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Identification
NameGabapentin
Accession NumberDB00996  (APRD00015)
TypeSmall Molecule
GroupsApproved, Investigational
Description

Gabapentin (brand name Neurontin) is a medication originally developed for the treatment of epilepsy. Presently, gabapentin is widely used to relieve pain, especially neuropathic pain. Gabapentin is well tolerated in most patients, has a relatively mild side-effect profile, and passes through the body unmetabolized.

Structure
Thumb
Synonyms
1-(Aminomethyl)cyclohexaneacetic acid
Gabapentin GR
Gabapentina
Gabapentine
Gabapentino
Gabapentinum
Gabapetin
Neurontin
External Identifiers Not Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Act Gabapentincapsule400 mgoralActavis Pharma Company2005-02-16Not applicableCanada
Act Gabapentincapsule300 mgoralActavis Pharma Company2005-02-16Not applicableCanada
Act Gabapentincapsule100 mgoralActavis Pharma Company2005-02-16Not applicableCanada
Auro-gabapentincapsule300 mgoralAuro Pharma Inc2011-06-15Not applicableCanada
Auro-gabapentincapsule400 mgoralAuro Pharma Inc2011-06-15Not applicableCanada
Auro-gabapentincapsule100 mgoralAuro Pharma Inc2011-06-15Not applicableCanada
Auro-gabapentin Tabletstablet800 mgoralAuro Pharma IncNot applicableNot applicableCanada
Auro-gabapentin Tabletstablet600 mgoralAuro Pharma IncNot applicableNot applicableCanada
Bci Gabapentincapsule300 mgoralBaker Cummins IncNot applicableNot applicableCanada
Dom-gabapentincapsule400 mgoralDominion Pharmacal2002-03-11Not applicableCanada
Dom-gabapentintablet800 mgoralDominion PharmacalNot applicableNot applicableCanada
Dom-gabapentincapsule300 mgoralDominion Pharmacal2002-03-11Not applicableCanada
Dom-gabapentintablet600 mgoralDominion PharmacalNot applicableNot applicableCanada
Dom-gabapentincapsule100 mgoralDominion Pharmacal2002-03-11Not applicableCanada
FanatrexkitoralCalifornia Pharmaceuticals, Llc2016-01-012016-04-05Us
FanatrexkitoralCalifornia Pharmaceuticals Llc2010-05-152016-04-05Us
Gabapentinsuspension250 mg/5mLoralGreenstone LLC2011-03-292016-04-05Us
Gabapentincapsule100 mg/1oralGreenstone LLC1993-12-302016-04-05Us
Gabapentintablet800 mgoralSivem Pharmaceuticals Ulc2012-06-26Not applicableCanada
Gabapentincapsule400 mgoralSorres Pharma Inc2009-02-262014-06-20Canada
Gabapentincapsule400 mgoralOmni Laboratories Division, Warner Lambert Canada Inc.Not applicableNot applicableCanada
Gabapentintablet, film coated800 mg/1oralGreenstone LLC1998-10-092016-04-05Us
Gabapentintablet600 mgoralSivem Pharmaceuticals Ulc2012-06-26Not applicableCanada
Gabapentincapsule300 mgoralSorres Pharma Inc2009-02-262014-06-20Canada
Gabapentincapsule400 mgoralApotex IncNot applicableNot applicableCanada
Gabapentincapsule100 mgoralSorres Pharma Inc2009-02-262014-06-20Canada
Gabapentincapsule400 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Gabapentincapsule100 mgoralApotex IncNot applicableNot applicableCanada
Gabapentincapsule300 mgoralOmni Laboratories Division, Warner Lambert Canada Inc.Not applicableNot applicableCanada
Gabapentintablet, film coated600 mg/1oralGreenstone LLC1998-10-092016-04-05Us
Gabapentincapsule300 mgoralGenpharm Ulc2006-01-172009-02-17Canada
Gabapentincapsule300 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Gabapentincapsule300 mgoralApotex IncNot applicableNot applicableCanada
Gabapentincapsule100 mgoralOmni Laboratories Division, Warner Lambert Canada Inc.Not applicableNot applicableCanada
Gabapentincapsule400 mgoralSivem Pharmaceuticals Ulc2003-01-07Not applicableCanada
Gabapentincapsule100 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Gabapentintablet600 mgoralApotex IncNot applicableNot applicableCanada
Gabapentincapsule300 mgoralSivem Pharmaceuticals Ulc2003-01-07Not applicableCanada
Gabapentincapsule400 mgoralSanis Health Inc2010-07-30Not applicableCanada
Gabapentintablet800 mgoralApotex IncNot applicableNot applicableCanada
Gabapentincapsule100 mgoralSivem Pharmaceuticals Ulc2003-01-07Not applicableCanada
Gabapentincapsule300 mgoralSanis Health Inc2010-07-30Not applicableCanada
Gabapentintablet800 mgoralSanis Health Inc2014-09-23Not applicableCanada
Gabapentincapsule400 mg/1oralGreenstone LLC1993-12-302016-04-05Us
Gabapentincapsule100 mgoralSanis Health Inc2010-07-30Not applicableCanada
Gabapentintablet600 mgoralSanis Health Inc2014-09-23Not applicableCanada
Gabapentincapsule300 mg/1oralGreenstone LLC1993-12-302016-04-05Us
Gabapentin Capsulescapsule400 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Gabapentin Capsulescapsule300 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Gabapentin Capsulescapsule100 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Gabapentin Capsules USPcapsule400 mgoralAccord Healthcare Inc2014-06-04Not applicableCanada
Gabapentin Capsules USPcapsule300 mgoralAccord Healthcare Inc2014-06-04Not applicableCanada
Gabapentin Capsules USPcapsule100 mgoralAccord Healthcare Inc2014-06-04Not applicableCanada
Gabapentin Tablets USPtablet (immediate release)600 mgoralGlenmark Pharmaceuticals Canada Inc.2016-04-04Not applicableCanada
Gabapentin Tablets USPtablet800 mgoralAccord Healthcare Inc2012-10-12Not applicableCanada
Gabapentin Tablets USPtablet600 mgoralAccord Healthcare Inc2012-10-12Not applicableCanada
Gabapentin Tablets USPtablet (immediate release)800 mgoralGlenmark Pharmaceuticals Canada Inc.2016-04-04Not applicableCanada
Gd-gabapentintablet800 mgoralGenmed A Division Of Pfizer Canada Inc2011-01-19Not applicableCanada
Gd-gabapentintablet600 mgoralGenmed A Division Of Pfizer Canada Inc2011-01-19Not applicableCanada
Gd-gabapentincapsule400 mgoralGenmed A Division Of Pfizer Canada Inc2011-01-19Not applicableCanada
Gd-gabapentincapsule300 mgoralGenmed A Division Of Pfizer Canada Inc2011-01-19Not applicableCanada
Gd-gabapentincapsule100 mgoralGenmed A Division Of Pfizer Canada Inc2011-01-19Not applicableCanada
Gralisetablet, film coated600 mg/1oralDepomed, Inc.2011-01-282016-04-05Us
Gralisetablet, film coated300 mg/1oralDepomed, Inc.2011-01-282016-04-05Us
Gralisetablet, film coated600 mg/1oralUnit Dose Services2011-01-282016-04-05Us
Gralisetablet, film coated600 mg/1oralbryant ranch prepack2011-01-282016-04-05Us
Gralise Starter PackkitDepomed, Inc.2011-01-282016-04-05Us
Ipg-gabapentincapsule100 mgoralInternational Pharmaceutical Generics LtdNot applicableNot applicableCanada
Ipg-gabapentincapsule400 mgoralInternational Pharmaceutical Generics LtdNot applicableNot applicableCanada
Ipg-gabapentincapsule300 mgoralInternational Pharmaceutical Generics LtdNot applicableNot applicableCanada
Jamp-gabapentincapsule400 mgoralJamp Pharma Corporation2011-09-26Not applicableCanada
Jamp-gabapentincapsule300 mgoralJamp Pharma Corporation2011-09-26Not applicableCanada
Jamp-gabapentincapsule100 mgoralJamp Pharma Corporation2011-09-26Not applicableCanada
Jamp-gabapentin Tabletstablet800 mgoralJamp Pharma Corporation2013-05-01Not applicableCanada
Jamp-gabapentin Tabletstablet600 mgoralJamp Pharma Corporation2013-05-01Not applicableCanada
Mar-gabapentincapsule400 mgoralMarcan Pharmaceuticals Inc2014-01-08Not applicableCanada
Mar-gabapentincapsule300 mgoralMarcan Pharmaceuticals Inc2014-01-08Not applicableCanada
Mar-gabapentincapsule100 mgoralMarcan Pharmaceuticals Inc2014-01-08Not applicableCanada
Mar-gabapentin Tabstablet600 mgoralMarcan Pharmaceuticals IncNot applicableNot applicableCanada
Mar-gabapentin Tabstablet800 mgoralMarcan Pharmaceuticals IncNot applicableNot applicableCanada
Mint-gabapentincapsule100 mgoralMint Pharmaceuticals IncNot applicableNot applicableCanada
Mint-gabapentincapsule400 mgoralMint Pharmaceuticals IncNot applicableNot applicableCanada
Mint-gabapentincapsule300 mgoralMint Pharmaceuticals IncNot applicableNot applicableCanada
Mylan-gabapentincapsule400 mgoralMylan Pharmaceuticals Ulc2003-11-03Not applicableCanada
Mylan-gabapentincapsule300 mgoralMylan Pharmaceuticals Ulc2003-11-03Not applicableCanada
Mylan-gabapentintablet800 mgoralMylan Pharmaceuticals Ulc2012-11-28Not applicableCanada
Mylan-gabapentincapsule100 mgoralMylan Pharmaceuticals Ulc2003-11-03Not applicableCanada
