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Displaying drugs 51 - 75 of 5219 in total

TN-401

TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Investigational
Matched Synonyms: … A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and …

Human Embryonic Stem Cell-derived M Cell

CAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. These IMRCs are differentiated from human embryonic stem cells that are expanded and then harvested. These cells are currently being investigated against lung injury and fibrosis -- conditions which are...
Investigational
Matched Synonyms: … immunity- and matrix-regulatory cells ... Immunity-and-matrix-regulatory cells …
Matched Description: … outcomes of lung disorders including COVID-19. ... and fibrosis. ... immunomodulatory and anti-fibrotic functions, and being stronger in potential treatment of lung injury …

CAM-GM201

Investigational
Matched Synonyms: … rAAV2/1 Hex alpha and beta ... Recombinant adeno-associated viral vector serotype 2/1 encoding human beta-hexosaminidase alpha and beta …

Ranitidine

Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.[A176759,L10818] Ranitidine is often referred to as...
Approved
Withdrawn
Matched Iupac: … [1-({2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}amino)-2-nitroethenyl](methyl)amine …
Matched Description: … gastric acid associated conditions and is therefore widely used in GERD and other gastric-acid related ... This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of ... the same drug class as [cimetidine] and [famotidine]. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Heterocyclic Compounds, 1-Ring ... Acid Reducers ... Gastric Acid Lowering Agents …
Matched Products: … Berkley and Jensen Acid Reducer ... Up and Up Ranitidine 150 ... Up and Up Acid Reducer Non Prescription Strength …

Esomeprazole

Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched International brands: … Awa-Block …
Matched Iupac: … 5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of ... iron and B12, and an increased risk of developing hypomagnesemia and hypocalcemia which may contribute ... to osteoporosis and bone fractures later in life. …
Matched Salts cas: … 161973-10-0 ... 217087-10-0 …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Categories: … Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... naproxen and esomeprazole ... Heterocyclic Compounds, 1-Ring ... Antiinflammatory and Antirheumatic Products …
Matched Products: … Foster and Thrive Acid Reducer ... Up and Up Esomeprazole Magnesium ... Berkley and Jensen Heartburn Treatment …

Benzethonium

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. ... Food and Drug Administration (FDA). ... Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum …
Matched Salts cas: … 121-54-0 …
Matched Mixtures name: … Salicylic Acid ... Gold Bond Pain and Itch ... Benzocaine and Benzethonium …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Foaming Instant Hand Sanitizer with Aloe and Vitamin E ... LYSOL Healthy Touch Aloe Vera And Vitamin E with Moisturizers ... Piranha Brand Alcohol Free Foaming Instant Hand Sanitizer with Aloe and Vitamin E …

Hydrogen peroxide

Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it may undergo potentially explosive thermal decomposition....
Approved
Vet approved
Matched Description: … with a stabilizer in a weakly acidic solution. ... is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing agent ... and gas form for preservative, disinfection and sterilization applications as an oxidative biocide [A32369 …
Matched Mixtures name: … Prevention Wound and Burn ... QCare Oral Cleansing and Suctioning System, Q4 ... Oral Cleansing and Suctioning System, q2 …
Matched Categories: … Alimentary Tract and Metabolism ... Antiseptics and Disinfectants ... Antiinfectives and Antiseptics for Local Oral Treatment ... Compounds used in a research, industrial, or household setting …
Matched Products: … Salon Safety Furniture and Surface 1 Minute Sanitizer ... Up and Up 3 Hydrogen Peroxide Wipes ... Multi Purpose Sanitizer and Cleaner Wipes …

TN-201

TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.
Investigational
Matched Synonyms: … Native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … promoter and the wild-type human MYBPC3 gene. ... TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific …

Ergocalciferol

Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Synonyms: … Vitamin D2 ... Vitamin D-2 ... Vitamina D2 …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden- ... 4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol …
Matched Description: … [T580] Ergocalciferol is considered the first vitamin D analog and is differentiated from [cholecalciferol ... ] by the presence of a double bond between C22 and C23 and the presence of a methyl group at C24. ... Ergocalciferol is an inactivated vitamin D analog. …
Matched Mixtures name: … Vitamin D2 and K1 ... SAFWA HEALTH CALCIUM AND VITAMIN D ... Calcium With Vitamins C and D Tab …
Matched Categories: … Vitamin D and Analogues ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents ... Vitamins …
Matched Products: … Vitamin D ... VITAMINA D2 SALF ... Ergocalciferol (Vitamin D2) …

Vayarin

Vayarin is a prescription medical food for the clinical dietary management of certain lipid imbalances blamed to be associated with attention deficit hyperactivity disorder (ADHD) in children. Vayarin contains Lipirinen, a proprietary composition containing phosphatidylserine-omega 3, EPA (eicosapentaenoic acid), and docosahexaenoic acid (DHA) [L1500, L1510]. Vayarin is currently available only...
Approved
Investigational
Matched Synonyms: … Phosphatidylserine, DHA, and EPA …
Matched Description: … acid), and docosahexaenoic acid (DHA) [L1500, L1510]. ... Vayarin is a specially formulated and designed to address the distinct, previously determined lipid nutritional ... A slow response time of 12 weeks is an impediment to successful management of ADHD as only 41.6% of subjects …

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Synonyms: … 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine ... 2-cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine ... N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine …
Matched Iupac: … (Z)-N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine …
Matched Description: … It inhibits gastric acid secretion, as well as pepsin and gastrins output. ... Cimetidine has a range of pharmacological actions. ... A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. …
Matched Mixtures name: … Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% ... Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% …
Matched Categories: … Alimentary Tract and Metabolism ... Metabolic Side Effects of Drugs and Substances ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... Acid Reducers ... MATE 1 Inhibitors …
Matched Products: … Up and Up Acid Reducer ... SHINTAMET INJECTION 150 mg/ml ... ไซแอมมิดีน ชนิดฉีด (100 มก./มล.) …

EDIT-301

EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2).
Investigational
Matched Synonyms: … ) at the HBG1 and HBG2 promoters ... Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 ... autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP …
Matched Description: … cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2). ... EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …

Polyethylene glycol

Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … [A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water ... when molecular weights are <1000 and the molecule turns to waxy solids with increasing molecular weights ... PEGs differ in their physical and chemical properties depending on their molecular weight: PEGs are liquids …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... PCP 100 Kit ... PEG-3350 and Electrolytes …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting …
Matched Products: … Up and Up Powderlax ... Berkley and Jensen Clearlax ... Foster and Thrive Clearlax …

Padimate O

Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic ... Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in ... concentrations up to 8%, as regulated by the FDA [L2153]. …
Matched Mixtures name: … Sun and Ski Stick SPF 15 ... Aruba Aloe Lip Sunscreen and Moisturizer ... Phineas and Ferb Sun Smacker SPF 24 Berry Busted …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Products: … Hand and Body Lotion SPF 15 ... Green Tea and Ginkgo Moisturizer SPF 10 ... Mentholatum Natural Ice Lipbalm With Moisturizing Vitamin E & Aloe Vera …

Stannous fluoride

Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective...
Approved
Matched Description: … It manages and prevents dental caries and gingivitis by promoting enamel mineralization [A19580], reducing ... in toothpastes, stannous fluoride has been shown to be more effective at stopping and reversing dental ... of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting …
Matched Products: … Sensodyne Sensitivity and Gum Clean and Fresh ... Rite Aid Sensitivity and Gum ... Rite Aid Gum and Enamel Repair …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Iupac: … 3-yl)methyl]-1,4,7,10,13,16-hexaoxo-3-phenyl-icosahydropyrrolo[1,2-a]1,4,7,10,13,16-hexaazacyclooctadecan ... (3S,6R,9S,12S,15S,19R,20aS)-9-(4-aminobutyl)-15-benzyl-12-{[4-(benzyloxy)phenyl]methyl}-6-[(1H-indol- ... -19-yl N-(2-aminoethyl)carbamate …
Matched Description: … It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease ... Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Somatostatin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR (10 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... Signifor LAR 20mg powder and solvent for suspension for injection …

