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Displaying drugs 26 - 50 of 755 in total

Stannous fluoride

Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective...
Approved
Matched Description: … Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient ... It manages and prevents dental caries and gingivitis by promoting enamel mineralization [A19580], reducing ... compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up Anticavity Toothpaste Multi Function ... Sensodyne Sensitivity and Gum Clean and Fresh ... Crest Sensi-Repair and Prevent …

Petrolatum

A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Description: … It is used as an ointment base, topical protectant, and lubricant. …
Matched Mixtures name: … Ice Lipbalm - Stk Top ... Lil Goats Zinc Oxide ... Ice Lipbalm SPF 12- Stk Top …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Resurfix Elemental Silver Healing ... Vitamin A and D ... A and D …

Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Salicylic acid

A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically ... It has bacteriostatic, fungicidal, and keratolytic actions. …
Matched Mixtures name: … Dermaharmony Sulfur and Salicylic Acid ... Dermaharmony Sulfur and Salicylic Acid ... NW SULPHUR 2%W/W AND SALICYLIC ACID 2%W/W CREAM …
Matched Salts name: … Sodium salicylate …
Matched Categories: … Salicylic Acid and Derivatives ... sodium salicylate …
Matched Products: … Sulfur 8 Loc Twist and Braid Scalp ... Naturopathica Colloidal Silver and Salicylic Acid Acne Clearing Cleanser ... Sulfur 8 Fresh Anti-Dandruff Hair and Scalp Conditioner …

Givastomig

Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody.
Investigational
Matched Synonyms: … an anti-Claudin 18.2 and 4.1BB Bispecific Antibody …
Matched Description: … Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody. …

Moroctocog alfa

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Moroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and ... prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …

Lonoctocog alfa

Approved
Investigational
Matched Products: … AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000IU/VIAL …

Padimate O

Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic ... Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in …
Matched Mixtures name: … Sun and Ski Stick SPF 15 ... Aruba Aloe Lip Sunscreen and Moisturizer ... Phineas and Ferb Sun Smacker SPF 24 Berry Busted …
Matched Products: … Hand and Body Lotion SPF 15 ... Green Tea and Ginkgo Moisturizer SPF 10 ... Medicated Lip Balm - Ont Top 8% …

Sodium fluorophosphate

Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Approved
Matched Synonyms: … Sodium monofluorophosphate …
Matched Name: … Sodium fluorophosphate …
Matched Description: … Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities. …
Matched Mixtures name: … Mentadent Specialty Whitening Toothpaste and Polishing ... Hawaiian Airline EC with Colgate Toothbrush and Sun ... Nano Silver Toothpaste …
Matched Categories: … Alimentary Tract and Metabolism ... sodium monofluorophosphate ... sodium monofluorophosphate …
Matched Products: … Finefra Silver ... Colgate Sparkling White Mint Zing ... Far Infra Silver …

Rurioctocog alfa pegol

Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia A to manage and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …

Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It was also approved by FDA and EMA in 2016. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …

RP-72

Investigational
Matched Synonyms: … CXC chemokine receptor types 1 and 2 inhibitor RP72 ... 72 amino acid proprietary recombinant protein antagonist for the CXCR1 and CXCR2 receptors of interleukin …

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (40 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …

Aluminum chlorohydrate

Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Iupac: … dialuminium(3+) ion hydrate chloride pentahydroxide …
Matched Categories: … Astringents and Deodorants ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Silver Leather ... Dove Men plus Care Cool Silver Antiperspirant ... Soft and Dri Cool and Clean …

Smallpox and Monkeypox Vaccine, Live, Non-replicating

Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …

Sodium fluoride

Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Synonyms: … Sodium fluoride …
Matched Name: … Sodium fluoride …
Matched Iupac: … sodium fluoride …
Matched Description: … Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride ... , including dental care and radiographic imaging when it is used as [Fluoride ion F-18]. ... control dental caries is safe when used correctly and is highly effective in reducing the prevalence …
Matched Mixtures name: … Sodium Fluoride and Vitamin D Drops ... Sodium Fluoride and Potassium Nitrate ... Top. Gel …
Matched Categories: … Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... sodium fluoride ... sodium fluoride ... Sodium Compounds …
Matched Products: … Thixotropic Neutral Sodium Fluoride Top. Gel ... CloSYS Silver Sensitive Mouth Rinse Fluoride Rinse ... Top Quality Mfg APF …

Penicillium glaucum

Penicillium glaucum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, penicillium glaucum ... Molds, rusts and smuts, penicillium glaucus …

Hydroquinone

Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration ... As a result of these concerns, hydroquinone has been banned in the EU and UK. ... with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and …
Matched Mixtures name: … Top White ... Top White Skin Lightening ... Hyaluronic Acid Sodium Salt 1% / Hydroquinone 6% …
Matched Products: … Gold Cosmetics Bleach Cream Silver ... CONDITION AND ENHANCE CLEAR Skin Bleaching and Corrector ... CONDITION AND ENHANCE BLENDER Skin Lightener and Blending …

PMC-403

PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Investigational
Matched Synonyms: … a fully human monoclonal antibody that binds and activates the Tie2 receptor …

TSHA-101

Investigational
Matched Synonyms: … adeno-associated viral vector serotype 9 (AAV9) carrying both HEXA and HEXB …

Coagulation Factor IX (Recombinant)

Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Description: … Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric ... has structural and functional characteristics similar to those of endogenous factor IX. ... has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and …
Matched Products: … BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 250iu/vial ... BeneFIX Powder and Solvent for Solution for Injection 1000iu/vial …

Heparin

Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … coagulation enzymes thrombin (factor IIa) and factor Xa. ... UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sod and 0.9% Sod Chloride Inj ... Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sodium In 0.9% Sodium Chloride Injection …
Matched Salts name: … Heparin sodium …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … Heparin Sodium and Sodium Chloride ... Heparin Sodium and Dextrose ... Heparin Sodium in Sodium Chloride …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Products: … NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... powder and solvent for solution for injection 2mg ... NOVOSEVEN 1MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Bacitracin

Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Mixtures name: … Bacitracin Zinc and Polymyxin B Sulfate ... Bacitracin Zinc and Polymyxin B Sulfate ... Bacitracin Zinc and Polymyxin B Sulfate …
Matched Salts name: … Bacitracin zinc …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Up and Up First Aid Antibiotic ... Up and Up Bacitracin first aid ... Bacitracin Zinc …
Displaying drugs 26 - 50 of 755 in total