Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 1 - 25 of 14395 in total
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Synonyms: … Interferon beta (recombinant) ... HUMAN INTERFERON BETA ... Interferon beta (human) …
Matched Name: … Human interferon beta …
Matched Description: … Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis ... [A191784] Interferon beta is currently being studied as a possible treatment for COVID-19, which ... (MS), and was initially approved by the FDA in 1992. …
Matched Categories: … Interferon Type I ... Experimental Unapproved Treatments for COVID-19 ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational
Matched Synonyms: … Interferon alfa-n1 ... Interferon alpha-n1 (INS) …
Matched Name: … Interferon alfa-n1 …
Matched Description: … This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced ... Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least ... from individual alpha interferon genes. …
Matched Categories: … Interferon Type I ... interferon alfa-n1 ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Matched Synonyms: … Interferon alfa-n3 …
Matched Name: … Interferon alfa-n3 …
Matched Description: … Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms ... including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Interferon alpha ... Interferon-alpha ... Interferon Type I …
Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Synonyms: … Coagulation factor VIIa (recombinant) ... Coagulation factor VIIa (recombinant)-jncw …
Matched Name: … Coagulation factor VIIa Recombinant Human
Matched Description: … Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the ... Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … powder and solvent for solution for injection 2mg ... powder and solvent for solution for injection 1mg ... NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin. This transformation mimics the final coagulation cascade step which involves the clotting mass...
Approved
Matched Synonyms: … Thrombin human ... Thrombin (human) ... Thrombin Human Plasma-derived …
Matched Name: … Human thrombin …
Matched Description: … In particular, while human thrombin products are made from pooled human source plasma, recombinant thrombin ... is a human coagulation protein produced via recombinant DNA technology from a genetically modified Chinese ... achieves hemostasis and sealing of open tissues. …
Matched Mixtures name: … EVICEL Fibrin Sealant (Human) ... EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml …
Matched Products: … Thrombin Human
Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Synonyms: … Factor I human ... Fibrinogen human ... Fibrinogen (human) …
Matched Name: … Fibrinogen human
Matched Description: … Fibrinogen concentrate (human) is a hematological agent. ... It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and
Matched Mixtures name: … EVICEL Fibrin Sealant (Human) ... EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/ml …
Matched Categories: … fibrinogen, human ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Fibryga 1g Powder and Solvent for Solution for Injection or Infusion ... FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL …
Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect. It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. It is used as an alternative for people developing antibodies against salmon calcitonin.
Approved
Investigational
Matched Synonyms: … Calcitonin human ... Calcitonin (human) ... Calcitonin, human
Matched Name: … Human calcitonin …
Matched Categories: … Sex Hormones and Insulins ... calcitonin (human synthetic) …
Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Synonyms: … Human IGG ... Human gammaglobulin ... Human immunoglobulin G …
Matched Name: … Human immunoglobulin G …
Matched Description: … Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human ... IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population ... The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and
Matched Categories: … Human Immunoglobulin G ... Amino Acids, Peptides, and Proteins …
Matched Products: … LIV-GAMMA SN INJ ... LİV-GAMMA SN 5 G/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... LİV-GAMMA SN 2,5 G/50 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET …
Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation cascade [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key...
Approved
Investigational
Matched Synonyms: … Coagulation factor XIII, recombinant ... Factor XIII, human ... Human coagulation factor XIII …
Matched Name: … Factor XIII (human) …
Matched Description: … is a recombinant form of the A subunit of human coagulation factor XIII. ... recombinant DNA technology where the target protein is grown in yeast and then isolated [FDA Label]. ... Other drug products with similar structure and function to Factor XIII (human) include [DB09310], which …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to continuously secrete the hormone progesterone during the first...
Approved
Vet approved
Matched Synonyms: … Human chorionic gonadotropin ... Human menopausal gonadotropin ... Human-chorionic gonadotropin …
Matched Name: … Chorionic Gonadotropin (Human) …
Matched Description: … Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. ... HCG is composed of an alpha and a beta sub-unit. ... Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Human Chorionic Gonadotrophin ... Powder and Solvent for Solution for Injection ... Choriomon 5000 IU powder and solvent for solution for injection …
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Synonyms: … Antithrombin III (human) ... Antithrombin III human ... Antithrombin III,human
Matched Name: … Antithrombin III human
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles. First approved in October 2017 by the Food and Drug Administration, Shingrix is the preferred vaccine for preventing varicella zoster infection in people aged 50 years and older, replacing...
