L34349] It was developed out of a need to treat fungal infections that may have become resistant to echinocandins or azole...
Approved
Investigational
Matched Synonyms: … -8- ((2R)-3-METHYLBUTAN-2-YL)-14-(5-(PYRIDIN-4-YL)-1H-1,2,4- TRIAZOL-1-YL)-1,6,6A,7,8,9,10,10A,10B,11,12,12A-DODECAHYDRO ... enfumafungin derivative B-(1,3)-D-glucan synthestis inhibitor ... (1S,4AR,6AS,7R,8R,10AR,10BR,12AR,14R,15R)-15-((2R)- 2-AMINO-2,3,3-TRIMETHYLBUTOXY)-1,6A,8,10A-TETRAMETHYL …
Matched Iupac: … -[(2R)-3-methylbutan-2-yl]-20-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-17-oxapentacyclo[13.3.3.0^{1,14 ... (1R,5S,6R,7R,10R,11R,14R,15S,20R,21R)-21-[(2R)-2-amino-2,3,3-trimethylbutoxy]-5,7,10,15-tetramethyl-7 ... }.0^{2,11}.0^{5,10}]henicos-2-ene-6-carboxylic acid …
Matched Description: … [A235414,L34349] Ibrexafungerp was granted FDA approval on 1 June 2021.[L34349] ... A235384] Ibrexafungerp is orally bioavailable compared to the echinocandins [caspofungin], [micafungin], and ... approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection …
Matched Salts cas: … 1965291-14-8 …
Matched Iupac: … -[(2R)-3-methylbutan-2-yl]-20-[5-(pyridin-4-yl)-1H-1,2,4-triazol-1-yl]-17-oxapentacyclo[13.3.3.0^{1,14 ... (1R,5S,6R,7R,10R,11R,14R,15S,20R,21R)-21-[(2R)-2-amino-2,3,3-trimethylbutoxy]-5,7,10,15-tetramethyl-7 ... }.0^{2,11}.0^{5,10}]henicos-2-ene-6-carboxylic acid …
Matched Description: … [A235414,L34349] Ibrexafungerp was granted FDA approval on 1 June 2021.[L34349] ... A235384] Ibrexafungerp is orally bioavailable compared to the echinocandins [caspofungin], [micafungin], and ... approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection …
Matched Salts cas: … 1965291-14-8 …
Quizartinib
Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated with other targets in mind. Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although...
Approved
Investigational
Matched Synonyms: … N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol- ... 2-yl)phenyl)urea …
Matched Iupac: … 3-(5-tert-butyl-1,2-oxazol-3-yl)-1-(4-{10-[2-(morpholin-4-yl)ethoxy]-7-thia-2,5-diazatricyclo[6.4.0.0²,⁶ ... ]dodeca-1(8),3,5,9,11-pentaen-4-yl}phenyl)urea …
Matched Description: … Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug ... duplication (ITD), although with a 10-fold lower affinity compared to wild-type FLT3. ... AML, where quizartinib combined with standard cytarabine and anthracycline induction and standard cytarabine …
Matched Salts cas: … 1132827-21-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 3-(5-tert-butyl-1,2-oxazol-3-yl)-1-(4-{10-[2-(morpholin-4-yl)ethoxy]-7-thia-2,5-diazatricyclo[6.4.0.0²,⁶ ... ]dodeca-1(8),3,5,9,11-pentaen-4-yl}phenyl)urea …
Matched Description: … Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug ... duplication (ITD), although with a 10-fold lower affinity compared to wild-type FLT3. ... AML, where quizartinib combined with standard cytarabine and anthracycline induction and standard cytarabine …
Matched Salts cas: … 1132827-21-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Itraconazole
First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Synonyms: … (SUP 2)-1,2,4-TRIAZOLIN-5-ONE ... 3H-1,2,4-TRIAZOL-3-ONE, 4-(4-(4-(4-((2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN ... (±)-1-SEC-BUTYL-4-(P-(4-(P-(((2R*,4S*)-2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN …
Matched Iupac: … 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan ... -4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one …
Matched Description: … [A34257] It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each ... [L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. ... to treat a variety of infections. …
Matched Mixtures name: … Ciclopirox 3% / Itraconazole 5% / Urea 20% ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … 14-alpha Demethylase Inhibitors ... Heterocyclic Compounds, 1-Ring ... Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … SEMPERA 7 ... FUNGITRAL - ITRACONAZOL 1% SOLUCION ORAL …
Matched Iupac: … 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan ... -4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one …
Matched Description: … [A34257] It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each ... [L50051] Itraconazole was first approved in the US in 1992 [L50056] and is available orally. ... to treat a variety of infections. …
Matched Mixtures name: … Ciclopirox 3% / Itraconazole 5% / Urea 20% ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Categories: … 14-alpha Demethylase Inhibitors ... Heterocyclic Compounds, 1-Ring ... Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … SEMPERA 7 ... FUNGITRAL - ITRACONAZOL 1% SOLUCION ORAL …
Vorapaxar
Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
