Displaying drugs 126 - 150 of 2597 in total
Doxorubicin
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Synonyms: … (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino ... (8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy …
Matched Description: … terminates with a primary alcohol group compared to the methyl group of daunorubicin. ... ’s and Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Anthracyclines and Related Substances ... Cytotoxic Antibiotics and Related Substances ... Antineoplastic Agents ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index …
Matched Products: … DOXORRUBICINA CLORHIDRATO 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. …
Matched Description: … terminates with a primary alcohol group compared to the methyl group of daunorubicin. ... ’s and Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Anthracyclines and Related Substances ... Cytotoxic Antibiotics and Related Substances ... Antineoplastic Agents ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index …
Matched Products: … DOXORRUBICINA CLORHIDRATO 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. …
Zilucoplan
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … -ASPARTYL-3-METHYL-L-VALYL-L-TYROSYL-3-(1H-PYRROLO(2,3-B)PYRIDIN-3-YL)-L-ALANYL-L-.ALPHA. ... -ASPARTYL-3-METHYL- ... -GLUTAMYL-L-TYROSYL-L-PROLYL-(2S)-2-CYCLOHEXYLGLYCYL-N6-(3 …
Matched Iupac: … carbamimidamidopropyl)-5-(2-carboxyethyl)-22-acetamido-3,6,9,12,16,23-hexaoxo-2-(propan-2-yl)-1,4,7,10,13,17 ... )propanamido]-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanamido]-4-carboxybutanamido]-3-(4-hydroxyphenyl)propanoyl ... -hexaazacyclotricosan-14-yl]-N-methylformamido}-3-carboxypropanamido]-3,3-dimethylbutanamido]-3-(4-hydroxyphenyl ... -2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11-benzyl-8-(3- …
Matched Description: … It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein ... Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. …
Matched Categories: … Complement Inactivating Agents ... Amino Acids, Peptides, and Proteins …
Matched Iupac: … carbamimidamidopropyl)-5-(2-carboxyethyl)-22-acetamido-3,6,9,12,16,23-hexaoxo-2-(propan-2-yl)-1,4,7,10,13,17 ... )propanamido]-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}propanamido]-4-carboxybutanamido]-3-(4-hydroxyphenyl)propanoyl ... -hexaazacyclotricosan-14-yl]-N-methylformamido}-3-carboxypropanamido]-3,3-dimethylbutanamido]-3-(4-hydroxyphenyl ... -2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11-benzyl-8-(3- …
Matched Description: … It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein ... Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. …
Matched Categories: … Complement Inactivating Agents ... Amino Acids, Peptides, and Proteins …
Fluconazole
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Description: … superficial fungal infections in a variety of tissues. ... This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. ... Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and …
Matched Categories: … Antifungal Agents ... Anti-Infective Agents ... Imidazole and Triazole Derivatives ... Triazole and tetrazole derivatives ... Agents causing hyperkalemia …
Matched Products: … CANDIDIN 50 MG KAPSÜL, 3 ADET …
Matched Categories: … Antifungal Agents ... Anti-Infective Agents ... Imidazole and Triazole Derivatives ... Triazole and tetrazole derivatives ... Agents causing hyperkalemia …
Matched Products: … CANDIDIN 50 MG KAPSÜL, 3 ADET …
Ibrutinib
Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Synonyms: … 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Iupac: … 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Description: … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies ... Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase ... [A32299] Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in November 2013 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Antineoplastic Agents ... Myelosuppressive Agents ... Immunosuppressive Agents …
Matched Iupac: … 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Description: … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies ... Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase ... [A32299] Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in November 2013 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Antineoplastic Agents ... Myelosuppressive Agents ... Immunosuppressive Agents …
Diflunisal
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Synonyms: … 2',4'-difluoro-4-hydroxy-3-biphenylcarboxylic acid …
Matched Iupac: … 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid …
Matched Description: … Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic ... rheumatoid arthritis and osteoarthritis. ... Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. …
Matched Categories: … Salicylic Acid and Derivatives ... Antirheumatic Agents ... Nephrotoxic agents ... Agents causing hyperkalemia ... Anti-Inflammatory Agents …
Matched Iupac: … 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid …
Matched Description: … Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic ... rheumatoid arthritis and osteoarthritis. ... Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. …
Matched Categories: … Salicylic Acid and Derivatives ... Antirheumatic Agents ... Nephrotoxic agents ... Agents causing hyperkalemia ... Anti-Inflammatory Agents …
Flucloxacillin
Antibiotic analog of cloxacillin.
