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Displaying drugs 2976 - 3000 of 15190 in total
The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Approved
Investigational
Matched Synonyms: … Probenecid acid ... p-(Dipropylsulfamoyl)benzoic acid ... 4-((Dipropylamino)sulfonyl)benzoic acid
Matched Iupac: … 4-(dipropylsulfamoyl)benzoic acid
Matched Description: … It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. ... Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal …
Matched Mixtures name: … Probenecid and Colchicine ... Probenecid and Colchicine ... Probenecid and Colchicine …
Matched Categories: … Preparations Increasing Uric Acid Excretion ... Preparations With No Effect on Uric Acid Metabolism ... colchicine and probenecid ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Synonyms: … 3-Benzoylhydratropic acid ... m-Benzoylhydratropic acid ... 2-(3-Benzoylphenyl)propionic acid
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid
Matched Description: … and antipyretic properties. ... Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic …
Matched Categories: … Arylpropionic acid NSAIDS ... Ketoprofen and isomer ... Amino Acids, Peptides, and Proteins ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain …
Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Synonyms: … -3-C-formyl-beta-L-lyxopentanofuranoside ... 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl) …
Matched Description: … Medicine for their discovery of streptomycin and its antibacterial activity. ... [A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in ... Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and
Matched Categories: … Alimentary Tract and Metabolism ... streptomycin and isoniazid …
Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Synonyms: … Alpha-L-iduronate sulfate sulfatase …
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and ... Idursulfase is a 525-amino acid glycoprotein with a molecular weight of approximately 76 kilodaltons. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants With Advanced Parkinson's Disease).
Approved
Investigational
Matched Synonyms: … 3-hydroxy-O-phosphono-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-[3-hydroxy-4-(phosphonooxy)phenyl]propanoic acid
Matched Description: … Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and
Matched Categories: … Dopa and Dopa Derivatives ... foslevodopa and decarboxylase inhibitor …
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Synonyms: … L-OHP …
Matched Description: … refractory to an initial fluorouracil and leucovorin combination. ... Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. ... [A260396] The DACH moiety also prevents cross-resistance with cisplatin and carboplatin. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Synonyms: … L(−)-nicotine …
Matched Description: … the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening …
Matched Products: … Up and Up Nicotine ... Up and Up nicotine ... Up and Up Mini Nicotine …
Approved
Matched Mixtures name: … Menthol and Zinc Oxide ... Menthol and Zinc Oxide ... Menthol and Zinc Oxide
Matched Products: … Zims Arnica Max ... Arnica Pain Relief ... SmartMouth Mouth Sore Zinc Activated Formula …
Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
Approved
Vet approved
Matched Synonyms: … Colistin methanesulfonic acid ... Colistinmethanesulfonic acid
Matched Categories: … Amino Acids, Peptides, and Proteins …
Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.
Approved
Matched Synonyms: … Penicillanic acid sulfone ... Penicillanic acid 1,1-dioxide ... (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide …
Matched Iupac: … (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Description: … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. ... [L50131] When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect …
Matched Mixtures name: … Ampicillin and Sulbactam ... Ampicillin and Sulbactam ... Ampicillin and Sulbactam …
Matched Categories: … Beta-Lactam Antibacterials …
Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli. People take sulfur...
Approved
Matched Description: … Sulfur is also found in garlic, onions and broccoli. ... After calcium and phosphorus, it is the third most abundant mineral in the human body. ... allergies, swelling in the back of the throat (pharyngitis), high cholesterol, clogged arteries, menopause, and
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... Dermaharmony Sulfur and Salicylic Acid
Matched Products: … Margarite Zinc Cream ... Spai-sons Acid Anti-dandruff ... Renu Laboratories Acne Sulphur L
A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. It is used in commercial drug preparations to solubilize drugs for injection
Approved
Matched Synonyms: … l-α-dimyristoylphosphatidylcholine …
Matched Description: … A synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. …
Matched Categories: … Indicators and Reagents …
Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Synonyms: … Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside …
Matched Description: … bacilli and gram-negative bacilli. ... used off-label in the treatment of toxoplasmosis, malaria, and babesiosis. ... [A190621] Interestingly, clindamycin appears to carry some activity against protozoans, and has been …
Matched Mixtures name: … Clindamycin and Benzoyl Peroxide ... Clindamycin Phosphate and Tretinion ... Clindamycin and Benzoyl Peroxide …
Matched Categories: … Genito Urinary System and Sex Hormones ... Macrolides, Lincosamides and Streptogramins ... Gynecological Antiinfectives and Antiseptics …
Cefamandole is also known as cephamandole. It is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, cefamandole nafate. It is no longer marketed in the United States.
