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Displaying drugs 151 - 175 of 1155 in total

TPX-4589

TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and …

Pelargonium sidoides root

Experimental
Matched Synonyms: … South African geranium root ... Pelargonium sidoides extract, root ... Pelargonium sidoides root extract …
Matched Name: … Pelargonium sidoides root …

Goflikicept

Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein ... Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and …
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …

Rehmannia glutinosa root

Rehmannia glutinosa root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Di Huang Root ... Rehmannia Root ... Leuzea Uniflora Root …
Matched Name: … Rehmannia glutinosa root …
Matched Description: … Rehmannia glutinosa root is a plant/plant extract used in some OTC (over-the-counter) products. …

Spanlecortemlocel

Investigational
Matched Synonyms: … ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED HEMATOPOIETIC STEM AND PROGENITOR CELLS MGTA-456 ... Allogeneic umbilical cord blood (UCB) cell therapy product consisting of two cell fractions (CD34 enriched and …

Aldafermin

Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study in Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3)).
Investigational
Matched Synonyms: … coli ... ala8>ser,gly9>ser,his11>leu) fibroblast growth factor 19 (human fgf19) (5-194)-peptide, produced in escherichia …
Matched Description: … Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability ... Double-blind, Placebo-controlled, Multi-center Study in Subjects With Nonalcoholic Steatohepatitis and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Omalizumab

Omalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). IgE promotes the release of inflammatory mediators from mast cells and basophils during allergic and inflammatory reactions. By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its...
Approved
Investigational
Matched Description: … By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding ... , and asthma. ... and inflammatory reactions. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xolair 75mg Powder and Solvent for Solution for Injection ... XOLAIR 150MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Xolair 150mg Powder and Solvent for Solution for Injection …

Orris

Orris allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Iris x germanica root ... Iris germanica var. florentina root …
Matched Products: … Orris Root …

Anbenitamab

Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 …

Polygala tenuifolia root

Experimental
Matched Synonyms: … Polygala root ... Polygala tenuifolia root ... Thinleaf milkwort root …
Matched Name: … Polygala tenuifolia root …

Glycyrrhiza glabra

Glycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Gan Cao Root ... Cultivated Licorice Root ... Yashtimadhu Root …

CVac

Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …

AMG 424

AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 …

NTLA-2002

NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and ... It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce …

Histamine

A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Approved
Investigational
Matched Description: … a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and ... A depressor amine derived by enzymatic decarboxylation of histidine. …
Matched Mixtures name: … Histamine DHCl 0.10 Percent and Menthol 2 Percent …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Hand and Wrist Pain Cream ... Australian Dream Hand and Wrist Pain ... MINTED LEAF Odorless Histamine DHCl Pain Relief and Hemp Extract …

Hydrocodone

Hydrocodone is a synthetic opioid derivative of codeine. It is commonly used in combination with acetaminophen to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by dextromethorphan in current cough and cold formulations. Hydrocodone's more potent metabolite, hydromorphone...
Approved
Illicit
Investigational
Matched Description: … [dextromethorphan] in current cough and cold formulations. ... Hydrocodone's more potent metabolite, [hydromorphone] has also found wide use as an analgesic and is ... Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by …
Matched Mixtures name: … Hydrocodone Bit/apap ... Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate and Acetaminophen …
Matched Categories: … Cough and Cold Preparations ... hydrocodone and ibuprofen ... hydrocodone and paracetamol ... Opium Alkaloids and Derivatives …
Matched Products: … Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate And Acetaminophen …

Von Willebrand factor human

The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Description: … It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood ... It was first approved by the FDA in 2015. ... and hemophilia A. …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Synthetic camphor

Approved
Experimental
Matched Mixtures name: … Up and Up Cold Sore Treatment ... Bio-mega ... Bio-ice …
Matched Products: … Soothe and Move Pain Relief Cream ... Arthritis and Joint Pain Relief Thayers ... Weeks and Leo Medicated Vaporizing Steam …

Antihemophilic factor human

Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Description: … Factor VIII, but does not contain the B-domain, which has no known biological function and [DB11607] ... The complex was developed by CSL Behring or Baxter Healthcare Corporation and approved in the 90s. ... Antihemophilic factor human is approved by the Food and Drug Administration for use in hemophilia A ( …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... Octanate 500IU Powder and Solvent for Solution for Injection …

Ephedra sinica root

Ephedra is an alkaloid chemical compound traditionally obtained from the plant Ephedra sinica. The sale of ephedra-containing supplements intended to increase muscle weight or promote weight loss was banned in the United States in 2004 due to the risk for adverse effects and a lack of evidence for clinical effectiveness....
Nutraceutical
Matched Synonyms: … Cao ma huang root ... Hemp yellow root ... Ephedra sinica root …
Matched Name: … Ephedra sinica root …
Matched Description: … or promote weight loss was banned in the United States in 2004 due to the risk for adverse effects and …
Matched Mixtures name: … Herbal Cold and Flu Formula - Tab …
Matched Categories: … Herbs and Natural Products ... Alpha-and Beta-adrenergic Agonists …

Atacicept

Atacicept is a recombinant fusion protein combined with the extracellular ligand binding portion of TACI.
Investigational
Matched Synonyms: … Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein ( …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Loperamide

Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Description: … withdrawal symptoms and to induce euphoria. ... [L42785] The drug was first synthesized in 1969 and used medically in 1976. ... [A6249] Due to pharmacological properties, loperamide has been misused and abused to self-manage opioid …
Matched Mixtures name: … Doc in the Box All Day Supply ... Anti Diarrheal and Anti Gas ... Loperamide Hydrochloride and Simethicone …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up anti diarrheal ... Berkley and Jensen Anti Diarrheal ... Foster and Thrive Anti-diarrheal …

Sodium fluorophosphate

Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Approved
Matched Mixtures name: … Mentadent Specialty Whitening Toothpaste and Polishing ... Hawaiian Airline EC with Colgate Toothbrush and Sun ... Strings Bag …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Hello Bye Bye Bacteria Fluoride ... Bee Smart ... Crest Kids Advanced Color Changing …

Cabazitaxel

Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Description: … [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 ... It was first approved by the FDA on June 17, 2010. ... A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) ... Cabazred 60mg/1.5ml Concentrate And Solvent For Solution For Infusion …

Chloroxylenol

Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Description: … disinfection and surgical instruments. ... The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell ... It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. …
Matched Mixtures name: … Cortane-B ... D-COL Personal Hygiene Convenience kit ... Cortaine -B Aqueous …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants …
Matched Products: … Ban-Aid ... Clear Bac ... Bex Foam …
Displaying drugs 151 - 175 of 1155 in total