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Displaying drugs 76 - 100 of 238 in total
Dequalinium
Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Categories: … Quinoline Derivatives …
Delafloxacin
Delafloxacin is a fluoroquinolone antibiotic which has been used in trials studying the treatment and basic science of Gonorrhea, Hepatic Impairment, Bacterial Skin Diseases, Skin Structure Infections, and Community Acquired Pneumonia, among others. It was approved in June 2017 under the trade name Baxdela for use in the treatment of...
Approved
Investigational
Moxifloxacin
Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Mesalazine
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical...
Approved
Levomenthol
Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Mixtures name: … Axpain Methyl Salicylate Gel ... Axpain Methyl Salicylate Cream …
Menthol
Approved
Matched Mixtures name: … Menthol and Methyl Salicylate ... Menthol and Methyl Salicylate ... Eucalyptol, menthol, methyl salicylate, thymol …
Clioquinol
Clioquinol was withdrawn in 1983 due to neurotoxicity.
Approved
Vet approved
Withdrawn
Matched Categories: … Quinoline Derivatives …
Ivacaftor
Ivacaftor (also known as Kalydeco or VX-770) is a drug used for the management of Cystic Fibrosis (CF). It is manufactured and distributed by Vertex Pharmaceuticals. It was approved by the Food and Drug Administration on January 31, 2012 , and by Health Canada in late 2012. Ivacaftor is administered...
Approved
Cabergoline
Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Approved
Pyrvinium
Pyrvinium is an anthelmintic effective for pinworms. Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate. Pyrvinum's anti-cancer properties are currently under investigation.
Approved
Dihydroergocornine
Dihydroergocornine is one of the dihydrogenated ergot compounds that present very large hypotensive effects. It is an artificial derivative of the crude extract of ergot and later purified, ergocornine. The formation of dihydroergocornine implies the hydrogenation of the double bonds in the lysergic acid. Dihydroergocornine presents a formula of 9,10...
Approved
Bedaquiline
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Cabozantinib
Cabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. It was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer. In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal...
Approved
Investigational
Topotecan
An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Montelukast
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Antrafenine
Antrafenine is a piperazine derivative drug that acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen. It is not widely used as it has largely been replaced by newer drugs.
Approved
Dihydroergocristine
Dihydroergocristine is part of the ergoloid mixture products. It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline. To know more about ergoloid mixtures, please visit DB01049.
Approved
Experimental
Aminosalicylic acid
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Magnesium salicylate
Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. It is available in several over-the-counter (OTC) formulations. Though the recommended doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium salicylate tetrahydrate, equivalent to 934.4 mg...
Experimental
Matched Synonyms: … Magnesium salicylate ... Magnesium salicylate anhydrous …
Matched Name: … Magnesium salicylate …
Matched Description: … Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate ... tetrahydrate, equivalent to 934.4 mg anhydrous magnesium salicylate), effective pain relief is often ... doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium salicylate …
Matched Salts name: … Magnesium salicylate tetrahydrate …
Matched Name: … Magnesium salicylate …
Matched Description: … Magnesium salicylate is a non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate ... tetrahydrate, equivalent to 934.4 mg anhydrous magnesium salicylate), effective pain relief is often ... doseage is 1160 mg every six hours, per package directions of the Doan's OTC brand (580 mg magnesium salicylate …
Matched Salts name: … Magnesium salicylate tetrahydrate …
Imidazole salicylate
Experimental
Matched Synonyms: … Imidazole salicylate …
Matched Name: … Imidazole salicylate …
Matched Categories: … imidazole salicylate …
Matched Name: … Imidazole salicylate …
Matched Categories: … imidazole salicylate …
4-(3-Pyridin-2-Yl-1h-Pyrazol-4-Yl)Quinoline
Experimental
Matched Name: … 4-(3-Pyridin-2-Yl-1h-Pyrazol-4-Yl)Quinoline …
Matched Iupac: … 4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline …
Matched Iupac: … 4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline …
8-Hydroxy-4-(1-Hydroxyethyl)Quinoline-2-Carboxylic Acid
Experimental
Matched Name: … 8-Hydroxy-4-(1-Hydroxyethyl)Quinoline-2-Carboxylic Acid …
Displaying drugs 76 - 100 of 238 in total