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Identification
NameGabapentin
Accession NumberDB00996  (APRD00015)
TypeSmall Molecule
GroupsApproved, Investigational
DescriptionGabapentin (brand name Neurontin) is a medication originally developed for the treatment of epilepsy. Presently, gabapentin is widely used to relieve pain, especially neuropathic pain. Gabapentin is well tolerated in most patients, has a relatively mild side-effect profile, and passes through the body unmetabolized.
Structure
Thumb
Synonyms
1-(Aminomethyl)cyclohexaneacetic acid
Gabapentin GR
Gabapentina
Gabapentine
Gabapentino
Gabapentinum
Gabapetin
Neurontin
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Act Gabapentincapsule100 mgoralActavis Pharma Company2005-02-16Not applicableCanada
Act Gabapentincapsule300 mgoralActavis Pharma Company2005-02-16Not applicableCanada
Act Gabapentincapsule400 mgoralActavis Pharma Company2005-02-16Not applicableCanada
Auro-gabapentincapsule100 mgoralAuro Pharma Inc2011-06-15Not applicableCanada
Auro-gabapentincapsule300 mgoralAuro Pharma Inc2011-06-15Not applicableCanada
Auro-gabapentincapsule400 mgoralAuro Pharma Inc2011-06-15Not applicableCanada
Auro-gabapentin Tabletstablet800 mgoralAuro Pharma IncNot applicableNot applicableCanada
Auro-gabapentin Tabletstablet600 mgoralAuro Pharma IncNot applicableNot applicableCanada
Bci Gabapentincapsule300 mgoralBaker Cummins IncNot applicableNot applicableCanada
Bio-gabapentintablet600 mgoralBiomed PharmaNot applicableNot applicableCanada
Bio-gabapentintablet800 mgoralBiomed PharmaNot applicableNot applicableCanada
Dom-gabapentincapsule400 mgoralDominion Pharmacal2002-03-11Not applicableCanada
Dom-gabapentintablet600 mgoralDominion PharmacalNot applicableNot applicableCanada
Dom-gabapentintablet800 mgoralDominion PharmacalNot applicableNot applicableCanada
Dom-gabapentincapsule100 mgoralDominion Pharmacal2002-03-11Not applicableCanada
Dom-gabapentincapsule300 mgoralDominion Pharmacal2002-03-11Not applicableCanada
Gabapentincapsule100 mgoralSanis Health Inc2010-07-30Not applicableCanada
Gabapentincapsule100 mgoralSorres Pharma Inc2009-02-262014-06-20Canada
Gabapentincapsule100 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Gabapentincapsule100 mgoralApotex IncNot applicableNot applicableCanada
Gabapentinsuspension250 mg/5mLoralGreenstone LLC2011-03-29Not applicableUs
Gabapentincapsule100 mgoralSivem Pharmaceuticals Ulc2003-01-07Not applicableCanada
Gabapentincapsule300 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Gabapentincapsule300 mgoralSanis Health Inc2010-07-30Not applicableCanada
Gabapentincapsule300 mgoralSorres Pharma Inc2009-02-262014-06-20Canada
Gabapentincapsule100 mg/1oralGreenstone LLC1993-12-30Not applicableUs
Gabapentincapsule400 mgoralApotex IncNot applicableNot applicableCanada
Gabapentincapsule100 mgoralOmni Laboratories Division, Warner Lambert Canada Inc.Not applicableNot applicableCanada
Gabapentintablet800 mgoralApotex IncNot applicableNot applicableCanada
Gabapentincapsule300 mgoralSivem Pharmaceuticals Ulc2003-01-07Not applicableCanada
Gabapentintablet600 mgoralSanis Health Inc2014-09-23Not applicableCanada
Gabapentincapsule400 mgoralSorres Pharma Inc2009-02-262014-06-20Canada
Gabapentincapsule400 mgoralCobalt Pharmaceuticals CompanyNot applicableNot applicableCanada
Gabapentincapsule400 mgoralSanis Health Inc2010-07-30Not applicableCanada
Gabapentincapsule300 mg/1oralGreenstone LLC1993-12-30Not applicableUs
Gabapentincapsule300 mgoralOmni Laboratories Division, Warner Lambert Canada Inc.Not applicableNot applicableCanada
Gabapentintablet600 mgoralSivem Pharmaceuticals Ulc2012-06-26Not applicableCanada
Gabapentintablet600 mgoralApotex IncNot applicableNot applicableCanada
Gabapentintablet, film coated600 mg/1oralGreenstone LLC1998-10-09Not applicableUs
Gabapentincapsule400 mgoralSivem Pharmaceuticals Ulc2003-01-07Not applicableCanada
Gabapentincapsule300 mgoralGenpharm Ulc2006-01-172009-02-17Canada
Gabapentintablet800 mgoralSanis Health Inc2014-09-23Not applicableCanada
Gabapentincapsule400 mg/1oralGreenstone LLC1993-12-30Not applicableUs
Gabapentincapsule400 mgoralOmni Laboratories Division, Warner Lambert Canada Inc.Not applicableNot applicableCanada
Gabapentintablet, film coated800 mg/1oralGreenstone LLC1998-10-09Not applicableUs
Gabapentintablet800 mgoralSivem Pharmaceuticals Ulc2012-06-26Not applicableCanada
Gabapentincapsule300 mgoralApotex IncNot applicableNot applicableCanada
Gabapentin Capsulescapsule100 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Gabapentin Capsulescapsule300 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Gabapentin Capsulescapsule400 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada
Gabapentin Capsules USPcapsule400 mgoralAccord Healthcare Inc2014-06-04Not applicableCanada
Gabapentin Capsules USPcapsule100 mgoralAccord Healthcare Inc2014-06-04Not applicableCanada
Gabapentin Capsules USPcapsule300 mgoralAccord Healthcare Inc2014-06-04Not applicableCanada
Gabapentin Tablets USPtablet800 mgoralAccord Healthcare Inc2012-10-12Not applicableCanada
Gabapentin Tablets USPtablet (immediate release)600 mgoralGlenmark Pharmaceuticals Canada Inc.2016-04-04Not applicableCanada
Gabapentin Tablets USPtablet (immediate release)800 mgoralGlenmark Pharmaceuticals Canada Inc.2016-04-04Not applicableCanada
Gabapentin Tablets USPtablet600 mgoralAccord Healthcare Inc2012-10-12Not applicableCanada
Gd-gabapentincapsule300 mgoralGenmed A Division Of Pfizer Canada Inc2011-01-19Not applicableCanada
Gd-gabapentincapsule400 mgoralGenmed A Division Of Pfizer Canada Inc2011-01-19Not applicableCanada
Gd-gabapentintablet600 mgoralGenmed A Division Of Pfizer Canada Inc2011-01-19Not applicableCanada
Gd-gabapentincapsule100 mgoralGenmed A Division Of Pfizer Canada Inc2011-01-19Not applicableCanada
Gd-gabapentintablet800 mgoralGenmed A Division Of Pfizer Canada Inc2011-01-19Not applicableCanada
Gralisetablet, film coated600 mg/1oralDepomed, Inc.2011-01-28Not applicableUs
Gralisetablet, film coated600 mg/1oralbryant ranch prepack2011-01-28Not applicableUs
Gralisetablet, film coated300 mg/1oralDepomed, Inc.2011-01-28Not applicableUs
Gralisetablet, film coated600 mg/1oralUnit Dose Services2011-01-28Not applicableUs
Gralise Starter PackkitDepomed, Inc.2011-01-28Not applicableUs
Ipg-gabapentincapsule300 mgoralInternational Pharmaceutical Generics LtdNot applicableNot applicableCanada
Ipg-gabapentincapsule400 mgoralInternational Pharmaceutical Generics LtdNot applicableNot applicableCanada
Ipg-gabapentincapsule100 mgoralInternational Pharmaceutical Generics LtdNot applicableNot applicableCanada
Jamp-gabapentincapsule300 mgoralJamp Pharma Corporation2011-09-26Not applicableCanada
Jamp-gabapentincapsule400 mgoralJamp Pharma Corporation2011-09-26Not applicableCanada
Jamp-gabapentincapsule100 mgoralJamp Pharma Corporation2011-09-26Not applicableCanada
Jamp-gabapentin Tabletstablet600 mgoralJamp Pharma Corporation2013-05-01Not applicableCanada
Jamp-gabapentin Tabletstablet800 mgoralJamp Pharma Corporation2013-05-01Not applicableCanada
Mar-gabapentincapsule100 mgoralMarcan Pharmaceuticals Inc2014-01-08Not applicableCanada
Mar-gabapentincapsule300 mgoralMarcan Pharmaceuticals Inc2014-01-08Not applicableCanada
Mar-gabapentincapsule400 mgoralMarcan Pharmaceuticals Inc2014-01-08Not applicableCanada
Mar-gabapentin Tabstablet600 mgoralMarcan Pharmaceuticals IncNot applicableNot applicableCanada
Mar-gabapentin Tabstablet800 mgoralMarcan Pharmaceuticals IncNot applicableNot applicableCanada
Mint-gabapentincapsule400 mgoralMint Pharmaceuticals IncNot applicableNot applicableCanada
Mint-gabapentincapsule100 mgoralMint Pharmaceuticals IncNot applicableNot applicableCanada
Mint-gabapentincapsule300 mgoralMint Pharmaceuticals IncNot applicableNot applicableCanada
Mylan-gabapentincapsule100 mgoralMylan Pharmaceuticals Ulc2003-11-03Not applicableCanada
Mylan-gabapentintablet600 mgoralMylan Pharmaceuticals Ulc2012-11-28Not applicableCanada
Mylan-gabapentincapsule300 mgoralMylan Pharmaceuticals Ulc2003-11-03Not applicableCanada
Mylan-gabapentintablet800 mgoralMylan Pharmaceuticals Ulc2012-11-28Not applicableCanada
Mylan-gabapentincapsule400 mgoralMylan Pharmaceuticals Ulc2003-11-03Not applicableCanada
Neurontintablet, film coated800 mg/1oralParke Davis Div Of Pfizer Inc1998-10-09Not applicableUs
Neurontincapsule300 mg/1oralREMEDYREPACK INC.2012-09-17Not applicableUs
Neurontincapsule400 mg/1oralParke Davis Div Of Pfizer Inc1993-12-30Not applicableUs
Neurontintablet, film coated600 mg/1oralParke Davis Div Of Pfizer Inc1998-10-09Not applicableUs
Neurontincapsule300 mg/1oralCardinal Health1993-12-30Not applicableUs
Neurontinsolution250 mg/5mLoralParke Davis Div Of Pfizer Inc2000-03-02Not applicableUs
Neurontincapsule400 mg/1oralSTAT Rx USA LLC1993-12-30Not applicableUs
Neurontincapsule100 mg/1oralParke Davis Div Of Pfizer Inc1993-12-30Not applicableUs
Neurontincapsule300 mg/1oralParke Davis Div Of Pfizer Inc1993-12-30Not applicableUs
Neurontin 600mgtablet600 mgoralPfizer Canada Inc2000-05-01Not applicableCanada
Neurontin 800mgtablet800 mgoralPfizer Canada Inc2000-05-01Not applicableCanada
Neurontin Cap 100mgcapsule100 mgoralPfizer Canada Inc1994-12-31Not applicableCanada
Neurontin Cap 300mgcapsule300 mgoralPfizer Canada Inc1994-12-31Not applicableCanada
Neurontin Cap 400mgcapsule400 mgoralPfizer Canada Inc1994-12-31Not applicableCanada
Ntp-gabapentintablet800 mgoralTeva Canada LimitedNot applicableNot applicableCanada
Ntp-gabapentintablet600 mgoralTeva Canada LimitedNot applicableNot applicableCanada
Nu-gabapentin Capsulescapsule300 mgoralNu Pharm IncNot applicableNot applicableCanada
Nu-gabapentin Capsulescapsule400 mgoralNu Pharm IncNot applicableNot applicableCanada
Nu-gabapentin Capsulescapsule100 mgoralNu Pharm IncNot applicableNot applicableCanada
Pendo-gabapentincapsule300 mgoralPendopharm Division Of De Pharmascience IncNot applicableNot applicableCanada
PHL-gabapentintablet600 mgoralPharmel Inc2004-12-02Not applicableCanada
PHL-gabapentintablet800 mgoralPharmel Inc2004-12-02Not applicableCanada
PMS-gabapentintablet600 mgoralPharmascience Inc2004-07-28Not applicableCanada
PMS-gabapentincapsule300 mgoralPharmascience Inc2001-02-23Not applicableCanada
PMS-gabapentintablet800 mgoralPharmascience Inc2004-07-28Not applicableCanada
PMS-gabapentincapsule400 mgoralPharmascience Inc2001-02-23Not applicableCanada
PMS-gabapentincapsule100 mgoralPharmascience Inc2001-02-23Not applicableCanada
Priva-gabapentintablet600 mgoralPharmapar IncNot applicableNot applicableCanada
Priva-gabapentintablet800 mgoralPharmapar IncNot applicableNot applicableCanada
Pro-gabapentintablet800 mgoralPro Doc Limitee2008-10-27Not applicableCanada
Pro-gabapentincapsule100 mgoralPro Doc Limitee2008-10-27Not applicableCanada
Pro-gabapentincapsule300 mgoralPro Doc Limitee2008-10-27Not applicableCanada
Pro-gabapentincapsule400 mgoralPro Doc Limitee2008-10-27Not applicableCanada
Pro-gabapentintablet600 mgoralPro Doc Limitee2008-10-27Not applicableCanada
Ran-gabapentincapsule100 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-01-07Not applicableCanada
Ran-gabapentincapsule300 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-01-07Not applicableCanada
Ran-gabapentincapsule400 mgoralRanbaxy Pharmaceuticals Canada Inc.2009-01-07Not applicableCanada
