Zinc oxide

Identification

Name
Zinc oxide
Accession Number
DB09321
Type
Small Molecule
Groups
Approved
Description

Zinc oxide is an inorganic compound with the formula ZnO. ZnO is a white powder that is insoluble in water, and it is widely used as an additive in numerous materials and products including rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced synthetically. It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments.

Structure
Thumb
Synonyms
  • óxido de cinc
  • oxyde de zinc
  • Zinc (as oxide)
  • Zinc (as zinc oxide)
  • Zinc white
  • Zinci oxydum
  • Zincum oxydatum
  • Zinkoxid
External IDs
C.I. 77947 / C.I. pigment white 4 / CI 77947
Active Moieties
NameKindUNIICASInChI Key
ZincunknownJ41CSQ7QDS7440-66-6HCHKCACWOHOZIP-UHFFFAOYSA-N
Zinc cationionic13S1S8SF3723713-49-7PTFCDOFLOPIGGS-UHFFFAOYSA-N
Product Images
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
MezincPlaster28.3 %TopicalAbigo Medical AbNot applicableNot applicableCanada
ZincofaxOintment15 %TopicalWarner Lambert Canada Inc.Not applicableNot applicableCanada
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
100% Pure Argan Oil Moisturizer SPF 30Lotion20 mg/1mLTopicalPurity Cosmetics2014-09-032017-05-01Us
100% Pure Sweet Mint Lip Balm SPF 15Stick87 mg/1gTopicalPurity Cosmetics2017-05-01Not applicableUs
100% Pure Yerba Mate MIst SPF 30Aerosol, spray120 mg/1mLTopicalPurity Cosmetics2017-05-01Not applicableUs
1000 Roses CC Color plus Correct Sheer Nude SPF 30Lotion200 mg/1mLTopicalAndalou Naturals2014-03-01Not applicableUs
1000 Roses CC Color Plus Correct Sheer Tan SPF 30Lotion200 mg/1mLTopicalAndalou Naturals2014-03-01Not applicableUs
ABC Arbonne Baby Care Sunscreen Broad Spectrum SPF 30Lotion144 mg/1mLTopicalArbonne International Llc2014-09-20Not applicableUs
ACCOJE SUNSCREEN (SPF50 Broad Spectrum)Cream4.97 g/100mLTopicalUcl Co., Ltd.2016-02-04Not applicableUs
ACTIVE ARGAN 02.3(TM) PLASMA PRO 50 FEATHERWEIGHT DAY BROAD SPECTRUM SPF 20 WITH PROPRIETARY A.P.I. and ACTIVATED ARGAN COMPLEX(TM)Cream140 mg/1mLTopicalSiborg2016-12-01Not applicableUs
Active Daily DefenseCream12 mg/100mLTopicalUrban Skin Solutions2016-07-25Not applicableUs
Active Day Cream With Uv-protectionCream2 kgTopicalBiokosma Sa1998-08-041999-09-11Canada
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
01 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUs
02 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUs
03 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUs
04 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUs
05 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUs
06 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUs
07 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUs
08 Moisture Foundation SPF 15Zinc oxide (3.9 mg/0.5mL) + Octinoxate (3.75 mg/0.5mL)EmulsionTopicalThe Body Shop, Wake Forest2009-09-06Not applicableUs
100% Pure Baby Sunscreen SPF 30Zinc oxide (25 mg/1g) + Titanium dioxide (80 mg/1g)StickTopicalPurity Cosmetics2014-09-092017-05-01Us
100% Pure Everywhere Sunscreen SPF 30Zinc oxide (25 mg/1g) + Titanium dioxide (80 mg/1g)StickTopicalPurity Cosmetics2014-09-09Not applicableUs
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Active FEZinc oxide (20 mg/1) + Ascorbic acid (160 mg/1) + Beta carotene (2100 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cupric oxide (1 mg/1) + Cyanocobalamin (30 ug/1) + DL-alpha tocopheryl acetate (40 [iU]/1) + Folic Acid (1250 ug/1) + Iron (75 mg/1) + Magnesium oxide (30 mg/1) + Nicotinamide (20 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (4 mg/1) + Thiamine hydrochloride (4 mg/1)TabletOralGm Pharmaceuticals2013-11-11Not applicableUs
Active OBZinc oxide (30 mg/1) + Ascorbic acid (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cupric sulfate pentahydrate (2 mg/1) + Cyanocobalamin (30 ug/1) + D-alpha-Tocopherol acetate (30 [iU]/1) + Doconexent (320 mg/1) + Folic Acid (1 mg/1) + Iron (20 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (4 mg/1) + Thiamine mononitrate (2 mg/1)Capsule, liquid filledOralGm Pharmaceuticals2013-10-282017-03-31Us
BacminZinc oxide (22.5 mg/1) + Ascorbic acid (500 mg/1) + Biotin (150 ug/1) + Chromium Cr-51 chloride (0.1 mg/1) + Cupric oxide (3 mg/1) + Cyanocobalamin (50 ug/1) + Ferrous fumarate (27 mg/1) + Flavone (50 mg/1) + Folic Acid (1 mg/1) + Magnesium oxide (50 mg/1) + Manganese gluconate (5 mg/1) + Nicotinamide (100 mg/1) + Calcium pantothenate (25 mg/1) + Pyridoxine hydrochloride (25 mg/1) + Riboflavin (20 mg/1) + Selenomethionine (50 ug/1) + Thiamine mononitrate (20 mg/1) + Vitamin A acetate (2000 [iU]/1) + alpha-Tocopherol acetate (30 [iU]/1)Tablet, coatedOralMarnel Pharmaceuticals, Llc2000-04-01Not applicableUs