Approved
Investigational
Matched Synonyms: … gE recombinant Varicella zoster virus (VZV) glycoprotein E ... Recombinant Varicella zoster virus (VZV) glycoprotein E ... gE: Recombinant Varicella Zoster Virus (VZV) glycoprotein E …
Matched Name: … Varicella zoster vaccine (recombinant) …
Matched Description: … non-live recombinant vaccine indicated for prevention of shingles. ... Recombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted ... efficacy in preventing postherpetic neuralgia in patients 70 years and older and 91% efficacy in patients …
Matched Products: … SHINGRIX POWDER AND SUSPENSION FOR SUSPENSION FOR INJECTION 50MCG/0.5ML …
The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Synonyms: … Human von willebrand factor ... Von willebrand factor (human) ... von Willebrand factor, human
Matched Name: … Von Willebrand factor human
Matched Description: … [L1878] A recombinant form of vWF, [vonicog alfa], is also available to enhance production and avoid ... The human vWF is used to manage and control bleeding episodes in patients with von Willebrand disease ... The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 58 L1 protein ... L1 protein, Human papillomavirus type 58 Vaccine …
Matched Name: … Human papillomavirus type 58 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) type 58. ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 58 which are produced by separate fermentations in recombinant
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 11 L1 protein ... L1 protein, Human papillomavirus type 11 Vaccine …
Matched Name: … Human papillomavirus type 11 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... 18, which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and self-assembled …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the...
Approved
Matched Synonyms: … Human herpesvirus 3 immune globulin ... Varicella zoster immune globulin human ... Varicella zoster immune globulin (human) …
Matched Name: … Human varicella-zoster immune globulin …
Matched Description: … It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and ... VariZIG to reduce the disease severity in high-risk patients who lack evidence of immunity to varicella and ... human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). …
Matched Categories: … Human Varicella Zoster Immune Globulins ... Fluids and Secretions ... Amino Acids, Peptides, and Proteins …
Matched Products: … Varicella-zoster Immune Globulin (human) …
Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody [FDA Label, A33814]. The IgG fraction is purified by the anion-exchange column chromatography...
Approved
Matched Synonyms: … Human vaccinia immune globulin ... Vaccinia Immune Globulin (Human) Intravenous ... Vaccinia immune globulin intravenous (human) …
Matched Name: … Human vaccinia virus immune globulin …
Matched Description: … Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG ... Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human ... The IgG fraction is purified by the anion-exchange column chromatography method and the solution is solvent …
Matched Categories: … Human Immunoglobulin G ... Amino Acids, Peptides, and Proteins …
Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as...
Approved
Withdrawn
Matched Synonyms: … Lipoprotein OspA antigen recombinant
Matched Name: … Lyme disease vaccine (recombinant OspA) …
Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Synonyms: … Hepatitis B surface antigen (recombinant) …
Matched Name: … Hepatitis B Vaccine (Recombinant) …
Matched Description: … the chronic complications such as chronic active hepatitis and cirrhosis. ... epidemiology vary widely among geographical areas and population subgroups. ... Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B …
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain A (H1N1) …
Matched Name: … Influenza A virus subtype H1N1 haemagglutinin, recombinant
Matched Categories: … Recombinant influenza vaccines …
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain B (Victoria) …
Matched Name: … Influenza B virus Victoria lineage haemagglutinin, recombinant
Matched Categories: … Recombinant influenza vaccines …
Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced in Escherichia coli (E. coli) by recombinant DNA technology. With a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids in length in comparison to the natural IL-11, which is 178 amino acid...
Approved
Investigational
Matched Synonyms: … Recombinant interleukin-11 ... Interleukin 11 ... Interleukin-11 …
Matched Description: … Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced ... in Escherichia coli (E. coli) by recombinant DNA technology. ... In mice and nonhuman primate studies of animals with moderate and severe myelosuppression, in addition …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved
Matched Synonyms: … Botulism immune globulin IV human ... Botulism immune globulin intravenous (human) ... Human-derived botulism antitoxin antibodies …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … [L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in ... from persons immunized with recombinant botulinum vaccine who have high titers of neutralizing antibodies ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma …
Matched Categories: … Human Immunoglobulin G …
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant human adamts13 ... Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs ... Metalloproteinase ADAMTS13 (human recombinant BAX930) …
Matched Description: … [A262071] Apadamtase alfa, sold under the brand name Adzynma (ADAMTS13, recombinant-krhn), was approved ... rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and
Matched Categories: … Recombinant Proteins ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
Displaying drugs 1 - 25 of 14395 in total