Approved
Matched Synonyms: … [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-Fluorophényl)-2-pyridinyl]vinyl}-1-méthyl-3-oxododécahydronaphto ... Ethyl N-[(3R,3aS,4S,4aR,7R,8aR,9aR)-4-[(E)-2-[5-(3-fluorophenyl)-2-pyridyl]vinyl]-3-methyl-1-oxo-3a,4,4a ... Carbamic acid, [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2- pyridinyl]ethenyl]dodecahydro …
Matched Iupac: … ethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-dodecahydronaphtho …
Matched Description: … By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related ... Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) ... indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history …
Matched Categories: … Blood and Blood Forming Organs ... Heterocyclic Compounds, 1-Ring ... Protease-activated Receptor-1 Antagonist ... Protease-activated Receptor-1 Antagonists ... Receptor, PAR-1, antagonists & inhibitors …
Matched Iupac: … ethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-dodecahydronaphtho …
Matched Description: … By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related ... Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) ... indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history …
Matched Categories: … Blood and Blood Forming Organs ... Heterocyclic Compounds, 1-Ring ... Protease-activated Receptor-1 Antagonist ... Protease-activated Receptor-1 Antagonists ... Receptor, PAR-1, antagonists & inhibitors …
Cloxacillin
A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1- ... (3-(o-chlorophenyl)-5-methyl-4-isoxazolyl)penicillin ... 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Description: … A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin]. …
Matched Salts cas: … 23736-58-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ./5 มล.) ... OXACIL GRANULES 125 MG/ 5 ML ... CLOXACILLA POWDER FOR SYRUP 125 MG / 5 ML …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Description: … A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin]. …
Matched Salts cas: … 23736-58-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ./5 มล.) ... OXACIL GRANULES 125 MG/ 5 ML ... CLOXACILLA POWDER FOR SYRUP 125 MG / 5 ML …
Ivabradine
Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus...
Approved
Matched Synonyms: … -2,3,4,5-tetrahydro-1H-3-benzazepin-2-one ... 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy …
Matched Iupac: … -2,3,4,5-tetrahydro-1H-3-benzazepin-2-one ... 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy …
Matched Description: … Therefore, as ivabradine is designed as a "pure" heart rate-lowering drug by selectively acting on the ... dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the myocardium ... and symptomatic chronic heart failure. …
Matched Salts cas: … 1086026-42-7 …
Matched Mixtures name: … CARIVALAN 25/5 ... CARIVALAN 6.25/5 ... CARIVALAN 12.5/5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... metoprolol and ivabradine ... carvedilol and ivabradine …
Matched Products: … FARCOR 5 ... บราลอน 5 ... CORALAN 5 MG …
Matched Iupac: … -2,3,4,5-tetrahydro-1H-3-benzazepin-2-one ... 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy …
Matched Description: … Therefore, as ivabradine is designed as a "pure" heart rate-lowering drug by selectively acting on the ... dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the myocardium ... and symptomatic chronic heart failure. …
Matched Salts cas: … 1086026-42-7 …
Matched Mixtures name: … CARIVALAN 25/5 ... CARIVALAN 6.25/5 ... CARIVALAN 12.5/5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... metoprolol and ivabradine ... carvedilol and ivabradine …
Matched Products: … FARCOR 5 ... บราลอน 5 ... CORALAN 5 MG …
Dicloxacillin
One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4- ... thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … (2S,5R,6R)-6-[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Salts cas: … 343-55-5 ... 13412-64-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … DICLOXACILINA 250 MG POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL ... DICLOXACILINA 125 MG / 5 ML ... DICLOCIL SUSPENSION ORAL 250 MG/5 ML …
Matched Iupac: … (2S,5R,6R)-6-[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Salts cas: … 343-55-5 ... 13412-64-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … DICLOXACILINA 250 MG POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL ... DICLOXACILINA 125 MG / 5 ML ... DICLOCIL SUSPENSION ORAL 250 MG/5 ML …
Buprenorphine
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 21-cyclopropyl-7α-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine ... 2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2 ... 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12 …