Ratio-gabapentintablet600 mgoralRatiopharm Inc Division Of Teva Canada Limited2004-12-082014-09-19Canada
Ratio-gabapentincapsule100 mgoralRatiopharm Inc Division Of Teva Canada Limited2004-12-082014-09-19Canada
Ratio-gabapentintablet800 mgoralRatiopharm Inc Division Of Teva Canada Limited2004-12-082014-09-19Canada
Ratio-gabapentincapsule300 mgoralRatiopharm Inc Division Of Teva Canada Limited2004-12-082014-09-19Canada
Ratio-gabapentincapsule400 mgoralRatiopharm Inc Division Of Teva Canada Limited2004-12-082014-09-19Canada
Riva-gabapentintablet600 mgoralLaboratoire Riva Inc2004-12-03Not applicableCanada
Riva-gabapentincapsule100 mgoralLaboratoire Riva Inc2004-03-25Not applicableCanada
Riva-gabapentintablet800 mgoralLaboratoire Riva Inc2004-12-03Not applicableCanada
Riva-gabapentincapsule300 mgoralLaboratoire Riva Inc2004-03-25Not applicableCanada
Riva-gabapentincapsule400 mgoralLaboratoire Riva Inc2004-03-25Not applicableCanada
Taro-gabapentincapsule400 mgoralTaro Pharmaceuticals IncNot applicableNot applicableCanada
Taro-gabapentincapsule100 mgoralTaro Pharmaceuticals IncNot applicableNot applicableCanada
Taro-gabapentincapsule300 mgoralTaro Pharmaceuticals IncNot applicableNot applicableCanada
Teva-gabapentintablet800 mgoralTeva Canada Limited2003-06-30Not applicableCanada
Teva-gabapentintablet600 mgoralTeva Canada Limited2003-11-19Not applicableCanada
Teva-gabapentincapsule100 mgoralTeva Canada Limited2002-06-21Not applicableCanada
Teva-gabapentincapsule300 mgoralTeva Canada Limited2002-06-21Not applicableCanada
Teva-gabapentincapsule400 mgoralTeva Canada Limited2002-06-21Not applicableCanada
Van-gabapentintablet800 mgoralVanc Pharmaceuticals Inc2015-07-07Not applicableCanada
Van-gabapentincapsule100 mgoralVanc Pharmaceuticals Inc2015-06-10Not applicableCanada
Van-gabapentincapsule300 mgoralVanc Pharmaceuticals Inc2015-06-10Not applicableCanada
Van-gabapentincapsule400 mgoralVanc Pharmaceuticals Inc2015-06-10Not applicableCanada
Van-gabapentintablet600 mgoralVanc Pharmaceuticals Inc2015-07-07Not applicableCanada
Approved Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Apo-gabapentintablet600 mgoralApotex Inc2008-06-04Not applicableCanada
Apo-gabapentintablet800 mgoralApotex Inc2008-06-04Not applicableCanada
Apo-gabapentin Capsulescapsule300 mgoralApotex Inc2001-08-27Not applicableCanada
Apo-gabapentin Capsulescapsule400 mgoralApotex Inc2001-08-27Not applicableCanada
Apo-gabapentin Capsulescapsule100 mgoralApotex Inc2001-08-27Not applicableCanada
Gabapentincapsule400 mg/1oralBi Coastal Pharma International Llc2016-04-13Not applicableUs
Gabapentincapsule400 mg/1oralREMEDYREPACK INC.2013-02-15Not applicableUs
Gabapentinsolution250 mg/5mLoralHi Tech Pharmacal Co., Inc.2011-02-23Not applicableUs
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2014-01-30Not applicableUs
Gabapentintablet800 mg/1oralPhysicians Total Care, Inc.2004-12-16Not applicableUs
Gabapentintablet, film coated600 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2004-02-14Not applicableUs
Gabapentincapsule300 mg/1oralCardinal Health2011-01-29Not applicableUs
Gabapentinsolution250 mg/5mLoralKiel Laboratories, Inc.2012-05-01Not applicableUs
Gabapentintablet, film coated600 mg/1oralCardinal Health2014-11-03Not applicableUs
Gabapentincapsule300 mg/1oralApotex Corp.2005-04-06Not applicableUs
Gabapentincapsule300 mg/1oralDIRECT RX2015-01-01Not applicableUs
Gabapentincapsule400 mg/1oralProficient Rx LP2010-05-17Not applicableUs
Gabapentincapsule300 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2004-10-04Not applicableUs
Gabapentincapsule300 mg/1oralBlenheim Pharmacal, Inc.2014-04-04Not applicableUs
Gabapentincapsule300 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-24Not applicableUs
Gabapentincapsule100 mg/1oralNorth Star Rx Llc2008-01-31Not applicableUs
Gabapentincapsule400 mg/1oralContract Pharmacy Services Pa2010-07-19Not applicableUs
Gabapentintablet800 mg/1oralCamber Pharmaceuticals, Inc.2012-10-29Not applicableUs
Gabapentintablet, film coated600 mg/1oralZydus Pharmaceuticals (USA) Inc.2012-10-16Not applicableUs
Gabapentintablet600 mg/1oralRebel Distributors Corp2011-02-09Not applicableUs
Gabapentintablet, film coated600 mg/1oralPreferred Pharmaceuticals, Inc.2012-01-27Not applicableUs
Gabapentincapsule400 mg/1oralWest ward Pharmaceutical Corp2007-07-09Not applicableUs
Gabapentincapsule100 mg/1oralPd Rx Pharmaceuticals, Inc.2009-11-24Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2016-01-08Not applicableUs
Gabapentincapsule400 mg/1oralScie Gen Pharmaceuticals, Inc.2016-02-18Not applicableUs
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2011-06-07Not applicableUs
Gabapentincapsule400 mg/1oralAvera Mc Kennan Hospital2015-03-02Not applicableUs
Gabapentincapsule300 mg/1oralSafecor Health, LLC2014-09-30Not applicableUs
Gabapentincapsule300 mg/1oralCardinal Health2005-04-06Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2011-05-19Not applicableUs
Gabapentincapsule300 mg/300mgoralWestminster Pharmaceuticals, Llc2016-04-01Not applicableUs
Gabapentintablet600 mg/1oralLake Erie Medica & Surgical Supply DBA Quality Care Products LLC2011-11-04Not applicableUs
Gabapentincapsule100 mg/1oralBreckenridge Pharmaceutical, Inc.2012-10-15Not applicableUs
Gabapentincapsule100 mg/1oralH.J. Harkins Company, Inc.2010-05-17Not applicableUs
Gabapentincapsule100 mg/1oralMylan Pharmaceuticals Inc.2011-02-14Not applicableUs
Gabapentincapsule400 mg/1oralCardinal Health2007-06-20Not applicableUs
Gabapentintablet, film coated600 mg/1oralClinical Solutions Wholesale2006-08-24Not applicableUs
Gabapentintablet, film coated600 mg/1oralCardinal Health2004-02-14Not applicableUs
Gabapentincapsule400 mg/1oralGolden State Medical Supply, Inc.2013-03-08Not applicableUs
Gabapentintablet, film coated800 mg/1oralSt Marys Medical Park Pharmacy2010-12-03Not applicableUs
Gabapentincapsule300 mg/1oralSun Pharmaceutical Industries Limited2006-08-24Not applicableUs
Gabapentincapsule400 mg/1oralRanbaxy Pharmaceuticals Inc.2005-11-02Not applicableUs
Gabapentincapsule400 mg/1oralMajor Pharmaceuticals2005-04-06Not applicableUs
Gabapentincapsule300 mg/1oralReady Meds2010-05-17Not applicableUs
Gabapentincapsule100 mg/1oralSTAT Rx USA LLC2004-10-04Not applicableUs
Gabapentintablet, film coated600 mg/1oralAurobindo Pharma Limited2011-10-06Not applicableUs
Gabapentincapsule100 mg/1oralMARKSANS PHARMA LIMITED2011-02-28Not applicableUs
Gabapentintablet, film coated600 mg/1oralAmerican Health Packaging2012-08-31Not applicableUs
Gabapentincapsule300 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2009-11-24Not applicableUs
Gabapentincapsule100 mg/1oralPreferred Pharmaceuticals, Inc.2010-05-17Not applicableUs
Gabapentintablet600 mg/1oralTeva Pharmaceuticals USA Inc2008-07-11Not applicableUs
Gabapentincapsule300 mg/1oralWestwood Manufacturing2010-01-23Not applicableUs
Gabapentintablet, film coated600 mg/1oralAllied Pharma Inc2013-06-02Not applicableUs
Gabapentintablet, film coated600 mg/1oralAphena Pharma Solutions Tennessee, Llc2012-11-02Not applicableUs
Gabapentintablet800 mg/1oralProficient Rx LP2012-10-29Not applicableUs
Gabapentincapsule100 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-11-24Not applicableUs
Gabapentincapsule400 mg/1oralBlenheim Pharmacal, Inc.2010-05-17Not applicableUs
Gabapentintablet, film coated800 mg/1oralCadila Healthcare Limited2012-10-16Not applicableUs
Gabapentincapsule300 mg/1oralRebel Distributors Corp.2006-08-29Not applicableUs
Gabapentincapsule400 mg/1oralAphena Pharma Solutions Tennessee, Llc2004-10-04Not applicableUs
Gabapentintablet, film coated600 mg/1oralAidarex Pharmaceuticals LLC2011-10-06Not applicableUs
Gabapentincapsule100 mg/1oralKeltman Pharmaceuticals Inc.2009-12-15Not applicableUs
Gabapentincapsule100 mg/1oralAv Kare, Inc.2012-05-04Not applicableUs
Gabapentincapsule300 mg/1oralMc Kesson Contract Packaging2011-08-29Not applicableUs
Gabapentincapsule300 mg/1oralActavis Pharma, Inc.2004-10-04Not applicableUs
Gabapentincapsule100 mg/1oralAphena Pharma Solutions Tennessee, Inc.2010-05-17Not applicableUs
Gabapentincapsule400 mg/1oralMedsource Pharmaceuticals2010-05-17Not applicableUs
Gabapentintablet800 mg/1oralDIRECT RX2016-03-16Not applicableUs
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2011-07-19Not applicableUs
Gabapentincapsule300 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-11-24Not applicableUs
Gabapentincapsule400 mg/1oralTIME CAP LABORATORIES, INC2015-12-30Not applicableUs
Gabapentincapsule300 mg/1oralUnit Dose Services2010-05-17Not applicableUs
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2014-05-22Not applicableUs
Gabapentincapsule300 mg/1oralCardinal Health2005-04-06Not applicableUs
Gabapentincapsule100 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-03-17Not applicableUs
Gabapentincapsule400 mg/1oralCardinal Health2010-01-23Not applicableUs
Gabapentintablet, film coated800 mg/1oralHikma Pharmaceutical2011-07-21Not applicableUs
Gabapentintablet800 mg/1oralLake Erie Medical DBA Quality Care Products LLC2008-08-01Not applicableUs
Gabapentintablet, film coated400 mg/1oralApotex Corp.2006-10-10Not applicableUs
Gabapentincapsule400 mg/1oralDIRECT RX2015-01-01Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2015-12-30Not applicableUs
Gabapentintablet, film coated600 mg/1oralProficient Rx2004-02-14Not applicableUs
Gabapentintablet600 mg/1oralbryant ranch prepack2006-04-01Not applicableUs
Gabapentincapsule300 mg/1oralBlenheim Pharmacal, Inc.2010-08-20Not applicableUs
Gabapentincapsule300 mg/1oralTYA Pharmaceuticals2010-05-17Not applicableUs
Gabapentincapsule400 mg/1oralSTAT Rx USA LLC2009-11-24Not applicableUs
Gabapentincapsule300 mg/1oralMed Vantx Inc.2011-09-13Not applicableUs
Gabapentincapsule300 mg/1oralCamber Pharmaceuticals Inc.2010-05-17Not applicableUs
Gabapentincapsule100 mg/1oralAmerican Health Packaging2014-07-01Not applicableUs
Gabapentincapsule400 mg/1oralLake Erie Medical DBA Quality Care Products LLC2006-08-24Not applicableUs
Gabapentintablet800 mg/1oralPreferred Pharmaceuticals, Inc.2015-01-05Not applicableUs
Gabapentincapsule400 mg/1oralWest ward Pharmaceutical Corp2007-07-09Not applicableUs
Gabapentincapsule400 mg/1oralPd Rx Pharmaceuticals, Inc.2004-10-04Not applicableUs
Gabapentincapsule400 mg/1oralExelan Pharmaceuticals, Inc.2010-04-26Not applicableUs
Gabapentintablet, film coated600 mg/1oralSolco healthcare U.S., LLC2014-11-01Not applicableUs
Gabapentincapsule300 mg/1oralPd Rx Pharmaceuticals, Inc.2008-01-31Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2011-03-01Not applicableUs
Gabapentincapsule100 mg/1oralPd Rx Pharmaceuticals, Inc.2008-01-31Not applicableUs
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2012-03-16Not applicableUs
Gabapentincapsule400 mg/1oralAv Pak2014-09-15Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2013-05-15Not applicableUs
Gabapentincapsule300 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-24Not applicableUs
Gabapentincapsule100 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2003-09-12Not applicableUs
Gabapentincapsule400 mg/1oralCardinal Health2004-12-10Not applicableUs
Gabapentincapsule100 mg/1oralClinical Solutions Wholesale, Llc2009-11-24Not applicableUs
Gabapentincapsule300 mg/1oralCardinal Health2009-11-24Not applicableUs
Gabapentintablet, film coated600 mg/1oralGolden State Medical Supply, Inc.2006-09-15Not applicableUs
Gabapentintablet600 mg/1oralAscend Laboratories, LLC2015-11-01Not applicableUs
