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Displaying drugs 101 - 125 of 161 in total

Dexmedetomidine

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Dexmedetomidine Hydrochloride in Sodium Chloride ... Dexmedetomidine Hydrochloride In 0.9% Sodium Chloride ... PRECEDEX™ IN 0.9% SODIUM CHLORIDE INJECTION 4MCG/ML …

Vasopressin

Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Description: … renal fluid reuptake by acting through V1 and V2 cellular receptors. ... [A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and ... hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and …
Matched Categories: … Vasopressin and Analogues ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Vasopressin in 0.9% Sodium Chloride …

Dextran

Dextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links. The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units....
Approved
Investigational
Vet approved
Matched Description: … Chloride Injection. ... preparation of low molecular weight dextran (average mol. wt. 40,000) in 5% Dextrose Injection or 0.9% Sodium ... The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and …
Matched Mixtures name: … Lmd 10% In 0.9% Sodium Chloride ... Gentran 40 10% Sodium Chloride 0.9% Inj ... Gentran-70 6% & Sodium Chloride 0.9% Inj …
Matched Salts name: … Dextran sulfate sodium ... Dextran sulfate sodium (MW 5000) ... Dextran sulfate sodium (MW 9500) ... Dextran sulfate sodium (MW 54000) ... Dextran sulfate sodium (MW 520000) …
Matched Categories: … Blood and Related Products ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Matched Products: … LMD in Sodium Chloride …

Dextrose, unspecified form

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Description: … through aerobic or anaerobic respiration and fermentation. ... Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and ... L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. …
Matched Mixtures name: … Potassium Chloride in Dextrose and Sodium Chloride ... Potassium Chloride in Dextrose and Sodium Chloride ... Potassium Chloride in Dextrose and Sodium Chloride …

Lactic acid

A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Description: … (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste ... It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the …
Matched Mixtures name: … Potassium Chloride and Dextrose ... Potassium Chloride in Lactated Ringers and Dextrose ... Potassium Chloride in Lactated Ringers and Dextrose …
Matched Salts name: … Sodium lactate …
Matched Categories: … Basic Ointments and Protectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Sodium Lactate …

Meropenem

Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Salts name: … Meropenem sodium …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP …

Bendroflumethiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... bendroflumethiazide and potassium ... bendroflumethiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... Genito Urinary System and Sex Hormones …

Benzthiazide

Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Description: … Thiazides also cause loss of potassium and an increase in serum uric acid. ... Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in ... Benzthiazide is used to treat hypertension and edema. …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Hydroflumethiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)
Approved
Investigational
Withdrawn
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... hydroflumethiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Diclofenac

Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... PGs contribute to inflammation and pain signalling. ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). …
Matched Mixtures name: … Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol ... Diclofenac Sodium and Misoprostol …
Matched Salts name: … Diclofenac sodium ... Diclofenac potassium …
Matched Categories: … diclofenac and antiinfectives ... Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Arthritis Pain Reliever ... Diclofenac Potassium ... DICLOFENAC POTASSIUM …

Furosemide

Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... both pediatric and adult patients. ... In addition to oral formulations, the solution for intravenous and intramuscular administration is also …
Matched Salts name: … Furosemide sodium …
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors ... furosemide and potassium ... furosemide and potassium-sparing agents ... High-Ceiling Diuretics and Potassium-Sparing Agents ... Non Potassium Sparing Diuretics …

Gentamicin

Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment...
Approved
Vet approved
Matched Description: … Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea ... is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and ... [A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but …
Matched Mixtures name: … Gentamicin Sulfate In 0.9% Sodium Chloride Injection ... Garasone Ophthalmic and Otic Solution …
Matched Categories: … Ophthalmological and Otological Preparations …
Matched Products: … Gentamicin Sulfate In Sodium Chloride ... Gentamicin Sulfate in Sodium Chloride …

