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Displaying drugs 101 - 125 of 890 in total
Isotretinoin
Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the...
Approved
Matched Products: … TINOIN-10 ... ซอฟเทน 10 ... ISONIN 10 …
Periciazine
Periciazine is a phenothiazine of the piperidine group. It has been shown to reduce pathologic arousal and affective tension in some psychotic patients, while the symptoms of abnormal mental integration are relatively unaffected. It is a sedative phenothiazine with weak antipsychotic properties. It also has adrenolytic, anticholinergic, metabolic and endocrine...
Approved
Investigational
Matched Synonyms: … 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine ... 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine ... 10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile …
Matched Iupac: … 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile …
Matched Iupac: … 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile …
Docetaxel
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Synonyms: … N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol ... N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel …
Matched Iupac: … tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1,9,12-trihydroxy-10,14,17,17-tetramethyl-11 …
Matched Products: … HOSPIRA DOCETAXEL INJECTION (10 MG/ML) ... Docetaxel Ebewe 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung ... SANTAX 20MG/2ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN FLAKON, 10 ADET …
Matched Iupac: … tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1,9,12-trihydroxy-10,14,17,17-tetramethyl-11 …
Matched Products: … HOSPIRA DOCETAXEL INJECTION (10 MG/ML) ... Docetaxel Ebewe 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung ... SANTAX 20MG/2ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN FLAKON, 10 ADET …
Gadoteridol
Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine, and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or those thought to disrupt the normal blood-brain barrier.[A263076,A263081,L49871] It was 1 of the 3 macrocyclic gadolinium-based contrast agents (GBCAs)...
Approved
Investigational
Matched Synonyms: … gadolinium 2,2',2''-[10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetate …
Matched Iupac: … gadolinium(3+) 2-[4,7-bis(carboxylatomethyl)-10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecan-1-yl] …
Matched Iupac: … gadolinium(3+) 2-[4,7-bis(carboxylatomethyl)-10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecan-1-yl] …
Idarubicin
An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Products: … ZAVEDOS CS INJECTION 10 mg/10 ml ... X 10 MG ... Idarubicin Accord 10 mg/10 ml Injektionslösung …
Prednisone acetate
Approved
Experimental
Investigational
Estradiol
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Synonyms: … (17β)-estra-1,3,5(10)-triene-3,17-diol ... 17β-estra-1,3,5(10)-triene-3,17-diol …
Matched Mixtures name: … FEMOSTON 1/10 ... FEMOSTON 1/10 ... Femoston 2/10 Tablet …
Matched Products: … Vagifem 10 ... PMS-estradiol 10 ... Rewellfem 10 Mikrogramm Vaginaltabletten …
Matched Mixtures name: … FEMOSTON 1/10 ... FEMOSTON 1/10 ... Femoston 2/10 Tablet …
Matched Products: … Vagifem 10 ... PMS-estradiol 10 ... Rewellfem 10 Mikrogramm Vaginaltabletten …
Iron isomaltoside 1000
Iron isomaltoside 1000 is under investigation in Iron Deficiency Anaemia. Iron isomaltoside 1000 has been investigated for the treatment and basic science of Anemia, Gastric Cancer, Esophageal Cancer, Chronic Kidney Disease, and Anemia, Iron-Deficiency, among others.
Approved
Investigational
Dronabinol
Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, which results in the well-known effects of smoking cannabis such as increased appetite, reduced pain, and...
Approved
Illicit
Quetiapine
Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high...
Approved
Matched Synonyms: … 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol …
Matched Iupac: … 2-[2-(4-{2-thia-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-10-yl}piperazin-1-yl …
Matched Products: … SEROQUEL XR 150 MG UZATILMIŞ SALIMLI TABLET, 10 TABLET …
Matched Iupac: … 2-[2-(4-{2-thia-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-10-yl}piperazin-1-yl …
Matched Products: … SEROQUEL XR 150 MG UZATILMIŞ SALIMLI TABLET, 10 TABLET …
Aldesleukin
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Products: … Proleukin 18 x 10 6 IE - Pulver zur Herstellung einer Injektions- oder Infusionslösung …
Birch bark extract
Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities. Some of the compounds identified in it include betulin, lupeol, betulinic acid, oleanolic acid, and erythrodiol. Birch bark extract is obtained from the white part of the birch tree bark, and the main species of trees used...
Approved
Experimental
Matched Description: … [L42380] Two oleogel formulations of birch bark extract (Oleogel-S10, 10% of triterpene dry extract in …
Clascoterone
Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. It binds to androgen receptors with high affinity. By competing with androgens for binding to androgen receptors, clascoterone works by blocking the androgen receptor signalling cascades that promote acne pathogenesis, such as sebaceous gland proliferation, excess sebum production, and...
Approved
Investigational
Matched Synonyms: … 11-deoxycortisol 17α-propionate …
Somatrogon
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Methotrexate
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid …
Matched Products: … LANTAREL 10 ... Ebetrexat 10 mg - Tabletten ... MTX 10 HEXAL INJEKT …
Matched Products: … LANTAREL 10 ... Ebetrexat 10 mg - Tabletten ... MTX 10 HEXAL INJEKT …
Lisuride
An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).
Approved
Investigational
Thioridazine
A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed,...
Approved
Withdrawn
Matched Synonyms: … 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine ... 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine …
Matched Iupac: … 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine …
Matched Products: … ไทดาซีน-10 ... ไธโอดิล 10 ... ORİDAZİN 10 MG DRAJE, 30 ADET …
Matched Iupac: … 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine …
Matched Products: … ไทดาซีน-10 ... ไธโอดิล 10 ... ORİDAZİN 10 MG DRAJE, 30 ADET …
Pegademase
Bovine adenosine deaminase derived from bovine intestine that has been extensively pegylated for extended serum half life.
Approved
Matched Synonyms: … (monomethoxypolyethylene glycol succinimidyl) 11-17-adenosine deaminase …
Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 11A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … (3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine ... (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine ... (S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine …
Matched Iupac: … (13),6,8,11-tetraene-11-carboxylic acid ... (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5 …
Matched Products: … INFECUR 500 MG FILM TABLET, 10 ADET ... LEBEL 250 MG FILM TABLET, 10 ADET ... LEVOXIMED 250MG FILM KAPLI TABLET , 10 TABLET …
Matched Iupac: … (13),6,8,11-tetraene-11-carboxylic acid ... (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5 …
Matched Products: … INFECUR 500 MG FILM TABLET, 10 ADET ... LEBEL 250 MG FILM TABLET, 10 ADET ... LEVOXIMED 250MG FILM KAPLI TABLET , 10 TABLET …
Estriol
A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During pregnancy, large amount of estriol is produced by the placenta. Isomers with inversion of the hydroxyl group or groups are called epiestriol. Though estriol is...
Approved
Investigational
Vet approved
Matched Synonyms: … (16α,17β)-estra-1,3,5(10)-triene-3,16,17-triol ... 1,3,5(10)-Estratriene-3,16-alpha,17beta-triol …
Pralatrexate
Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … 10-Propargyl-10-deazaaminopterin …
Tocofersolan
D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis . Cholestasis is the reduction or stoppage of bile flow, either to impaired secretion by hepatocytes (liver cells) or obstruction , .
Tocofersolan is a...
Approved
Displaying drugs 101 - 125 of 890 in total