Matched Iupac: … (1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13 ... -oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^{1,6}.0^{6,14}.0^{7,12}]icosa-7,9,11-trien-11-ol …
Matched Description: … 4:1 fixed-dose combination product along with [naloxone], a non-selective competitive opioid receptor ... with a lower risk of overdose and respiratory depression. ... pain and opioid use disorder), as it has less effect on Qtc interval prolongation,[A186271,A186274] …
Matched Salts cas: … 53152-21-9 …
Matched Mixtures name: … SUBOXONE 8 MG/2 MG DILALTI TABLET, 7 ADET ... SUBOXONE 2 MG/0,5 MG DILALTI TABLET, 7 ADET ... Bupensan Duo 4 mg/1 mg-Sublingualtabletten …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Products: … BUPRE-HEXAL 7 T 5 UG/H ... Bupensan 1 mg-Sublingualtabletten ... BUPENSAN 2 MG …
Matched Iupac: … (1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13 ... -oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^{1,6}.0^{6,14}.0^{7,12}]icosa-7,9,11-trien-11-ol …
Matched Description: … 4:1 fixed-dose combination product along with [naloxone], a non-selective competitive opioid receptor ... with a lower risk of overdose and respiratory depression. ... pain and opioid use disorder), as it has less effect on Qtc interval prolongation,[A186271,A186274] …
Matched Salts cas: … 53152-21-9 …
Matched Mixtures name: … SUBOXONE 8 MG/2 MG DILALTI TABLET, 7 ADET ... SUBOXONE 2 MG/0,5 MG DILALTI TABLET, 7 ADET ... Bupensan Duo 4 mg/1 mg-Sublingualtabletten …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Products: … BUPRE-HEXAL 7 T 5 UG/H ... Bupensan 1 mg-Sublingualtabletten ... BUPENSAN 2 MG …
Propafenone
An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Approved
Matched Synonyms: … 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone ... 2-(2'-hydroxy-3'-propylaminopropoxy)-ω-phenylpropiophenone …
Matched Iupac: … 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one …
Matched Salts cas: … 34183-22-7 …
Matched Iupac: … 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one …
Matched Salts cas: … 34183-22-7 …
Chlorpheniramine
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Synonyms: … 1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane ... 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine ... 3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine …
Matched Iupac: … [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. ... One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and …
Matched Salts cas: … 25387-68-2 ... 1405-56-7 ... 56343-98-7 …
Matched Mixtures name: … A-FERİN 1 MG +160 MG/5 ML PEDİYATRİK ŞURUP, 100 ML ... A-FERİN PLUS 1 MG +15 MG+160 MG/5 ML PEDİYATRİK ŞURUP,100 ML ... CLORFENIRAMINA MALEATO 2 MG. Y CAFEINA ANHIDRA 5 MG. GRANULADO PARA RECONSTITUIR SABOR LIMON- MIEL. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ALERFIN 2 MG/5 ML ORAL ÇÖZELTI, 1 ŞIŞE ... CLORFENIRAMINA JARABE 2 MG / 5 ML ... CLORFENIRAMINA MALEATO 2 MG / 5 ML …
Matched Iupac: … [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. ... One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and …
Matched Salts cas: … 25387-68-2 ... 1405-56-7 ... 56343-98-7 …
Matched Mixtures name: … A-FERİN 1 MG +160 MG/5 ML PEDİYATRİK ŞURUP, 100 ML ... A-FERİN PLUS 1 MG +15 MG+160 MG/5 ML PEDİYATRİK ŞURUP,100 ML ... CLORFENIRAMINA MALEATO 2 MG. Y CAFEINA ANHIDRA 5 MG. GRANULADO PARA RECONSTITUIR SABOR LIMON- MIEL. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ALERFIN 2 MG/5 ML ORAL ÇÖZELTI, 1 ŞIŞE ... CLORFENIRAMINA JARABE 2 MG / 5 ML ... CLORFENIRAMINA MALEATO 2 MG / 5 ML …
Tegaserod
Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine …
Matched Iupac: … N'-[(E)-[(5-methoxy-1H-indol-3-yl)methylidene]amino]-N-pentylguanidine …
Matched Description: … serotonin-4 (5-HT(4)) receptors in smooth muscle cells and in the gastrointestinal wall to facilitate ... whom are considered to be at a lower risk of a cardiovascular event than the broader population. ... originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with …
Matched Categories: … Alimentary Tract and Metabolism ... Heterocyclic Compounds, 2-Ring ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Iupac: … N'-[(E)-[(5-methoxy-1H-indol-3-yl)methylidene]amino]-N-pentylguanidine …
Matched Description: … serotonin-4 (5-HT(4)) receptors in smooth muscle cells and in the gastrointestinal wall to facilitate ... whom are considered to be at a lower risk of a cardiovascular event than the broader population. ... originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with …
Matched Categories: … Alimentary Tract and Metabolism ... Heterocyclic Compounds, 2-Ring ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Dihydroergotamine
A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile.
Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Synonyms: … 5'-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman ... (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6] ... 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione …
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6 ... }]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene …
Matched Description: … an increase of 3-fold in Cmax and 4-fold in AUC despite the solution formulated at 75% of the strength ... A 9,10alpha-dihydro derivative of [ergotamine]. ... approved Precision Olfactory Delivery technology developed by Impel Neuropharma technology has correlated with …
Matched Salts cas: … 6190-39-2 ... 5989-77-5 …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Adrenergic alpha-1 Receptor Antagonists ... Ergot Alkaloids and Derivatives ... Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Agonists …
Matched Iupac: … (2R,4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6 ... }]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene …
Matched Description: … an increase of 3-fold in Cmax and 4-fold in AUC despite the solution formulated at 75% of the strength ... A 9,10alpha-dihydro derivative of [ergotamine]. ... approved Precision Olfactory Delivery technology developed by Impel Neuropharma technology has correlated with …
Matched Salts cas: … 6190-39-2 ... 5989-77-5 …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Adrenergic alpha-1 Receptor Antagonists ... Ergot Alkaloids and Derivatives ... Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Agonists …
Pyrithione
Pyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. In the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat...
Approved
Matched Synonyms: … 2-pyridinethiol 1-oxide …
Matched Iupac: … 2-sulfanylpyridin-1-ium-1-olate …
Matched Description: … ligands chelated to zinc (2+) ions via oxygen and sulfur centers. ... Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused ... In the crystalline state, it exists as a centrosymmetric dimer. …
Matched Salts cas: … 3811-73-2 ... 13463-41-7 …
Matched Mixtures name: … D-COL Personal Hygiene Convenience kit ... Head and Shoulders Hair Thickening System with Biotin ... Head and Shoulders Hair Thickening System with Biotin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Head and Shoulders 3 In 1 Men ... Or D. Hair ... ESIKA Vital With Active Z 2-in-1 Dandruff Control …
Matched Iupac: … 2-sulfanylpyridin-1-ium-1-olate …
Matched Description: … ligands chelated to zinc (2+) ions via oxygen and sulfur centers. ... Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused ... In the crystalline state, it exists as a centrosymmetric dimer. …
Matched Salts cas: … 3811-73-2 ... 13463-41-7 …
Matched Mixtures name: … D-COL Personal Hygiene Convenience kit ... Head and Shoulders Hair Thickening System with Biotin ... Head and Shoulders Hair Thickening System with Biotin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Head and Shoulders 3 In 1 Men ... Or D. Hair ... ESIKA Vital With Active Z 2-in-1 Dandruff Control …
Cefapirin
Cefapirin (INN, also spelled cephapirin), commonly marketed under the trade name Cefadyl, is a first-generation cephalosporin antibiotic that is available in injectable formulations. Production for use in humans has been discontinued in the United States. Cefapirin is partly plasma-bound and is effective against gram-negative and gram-positive organisms.
Approved
Vet approved
Matched Synonyms: … (6R,7R)-3-(acetoxymethyl)-8-oxo-7-{[(pyridin-4-ylsulfanyl)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct ... -2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(pyridin-4-ylsulfanyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct ... -2-ene-2-carboxylic acid …
Matched Description: … Cefapirin is partly plasma-bound and is effective against gram-negative and gram-positive organisms. ... Cefapirin (INN, also spelled cephapirin), commonly marketed under the trade name Cefadyl, is a first-generation …
Matched Salts cas: … 24356-60-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(pyridin-4-ylsulfanyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct ... -2-ene-2-carboxylic acid …
Matched Description: … Cefapirin is partly plasma-bound and is effective against gram-negative and gram-positive organisms. ... Cefapirin (INN, also spelled cephapirin), commonly marketed under the trade name Cefadyl, is a first-generation …
Matched Salts cas: … 24356-60-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Darifenacin
Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence.
Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. This block reduces the urgency to urinate and so it should not be used in people with urinary retention.
It is unknown if M3 receptor selectivity is clinically...
Approved
Investigational
Matched Synonyms: … (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamide …
Matched Iupac: … 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide …
Matched Description: … This block reduces the urgency to urinate and so it should not be used in people with urinary retention ... Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. …
Matched Salts cas: … 133099-07-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … DASİN 15 MG UZATILMIŞ SALIMLI TABLET, 14 TABLET ... DASİN 7,5 MG UZATILMIŞ SALIMLI TABLET, 14 TABLET …
Matched Iupac: … 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide …
Matched Description: … This block reduces the urgency to urinate and so it should not be used in people with urinary retention ... Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. …
Matched Salts cas: … 133099-07-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … DASİN 15 MG UZATILMIŞ SALIMLI TABLET, 14 TABLET ... DASİN 7,5 MG UZATILMIŞ SALIMLI TABLET, 14 TABLET …
Mezlocillin
Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Approved
Investigational
Matched Synonyms: … ]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-3,3-dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl ... 6β-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid …
Matched Iupac: … dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-[(3-methanesulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-3,3- …
Matched Description: … It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and …
Matched Salts cas: … 42057-22-7 ... 80495-46-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Penicillins With Extended Spectrum …
Matched Iupac: … dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-[(3-methanesulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-3,3- …
Matched Description: … It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and …
Matched Salts cas: … 42057-22-7 ... 80495-46-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Penicillins With Extended Spectrum …
Tadalafil
Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Synonyms: … (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b ... (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido( …
Matched Iupac: … (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca ... -1(10),11,13,15-tetraene-4,7-dione …
Matched Description: … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction ... a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment ... (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... 5-alpha Reductase Inhibitors ... Phosphodiesterase 5 Inhibitors …
Matched Products: … N/A ... REKFİL 5 MG TABLET, 14 ADET ... LONGIVO 5 MG TABLET, 14 ADET …
Matched Iupac: … (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca ... -1(10),11,13,15-tetraene-4,7-dione …
Matched Description: … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction ... a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment ... (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... 5-alpha Reductase Inhibitors ... Phosphodiesterase 5 Inhibitors …
Matched Products: … N/A ... REKFİL 5 MG TABLET, 14 ADET ... LONGIVO 5 MG TABLET, 14 ADET …
Salicylic acid
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Synonyms: … 2-Carboxyphenol ... 2-Hydroxybenzoic acid …
Matched Iupac: … 2-hydroxybenzoic acid …
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically ... It has bacteriostatic, fungicidal, and keratolytic actions. …
Matched Salts cas: … 54-21-7 ... 4419-92-5 ... 64425-90-7 …
Matched Mixtures name: … Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Urea 39.5% with 2% Salicylic Acid …
Matched Categories: … Non COX-2 selective NSAIDS ... Salicylic Acid and Derivatives ... sodium salicylate and methenamine ... Genito Urinary System and Sex Hormones …
Matched Products: … ASD 3-in-1 ... Clean and Clear Advantage 3 in 1 Foaming Acne Wash ... 3 in 1 Cleanser …
Matched Iupac: … 2-hydroxybenzoic acid …
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically ... It has bacteriostatic, fungicidal, and keratolytic actions. …
Matched Salts cas: … 54-21-7 ... 4419-92-5 ... 64425-90-7 …
Matched Mixtures name: … Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Urea 39.5% with 2% Salicylic Acid …
Matched Categories: … Non COX-2 selective NSAIDS ... Salicylic Acid and Derivatives ... sodium salicylate and methenamine ... Genito Urinary System and Sex Hormones …
Matched Products: … ASD 3-in-1 ... Clean and Clear Advantage 3 in 1 Foaming Acne Wash ... 3 in 1 Cleanser …
Hetacillin
Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative...
Approved
Vet approved
Withdrawn
Matched Synonyms: … (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... 6β-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]penicillanic acid ... [3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Description: … Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused ... Hetacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria ... The bactericidal activity of Hetacillin results from the inhibition of cell wall synthesis and is mediated …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Penicillins With Extended Spectrum …
Matched Iupac: … (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... [3.2.0]heptane-2-carboxylic acid …
Matched Description: … Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused ... Hetacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria ... The bactericidal activity of Hetacillin results from the inhibition of cell wall synthesis and is mediated …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Penicillins With Extended Spectrum …
Dronedarone
Dronedarone is a Class III antiarrhythmic drug that works to restore the normal sinus rhythm in patients with paroxysmal or persistent atrial fibrillation. Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke prevention and symptom management. It is managed by rate control, rhythm control, prevention...