Approved
Investigational
Matched Synonyms: … 3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin ... (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Estradiol cypionate
Estradiol Cypionate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol cypionate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Iupac: … -1-yl 3-cyclopentylpropanoate ... (1S,3aS,3bR,9bS,11aS)-7-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren …
Matched Description: … Because of the difference in potency between estradiol and estrone, menopause (and a change in primary ... a chance to enter systemic circulation and exert its estrogenic effects [A12102]. ... Estradiol Cypionate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously …
Matched Mixtures name: … Truemed Group LLC …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Contraceptive Agents, Female ... Contraceptive Agents, Hormonal ... Reproductive Control Agents …
Matched Description: … Because of the difference in potency between estradiol and estrone, menopause (and a change in primary ... a chance to enter systemic circulation and exert its estrogenic effects [A12102]. ... Estradiol Cypionate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously …
Matched Mixtures name: … Truemed Group LLC …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Contraceptive Agents, Female ... Contraceptive Agents, Hormonal ... Reproductive Control Agents …
Triclocarban
Triclocarban, with the chemical formula C13H9Cl3N2O is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer...
Approved
Matched Synonyms: … 1-(3',4'-dichlorophenyl)-3-(4'-chlorophenyl)urea …
Matched Iupac: … 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea …
Matched Description: … It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products …
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Local …
Matched Iupac: … 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea …
Matched Description: … It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products …
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Local …
Olopatadine
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Iupac: … 2-[(2Z)-2-[3-(dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen …
Matched Description: … Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating ... It is a structural analog of [doxepin], which has a minimal anti-allergic activity. ... seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Decongestants and Antiallergics ... Anti-Allergic Agents ... Histamine Agents ... Anti-Inflammatory Agents …
Matched Products: … OLO-A-DAY ... Pataday Twice A Day Relief ... Eye Allergy Itch and Redness Relief …
Matched Description: … Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating ... It is a structural analog of [doxepin], which has a minimal anti-allergic activity. ... seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Decongestants and Antiallergics ... Anti-Allergic Agents ... Histamine Agents ... Anti-Inflammatory Agents …
Matched Products: … OLO-A-DAY ... Pataday Twice A Day Relief ... Eye Allergy Itch and Redness Relief …
Zalcitabine
A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is...
Approved
Investigational
Matched Synonyms: … 2',3'-Dideoxycytidine …
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by ... a hydrogen. ... This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... Anti-HIV Agents ... Antiviral Agents ... Anti-Infective Agents …
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by ... a hydrogen. ... This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... Anti-HIV Agents ... Antiviral Agents ... Anti-Infective Agents …
Nintedanib
Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC).[L8453,L8459] It was first approved for use in the United States in 2014. Within the spectrum of idiopathic pulmonary fibrosis treatment options, nintedanib is currently one...
Approved
Matched Synonyms: … methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3 …
Matched Iupac: … methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2- …
Matched Description: … indicated for the condition (the other being [Pirfenidone]) and as such is used as a first-line treatment ... Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic ... [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Antifibrotic Agents ... Antineoplastic Agents …
Matched Iupac: … methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2- …
Matched Description: … indicated for the condition (the other being [Pirfenidone]) and as such is used as a first-line treatment ... Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic ... [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Antifibrotic Agents ... Antineoplastic Agents …
Artesunate
Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Description: … [L890] Artesunate was developed out of a need for a more hydrophilic derivative of [artemisinin]. …
Matched Categories: … Antiviral Agents ... Anti-Infective Agents ... Antiparasitic Agents ... Antineoplastic Agents ... Antiplatyhelmintic Agents …
Matched Categories: … Antiviral Agents ... Anti-Infective Agents ... Antiparasitic Agents ... Antineoplastic Agents ... Antiplatyhelmintic Agents …
Penicillamine
Penicillamine is a pharmaceutical of the chelator class. The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine). It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties.
