Displaying drugs 76 - 100 of 192 in total
Rosuvastatin
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Synonyms: … (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5- ... -6-enoic acid ... dihydroxy-6-heptenoic acid …
Matched Iupac: … -6-enoic acid ... (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept …
Matched Description: … coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks. ... for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... with this statin through antagonism of OATP1B1 organic anion transporter protein 1B1-mediated hepatic …
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Alimentary Tract and Metabolism ... rosuvastatin and ramipril ... rosuvastatin and valsartan ... rosuvastatin and ezetimibe …
Matched Products: … ROSUVASTATIN 1 A 5MG ... ROSUVASTATIN 1 A 10MG ... ROSUVASTATIN 1 A 20MG …
Matched Iupac: … -6-enoic acid ... (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept …
Matched Description: … coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks. ... for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... with this statin through antagonism of OATP1B1 organic anion transporter protein 1B1-mediated hepatic …
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Alimentary Tract and Metabolism ... rosuvastatin and ramipril ... rosuvastatin and valsartan ... rosuvastatin and ezetimibe …
Matched Products: … ROSUVASTATIN 1 A 5MG ... ROSUVASTATIN 1 A 10MG ... ROSUVASTATIN 1 A 20MG …
Talimogene laherparepvec
Talimogene laherparepvec is an oncolytic treatment used in local treatment of unresectable cutaneous, subcutaneous, and nodal lesions in patients with recurrent melanoma. It is a genetically administered herpes simplex virus 1 (HSV-1) that expresses human cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) with antitumor and immune-stimulating activities. It specifically replicates within...
Approved
Experimental
Investigational
Matched Description: … It is a genetically administered herpes simplex virus 1 (HSV-1) that expresses human cytokine granulocyte-macrophage ... It specifically replicates within tumor cells and causes lysis. ... colony stimulating factor (GM-CSF) with antitumor and immune-stimulating activities. …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Efalizumab
Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. The FDA approved efalizumab in 2003. It was later withdrawn...
Approved
Investigational
Withdrawn
Matched Description: … Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. ... Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Histrelin
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Synonyms: … 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-Nτ-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide ... L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-Nim-benzyl-histidyl-L-leucyl-L-arginyl-L-proline …
Matched Iupac: … (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(1-benzyl-1H-imidazol-4-yl)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)- …
Matched Description: … treatment for children with central precocious puberty (CPP) due to their capacity to reduce LH levels and …
Matched Categories: … Hormones and Related Agents ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(1-benzyl-1H-imidazol-4-yl)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)- …
Matched Description: … treatment for children with central precocious puberty (CPP) due to their capacity to reduce LH levels and …
Matched Categories: … Hormones and Related Agents ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Bulevirtide
Hepatitis D is considered the most severe type of viral hepatitis and leads to the rapid development of cirrhosis, severe decompensation of liver function, and an increased risk of mortality.[A226340,L30235] Until recently, there have been extremely limited treatments available for Hepatitis D infection. Bulevirtide, also known as Hepcludex, is a...
Approved
Investigational
Matched Description: … Hepatitis D is considered the most severe type of viral hepatitis and leads to the rapid development ... of cirrhosis, severe decompensation of liver function, and an increased risk of mortality. ... first approved for use in the EU on May 28, 2020; bulevirtide has been granted PRIME scheme eligibility and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Antilymphocyte immunoglobulin (horse)
Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes. It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. The result is polyclonal IgG that...
Approved
Investigational
Matched Description: … in the type of antigen product used to produce immunoglobulin (thymocytes, peripheral T cells, etc.) ... It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune ... Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human …
Matched Categories: … Antibody-Surface Protein Interactions ... Fluids and Secretions ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antibody-Surface Protein Interactions ... Fluids and Secretions ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Mifamurtide
Mifamurtide is an immunomodulator with antitumor activity via activation of macrophages and monocytes. Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). MDP is a motif present in all gram-positive and...