Approved
Matched Synonyms: … N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-methanesulfonamide ... N-(2-butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide …
Matched Iupac: … N-(2-butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide …
Matched Description: … Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke ... with paroxysmal or persistent atrial fibrillation. ... lacks iodine moieties which are associated with amiodarone-induced thyroid problems. …
Matched Categories: … Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … N-(2-butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide …
Matched Description: … Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke ... with paroxysmal or persistent atrial fibrillation. ... lacks iodine moieties which are associated with amiodarone-induced thyroid problems. …
Matched Categories: … Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 2-Ring …
Amlodipine
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched International brands: … Amlodipine 5 ... Amlodipin-Mepha 5/10 …
Matched Synonyms: … (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate ... 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … a lower incidence of myocardial depression and cardiac conduction abnormalities than other calcium channel ... selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with ... Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the …
Matched Salts cas: … 652969-01-2 …
Matched Mixtures name: … VIACORAM TABLET 7 MG/ 5 MG ... CARDIK ® 3 160/5/12.5 ... Viacoram 7 mg/5 mg Tabletten …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Selective Calcium Channel Blockers With Mainly Vascular Effects ... losartan and amlodipine ... ramipril and amlodipine ... nebivolol and amlodipine …
Matched Products: … A-B VASK 5 ... PRESONE-1 ... A-B VASK 10 …
Matched Synonyms: … (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate ... 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … a lower incidence of myocardial depression and cardiac conduction abnormalities than other calcium channel ... selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with ... Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the …
Matched Salts cas: … 652969-01-2 …
Matched Mixtures name: … VIACORAM TABLET 7 MG/ 5 MG ... CARDIK ® 3 160/5/12.5 ... Viacoram 7 mg/5 mg Tabletten …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Selective Calcium Channel Blockers With Mainly Vascular Effects ... losartan and amlodipine ... ramipril and amlodipine ... nebivolol and amlodipine …
Matched Products: … A-B VASK 5 ... PRESONE-1 ... A-B VASK 10 …
Oxybenzone
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Synonyms: … 2-Benzoyl-5-methoxyphenol ... Benzophenone-3 ... 2-Hydroxy-4-methoxybenzophenone …
Matched Iupac: … 2-benzoyl-5-methoxyphenol …
Matched Description: … It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays ... It is a derivative of benzophenone. …
Matched Mixtures name: … Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (rose 5) ... Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (beige 5) ... Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (rose 2) …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … 2-benzoyl-5-methoxyphenol …
Matched Description: … It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays ... It is a derivative of benzophenone. …
Matched Mixtures name: … Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (rose 5) ... Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (beige 5) ... Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (rose 2) …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Mupirocin
Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative...
Approved
Investigational
Vet approved
Matched Synonyms: … 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3- [(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl] ... oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid ... Pseudomonic acid A …
Matched Iupac: … 9-{[(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-{[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl ... }oxan-2-yl]-3-methylbut-2-enoyl]oxy}nonanoic acid …
Matched Description: … Mupirocin, formerly termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique ... antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative ... the activity of bacterial isoleucyl-tRNA synthetase, mupirocin does not demonstrate cross-resistance with …
Matched Mixtures name: … Pre and Post Sx Pouch ... Metronidazole 1% / Mupirocin 2% / ... Metronidazole 1% / Mupirocin 2% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MUPIGEN %2 POMAD , 15 G'LIK 1 TÜP ... Mupirocin 2% ... Bactroban 2 % - Creme …
Matched Iupac: … 9-{[(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-{[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl ... }oxan-2-yl]-3-methylbut-2-enoyl]oxy}nonanoic acid …
Matched Description: … Mupirocin, formerly termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique ... antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative ... the activity of bacterial isoleucyl-tRNA synthetase, mupirocin does not demonstrate cross-resistance with …
Matched Mixtures name: … Pre and Post Sx Pouch ... Metronidazole 1% / Mupirocin 2% / ... Metronidazole 1% / Mupirocin 2% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MUPIGEN %2 POMAD , 15 G'LIK 1 TÜP ... Mupirocin 2% ... Bactroban 2 % - Creme …
Displaying drugs 26 - 50 of 1334 in total