Bal-Care DHAZinc oxide (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2850 [iU]/1) + Calcium Carbonate (219 mg/1) + Cholecalciferol (840 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (.012 mg/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic Acid (1 mg/1) + Iodine (.223 mg/1) + Iron saccharate (1.35 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (430 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Sodium feredetate (25.65 mg/1) + Thiamine mononitrate (1.8 mg/1)KitPru Gen Pharmaceuticals2012-05-01Not applicableUs
Bal-Care DHA EssentialZinc oxide (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (2850 [iU]/1) + Calcium Carbonate (219 mg/1) + Cholecalciferol (840 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (.012 mg/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic Acid (1 mg/1) + Iodine (.223 mg/1) + Iron saccharate (1.35 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (374 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Sodium feredetate (25.65 mg/1) + Thiamine mononitrate (1.8 mg/1)KitPru Gen Pharmaceuticals2012-05-01Not applicableUs
C-Nate DHAZinc oxide (20 mg/1) + Ascorbic acid (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cupric sulfate pentahydrate (1 mg/1) + Cyanocobalamin (15 ug/1) + Ferrous fumarate (28 mg/1) + Folic Acid (1 mg/1) + Magnesium (30 mg/1) + Omega-3 fatty acids (200 mg/1) + Pyridoxine hydrochloride (20 mg/1) + Riboflavin (3 mg/1) + Thiamine mononitrate (3 mg/1) + Vitamin E (30 [iU]/1)Capsule, gelatin coatedOralCenturion Labs2013-01-01Not applicableUs
Cavan AlphaZinc oxide (25 mg/1) + Ascorbic acid (120 mg/1) + Beta carotene (3000 [iU]/1) + Calcium Carbonate (230 mg/1) + Cholecalciferol (800 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (3 mg/1) + Folic Acid (1 mg/1) + Iodine (220 ug/1) + Iron (27 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (20 mg/1) + Omega-3 fatty acids (300 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (4 mg/1) + Thiamine mononitrate (1.8 mg/1)KitOralSeton Pharmaceuticals2010-07-012013-09-30Us
Cavan Folate DHAZinc oxide (25 mg/1) + Zinc oxide (25 mg/1) + Ascorbic acid (70 mg/1) + Ascorbic acid (70 mg/1) + Beta carotene (2700 [iU]/1) + Beta carotene (2700 [iU]/1) + Calcium Carbonate (100 mg/1) + Calcium Carbonate (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cupric oxide (2 mg/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (12 ug/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Doconexent (250 mg/1) + Doconexent (250 mg/1) + Ferrous fumarate (65 mg/1) + Ferrous fumarate (65 mg/1) + Folic Acid (1 mg/1) + Folic Acid (1 mg/1) + Magnesium oxide (25 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (18 mg/1) + Nicotinamide (18 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (1.8 mg/1) + Riboflavin (1.8 mg/1) + Thiamine mononitrate (1.6 mg/1) + Thiamine mononitrate (1.6 mg/1)KitSeton Pharmaceuticals2010-06-042012-03-31Us
Cavan Folate DHAZinc oxide (25 mg/1) + Zinc oxide (25 mg/1) + Ascorbic acid (70 mg/1) + Ascorbic acid (70 mg/1) + Beta carotene (2700 [iU]/1) + Beta carotene (2700 [iU]/1) + Calcium Carbonate (100 mg/1) + Calcium Carbonate (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cholecalciferol (400 [iU]/1) + Cupric oxide (2 mg/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (12 ug/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Doconexent (250 mg/1) + Doconexent (250 mg/1) + Ferrous fumarate (65 mg/1) + Ferrous fumarate (65 mg/1) + Folic Acid (1 mg/1) + Folic Acid (1 mg/1) + Magnesium oxide (25 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (18 mg/1) + Nicotinamide (18 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (1.8 mg/1) + Riboflavin (1.8 mg/1) + Thiamine mononitrate (1.6 mg/1) + Thiamine mononitrate (1.6 mg/1)KitSeton Pharmaceuticals2010-06-042012-03-31Us
Cavan Folate OBZinc oxide (25 mg/1) + Ascorbic acid (70 mg/1) + Beta carotene (2700 [iU]/1) + Calcium Carbonate (100 mg/1) + Cholecalciferol (400 [iU]/1) + Cupric oxide (2 mg/1) + Cyanocobalamin (12 ug/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Ferrous fumarate (65 mg/1) + Folic Acid (1 mg/1) + Magnesium oxide (25 mg/1) + Nicotinamide (18 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (1.8 mg/1) + Thiamine mononitrate (1.6 mg/1)TabletOralSeton Pharmaceuticals2010-08-232012-05-31Us
Categories
UNII
SOI2LOH54Z
CAS number
1314-13-2
Weight
Average: 81.408
Monoisotopic: 79.9240612
Chemical Formula
OZn
InChI Key
XLOMVQKBTHCTTD-UHFFFAOYSA-N
InChI
InChI=1S/O.Zn
IUPAC Name
oxozinc
SMILES
O=[Zn]