Gabapentincapsule300 mg/1oralPharmaceutica North America, Inc.2014-02-12Not applicableUs
Gabapentincapsule100 mg/1oralDepartment Of State Health Services, Pharmacy Branch2011-01-29Not applicableUs
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2011-06-27Not applicableUs
Gabapentincapsule300 mg/1oralLake Erie Medical DBA Quality Care Products LLC2005-04-06Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2013-02-08Not applicableUs
Gabapentincapsule100 mg/1oralUnit Dose Services2010-05-17Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2014-02-18Not applicableUs
Gabapentintablet600 mg/1oralPhysicians Total Care, Inc.2005-02-14Not applicableUs
Gabapentintablet, film coated800 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2004-10-21Not applicableUs
Gabapentincapsule400 mg/1oralCardinal Health2011-01-29Not applicableUs
Gabapentincapsule100 mg/1oralHikma Pharmaceutical2007-07-09Not applicableUs
Gabapentincapsule300 mg/1oralPd Rx Pharmaceuticals, Inc.2010-05-17Not applicableUs
Gabapentincapsule400 mg/1oralApotex Corp.2005-04-06Not applicableUs
Gabapentintablet600 1/1oralDIRECT RX2014-01-01Not applicableUs
Gabapentintablet600 mg/1oralProficient Rx LP2006-04-01Not applicableUs
Gabapentincapsule400 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2004-10-04Not applicableUs
Gabapentintablet600 mg/1oralBlenheim Pharmacal, Inc.2014-02-07Not applicableUs
Gabapentincapsule400 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-24Not applicableUs
Gabapentincapsule300 mg/1oralNorth Star Rx Llc2008-01-31Not applicableUs
Gabapentincapsule300 mg/1oralContract Pharmacy Services Pa2010-04-12Not applicableUs
Gabapentincapsule100 mg/1oralAidarex Pharmaceuticals LLC2009-11-24Not applicableUs
Gabapentintablet, film coated800 mg/1oralZydus Pharmaceuticals (USA) Inc.2012-10-16Not applicableUs
Gabapentincapsule100 mg/1oralRebel Distributors Corp2009-11-24Not applicableUs
Gabapentincapsule300 mg/1oralAvera Mc Kennan Hospital2015-09-16Not applicableUs
Gabapentintablet, film coated600 mg/1oralActavis Pharma, Inc.2004-02-14Not applicableUs
Gabapentintablet, film coated800 mg/1oralPd Rx Pharmaceuticals, Inc.2012-10-16Not applicableUs
Gabapentincapsule300 mg/1oralPreferred Pharmaceuticals, Inc.2010-05-17Not applicableUs
Gabapentintablet800 mg/1oralTeva Pharmaceuticals USA Inc2008-08-01Not applicableUs
Gabapentincapsule100 mg/1oralSTAT Rx USA LLC2009-11-24Not applicableUs
Gabapentintablet, film coated800 mg/1oralAllied Pharma Inc2013-06-02Not applicableUs
Gabapentincapsule100 mg/1oralSolco healthcare U.S., LLC2012-10-15Not applicableUs
Gabapentincapsule300 mg/1oralLake Erie Medical DBA Quality Care Products LLC2009-11-24Not applicableUs
Gabapentincapsule100 mg/1oralSafecor Health, LLC2014-09-30Not applicableUs
Gabapentincapsule100 mg/1oralAscend Laboratories, LLC2011-01-29Not applicableUs
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2011-09-09Not applicableUs
Gabapentincapsule400 mg/400mgoralWestminster Pharmaceuticals, Llc2016-04-01Not applicableUs
Gabapentintablet, film coated800 mg/1oralLake Erie Medical & Surgical S6758upply DBA Quality Care Products LLC2010-12-06Not applicableUs
Gabapentincapsule300 mg/1oralBreckenridge Pharmaceutical, Inc.2012-10-15Not applicableUs
Gabapentintablet800 mg/1oralH.J. Harkins Company, Inc.2006-04-01Not applicableUs
Gabapentincapsule300 mg/1oralMylan Pharmaceuticals Inc.2011-02-14Not applicableUs
Gabapentincapsule300 mg/1oralCardinal Health2007-06-20Not applicableUs
Gabapentintablet, film coated600 mg/1oralClinical Solutions Wholesale2006-08-24Not applicableUs
Gabapentincapsule100 mg/1oralCardinal Health2004-04-28Not applicableUs
Gabapentincapsule100 mg/1oralGolden State Medical Supply, Inc.2010-05-17Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2015-02-25Not applicableUs
Gabapentincapsule400 mg/1oralSun Pharmaceutical Industries Limited2006-08-24Not applicableUs
Gabapentincapsule100 mg/1oralbryant ranch prepack2009-11-24Not applicableUs
Gabapentincapsule100 mg/1oralMajor Pharmaceuticals2010-05-10Not applicableUs
Gabapentintablet600 mg/1oralTYA Pharmaceuticals2006-04-01Not applicableUs
Gabapentincapsule300 mg/1oralSTAT Rx USA LLC2004-10-04Not applicableUs
Gabapentintablet, film coated800 mg/1oralAurobindo Pharma Limited2011-10-06Not applicableUs
Gabapentincapsule300 mg/1oralMARKSANS PHARMA LIMITED2011-02-28Not applicableUs
Gabapentintablet, film coated800 mg/1oralAmerican Health Packaging2012-08-31Not applicableUs
Gabapentincapsule100 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2010-05-17Not applicableUs
Gabapentintablet, film coated600 mg/1oralApotex Corp.2006-09-15Not applicableUs
Gabapentintablet800 mg/1oralDIRECT RX2015-11-25Not applicableUs
Gabapentincapsule100 mg/1oralProficient Rx LP2010-05-17Not applicableUs
Gabapentincapsule300 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-11-24Not applicableUs
Gabapentincapsule100 mg/1oralActavis Pharma Manufacturing Pvt Ltd. (SOD)2010-01-232016-03-12Us
Gabapentincapsule100 mg/1oralAurobindo Pharma Limited2008-01-31Not applicableUs
Gabapentintablet, film coated600 mg/1oralRebel Distributors Corp.2006-08-24Not applicableUs
Gabapentincapsule100 mg/1oralAphena Pharma Solutions Tennessee, Llc2004-10-04Not applicableUs
Gabapentintablet, film coated800 mg/1oralAidarex Pharmaceuticals LLC2011-10-06Not applicableUs
Gabapentintablet600 mg/1oralGlenmark Pharmaceuticals Inc., Usa2006-04-01Not applicableUs
Gabapentincapsule300 mg/1oralAv Kare, Inc.2012-05-04Not applicableUs
Gabapentincapsule400 mg/1oralMc Kesson Contract Packaging2011-12-09Not applicableUs
Gabapentincapsule400 mg/1oralActavis Pharma, Inc.2004-10-04Not applicableUs
Gabapentincapsule100 mg/1oralAphena Pharma Solutions Tennessee, Llc2008-01-31Not applicableUs
Gabapentincapsule100 mg/1oralActavis Pharma, Inc.2014-03-17Not applicableUs
Gabapentintablet800 mg/1oralREMEDYREPACK INC.2014-07-07Not applicableUs
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2011-07-25Not applicableUs
Gabapentincapsule100 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-11-24Not applicableUs
Gabapentincapsule300 mg/1oralLake Erie Medical DBA Quality Care Products LLC2010-09-17Not applicableUs
Gabapentintablet800 mg/1oralUnit Dose Services2008-08-01Not applicableUs
Gabapentincapsule100 mg/1oralLucid Pharma Llc2008-01-31Not applicableUs
Gabapentincapsule100 mg/1oralCardinal Health2010-05-10Not applicableUs
Gabapentincapsule300 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-01-23Not applicableUs
Gabapentintablet, film coated600 mg/1oralCardinal Health2012-08-31Not applicableUs
Gabapentintablet, film coated600 mg/1001oralHikma Pharmaceutical2011-07-21Not applicableUs
Gabapentintablet800 mg/1oralClinical Solutions Wholesale, Llc2008-08-01Not applicableUs
Gabapentincapsule400 mg/1oralClinical Solutions Wholesale, Llc2011-01-29Not applicableUs
Gabapentincapsule300 mg/1oralCardinal Health2014-07-01Not applicableUs
Gabapentintablet, film coated600 mg/1oralGolden State Medical Supply, Inc.2006-09-15Not applicableUs
Gabapentincapsule400 mg/1oralDIRECT RX2014-01-01Not applicableUs
Gabapentintablet800 mg/1oralProficient Rx LP2006-04-01Not applicableUs
Gabapentintablet, film coated800 mg/1oralbryant ranch prepack2006-08-24Not applicableUs
Gabapentincapsule100 mg/1oralBlenheim Pharmacal, Inc.2010-10-08Not applicableUs
Gabapentincapsule100 mg/1oralTYA Pharmaceuticals2010-01-23Not applicableUs
Gabapentintablet, film coated600 mg/1oralNorth Star Rx Llc2011-10-06Not applicableUs
Gabapentincapsule300 mg/1oralDispensing Solutions, Inc.2007-07-09Not applicableUs
Gabapentincapsule400 mg/1oralCamber Pharmaceuticals Inc.2010-05-17Not applicableUs
Gabapentintablet, film coated600 mg/1oralAmerican Health Packaging2014-11-03Not applicableUs
Gabapentinsolution250 mg/5mLoralAcella Pharmaceuticals, LLC2012-10-01Not applicableUs
Gabapentincapsule400 mg/1oralPreferred Pharmaceuticals, Inc.2014-02-28Not applicableUs
Gabapentincapsule100 mg/1oralWest ward Pharmaceutical Corp2007-07-09Not applicableUs
Gabapentintablet, film coated800 mg/1oralPd Rx Pharmaceuticals, Inc.2004-02-14Not applicableUs
Gabapentintablet, film coated600 mg/1oralExelan Pharmaceuticals Inc.2012-11-02Not applicableUs
Gabapentintablet, film coated800 mg/1oralSolco healthcare U.S., LLC2014-11-01Not applicableUs
Gabapentincapsule100 mg/1oralScie Gen Pharmaceuticals, Inc.2016-02-18Not applicableUs
Gabapentintablet800 mg/1oralREMEDYREPACK INC.2011-05-25Not applicableUs
Gabapentincapsule100 mg/1oralBi Coastal Pharma International Llc2016-04-13Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2012-03-22Not applicableUs
Gabapentintablet, film coated600 mg/1oralAv Pak2015-02-13Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2013-05-22Not applicableUs
Gabapentincapsule400 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-24Not applicableUs
Gabapentincapsule400 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2003-09-12Not applicableUs
Gabapentincapsule100 mg/1oralCardinal Health2011-01-29Not applicableUs
Gabapentincapsule400 mg/1oralKeltman Pharmaceuticals Inc.2009-12-15Not applicableUs
Gabapentintablet800 mg/1oralRebel Distributors Corp2011-02-09Not applicableUs
Gabapentincapsule300 mg/300mgoralAlivio Medical Products, Llc2015-10-01Not applicableUs
Gabapentintablet, film coated800 mg/1oralActavis Pharma, Inc.2004-02-14Not applicableUs
Gabapentincapsule300 mg/1oralAphena Pharma Solutions Tennessee, Inc.2010-05-17Not applicableUs
Gabapentintablet800 mg/1oralAscend Laboratories, LLC2015-11-01Not applicableUs
Gabapentincapsule300 mg/1oralMedsource Pharmaceuticals2009-11-24Not applicableUs
Gabapentincapsule300 mg/1oralDepartment Of State Health Services, Pharmacy Branch2010-01-23Not applicableUs
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2011-07-08Not applicableUs
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2016-04-08Not applicableUs
Gabapentincapsule100 mg/1oralTIME CAP LABORATORIES, INC2015-12-30Not applicableUs
Gabapentintablet, film coated600 mg/1oralUnit Dose Services2006-08-24Not applicableUs
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2014-03-04Not applicableUs
Gabapentincapsule100 mg/1oralPhysicians Total Care, Inc.2009-09-24Not applicableUs
Gabapentincapsule300 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-01-23Not applicableUs
Gabapentincapsule100 mg/1oralCardinal Health2010-01-23Not applicableUs
Gabapentincapsule300 mg/1oralHikma Pharmaceutical2007-07-09Not applicableUs
Gabapentincapsule100 mg/1oralPd Rx Pharmaceuticals, Inc.2004-10-04Not applicableUs
Gabapentintablet, film coated100 mg/1oralApotex Corp.2006-10-10Not applicableUs
Gabapentintablet, film coated800 mg/1oralDIRECT RX2014-01-01Not applicableUs
Gabapentintablet, film coated800 mg/1oralProficient Rx LP2011-10-06Not applicableUs
Gabapentintablet, film coated600 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2004-02-14Not applicableUs
Gabapentincapsule400 mg/1oralBlenheim Pharmacal, Inc.2014-04-04Not applicableUs
Gabapentinsolution250 mg/5mLoralAmneal Pharmaceuticals of New York, LLC2011-09-30Not applicableUs
Gabapentincapsule400 mg/1oralNorth Star Rx Llc2008-01-31Not applicableUs
Gabapentintablet600 mg/1oralContract Pharmacy Services Pa2009-08-30Not applicableUs
Gabapentincapsule300 mg/1oralAidarex Pharmaceuticals LLC2009-11-24Not applicableUs
Gabapentincapsule300 mg/1oralMed Vantx, Inc.2004-10-04Not applicableUs