Mylan-gabapentintablet600 mgoralMylan Pharmaceuticals Ulc2012-11-28Not applicableCanada
Neurontintablet, film coated800 mg/1oralParke Davis Div Of Pfizer Inc1998-10-092016-04-23Us
Neurontincapsule300 mg/1oralCardinal Health1993-12-302016-04-05Us
Neurontinsolution250 mg/5mLoralParke Davis Div Of Pfizer Inc2000-03-022016-04-23Us
Neurontincapsule300 mg/1oralREMEDYREPACK INC.2012-09-172016-04-05Us
Neurontincapsule400 mg/1oralParke Davis Div Of Pfizer Inc1993-12-302016-04-23Us
Neurontincapsule300 mg/1oralParke Davis Div Of Pfizer Inc1993-12-302016-04-23Us
Neurontincapsule100 mg/1oralParke Davis Div Of Pfizer Inc1993-12-302016-04-23Us
Neurontincapsule400 mg/1oralSTAT Rx USA LLC1993-12-302016-04-05Us
Neurontintablet, film coated600 mg/1oralParke Davis Div Of Pfizer Inc1998-10-092016-04-23Us
Neurontin 600mgtablet600 mgoralPfizer Canada Inc2000-05-01Not applicableCanada
Neurontin 800mgtablet800 mgoralPfizer Canada Inc2000-05-01Not applicableCanada
Neurontin Cap 100mgcapsule100 mgoralPfizer Canada Inc1994-12-31Not applicableCanada
Neurontin Cap 300mgcapsule300 mgoralPfizer Canada Inc1994-12-31Not applicableCanada
Neurontin Cap 400mgcapsule400 mgoralPfizer Canada Inc1994-12-31Not applicableCanada
Ntp-gabapentintablet800 mgoralTeva Canada LimitedNot applicableNot applicableCanada
Ntp-gabapentintablet600 mgoralTeva Canada LimitedNot applicableNot applicableCanada
Nu-gabapentin Capsulescapsule100 mgoralNu Pharm IncNot applicableNot applicableCanada
Nu-gabapentin Capsulescapsule400 mgoralNu Pharm IncNot applicableNot applicableCanada
Nu-gabapentin Capsulescapsule300 mgoralNu Pharm IncNot applicableNot applicableCanada
Pendo-gabapentincapsule300 mgoralPendopharm Division Of De Pharmascience IncNot applicableNot applicableCanada
PHL-gabapentintablet800 mgoralPharmel Inc2004-12-02Not applicableCanada
PHL-gabapentintablet600 mgoralPharmel Inc2004-12-02Not applicableCanada
PMS-gabapentintablet800 mgoralPharmascience Inc2004-07-28Not applicableCanada
PMS-gabapentintablet600 mgoralPharmascience Inc2004-07-28Not applicableCanada
PMS-gabapentincapsule400 mgoralPharmascience Inc2001-02-23Not applicableCanada
PMS-gabapentincapsule300 mgoralPharmascience Inc2001-02-23Not applicableCanada
PMS-gabapentincapsule100 mgoralPharmascience Inc2001-02-23Not applicableCanada
Pro-gabapentincapsule300 mgoralPro Doc Limitee2008-10-27Not applicableCanada
Pro-gabapentincapsule100 mgoralPro Doc Limitee2008-10-27Not applicableCanada
Pro-gabapentintablet800 mgoralPro Doc Limitee2008-10-27Not applicableCanada
Pro-gabapentintablet600 mgoralPro Doc Limitee2008-10-27Not applicableCanada
Pro-gabapentincapsule400 mgoralPro Doc Limitee2008-10-27Not applicableCanada
Ran-gabapentincapsule400 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-01-07Not applicableCanada
Ran-gabapentincapsule300 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-01-07Not applicableCanada
Ran-gabapentincapsule100 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-01-07Not applicableCanada
Ratio-gabapentincapsule100 mgoralRatiopharm Inc Division Of Teva Canada Limited2004-12-082014-09-19Canada
Ratio-gabapentintablet800 mgoralRatiopharm Inc Division Of Teva Canada Limited2004-12-082014-09-19Canada
Ratio-gabapentintablet600 mgoralRatiopharm Inc Division Of Teva Canada Limited2004-12-082014-09-19Canada
Ratio-gabapentincapsule400 mgoralRatiopharm Inc Division Of Teva Canada Limited2004-12-082014-09-19Canada
Ratio-gabapentincapsule300 mgoralRatiopharm Inc Division Of Teva Canada Limited2004-12-082014-09-19Canada
Riva-gabapentintablet600 mgoralLaboratoire Riva Inc2004-12-03Not applicableCanada
Riva-gabapentincapsule400 mgoralLaboratoire Riva Inc2004-03-25Not applicableCanada
Riva-gabapentincapsule300 mgoralLaboratoire Riva Inc2004-03-25Not applicableCanada
Riva-gabapentincapsule100 mgoralLaboratoire Riva Inc2004-03-25Not applicableCanada
Riva-gabapentintablet800 mgoralLaboratoire Riva Inc2004-12-03Not applicableCanada
Taro-gabapentincapsule400 mgoralTaro Pharmaceuticals IncNot applicableNot applicableCanada
Taro-gabapentincapsule300 mgoralTaro Pharmaceuticals IncNot applicableNot applicableCanada
Taro-gabapentincapsule100 mgoralTaro Pharmaceuticals IncNot applicableNot applicableCanada
Teva-gabapentincapsule100 mgoralTeva Canada Limited2002-06-21Not applicableCanada
Teva-gabapentincapsule300 mgoralTeva Canada Limited2002-06-21Not applicableCanada
Teva-gabapentintablet800 mgoralTeva Canada Limited2003-06-30Not applicableCanada
Teva-gabapentintablet600 mgoralTeva Canada Limited2003-11-19Not applicableCanada
Teva-gabapentincapsule400 mgoralTeva Canada Limited2002-06-21Not applicableCanada
Van-gabapentintablet800 mgoralVanc Pharmaceuticals Inc2015-07-07Not applicableCanada
Van-gabapentintablet600 mgoralVanc Pharmaceuticals Inc2015-07-07Not applicableCanada
Van-gabapentincapsule400 mgoralVanc Pharmaceuticals Inc2015-06-10Not applicableCanada
Van-gabapentincapsule300 mgoralVanc Pharmaceuticals Inc2015-06-10Not applicableCanada
Van-gabapentincapsule100 mgoralVanc Pharmaceuticals Inc2015-06-10Not applicableCanada
Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Apo-gabapentintablet800 mgoralApotex Inc2008-06-04Not applicableCanada
Apo-gabapentintablet600 mgoralApotex Inc2008-06-04Not applicableCanada
Apo-gabapentin Capsulescapsule400 mgoralApotex Inc2001-08-27Not applicableCanada
Apo-gabapentin Capsulescapsule300 mgoralApotex Inc2001-08-27Not applicableCanada
Apo-gabapentin Capsulescapsule100 mgoralApotex Inc2001-08-27Not applicableCanada
Gabapentincapsule400 mg/1oralRebel Distributors Corp2009-11-242016-04-05Us
Gabapentincapsule100 mg/1oralDepartment Of State Health Services, Pharmacy Branch2011-01-292016-04-05Us
Gabapentintablet, film coated800 mg/1oralSolco healthcare U.S., LLC2014-11-012016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2011-05-192016-04-05Us
Gabapentincapsule100 mg/1oralAphena Pharma Solutions Tennessee, Llc2008-01-312016-04-05Us
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2011-06-072016-04-05Us
Gabapentincapsule100 mg/1oralAv Pak2014-09-152016-03-15Us
Gabapentincapsule400 mg/1oralActavis Pharma, Inc.2014-03-172016-04-05Us
Gabapentincapsule100 mg/1oralTIME CAP LABORATORIES, INC2015-12-302016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2013-05-152016-04-05Us
Gabapentincapsule300 mg/1oralMylan Pharmaceuticals Inc.2011-02-142016-04-23Us
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2011-09-092016-04-05Us
Gabapentincapsule300 mg/1oralUnit Dose Services2010-05-172016-04-05Us
Gabapentintablet, film coated600 mg/1oralActavis Pharma, Inc.2004-02-142016-04-23Us
Gabapentincapsule400 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-242016-04-05Us
Gabapentincapsule300 mg/1oralAv Pak2014-09-152016-04-05Us
Gabapentintablet600 mg/1oralTeva Pharmaceuticals USA Inc2008-07-112016-04-23Us
Gabapentincapsule400 mg/1oralMajor Pharmaceuticals2010-05-102016-04-05Us
Gabapentincapsule100 mg/1oralLucid Pharma Llc2008-01-312016-04-05Us
Gabapentincapsule400 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-03-172016-04-23Us
Gabapentincapsule300 mg/1oralCardinal Health2011-01-292016-04-05Us
Gabapentincapsule100 mg/1oralHikma Pharmaceutical2007-07-092016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2013-05-222016-04-05Us
Gabapentincapsule400 mg/1oralMylan Pharmaceuticals Inc.2011-02-142016-04-23Us
Gabapentincapsule400 mg/1oralCardinal Health2010-05-102016-04-05Us
Gabapentintablet, film coated600 mg/1oralClinical Solutions Wholesale2006-08-242016-04-05Us
Gabapentincapsule100 mg/1oralCardinal Health2014-07-012016-04-05Us
Gabapentintablet, film coated300 mg/1oralApotex Corp.2006-10-102016-04-05Us
Gabapentincapsule300 mg/1oralPhysicians Total Care, Inc.2006-08-292016-04-05Us
Gabapentintablet, film coated600 mg/1oralCardinal Health2014-11-032016-04-05Us
Gabapentincapsule100 mg/1oralCardinal Health2004-04-282016-04-05Us
Gabapentincapsule300 mg/1oralGolden State Medical Supply, Inc.2010-05-172016-04-05Us
Gabapentintablet800 mg/1oralDIRECT RX2015-11-252016-04-05Us
Gabapentincapsule400 mg/1oralCardinal Health2011-01-292016-04-05Us
