Displaying drugs 26 - 50 of 1931 in total
Rabies virus inactivated antigen, B
Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure prophylaxis against rabies.
Approved
Matched Synonyms: … Rabies virus vaccine wistar strain PM-1503-3M (human) …
Matched Description: … Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure …
Matched Categories: … Immune Sera and Immunoglobulins …
Matched Products: … RABIES VACCINE FOR HUMAN USE (VERO CELL), FREEZE-DRIED FINAL BULK …
Matched Description: … Inactivated rabies virus antigen B is a component of rabies vaccines used for pre- and post-exposure …
Matched Categories: … Immune Sera and Immunoglobulins …
Matched Products: … RABIES VACCINE FOR HUMAN USE (VERO CELL), FREEZE-DRIED FINAL BULK …
Thrombomodulin Alfa
Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism.
Approved
Investigational
Matched Synonyms: … Thrombomodulin (human 498-amino acid fragment) …
Matched Description: … It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Receptors, Thrombin ... Amino Acids, Peptides, and Proteins …
Matched Description: … It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Receptors, Thrombin ... Amino Acids, Peptides, and Proteins …
Lecanemab
Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952] with high selectivity to Aβ...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human beta-amyloid protofibril) (human-mus musculus monoclonal BAN2401 heavy ... chain), disulfide with human-mus musculus monoclonal BAN2401 light chain, dimer …
Matched Description: … [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 ... recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 ... recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Adenovirus type 7 vaccine live
Approved
Matched Synonyms: … Human adenovirus B serotype 7 strain 55142 antigen …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 7 Vaccine …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 7 Vaccine …
Talquetamab
Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … ) (HUMAN MONOCLONAL JNJ-63483043 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL JNJ-63483043 .LAMBDA ... IMMUNOGLOBULIN G4 (233-PROLINE,239-ALANINE,240-ALANINE,410-LEUCINE,414-LYSINE), ANTI-(HUMAN CD3 ANTIGEN ... -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND …
Matched Description: … [A260890] The Committee for Medicinal Products for Human Use (CHMP) of the EMA recommended conditional ... arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … [A260890] The Committee for Medicinal Products for Human Use (CHMP) of the EMA recommended conditional ... arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Menotropins
Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Synonyms: … Human menopausal gonadotrophin …
Matched Description: … Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the ... It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits …
Matched Categories: … human menopausal gonadotrophin ... Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Menopur Powder for Injection and Solvent 75 IU ... Menopur Powder and Solvent For Solution for Injection 75iu ... MENOPUR multidose 600IU Powder and Solvent for Solution for Injection …
Matched Description: … Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the ... It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits …
Matched Categories: … human menopausal gonadotrophin ... Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Menopur Powder for Injection and Solvent 75 IU ... Menopur Powder and Solvent For Solution for Injection 75iu ... MENOPUR multidose 600IU Powder and Solvent for Solution for Injection …
Aldesleukin
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … Recombinant human interleukin-2 ... Recombinant interleukin-2 human ... 125-L-serine-2-133-interleukin 2 (human reduced) …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... clone encodes a modified human interleukin-2. ... recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... clone encodes a modified human interleukin-2. ... recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Recombinant Human Alpha Mannosidase …
Matched Description: … deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy …
Matched Categories: … Recombinant Human Lysosomal alpha-Mannosidase ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy …
Matched Categories: … Recombinant Human Lysosomal alpha-Mannosidase ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Palifermin
Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli.
Palifermin was granted FDA approval on 15 December 2004.
Approved
Matched Synonyms: … 24-163 fibroblast growth factor 7 (human) …
Matched Description: … It is 140 residues long, and is produced using E. coli. ... Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … It is 140 residues long, and is produced using E. coli. ... Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Angiotensin II
Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy.
As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Synonyms: … Human angiotensin II ... Angiotensin II (human) …
Matched Description: … The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin ... and death within hours, no matter young or o ld. ... , Renin Angiotensin System, and Idiopathic Membranous Nephropathy. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin ... and death within hours, no matter young or o ld. ... , Renin Angiotensin System, and Idiopathic Membranous Nephropathy. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Teriparatide
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … Teriparatide recombinant human …
Matched Description: … [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. ... Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Parathyroid Hormones and Analogues ... Calcium-Regulating Hormones and Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. ... Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Parathyroid Hormones and Analogues ... Calcium-Regulating Hormones and Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Vonicog alfa
Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. It was FDA approved in December 2015. The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg. By the EMA, vonicog alfa is still under clinical analysis.
Approved
Investigational
Matched Synonyms: … Von willebrand factor, recombinant, human …
Matched Description: … [A32230] The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg …
Matched Description: … [A32230] The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg …
Laronidase
Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical...