Gabapentincapsule400 mg/1oralMARKSANS PHARMA LIMITED2011-02-28Not applicableUs
Gabapentincapsule300 mg/1oralAmerican Health Packaging2014-07-01Not applicableUs
Gabapentincapsule400 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2010-05-17Not applicableUs
Gabapentintablet600 mg/1oralPreferred Pharmaceuticals, Inc.2015-04-15Not applicableUs
Gabapentincapsule100 mg/1oralWest ward Pharmaceutical Corp2007-07-09Not applicableUs
Gabapentincapsule300 mg/1oralSTAT Rx USA LLC2009-11-24Not applicableUs
Gabapentincapsule100 mg/1oralExelan Pharmaceuticals, Inc.2010-04-26Not applicableUs
Gabapentincapsule300 mg/1oralSolco healthcare U.S., LLC2012-10-15Not applicableUs
Gabapentintablet600 mg/1oralScie Gen Pharmaceuticals, Inc.2015-11-24Not applicableUs
Gabapentincapsule400 mg/1oralSafecor Health, LLC2014-09-30Not applicableUs
Gabapentincapsule300 mg/1oralAscend Laboratories, LLC2011-01-29Not applicableUs
Gabapentintablet800 mg/1oralREMEDYREPACK INC.2011-12-02Not applicableUs
Gabapentintablet600 mg/600mgoralWestminster Pharmaceuticals, Llc2016-04-11Not applicableUs
Gabapentincapsule100 mg/1oralAv Pak2014-09-152016-03-15Us
Gabapentincapsule400 mg/1oralBreckenridge Pharmaceutical, Inc.2012-10-15Not applicableUs
Gabapentintablet600 mg/1oralH.J. Harkins Company, Inc.2006-04-01Not applicableUs
Gabapentincapsule400 mg/1oralMylan Pharmaceuticals Inc.2011-02-14Not applicableUs
Gabapentincapsule100 mg/1oralCardinal Health2004-12-10Not applicableUs
Gabapentincapsule300 mg/1oralClinical Solutions Wholesale2011-01-29Not applicableUs
Gabapentincapsule300 mg/1oralCardinal Health2011-04-01Not applicableUs
Gabapentincapsule300 mg/1oralGolden State Medical Supply, Inc.2010-05-17Not applicableUs
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2015-04-16Not applicableUs
Gabapentintablet, film coated600 mg/1oralSun Pharmaceutical Industries Limited2006-08-24Not applicableUs
Gabapentincapsule400 mg/1oralbryant ranch prepack2010-05-17Not applicableUs
Gabapentincapsule300 mg/1oralMajor Pharmaceuticals2010-05-10Not applicableUs
Gabapentincapsule300 mg/1oralTYA Pharmaceuticals2006-08-24Not applicableUs
Gabapentintablet, film coated600 mg/1oralSTAT Rx USA LLC2004-02-14Not applicableUs
Gabapentincapsule100 mg/1oralMajor Pharmaceuticals2005-04-06Not applicableUs
Gabapentincapsule400 mg/1oralCardinal Health2012-03-05Not applicableUs
Gabapentincapsule100 mg/1oralGolden State Medical Supply, Inc.2013-03-08Not applicableUs
Gabapentincapsule100 mg/1oralClinical Solutions Wholesale, Llc2011-01-29Not applicableUs
Gabapentintablet, film coated600 mg/1oralApotex Corp.2006-09-152016-03-29Us
Gabapentincapsule300 mg/1oralDIRECT RX2014-01-01Not applicableUs
Gabapentincapsule100 mg/1oralRanbaxy Pharmaceuticals Inc.2005-11-02Not applicableUs
Gabapentincapsule400 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-11-24Not applicableUs
Gabapentincapsule300 mg/1oralActavis Pharma Manufacturing Pvt Ltd. (SOD)2010-01-232016-03-12Us
Gabapentincapsule300 mg/1oralAurobindo Pharma Limited2008-01-31Not applicableUs
Gabapentintablet, film coated800 mg/1oralRebel Distributors Corp.2006-08-24Not applicableUs
Gabapentintablet, film coated600 mg/1oralBlue Point Laboratories2013-07-24Not applicableUs
Gabapentincapsule300 mg/1oralRx Change Co.2014-10-26Not applicableUs
Gabapentintablet800 mg/1oralGlenmark Pharmaceuticals Inc., Usa2006-04-01Not applicableUs
Gabapentincapsule400 mg/1oralAv Kare, Inc.2012-05-04Not applicableUs
Gabapentintablet, film coated600 mg/1oralMc Kesson Contract Packaging2011-11-09Not applicableUs
Gabapentintablet600 mg/1oralMylan Pharmaceuticals Inc.2012-08-31Not applicableUs
Gabapentincapsule300 mg/1oralAphena Pharma Solutions Tennessee, Llc2008-01-31Not applicableUs
Gabapentincapsule300 mg/1oralActavis Pharma, Inc.2010-01-23Not applicableUs
Gabapentincapsule400 mg/1oralCardinal Health2005-04-06Not applicableUs
Gabapentintablet800 mg/1oralREMEDYREPACK INC.2011-07-28Not applicableUs
Gabapentincapsule400 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2009-11-24Not applicableUs
Gabapentincapsule400 mg/1oralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2010-11-04Not applicableUs
Gabapentincapsule300 mg/1oralNorthwind Pharmaceuticals2014-12-23Not applicableUs
Gabapentincapsule300 mg/1oralLucid Pharma Llc2008-01-31Not applicableUs
Gabapentincapsule300 mg/1oralCardinal Health2010-05-10Not applicableUs
Gabapentincapsule300 mg/1oralPhysicians Total Care, Inc.2006-08-29Not applicableUs
Gabapentincapsule300 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2003-09-12Not applicableUs
Gabapentincapsule100 mg/1oralCardinal Health2011-01-29Not applicableUs
Gabapentincapsule300 mg/1oralNew Horizon Rx Group, LLC2013-08-25Not applicableUs
Gabapentincapsule100 mg/1oralCardinal Health2014-07-01Not applicableUs
Gabapentincapsule100 mg/1oralApotex Corp.2005-04-06Not applicableUs
Gabapentincapsule100 mg/1oralDIRECT RX2015-01-01Not applicableUs
Gabapentincapsule300 mg/1oralProficient Rx LP2010-05-17Not applicableUs
Gabapentincapsule100 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2004-10-04Not applicableUs
Gabapentincapsule300 mg/1oralBlenheim Pharmacal, Inc.2010-01-04Not applicableUs
Gabapentincapsule100 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-24Not applicableUs
Gabapentintablet, film coated800 mg/1oralNorth Star Rx Llc2011-10-06Not applicableUs
Gabapentincapsule100 mg/1oralDispensing Solutions, Inc.2007-07-09Not applicableUs
Gabapentintablet600 mg/1oralCamber Pharmaceuticals, Inc.2012-10-29Not applicableUs
Gabapentintablet, film coated800 mg/1oralAmerican Health Packaging2014-09-01Not applicableUs
Gabapentincapsule300 mg/1oralRebel Distributors Corp2010-05-17Not applicableUs
Gabapentintablet800 mg/1oralPreferred Pharmaceuticals Inc.2015-08-20Not applicableUs
Gabapentincapsule300 mg/1oralWest ward Pharmaceutical Corp2007-07-09Not applicableUs
Gabapentincapsule300 mg/1oralPd Rx Pharmaceuticals, Inc.2009-11-24Not applicableUs
Gabapentintablet, film coated800 mg/1oralExelan Pharmaceuticals Inc.2012-11-02Not applicableUs
Gabapentincapsule300 mg/1oralPharmaceutica North America, Inc.2012-08-09Not applicableUs
Gabapentincapsule300 mg/1oralScie Gen Pharmaceuticals, Inc.2016-02-18Not applicableUs
Gabapentincapsule400 mg/1oralREMEDYREPACK INC.2011-03-31Not applicableUs
Gabapentincapsule300 mg/1oralBi Coastal Pharma International Llc2016-04-13Not applicableUs
Gabapentincapsule300 mg/1oralREMEDYREPACK INC.2012-03-23Not applicableUs
Gabapentintablet, film coated800 mg/1oralAv Pak2015-02-13Not applicableUs
Gabapentintablet, film coated800 mg/1oralREMEDYREPACK INC.2014-01-09Not applicableUs
Gabapentintablet, film coated600 mg/1oralCadila Healthcare Limited2012-10-16Not applicableUs
Gabapentincapsule100 mg/1oralRebel Distributors Corp.2009-09-24Not applicableUs
Gabapentincapsule300 mg/1oralAphena Pharma Solutions Tennessee, Llc2004-10-04Not applicableUs
Gabapentincapsule400 mg/1oralAidarex Pharmaceuticals LLC2009-11-24Not applicableUs
Gabapentincapsule300 mg/1oralKeltman Pharmaceuticals Inc.2009-12-15Not applicableUs
Gabapentincapsule400 mg/1oralRebel Distributors Corp2009-11-24Not applicableUs
Gabapentincapsule100 mg/1oralMc Kesson Contract Packaging2011-08-29Not applicableUs
Gabapentincapsule100 mg/1oralActavis Pharma, Inc.2004-10-04Not applicableUs
Gabapentincapsule400 mg/1oralAphena Pharma Solutions Tennessee, Inc.2010-05-17Not applicableUs
Gabapentintablet600 mg/1oralMedsource Pharmaceuticals2006-04-01Not applicableUs
Gabapentincapsule400 mg/1oralCarilion Materials Management2004-10-04Not applicableUs
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2011-07-11Not applicableUs
Gabapentincapsule300 mg/1oralDIRECT RX2016-03-30Not applicableUs
Gabapentincapsule300 mg/1oralTIME CAP LABORATORIES, INC2015-12-30Not applicableUs
Gabapentincapsule100 mg/1oralUnit Dose Services2009-11-24Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2014-03-04Not applicableUs
Gabapentincapsule400 mg/1oralPhysicians Total Care, Inc.2008-11-07Not applicableUs
Gabapentincapsule400 mg/1oralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-03-17Not applicableUs
Gabapentincapsule300 mg/1oralCardinal Health2010-01-23Not applicableUs
Gabapentincapsule400 mg/1oralHikma Pharmaceutical2007-07-09Not applicableUs
Gabapentintablet600 mg/1oralPd Rx Pharmaceuticals, Inc.2006-04-01Not applicableUs
Gabapentintablet, film coated300 mg/1oralApotex Corp.2006-10-10Not applicableUs
Gabapentincapsule100 mg/1oralDIRECT RX2015-01-01Not applicableUs
Gabapentintablet600 mg/1oralProficient Rx LP2012-10-29Not applicableUs
Gabapentintablet, film coated600 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2012-10-16Not applicableUs
Gabapentintablet800 mg/1oralBlenheim Pharmacal, Inc.2006-04-01Not applicableUs
Gabapentincapsule300 mg/1oralbryant ranch prepack2010-05-17Not applicableUs
Gabapentincapsule400 mg/1oralMajor Pharmaceuticals2010-05-10Not applicableUs
Gabapentincapsule100 mg/1oralTYA Pharmaceuticals2010-05-17Not applicableUs
Gabapentintablet, film coated800 mg/1oralSTAT Rx USA LLC2006-08-24Not applicableUs
Gabapentincapsule300 mg/1oralMed Vantx, Inc.2008-01-31Not applicableUs
Gabapentincapsule100 mg/1oralCamber Pharmaceuticals Inc.2010-05-17Not applicableUs
Gabapentincapsule400 mg/1oralAmerican Health Packaging2014-07-01Not applicableUs
Gabapentintablet600 mg/1oralLake Erie Medical DBA Quality Care Products LLC2008-07-11Not applicableUs
Gabapentincapsule100 mg/1oralPreferred Pharmaceuticals, Inc.2015-04-13Not applicableUs
Gabapentincapsule300 mg/1oralWest ward Pharmaceutical Corp2007-07-09Not applicableUs
Gabapentintablet600 mg/1oralSTAT Rx USA LLC2009-06-09Not applicableUs
Gabapentincapsule300 mg/1oralExelan Pharmaceuticals, Inc.2010-04-26Not applicableUs
Gabapentincapsule400 mg/1oralSolco healthcare U.S., LLC2012-10-15Not applicableUs
Gabapentintablet800 mg/1oralScie Gen Pharmaceuticals, Inc.2015-11-24Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2011-04-19Not applicableUs
Gabapentincapsule400 mg/1oralAscend Laboratories, LLC2011-01-29Not applicableUs
Gabapentintablet600 mg/1oralREMEDYREPACK INC.2012-03-07Not applicableUs
Gabapentintablet800 mg/800mgoralWestminster Pharmaceuticals, Llc2016-04-11Not applicableUs
Gabapentincapsule300 mg/1oralAv Pak2014-09-15Not applicableUs
Gabapentincapsule100 mg/1oralREMEDYREPACK INC.2012-09-20Not applicableUs
Gabapentincapsule100 mg/1oralAmneal Pharmaceuticals of New York, LLC2009-11-24Not applicableUs
Gabapentincapsule300 mg/1oralLiberty Pharmaceuticals, Inc.2009-11-24Not applicableUs
Gabapentintablet600 mg/1oralCardinal Health2007-08-02Not applicableUs
Gabapentincapsule300 mg/1oralClinical Solutions Wholesale2011-01-29Not applicableUs
Gabapentincapsule400 mg/1oralCardinal Health2009-11-24Not applicableUs
Gabapentincapsule400 mg/1oralGolden State Medical Supply, Inc.2010-05-17Not applicableUs
Gabapentincapsule400 mg/1oralREMEDYREPACK INC.2015-06-09Not applicableUs
Gabapentintablet, film coated800 mg/1oralSun Pharmaceutical Industries Limited2006-08-24Not applicableUs
Gabapentincapsule400 mg/1oralLucid Pharma Llc2008-01-31Not applicableUs
Gabapentincapsule400 mg/1oralCardinal Health2010-05-10Not applicableUs
Gabapentincapsule300 mg/1oralMajor Pharmaceuticals2005-04-06Not applicableUs
Gabapentincapsule100 mg/1oralCardinal Health2012-03-05Not applicableUs
Gabapentincapsule300 mg/1oralGolden State Medical Supply, Inc.2013-03-08Not applicableUs
Gabapentincapsule100 mg/1oralClinical Solutions Wholesale2009-11-24Not applicableUs