Gabapentincapsule300 mg/1oralHikma Pharmaceutical2007-07-092016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2015-12-302016-04-05Us
Gabapentincapsule300 mg/1oralRanbaxy Pharmaceuticals Inc.2005-11-022016-04-05Us
Gabapentintablet, film coated400 mg/1oralApotex Corp.2006-10-102016-04-05Us
Gabapentincapsule300 mg/1oralProficient Rx LP2010-05-172016-04-05Us
Gabapentintablet600 mg/1oralTYA Pharmaceuticals2006-04-012016-04-05Us
Gabapentincapsule300 mg/1oralDIRECT RX2014-01-012016-04-05Us
Gabapentincapsule400 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2004-10-042016-04-05Us
Gabapentincapsule300 mg/1oralMed Vantx, Inc.2008-01-312016-04-05Us
Gabapentincapsule400 mg/1oralRanbaxy Pharmaceuticals Inc.2005-11-022016-04-05Us
Gabapentintablet, film coated600 mg/1oralCadila Healthcare Limited2012-10-162016-04-05Us
Gabapentincapsule300 mg/1oralAmerican Health Packaging2014-07-012016-04-05Us
Gabapentincapsule300 mg/1oralTYA Pharmaceuticals2006-08-242016-04-05Us
Gabapentincapsule100 mg/1oralAphena Pharma Solutions Tennessee, Llc2004-10-042016-04-05Us
Gabapentintablet, film coated600 mg/1oralNorth Star Rx Llc2011-10-062016-04-05Us
Gabapentintablet800 mg/1oralPreferred Pharmaceuticals, Inc.2015-01-052016-04-05Us
Gabapentincapsule300 mg/1oralMed Vantx Inc.2011-09-132016-04-05Us
Gabapentincapsule100 mg/1oralActavis Pharma Manufacturing Pvt Ltd. (SOD)2010-01-232016-03-12Us
Gabapentincapsule100 mg/1oralKeltman Pharmaceuticals Inc.2009-12-152016-04-05Us
Gabapentintablet800 mg/1oralCamber Pharmaceuticals, Inc.2012-10-292016-04-05Us
Gabapentintablet, film coated800 mg/1oralExelan Pharmaceuticals Inc.2012-11-022016-04-05Us
Gabapentincapsule300 mg/1oralBlenheim Pharmacal, Inc.2010-08-202016-04-05Us
Gabapentincapsule400 mg/1oralAmerican Health Packaging2014-07-012016-04-05Us
Gabapentincapsule400 mg/1oralRebel Distributors Corp.2008-11-072016-04-05Us
Gabapentintablet, film coated600 mg/1oralMc Kesson Contract Packaging2011-11-092016-04-05Us
Gabapentintablet800 mg/1oralRebel Distributors Corp2011-02-092016-04-05Us
Gabapentincapsule400 mg/1oralScie Gen Pharmaceuticals, Inc.2016-02-182016-04-05Us
Gabapentintablet, film coated800 mg/1oralNorth Star Rx Llc2011-10-062016-04-05Us
Gabapentincapsule400 mg/1oralPreferred Pharmaceuticals, Inc.2014-02-282016-04-05Us
Gabapentincapsule100 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2010-05-172016-04-05Us
Gabapentincapsule400 mg/1oralAvera Mc Kennan Hospital2015-03-022016-04-05Us
Gabapentincapsule100 mg/1oralAphena Pharma Solutions Tennessee, Inc.2010-05-172016-04-05Us
Gabapentincapsule100 mg/1oralAidarex Pharmaceuticals LLC2009-11-242016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2016-01-082016-04-05Us
Gabapentintablet600 mg/1oralSTAT Rx USA LLC2009-06-092016-04-05Us
Gabapentincapsule300 mg/1oralActavis Pharma, Inc.2010-01-232016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2013-02-082016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2012-09-202016-04-05Us
Gabapentincapsule100 mg/1oralMylan Pharmaceuticals Inc.2011-02-142016-04-23Us
Gabapentincapsule100 mg/1oralUnit Dose Services2009-11-242016-04-05Us
Gabapentincapsule400 mg/1oralWest ward Pharmaceutical Corp2007-07-092016-04-23Us
Gabapentincapsule300 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-242016-04-05Us
Gabapentincapsule300 mg/1oralMajor Pharmaceuticals2010-05-102016-04-05Us
Gabapentintablet800 mg/1oralREMEDYREPACK INC.2014-07-072016-04-05Us
Gabapentincapsule300 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-01-232016-04-23Us
Gabapentincapsule100 mg/1oralCardinal Health2011-01-292016-04-05Us
Gabapentinsolution250 mg/5mLoralKiel Laboratories, Inc.2012-05-012016-04-05Us
Gabapentincapsule300 mg/1oralCardinal Health2010-05-102016-04-05Us
Gabapentincapsule100 mg/1oralClinical Solutions Wholesale2009-11-242016-04-05Us
Gabapentincapsule300 mg/1oralCardinal Health2014-07-012016-04-05Us
Gabapentintablet, film coated100 mg/1oralApotex Corp.2006-10-102016-04-05Us
Gabapentintablet, film coated600 mg/1oralCardinal Health2004-02-142016-04-05Us
Gabapentincapsule100 mg/1oralGolden State Medical Supply, Inc.2010-05-172016-04-05Us
Gabapentincapsule400 mg/1oralDIRECT RX2015-01-012016-04-05Us
Gabapentincapsule400 mg/1oralREMEDYREPACK INC.2015-06-092016-04-05Us
Gabapentincapsule100 mg/1oralRanbaxy Pharmaceuticals Inc.2005-11-022016-04-05Us
Gabapentintablet800 mg/1oralProficient Rx LP2006-04-012016-04-05Us
Gabapentincapsule300 mg/1oralReady Meds2010-05-172016-04-05Us
Gabapentincapsule300 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2004-10-042016-04-05Us
Gabapentincapsule300 mg/1oralMed Vantx, Inc.2004-10-042016-04-05Us
Gabapentinsolution250 mg/5mLoralAmneal Pharmaceuticals of New York, LLC2011-09-302016-04-05Us
Gabapentintablet, film coated800 mg/1oralAmerican Health Packaging2012-08-312016-05-31Us
Gabapentincapsule400 mg/1oralAphena Pharma Solutions Tennessee, Llc2004-10-042016-04-05Us
Gabapentincapsule400 mg/1oralSTAT Rx USA LLC2009-11-242016-04-05Us
Gabapentincapsule100 mg/1oralPreferred Pharmaceuticals, Inc.2015-04-132016-04-05Us
Gabapentincapsule400 mg/1oralBlenheim Pharmacal, Inc.2010-05-172016-04-05Us
Gabapentincapsule300 mg/1oralKeltman Pharmaceuticals Inc.2009-12-152016-04-05Us
Gabapentintablet600 mg/1oralCamber Pharmaceuticals, Inc.2012-10-292016-04-05Us
Gabapentintablet, film coated600 mg/1oralExelan Pharmaceuticals Inc.2012-11-022016-04-05Us
Gabapentintablet, film coated800 mg/1oralRebel Distributors Corp.2006-08-242016-04-05Us
Gabapentincapsule400 mg/1oralMc Kesson Contract Packaging2011-12-092016-04-05Us
Gabapentincapsule100 mg/1oralRebel Distributors Corp2009-11-242016-04-05Us
Gabapentincapsule300 mg/1oralScie Gen Pharmaceuticals, Inc.2016-02-182016-04-05Us
Gabapentincapsule300 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2009-11-242016-04-05Us
Gabapentincapsule400 mg/1oralAphena Pharma Solutions Tennessee, Inc.2010-05-172016-04-05Us
Gabapentincapsule300 mg/1oralSTAT Rx USA LLC2009-11-242016-04-05Us
Gabapentincapsule100 mg/1oralActavis Pharma, Inc.2014-03-172016-04-05Us
Gabapentintablet, film coated600 mg/1oralSolco healthcare U.S., LLC2014-11-012016-04-05Us
Gabapentintablet800 mg/1oralREMEDYREPACK INC.2011-09-232016-04-05Us
Gabapentincapsule400 mg/1oralREMEDYREPACK INC.2011-03-312016-04-05Us
Gabapentintablet, film coated800 mg/1oralLake Erie Medical & Surgical S6758upply DBA Quality Care Products LLC2010-12-062016-04-05Us
Gabapentincapsule100 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-242016-04-05Us
Gabapentincapsule100 mg/1oralMajor Pharmaceuticals2010-05-102016-04-05Us
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2014-05-222016-04-05Us
Gabapentintablet, film coated800 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2004-10-212016-04-23Us
Gabapentincapsule100 mg/1oralCardinal Health2011-01-292016-04-05Us
Gabapentincapsule300 mg/1oralNew Horizon Rx Group, LLC2013-08-252016-04-05Us
Gabapentincapsule100 mg/1oralCardinal Health2010-05-102016-04-05Us
Gabapentincapsule100 mg/1oralClinical Solutions Wholesale, Llc2011-01-292016-04-05Us
Gabapentincapsule300 mg/1oralCardinal Health2009-11-242016-04-05Us
Gabapentincapsule400 mg/1oralApotex Corp.2005-04-062016-04-05Us
Gabapentincapsule100 mg/1oralCardinal Health2012-03-052016-04-05Us
Gabapentincapsule400 mg/1oralGolden State Medical Supply, Inc.2013-03-082016-04-05Us
Gabapentincapsule100 mg/1oralDIRECT RX2015-01-012016-04-05Us
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2015-04-162016-04-05Us
Gabapentincapsule100 mg/1oralProficient Rx LP2010-05-172016-04-05Us
Gabapentintablet, film coated600 mg/1oralProficient Rx2004-02-142016-04-05Us
Gabapentincapsule300 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2012-10-292016-04-05Us
Gabapentincapsule100 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2004-10-042016-04-05Us
Gabapentintablet, film coated800 mg/1oralAurobindo Pharma Limited2011-10-062016-04-05Us
Gabapentincapsule400 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-242016-04-05Us
Gabapentintablet, film coated600 mg/1oralAmerican Health Packaging2012-08-312016-06-30Us
