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Displaying drugs 76 - 100 of 4204 in total
TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … and linker-payload MC-VC-PAB-MMAE. ... TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 …
Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in ... It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic ... concentrations up to 8%, as regulated by the FDA [L2153]. …
Matched Mixtures name: … Aruba Aloe Lip Sunscreen and Moisturizer ... Sun and Ski Stick SPF 15 ... Phineas and Ferb Sun Smacker SPF 24 Berry Busted …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Compounds used in a research, industrial, or household setting …
Matched Products: … Hand and Body Lotion SPF 15 ... Green Tea and Ginkgo Moisturizer SPF 10 ... Sun Pacer Protect Light Bronzing Gel Spf4 4% …
Omalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). IgE promotes the release of inflammatory mediators from mast cells and basophils during allergic and inflammatory reactions. By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its...
Approved
Investigational
Matched Description: … , and asthma. ... and inflammatory reactions. ... By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Matched Products: … Xolair 75mg Powder and Solvent for Solution for Injection ... XOLAIR 150MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Xolair 150mg Powder and Solvent for Solution for Injection …
Hydrocodone is a synthetic opioid derivative of codeine. It is commonly used in combination with acetaminophen to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by dextromethorphan in current cough and cold formulations. Hydrocodone's more potent metabolite, hydromorphone...
Approved
Illicit
Investigational
Matched Description: … Hydrocodone's more potent metabolite, [hydromorphone] has also found wide use as an analgesic and is ... by [dextromethorphan] in current cough and cold formulations. ... Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced …
Matched Mixtures name: … Theracodophen-Low-90 ... Coristine-DH Liq ... Hydrocodone bitartrate and pseudoephedrine hydrochloride solution …
Matched Salts name: … Hydrocodone hydrochloride
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives …
Matched Products: … Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate And Acetaminophen …
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … Allantoin is a substance that is endogenous to the human body and also found as a normal component of ... More specifically, allantoin is a diureide of glyoxylic acid that is produced from uric acid. ... Allantoin is found in OTC cosmetic products and other commercial products such as oral hygiene products …
Matched Mixtures name: … Triderma Protect and Heal Non- Greasy Barrier ... Dual Treatment - Cold Sore Therapy and Daily Lip Maintenance ... Essential Solution Hyaluronic Acid Mask Sheet …
Matched Categories: … Herbs and Natural Products ... Basic Ointments and Protectants …
Matched Products: … Cetaphil Baby Soothe and Protect Cream ... Healing Foot and Leg Balm ... Vesen Lab Nano Solution Repairing and Soothing Treatment Essence …
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched International brands: … AK-Dilate ... AK-Nefrin …
Matched Synonyms: … l-(3-Hydroxyphenyl)-N-methylethanolamine …
Matched Description: … the pupil,[L9413] and induce local vasoconstriction. ... Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate …
Matched Mixtures name: … Formu Care Flu and Severe Cold and Cough Night Time ... Core Values Tussin CF ... Sildec PE …
Matched Salts name: … Phenylephrine hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics ... phenylephrine and ketorolac ... Monoamine Oxidase A Substrates …
Matched Products: … First Aid Direct Nasal and Sinus Decongestant ... Up and Up Sinus PE ... CareOne Cold and Sinus …
Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Artemisia Absinthium L. …
Matched Description: … It is not an approved drug. ... Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Products: … Seborrheic Dermatitis and Psoriasis ... Seborrheic Dermatitis and Psoriasis Cream …
Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to continuously secrete the hormone progesterone during the first...
Approved
Vet approved
Matched Description: … HCG is composed of an alpha and a beta sub-unit. ... ) and follicle-stimulating hormone (FSH), as well as to the alpha sub-unit of human thyroid-stimulating ... hormone (TSH), while the beta sub­ units of these hormones differ in amino acid sequence. …
Matched Mixtures name: … . - Pws-liq
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Powder and Solvent for Solution for Injection ... Choriomon 5000 IU powder and solvent for solution for injection ... PUBERGEN 7500IU (Chorionic Gonadotropin for Injection USP 7500IU/Vial and Sodium Chloride Injection USP …
Sunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Synonyms: … Sunflower Seed Oil ... Helianthus Annuus Seed Oil ... Helianthus Annuus (Sunflower) Seed Oil …
Matched Description: … It is not an approved drug. ... Sunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Products: … OrgaPlus Super Care Balm for combination and oi ly skin type 20g ... OrgaPlus Super Care Balm for combination and oi ly skin type 14g …
TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Investigational
Matched Synonyms: … A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and
Experimental
Matched Name: … Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe) …
Matched Iupac: … .0^{2,6}.0^{16,23}.0^{18,22}.0^{11,25}]pentacosa-3(24),4,6,8,10,12,14,16,18,20-decaen-4-yl]propanoic acid
Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Some adverse effects of carbamide peroxide as a dental bleaching agent include...
