Displaying drugs 201 - 225 of 14997 in total
Adenosine
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and ... not described in literature until the 1940s. ... The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were …
Matched Mixtures name: … Dr.Different VITALIFT A Eye and Neck ... Dr G deWrinkle REFORMER by EGF ... Dr G deWrinkle FORTIFIER by EGF …
Matched Products: … By Selected Reinforce Day Serum ... by Selected Recovering Almighty ... Advanced Snail 92 All in One Cream …
Matched Mixtures name: … Dr.Different VITALIFT A Eye and Neck ... Dr G deWrinkle REFORMER by EGF ... Dr G deWrinkle FORTIFIER by EGF …
Matched Products: … By Selected Reinforce Day Serum ... by Selected Recovering Almighty ... Advanced Snail 92 All in One Cream …
Zolmitriptan
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Synonyms: … 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one ... (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Iupac: … (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Description: … [A193797] Zolmitriptan was first approved by the FDA for sale by Zeneca Pharmaceuticals under the ... Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor ... It is currently available in both tablet and nasal spray forms.[L12978] …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Iupac: … (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Description: … [A193797] Zolmitriptan was first approved by the FDA for sale by Zeneca Pharmaceuticals under the ... Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor ... It is currently available in both tablet and nasal spray forms.[L12978] …
Matched Categories: … Monoamine Oxidase A Substrates …
Idarubicin
An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Synonyms: … 4-Demethoxydaunomycin ... 4-Demethoxydaunorubicin …
Matched Iupac: … (7S,9S)-9-acetyl-7-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,9,11-trihydroxy-5,7,8,9,10,12 …
Matched Categories: … Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … (7S,9S)-9-acetyl-7-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,9,11-trihydroxy-5,7,8,9,10,12 …
Matched Categories: … Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Benorilate
Approved
Matched Synonyms: … 4-acetamidophenyl salicylate acetate …
Matched Iupac: … 4-acetamidophenyl 2-(acetyloxy)benzoate …
Matched Iupac: … 4-acetamidophenyl 2-(acetyloxy)benzoate …
Netupitant
Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy including highly emetogenic chemotherapy. Netupitant is a neurokinin 1 receptor antagonist. The combination drug is marketed by Eisai...
Approved
Investigational
Matched Synonyms: … 2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl …
Matched Iupac: … 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin …
Matched Description: … Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron ... Netupitant is a neurokinin 1 receptor antagonist. ... The combination drug is marketed by Eisai Inc. and Helsinn Therapeutics (U.S.) …
Matched Iupac: … 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin …
Matched Description: … Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron ... Netupitant is a neurokinin 1 receptor antagonist. ... The combination drug is marketed by Eisai Inc. and Helsinn Therapeutics (U.S.) …
Sulfanilamide
Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Approved
Matched Synonyms: … 4-azanylbenzenesulfonamide ... 4-aminobenzene sulfonic acid amide …
Matched Iupac: … 4-aminobenzene-1-sulfonamide …
Matched Description: … Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline. …
Matched Iupac: … 4-aminobenzene-1-sulfonamide …
Matched Description: … Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline. …
Sulfacetamide
An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Synonyms: … N-Acetyl-4-aminobenzenesulfonamide ... N(1)-Acetyl-4-aminophenylsulfonamide …
Matched Iupac: … N-(4-aminobenzenesulfonyl)acetamide …
Matched Mixtures name: … Sodium Sulfacetamide and Sulfur Clarifying Wash in a Urea Vehicle ... SulfaCleanse 8/4 ... Sulfatol 10-4 Cleansing pads …
Matched Iupac: … N-(4-aminobenzenesulfonyl)acetamide …
Matched Mixtures name: … Sodium Sulfacetamide and Sulfur Clarifying Wash in a Urea Vehicle ... SulfaCleanse 8/4 ... Sulfatol 10-4 Cleansing pads …
Benzocaine
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Synonyms: … 4-aminobenzoic acid ethyl ester …
Matched Iupac: … ethyl 4-aminobenzoate …
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve ... [A231219] It is commonly used for local anesthesia in many over the counter products. ... [L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259] …
Matched Mixtures name: … Kank-A ... Ndc 72934- 5010-4 Benzocaine 20% / Lidocaine 8% / Tetracaine 4%. ... CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant …
Matched Products: … KANK-A ... BABY KANK-A ... Kank-A Mouth Pain …
Matched Iupac: … ethyl 4-aminobenzoate …
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve ... [A231219] It is commonly used for local anesthesia in many over the counter products. ... [L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259] …
Matched Mixtures name: … Kank-A ... Ndc 72934- 5010-4 Benzocaine 20% / Lidocaine 8% / Tetracaine 4%. ... CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant …
Matched Products: … KANK-A ... BABY KANK-A ... Kank-A Mouth Pain …
Tranexamic acid
Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Synonyms: … trans-4-(Aminomethyl)cyclohexanecarboxylic acid ... trans-4-aminomethylcyclohexane-1-carboxylic acid …
Matched Iupac: … (1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylic acid …
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. ... It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent …
Matched Products: … Tranexamic Acid In Sodium Chloride …
Matched Iupac: … (1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylic acid …
