Displaying drugs 101 - 125 of 15095 in total
Azelastine
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Synonyms: … 4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone …
Matched Iupac: … 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one …
Matched Description: … marketed under the trade name Dymista™, which is indicated for the symptomatic treatment of seasonal ... allergic rhinitis in patients 6 years of age and older. ... between enantiomers, and was first granted FDA approval in 1996. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … AZEP NASAL SPRAY 1 mg/ml ... Azedil 1 mg/ml Nasenspray ... Azelastin POS 1 mg/ml Nasenspray, Lösung …
Matched Iupac: … 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one …
Matched Description: … marketed under the trade name Dymista™, which is indicated for the symptomatic treatment of seasonal ... allergic rhinitis in patients 6 years of age and older. ... between enantiomers, and was first granted FDA approval in 1996. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … AZEP NASAL SPRAY 1 mg/ml ... Azedil 1 mg/ml Nasenspray ... Azelastin POS 1 mg/ml Nasenspray, Lösung …
Ibrutinib
Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Synonyms: … 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Iupac: … 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Description: … 2023, the drug manufacturer withdrew the accelerated approvals for ibrutinib in the US. ... [L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November ... for the treatment of mantle cell lymphoma (MCL) under accelerated approval;[L12228] however, in April …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Description: … 2023, the drug manufacturer withdrew the accelerated approvals for ibrutinib in the US. ... [L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November ... for the treatment of mantle cell lymphoma (MCL) under accelerated approval;[L12228] however, in April …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Cyclacillin
A cyclohexylamido analog of penicillanic acid.
Approved
Matched Synonyms: … -2-carboxylic acid ... (1-aminocyclohexyl)penicillin ... (2S,5R,6R)-6-{[(1-aminocyclohexyl)carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Matched Iupac: … (2S,5R,6R)-6-(1-aminocyclohexaneamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2S,5R,6R)-6-(1-aminocyclohexaneamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Sulfaphenazole
Sulfaphenazole is a sulfonamide antibacterial.
Approved
Matched Synonyms: … 3-(p-aminobenzenesulfonamido)-2-phenylpyrazole ... N(1)-(1-phenylpyrazol-5-yl)sulfanilamide ... 1-phenyl-5-sulfanilamidopyrazole …
Matched Iupac: … 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ciclopirox
Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.
Approved
Investigational
Matched Synonyms: … 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone …
Matched Iupac: … 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one …
Matched Description: … In particular, the agent is especially effective in treating Tinea versicolor. ... Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a …
Matched Salts cas: … 41621-49-2 …
Matched Mixtures name: … Ciclopirox Olamine 1% / Salicylic Acid 2% ... Ciclopirox 0.77% / Salicylic Acid 2% ... Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Loprox Crm 1% ... Loprox Cream 1% ... Loprox Lotion 1% …
Matched Iupac: … 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one …
Matched Description: … In particular, the agent is especially effective in treating Tinea versicolor. ... Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a …
Matched Salts cas: … 41621-49-2 …
Matched Mixtures name: … Ciclopirox Olamine 1% / Salicylic Acid 2% ... Ciclopirox 0.77% / Salicylic Acid 2% ... Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Loprox Crm 1% ... Loprox Cream 1% ... Loprox Lotion 1% …
Memantine
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Synonyms: … 1-Amino-3,5-dimethyladamantane ... 3,5-Dimethyl-1-adamantanamine ... 3,5-Dimethyl-1-aminoadamantane …
Matched Iupac: … 3,5-dimethyladamantan-1-amine …
Matched Description: … used in the management of Alzheimer's Disease (AD). ... Memantine blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability ... Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist …
Matched Salts cas: … 41100-52-1 …
Matched Iupac: … 3,5-dimethyladamantan-1-amine …
Matched Description: … used in the management of Alzheimer's Disease (AD). ... Memantine blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability ... Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist …
Matched Salts cas: … 41100-52-1 …
Ertapenem
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem ... -7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl …
Matched Iupac: … ]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. ... Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. …
Matched Salts cas: … 153773-82-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ERTAGRAM® 1 G ... INVANZ 1 G IM/IV ENEJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET ... INVANZ FOR INJECTION 1 g/vial …
Matched Iupac: … ]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. ... Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. …
Matched Salts cas: … 153773-82-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ERTAGRAM® 1 G ... INVANZ 1 G IM/IV ENEJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET ... INVANZ FOR INJECTION 1 g/vial …
Betaxolol
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Synonyms: … 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol ... 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol …
Matched Iupac: … 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … A cardioselective beta-1-adrenergic antagonist with no partial agonist activity. …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Matched Iupac: … 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … A cardioselective beta-1-adrenergic antagonist with no partial agonist activity. …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Clemastine
An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Approved
Investigational
Matched International brands: … Tavist-1 ... Allerhist-1 …
Matched Synonyms: … (+)-(2R)-2-(2-(((R)-p-chloro-α-methyl-α-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine ... (+)-(2R)-2-[2-[[(R)-p-chloro-α-methyl-α-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine …
Matched Iupac: … (2R)-2-{2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine …
Matched Description: … An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … TAVEGYL 1 MG TABLET, 20 ADET ... CLEMAXCLIN® 2 MG/2ML SOLUCIÓN INYECTABLE. …
Matched Synonyms: … (+)-(2R)-2-(2-(((R)-p-chloro-α-methyl-α-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine ... (+)-(2R)-2-[2-[[(R)-p-chloro-α-methyl-α-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine …
Matched Iupac: … (2R)-2-{2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine …
Matched Description: … An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … TAVEGYL 1 MG TABLET, 20 ADET ... CLEMAXCLIN® 2 MG/2ML SOLUCIÓN INYECTABLE. …
Dutasteride
Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal...