Tranexamic acid

Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Synonyms: … trans-4-aminomethylcyclohexane-1-carboxylic acid ... Tranexmic acid ... Tranexamic acid …
Matched Name: … Tranexamic acid …
Matched Iupac: … (1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylic acid …
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Products: … TRANSAMINE 100 MG/ML IV ENJ COZELTI, 10 ADET ... Cyklokapron 100 mg/ml ... TRANSAMIN S INJECTION 10% …

Butylene glycol

Approved
Experimental
Matched Synonyms: … 1,3-Butandiol ... 1,3-Butanediol ... (RS)-1,3-Butandiol …
Matched Iupac: … butane-1,3-diol …
Matched Products: … Dr.g Lock and More Nourishing Mask ... Dr.g Lock and More Sensi Calming Mask ... PLAY and JOY Cologne Maca Extra Hot Lubricant PJ-LBS201-35EU …

Hiltonol

Investigational
Matched Synonyms: … carboxymethyl ether and l-lysine homopolymer ... carboxymethyl ether and l-lysine homopolymer ... L-lysine, homopolymer, compd. with cellulose carboxymethyl ether and 5'-inosinic acid homopolymer complex …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Amino Acids ... Amino Acids, Basic …

Moroctocog alfa

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … amino acid, 170 kDa protein [FDA Label]. ... purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... as a result, leads to easy bruising and bleeding. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …

Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen

Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... is harvested and grafted onto the burn site - which has the disadvantage of creating a new wound at …

ALX-009

Investigational
Matched Synonyms: … Hypothiocyanite and lactoferrin ... ALX-009 …
Matched Name: … ALX-009 …

Carboxymethylcellulose

Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or thickener and emulsifier. It is also one of the most common viscous polymers used in...
Approved
Investigational
Matched Description: … It is added in food products as a viscosity modifier or thickener and emulsifier. ... The viscous and mucoadhesive properties as well as its anionic charge allow prolonged retention time ... monomers and their hydroxyl groups bound to carboxymethyl groups. …
Matched Mixtures name: … Equate Day and Night Restore Tears ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) …
Matched Categories: … Anorexigenic Agents & Respiratory and CNS Stimulants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Up and Up Lubricant ... Up and Up Lubricant Refreshing ... Up and Up Lubricant Refreshing Tears …

SP1049C

SP1049C is a novel anthracycline chemotherapeutic agent containing doxorubicin and two nonionic pluronic block copolymers. It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review. Preliminary data, in its first clinically tested indication,...
Investigational
Matched Synonyms: … doxorubicin with pluronics F-127 and L-61 ... Doxorubicin HCl with pluronic L-61 and pluronic F-127 …
Matched Description: … SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic ... Median survival is encouraging and correlates strongly with dose levels.[A260416] ... It has successfully completed Phase 1 trials. Phase 2 results are currently under final review. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Octasulfur

Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli. People take sulfur...
Approved
Matched Description: … Sulfur is also found in garlic, onions and broccoli. ... After calcium and phosphorus, it is the third most abundant mineral in the human body. ... allergies, swelling in the back of the throat (pharyngitis), high cholesterol, clogged arteries, menopause, and …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... Dermaharmony Sulfur and Salicylic Acid …
Matched Products: … Rodan and Fields Unblemish 1 Wash Acne Medicated Cleanser ... Acne All-Star 3-in-1 Acne Cleanser, Mask and Spot Treatment ... Malin and Goetz Acne Treatment …
Displaying drugs 51 - 75 of 5219 in total