Pharmacology

Indication

For adjunctive treatment of diaper dermatitis. Also, it can be used to treat minor skin irritations (eg, cuts, burns, and scrapes, poison ivy). Zinc oxide can be used in ointments, creams, and lotions to protect against sunburn and other damage to the skin caused by ultraviolet light.

Associated Conditions
Pharmacodynamics

Zinc oxide has astringent, soothing and protective properties and is used in topical preparations for eczema, slight excoriations, wounds and haemorrhoids. It also reflects ultraviolet radiation and can be used as a physical sunscreen.

Mechanism of action

It acts by providing a physical barrier to prevent skin irritation and help heal damaged skin.

Absorption

No significant percutaneous absorption from topically applied zinc oxide.

Volume of distribution

Intended for local use only, no systemic absorption.

Protein binding

Intended for local use only, no systemic absorption.

Metabolism

Intended for local use only, no systemic absorption.

Route of elimination

Intended for local use only, no systemic absorption.

Half life

Intended for local use only, no systemic absorption.

Clearance

Intended for local use only, no systemic absorption.

Toxicity

Acute oral toxicity (LD50): 7950 mg/kg [Mouse].

Affected organisms
  • Humans and other mammals
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteraction
CeftibutenZinc oxide can cause a decrease in the absorption of Ceftibuten resulting in a reduced serum concentration and potentially a decrease in efficacy.
CephalexinZinc oxide can cause a decrease in the absorption of Cephalexin resulting in a reduced serum concentration and potentially a decrease in efficacy.
CinoxacinZinc oxide can cause a decrease in the absorption of Cinoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
CiprofloxacinZinc oxide can cause a decrease in the absorption of Ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
ClomocyclineZinc oxide can cause a decrease in the absorption of Clomocycline resulting in a reduced serum concentration and potentially a decrease in efficacy.
DeferiproneZinc oxide can cause a decrease in the absorption of Deferiprone resulting in a reduced serum concentration and potentially a decrease in efficacy.
DelafloxacinZinc oxide can cause a decrease in the absorption of Delafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
DemeclocyclineZinc oxide can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy.
DifloxacinZinc oxide can cause a decrease in the absorption of Difloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
DolutegravirZinc oxide can cause a decrease in the absorption of Dolutegravir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Food Interactions
Not Available