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. ... It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent …
Matched Products: … Tranexamic Acid In Sodium Chloride …
Benoxaprofen
The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Approved
Withdrawn
Matched Synonyms: … (1)-2-(4-Chlorophenyl)benzoxazole-5-propionic acid ... 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid ... 2-(4-Chlorophenyl)-alpha-methyl-5-benzoxazoleacetic acid …
Matched Iupac: … 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid …
Matched Iupac: … 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid …
Dipivefrin
Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Approved
Matched Synonyms: … 1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol ... (±)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate ... 4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate …
Matched Description: … Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. …
Matched Categories: … Sympathomimetics in Glaucoma Therapy …
Matched Description: … Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. …
Matched Categories: … Sympathomimetics in Glaucoma Therapy …
Brompheniramine
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Synonyms: … [3-(4-Bromo-phenyl)-3-pyridin-2-yl-propyl]-dimethyl-amine ... 3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine …
Matched Iupac: … [3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria. …
Matched Mixtures name: … Neo DM ... Altidec A …
Matched Products: … ฟรอสซี่ พิงค์ 4 ... BOMEX TABLET 4 mg …
Matched Iupac: … [3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria. …
Matched Mixtures name: … Neo DM ... Altidec A …
Matched Products: … ฟรอสซี่ พิงค์ 4 ... BOMEX TABLET 4 mg …
Pralatrexate
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … that is overexpressed in malignant cells and is upregulated by oncogenes. ... [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein ... [A246703] Pralatrexate was approved by the FDA on September 24, 2009. …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … that is overexpressed in malignant cells and is upregulated by oncogenes. ... [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein ... [A246703] Pralatrexate was approved by the FDA on September 24, 2009. …
Nitrendipine
Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Synonyms: … 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester …
Matched Iupac: … 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Nitrendipine is a calcium channel blocker with marked vasodilator action. ... It is an effective antihypertensive agent and differs from other calcium channel blockers in that it …
Matched Iupac: … 3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Nitrendipine is a calcium channel blocker with marked vasodilator action. ... It is an effective antihypertensive agent and differs from other calcium channel blockers in that it …
Nefazodone
Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb. Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) injury. Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with...
Approved
Withdrawn
Matched Synonyms: … 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one …
Matched Iupac: … 1-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol …
Matched Description: … Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb ... Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or ... Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) …
Matched Iupac: … 1-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol …
Matched Description: … Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb ... Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or ... Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) …
Hetacillin
Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative...
Approved
Vet approved
Withdrawn
Matched Synonyms: … (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... 6β-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]penicillanic acid …
Matched Iupac: … (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Description: … Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused ... by susceptible, usually gram-positive, organisms. ... Hetacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria …
Matched Salts cas: … 5321-32-4 …
Matched Iupac: … (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Description: … Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused ... by susceptible, usually gram-positive, organisms. ... Hetacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria …
Matched Salts cas: … 5321-32-4 …
Dicloxacillin
One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4- …
Matched Iupac: … (2S,5R,6R)-6-[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Products: … DICLOXACILINA 250 MG POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL …
Matched Iupac: … (2S,5R,6R)-6-[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Products: … DICLOXACILINA 250 MG POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL …
Fluphenazine
A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Synonyms: … 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine ... 4-(3-(-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol ... 4-(3-(2-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Description: … A phenothiazine used in the treatment of psychoses. …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Description: … A phenothiazine used in the treatment of psychoses. …
Amisulpride
Amisulpride is a benzamide derivative and a dopamine receptor antagonist that selectively works on dopamine D2 and D3 receptors. As an antipsychotic agent, amisulpride alleviates both positive and negative symptoms of schizophrenia, and it exhibits antidepressant properties in patients with psychiatric disorders, dysthymia, and major depression. Amisulpride predominantly works in...