Approved
Experimental
Matched Iupac: … sodium (2R)-1-({2-[(2S)-2-[(4R)-4-carbamoyl-4-[(2S)-2-[(2R)-2-{[(2R,3R,4R,5R)-2-acetamido-4,5,6-trihydroxy ... -1-oxohexan-3-yl]oxy}propanamido]propanamido]butanamido]propanamido]ethyl phosphono}oxy)-3-(hexadecanoyloxy …
Matched Description: … Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is ... receptors (NLRs) and toll-like receptors present in macrophages and monocytes. ... signalling molecules and activators such as nucleotide-binding and oligomerization domain (NOD)-like …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … MEPACT 4 MG INFÜZYONLUK DISPERSIYON KONSANTRESI IÇIN TOZ ,FLAKON, 1 ADET …
Matched Description: … Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is ... receptors (NLRs) and toll-like receptors present in macrophages and monocytes. ... signalling molecules and activators such as nucleotide-binding and oligomerization domain (NOD)-like …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … MEPACT 4 MG INFÜZYONLUK DISPERSIYON KONSANTRESI IÇIN TOZ ,FLAKON, 1 ADET …
Hydrocortisone acetate
Approved
Vet approved
Matched Iupac: … 9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1- …
Matched Mixtures name: … Lidotral 5 Percent and Hydrocortisone 1 Percent with Peptides and Arnica ... Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1% ... HYDRODERM-C CREAM 1% …
Matched Categories: … 11-Hydroxycorticosteroids ... Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid ... HC 1% CREAM ... Corticreme 1% …
Matched Mixtures name: … Lidotral 5 Percent and Hydrocortisone 1 Percent with Peptides and Arnica ... Iodoquinol 1% - Hydrocortisone Acetate 2% - Aloe Polysaccharides 1% ... HYDRODERM-C CREAM 1% …
Matched Categories: … 11-Hydroxycorticosteroids ... Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … American Safety and First Aid ... HC 1% CREAM ... Corticreme 1% …
Sacituzumab govitecan
Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents. Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent advance in cancer treatment. One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2...
Approved
Investigational
Matched Description: … A193671] One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen ... Commission and Health Canada respectively. ... [L13002, A193674]
Sacituzumab govitecan was granted FDA approval on April 22nd, 2020 and is marketed …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … TRODELVY 200 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADET …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … TRODELVY 200 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADET …
Apalutamide
Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Matched Iupac: … 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2 …
Matched Description: … Higher prostate-specific antigen (PSA) and shorter PSA doubling time (PSA DT) are associated with a higher ... Approximately 10 to 20 % of prostate cancer cases are castration-resistant, and up to 16% of these patients ... Unlike bicalutamide, apalutamide antagonized AR-mediated signaling in AR overexpressing human CRPC cell …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Description: … Higher prostate-specific antigen (PSA) and shorter PSA doubling time (PSA DT) are associated with a higher ... Approximately 10 to 20 % of prostate cancer cases are castration-resistant, and up to 16% of these patients ... Unlike bicalutamide, apalutamide antagonized AR-mediated signaling in AR overexpressing human CRPC cell …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Sutimlimab
Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Synonyms: … Humanized IgG4 monoclonal antibody against total complement component 1, subcomponent s …
Matched Description: … Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies ... In approximately 90% of cases, patients develop immunoglobulin M (IgM) autoantibodies towards the I antigen ... [A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies ... In approximately 90% of cases, patients develop immunoglobulin M (IgM) autoantibodies towards the I antigen ... [A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Antihemophilic factor human
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Synonyms: … F8 protein, human ... factor VIII, human ... Factor VIII (human) …
Matched Name: … Antihemophilic factor human …
Matched Description: … Unfortunately, purification of protein from human plasma carries an increased risk of transmission of ... Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) ... and purified from extraneous plasma-derived protein by affinity chromatography. …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Protein Precursors ... Human Antihemophilic Factors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000 IU …
Matched Name: … Antihemophilic factor human …
Matched Description: … Unfortunately, purification of protein from human plasma carries an increased risk of transmission of ... Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) ... and purified from extraneous plasma-derived protein by affinity chromatography. …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Protein Precursors ... Human Antihemophilic Factors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000 IU …
Anthrax immune globulin human
Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. It is derived from the plasma of humans immunized with BioThrax (adsorbed anthrax vaccine), which is then further purified. Available as the product Anthrasil (FDA), the result is a solution for slow IV infusion containing...