References

General References
  1. Derry JE, McLean WM, Freeman JB: A study of the percutaneous absorption from topically applied zinc oxide ointment. JPEN J Parenter Enteral Nutr. 1983 Mar-Apr;7(2):131-5. [PubMed:6406699]
  2. MSDS [Link]
  3. product info [Link]
External Links
KEGG Drug
D01170
PubChem Compound
14806
PubChem Substance
310265203
ChemSpider
14122
ChEBI
36560
ChEMBL
CHEMBL1201128
Wikipedia
Zinc_oxide
ATC Codes
C05AX04 — Zinc preparations
AHFS Codes
  • 84:24.12 — Basic Ointments and Protectants
  • 84:24.16 — Basic Powders and Demulcents
  • 84:80.00 — Sunscreen Agents
FDA label
Download (112 KB)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0CompletedOtherMelasma1
0CompletedTreatmentIntertrigo1
1RecruitingTreatmentGlioblastoma Multiforme, Adult1
1, 2RecruitingTreatmentGBM / Glioblastoma Multiforme (GBM) / Glioblastomas1
2CompletedSupportive CareAdvanced Malignant Neoplasm / Dermatologic Complication / Dermatologic Complications / Neoplasms, Malignant1
2RecruitingTreatmentAcute Gouty Arthritis1
2RecruitingTreatmentHigh Grade Glioma, Glioblastoma1
2RecruitingTreatmentMalignant Neoplasm of Stomach1
2TerminatedTreatmentMediastinal Neoplasms1
3CompletedSupportive CareDermatologic Complications / Unspecified Adult Solid Tumor, Protocol Specific1
3RecruitingTreatmentAcute Lymphoblastic Leukemia, Pediatric1
3RecruitingTreatmentAnaplastic Astrocytoma of Brain / Glioblastoma Multiforme of Brain1
4CompletedTreatmentDiaper Rash1
4CompletedTreatmentHyperpigmentation1
4CompletedTreatmentMelasma1
4Enrolling by InvitationSupportive CareColectomy / Opioids Use / Postoperative pain / Surgery, Colorectal1
4Not Yet RecruitingTreatmentCaesarean Sections1
4RecruitingTreatmentCardiothoracic Surgery1
4TerminatedTreatmentAnalgesia / Aspiration / Pain NOS / Tibial Fractures1
Not AvailableCompletedPreventionPigmentation From Visible Light1
Not AvailableCompletedTreatmentFoot Dryness in Patients With NIDDM / Foot Transepidermal Water Loss in Patients in NIDDM1
Not AvailableNot Yet RecruitingNot AvailableHepatocellular,Carcinoma1
Not AvailableTerminatedTreatmentDiaper Rash1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
LotionTopical20 mg/1mL
StickTopical87 mg/1g
Aerosol, sprayTopical120 mg/1mL
Cream; kitTopical
LotionTopical144 mg/1mL
CreamTopical4.97 g/100mL
CreamTopical140 mg/1mL
CreamTopical12 mg/100mL
LotionTopical17 g/100g
CreamTopical5.5 g/100g
StickTopical5.5 g/100g
LotionTopical0.1365 mg/1mL
CreamTopical13.5 g/100g
LotionTopical22.5 g/100g
CreamTopical17.5 g/100g
StickTopical4.14 g/18.4g
KitTopical
PowderTopical9.1 g/100g
PowderTopical5 g/100g