Gabapentincapsule400 mg/1oralSt Marys Medical Park Pharmacy2010-12-01Not applicableUs
Gabapentincapsule100 mg/1oralSun Pharmaceutical Industries Limited2006-08-24Not applicableUs
Gabapentincapsule300 mg/1oralRanbaxy Pharmaceuticals Inc.2005-11-02Not applicableUs
Gabapentincapsule300 mg/1oralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2012-10-29Not applicableUs
Gabapentincapsule400 mg/1oralActavis Pharma Manufacturing Pvt Ltd. (SOD)2010-01-232016-03-12Us
Gabapentincapsule400 mg/1oralAurobindo Pharma Limited2008-01-31Not applicableUs
Gabapentincapsule400 mg/1oralRebel Distributors Corp.2008-11-07Not applicableUs
Gabapentintablet, film coated800 mg/1oralBlue Point Laboratories2013-07-24Not applicableUs
Gabapentincapsule600 mg/1oralRx Change Co.2014-11-09Not applicableUs
Gabapentintablet600 mg/1oralPreferred Pharmaceuticals, Inc.2006-04-01Not applicableUs
Gabapentincapsule300 mg/1oralMsm Repackaging2012-10-15Not applicableUs
Gabapentincapsule100 mg/1oralMc Kesson Contract Packaging2014-03-17Not applicableUs
Gabapentintablet800 mg/1oralMylan Pharmaceuticals Inc.2012-08-31Not applicableUs
Gabapentincapsule400 mg/1oralAphena Pharma Solutions Tennessee, Llc2008-01-31Not applicableUs
Gabapentincapsule400 mg/1oralActavis Pharma, Inc.2014-03-17Not applicableUs
Gabapentincapsule100 mg/1oralCardinal Health2005-04-06Not applicableUs
Gabapentintablet800 mg/1oralREMEDYREPACK INC.2011-09-23Not applicableUs
Gabapentincapsule100 mg/100mgoralWestminster Pharmaceuticals, Llc2016-04-01Not applicableUs
Gabapentincapsule100 mg/1oralLake Erie Medical DBA Quality Care Products LLC2011-11-05Not applicableUs
Gabapentinsolution250 mg/5mLoralTaro Pharmaceuticals U.S.A., Inc.2013-07-03Not applicableUs
Gabapentin KitkitPharmaceutica North America, Inc.2012-08-28Not applicableUs
Approved Over the Counter ProductsNot Available
Unapproved/Other Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
FanatrexkitoralCalifornia Pharmaceuticals Llc2010-05-15Not applicableUs
FanatrexkitoralCalifornia Pharmaceuticals, Llc2016-01-01Not applicableUs
International Brands
NameCompany
AcloniumNot Available
Novo-GabapentinNot Available
Brand mixtures
NameLabellerIngredients
Dipentocaine Topical Cream Compounding KitAlvix Laboratories, LLC
Gapeam BudibacAlvix Laboratories, LLC
Therapentin-60Physician Therapeutics Llc
Therapentin-90Physician Therapeutics Llc
SaltsNot Available
Categories
UNII6CW7F3G59X
CAS number60142-96-3
WeightAverage: 171.2368
Monoisotopic: 171.125928793
Chemical FormulaC9H17NO2
InChI KeyInChIKey=UGJMXCAKCUNAIE-UHFFFAOYSA-N
InChI
InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)
IUPAC Name
2-[1-(aminomethyl)cyclohexyl]acetic acid
SMILES
NCC1(CC(O)=O)CCCCC1
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as gamma amino acids and derivatives. These are amino acids having a (-NH2) group attached to the gamma carbon atom.
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
Sub ClassAmino acids, peptides, and analogues
Direct ParentGamma amino acids and derivatives
Alternative Parents
Substituents
  • Gamma amino acid or derivatives
  • Amino fatty acid
  • Fatty acyl
  • Monocarboxylic acid or derivatives
  • Carboxylic acid
  • Hydrocarbon derivative
  • Primary amine
  • Organooxygen compound
  • Organonitrogen compound
  • Primary aliphatic amine
  • Carbonyl group
  • Amine
  • Aliphatic homomonocyclic compound
Molecular FrameworkAliphatic homomonocyclic compounds
External Descriptors
Pharmacology
IndicationFor the management of postherpetic neuralgia in adults and as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in patients over 12 years of age with epilepsy.
PharmacodynamicsGabapentin, an analog of GABA, is used as an anticonvulsant to treat partial seizures, amyotrophic lateral sclerosis (ALS), and painful neuropathies. Potential uses include monotherapy of refractory partial seizure disorders, and treatment of spasticity in multiple sclerosis, tremor. mood disorders, and attenuation of disruptive behaviors in dementia. Gabapentin has high lipid solubility, is not metabolized by the liver, has no protein binding, and doesn't possess the usual drug interactions.
Mechanism of actionGabapentin interacts with cortical neurons at auxillary subunits of voltage-sensitive calcium channels. Gabapentin increases the synaptic concentration of GABA, enhances GABA responses at non-synaptic sites in neuronal tissues, and reduces the release of mono-amine neurotransmitters. One of the mechanisms implicated in this effect of gabapentin is the reduction of the axon excitability measured as an amplitude change of the presynaptic fibre volley (FV) in the CA1 area of the hippocampus. This is mediated through its binding to presynaptic NMDA receptors. Other studies have shown that the antihyperalgesic and antiallodynic effects of gabapentin are mediated by the descending noradrenergic system, resulting in the activation of spinal alpha2-adrenergic receptors. Gabapentin has also been shown to bind and activate the adenosine A1 receptor.
Related Articles
AbsorptionRapid. Absorbed in part by the L-amino acid transport system, which is a carrier-mediated, saturable transport system; as the dose increases, bioavailability decreases. Bioavailability ranges from approximately 60% for a 900 mg dose per day to approximately 27% for a 4800 milligram dose per day. Food has a slight effect on the rate and extent of absorption of gabapentin (14% increase in AUC).
Volume of distribution
  • 58±6 L
Protein bindingLess than 3% of gabapentin circulates bound to plasma protein.
Metabolism

All pharmacological actions following gabapentin administration are due to the activity of the parent compound; gabapentin is not appreciably metabolized in humans.

Route of eliminationGabapentin is eliminated from the systemic circulation by renal excretion as unchanged drug. Gabapentin is not appreciably metabolized in humans.
Half life5-7 hours
Clearance
  • 190 mL/min
ToxicitySymptoms of overdose include ataxia, labored breathing, ptosis, sedation, hypoactivity, and excitation.
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.941
Blood Brain Barrier+0.9382
Caco-2 permeable-0.7271
P-glycoprotein substrateNon-substrate0.6557
P-glycoprotein inhibitor INon-inhibitor0.9789
P-glycoprotein inhibitor IINon-inhibitor0.8866
Renal organic cation transporterNon-inhibitor0.7982
CYP450 2C9 substrateNon-substrate0.893
CYP450 2D6 substrateNon-substrate0.8124
CYP450 3A4 substrateNon-substrate0.7612
CYP450 1A2 substrateNon-inhibitor0.9409
CYP450 2C9 inhibitorNon-inhibitor0.9273
CYP450 2D6 inhibitorNon-inhibitor0.9418
CYP450 2C19 inhibitorNon-inhibitor0.9547
CYP450 3A4 inhibitorNon-inhibitor0.8438
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9706
Ames testNon AMES toxic0.9162
CarcinogenicityNon-carcinogens0.8536
BiodegradationNot ready biodegradable0.7046
Rat acute toxicity1.6472 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9406
hERG inhibition (predictor II)Non-inhibitor0.8659
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Actavis elizabeth llc
  • Amneal pharmaceuticals ny llc
  • Apotex inc etobicoke site
  • Aurobindo pharma usa inc
  • Hikma pharmaceuticals
  • Invagen pharmaceuticals inc
  • Ivax pharmaceuticals inc sub teva pharmaceuticals usa
  • Mutual pharmaceutical co inc
  • Ranbaxy laboratories ltd
  • Sandoz inc
  • Sun pharmaceutical industries ltd
  • Teva pharmaceuticals usa
  • Watson laboratories inc
  • Pfizer pharmaceuticals ltd
  • Parke davis div warner lambert co
  • Glenmark generics ltd
  • Matrix laboratories ltd
  • Teva pharmaceuticals usa inc
Packagers
Dosage forms
FormRouteStrength
Kittopical
Kitoral
Capsuleoral100 mg/100mg
Capsuleoral300 mg/300mg
Capsuleoral400 mg/400mg
Capsuleoral600 mg/1
Suspensionoral250 mg/5mL
Tabletoral600 1/1
Tabletoral600 mg/1
Tabletoral600 mg/600mg
Tabletoral800 mg/1
Tabletoral800 mg/800mg
Tablet, film coatedoral100 mg/1
Tablet, film coatedoral400 mg/1
Tablet, film coatedoral600 mg/1001
Tablet (immediate release)oral600 mg
Tablet (immediate release)oral800 mg
Tablet, film coatedoral300 mg/1
Kit
Capsuleoral100 mg/1
Capsuleoral300 mg/1
Capsuleoral400 mg/1
Solutionoral250 mg/5mL
Tablet, film coatedoral600 mg/1
Tablet, film coatedoral800 mg/1
Tabletoral600 mg
Tabletoral800 mg
Capsuleoral100 mg
Capsuleoral300 mg
Capsuleoral400 mg
Kit
Prices
Unit descriptionCostUnit
Gabapentin powder30.0USD g
Neurontin 800 mg tablet4.73USD tablet
Neurontin 600 mg tablet3.94USD tablet
Gabapentin 800 mg tablet3.09USD tablet
Gabapentin 600 mg tablet2.58USD tablet
Neurontin 400 mg Capsule1.97USD capsule
Neurontin 300 mg Capsule1.67USD capsule
Gabapentin 400 mg tablet1.59USD tablet
Gabapentin 300 mg tablet1.32USD tablet
Gabapentin 400 mg Capsule1.21USD capsule
Gabapentin 300 mg Capsule1.02USD capsule
Apo-Gabapentin 400 mg Capsule0.76USD capsule
Co Gabapentin 400 mg Capsule0.76USD capsule
Mylan-Gabapentin 400 mg Capsule0.76USD capsule
Novo-Gabapentin 400 mg Capsule0.76USD capsule
Phl-Gabapentin 400 mg Capsule0.76USD capsule
Pms-Gabapentin 400 mg Capsule0.76USD capsule
Ran-Gabapentin 400 mg Capsule0.76USD capsule
Ratio-Gabapentin 400 mg Capsule0.76USD capsule
Neurontin 100 mg Capsule0.65USD capsule
Apo-Gabapentin 300 mg Capsule0.64USD capsule
Co Gabapentin 300 mg Capsule0.64USD capsule
Mylan-Gabapentin 300 mg Capsule0.64USD capsule
Novo-Gabapentin 300 mg Capsule0.64USD capsule
Phl-Gabapentin 300 mg Capsule0.64USD capsule
Pms-Gabapentin 300 mg Capsule0.64USD capsule
Ran-Gabapentin 300 mg Capsule0.64USD capsule
Ratio-Gabapentin 300 mg Capsule0.64USD capsule
Gabapentin 100 mg tablet0.53USD tablet
Gabapentin 100 mg Capsule0.41USD capsule
Neurontin 250 mg/5ml Solution0.32USD ml
Apo-Gabapentin 100 mg Capsule0.26USD capsule
Co Gabapentin 100 mg Capsule0.26USD capsule
Mylan-Gabapentin 100 mg Capsule0.26USD capsule
Novo-Gabapentin 100 mg Capsule0.26USD capsule
Phl-Gabapentin 100 mg Capsule0.26USD capsule
Pms-Gabapentin 100 mg Capsule0.26USD capsule
Ran-Gabapentin 100 mg Capsule0.26USD capsule
Ratio-Gabapentin 100 mg Capsule0.26USD capsule
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
CA2215923 No2001-10-092016-04-26Canada
CA2327285 No2005-06-142019-05-10Canada
US6054482 Yes1997-10-252017-10-25Us
US6340475 No1996-09-192016-09-19Us
US6488962 No2000-06-202020-06-20Us
US6635280 No1996-09-192016-09-19Us
US6723340 No2001-10-252021-10-25Us
US7256216 Yes2002-11-282022-11-28Us
US7438927 No2004-02-262024-02-26Us
US7731989 No2002-10-252022-10-25Us
US8192756 No2002-10-252022-10-25Us
US8252332 No2002-10-252022-10-25Us
US8333992 No2002-10-252022-10-25Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point162-166 °CNot Available
water solubility4490 mg/LNot Available
logP-1.10SANGSTER (1994)
Predicted Properties
PropertyValueSource
Water Solubility4.34 mg/mLALOGPS
logP-1.9ALOGPS
logP-1.3ChemAxon
logS-1.6ALOGPS
pKa (Strongest Acidic)4.63ChemAxon
pKa (Strongest Basic)9.91ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area63.32 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity46.33 m3·mol-1ChemAxon
Polarizability18.92 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, NegativeNot Available
1D NMR1H NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
References
Synthesis Reference

Donald E. Butler, Barbara J. Greenman, “Gabapentin mohohydrate and a process for producing the same.” U.S. Patent US4960931, issued May, 1978.

