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Displaying drugs 51 - 75 of 15197 in total
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … N-methyl-2-pyridineethanamine ... N-methyl-2-(2-pyridinyl)ethanamine …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … It has a significant impact on both the physical and social functioning of affected individuals. ... Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing …
Matched Salts name: … Betahistine hydrochloride
Matched Products: … BETAHISTINE HYDROCHLORIDE
A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Approved
Illicit
Matched Synonyms: … d-N-methyl-N-benzyl-β-phenylisopropylamine ... N-methyl-1-phenyl-N-(phenylmethyl)propan-2-amine …
Matched Iupac: … benzyl(methyl)[(2S)-1-phenylpropan-2-yl]amine …
Matched Salts name: … Benzphetamine hydrochloride
Matched Products: … Benzphetamine Hydrochloride
Vitamin K1, also called phylloquinone or phytonadione, is a fat soluble vitamin.[L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X.[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II,...
Approved
Investigational
Matched Synonyms: … 2-Methyl-3-phytyl-1,4-naphthochinon ... 2-Methyl-3-phytyl-1,4-naphthoquinone ... 2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione …
Matched Iupac: … 2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-1,4-dihydronaphthalene-1,4-dione …
Matched Description: … precursors to coagulation factors II, VII, IX, and X. ... [L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates ... the treatment of coagulation disorders due to faulty formation of coagulation factors II, VII, IX, and
Matched Mixtures name: … Vitamin D2 and K1 ... NUTRILITE CHILDREN MULTIVITAMIN AND IRON CHEWABLE TABLET …
Matched Categories: … Diet, Food, and Nutrition ... Blood and Blood Forming Organs …
An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug...
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … Methyl 1,1-difluoro-2,2-dichloroethyl ether …
Matched Description: … employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and
Matched Categories: … Methyl Ethers ... Miscellaneous Analgesics and Antipyretics …
Approved
Matched Synonyms: … N-methyl-D-glucamine …
Matched Salts name: … Methylglucamine hydrochloride
A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Matched Synonyms: … 5-ethyl-1-methyl-5-phenylbarbituric acid ... 5-Ethyl-1-methyl-5-phenyl-pyrimidine-2,4,6-trione ... 5-ethyl-1-methyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars …
Novobiocin is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) Novobiocin sodium, a salt form of novobiocin, was initially approved in September 1964...
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-β-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen …
Matched Iupac: … (3R,4S,5R,6R)-5-hydroxy-6-({4-hydroxy-3-[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamido]-8-methyl-2-oxo …
Matched Description: … Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. ... ed, p189) Novobiocin sodium, a salt form of novobiocin, was initially approved in September 1964 and
Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational
Matched Synonyms: … ((3-iodophenyl)methyl)guanidine …
Matched Iupac: … N''-[(3-iodophenyl)methyl]guanidine …
Matched Description: … Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. …
Matched Categories: … Indicators and Reagents …
Sodium tetradecyl sulfate is an anionic surface-active agent which is used for its wetting properties in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids and varicose veins . Sodium tetradecyl sulfate has been widely used since the 1950s, and in...