Chromium Cr-51

Chromium Cr-51 is an isotope of chromium that has been used as a radioactive label for decades. It is used as a diagnostic radiopharmaceutical agent in nephrology to determine glomerular filtration rate,[A249765,A249770] and in hematology to determine red blood cell volume or mass, study the red blood cell survival time...
Approved
Matched Description: … in hematology to determine red blood cell volume or mass, study the red blood cell survival time and ... diagnostic radiopharmaceutical agent in nephrology to determine glomerular filtration rate,[A249765,A249770] and …
Matched Salts name: … Chromium Cr-51 chloride …
Matched Products: … Sodium Chromate 51 …

Butabarbital

Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Description: … [A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Butabarbital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Butisol Sodium ... Butisol Sodium Tab 30mg ... Butisol Sodium Tab 15mg …

Salmon calcitonin

Synthetic peptide, 32 residues long formulated as a nasal spray.
Approved
Investigational
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Parathyroid Hormones and Analogues ... Calcium-Regulating Hormones and Agents ... Parathyroid and Antiparathyroid Agents …

Piretanide

Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Approved
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Amobarbital

A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Approved
Illicit
Matched Description: … A barbiturate with hypnotic and sedative properties (but not antianxiety). ... Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with …
Matched Salts name: … Amobarbital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Amytal Sodium ... Amytal Sodium 500mg ... Amytal Sodium Cap 60mg …

Acetazolamide

One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched Description: … gradient, increased chloride current, and increased inhibition. ... (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) ... due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride …
Matched Salts name: … Acetazolamide sodium …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Chlorthalidone

Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule...
Approved
Matched Description: … Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management ... effect is under debate, however, it is thought that increased diuresis results in decreased plasma and ... Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through …
Matched Mixtures name: … Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... chlortalidone and potassium ... chlortalidone and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... Non Potassium Sparing Diuretics …

Amiloride

A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with...
Approved
Matched Description: … Negative potential reduces secretion of potassium and hydrogen ions. ... A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. ... Amiloride is used in conjunction with diuretics to spare potassium loss. …
Matched Mixtures name: … Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide …
Matched Categories: … Potassium-Sparing Diuretics ... Sodium Channel Blockers ... Epithelial Sodium Channel Blockers …

Triamterene

Triamterene (2,4,7-triamino-6-phenylpteridine) is a potassium-sparing diuretic that is used in the management of hypertension. It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion in the distal part of the nephron in the kidneys by working on the lumenal side. Since it acts on...
Approved
Matched Description: … It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion ... is approved for use with other diuretics to enhance diuretic and potassium-sparing effects. ... [A177985] Since it acts on the distal nephron where only a small fraction of sodium ion reabsorption …
Matched Mixtures name: … Triamterene and Hydrochlorothiazide ... Triamterene and Hydrochlorothiazide ... Triamterene and Hydrochlorothiazide …
Matched Categories: … Potassium-Sparing Diuretics ... Sodium Channel Blockers ... Epithelial Sodium Channel Blockers …

Methazolamide

A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Approved
Matched Description: … A carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma. …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Desvenlafaxine

Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of venlafaxine. Like its parent drug, desvenlafaxine is also an antidepressant belonging to the class of serotonin-norepinephrine reuptake inhibitor (SNRI) class.[A261266,A261266] It was approved by the FDA in 2008 for the treatment of adults with major depressive disorder (MDD).[L6016,A261271] MDD is a highly...
Approved
Investigational
Matched Description: … a highly prevalent psychiatric disorder, with a lifetime prevalence estimate of 16% in the US alone and ... [A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …

Vancomycin

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Description: … kidneys and the inner ear. ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … Vancomycin Injection USP In 0.9% Sodium Chloride …

Indapamide

The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Description: … [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium ... The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor ... [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... Non Potassium Sparing Diuretics ... Genito Urinary System and Sex Hormones ... perindopril, amlodipine and indapamide ... rosuvastatin, perindopril and indapamide …
Displaying drugs 101 - 125 of 161 in total