Approved
Matched Synonyms: … Anthrax immune globulin human ... Anthrax immune globulin (human) ... Anthrax immunoglobulin (human) …
Matched Name: … Anthrax immune globulin human …
Matched Description: … Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. ... result is a solution for slow IV infusion containing polyclonal antibodies that bind the protective antigen ... (PA) component of Bacillus anthracis lethal and edema toxins. …
Matched Categories: … Human Immunoglobulin ... Amino Acids, Peptides, and Proteins …
Matched Name: … Anthrax immune globulin human …
Matched Description: … Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. ... result is a solution for slow IV infusion containing polyclonal antibodies that bind the protective antigen ... (PA) component of Bacillus anthracis lethal and edema toxins. …
Matched Categories: … Human Immunoglobulin ... Amino Acids, Peptides, and Proteins …
Vibrio cholerae CVD 103-HgR strain live antigen
Vibrio cholerae CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization against Vibrio cholerae serogroup O1. Cholera is an acute bacterial disease of the small intestine caused by Vibrio cholerae, which is gram-negative bacteria. Two serogroups of V. cholerae, O1 and O139, are causative...
Approved
Investigational
Matched Name: … Vibrio cholerae CVD 103-HgR strain live antigen …
Matched Description: … _Vibrio cholerae_ CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization ... A244489] The FDA approved the cholera vaccine containing _Vibrio cholerae_ CVD 103-HgR strain live antigen ... [L39729] It is indicated for individuals aged two years and older.[L12801] …
Matched Products: … Cholera Vaccine Strain 35a-and 41 8000m/cc …
Matched Description: … _Vibrio cholerae_ CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization ... A244489] The FDA approved the cholera vaccine containing _Vibrio cholerae_ CVD 103-HgR strain live antigen ... [L39729] It is indicated for individuals aged two years and older.[L12801] …
Matched Products: … Cholera Vaccine Strain 35a-and 41 8000m/cc …
Nogapendekin alfa
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc ... Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform) …
Matched Description: … Nogapendekin alfa is a human IL-15N72D variant. ... 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Nogapendekin alfa is a human IL-15N72D variant. ... 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and ... proliferation of natural killer cells and CD8+ memory T cells, which also synergistically enhance BCG …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Hepatitis B immune globulin
Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. According to the Centers for Disease Control...
Approved
Investigational
Matched Synonyms: … Hepatitis B immune globulin human ... Hepatitis B immune globulin (human) ... Human hepatitis B immunoglobulin …
Matched Description: … Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. ... HBIG is prepared from the plasma of donors who have high antibody levels of the hepatitis B surface antigen ... The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. …
Matched Categories: … Human Immunoglobulin ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET ... HEPAGAM B 312 IU/1 ML IM/IV ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ ... HEPABULİN SN 2.000 IU/10 ML IV ENJEKSİYONLUK ÇÖZELTİ , 1 ADET …
Matched Description: … Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. ... HBIG is prepared from the plasma of donors who have high antibody levels of the hepatitis B surface antigen ... The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. …
Matched Categories: … Human Immunoglobulin ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET ... HEPAGAM B 312 IU/1 ML IM/IV ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ ... HEPABULİN SN 2.000 IU/10 ML IV ENJEKSİYONLUK ÇÖZELTİ , 1 ADET …
Brentuximab vedotin
Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Synonyms: … Moab, chimeric, SGN-30, to CD30 antigen …
Matched Description: … In this type of lymphoma, large, abnormal lymphocytes (a type of white blood cell) are found in the lymph ... [L1737] The ECHELON-1 study results demonstrated superior efficacy of the drug combined with a chemotherapy ... Most individuals with Hodgkin's lymphoma have the classical type. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …
Matched Description: … In this type of lymphoma, large, abnormal lymphocytes (a type of white blood cell) are found in the lymph ... [L1737] The ECHELON-1 study results demonstrated superior efficacy of the drug combined with a chemotherapy ... Most individuals with Hodgkin's lymphoma have the classical type. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …
Cemiplimab
Cemiplimab is a fully human monoclonal antibody that works against programmed death receptor-1 (PD-1), which is a negative regulator of T cell function. By blocking PD-1, cemiplimab works to enhance T cell-mediated antitumour responses. Cemiplimab was first approved by the FDA on September 28, 2018, as the first FDA-approved treatment...