US4960931
General References
  1. Mathew NT, Rapoport A, Saper J, Magnus L, Klapper J, Ramadan N, Stacey B, Tepper S: Efficacy of gabapentin in migraine prophylaxis. Headache. 2001 Feb;41(2):119-28. [PubMed:11251695 ]
  2. Backonja MM, Serra J: Pharmacologic management part 1: better-studied neuropathic pain diseases. Pain Med. 2004 Mar;5 Suppl 1:S28-47. [PubMed:14996228 ]
  3. Choudhuri I, Sarvananthan N, Gottlob I: Survey of management of acquired nystagmus in the United Kingdom. Eye (Lond). 2007 Sep;21(9):1194-7. Epub 2006 May 26. [PubMed:16732211 ]
  4. Pande AC, Crockatt JG, Janney CA, Werth JL, Tsaroucha G: Gabapentin in bipolar disorder: a placebo-controlled trial of adjunctive therapy. Gabapentin Bipolar Disorder Study Group. Bipolar Disord. 2000 Sep;2(3 Pt 2):249-55. [PubMed:11249802 ]
  5. Su TZ, Feng MR, Weber ML: Mediation of highly concentrative uptake of pregabalin by L-type amino acid transport in Chinese hamster ovary and Caco-2 cells. J Pharmacol Exp Ther. 2005 Jun;313(3):1406-15. Epub 2005 Mar 15. [PubMed:15769862 ]
External Links
ATC CodesN03AX12
AHFS Codes
  • 28:12.92
PDB EntriesNot Available
FDA labelDownload (1.5 MB)
MSDSDownload (73.3 KB)
Interactions
Drug Interactions
Drug
2-HYDROXY-1,4-NAPHTHOQUINONEThe risk or severity of adverse effects can be increased when 2-HYDROXY-1,4-NAPHTHOQUINONE is combined with Gabapentin.
2-mercaptobenzothiazoleThe risk or severity of adverse effects can be increased when 2-mercaptobenzothiazole is combined with Gabapentin.
7-NitroindazoleThe risk or severity of adverse effects can be increased when Gabapentin is combined with 7-Nitroindazole.
AcepromazineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Acepromazine.
AceprometazineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Aceprometazine.
adipiplonThe risk or severity of adverse effects can be increased when Gabapentin is combined with adipiplon.
AgomelatineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Agomelatine.
AlfaxaloneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Alfaxalone.
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Gabapentin.
AlfuzosinAlfuzosin may increase the hypotensive activities of Gabapentin.
AlphacetylmethadolThe risk or severity of adverse effects can be increased when Gabapentin is combined with Alphacetylmethadol.
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Gabapentin.
Aluminum hydroxideThe serum concentration of Gabapentin can be decreased when it is combined with Aluminum hydroxide.
Aluminum phosphateThe serum concentration of Gabapentin can be decreased when it is combined with Aluminum phosphate.
AmisulprideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Amisulpride.
AmitriptylineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Amitriptyline.
AmobarbitalThe metabolism of Gabapentin can be increased when combined with Amobarbital.
AmobarbitalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Amobarbital.
AmorolfineThe risk or severity of adverse effects can be increased when Amorolfine is combined with Gabapentin.
AmoxapineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Amoxapine.
AmperozideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Amperozide.
Amphotericin BThe risk or severity of adverse effects can be increased when Amphotericin B is combined with Gabapentin.
AN2690The risk or severity of adverse effects can be increased when AN2690 is combined with Gabapentin.
AnidulafunginThe risk or severity of adverse effects can be increased when Anidulafungin is combined with Gabapentin.
AripiprazoleThe risk or severity of adverse effects can be increased when Gabapentin is combined with Aripiprazole.
ArtemetherThe risk or severity of adverse effects can be increased when Artemether is combined with Gabapentin.
ArticaineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Articaine.
AsenapineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Asenapine.
AtosibanThe risk or severity of adverse effects can be increased when Gabapentin is combined with Atosiban.
Atracurium besylateGabapentin may increase the neuromuscular blocking activities of Atracurium besylate.
AzaperoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Azaperone.
AzelastineGabapentin may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
AzelastineThe risk or severity of adverse effects can be increased when Azelastine is combined with Gabapentin.
BaclofenThe risk or severity of adverse effects can be increased when Gabapentin is combined with Baclofen.
Bafilomycin A1The risk or severity of adverse effects can be increased when Bafilomycin A1 is combined with Gabapentin.
BarbitalThe metabolism of Gabapentin can be increased when combined with Barbital.
BarbitalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Barbital.
BenzocaineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Benzocaine.
Benzoic AcidThe risk or severity of adverse effects can be increased when Benzoic Acid is combined with Gabapentin.
Benzyl alcoholThe risk or severity of adverse effects can be increased when Gabapentin is combined with Benzyl alcohol.
BifonazoleThe risk or severity of adverse effects can be increased when Bifonazole is combined with Gabapentin.
Bismuth SubcitrateThe serum concentration of Gabapentin can be decreased when it is combined with Bismuth Subcitrate.
BrexpiprazoleThe risk or severity of adverse effects can be increased when Gabapentin is combined with Brexpiprazole.
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
BrimonidineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Brimonidine.
BromazepamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Bromazepam.
BrompheniramineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Brompheniramine.
BrotizolamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Brotizolam.
BupivacaineThe risk or severity of adverse effects can be increased when Bupivacaine is combined with Gabapentin.
BuprenorphineThe risk or severity of adverse effects can be increased when Buprenorphine is combined with Gabapentin.
BuspironeThe risk or severity of adverse effects can be increased when Buspirone is combined with Gabapentin.
ButabarbitalThe risk or severity of adverse effects can be increased when Butabarbital is combined with Gabapentin.
ButacaineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Butacaine.
ButalbitalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Butalbital.
ButambenThe risk or severity of adverse effects can be increased when Gabapentin is combined with Butamben.
ButenafineThe risk or severity of adverse effects can be increased when Butenafine is combined with Gabapentin.
ButethalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Butethal.
ButoconazoleThe risk or severity of adverse effects can be increased when Butoconazole is combined with Gabapentin.
ButorphanolThe risk or severity of adverse effects can be increased when Butorphanol is combined with Gabapentin.
Calcium carbonateThe serum concentration of Gabapentin can be decreased when it is combined with Calcium carbonate.
CandicidinThe risk or severity of adverse effects can be increased when Candicidin is combined with Gabapentin.
CarbamazepineThe risk or severity of adverse effects can be increased when Carbamazepine is combined with Gabapentin.
CarbinoxamineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Carbinoxamine.
CarfentanilThe risk or severity of adverse effects can be increased when Gabapentin is combined with Carfentanil.
CarisoprodolThe risk or severity of adverse effects can be increased when Gabapentin is combined with Carisoprodol.
CarvedilolCarvedilol may increase the hypotensive activities of Gabapentin.
CaspofunginThe risk or severity of adverse effects can be increased when Caspofungin is combined with Gabapentin.
CeruleninThe risk or severity of adverse effects can be increased when Cerulenin is combined with Gabapentin.
CetirizineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Cetirizine.
Chloral hydrateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Chloral hydrate.
ChlordiazepoxideThe risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Gabapentin.
ChlormezanoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Chlormezanone.
ChloroprocaineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Chloroprocaine.
ChloroxineThe risk or severity of adverse effects can be increased when Chloroxine is combined with Gabapentin.
ChlorphenamineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Chlorphenamine.
ChlorpromazineThe risk or severity of adverse effects can be increased when Chlorpromazine is combined with Gabapentin.
ChlorprothixeneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Chlorprothixene.
ChlorzoxazoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Chlorzoxazone.
CiclopiroxThe risk or severity of adverse effects can be increased when Ciclopirox is combined with Gabapentin.
CimetidineThe serum concentration of Gabapentin can be increased when it is combined with Cimetidine.
CinchocaineThe risk or severity of adverse effects can be increased when Cinchocaine is combined with Gabapentin.
CitalopramThe risk or severity of adverse effects can be increased when Gabapentin is combined with Citalopram.
ClemastineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Clemastine.
ClidiniumThe risk or severity of adverse effects can be increased when Gabapentin is combined with Clidinium.
ClobazamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Clobazam.
clomethiazoleThe risk or severity of adverse effects can be increased when Gabapentin is combined with clomethiazole.
ClomipramineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Clomipramine.
ClonazepamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Clonazepam.
ClonidineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Clonidine.
ClopidogrelThe therapeutic efficacy of Clopidogrel can be decreased when used in combination with Gabapentin.
ClorazepateThe risk or severity of adverse effects can be increased when Clorazepate is combined with Gabapentin.
ClotrimazoleThe risk or severity of adverse effects can be increased when Clotrimazole is combined with Gabapentin.
ClozapineThe risk or severity of adverse effects can be increased when Clozapine is combined with Gabapentin.
CocaineThe risk or severity of adverse effects can be increased when Cocaine is combined with Gabapentin.
CodeineThe risk or severity of adverse effects can be increased when Codeine is combined with Gabapentin.
CyclizineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Cyclizine.
CyclobenzaprineThe risk or severity of adverse effects can be increased when Cyclobenzaprine is combined with Gabapentin.
CyclosporineThe risk or severity of adverse effects can be increased when Cyclosporine is combined with Gabapentin.
CyproheptadineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Cyproheptadine.
DantroleneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Dantrolene.
DapiprazoleThe risk or severity of adverse effects can be increased when Dapiprazole is combined with Gabapentin.
DapoxetineDapoxetine may increase the orthostatic hypotensive activities of Gabapentin.
DapoxetineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Dapoxetine.
Decanoic AcidThe risk or severity of adverse effects can be increased when Decanoic Acid is combined with Gabapentin.
deramciclaneThe risk or severity of adverse effects can be increased when Gabapentin is combined with deramciclane.
DesfluraneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Desflurane.
DesipramineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Desipramine.
DesloratadineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Desloratadine.
DetomidineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Detomidine.
DexbrompheniramineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Dexbrompheniramine.
DexmedetomidineThe risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Gabapentin.
DextromoramideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Dextromoramide.
DextropropoxypheneThe risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Gabapentin.
DezocineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Dezocine.
DiazepamThe risk or severity of adverse effects can be increased when Diazepam is combined with Gabapentin.
DifenoxinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Difenoxin.
DihydrocodeineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Dihydrocodeine.
DihydroetorphineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Dihydroetorphine.
DihydromorphineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Dihydromorphine.
DimenhydrinateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Dimenhydrinate.
DiphenhydramineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Diphenhydramine.
DiphenoxylateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Diphenoxylate.
DoramectinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Doramectin.
DoxazosinDoxazosin may increase the hypotensive activities of Gabapentin.
DoxepinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Doxepin.
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
DoxylamineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Doxylamine.
DPDPEThe risk or severity of adverse effects can be increased when Gabapentin is combined with DPDPE.
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
DroperidolThe risk or severity of adverse effects can be increased when Droperidol is combined with Gabapentin.
DrotebanolThe risk or severity of adverse effects can be increased when Gabapentin is combined with Drotebanol.
DyclonineThe risk or severity of adverse effects can be increased when Dyclonine is combined with Gabapentin.
EcgonineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ecgonine.
ECGONINE METHYL ESTERThe risk or severity of adverse effects can be increased when Gabapentin is combined with ECGONINE METHYL ESTER.
EconazoleThe risk or severity of adverse effects can be increased when Econazole is combined with Gabapentin.
EfavirenzThe serum concentration of Gabapentin can be decreased when it is combined with Efavirenz.
EfavirenzThe risk or severity of adverse effects can be increased when Gabapentin is combined with Efavirenz.
EfinaconazoleThe risk or severity of adverse effects can be increased when Efinaconazole is combined with Gabapentin.
EnfluraneThe risk or severity of adverse effects can be increased when Enflurane is combined with Gabapentin.
EntacaponeThe risk or severity of adverse effects can be increased when Gabapentin is combined with Entacapone.
EscitalopramThe risk or severity of adverse effects can be increased when Gabapentin is combined with Escitalopram.
EstazolamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Estazolam.
EszopicloneThe risk or severity of adverse effects can be increased when Eszopiclone is combined with Gabapentin.
EthanolGabapentin may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
EthanolThe risk or severity of adverse effects can be increased when Ethanol is combined with Gabapentin.
EthchlorvynolThe risk or severity of adverse effects can be increased when Ethchlorvynol is combined with Gabapentin.
EthosuximideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ethosuximide.
EthotoinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ethotoin.
Ethyl carbamateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ethyl carbamate.
Ethyl loflazepateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ethyl loflazepate.
EthylmorphineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ethylmorphine.
EtidocaineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Etidocaine.
EtifoxineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Etifoxine.
EtizolamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Etizolam.
EtomidateThe risk or severity of adverse effects can be increased when Etomidate is combined with Gabapentin.
EtoperidoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Etoperidone.
EtorphineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Etorphine.
EzogabineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ezogabine.
FelbamateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Felbamate.
FencamfamineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Fencamfamine.
FenfluramineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Fenfluramine.
FentanylThe risk or severity of adverse effects can be increased when Fentanyl is combined with Gabapentin.
FexofenadineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Fexofenadine.
FlibanserinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Flibanserin.
FluconazoleThe serum concentration of Gabapentin can be increased when it is combined with Fluconazole.
FlucytosineThe risk or severity of adverse effects can be increased when Flucytosine is combined with Gabapentin.
FludiazepamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Fludiazepam.
FlunarizineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Flunarizine.
FlunitrazepamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Flunitrazepam.
FluoxetineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Fluoxetine.
FlupentixolThe risk or severity of adverse effects can be increased when Flupentixol is combined with Gabapentin.
FluphenazineThe risk or severity of adverse effects can be increased when Fluphenazine is combined with Gabapentin.
FlurazepamThe risk or severity of adverse effects can be increased when Flurazepam is combined with Gabapentin.
FluspirileneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Fluspirilene.
Fluticasone PropionateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Fluticasone Propionate.
FluvoxamineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Fluvoxamine.
FosphenytoinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Fosphenytoin.
FospropofolThe risk or severity of adverse effects can be increased when Gabapentin is combined with Fospropofol.
gabapentin enacarbilThe risk or severity of adverse effects can be increased when Gabapentin is combined with gabapentin enacarbil.
Gamma Hydroxybutyric AcidThe risk or severity of adverse effects can be increased when Gabapentin is combined with Gamma Hydroxybutyric Acid.
GlutethimideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Glutethimide.
GlyphosateThe risk or severity of adverse effects can be increased when Glyphosate is combined with Gabapentin.
GriseofulvinThe risk or severity of adverse effects can be increased when Griseofulvin is combined with Gabapentin.
GuanfacineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Guanfacine.
HalazepamThe risk or severity of adverse effects can be increased when Halazepam is combined with Gabapentin.
HaloperidolThe risk or severity of adverse effects can be increased when Haloperidol is combined with Gabapentin.
HaloproginThe risk or severity of adverse effects can be increased when Haloprogin is combined with Gabapentin.
HalothaneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Halothane.
HeroinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Heroin.
HexetidineThe risk or severity of adverse effects can be increased when Hexetidine is combined with Gabapentin.
HexobarbitalThe metabolism of Gabapentin can be increased when combined with Hexobarbital.
HexobarbitalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Hexobarbital.
HydrocodoneThe risk or severity of adverse effects can be increased when Hydrocodone is combined with Gabapentin.
HydromorphoneThe risk or severity of adverse effects can be increased when Hydromorphone is combined with Gabapentin.
HydroxyzineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
HydroxyzineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Hydroxyzine.
IloperidoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Iloperidone.
ImipramineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Imipramine.
IndalpineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Indalpine.
IndoraminIndoramin may increase the hypotensive activities of Gabapentin.
IsoconazoleThe risk or severity of adverse effects can be increased when Isoconazole is combined with Gabapentin.
IsofluraneThe risk or severity of adverse effects can be increased when Isoflurane is combined with Gabapentin.
ItraconazoleThe risk or severity of adverse effects can be increased when Itraconazole is combined with Gabapentin.
KetamineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ketamine.
KetazolamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ketazolam.
KetobemidoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ketobemidone.
KetoconazoleThe risk or severity of adverse effects can be increased when Ketoconazole is combined with Gabapentin.
LabetalolLabetalol may increase the hypotensive activities of Gabapentin.
LamotrigineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Lamotrigine.
LevetiracetamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Levetiracetam.
LevobupivacaineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Levobupivacaine.
LevocabastineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Levocabastine.
LevocetirizineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Levocetirizine.
LevodopaThe risk or severity of adverse effects can be increased when Gabapentin is combined with Levodopa.
Levomethadyl AcetateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Levomethadyl Acetate.
LevomilnacipranThe risk or severity of adverse effects can be increased when Gabapentin is combined with Levomilnacipran.
LevorphanolThe risk or severity of adverse effects can be increased when Levorphanol is combined with Gabapentin.
LidocaineThe risk or severity of adverse effects can be increased when Lidocaine is combined with Gabapentin.
LithiumThe risk or severity of adverse effects can be increased when Gabapentin is combined with Lithium.
LofentanilThe risk or severity of adverse effects can be increased when Gabapentin is combined with Lofentanil.
LoratadineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Loratadine.
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Gabapentin.
LoxapineThe risk or severity of adverse effects can be increased when Loxapine is combined with Gabapentin.
Lu AA21004The risk or severity of adverse effects can be increased when Gabapentin is combined with Lu AA21004.
LurasidoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Lurasidone.
MagaldrateThe serum concentration of Gabapentin can be decreased when it is combined with Magaldrate.
Magnesium carbonateThe serum concentration of Gabapentin can be decreased when it is combined with Magnesium carbonate.
Magnesium hydroxideMagnesium hydroxide may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
Magnesium hydroxideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Magnesium hydroxide.
Magnesium oxideMagnesium oxide may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
Magnesium oxideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Magnesium oxide.
Magnesium salicylateMagnesium salicylate may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
Magnesium salicylateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Magnesium salicylate.
Magnesium SulfateMagnesium Sulfate may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
Magnesium SulfateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Magnesium Sulfate.
Magnesium TrisilicateThe serum concentration of Gabapentin can be decreased when it is combined with Magnesium Trisilicate.
MaprotilineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Maprotiline.
MeclizineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Meclizine.
MedetomidineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Medetomidine.
MefloquineThe therapeutic efficacy of Gabapentin can be decreased when used in combination with Mefloquine.
MelatoninThe risk or severity of adverse effects can be increased when Gabapentin is combined with Melatonin.
MelperoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Melperone.
MepivacaineThe risk or severity of adverse effects can be increased when Mepivacaine is combined with Gabapentin.
MeprobamateThe risk or severity of adverse effects can be increased when Meprobamate is combined with Gabapentin.
MesoridazineThe risk or severity of adverse effects can be increased when Mesoridazine is combined with Gabapentin.
MetaxaloneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Metaxalone.
MethadoneThe risk or severity of adverse effects can be increased when Methadone is combined with Gabapentin.
Methadyl AcetateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Methadyl Acetate.
MethapyrileneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Methapyrilene.
MethaqualoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Methaqualone.
MethocarbamolThe risk or severity of adverse effects can be increased when Gabapentin is combined with Methocarbamol.
MethohexitalThe metabolism of Gabapentin can be increased when combined with Methohexital.
MethohexitalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Methohexital.
MethotrimeprazineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Methotrimeprazine.
MethoxyfluraneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Methoxyflurane.
MethsuximideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Methsuximide.
MethylphenobarbitalThe metabolism of Gabapentin can be increased when combined with Methylphenobarbital.
MethylphenobarbitalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Methylphenobarbital.
MetyrosineGabapentin may increase the sedative activities of Metyrosine.
MevastatinThe risk or severity of adverse effects can be increased when Mevastatin is combined with Gabapentin.
MianserinThe therapeutic efficacy of Gabapentin can be decreased when used in combination with Mianserin.
MicafunginThe risk or severity of adverse effects can be increased when Micafungin is combined with Gabapentin.
MiconazoleThe risk or severity of adverse effects can be increased when Miconazole is combined with Gabapentin.
MidazolamThe risk or severity of adverse effects can be increased when Midazolam is combined with Gabapentin.
MilnacipranThe risk or severity of adverse effects can be increased when Gabapentin is combined with Milnacipran.
MiltefosineThe risk or severity of adverse effects can be increased when Miltefosine is combined with Gabapentin.
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
MirtazapineGabapentin may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
MirtazapineThe risk or severity of adverse effects can be increased when Mirtazapine is combined with Gabapentin.
MivacuriumGabapentin may increase the neuromuscular blocking activities of Mivacurium.
MolindoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Molindone.
MonensinThe risk or severity of adverse effects can be increased when Monensin is combined with Gabapentin.
MorphineThe risk or severity of adverse effects can be increased when Morphine is combined with Gabapentin.
MyxothiazolThe risk or severity of adverse effects can be increased when Myxothiazol is combined with Gabapentin.
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Gabapentin.
NabiloneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Nabilone.
NafcillinThe metabolism of Gabapentin can be increased when combined with Nafcillin.
NaftifineThe risk or severity of adverse effects can be increased when Naftifine is combined with Gabapentin.
NalbuphineThe risk or severity of adverse effects can be increased when Nalbuphine is combined with Gabapentin.
NatamycinThe risk or severity of adverse effects can be increased when Natamycin is combined with Gabapentin.
NitrazepamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Nitrazepam.
NitroprussideGabapentin may increase the hypotensive activities of Nitroprusside.
Nitrous oxideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Nitrous oxide.
NitroxolineThe risk or severity of adverse effects can be increased when Nitroxoline is combined with Gabapentin.
NormethadoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Normethadone.
NortriptylineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Nortriptyline.
NystatinThe risk or severity of adverse effects can be increased when Nystatin is combined with Gabapentin.
OlanzapineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Olanzapine.
OlopatadineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Olopatadine.
OndansetronThe risk or severity of adverse effects can be increased when Ondansetron is combined with Gabapentin.
OpiumThe risk or severity of adverse effects can be increased when Gabapentin is combined with Opium.
OrlistatThe serum concentration of Gabapentin can be decreased when it is combined with Orlistat.
OrphenadrineGabapentin may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
OrphenadrineThe risk or severity of adverse effects can be increased when Orphenadrine is combined with Gabapentin.
OsanetantThe risk or severity of adverse effects can be increased when Gabapentin is combined with Osanetant.
OxazepamThe risk or severity of adverse effects can be increased when Oxazepam is combined with Gabapentin.
OxiconazoleThe risk or severity of adverse effects can be increased when Oxiconazole is combined with Gabapentin.
OxprenololThe risk or severity of adverse effects can be increased when Gabapentin is combined with Oxprenolol.
OxybuprocaineThe risk or severity of adverse effects can be increased when Oxybuprocaine is combined with Gabapentin.
OxycodoneThe risk or severity of adverse effects can be increased when Oxycodone is combined with Gabapentin.
OxymorphoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Oxymorphone.
pafuramidineThe risk or severity of adverse effects can be increased when pafuramidine is combined with Gabapentin.
PaliperidoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Paliperidone.
ParaldehydeGabapentin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ParaldehydeThe risk or severity of adverse effects can be increased when Paraldehyde is combined with Gabapentin.
ParoxetineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Paroxetine.
PentamidineThe risk or severity of adverse effects can be increased when Pentamidine is combined with Gabapentin.
PentazocineThe risk or severity of adverse effects can be increased when Pentazocine is combined with Gabapentin.
PentobarbitalThe metabolism of Gabapentin can be increased when combined with Pentobarbital.
PentobarbitalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Pentobarbital.
PerampanelThe risk or severity of adverse effects can be increased when Gabapentin is combined with Perampanel.
PerospironeThe risk or severity of adverse effects can be increased when Gabapentin is combined with Perospirone.
PerphenazineThe risk or severity of adverse effects can be increased when Perphenazine is combined with Gabapentin.
PethidineThe risk or severity of adverse effects can be increased when Pethidine is combined with Gabapentin.
PhenobarbitalThe metabolism of Gabapentin can be increased when combined with Phenobarbital.
PhenobarbitalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Phenobarbital.
PhenoxyethanolThe risk or severity of adverse effects can be increased when Gabapentin is combined with Phenoxyethanol.
PhenytoinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Phenytoin.
PimozideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Pimozide.
PipamperoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Pipamperone.
PipotiazineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Pipotiazine.
PizotifenThe risk or severity of adverse effects can be increased when Gabapentin is combined with Pizotifen.
PomalidomideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Pomalidomide.
PosaconazoleThe risk or severity of adverse effects can be increased when Posaconazole is combined with Gabapentin.
PramipexoleGabapentin may increase the sedative activities of Pramipexole.
PramocaineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Pramocaine.
PrazepamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Prazepam.
PrazosinPrazosin may increase the hypotensive activities of Gabapentin.
PregabalinThe risk or severity of adverse effects can be increased when Pregabalin is combined with Gabapentin.
PrilocaineThe risk or severity of adverse effects can be increased when Prilocaine is combined with Gabapentin.
PrimidoneThe metabolism of Gabapentin can be increased when combined with Primidone.
PrimidoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Primidone.
ProcaineThe risk or severity of adverse effects can be increased when Procaine is combined with Gabapentin.
ProchlorperazineThe risk or severity of adverse effects can be increased when Prochlorperazine is combined with Gabapentin.
PromazineThe risk or severity of adverse effects can be increased when Promazine is combined with Gabapentin.
PromethazineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Promethazine.
ProparacaineThe risk or severity of adverse effects can be increased when Proparacaine is combined with Gabapentin.
PropofolThe risk or severity of adverse effects can be increased when Propofol is combined with Gabapentin.
PropoxycaineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Propoxycaine.
ProtriptylineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Protriptyline.
PSD502The risk or severity of adverse effects can be increased when Gabapentin is combined with PSD502.
QuazepamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Quazepam.
QuetiapineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Quetiapine.
RadicicolThe risk or severity of adverse effects can be increased when Radicicol is combined with Gabapentin.
RamelteonThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ramelteon.
RapacuroniumGabapentin may increase the neuromuscular blocking activities of Rapacuronium.