Gabapentincapsule300 mg/1oralAphena Pharma Solutions Tennessee, Llc2004-10-042016-04-05Us
Gabapentintablet, film coated800 mg/1oralSTAT Rx USA LLC2006-08-242016-04-05Us
Gabapentintablet600 mg/1oralPreferred Pharmaceuticals, Inc.2015-04-152016-04-05Us
Gabapentintablet800 mg/1oralBlenheim Pharmacal, Inc.2006-04-012016-04-05Us
Gabapentincapsule400 mg/1oralKeltman Pharmaceuticals Inc.2009-12-152016-04-05Us
Gabapentincapsule400 mg/1oralCamber Pharmaceuticals Inc.2010-05-172016-04-05Us
Gabapentincapsule400 mg/1oralExelan Pharmaceuticals, Inc.2010-04-262016-04-05Us
Gabapentintablet, film coated600 mg/1oralRebel Distributors Corp.2006-08-242016-04-05Us
Gabapentincapsule300 mg/1oralMc Kesson Contract Packaging2011-08-292016-04-05Us
Gabapentintablet600 mg/1oralRebel Distributors Corp2011-02-092016-04-05Us
Gabapentincapsule100 mg/1oralScie Gen Pharmaceuticals, Inc.2016-02-182016-04-05Us
Gabapentincapsule600 mg/1oralRx Change Co.2014-11-092016-04-05Us
Gabapentincapsule300 mg/1oralAphena Pharma Solutions Tennessee, Inc.2010-05-172016-04-05Us
Gabapentincapsule100 mg/1oralSTAT Rx USA LLC2009-11-242016-04-05Us
Gabapentincapsule400 mg/1oralMedsource Pharmaceuticals2010-05-172016-04-05Us
Gabapentincapsule400 mg/1oralSolco healthcare U.S., LLC2012-10-152016-04-05Us
Gabapentintablet800 mg/1oralREMEDYREPACK INC.2011-07-282016-04-05Us
Gabapentintablet800 mg/1oralREMEDYREPACK INC.2011-05-252016-04-05Us
Gabapentintablet600 mg/1oralLake Erie Medica & Surgical Supply DBA Quality Care Products LLC2011-11-042016-04-05Us
Gabapentincapsule400 mg/1oralREMEDYREPACK INC.2013-02-152016-04-05Us
Gabapentincapsule400 mg/1oralBreckenridge Pharmaceutical, Inc.2012-10-152016-04-05Us
Gabapentintablet800 mg/1oralMylan Pharmaceuticals Inc.2012-08-312016-04-23Us
Gabapentintablet, film coated600 mg/1oralUnit Dose Services2006-08-242016-04-05Us
Gabapentincapsule300 mg/1oralWest ward Pharmaceutical Corp2007-07-092016-04-23Us
Gabapentincapsule400 mg/1oralCardinal Health2009-11-242016-04-05Us
Gabapentincapsule300 mg/1oralApotex Corp.2005-04-062016-04-05Us
Gabapentincapsule400 mg/1oralCardinal Health2012-03-052016-04-05Us
Gabapentincapsule300 mg/1oralGolden State Medical Supply, Inc.2013-03-082016-04-05Us
Gabapentintablet, film coated800 mg/1oralDIRECT RX2014-01-012016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2015-02-252016-04-05Us
Gabapentintablet800 mg/1oralProficient Rx LP2012-10-292016-04-05Us
Gabapentintablet, film coated800 mg/1oralSun Pharmaceutical Industries Limited2006-08-242016-04-05Us
Gabapentincapsule400 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-11-242016-04-05Us
Gabapentintablet, film coated800 mg/1oralbryant ranch prepack2006-08-242016-04-05Us
Gabapentintablet, film coated600 mg/1oralAurobindo Pharma Limited2011-10-062016-04-05Us
Gabapentincapsule300 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-242016-04-05Us
Gabapentintablet, film coated800 mg/1oralBlue Point Laboratories2013-07-242016-04-05Us
Gabapentintablet600 mg/1oralContract Pharmacy Services Pa2009-08-302016-04-05Us
Gabapentintablet, film coated600 mg/1oralSTAT Rx USA LLC2004-02-142016-04-05Us
Gabapentincapsule300 mg/1oralPreferred Pharmaceuticals, Inc.2010-05-172016-04-05Us
Gabapentincapsule400 mg/1oralBlenheim Pharmacal, Inc.2014-04-042016-04-05Us
Gabapentintablet, film coated800 mg/1oralZydus Pharmaceuticals (USA) Inc.2012-10-162016-04-05Us
Gabapentincapsule300 mg/1oralCamber Pharmaceuticals Inc.2010-05-172016-04-05Us
Gabapentincapsule300 mg/1oralExelan Pharmaceuticals, Inc.2010-04-262016-04-05Us
Gabapentincapsule300 mg/1oralRebel Distributors Corp.2006-08-292016-04-05Us
Gabapentincapsule100 mg/1oralMc Kesson Contract Packaging2011-08-292016-04-05Us
Gabapentincapsule300 mg/1oralRebel Distributors Corp2010-05-172016-04-05Us
Gabapentincapsule300 mg/1oralPd Rx Pharmaceuticals, Inc.2008-01-312016-04-05Us
Gabapentincapsule300 mg/1oralRx Change Co.2014-10-262016-04-05Us
Gabapentintablet, film coated800 mg/1oralPd Rx Pharmaceuticals, Inc.2012-10-162016-04-05Us
Gabapentincapsule300 mg/1oralWestwood Manufacturing2010-01-232016-04-05Us
Gabapentintablet600 mg/1oralMedsource Pharmaceuticals2006-04-012016-04-05Us
Gabapentincapsule300 mg/1oralSolco healthcare U.S., LLC2012-10-152016-04-05Us
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2011-07-252016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2011-03-012016-04-05Us
Gabapentincapsule100 mg/1oralLake Erie Medical DBA Quality Care Products LLC2011-11-052016-04-05Us
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2012-03-232016-04-05Us
Gabapentincapsule300 mg/1oralBreckenridge Pharmaceutical, Inc.2012-10-152016-04-05Us
Gabapentintablet600 mg/1oralMylan Pharmaceuticals Inc.2012-08-312016-04-23Us
Gabapentincapsule100 mg/1oralUnit Dose Services2010-05-172016-04-05Us
Gabapentincapsule100 mg/1oralWest ward Pharmaceutical Corp2007-07-092016-04-23Us
Gabapentintablet600 mg/1oralH.J. Harkins Company, Inc.2006-04-012016-04-05Us
Gabapentincapsule400 mg/1oralMajor Pharmaceuticals2005-04-062016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2014-03-042016-04-05Us
Gabapentintablet, film coated600 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2004-02-142016-04-23Us
Gabapentincapsule400 mg/1oralCardinal Health2004-12-102016-04-05Us
Gabapentincapsule400 mg/1oralClinical Solutions Wholesale, Llc2011-01-292016-04-05Us
Gabapentincapsule300 mg/1oralCardinal Health2005-04-062016-04-05Us
Gabapentintablet800 mg/1oralClinical Solutions Wholesale, Llc2008-08-012016-04-05Us
Gabapentintablet600 mg/1oralProficient Rx LP2012-10-292016-04-05Us
Gabapentintablet, film coated600 mg/1oralSun Pharmaceutical Industries Limited2006-08-242016-04-05Us
Gabapentincapsule300 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-11-242016-04-05Us
Gabapentintablet600 mg/1oralbryant ranch prepack2006-04-012016-04-05Us
Gabapentincapsule400 mg/1oralAurobindo Pharma Limited2008-01-312016-04-05Us
Gabapentincapsule100 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-242016-04-05Us
Gabapentintablet, film coated600 mg/1oralBlue Point Laboratories2013-07-242016-04-05Us
Gabapentincapsule300 mg/1oralContract Pharmacy Services Pa2010-04-122016-04-05Us
Gabapentincapsule300 mg/1oralSTAT Rx USA LLC2004-10-042016-04-05Us
Gabapentincapsule100 mg/1oralPreferred Pharmaceuticals, Inc.2010-05-172016-04-05Us
Gabapentintablet600 mg/1oralBlenheim Pharmacal, Inc.2014-02-072016-04-05Us
Gabapentintablet, film coated600 mg/1oralZydus Pharmaceuticals (USA) Inc.2012-10-162016-04-05Us
Gabapentincapsule100 mg/1oralCamber Pharmaceuticals Inc.2010-05-172016-04-05Us
Gabapentincapsule100 mg/1oralExelan Pharmaceuticals, Inc.2010-04-262016-04-05Us
Gabapentincapsule100 mg/1oralRebel Distributors Corp.2009-09-242016-04-05Us
Gabapentincapsule300 mg/300mgoralAlivio Medical Products, Llc2015-10-012016-04-05Us
Gabapentinsolution250 mg/5mLoralAcella Pharmaceuticals, LLC2012-10-012016-04-05Us
Gabapentincapsule100 mg/1oralPd Rx Pharmaceuticals, Inc.2008-01-312016-04-05Us
Gabapentintablet, film coated800 mg/1oralAidarex Pharmaceuticals LLC2011-10-062016-04-05Us
Gabapentincapsule100 mg/1oralPd Rx Pharmaceuticals, Inc.2009-11-242016-04-05Us
Gabapentincapsule300 mg/1oralMsm Repackaging2012-10-152016-04-05Us
Gabapentincapsule300 mg/1oralMedsource Pharmaceuticals2009-11-242016-04-05Us
Gabapentincapsule100 mg/1oralSolco healthcare U.S., LLC2012-10-152016-04-05Us
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2011-07-192016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2011-04-192016-04-05Us
Gabapentincapsule400 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2010-11-042016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2012-03-222016-04-05Us
Gabapentincapsule100 mg/1oralBreckenridge Pharmaceutical, Inc.2012-10-152016-04-05Us
Gabapentincapsule400 mg/1oralActavis Pharma, Inc.2004-10-042016-04-23Us
Gabapentinsolution250 mg/5mLoralHi Tech Pharmacal Co., Inc.2011-02-232016-04-05Us
Gabapentincapsule400 mg/1oralWest ward Pharmaceutical Corp2007-07-092016-04-23Us
Gabapentintablet800 mg/1oralH.J. Harkins Company, Inc.2006-04-012016-04-05Us