Approved
Investigational
Matched Synonyms: … 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-O-anisamide ... 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide …
Matched Iupac: … 4-amino-5-(ethanesulfonyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide …
Matched Description: … and vomiting in adults, either as monotherapy or in combination with another antiemetic agent of a different ... [A6752, L32764] Oral tablets of amisulpride is used in European countries as a treatment for acute and ... Amisulpride is a benzamide derivative and a dopamine receptor antagonist that selectively works on dopamine …
Matched Iupac: … 4-amino-5-(ethanesulfonyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide …
Matched Description: … and vomiting in adults, either as monotherapy or in combination with another antiemetic agent of a different ... [A6752, L32764] Oral tablets of amisulpride is used in European countries as a treatment for acute and ... Amisulpride is a benzamide derivative and a dopamine receptor antagonist that selectively works on dopamine …
gamma-Aminobutyric acid
The most common inhibitory neurotransmitter in the central nervous system.
Approved
Investigational
Matched Synonyms: … 4-aminobutanoic acid ... 4-aminobutyric acid …
Matched Iupac: … 4-aminobutanoic acid …
Matched Description: … The most common inhibitory neurotransmitter in the central nervous system. …
Matched Iupac: … 4-aminobutanoic acid …
Matched Description: … The most common inhibitory neurotransmitter in the central nervous system. …
Alosetron
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer due to numerous ... In June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug ... bowel syndrome (IBS) in women. …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer due to numerous ... In June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug ... bowel syndrome (IBS) in women. …
Dexlansoprazole
Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of DB00448, which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes...
Approved
Investigational
Matched Synonyms: … (+)-2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)PYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZIMIDAZOLE ... 1H-BENZIMIDAZOLE, 2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)-2-PYRIDINYL)METHYL)SULFINYL)- ... 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … by blocking the (H+, K+)-ATPase enzyme. ... [A19566, A19568, A178084, A174244] Dexlansoprazole inhibits the final step in gastric acid production ... Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … by blocking the (H+, K+)-ATPase enzyme. ... [A19566, A19568, A178084, A174244] Dexlansoprazole inhibits the final step in gastric acid production ... Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated …
Phenyl aminosalicylate
Approved
Matched Synonyms: … Phenyl 4-aminosalicylate …
Matched Iupac: … phenyl 4-amino-2-hydroxybenzoate …
Matched Iupac: … phenyl 4-amino-2-hydroxybenzoate …
Nizatidine
A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Approved
Matched Synonyms: … N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamine …
Matched Iupac: … dimethyl[(4-{[(2-{[1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]methyl}-1,3-thiazol-2-yl)methyl …
Matched Description: … A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. …
Matched Products: … AXID INYECTABLE 100 MG/4 ML …
Matched Iupac: … dimethyl[(4-{[(2-{[1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]methyl}-1,3-thiazol-2-yl)methyl …
Matched Description: … A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. …
Matched Products: … AXID INYECTABLE 100 MG/4 ML …
Levoleucovorin
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic …
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Description: … This results in a deficiency of coenzymes and a resultant buildup of toxic substances that are responsible ... However, in order to function in this role, it must first be reduced by the enzyme dihydrofolate reductase ... As methotrexate functions as a DHFR inhibitor to prevent DNA synthesis in rapidly dividing cells, it …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Description: … This results in a deficiency of coenzymes and a resultant buildup of toxic substances that are responsible ... However, in order to function in this role, it must first be reduced by the enzyme dihydrofolate reductase ... As methotrexate functions as a DHFR inhibitor to prevent DNA synthesis in rapidly dividing cells, it …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 201 - 225 of 14997 in total