Approved
Matched Description: … /or gingival irritation led by unstable and reactive H+ free radicals and low pH from prolonged use. ... As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products ... Some adverse effects of carbamide peroxide as a dental bleaching agent include dentin sensitivity and
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Ear Wax Removal Drops Up and Up ... Foster and Thrive Earwax Removal Drops ... CareOne Earwax Removal Kit, Earwax and Bulb …
Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Synonyms: … L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid ... (-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate ... Carbidopa anhydrous
Matched Iupac: … (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
Matched Description: … It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... and approved on 2014. ... Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Categories: … Aromatic L-amino Acid Decarboxylase Inhibitors ... Aromatic Amino Acid Decarboxylase Inhibitors ... Drugs that are Mainly Renally Excreted …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …
Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced...
Approved
Matched Synonyms: … Zinc (as oxide) ... Zinc (as zinc oxide) …
Matched Description: … It is also widely used to treat a variety of other skin conditions, in products such as baby powder and ... lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and ... barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments …
Matched Mixtures name: … Mineral Oil, Pramoxine Hydrochloride and Zinc Oxide ... Aveeno Calamine and Pramoxine Hydrochloride Anti Itch ... g and h Protect Body …
Matched Categories: … Basic Powders and Demulcents ... Basic Ointments and Protectants ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Compounds used in a research, industrial, or household setting …
Matched Products: … Shea Moisture Gotu Kola and Raspberry Seed Oil Broad Spectrum SPF 25 Daily Sunscreen ... Shea Moisture Gotu Kola and Raspberry Seed Oil Broad Spectrum SPF 20 Daily Sunscreen ... Bare Republic SPF 30 Mineral Sunscreen Citrus Cooler …
Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing ... Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant …
Matched Products: … Skin So Soft Soft and Sensual Anti-Perspirant Deodorant ... Skin So Soft Fresh and Smooth Moisturizing Hair Minimizing Anti-Perspirant Deodorant …
Linvoseltamab is an investigational bispecific antibody. It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing T cells.
Investigational
Matched Synonyms: … human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMA …
Matched Description: … Linvoseltamab is an investigational bispecific antibody. …
GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic correction.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype rh79 (AAVrh.79) vectors: AAVrh79.TBG.M2PCSK9.WPRE.bGH and
Matched Description: … PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic ... GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized …
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched International brands: … Ala-Scalp …
Matched Iupac: … 1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … [A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. ... [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named ... Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. …
Matched Mixtures name: … Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... Hydrocortisone and derivatives ... hydrocortisone and mydriatics ... hydrocortisone and antiseptics …
Matched Products: … Weeks and Leo Anti-itch ... HYDROCORTISON ACIS 10MG ... Cortenema Sus 100mg/60ml …
Approved
Experimental
Matched Products: … Dr.g Lock and More Nourishing Mask ... Dr.g Lock and More Sensi Calming Mask ... PLAY and JOY Cologne Maca Extra Hot Lubricant PJ-LBS201-35EU …
Investigational
Matched Synonyms: … IgG1 antibody inhibiting PD-L1 and CTLA-4 ... FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific …
Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts .
Approved
Matched Description: … and deodorant agent. ... Aluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent …
Matched Mixtures name: … Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN …
Matched Products: … Cyzone Blue and Blue for Him ... Fraicheur Verveine Antiperspirant and Deodorant Roll-ON ... Cyzone Blue and Blue for Her …
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Synonyms: … F8 protein, human …
Matched Description: … a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential ... as a result, leads to easy bruising and bleeding. ... results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of fibrinogen …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Hemophilia A ... Proteins ... Blood Proteins
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... Octanate 500IU Powder and Solvent for Solution for Injection …
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Description: … and induces tumour cell death. ... penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and [docetaxel]. ... [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) ... Cabazred 60mg/1.5ml Concentrate And Solvent For Solution For Infusion …
AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 ... AMG-424 …
Matched Name: … AMG 424 …
Matched Description: … AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple …
NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … gene and messenger RNA (mRNA000042) encoding Cas9. ... NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 ... It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce …
Displaying drugs 76 - 100 of 4204 in total