Gabapentincapsule300 mg/1oralMajor Pharmaceuticals2005-04-062016-04-05Us
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2014-03-042016-04-05Us
Gabapentincapsule300 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2003-09-122016-04-23Us
Gabapentintablet600 mg/1oralCardinal Health2007-08-022016-04-05Us
Gabapentincapsule100 mg/1oralClinical Solutions Wholesale, Llc2009-11-242016-04-05Us
Gabapentincapsule400 mg/1oralPhysicians Total Care, Inc.2008-11-072016-04-05Us
Gabapentintablet800 mg/1oralLake Erie Medical DBA Quality Care Products LLC2008-08-012016-04-05Us
Gabapentincapsule300 mg/1oralCardinal Health2005-04-062016-04-05Us
Gabapentincapsule100 mg/1oralApotex Corp.2005-04-062016-04-05Us
Gabapentintablet, film coated600 mg/1oralCardinal Health2012-08-312016-04-05Us
Gabapentincapsule100 mg/1oralGolden State Medical Supply, Inc.2013-03-082016-04-05Us
Gabapentintablet600 1/1oralDIRECT RX2014-01-012016-04-05Us
Gabapentintablet, film coated800 mg/1oralSt Marys Medical Park Pharmacy2010-12-032016-04-05Us
Gabapentincapsule300 mg/1oralAurobindo Pharma Limited2008-01-312016-04-05Us
Gabapentincapsule100 mg/1oralTYA Pharmaceuticals2010-01-232016-04-05Us
Gabapentincapsule400 mg/1oralAscend Laboratories, LLC2011-01-292016-04-05Us
Gabapentincapsule400 mg/1oralContract Pharmacy Services Pa2010-07-192016-04-05Us
Gabapentincapsule100 mg/1oralSTAT Rx USA LLC2004-10-042016-04-05Us
Gabapentintablet600 mg/1oralPreferred Pharmaceuticals, Inc.2006-04-012016-04-05Us
Gabapentincapsule300 mg/1oralBlenheim Pharmacal, Inc.2014-04-042016-04-05Us
Gabapentintablet, film coated800 mg/1oralAmerican Health Packaging2014-09-012016-04-05Us
Gabapentincapsule400 mg/1oralMARKSANS PHARMA LIMITED2011-02-282016-04-05Us
Gabapentintablet, film coated800 mg/1oralAllied Pharma Inc2013-06-022016-04-05Us
Gabapentincapsule400 mg/1oralNorth Star Rx Llc2008-01-312016-04-05Us
Gabapentincapsule300 mg/1oralAvera Mc Kennan Hospital2015-09-162016-04-05Us
Gabapentincapsule400 mg/1oralLake Erie Medical DBA Quality Care Products LLC2006-08-242016-04-05Us
Gabapentintablet800 mg/1oralScie Gen Pharmaceuticals, Inc.2015-11-242016-04-05Us
Gabapentintablet, film coated600 mg/1oralAidarex Pharmaceuticals LLC2011-10-062016-04-05Us
Gabapentincapsule300 mg/1oralPd Rx Pharmaceuticals, Inc.2009-11-242016-04-05Us
Gabapentincapsule400 mg/1oralAv Kare, Inc.2012-05-042016-04-05Us
Gabapentintablet800 mg/1oralDIRECT RX2016-03-162016-04-01Us
Gabapentincapsule300 mg/1oralPharmaceutica North America, Inc.2014-02-122016-04-05Us
Gabapentintablet, film coated600 mg/1oralAphena Pharma Solutions Tennessee, Llc2012-11-022016-04-05Us
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2011-07-112016-04-05Us
Gabapentincapsule400 mg/1oralSafecor Health, LLC2014-09-302016-04-05Us
Gabapentincapsule300 mg/1oralLake Erie Medical DBA Quality Care Products LLC2010-09-172016-04-05Us
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2012-03-162016-04-05Us
Gabapentinsolution250 mg/5mLoralTaro Pharmaceuticals U.S.A., Inc.2013-07-032016-04-05Us
Gabapentincapsule300 mg/1oralActavis Pharma, Inc.2004-10-042016-11-30Us
Gabapentintablet, film coated800 mg/1oralAv Pak2015-02-132016-04-05Us
Gabapentincapsule300 mg/1oralWest ward Pharmaceutical Corp2007-07-092016-04-23Us
Gabapentincapsule100 mg/1oralH.J. Harkins Company, Inc.2010-05-172016-04-05Us
Gabapentincapsule100 mg/1oralMajor Pharmaceuticals2005-04-062016-04-05Us
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2014-02-182016-04-05Us
Gabapentincapsule400 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2003-09-122016-04-23Us
Gabapentincapsule100 mg/1oralCardinal Health2004-12-102016-04-05Us
Gabapentincapsule300 mg/1oralClinical Solutions Wholesale2011-01-292016-04-05Us
Gabapentincapsule100 mg/1oralPhysicians Total Care, Inc.2009-09-242016-04-05Us
Gabapentintablet600 mg/1oralPd Rx Pharmaceuticals, Inc.2006-04-012016-04-05Us
Gabapentincapsule100 mg/1oralCardinal Health2005-04-062016-04-05Us
Gabapentintablet, film coated600 mg/1oralGolden State Medical Supply, Inc.2006-09-152016-04-05Us
Gabapentincapsule400 mg/1oralCardinal Health2010-01-232016-04-05Us
Gabapentintablet, film coated600 mg/1001oralHikma Pharmaceutical2011-07-212016-04-05Us
Gabapentincapsule300 mg/1oralDIRECT RX2015-01-012016-04-05Us
Gabapentincapsule400 mg/1oralSt Marys Medical Park Pharmacy2010-12-012016-04-05Us
Gabapentintablet, film coated800 mg/1oralProficient Rx LP2011-10-062016-04-05Us
Gabapentincapsule400 mg/1oralSun Pharmaceutical Industries Limited2006-08-242016-04-05Us
Gabapentincapsule100 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-11-242016-04-05Us
Gabapentincapsule300 mg/1oralbryant ranch prepack2010-05-172016-04-05Us
Gabapentincapsule400 mg/1oralActavis Pharma Manufacturing Pvt Ltd. (SOD)2010-01-232016-03-12Us
Gabapentintablet800 mg/1oralGlenmark Pharmaceuticals Inc., Usa2006-04-012016-04-05Us
Gabapentincapsule300 mg/1oralBlenheim Pharmacal, Inc.2010-01-042016-04-05Us
Gabapentintablet, film coated600 mg/1oralAmerican Health Packaging2014-11-032016-04-05Us
Gabapentincapsule300 mg/1oralMARKSANS PHARMA LIMITED2011-02-282016-04-05Us
Gabapentintablet, film coated600 mg/1oralAllied Pharma Inc2013-06-022016-04-05Us
Gabapentincapsule300 mg/1oralNorth Star Rx Llc2008-01-312016-04-05Us
Gabapentintablet, film coated600 mg/1oralPreferred Pharmaceuticals, Inc.2012-01-272016-04-05Us
Gabapentintablet600 mg/1oralLake Erie Medical DBA Quality Care Products LLC2008-07-112016-04-05Us
Gabapentintablet600 mg/1oralScie Gen Pharmaceuticals, Inc.2015-11-242016-04-05Us
Gabapentincapsule400 mg/1oralAidarex Pharmaceuticals LLC2009-11-242016-04-05Us
Gabapentintablet800 mg/1oralAscend Laboratories, LLC2015-11-012016-04-05Us
Gabapentintablet, film coated800 mg/1oralPd Rx Pharmaceuticals, Inc.2004-02-142016-04-05Us
Gabapentincapsule300 mg/1oralAv Kare, Inc.2012-05-042016-04-05Us
Gabapentincapsule400 mg/1oralCarilion Materials Management2004-10-042016-04-05Us
Gabapentincapsule400 mg/1oralAphena Pharma Solutions Tennessee, Llc2008-01-312016-04-05Us
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2011-07-082016-04-05Us
Gabapentincapsule100 mg/1oralSafecor Health, LLC2014-09-302016-04-05Us
Gabapentincapsule400 mg/1oralTIME CAP LABORATORIES, INC2015-12-302016-04-05Us
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2012-03-072016-04-05Us
Gabapentincapsule300 mg/1oralNorthwind Pharmaceuticals2014-12-232016-04-05Us
Gabapentincapsule100 mg/1oralActavis Pharma, Inc.2004-10-042016-11-30Us
Gabapentintablet, film coated600 mg/1oralAv Pak2015-02-132016-04-05Us
Gabapentincapsule100 mg/1oralWest ward Pharmaceutical Corp2007-07-092016-04-23Us
Gabapentincapsule400 mg/1oralLucid Pharma Llc2008-01-312016-04-05Us
Gabapentincapsule300 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-01-232016-04-23Us
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2014-01-302016-04-05Us
Gabapentincapsule100 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2003-09-122016-04-23Us
Gabapentincapsule300 mg/1oralCardinal Health2007-06-202016-04-05Us
Gabapentincapsule300 mg/1oralClinical Solutions Wholesale2011-01-292016-04-05Us
Gabapentintablet600 mg/1oralPhysicians Total Care, Inc.2005-02-142016-04-05Us
Gabapentincapsule100 mg/1oralPd Rx Pharmaceuticals, Inc.2004-10-042016-04-05Us
Gabapentincapsule400 mg/1oralCardinal Health2005-04-062016-04-05Us
Gabapentintablet, film coated600 mg/1oralGolden State Medical Supply, Inc.2006-09-152016-04-05Us
Gabapentincapsule300 mg/1oralCardinal Health2010-01-232016-04-05Us
Gabapentintablet, film coated800 mg/1oralHikma Pharmaceutical2011-07-212016-04-05Us
Gabapentincapsule100 mg/1oralDIRECT RX2015-01-012016-04-05Us
Gabapentintablet, film coated600 mg/1oralApotex Corp.2006-09-152016-03-29Us
Gabapentintablet600 mg/1oralProficient Rx LP2006-04-012016-04-05Us
Gabapentincapsule300 mg/1oralSun Pharmaceutical Industries Limited2006-08-242016-04-05Us
Gabapentintablet, film coated600 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2012-10-162016-04-05Us
Gabapentincapsule400 mg/1oralbryant ranch prepack2010-05-172016-04-05Us