Approved
Investigational
Matched Synonyms: … α,α,α,α',α',α'-hexafluoro-3-oxo-4-aza-5α-androst-1-ene-17β-carboxy-2',5'-xylidide ... (5α,17β)-N-(2,5-bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide …
Matched Iupac: … (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-bis(trifluoromethyl)phenyl]-4a,6a-dimethyl-2-oxo-1H,2H,4aH,4bH,5H …
Matched Description: … hormonal mediator that plays a role in the development and enlargement of the prostate gland. ... [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary ... (BPH) in men as monotherapy or in combination with the α-adrenergic antagonist [tamsulosin] to enhance …
Matched Categories: … Drugs Used in Benign Prostatic Hypertrophy ... 5-alpha Reductase Inhibitors ... Adrenergic alpha-Antagonists …
Matched Iupac: … (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-bis(trifluoromethyl)phenyl]-4a,6a-dimethyl-2-oxo-1H,2H,4aH,4bH,5H …
Matched Description: … hormonal mediator that plays a role in the development and enlargement of the prostate gland. ... [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary ... (BPH) in men as monotherapy or in combination with the α-adrenergic antagonist [tamsulosin] to enhance …
Matched Categories: … Drugs Used in Benign Prostatic Hypertrophy ... 5-alpha Reductase Inhibitors ... Adrenergic alpha-Antagonists …
Tapentadol
Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596]
Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Synonyms: … 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol ... PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)- …
Matched Iupac: … 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol …
Matched Description: … [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited ... The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011. ... [A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. …
Matched Iupac: … 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol …
Matched Description: … [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited ... The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011. ... [A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. …
Ethchlorvynol
Ethchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Approved
Illicit
Withdrawn
Matched Synonyms: … 1-chloro-3-ethyl-1-penten-4-yn-3-ol ... 1-Chloro-3-ethyl-pent-1-en-4-yn-3-ol ... 3-(β-chlorovinyl)-1-pentyn-3-ol …
Matched Iupac: … (1E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol …
Matched Iupac: … (1E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol …
Thiethylperazine
A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
Approved
Withdrawn
Matched Synonyms: … 2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Iupac: … 2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Description: … A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with …
Matched Salts cas: … 52239-63-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Description: … A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with …
Matched Salts cas: … 52239-63-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Iptacopan
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … that normally anchor 2 membrane proteins, CD55 and CD59, that protect blood cells against the alternative ... of the PIGA gene. ... [A262581] This is of particular importance to PNH, where one of the disease hallmarks is the mutation …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … that normally anchor 2 membrane proteins, CD55 and CD59, that protect blood cells against the alternative ... of the PIGA gene. ... [A262581] This is of particular importance to PNH, where one of the disease hallmarks is the mutation …
Tavaborole
Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis...
Approved
Investigational
Matched Synonyms: … 5-Fluoro-2,1-benzoxaborol-1(3H)-ol ... 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole …
Matched Iupac: … 5-fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol …
Matched Description: … Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, ... a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes ... Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the …
Matched Iupac: … 5-fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol …
Matched Description: … Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, ... a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes ... Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the …
Doxercalciferol
Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment...