LotionTopical20 g/100mL
LipstickTopical8 g/100g
EmulsionTopical10 g/100mL
PatchCutaneous; Topical; Transdermal
SprayTopical10 g/99g
LotionTopical15 g/100mL
CreamTopical21 g/100g
LotionTopical8.5 g/100g
CreamTopical200 mg/1mL
CreamTopical17.1 g/57g
CreamTopical10 g/10g
OintmentTopical130 g/1g
CreamTopical16.51 g/127g
CreamTopical23.8 g/85g
CreamTopical2.75 g/11g
OintmentTopical11.3 %
CreamTopical150 mg/1g
OintmentTopical16 g/100g
OintmentTopical16 mL/100mL
CreamTopical16 g/100g
CreamTopical120 mg/1mL
LotionTopical12 g/100mL
LotionTopical14 g/100mL
Kit10 g/100mL
CreamTopical18.75 g/100mL
StickTopical8 g/100g
StickTopical8.0 g/100g
LotionTopical20.0 g/100mL
StickTopical22.5 g/100g
OintmentTopical18.75 mL/100mL
CreamTopical22.5 g/100mL
LotionTopical10.55 g/100mL
CreamTopical10 g/100mL
CreamTopical10.0 g/100mL
CreamTopical.113 g/1g
CreamTopical0.113 g/1g
PoulticeTopical
PowderTopical20 g/100g
CreamTopical12 %
CreamTopical5.0016 g/100mL
CreamTopical1.92 g/100mL
StickTopical15.4 g/100g
EmulsionTopical19 g/100mL
LipstickTopical8.05 g/100g
LotionTopical140 mg/1mL
LotionTopical200 mg/1mL
CreamTopical17 mL/100mL
OintmentTopical0.10 g/1g
LotionTopical19.7 g/100mL
LotionTopical18 g/100mL
CreamTopical20 g/100mL
Kit19 g/100mL
OintmentTopical0.15 g/1g
OintmentTopical17.75 g/71g
CreamTopical16 g/113g
CreamTopical40 g/113g
LotionTopical0.6375 g/4.25g
LiquidTopical10 g/100mL
SprayTopical4 g/100g
PasteTopical45.2 g/113g
CreamTopical14.69 g/113g
CreamTopical12 g/100g
CreamTopical16 g/70mL
CreamTopical120 mg/1g
OintmentTopical.2 g/1g
SolutionTopical
CreamTopical175 mg/1mL
LotionTopical134.5 mg/1mL
CreamTopical20 mg/100mL
LotionTopical120 mg/1mL
EmulsionTopical
CreamTopical185 mg/1g
OintmentTopical0.4 g/1g
LotionTopical200 mg/1g
OintmentTopical13.0 kg/100kg
CreamTopical20 %
PasteTopical20 %
CreamTopical.013 g/1g
LotionTopical66 mg/1mL
LotionTopical10 g/100g
LotionTopical17.5 g/100g
CreamTopical12.5 g/100g
CreamTopical.135 mg/1g
CreamTopical0.9 g/100mL
CreamTopical5.0 g/100g
PasteTopical200 mg/1g
LotionTopical95 mg/1mL
CreamTopical95 mg/1mL
CreamTopical152.5 mg/1g
CreamTopical15.25 g/100g
CreamTopical12 g/100mL
PasteTopical400 mg/1g
CreamTopical130 mg/1g
OintmentTopical132.1 mg/1g
OintmentTopical40 g/100g
OintmentTopical21.76 g/100g
CreamTopical0.1 g/1g
CreamTopical0.113 kg/1g
CreamTopical0.40 g/1g
OintmentTopical.1 g/1g
OintmentTopical0.2 g/1g
CreamTopical19 g/100mL
OintmentTopical14 g/100g
CreamTopical4.9 g/100g
OintmentTopical12 %
CreamTopical96 mg/1g
OintmentTopical100 mg/1g
SprayTopical10 g/100g
CreamTopical0.01248 g/1g
LiquidCutaneous
GelTopical100 mg/1mL