Approved
Matched Synonyms: … (S)-2-amino-3-mercapto-3-methylbutanoic acid ... 3-mercapto-D-valine …
Matched Iupac: … (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid …
Matched Description: … Penicillamine is a pharmaceutical of the chelator class. …
Matched Categories: … Penicillamine and Similar Agents ... Compounds used in a research, industrial, or household setting ... Amino Acids, Peptides, and Proteins ... Antiinflammatory and Antirheumatic Products ... Chelating Agents …
Matched Iupac: … (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid …
Matched Description: … Penicillamine is a pharmaceutical of the chelator class. …
Matched Categories: … Penicillamine and Similar Agents ... Compounds used in a research, industrial, or household setting ... Amino Acids, Peptides, and Proteins ... Antiinflammatory and Antirheumatic Products ... Chelating Agents …
Avelumab
Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. Avelumab was first approved by the FDA on March 23, 2017. On September 18 and December 18 of the same year,...
Approved
Investigational
Matched Description: … Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) ... ] and Health Canada,[L48171] respectively. ... to block its interaction with its receptors found on T cells and antigen-presenting cells. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Antineoplastic Agents ... Amino Acids, Peptides, and Proteins ... Antineoplastic Agents, Immunological ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Antineoplastic Agents ... Amino Acids, Peptides, and Proteins ... Antineoplastic Agents, Immunological ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Tapinarof
Tapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis. It is available as a topical cream to be applied to the affected area once daily.[L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) produced in Photorhabdus luminescens, a gram-negative bacillus that...
Approved
Investigational
Matched Description: … It is available as a topical cream to be applied to the affected area once daily. ... Tapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment ... [L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) …
Trazodone
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Synonyms: … 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one …
Matched Iupac: … 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one …
Matched Description: … , distinguishing it from other antidepressants that cover a narrow range of neurotransmitters. ... [T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms ... , or insomnia, which are commonly associated with SSRI and SNRI therapy. …
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Triazolopyridine ... Antidepressive Agents, Second-Generation ... Antidepressive Agents Indicated for Depression ... Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Iupac: … 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one …
Matched Description: … , distinguishing it from other antidepressants that cover a narrow range of neurotransmitters. ... [T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms ... , or insomnia, which are commonly associated with SSRI and SNRI therapy. …
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Triazolopyridine ... Antidepressive Agents, Second-Generation ... Antidepressive Agents Indicated for Depression ... Serotonin antagonist and reuptake inhibitors (SARIs) …
Etanercept
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … ), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA). ... Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell ... [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antirheumatic Agents ... Anti-Inflammatory Agents ... Agents reducing cytokine levels ... Immunosuppressive Agents …
Matched Products: … Truemed Group LLC ... Enbrel Solution for Injection in a Pre-filled Pen 50mg ... Enbrel Solution for Injection in a Pre-filled Syringe 50mg …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antirheumatic Agents ... Anti-Inflammatory Agents ... Agents reducing cytokine levels ... Immunosuppressive Agents …
Matched Products: … Truemed Group LLC ... Enbrel Solution for Injection in a Pre-filled Pen 50mg ... Enbrel Solution for Injection in a Pre-filled Syringe 50mg …
Perindopril
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor ... Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of …
Matched Salts cas: … 1258291-80-3 …
Matched Categories: … Hypotensive Agents ... Cardiovascular Agents ... Antihypertensive Agents ... Agents causing angioedema ... Lipid Modifying Agents …
Matched Salts cas: … 1258291-80-3 …
Matched Categories: … Hypotensive Agents ... Cardiovascular Agents ... Antihypertensive Agents ... Agents causing angioedema ... Lipid Modifying Agents …
Methylergometrine
A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Approved
Matched Description: … A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed) …
Matched Categories: … Uterotonic agents ... Agents that produce hypertension ... Reproductive Control Agents ... Ergot Alkaloids and Derivatives ... methylergometrine and oxytocin …
Matched Products: … UTERJIN 0,2 MG IM 3 AMPUL ... METILER 0,2 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... UTESEL 0,2 MG/ML IM ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 3 AMPUL …
Matched Categories: … Uterotonic agents ... Agents that produce hypertension ... Reproductive Control Agents ... Ergot Alkaloids and Derivatives ... methylergometrine and oxytocin …
Matched Products: … UTERJIN 0,2 MG IM 3 AMPUL ... METILER 0,2 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... UTESEL 0,2 MG/ML IM ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 3 AMPUL …
Calcitriol
Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamin D3. It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to DB00169 (vitamin D3)...