Gabapentincapsule100 mg/1oralAurobindo Pharma Limited2008-01-312016-04-05Us
Gabapentincapsule300 mg/1oralTYA Pharmaceuticals2010-05-172016-04-05Us
Gabapentincapsule300 mg/1oralAscend Laboratories, LLC2011-01-292016-04-05Us
Gabapentincapsule100 mg/1oralDispensing Solutions, Inc.2007-07-092016-04-05Us
Gabapentincapsule400 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2010-05-172016-04-05Us
Gabapentincapsule300 mg/1oralLake Erie Medical DBA Quality Care Products LLC2009-11-242016-04-05Us
Gabapentincapsule300 mg/1oralAidarex Pharmaceuticals LLC2009-11-242016-04-05Us
Gabapentintablet600 mg/1oralAscend Laboratories, LLC2015-11-012016-04-05Us
Gabapentincapsule400 mg/1oralPd Rx Pharmaceuticals, Inc.2004-10-042016-04-05Us
Gabapentincapsule100 mg/1oralAv Kare, Inc.2012-05-042016-04-05Us
Gabapentincapsule300 mg/1oralDepartment Of State Health Services, Pharmacy Branch2010-01-232016-04-05Us
Gabapentincapsule300 mg/1oralPharmaceutica North America, Inc.2012-08-092016-04-05Us
Gabapentincapsule300 mg/1oralAphena Pharma Solutions Tennessee, Llc2008-01-312016-04-05Us
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2011-06-272016-04-05Us
Gabapentincapsule300 mg/1oralSafecor Health, LLC2014-09-302016-04-05Us
Gabapentincapsule300 mg/1oralTIME CAP LABORATORIES, INC2015-12-302016-04-05Us
Gabapentintablet800 mg/1oralREMEDYREPACK INC.2011-12-022016-04-05Us
Gabapentintablet800 mg/1oralUnit Dose Services2008-08-012016-04-05Us
Gabapentintablet, film coated800 mg/1oralActavis Pharma, Inc.2004-02-142016-04-23Us
Gabapentincapsule400 mg/1oralAv Pak2014-09-152016-04-05Us
Gabapentintablet800 mg/1oralTeva Pharmaceuticals USA Inc2008-08-012016-04-23Us
Gabapentincapsule300 mg/1oralLucid Pharma Llc2008-01-312016-04-05Us
Gabapentincapsule100 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-03-172016-04-23Us
Gabapentintablet, film coated800 mg/1oralREMEDYREPACK INC.2014-01-092016-04-05Us
Gabapentincapsule300 mg/1oralLiberty Pharmaceuticals, Inc.2009-11-242016-04-23Us
Gabapentincapsule400 mg/1oralCardinal Health2007-06-202016-04-05Us
Gabapentintablet, film coated600 mg/1oralClinical Solutions Wholesale2006-08-242016-04-05Us
Gabapentintablet800 mg/1oralPhysicians Total Care, Inc.2004-12-162016-04-05Us
Gabapentincapsule300 mg/1oralPd Rx Pharmaceuticals, Inc.2010-05-172016-04-05Us
Gabapentincapsule300 mg/1oralCardinal Health2011-04-012016-04-05Us
Gabapentincapsule400 mg/1oralGolden State Medical Supply, Inc.2010-05-172016-04-05Us
Gabapentincapsule100 mg/1oralCardinal Health2010-01-232016-04-05Us
Gabapentincapsule400 mg/1oralHikma Pharmaceutical2007-07-092016-04-05Us
Gabapentincapsule400 mg/1oralDIRECT RX2014-01-012016-04-05Us
Gabapentintablet, film coated600 mg/1oralApotex Corp.2006-09-152016-04-05Us
Gabapentincapsule400 mg/1oralProficient Rx LP2010-05-172016-04-05Us
Gabapentincapsule100 mg/1oralSun Pharmaceutical Industries Limited2006-08-242016-04-05Us
Gabapentintablet, film coated600 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2004-02-142016-04-05Us
Gabapentincapsule100 mg/1oralbryant ranch prepack2009-11-242016-04-05Us
Gabapentintablet, film coated800 mg/1oralCadila Healthcare Limited2012-10-162016-04-05Us
Gabapentincapsule100 mg/1oralTYA Pharmaceuticals2010-05-172016-04-05Us
Gabapentincapsule100 mg/1oralAscend Laboratories, LLC2011-01-292016-04-05Us
Gabapentincapsule300 mg/1oralDispensing Solutions, Inc.2007-07-092016-04-05Us
Gabapentincapsule300 mg/1oralActavis Pharma Manufacturing Pvt Ltd. (SOD)2010-01-232016-03-12Us
Gabapentintablet600 mg/1oralGlenmark Pharmaceuticals Inc., Usa2006-04-012016-04-05Us
Gabapentincapsule100 mg/1oralBlenheim Pharmacal, Inc.2010-10-082016-04-05Us
Gabapentincapsule100 mg/1oralAmerican Health Packaging2014-07-012016-04-05Us
Gabapentincapsule100 mg/1oralMARKSANS PHARMA LIMITED2011-02-282016-04-05Us
Gabapentincapsule100 mg/1oralMc Kesson Contract Packaging2014-03-172016-04-05Us
Gabapentincapsule100 mg/1oralNorth Star Rx Llc2008-01-312016-04-05Us
Gabapentintablet800 mg/1oralPreferred Pharmaceuticals Inc.2015-08-202016-04-05Us
Gabapentin KitkitPharmaceutica North America, Inc.2012-08-282016-04-05Us
Over the Counter ProductsNot Available
International Brands
NameCompany
AcloniumNot Available
Novo-GabapentinNot Available
Brand mixtures
NameLabellerIngredients
Dipentocaine Topical Cream Compounding KitAlvix Laboratories, LLC
Therapentin-60Physician Therapeutics Llc
Therapentin-90Physician Therapeutics Llc
SaltsNot Available
Categories
UNII6CW7F3G59X
CAS number60142-96-3
WeightAverage: 171.2368
Monoisotopic: 171.125928793
Chemical FormulaC9H17NO2
InChI KeyInChIKey=UGJMXCAKCUNAIE-UHFFFAOYSA-N
InChI
InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)
IUPAC Name
2-[1-(aminomethyl)cyclohexyl]acetic acid
SMILES
NCC1(CC(O)=O)CCCCC1
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as gamma amino acids and derivatives. These are amino acids having a (-NH2) group attached to the gamma carbon atom.
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
Sub ClassAmino acids, peptides, and analogues
Direct ParentGamma amino acids and derivatives
Alternative Parents
Substituents
  • Gamma amino acid or derivatives
  • Amino fatty acid
  • Fatty acyl
  • Monocarboxylic acid or derivatives
  • Carboxylic acid
  • Hydrocarbon derivative
  • Primary amine
  • Organooxygen compound
  • Organonitrogen compound
  • Primary aliphatic amine
  • Carbonyl group
  • Amine
  • Aliphatic homomonocyclic compound
Molecular FrameworkAliphatic homomonocyclic compounds
External Descriptors
Pharmacology
IndicationFor the management of postherpetic neuralgia in adults and as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in patients over 12 years of age with epilepsy.
PharmacodynamicsGabapentin, an analog of GABA, is used as an anticonvulsant to treat partial seizures, amyotrophic lateral sclerosis (ALS), and painful neuropathies. Potential uses include monotherapy of refractory partial seizure disorders, and treatment of spasticity in multiple sclerosis, tremor. mood disorders, and attenuation of disruptive behaviors in dementia. Gabapentin has high lipid solubility, is not metabolized by the liver, has no protein binding, and doesn't possess the usual drug interactions.
Mechanism of actionGabapentin interacts with cortical neurons at auxillary subunits of voltage-sensitive calcium channels. Gabapentin increases the synaptic concentration of GABA, enhances GABA responses at non-synaptic sites in neuronal tissues, and reduces the release of mono-amine neurotransmitters. One of the mechanisms implicated in this effect of gabapentin is the reduction of the axon excitability measured as an amplitude change of the presynaptic fibre volley (FV) in the CA1 area of the hippocampus. This is mediated through its binding to presynaptic NMDA receptors. Other studies have shown that the antihyperalgesic and antiallodynic effects of gabapentin are mediated by the descending noradrenergic system, resulting in the activation of spinal alpha2-adrenergic receptors. Gabapentin has also been shown to bind and activate the adenosine A1 receptor.
Related Articles
AbsorptionRapid. Absorbed in part by the L-amino acid transport system, which is a carrier-mediated, saturable transport system; as the dose increases, bioavailability decreases. Bioavailability ranges from approximately 60% for a 900 mg dose per day to approximately 27% for a 4800 milligram dose per day. Food has a slight effect on the rate and extent of absorption of gabapentin (14% increase in AUC).
Volume of distribution
  • 58±6 L
Protein bindingLess than 3% of gabapentin circulates bound to plasma protein.
Metabolism

All pharmacological actions following gabapentin administration are due to the activity of the parent compound; gabapentin is not appreciably metabolized in humans.

Route of eliminationGabapentin is eliminated from the systemic circulation by renal excretion as unchanged drug. Gabapentin is not appreciably metabolized in humans.
Half life5-7 hours
Clearance
  • 190 mL/min
ToxicitySymptoms of overdose include ataxia, labored breathing, ptosis, sedation, hypoactivity, and excitation.