OintmentTopical65 mg/1g
OintmentTopical10 g/100g
LotionTopical20 mg/100mL
OintmentTopical250 mg/1g
OintmentTopical19 g/100g
OintmentTopical21 g/100g
PowderTopical15.004 g/100g
LotionTopical22 g/100g
CreamTopical13.8 g/100mL
CreamTopical25 g/100mL
CreamTopical75 g/1000g
Aerosol, sprayTopical
CreamTopical60 g/1000g
CreamTopical225 mg/100mL
CreamTopical59.02 g/454g
CreamTopical181.6 g/454g
CreamTopical20 mL/100mL
EmulsionTopical1.1 g/10g
LotionTopical100 mg/1mL
CreamTopical163.2 mg/1mL
CreamTopical177 mg/1mL
LotionTopical13.6 g/100mL
CreamTopical168 mg/1mL
CreamTopical101 mg/1mL
LotionTopical19 g/100g
StickTopical
PatchTopical
LiquidTopical13.8 g/100mL
PatchTopical8.3 g/100g
CreamTopical25 mL/100mL
CreamTopical0.125 mL/1mL
LiquidTopical0.65 mg/130mL
PasteTopical200 mg/1mL
OintmentTopical18 mg/1g
CreamTopical190 mg/1g
PowderTopical
PowderTopical0.02 g/1g
StickCutaneous
CreamTopical0.10 g/1g
CreamTopical13 mg/1g
PasteOral400 mg/1g
LiquidTopical160 mg/1mL
LotionTopical25 g/100g
OintmentRectal
SuppositoryRectal
OintmentRectal50 mg/1g
OintmentTopical150 mg
LotionTopical19 g/100mL
LotionTopical9.3 g/100mL
Spray, suspensionTopical12 g/100mL
CreamTopical0.03 g/1mL
PowderTopical0.0192 g/1g
PowderTopical0.0291 g/1g
LotionTopical13.5 g/100g
PasteTopical25 %
Tablet, coatedOral
CreamTopical14.5 mg/1mL
PowderTopical24.5 g/100g
LiquidTopical1.6 g/100g
CreamTopical0.07 g/1g
CreamTopical0.0192 g/1g
LiquidTopical0.02 g/1g
CreamTopical13.0 %
PowderTopical10 %
Kit130 mg/1g
PowderTopical100 mg/1g
Cream, augmentedTopical
OintmentTopical10 mL/100mL
OintmentTopical250 g/1000g
LotionTopical15 g/100g
CreamTopical16.96 mg/80mL
PasteTopical
LotionTopical0.0157 g/1mL
LotionTopical0.48 g/30mL
LiquidTopical.016 g/1mL
LiquidTopical0.016 g/1mL
Lotion / shampooTopical
CreamTopical4 g/10g
CreamTopical9.45 mg/1mL
CreamTopical170 mg/1g
OintmentTopical113.6 g/284g
CreamTopical3.8 g/100g
OintmentTopical3.8 g/100g
LotionTopical30 g/150g
StickTopical10.5 g/100g
StickTopical8.55 g/100g
LipstickTopical105 mg/1mL
LipstickTopical
LotionTopical7.9 mg/100mL
CreamTopical14 g/100mL
OintmentTopical18 g/100g
CreamTopical0.0098 g/1g
CreamTopical400 mg/1g
OintmentRectal; Topical
SuppositoryRectal1.7 g/1
CreamTopical50 mg/1mL
DressingTopical19.8 g/165g
DressingTopical24.6 g/205g
OintmentTopical
CreamTopical6.8 g/100mL
OintmentTopical96 mg/1g
OintmentTopical9.6 g/100g
CreamTopical1.8 g/100g
PasteTopical40 g/100g
PlasterTopical28.3 %
LotionTopical0.25 mg/1mg
CreamTopical50.0 mg/1mL
StickTopical17 g/100g
CreamTopical24 mg/1g
CreamCutaneous3.5 mL/50mL
LotionTopical175 mg/1mL
CreamTopical105 mg/1mL