Approved
Matched Synonyms: … 7-Ethyl-2-methyl-4-undecanol sulfate …
Matched Description: … is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids and varicose ... sulfate is an anionic surface-active agent which is used for its wetting properties in the industry and ... Sodium tetradecyl sulfate has been widely used since the 1950s, and in 1978 the first successful report …
A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Approved
Matched Synonyms: … (5'α)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione ... 12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione ... 12'-Hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergotaman-3',6',18-trione …
Matched Iupac: … (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}] ... dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene …
Matched Description: … It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders …
Matched Mixtures name: … Ergotamine Tartrate and Caffeine ... Ergotamine Tartrate and Caffeine ... Ergotamine Tartrate and Caffeine …
Matched Categories: … Ergot Alkaloids and Derivatives …
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched Synonyms: … (+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid ... (S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid …
Matched Description: … prescription use in 1976 and then for over-the-counter (OTC) use in 1994. ... Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for ... [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has …
Matched Mixtures name: … Naproxen Sodium and Diphenhydramine Hydrochloride ... Naproxen Sodium and Pseudoephedrine Hydrochloride Sinus and Cold ... Naproxen Sodium and Pseudoephedrine Hydrochloride Sinus and Headache …
Matched Categories: … naproxen and misoprostol ... sumatriptan and naproxen ... naproxen and esomeprazole ... naproxen and diphenhydramine ... Genito Urinary System and Sex Hormones …
Matched Products: … Back and Muscle Pain ... Up and Up Naproxen sodium ... Pain and Fever Relief …
Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Synonyms: … 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine ... 8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline …
Matched Iupac: … 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine …
Matched Description: … Also withdrawn from the Canadian and UK markets. …
A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)
Approved
Matched Synonyms: … N-methyl-N'-benzhydrylpiperazine ... (N-Benzhydryl)(N'-methyl)diethylenediamine …
Matched Description: … vomiting and in motion sickness. ... A histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced …
Matched Salts name: … Cyclizine hydrochloride
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Approved
Matched Synonyms: … 2-(1-piperidinyl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate ... 2-piperidinoethyl 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylate …
Matched Iupac: … 2-(piperidin-1-yl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate …
Matched Description: … Its therapeutic usefulness and its mechanism of action are not clear. ... A drug that has been used in various urinary syndromes and as an antispasmodic. ... It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity …
Matched Salts name: … Flavoxate hydrochloride
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … Flavoxate Hydrochloride
Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.
Approved
Investigational
Matched Synonyms: … 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone …
Matched Iupac: … 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one …
Matched Description: … Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a …
Matched Categories: … Vaginal Creams, Foams, and Jellies ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched Synonyms: … O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate ... (5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester …
Matched Iupac: … methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Synonyms: … ]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid ... (2R,4R)-1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8- quinolinyl)sulfonyl …
Matched Description: … suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and
Matched Salts name: … Moxonidine hydrochloride
Matched Categories: … moxonidine and diuretics …
A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Synonyms: … 2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone ... 7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide ... 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide …
Matched Iupac: … 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide …
Matched Description: … It also tends to lower blood pressure and increase potassium loss. …
Matched Categories: … Genito Urinary System and Sex Hormones ... metolazone and potassium-sparing agents ... Gynecological Antiinfectives and Antiseptics ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
An ergot derivative that is a congener of lysergic acid diethylamide. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the...
Approved
Matched Synonyms: … 1-Methyl-D-lysergic acid butanolamide ... (+)-N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamide ... 1-Methyl-dextro-lysergic acid (+)-1-hydroxy-2-butylamide …
Matched Description: … Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin ... It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has …
Matched Categories: … Ergot Alkaloids and Derivatives …
Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Synonyms: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Iupac: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Description: … where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing and ... Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs ... [A7927] More specifically, deletions around the LREA motif in exon 19 and exon 21 L858R point mutations …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Synonyms: … 1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidine …
Matched Iupac: … dimethyl(2-{5-[(pyrrolidine-1-sulfonyl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and ... stopping the release of certain natural substances that cause pain, nausea, and other symptoms of migraine …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … (±)-2-fluoro-α-methyl-4-biphenylacetic acid ... 2-fluoro-α-methyl-(1,1'-biphenyl)-4-acetic acid …
Matched Description: … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. ... Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and ... formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Synonyms: … 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione ... 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … , Frisium, Urbanyl, and others. ... children aged two years and older. ... and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Approved
Investigational
Matched Synonyms: … (+)-(2R)-2-(2-(((R)-p-chloro-α-methyl-α-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine ... (+)-(2R)-2-[2-[[(R)-p-chloro-α-methyl-α-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine …
Matched Description: … ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and
Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Approved
Investigational
Matched Synonyms: … 1-methyl-2-(2,6-xylyloxy)ethanamine …
Matched Salts name: … Mexiletine hydrochloride
Matched Products: … Mexiletine Hydrochloride ... Mexiletine hydrochloride
Displaying drugs 51 - 75 of 15197 in total