Approved
Nutraceutical
Matched Description: … D3. ... Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred ... Administered orally and intravenously, calcitriol is commonly used as a medication in the treatment of …
Matched Categories: … Skin and Mucous Membrane Agents ... Calcium-Regulating Hormones and Agents ... Bone Density Conservation Agents ... Alimentary Tract and Metabolism ... Vitamin D and Analogues …
Matched Products: … SILKIS OINTMENT 3 mcg/g …
Matched Categories: … Skin and Mucous Membrane Agents ... Calcium-Regulating Hormones and Agents ... Bone Density Conservation Agents ... Alimentary Tract and Metabolism ... Vitamin D and Analogues …
Matched Products: … SILKIS OINTMENT 3 mcg/g …
Interferon alfa-n3
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Matched Description: … including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD). ... Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms …
Matched Categories: … Immunosuppressive Agents ... Myelosuppressive Agents ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Immunosuppressive Agents ... Myelosuppressive Agents ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Tolcapone
Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.
Approved
Withdrawn
Matched Iupac: … 5-(4-methylbenzoyl)-3-nitrobenzene-1,2-diol …
Matched Description: … Tolcapone is associated with a risk of hepatotoxicity. ... It is a yellow, odorless, non-hygroscopic, crystalline compound. ... Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). …
Matched Categories: … Dopamine Agents ... Anti-Dyskinesia Agents ... Hypotensive Agents ... Central Nervous System Agents …
Matched Description: … Tolcapone is associated with a risk of hepatotoxicity. ... It is a yellow, odorless, non-hygroscopic, crystalline compound. ... Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). …
Matched Categories: … Dopamine Agents ... Anti-Dyskinesia Agents ... Hypotensive Agents ... Central Nervous System Agents …
Chlorambucil
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Description: … and nonmalignant diseases. ... A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant ... Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Antineoplastic Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Agents that reduce seizure threshold …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Antineoplastic Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Agents that reduce seizure threshold …
Thiethylperazine
A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
Approved
Withdrawn
Matched Synonyms: … 2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Iupac: … 2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Description: … anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. ... A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Autonomic Agents ... Dopamine Agents ... Antipsychotic Agents ... Neurotoxic agents …
Matched Iupac: … 2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Matched Description: … anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. ... A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Autonomic Agents ... Dopamine Agents ... Antipsychotic Agents ... Neurotoxic agents …
Ethynodiol diacetate
A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that has never been...
Approved
Matched Iupac: … -7-(acetyloxy)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that ... A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive ... Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually …
Matched Mixtures name: … Ethynodiol Diacetate and Ethinyl Estradiol ... Ethynodiol Diacetate and Ethinyl Estradiol …
Matched Categories: … Genito Urinary System and Sex Hormones ... Contraceptive Agents, Female ... Sex Hormones and Modulators of the Genital System ... Combination Contraceptives (with Estrogen and derivatives) ... Contraceptive Agents, Hormonal …
Matched Description: … being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that ... A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive ... Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually …
Matched Mixtures name: … Ethynodiol Diacetate and Ethinyl Estradiol ... Ethynodiol Diacetate and Ethinyl Estradiol …
Matched Categories: … Genito Urinary System and Sex Hormones ... Contraceptive Agents, Female ... Sex Hormones and Modulators of the Genital System ... Combination Contraceptives (with Estrogen and derivatives) ... Contraceptive Agents, Hormonal …
Displaying drugs 126 - 150 of 2597 in total