RemifentanilThe risk or severity of adverse effects can be increased when Remifentanil is combined with Gabapentin.
RemoxiprideThe risk or severity of adverse effects can be increased when Remoxipride is combined with Gabapentin.
ReserpineThe risk or severity of adverse effects can be increased when Reserpine is combined with Gabapentin.
RisperidoneThe risk or severity of adverse effects can be increased when Risperidone is combined with Gabapentin.
RomifidineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Romifidine.
RopiniroleGabapentin may increase the sedative activities of Ropinirole.
RopivacaineThe risk or severity of adverse effects can be increased when Ropivacaine is combined with Gabapentin.
RotigotineGabapentin may increase the sedative activities of Rotigotine.
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Gabapentin.
S-EthylisothioureaThe risk or severity of adverse effects can be increased when Gabapentin is combined with S-Ethylisothiourea.
Salicylhydroxamic AcidThe risk or severity of adverse effects can be increased when Salicylhydroxamic Acid is combined with Gabapentin.
Salicylic acidThe risk or severity of adverse effects can be increased when Salicylic acid is combined with Gabapentin.
ScopolamineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Scopolamine.
SecobarbitalThe metabolism of Gabapentin can be increased when combined with Secobarbital.
SecobarbitalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Secobarbital.
SertaconazoleThe risk or severity of adverse effects can be increased when Sertaconazole is combined with Gabapentin.
SertindoleThe risk or severity of adverse effects can be increased when Gabapentin is combined with Sertindole.
SertralineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Sertraline.
SevofluraneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Sevoflurane.
SilodosinSilodosin may increase the hypotensive activities of Gabapentin.
SinefunginThe risk or severity of adverse effects can be increased when Sinefungin is combined with Gabapentin.
SirolimusThe risk or severity of adverse effects can be increased when Sirolimus is combined with Gabapentin.
Sodium oxybateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Sodium oxybate.
StiripentolThe risk or severity of adverse effects can be increased when Gabapentin is combined with Stiripentol.
SufentanilThe risk or severity of adverse effects can be increased when Sufentanil is combined with Gabapentin.
SulconazoleThe risk or severity of adverse effects can be increased when Sulconazole is combined with Gabapentin.
SulpirideThe risk or severity of adverse effects can be increased when Sulpiride is combined with Gabapentin.
SuvorexantThe risk or severity of adverse effects can be increased when Gabapentin is combined with Suvorexant.
TamsulosinTamsulosin may increase the hypotensive activities of Gabapentin.
TapentadolThe risk or severity of adverse effects can be increased when Gabapentin is combined with Tapentadol.
TasimelteonThe risk or severity of adverse effects can be increased when Gabapentin is combined with Tasimelteon.
TavaboroleThe risk or severity of adverse effects can be increased when Tavaborole is combined with Gabapentin.
TemazepamThe risk or severity of adverse effects can be increased when Temazepam is combined with Gabapentin.
TerazosinTerazosin may increase the hypotensive activities of Gabapentin.
TerbinafineThe risk or severity of adverse effects can be increased when Terbinafine is combined with Gabapentin.
TerconazoleThe risk or severity of adverse effects can be increased when Terconazole is combined with Gabapentin.
TetrabenazineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Tetrabenazine.
TetracaineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Tetracaine.
TetrodotoxinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Tetrodotoxin.
ThalidomideGabapentin may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
ThalidomideThe risk or severity of adverse effects can be increased when Thalidomide is combined with Gabapentin.
ThiamylalThe metabolism of Gabapentin can be increased when combined with Thiamylal.
ThiamylalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Thiamylal.
ThiopentalThe metabolism of Gabapentin can be increased when combined with Thiopental.
ThiopentalThe risk or severity of adverse effects can be increased when Gabapentin is combined with Thiopental.
ThioridazineThe risk or severity of adverse effects can be increased when Thioridazine is combined with Gabapentin.
ThiothixeneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Thiothixene.
ThymolThe risk or severity of adverse effects can be increased when Thymol is combined with Gabapentin.
TiagabineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Tiagabine.
TiletamineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Tiletamine.
TioconazoleThe risk or severity of adverse effects can be increased when Tioconazole is combined with Gabapentin.
TizanidineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Tizanidine.
TolcaponeThe risk or severity of adverse effects can be increased when Gabapentin is combined with Tolcapone.
TolnaftateThe risk or severity of adverse effects can be increased when Tolnaftate is combined with Gabapentin.
TopiramateThe risk or severity of adverse effects can be increased when Gabapentin is combined with Topiramate.
TramadolThe risk or severity of adverse effects can be increased when Tramadol is combined with Gabapentin.
Trans-2-PhenylcyclopropylamineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Trans-2-Phenylcyclopropylamine.
TranylcypromineThe risk or severity of adverse effects can be increased when Tranylcypromine is combined with Gabapentin.
TrazodoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Trazodone.
TriazolamThe risk or severity of adverse effects can be increased when Triazolam is combined with Gabapentin.
TrifluoperazineThe risk or severity of adverse effects can be increased when Trifluoperazine is combined with Gabapentin.
TriflupromazineThe risk or severity of adverse effects can be increased when Triflupromazine is combined with Gabapentin.
TrimazosinTrimazosin may increase the hypotensive activities of Gabapentin.
TrimetrexateThe risk or severity of adverse effects can be increased when Trimetrexate is combined with Gabapentin.
TrimipramineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Trimipramine.
TriprolidineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Triprolidine.
Valproic AcidThe risk or severity of adverse effects can be increased when Valproic Acid is combined with Gabapentin.
VigabatrinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Vigabatrin.
VilazodoneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Vilazodone.
VoriconazoleThe risk or severity of adverse effects can be increased when Voriconazole is combined with Gabapentin.
VortioxetineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Vortioxetine.
XylazineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Xylazine.
YohimbineThe therapeutic efficacy of Gabapentin can be decreased when used in combination with Yohimbine.
ZaleplonThe risk or severity of adverse effects can be increased when Zaleplon is combined with Gabapentin.
ZiconotideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Ziconotide.
ZimelidineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Zimelidine.
ZiprasidoneThe risk or severity of adverse effects can be increased when Ziprasidone is combined with Gabapentin.
ZolazepamThe risk or severity of adverse effects can be increased when Gabapentin is combined with Zolazepam.
ZolpidemThe risk or severity of adverse effects can be increased when Zolpidem is combined with Gabapentin.
ZonisamideThe risk or severity of adverse effects can be increased when Gabapentin is combined with Zonisamide.
ZopicloneThe risk or severity of adverse effects can be increased when Gabapentin is combined with Zopiclone.
ZotepineThe risk or severity of adverse effects can be increased when Gabapentin is combined with Zotepine.
ZuclopenthixolThe risk or severity of adverse effects can be increased when Gabapentin is combined with Zuclopenthixol.
Food Interactions
  • Avoid alcohol.
  • Take without regard to meals.

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Voltage-gated calcium channel activity
Specific Function:
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling (By similarity).
Gene Name:
CACNA2D1
Uniprot ID:
P54289
Molecular Weight:
124566.93 Da
References
  1. Maneuf YP, Luo ZD, Lee K: alpha2delta and the mechanism of action of gabapentin in the treatment of pain. Semin Cell Dev Biol. 2006 Oct;17(5):565-70. Epub 2006 Sep 24. [PubMed:17067834 ]
  2. Hota D, Bansal V, Pattanaik S: Evaluation of ketamine, nimodipine, gabapentin and imipramine in partial sciatic nerve transection model of neuropathic pain in rat: an experimental study. Methods Find Exp Clin Pharmacol. 2007 Sep;29(7):443-6. [PubMed:17982508 ]
  3. Gazulla J, Tintore MA: The P/Q-type voltage-dependent calcium channel as pharmacological target in spinocerebellar ataxia type 6: gabapentin and pregabalin may be of therapeutic benefit. Med Hypotheses. 2007;68(1):131-6. Epub 2006 Aug 8. [PubMed:16899342 ]
  4. Hendrich J, Van Minh AT, Heblich F, Nieto-Rostro M, Watschinger K, Striessnig J, Wratten J, Davies A, Dolphin AC: Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3628-33. doi: 10.1073/pnas.0708930105. Epub 2008 Feb 25. [PubMed:18299583 ]
  5. Hoffmann U, Dilekoz E, Kudo C, Ayata C: Gabapentin suppresses cortical spreading depression susceptibility. J Cereb Blood Flow Metab. 2010 Sep;30(9):1588-92. doi: 10.1038/jcbfm.2010.92. Epub 2010 Jun 30. [PubMed:20588320 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Voltage-gated calcium channel activity
Specific Function:
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) and possibly T-type (CACNA1G). Overexpression induces apoptosis.
Gene Name:
CACNA2D2
Uniprot ID:
Q9NY47
Molecular Weight:
129816.095 Da
References
  1. Hota D, Bansal V, Pattanaik S: Evaluation of ketamine, nimodipine, gabapentin and imipramine in partial sciatic nerve transection model of neuropathic pain in rat: an experimental study. Methods Find Exp Clin Pharmacol. 2007 Sep;29(7):443-6. [PubMed:17982508 ]
  2. Gazulla J, Tintore MA: The P/Q-type voltage-dependent calcium channel as pharmacological target in spinocerebellar ataxia type 6: gabapentin and pregabalin may be of therapeutic benefit. Med Hypotheses. 2007;68(1):131-6. Epub 2006 Aug 8. [PubMed:16899342 ]
  3. Hendrich J, Van Minh AT, Heblich F, Nieto-Rostro M, Watschinger K, Striessnig J, Wratten J, Davies A, Dolphin AC: Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3628-33. doi: 10.1073/pnas.0708930105. Epub 2008 Feb 25. [PubMed:18299583 ]
  4. Hoffmann U, Dilekoz E, Kudo C, Ayata C: Gabapentin suppresses cortical spreading depression susceptibility. J Cereb Blood Flow Metab. 2010 Sep;30(9):1588-92. doi: 10.1038/jcbfm.2010.92. Epub 2010 Jun 30. [PubMed:20588320 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Voltage-gated calcium channel activity
Specific Function:
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-...
Gene Name:
CACNA1B
Uniprot ID:
Q00975
Molecular Weight:
262493.84 Da
References
  1. Cheng JK, Chen CC, Yang JR, Chiou LC: The antiallodynic action target of intrathecal gabapentin: Ca2+ channels, KATP channels or N-methyl-d-aspartic acid receptors? Anesth Analg. 2006 Jan;102(1):182-7. [PubMed:16368827 ]
  2. Hendrich J, Van Minh AT, Heblich F, Nieto-Rostro M, Watschinger K, Striessnig J, Wratten J, Davies A, Dolphin AC: Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin. Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3628-33. doi: 10.1073/pnas.0708930105. Epub 2008 Feb 25. [PubMed:18299583 ]
  3. Hoffmann U, Dilekoz E, Kudo C, Ayata C: Gabapentin suppresses cortical spreading depression susceptibility. J Cereb Blood Flow Metab. 2010 Sep;30(9):1588-92. doi: 10.1038/jcbfm.2010.92. Epub 2010 Jun 30. [PubMed:20588320 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
agonist
General Function:
Purine nucleoside binding
Specific Function:
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
Gene Name:
ADORA1
Uniprot ID:
P30542
Molecular Weight:
36511.325 Da
References
  1. De Vry J, Kuhl E, Franken-Kunkel P, Eckel G: Pharmacological characterization of the chronic constriction injury model of neuropathic pain. Eur J Pharmacol. 2004 May 3;491(2-3):137-48. [PubMed:15140630 ]
  2. Zuchora B, Wielosz M, Urbanska EM: Adenosine A1 receptors and the anticonvulsant potential of drugs effective in the model of 3-nitropropionic acid-induced seizures in mice. Eur Neuropsychopharmacol. 2005 Jan;15(1):85-93. [PubMed:15572277 ]
  3. Kralic JE, Criswell HE, Osterman JL, O'Buckley TK, Wilkie ME, Matthews DB, Hamre K, Breese GR, Homanics GE, Morrow AL: Genetic essential tremor in gamma-aminobutyric acidA receptor alpha1 subunit knockout mice. J Clin Invest. 2005 Mar;115(3):774-9. [PubMed:15765150 ]
Kind
Protein group
Organism
Human
Pharmacological action
unknown
General Function:
Voltage-gated cation channel activity
Specific Function:
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
Components:
NameUniProt IDDetails
Glutamate receptor ionotropic, NMDA 1Q05586 Details
Glutamate receptor ionotropic, NMDA 2AQ12879 Details
Glutamate receptor ionotropic, NMDA 2BQ13224 Details
Glutamate receptor ionotropic, NMDA 2CQ14957 Details
Glutamate receptor ionotropic, NMDA 2DO15399 Details
Glutamate receptor ionotropic, NMDA 3AQ8TCU5 Details
Glutamate receptor ionotropic, NMDA 3BO60391 Details
References
  1. Shimoyama M, Shimoyama N, Hori Y: Gabapentin affects glutamatergic excitatory neurotransmission in the rat dorsal horn. Pain. 2000 Apr;85(3):405-14. [PubMed:10781913 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
L-valine transaminase activity
Specific Function:
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
Gene Name:
BCAT1
Uniprot ID:
P54687
Molecular Weight:
42965.815 Da
References
  1. Goto M, Miyahara I, Hirotsu K, Conway M, Yennawar N, Islam MM, Hutson SM: Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. J Biol Chem. 2005 Nov 4;280(44):37246-56. Epub 2005 Sep 1. [PubMed:16141215 ]
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Drug created on June 13, 2005 07:24 / Updated on September 24, 2016 03:31