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Displaying drugs 76 - 100 of 671 in total

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Synonyms: … Eptacog alfa (activated) …
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... NOVOSEVEN 1MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... powder and solvent for solution for injection 2mg …

Reteplase

Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. ... Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. …
Matched Categories: … Tissue Plasminogen Activator ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature …

Turoctocog alfa

Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and ... [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid 720, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …

Triclosan

An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Description: … sports equipment and shoes. ... An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy ... It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, …
Matched Mixtures name: … Benzocaine and Triclosan ... Benzocaine and Triclosan ... Ecosave Grapefruit and Lemongrass Soap Antibacterial Hand Soap …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … Antibacterial Foaming Olive and Aloe ... Mint and Aloe Antibacterial Foaming Hand Wash ... Citrus and Aloe Antibacterial Foaming Hand Wash …

Romilkimab

Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational
Matched Synonyms: … Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13) …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in …

Carbidopa

Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Description: … It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …

DCVAC/OvCa

DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …

CHF5633

CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Eupatorium capillifolium pollen

Eupatorium capillifolium pollen is the pollen of the Eupatorium capillifolium plant. Eupatorium capillifolium pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Dog Fennel, Eastern Eupatorium capillifolium ... Pollens - Weeds and Garden Plants, Dog Fennel Eupatorium capillifolium …

Lidocaine

Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched Description: … Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an ... , it can block or decrease muscle contractile, resulting in effects like vasodilation, hypotension, and ... Nevertheless, lidocaine's local anesthetic action sees its use in many medical situations or circumstances …
Matched Mixtures name: … Activate Joint and Muscle Relief ... De La Cruz Mercurochrome ... BAKERS BEST Pain Relief with Pure Hemp Seed Oil …
Matched Categories: … Analgesics and Anesthetics ... Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Terrasil Rash and Pain Relief ... Terrasil Itch, Rash and Pain Relief MAX ... Soulus Rp Rash and Pain …

Acetaminophen

Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Description: … of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines ... tablets, injection, suppository, and other forms. ... Acetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and …
Matched Mixtures name: … Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate and Acetaminophen …
Matched Categories: … Acetaminophen and Prodrugs ... tramadol and paracetamol ... codeine and paracetamol ... oxycodone and paracetamol ... hydrocodone and paracetamol …
Matched Products: … De La Cruz Dolofebril Infant ... De La Cruz Dolofebril Children ... Pain and Fever …

VOR33

VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …

Omalizumab

Omalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). IgE promotes the release of inflammatory mediators from mast cells and basophils during allergic and inflammatory reactions. By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its...
Approved
Investigational
Matched Description: … , and asthma. ... and inflammatory reactions. ... By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xolair 75mg Powder and Solvent for Solution for Injection ... XOLAIR 150MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Xolair 150mg Powder and Solvent for Solution for Injection …

Hydrocodone

Hydrocodone is a synthetic opioid derivative of codeine. It is commonly used in combination with acetaminophen to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by dextromethorphan in current cough and cold formulations. Hydrocodone's more potent metabolite, hydromorphone...
Approved
Illicit
Investigational
Matched Description: … a cough suppressant although this has largely been replaced by [dextromethorphan] in current cough and ... Hydrocodone's more potent metabolite, [hydromorphone] has also found wide use as an analgesic and is …
Matched Mixtures name: … Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate and Acetaminophen …
Matched Categories: … Cough and Cold Preparations ... hydrocodone and ibuprofen ... Opium Alkaloids and Derivatives ... hydrocodone and paracetamol …
Matched Products: … Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate And Acetaminophen …

Trolamine salicylate

Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Description: … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and ... It also displays low systemic absorption upon dermal or topical administration [A32190] and has low skin …
Matched Products: … Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream ... Blue-Emu Ultra with Hemp Seed …

Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe)

Experimental
Matched Name: … Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe) …

Chenopodium album pollen

Chenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album …

Ostrea edulis shell

Ostrea edulis shell is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Oyster Shell ... Mud Oyster Shell ... Common Oyster Shell …
Matched Name: … Ostrea edulis shell …
Matched Description: … Ostrea edulis shell is an animal extract used in some OTC (over-the-counter) products. …

Sunflower oil

Sunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Synonyms: … Sunflower Seed Oil ... Helianthus Annuus Seed Oil ... Helianthus Annuus (Sunflower) Seed Oil …
Matched Products: … OrgaPlus Super Care Balm for combination and oi ly skin type 20g ... OrgaPlus Super Care Balm for combination and oi ly skin type 14g …

Wormwood

Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Products: … Seborrheic Dermatitis and Psoriasis ... Seborrheic Dermatitis and Psoriasis Cream …

Chorionic Gonadotropin (Human)

Human chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta. Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance of the corpus luteum during the beginning of pregnancy. This allows the corpus luteum to continuously secrete the hormone progesterone during the first...
Approved
Vet approved
Matched Description: … HCG is composed of an alpha and a beta sub-unit. ... Endogenously produced HCG interacts with the LHCG receptor of the ovary and promotes the maintenance ... the hormone progesterone during the first trimester, which is required for maintenance of the uterus and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Powder and Solvent for Solution for Injection ... Choriomon 5000 IU powder and solvent for solution for injection ... PUBERGEN 7500IU (Chorionic Gonadotropin for Injection USP 7500IU/Vial and Sodium Chloride Injection USP …

Miconazole

Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027,...
Approved
Investigational
Vet approved
Matched Description: … [A203636] It is widely used to treat mucosal yeast infections, including both oral and vaginal infections ... although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and ... [A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January …
Matched Mixtures name: … Up and Up Miconazole 1 ... Up and Up Miconazole 1 ... Up and Up Miconazole 1 …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Imidazole and Triazole Derivatives ... Vaginal Creams, Foams, and Jellies ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Up and Up Miconazole 7 ... Soothe And Cool Treat ... Up and Up Jock Itch Relief …

Goflikicept

Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein ... Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and …
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …

Carbamide peroxide

Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Some adverse effects of carbamide peroxide as a dental bleaching agent include...
Approved
Matched Description: … /or gingival irritation led by unstable and reactive H+ free radicals and low pH from prolonged use. ... urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and ... As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products …
Matched Products: … Ear Wax Removal Drops Up and Up ... CareOne Earwax Removal Kit, Earwax and Bulb ... Foster and Thrive Earwax Removal Drops …
Displaying drugs 76 - 100 of 671 in total