Approved
Experimental
Matched Synonyms: … L-Cefamandole ... [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... Mandelamido-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-carboxylic acid
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched Synonyms: … m,N-Dimethylthiocarbanilic acid O-2-naphthyl ester ... Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester …
Matched Description: … and ringworm. ... It is sold under several brand names, most notably Tinactin and Odor Eaters. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … Up and Up Antifungal ... Fungi Nail Toe and Foot ... Up and Up Soothing Antifungal …
A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
Approved
Matched Synonyms: … meso-dimercaptosuccinic acid ... meso-2,3-dimercaptosuccinic acid
Matched Iupac: … (2R,3S)-2,3-disulfanylbutanedioic acid
Matched Description: … A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates …
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical...
Approved
Matched Synonyms: … 5-aminosalicylic acid ... m-Aminosalicylic acid
Matched Iupac: … 5-amino-2-hydroxybenzoic acid
Matched Description: … drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022]. ... An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory ... Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine …
Matched Products: … Ntp-5-aminosalicylic Acid
Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Some adverse effects of carbamide peroxide as a dental bleaching agent include...
Approved
Matched Description: … /or gingival irritation led by unstable and reactive H+ free radicals and low pH from prolonged use. ... As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products ... Some adverse effects of carbamide peroxide as a dental bleaching agent include dentin sensitivity and
Matched Products: … Gly-Oxide ... Ear Wax Removal Drops Up and Up ... Foster and Thrive Earwax Removal Drops …
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Synonyms: … N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine ... N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine …
Matched Iupac: … (2S)-3-methyl-2-(N-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}pentanamido)butanoic acid
Matched Description: … aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. ... and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of ... preventing ventricular hypertrophy and remodelling. …
Matched Mixtures name: … AMLODIPINE and VALSARTAN ... Amlodipine and Valsartan ... Amlodipine and Valsartan …
Matched Categories: … valsartan and nebivolol ... valsartan and diuretics ... valsartan and aliskiren ... valsartan and amlodipine ... valsartan and sacubitril …
A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.
Approved
Matched Synonyms: … -(((1-methyl-1H-tetrazol-5- yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2- carboxylic acid
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … of both aerobic and anaerobic gram-positive and gram-negative microorganisms. ... The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range …
Matched Products: … Cefotetan and Dextrose …
Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.[A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries that require high levels of visual accuracy. Brilliant blue G, like its name, imparts...
Approved
Matched Synonyms: … Acid Blue 90 ... Acid Blue 90 …
Matched Description: … [A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries …
Matched Categories: … Indicators and Reagents …
Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Matched Synonyms: … Nicotinic acid, methyl ester ... 3-pyridinecarboxylic acid methyl ester …
Matched Description: … muscle and joint pains [F64]. ... an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and ... methyl nicotinate is used to treat respiratory diseases, vascular disorders, rheumatoid arthritis, and
An important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. It is used in the treatment of psoriasis; acne vulgaris;...
Approved
Investigational
Matched Synonyms: … 9(Z)-Retinoic acid ... 9-cis-retinoic acid ... (7E,9Z,11E,13E)-retinoic acid
Matched Iupac: … (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
Matched Description: … Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth ... An important regulator of gene expression during growth and development, and in neoplasms. ... ; and embryonic development. …
Matched Categories: … Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Acid maltase ... Acid-alpha glucosidase ... Human acid precursor alpha-glucosidase, recombinant …
Matched Description: … Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the ... It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients. ... glycoprotein with a calculated mass of 98,008 daltons for the 883 residue mature polypeptide chain, and
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Approved
Matched Synonyms: … 1-Methyl-5-p-toluoylpyrrole-2-acetic acid ... 5-(p-Toluoyl)-1-methylpyrrole-2-acetic acid ... 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid
Matched Iupac: … 2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Heteroaryl acetic acid NSAIDS ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Displaying drugs 2976 - 3000 of 15190 in total