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.941
Blood Brain Barrier+0.9382
Caco-2 permeable-0.7271
P-glycoprotein substrateNon-substrate0.6557
P-glycoprotein inhibitor INon-inhibitor0.9789
P-glycoprotein inhibitor IINon-inhibitor0.8866
Renal organic cation transporterNon-inhibitor0.7982
CYP450 2C9 substrateNon-substrate0.893
CYP450 2D6 substrateNon-substrate0.8124
CYP450 3A4 substrateNon-substrate0.7612
CYP450 1A2 substrateNon-inhibitor0.9409
CYP450 2C9 inhibitorNon-inhibitor0.9273
CYP450 2D6 inhibitorNon-inhibitor0.9418
CYP450 2C19 inhibitorNon-inhibitor0.9547
CYP450 3A4 inhibitorNon-inhibitor0.8438
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9706
Ames testNon AMES toxic0.9162
CarcinogenicityNon-carcinogens0.8536
BiodegradationNot ready biodegradable0.7046
Rat acute toxicity1.6472 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9406
hERG inhibition (predictor II)Non-inhibitor0.8659
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Actavis elizabeth llc
  • Amneal pharmaceuticals ny llc
  • Apotex inc etobicoke site
  • Aurobindo pharma usa inc
  • Hikma pharmaceuticals
  • Invagen pharmaceuticals inc
  • Ivax pharmaceuticals inc sub teva pharmaceuticals usa
  • Mutual pharmaceutical co inc
  • Ranbaxy laboratories ltd
  • Sandoz inc
  • Sun pharmaceutical industries ltd
  • Teva pharmaceuticals usa
  • Watson laboratories inc
  • Pfizer pharmaceuticals ltd
  • Parke davis div warner lambert co
  • Glenmark generics ltd
  • Matrix laboratories ltd
  • Teva pharmaceuticals usa inc
Packagers
Dosage forms
FormRouteStrength
Kittopical
Kitoral
Capsuleoral300 mg/300mg
Capsuleoral600 mg/1
Suspensionoral250 mg/5mL
Tabletoral600 1/1
Tabletoral600 mg/1
Tabletoral800 mg/1
Tablet, film coatedoral100 mg/1
Tablet, film coatedoral400 mg/1
Tablet, film coatedoral600 mg/1001
Tablet (immediate release)oral600 mg
Tablet (immediate release)oral800 mg
Tablet, film coatedoral300 mg/1
Kit
Capsuleoral100 mg/1
Capsuleoral300 mg/1
Capsuleoral400 mg/1
Solutionoral250 mg/5mL
Tablet, film coatedoral600 mg/1
Tablet, film coatedoral800 mg/1
Tabletoral600 mg
Tabletoral800 mg
Capsuleoral100 mg
Capsuleoral300 mg
Capsuleoral400 mg
Kit
Prices
Unit descriptionCostUnit
Gabapentin powder30.0USD g
Neurontin 800 mg tablet4.73USD tablet
Neurontin 600 mg tablet3.94USD tablet
Gabapentin 800 mg tablet3.09USD tablet
Gabapentin 600 mg tablet2.58USD tablet
Neurontin 400 mg Capsule1.97USD capsule
Neurontin 300 mg Capsule1.67USD capsule
Gabapentin 400 mg tablet1.59USD tablet
Gabapentin 300 mg tablet1.32USD tablet
Gabapentin 400 mg Capsule1.21USD capsule
Gabapentin 300 mg Capsule1.02USD capsule
Apo-Gabapentin 400 mg Capsule0.76USD capsule
Co Gabapentin 400 mg Capsule0.76USD capsule
Mylan-Gabapentin 400 mg Capsule0.76USD capsule
Novo-Gabapentin 400 mg Capsule0.76USD capsule
Phl-Gabapentin 400 mg Capsule0.76USD capsule
Pms-Gabapentin 400 mg Capsule0.76USD capsule
Ran-Gabapentin 400 mg Capsule0.76USD capsule
Ratio-Gabapentin 400 mg Capsule0.76USD capsule
Neurontin 100 mg Capsule0.65USD capsule
Apo-Gabapentin 300 mg Capsule0.64USD capsule
Co Gabapentin 300 mg Capsule0.64USD capsule
Mylan-Gabapentin 300 mg Capsule0.64USD capsule
Novo-Gabapentin 300 mg Capsule0.64USD capsule
Phl-Gabapentin 300 mg Capsule0.64USD capsule
Pms-Gabapentin 300 mg Capsule0.64USD capsule
Ran-Gabapentin 300 mg Capsule0.64USD capsule
Ratio-Gabapentin 300 mg Capsule0.64USD capsule
Gabapentin 100 mg tablet0.53USD tablet
Gabapentin 100 mg Capsule0.41USD capsule
Neurontin 250 mg/5ml Solution0.32USD ml
Apo-Gabapentin 100 mg Capsule0.26USD capsule
Co Gabapentin 100 mg Capsule0.26USD capsule
Mylan-Gabapentin 100 mg Capsule0.26USD capsule
Novo-Gabapentin 100 mg Capsule0.26USD capsule
Phl-Gabapentin 100 mg Capsule0.26USD capsule
Pms-Gabapentin 100 mg Capsule0.26USD capsule
Ran-Gabapentin 100 mg Capsule0.26USD capsule
Ratio-Gabapentin 100 mg Capsule0.26USD capsule
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
CA2215923 No2001-10-092016-04-26Canada
CA2327285 No2005-06-142019-05-10Canada
US6054482 Yes1997-10-252017-10-25Us
US6340475 No1996-09-192016-09-19Us
US6488962 No2000-06-202020-06-20Us
US6635280 No1996-09-192016-09-19Us
US6723340 No2001-10-252021-10-25Us
US7256216 Yes2002-11-282022-11-28Us
US7438927 No2004-02-262024-02-26Us
US7731989 No2002-10-252022-10-25Us
US8192756 No2002-10-252022-10-25Us
US8252332 No2002-10-252022-10-25Us
US8333992 No2002-10-252022-10-25Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point162-166 °CNot Available
water solubility4490 mg/LNot Available
logP-1.10SANGSTER (1994)
Predicted Properties
PropertyValueSource
Water Solubility4.34 mg/mLALOGPS
logP-1.9ALOGPS
logP-1.3ChemAxon
logS-1.6ALOGPS
pKa (Strongest Acidic)4.63ChemAxon
pKa (Strongest Basic)9.91ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area63.32 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity46.33 m3·mol-1ChemAxon
Polarizability18.92 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
Spectra
Spectrum TypeDescriptionSplash Key
1D NMR1H NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
References
Synthesis Reference

Donald E. Butler, Barbara J. Greenman, “Gabapentin mohohydrate and a process for producing the same.” U.S. Patent US4960931, issued May, 1978.

US4960931
General References
  1. Mathew NT, Rapoport A, Saper J, Magnus L, Klapper J, Ramadan N, Stacey B, Tepper S: Efficacy of gabapentin in migraine prophylaxis. Headache. 2001 Feb;41(2):119-28. [PubMed:11251695 ]
  2. Backonja MM, Serra J: Pharmacologic management part 1: better-studied neuropathic pain diseases. Pain Med. 2004 Mar;5 Suppl 1:S28-47. [PubMed:14996228 ]
  3. Choudhuri I, Sarvananthan N, Gottlob I: Survey of management of acquired nystagmus in the United Kingdom. Eye (Lond). 2007 Sep;21(9):1194-7. Epub 2006 May 26. [PubMed:16732211 ]
  4. Pande AC, Crockatt JG, Janney CA, Werth JL, Tsaroucha G: Gabapentin in bipolar disorder: a placebo-controlled trial of adjunctive therapy. Gabapentin Bipolar Disorder Study Group. Bipolar Disord. 2000 Sep;2(3 Pt 2):249-55. [PubMed:11249802 ]
  5. Su TZ, Feng MR, Weber ML: Mediation of highly concentrative uptake of pregabalin by L-type amino acid transport in Chinese hamster ovary and Caco-2 cells. J Pharmacol Exp Ther. 2005 Jun;313(3):1406-15. Epub 2005 Mar 15. [PubMed:15769862 ]
External Links
ATC CodesN03AX12
AHFS Codes
  • 28:12.92
PDB EntriesNot Available
FDA labelDownload (1.5 MB)
MSDSDownload (73.3 KB)
Interactions
Drug Interactions
Drug
AcetaminophenThe metabolism of Gabapentin can be increased when combined with Acetaminophen.
Aluminum hydroxideThe serum concentration of Gabapentin can be decreased when it is combined with Aluminum hydroxide.
AmobarbitalThe metabolism of Gabapentin can be increased when combined with Amobarbital.
Atracurium besylateGabapentin may increase the neuromuscular blocking activities of Atracurium besylate.
AzelastineGabapentin may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
BaclofenThe risk or severity of adverse effects can be increased when Baclofen is combined with Gabapentin.
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
BuprenorphineGabapentin may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
ButabarbitalThe metabolism of Gabapentin can be increased when combined with Butabarbital.
ButalbitalThe metabolism of Gabapentin can be increased when combined with Butalbital.
CaffeineThe metabolism of Gabapentin can be increased when combined with Caffeine.
Calcium AcetateThe therapeutic efficacy of Gabapentin can be decreased when used in combination with Calcium Acetate.
Calcium carbonateThe therapeutic efficacy of Gabapentin can be decreased when used in combination with Calcium carbonate.
Calcium ChlorideThe therapeutic efficacy of Gabapentin can be decreased when used in combination with Calcium Chloride.
Calcium citrateThe therapeutic efficacy of Gabapentin can be decreased when used in combination with Calcium citrate.
Calcium gluconateThe therapeutic efficacy of Gabapentin can be decreased when used in combination with Calcium gluconate.
CimetidineThe serum concentration of Gabapentin can be increased when it is combined with Cimetidine.
Cisatracurium besylateGabapentin may increase the neuromuscular blocking activities of Cisatracurium besylate.
ClarithromycinThe metabolism of Gabapentin can be decreased when combined with Clarithromycin.
ClopidogrelThe therapeutic efficacy of Clopidogrel can be decreased when used in combination with Gabapentin.
DoxazosinDoxazosin may increase the hypotensive activities of Gabapentin.
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
DroperidolDroperidol may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
EfavirenzThe serum concentration of Gabapentin can be decreased when it is combined with Efavirenz.
ErythromycinThe metabolism of Gabapentin can be decreased when combined with Erythromycin.
EthanolGabapentin may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
FluconazoleThe serum concentration of Gabapentin can be increased when it is combined with Fluconazole.
FosphenytoinThe serum concentration of Fosphenytoin can be increased when it is combined with Gabapentin.
HydrocodoneGabapentin may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
HydroxyzineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
ItraconazoleThe risk or severity of adverse effects can be increased when Itraconazole is combined with Gabapentin.
KetoconazoleThe risk or severity of adverse effects can be increased when Ketoconazole is combined with Gabapentin.
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Gabapentin.
Magnesium chlorideMagnesium chloride may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
Magnesium citrateMagnesium citrate may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
Magnesium hydroxideThe serum concentration of Gabapentin can be decreased when it is combined with Magnesium hydroxide.