Tablet, chewableOral
CreamTopical9.9 g/100g
LotionTopical8.3 g/83g
LotionTopical5.5 g/55g
CreamTopical13 g/100g
PowderCutaneous
CreamTopical189 mg/1mL
CreamTopical7.85 g/50mL
LotionTopical24 g/68mL
CreamTopical24.96 g/100g
LotionTopical22 g/100mL
OintmentTopical8.8 g/88mL
LotionCutaneous
LotionTopical182.4 mg/1mL
LotionTopical216 mg/1mL
LotionTopical8.5 g/100mL
Kit100 mg/1
CreamTopical.12 mL/1mL
Kit; lotionTopical
LotionTopical185 mg/1g
Kit175 mg/1mL
LotionTopical
SuspensionTopical
StickTopical5.7 g/100g
CreamTopical17 g/100mL
LipstickTopical10 g/100g
CreamTopical114 mg/1mL
OintmentTopical0.08 g/56g
CreamTopical250 mg/1g
PasteTopical180 mg
PasteTopical25 g/100g
LotionTopical13.0 %
CreamTopical2.4 g/0.259mL
LotionTopical0.13 mg/2.5mL
CreamCutaneous
CapsuleOral
CreamTopical20 g/100g
OintmentTopical20 g/100g
Tablet, film coatedOral
GelTopical110 mg/1mL
CreamTopical5 g/1mL
SprayTopical
CreamTopical7.5 g/100g
LotionTopical1 g/5g
LiquidTopical0.0098 g/1mL
LiquidTopical76 mg/1mL
SalveTopical20 g/100g
CreamTopical15 g/100g
LotionTopical7.5 mL/100mL
CreamTopical1.6 g/20mL
CreamTopical4.9 g/100mL
OintmentTopical.20 g/1g
CreamTopical18.5 g/100g
CreamTopical230 mg/1mL
CreamTopical227.5 mg/1g
StickTopical227.5 mg/1g
TabletOral
KitOral
Kit4.95 mg/3g
LotionTopical49.5 mg/1mL
Kit49.5 mg/1mL
CreamTopical4.45 g/100g
CreamTopical49 mg/1g
DressingTopical
Capsule, liquid filledOral
PasteTopical20 g/100g
DressingTopical25 g/1
CreamTopical13 g/100mL
CreamTopical0.0686 mg/1g
OintmentTopical400 mg/1g
CreamTopical.9 mL/30mL
StickTopical35 mg/1g
CreamTopical8 g/90mL
CreamTopical0.26 g/1.54g
PlasterTopical
LotionTopical0.75 g/5mL
PowderTopical18 g/100g
Capsule, gelatin coatedOral
CreamTopical306.1 mg/1g
CreamTopical100 mg/1g
LotionTopical160 mg/1mL
CreamTopical2 kg
Aerosol, foamTopical140 mg/1mL
PowderTopical12 mg/0.1g
PowderTopical12 mg/100mg
CreamTopical21 g/100mL
CreamTopical40 g/100g
PowderTopical5 %
GelTopical20 g/100g
LotionTopical19 g/142g
LotionTopical25 g/142g
PasteTopical12.5 g/100g
LipstickTopical0.462 g/4.62g
LotionTopical23.7 g/118.294g
LiquidTopical
OintmentTopical0.085 g/1g
OintmentTopical55 mg/1g
LipstickTopical65 mg/1g
CreamTopical.0702 mg/1g
CreamTopical200 mg/1g
Aerosol, foamTopical
CreamTopical223 mg/1g
CreamTopical10.8 g/96g
GelTopical
CreamTopical2.94 g/28g
CreamTopical.15 g/1g
LotionTopical20 g/100g
CreamTopical186 mg/1mL
LotionTopical220 mg/1mL
LiquidTopical8.82 g/90mL
SpongeTopical
SprayTopical140 mg/1mL
StickTopical80 mg/1g
StickTopical192 mg/1g
CreamTopical220 mg/1g
CreamTopical
SprayTopical12 g/100mL
StickTopical17 g/100mL
GelTopical186 mg/1mL