Approved
Investigational
Matched Description: … Cemiplimab is a fully human monoclonal antibody that works against programmed death receptor-1 (PD-1) ... [A39201,A254177,L4615] It was later approved to be used in basal cell carcinoma and non-small non-small ... [L43872] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended …
Matched Categories: … PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Alefacept
Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. Produced by CHO cells, mW is 91.4 kD.
Approved
Investigational
Withdrawn
Matched Description: … human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of ... human IgG1. ... Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the …
Matched Categories: … CD2-directed LFA-3/Fc Fusion Protein ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … CD2-directed LFA-3/Fc Fusion Protein ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Capromab pendetide
Capromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate tissue. When linked to pendetide, capromab is used as a chelating agent for the radionuclide Indium In-111 during imaging to evaluate...
Approved
Matched Description: … Capromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen ... (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate tissue …
Matched Categories: … Indicators and Reagents ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Indicators and Reagents ... Amino Acids, Peptides, and Proteins …
Belatacept
Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Investigational
Matched Description: … antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin ... Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated ... and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Janssen COVID-19 Vaccine
The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. The vaccine was created in collaboration with Johnson and Johnson (J&J), Janssen Pharmaceutical, and the Beth Israel Deaconess Medical Center. A preclinical study in hamsters infected with...
Approved
Investigational
Matched Description: … , and efficacy of the ad26.COV.S vaccine in 1045 healthy adults between the ages of 18-55 (NCT04436276 ... vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein ... As of June 2020, a Phase 1/2 clinical trial in adult humans was announced to evaluate the safety, immunogenicity …
Abiraterone
Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Iupac: … (3aS,3bR,7S,9aR,9bS,11aS)-9a,11a-dimethyl-1-(pyridin-3-yl)-3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H, …
Matched Description: … ] and September 2011,[A260880] respectively. ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... [L40968, L40193, L47740, L47745] As abiraterone has poor oral bioavailability and is susceptible to …
Matched Salts cas: … 154229-18-2 …
Matched Categories: … niraparib and abiraterone ... abiraterone and prednisolone ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Description: … ] and September 2011,[A260880] respectively. ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... [L40968, L40193, L47740, L47745] As abiraterone has poor oral bioavailability and is susceptible to …
Matched Salts cas: … 154229-18-2 …
Matched Categories: … niraparib and abiraterone ... abiraterone and prednisolone ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Lutetium Lu-177 vipivotide tetraxetan
Lutetium Lu-177 vipivotide tetraxetan is a radioligand therapeutic agent. It consists of a radionuclide, lutetium Lu-177, linked to a moiety that binds to PSMA, a transmembrane protein that is expressed in prostate cancer. Lutetium Lu-177 vipivotide tetraxetan was first approved by the FDA on March 23, 2022 as a treatment...
Approved
Matched Iupac: … (177Lu)lutetium(3+) 2-[4,7-bis(carboxylatomethyl)-10-[({[(1r,4r)-4-{[(1S)-1-{[(5S)-5-carboxy-5-({[(1S ... -(naphthalen-2-yl)ethyl]carbamoyl}cyclohexyl]methyl}carbamoyl)methyl]-1,4,7,10-tetraazacyclododecan-1- …
Matched Description: … [L41290] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended ... consists of a radionuclide, [lutetium Lu-177], linked to a moiety that binds to PSMA, a transmembrane protein ... tetraxetan was first approved by the FDA on March 23, 2022 as a treatment for prostate-specific membrane antigen–positive …
Matched Products: … 1 Pluvicto …
Matched Description: … [L41290] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended ... consists of a radionuclide, [lutetium Lu-177], linked to a moiety that binds to PSMA, a transmembrane protein ... tetraxetan was first approved by the FDA on March 23, 2022 as a treatment for prostate-specific membrane antigen–positive …
Matched Products: … 1 Pluvicto …
Tositumomab
Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).
Approved
Investigational
Matched Description: … Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 76 - 100 of 192 in total