Approved
Matched Synonyms: … 1-Hydroxyvitamin D2 ... 1-Hydroxyergocalciferol …
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden …
Matched Description: … kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients ... Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic ... Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form …
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden …
Matched Description: … kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients ... Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic ... Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form …
Enmetazobactam
Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Synonyms: … 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept ... -2-carboxylate ... (2s,3s,5r)-3-methyl-3-((3-methyltriazol-3-ium-1-yl)methyl)-4,4,7-trioxo-4^6-thia-1-azabicyclo(3.2.0)heptane …
Matched Iupac: … 1-{[(2S,3S,5R)-2-carboxylato-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptan-3-yl]methyl …
Matched Description: … penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in ... [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA ... the treatment of serious infections. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-{[(2S,3S,5R)-2-carboxylato-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptan-3-yl]methyl …
Matched Description: … penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in ... [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA ... the treatment of serious infections. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Meglumine
Approved
Matched Synonyms: … 1-deoxy-1-methylaminosorbitol …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Tolazamide
A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Synonyms: … 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea ... 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Matched Categories: … Drugs Used in Diabetes …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Matched Categories: … Drugs Used in Diabetes …
Mucor circinelloides f. circinelloides
Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Mucor circinelloides f. circinelloides whole …
Matched Description: … Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing. …
Matched Description: … Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing. …
Midodrine
An ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Approved
Matched Synonyms: … 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol ... (±)-2-amino-N-(β-hydroxy-2,5-dimethoxyphenethyl)acetamide ... 2-Amino-N-(2,5-dimethoxy-beta-hydroxyphenethyl)acetamide …
Matched Iupac: … 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide …
Matched Description: … It is used as a vasoconstrictor agent in the treatment of hypotension. ... An ethanolamine derivative that is an adrenergic alpha agonist. …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-Agonists …
Matched Products: … GUTRON TROPFEN 1% ... Gutron 1 % - Tropfen …
Matched Iupac: … 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide …
Matched Description: … It is used as a vasoconstrictor agent in the treatment of hypotension. ... An ethanolamine derivative that is an adrenergic alpha agonist. …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-Agonists …
Matched Products: … GUTRON TROPFEN 1% ... Gutron 1 % - Tropfen …
Povidone
Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Synonyms: … 1-vinyl-2-pyrrolidinone polymer ... 1-ethenyl-2-pyrrolidinone homopolymer …
Matched Description: … in a few clinical studies that the application of the compound in wounds was associated with impaired ... When in complex with iodine, [DB06812] displays antiseptic properties where the iodine, a bactericidal ... [DB06812] can be found in over-the-counter topical solutions, ointment, pessaries, liquid soaps and surgical …
Matched Mixtures name: … Murine Tears 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Matched Products: … VIDISEPT 2% …
Matched Description: … in a few clinical studies that the application of the compound in wounds was associated with impaired ... When in complex with iodine, [DB06812] displays antiseptic properties where the iodine, a bactericidal ... [DB06812] can be found in over-the-counter topical solutions, ointment, pessaries, liquid soaps and surgical …
Matched Mixtures name: … Murine Tears 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Matched Products: … VIDISEPT 2% …
Terbinafine
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Synonyms: … (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine ... (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine …
Matched Iupac: … [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine …
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues ... [A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene ... monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall synthesis …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% ... Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% ... M-FURO MANT % 0.1 + % 1 KREM, 20G …
Matched Products: … ERBINOL % 1 KREM ,1 TÜP ... LAMISIL 1% ... FUNGIFEET 1% LOCION (TERBINAFINA CLORHIDRATO 1%) …
Matched Iupac: … [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine …
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues ... [A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene ... monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall synthesis …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% ... Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% ... M-FURO MANT % 0.1 + % 1 KREM, 20G …
Matched Products: … ERBINOL % 1 KREM ,1 TÜP ... LAMISIL 1% ... FUNGIFEET 1% LOCION (TERBINAFINA CLORHIDRATO 1%) …
Susoctocog alfa
Intravenous susoctocog alfa is a recombinant, B-domain deleted, porcine sequence antihaemophilic factor VIII (FVIII) product that has recently been approved for the treatment of bleeding episodes in adults with acquired haemophilia A (AHA). AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the...
Approved
Investigational
Matched Synonyms: … RECOMBINANT DNA DERIVED B-DOMAIN DELETED PORCINE BLOODCOAGULATION FACTOR VIII ANALOGUE, PRODUCED IN BHK21 …
Matched Description: … In a global, prospective, controlled, multi-center Phase 2/3 open-label clinical trial, all patients ... Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the activated …
Matched Description: … In a global, prospective, controlled, multi-center Phase 2/3 open-label clinical trial, all patients ... Susoctocog alfa was approved by the FDA in October 2014 and is marketed under the brand name Obizur for ... AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the activated …
Flunarizine
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Synonyms: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Iupac: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Description: … and peripheral origin, and as an adjuvant in the therapy of epilepsy. ... It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Description: … and peripheral origin, and as an adjuvant in the therapy of epilepsy. ... It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 101 - 125 of 15095 in total