CreamTopical190 mg/1mL
CreamTopical170 mg/1mL
CreamTopical43.4 g/177mL
CreamTopical28.9 g/118mL
CreamTopical25 g/100g
LiquidTopical50 mg/1mL
LotionTopical1 g/1g
LotionTopical4.5 g/30mL
LotionTopical12.9 mL/52mL
LotionTopical1.24 mL/5mL
LotionTopical32.3 mL/130mL
StickTopical20 g/100g
LipstickTopical18 g/100g
CreamTopical882.7 mg/9.1g
StickTopical24.5 g/100g
LotionTopical30 mg/1mL
OintmentTopical9 g/75g
SalveTopical
CreamTopical15 g/100mL
LotionTopical10 g/100mL
CreamTopical100 mg/1mL
StickTopical200 ug/1g
CreamTopical176.7 mg/1g
CreamTopical10 g/100g
CreamTopical0.12 g/1g
CreamTopical0.2 g/1g
PowderTopical9.6 g/150mL
SprayTopical25 g/100g
CreamTopical1.15 g/40mL
StickTopical22 g/100g
LotionTopical22.5 g/100mL
CreamTopical10 %
PasteTopical12.8 g/100g
LotionTopical20 mL/100mL
SprayTopical24 mL/120mL
CreamTopical10 mL/50mL
CreamTopical0.135 mg/1g
PasteTopical5 mg/1cm2
CreamTopical.07 g/1g
OintmentTopical13.0 g/100g
OintmentTopical40.0 g/100g
AerosolTopical
LotionTopical6.87 g/34.35g
CreamTopical6.00 g/50mL
PasteTopical125 mg/1g
PowderTopical0.69 g/3g
Kit
PowderTopical2 g/100g
OintmentTopical0.40 g/1g
LotionTopical146 mg/1mL
CreamTopical14 g/100g
ClothTopical20 g/100g
LotionTopical190 mg/1mL
StickTopical7.6 g/100g
StickTopical6.5 g/100g
LotionTopical210 mg/1mL
CreamTopical1.96 g/100g
CreamTopical22 g/100g
LotionTopical8 g/100g
CreamTopical15 %
OintmentTopical15 %
CreamTopical0.2 kg/1kg
OintmentTopical1.8 g/100g
OintmentTopical160 mg/1g
OintmentTopical200 mg/1g
PasteTopical532 mg/1g
CreamTopical15 g
OintmentTopical20 g
OintmentTopical20 %
CreamTopical186 mg/1g
OintmentTopical40 %
Prices
Not Available
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US8147852No2008-03-302028-03-30Us

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-0.2ChemAxon
pKa (Strongest Basic)-5.7ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area17.07 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity1.44 m3·mol-1ChemAxon
Polarizability3 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of inorganic compounds known as transition metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen is a transition metal.
Kingdom
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Class
Transition metal organides
Sub Class
Transition metal oxides
Direct Parent
Transition metal oxides
Alternative Parents
Inorganic salts / Inorganic oxides
Substituents
Transition metal oxide / Inorganic oxide / Inorganic salt
Molecular Framework
Not Available
External Descriptors
zinc molecular entity (CHEBI:36560)

Drug created on November 17, 2015 10:38 / Updated on October 21, 2018 20:37