Approved
Matched Synonyms: … Human Recombinant alpha-L-iduronidase …
Matched Description: … Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Vayarin
Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Matched Description: … Lipirinen_, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and ... Cost of the drug and patient aversion to the taste of Vayarin were significant reasons for therapy failure ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional …
Catridecacog
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) ... Human Factor XIII (A2) homodimer (allele F13A*1B), recombinant DNA origin …
Matched Description: … then isolated, the human form is isolated from pooled human plasma. ... When activated by thrombin at the site of injury, the FXIII A2B2 pro-enzyme is cleaved resulting in activation ... ) include [DB12909], which is a purified endogenous (human) form of coagulation factor XIII. …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … then isolated, the human form is isolated from pooled human plasma. ... When activated by thrombin at the site of injury, the FXIII A2B2 pro-enzyme is cleaved resulting in activation ... ) include [DB12909], which is a purified endogenous (human) form of coagulation factor XIII. …
Matched Categories: … Blood and Blood Forming Organs …
Dornase alfa
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Deoxyribonuclease (human clone 18-1 protein moiety) …
Matched Description: … Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. …
Matched Categories: … Recombinant Human Deoxyribonuclease 1 ... Enzymes and Coenzymes ... Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …
Matched Description: … Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. …
Matched Categories: … Recombinant Human Deoxyribonuclease 1 ... Enzymes and Coenzymes ... Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …
Coagulation Factor IX (Recombinant)
Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX recombinant human …
Matched Description: … It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically ... It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, ... and has structural and functional characteristics similar to those of endogenous factor IX. …
Matched Products: … BeneFIX Powder and Solvent for Solution for Injection 250iu/vial ... BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 1000iu/vial …
Matched Description: … It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically ... It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, ... and has structural and functional characteristics similar to those of endogenous factor IX. …
Matched Products: … BeneFIX Powder and Solvent for Solution for Injection 250iu/vial ... BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 1000iu/vial …
Atidarsagene autotemcel
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … ) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene ... Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … progenitor cells transduced _ex vivo_ using a lentiviral vector encoding the human arylsulfatase A ( ... Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … progenitor cells transduced _ex vivo_ using a lentiviral vector encoding the human arylsulfatase A ( ... Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Interferon alfa-2a
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Synonyms: … Recombinant human interferon alfa-2a ... Recombinant human interferon-alfa-2a …
Matched Description: … Interferon a (human leukocyte protein moiety reduced). ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Interferon a (human leukocyte protein moiety reduced). ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Follitropin
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … Recombinant human follicle stimulating hormone beta ... Recombinant human follicle-stimulating hormone (r-HFSH) …
Matched Description: … The alpha- and beta- subunits have 92 and 111 amino acids. ... 7 and Asn 24. ... Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which …
Matched Mixtures name: … MENOGON 75 IU Powder and Solvent for solution for Injection ... Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … GONAL-F® 450 IU/0.75 ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... GONAL-F® 75 IU (5.5MCG) POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Matched Description: … The alpha- and beta- subunits have 92 and 111 amino acids. ... 7 and Asn 24. ... Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which …
Matched Mixtures name: … MENOGON 75 IU Powder and Solvent for solution for Injection ... Pergoveris 150IU/75IU powder and solvent for solution for injection ... Pergoveris Powder and Solvent for Solution for Injection 150iu/75iu …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … GONAL-F® 450 IU/0.75 ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... GONAL-F® 75 IU (5.5MCG) POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Loncastuximab tesirine
Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through …
Matched Description: … and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … and improve survival. ... Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Mecasermin rinfabate
Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Synonyms: … Recombinant human insulin-like growth factor-I/insulin-like growth factor binding protein-3 …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …
Insulin lispro
Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Synonyms: … Insulin,lispro,human/rDNA …
Matched Description: … is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... then to a monomer that is absorbed more rapidly after subcutaneous injection compared to endogenous human ... Formerly called LYSPRO from the chemical nomenclature [LYS(B28), PRO(B29)], insulin lispro differs from human …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen …
Matched Description: … is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... then to a monomer that is absorbed more rapidly after subcutaneous injection compared to endogenous human ... Formerly called LYSPRO from the chemical nomenclature [LYS(B28), PRO(B29)], insulin lispro differs from human …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Insulin Lispro Protamine and Insulin Lispro Injectable Suspension Mix75/25 KwikPen …
Alteplase
Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Technetium Tc-99m red blood cells
Technetium Tc-99m red blood cells is a radiopharmaceutical diagnostic agent that is intravenously administered to be used in blood pool imaging, including cardiac first pass and gated equilibrium imaging and for detection of sites of gastrointestinal bleeding. It is clinically useful in early detection and localization of bleeding sites, and...
Approved
Matched Synonyms: … Technetium Tc-99m red blood cell human …
Matched Description: … It is clinically useful in early detection and localization of bleeding sites, and preoperative diagnosis ... gated equilibrium imaging and for detection of sites of gastrointestinal bleeding. ... agent that is intravenously administered to be used in blood pool imaging, including cardiac first pass and …
Matched Description: … It is clinically useful in early detection and localization of bleeding sites, and preoperative diagnosis ... gated equilibrium imaging and for detection of sites of gastrointestinal bleeding. ... agent that is intravenously administered to be used in blood pool imaging, including cardiac first pass and …
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