Magnesium oxideMagnesium oxide may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
Magnesium salicylateMagnesium salicylate may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
Magnesium SulfateMagnesium Sulfate may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
MefloquineThe therapeutic efficacy of Gabapentin can be decreased when used in combination with Mefloquine.
MethohexitalThe metabolism of Gabapentin can be increased when combined with Methohexital.
MethotrimeprazineGabapentin may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
MetyrosineGabapentin may increase the sedative activities of Metyrosine.
MianserinThe therapeutic efficacy of Gabapentin can be decreased when used in combination with Mianserin.
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
MirtazapineGabapentin may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
NafcillinThe metabolism of Gabapentin can be increased when combined with Nafcillin.
NitroprussideGabapentin may increase the hypotensive activities of Nitroprusside.
OrlistatThe serum concentration of Gabapentin can be decreased when it is combined with Orlistat.
OrphenadrineGabapentin may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
PancuroniumGabapentin may increase the neuromuscular blocking activities of Pancuronium.
ParaldehydeGabapentin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ParoxetineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Paroxetine.
PentobarbitalThe metabolism of Gabapentin can be increased when combined with Pentobarbital.
PerampanelPerampanel may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
PhenobarbitalThe metabolism of Gabapentin can be increased when combined with Phenobarbital.
PhenoxybenzaminePhenoxybenzamine may increase the hypotensive activities of Gabapentin.
PhentolaminePhentolamine may increase the hypotensive activities of Gabapentin.
PhenytoinThe serum concentration of Phenytoin can be increased when it is combined with Gabapentin.
PosaconazoleThe risk or severity of adverse effects can be increased when Posaconazole is combined with Gabapentin.
PramipexoleGabapentin may increase the sedative activities of Pramipexole.
PrazosinPrazosin may increase the hypotensive activities of Gabapentin.
RifabutinThe serum concentration of Gabapentin can be decreased when it is combined with Rifabutin.
RifampicinThe serum concentration of Gabapentin can be decreased when it is combined with Rifampicin.
RifapentineThe serum concentration of Gabapentin can be decreased when it is combined with Rifapentine.
RocuroniumGabapentin may increase the neuromuscular blocking activities of Rocuronium.
RopiniroleGabapentin may increase the sedative activities of Ropinirole.
RotigotineGabapentin may increase the sedative activities of Rotigotine.
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Gabapentin.
SecobarbitalThe metabolism of Gabapentin can be increased when combined with Secobarbital.
SilodosinSilodosin may increase the hypotensive activities of Gabapentin.
Sodium bicarbonateThe serum concentration of Gabapentin can be decreased when it is combined with Sodium bicarbonate.
Sodium oxybateSodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
SulfisoxazoleThe metabolism of Gabapentin can be decreased when combined with Sulfisoxazole.
SuvorexantGabapentin may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
TamsulosinTamsulosin may increase the hypotensive activities of Gabapentin.
TapentadolTapentadol may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
TelithromycinThe metabolism of Gabapentin can be decreased when combined with Telithromycin.
TerazosinTerazosin may increase the hypotensive activities of Gabapentin.
ThalidomideGabapentin may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
VecuroniumGabapentin may increase the neuromuscular blocking activities of Vecuronium.
VoriconazoleThe risk or severity of adverse effects can be increased when Voriconazole is combined with Gabapentin.
ZolpidemGabapentin may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Food Interactions
  • Avoid alcohol.
  • Take without regard to meals.

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Voltage-gated calcium channel activity
Specific Function:
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling (By similarity).
Gene Name:
CACNA2D1
Uniprot ID:
P54289
Molecular Weight:
124566.93 Da
References
  1. Maneuf YP, Luo ZD, Lee K: alpha2delta and the mechanism of action of gabapentin in the treatment of pain. Semin Cell Dev Biol. 2006 Oct;17(5):565-70. Epub 2006 Sep 24. [PubMed:17067834 ]
  2. Hota D, Bansal V, Pattanaik S: Evaluation of ketamine, nimodipine, gabapentin and imipramine in partial sciatic nerve transection model of neuropathic pain in rat: an experimental study. Methods Find Exp Clin Pharmacol. 2007 Sep;29(7):443-6. [PubMed:17982508 ]
  3. Gazulla J, Tintore MA: The P/Q-type voltage-dependent calcium channel as pharmacological target in spinocerebellar ataxia type 6: gabapentin and pregabalin may be of therapeutic benefit. Med Hypotheses. 2007;68(1):131-6. Epub 2006 Aug 8. [PubMed:16899342 ]
  4. Hendrich J, Van Minh AT, Heblich F, Nieto-Rostro M, Watschinger K, Striessnig J, Wratten J, Davies A, Dolphin AC: Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3628-33. doi: 10.1073/pnas.0708930105. Epub 2008 Feb 25. [PubMed:18299583 ]
  5. Hoffmann U, Dilekoz E, Kudo C, Ayata C: Gabapentin suppresses cortical spreading depression susceptibility. J Cereb Blood Flow Metab. 2010 Sep;30(9):1588-92. doi: 10.1038/jcbfm.2010.92. Epub 2010 Jun 30. [PubMed:20588320 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Voltage-gated calcium channel activity
Specific Function:
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) and possibly T-type (CACNA1G). Overexpression induces apoptosis.
Gene Name:
CACNA2D2
Uniprot ID:
Q9NY47
Molecular Weight:
129816.095 Da
References
  1. Hota D, Bansal V, Pattanaik S: Evaluation of ketamine, nimodipine, gabapentin and imipramine in partial sciatic nerve transection model of neuropathic pain in rat: an experimental study. Methods Find Exp Clin Pharmacol. 2007 Sep;29(7):443-6. [PubMed:17982508 ]
  2. Gazulla J, Tintore MA: The P/Q-type voltage-dependent calcium channel as pharmacological target in spinocerebellar ataxia type 6: gabapentin and pregabalin may be of therapeutic benefit. Med Hypotheses. 2007;68(1):131-6. Epub 2006 Aug 8. [PubMed:16899342 ]
  3. Hendrich J, Van Minh AT, Heblich F, Nieto-Rostro M, Watschinger K, Striessnig J, Wratten J, Davies A, Dolphin AC: Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3628-33. doi: 10.1073/pnas.0708930105. Epub 2008 Feb 25. [PubMed:18299583 ]
  4. Hoffmann U, Dilekoz E, Kudo C, Ayata C: Gabapentin suppresses cortical spreading depression susceptibility. J Cereb Blood Flow Metab. 2010 Sep;30(9):1588-92. doi: 10.1038/jcbfm.2010.92. Epub 2010 Jun 30. [PubMed:20588320 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Voltage-gated calcium channel activity
Specific Function:
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-...
Gene Name:
CACNA1B
Uniprot ID:
Q00975
Molecular Weight:
262493.84 Da
References
  1. Cheng JK, Chen CC, Yang JR, Chiou LC: The antiallodynic action target of intrathecal gabapentin: Ca2+ channels, KATP channels or N-methyl-d-aspartic acid receptors? Anesth Analg. 2006 Jan;102(1):182-7. [PubMed:16368827 ]
  2. Hendrich J, Van Minh AT, Heblich F, Nieto-Rostro M, Watschinger K, Striessnig J, Wratten J, Davies A, Dolphin AC: Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3628-33. doi: 10.1073/pnas.0708930105. Epub 2008 Feb 25. [PubMed:18299583 ]
  3. Hoffmann U, Dilekoz E, Kudo C, Ayata C: Gabapentin suppresses cortical spreading depression susceptibility. J Cereb Blood Flow Metab. 2010 Sep;30(9):1588-92. doi: 10.1038/jcbfm.2010.92. Epub 2010 Jun 30. [PubMed:20588320 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Purine nucleoside binding
Specific Function:
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
Gene Name:
ADORA1
Uniprot ID:
P30542
Molecular Weight:
36511.325 Da
References
  1. De Vry J, Kuhl E, Franken-Kunkel P, Eckel G: Pharmacological characterization of the chronic constriction injury model of neuropathic pain. Eur J Pharmacol. 2004 May 3;491(2-3):137-48. [PubMed:15140630 ]
  2. Zuchora B, Wielosz M, Urbanska EM: Adenosine A1 receptors and the anticonvulsant potential of drugs effective in the model of 3-nitropropionic acid-induced seizures in mice. Eur Neuropsychopharmacol. 2005 Jan;15(1):85-93. [PubMed:15572277 ]
  3. Kralic JE, Criswell HE, Osterman JL, O'Buckley TK, Wilkie ME, Matthews DB, Hamre K, Breese GR, Homanics GE, Morrow AL: Genetic essential tremor in gamma-aminobutyric acidA receptor alpha1 subunit knockout mice. J Clin Invest. 2005 Mar;115(3):774-9. [PubMed:15765150 ]
Kind
Protein group
Organism
Human
Pharmacological action
unknown
General Function:
Voltage-gated cation channel activity
Specific Function:
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
Components:
NameUniProt IDDetails
Glutamate receptor ionotropic, NMDA 1Q05586 Details
Glutamate receptor ionotropic, NMDA 2AQ12879 Details
Glutamate receptor ionotropic, NMDA 2BQ13224 Details
Glutamate receptor ionotropic, NMDA 2CQ14957 Details
Glutamate receptor ionotropic, NMDA 2DO15399 Details
Glutamate receptor ionotropic, NMDA 3AQ8TCU5 Details
Glutamate receptor ionotropic, NMDA 3BO60391 Details
References
  1. Shimoyama M, Shimoyama N, Hori Y: Gabapentin affects glutamatergic excitatory neurotransmission in the rat dorsal horn. Pain. 2000 Apr;85(3):405-14. [PubMed:10781913 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
L-valine transaminase activity
Specific Function:
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
Gene Name:
BCAT1
Uniprot ID:
P54687
Molecular Weight:
42965.815 Da
References
  1. Goto M, Miyahara I, Hirotsu K, Conway M, Yennawar N, Islam MM, Hutson SM: Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. J Biol Chem. 2005 Nov 4;280(44):37246-56. Epub 2005 Sep 1. [PubMed:16141215 ]
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Drug created on June 13, 2005 07:24 / Updated on May 06, 2016 03:14