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Identification
NameCalcium
Accession NumberDB01373
TypeSmall Molecule
GroupsNutraceutical
Description

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast.

Structure
Thumb
SynonymsNot Available
External Identifiers Not Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Alka-cal Tabletstablet166.6 mgoralMorter HealthsystemNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Biost Powderpowder50 mgoralStandard Process Inc.Not applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Leucovorin Ca Inj (pharm. Bulk Vial) 10mg/mlliquid10 mgintravenousDavid Bull Laboratories (Pty) Ltd.1992-12-311997-08-14Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Pharmacal 500 Tab 500mgtablet500 mgPharmadex Laboratories Inc.1993-12-311999-08-28Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Generic Prescription ProductsNot Available
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
7030 Calcium Goldcapsule.99 1/1oralApexel Co., Ltd2013-03-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
7030 Calcium Premiumcapsule.99 1/1oralApexel Co., Ltd2013-03-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Bakanasan Calcium Citrate Powderpowder63.4 mgoralRheingold Food International Ltd.1995-12-311999-08-03Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Biocalth Calcium Powderpowder336 mgoralBiocalth International Corporation2003-05-102006-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Biocalth Calcium Supplementtablet100 mgoralBiocalth International Corporation2002-10-152006-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Bodysmarts With Calciumtablet30 mgoralCadbury Adams Canada Inc.2001-02-192005-07-28Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Cal 500 Tab 500mgtablet500 mgoralBioforce Canada Inc.1985-12-311997-04-04Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Cal Gel Cap 45mgcapsule45 mgoralLaboratoire Lalco Inc.1977-12-311997-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Cal Supp 500tablet500 mgoralWn Pharmaceuticals Ltd.2002-06-062006-08-08Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Cal Supp 500 - Tabtablet500 mgoralVita Health Products Inc1996-10-112008-08-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Cal-citrustablet200 mgoralSterimax Inc1996-09-102006-10-20Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcite 500 Tabtablet500 mgoralLaboratoire Riva Inc1985-12-312008-08-11Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calciumcapsule150 mgoralSeroyal International Inc.1996-12-312009-07-06Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calciumtablet500 mgoralHealth Wise Nutrition Inc.2000-04-042002-07-18Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium 350 Mg (calcium Citrate) - Caplettablet350 mgoralVita Health Products Inc1996-10-112007-07-30Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium 350 Mg (calcium Citrate) Caplettablet350 mgoralPurity Life Health Products A Division Of Sunopta Inc.2002-06-012008-07-07Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium 350mgtablet350 mgoralGeneral Nutrition Canada Inc.2001-10-202009-08-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium 500 mgtablet500 mgoralNutricorp International2001-11-012007-08-01Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium 500mgtablet500 mgoralWn Pharmaceuticals Ltd.1999-12-222009-09-28Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium 600tablet600 mgoralLaboratoire Riva Inc2001-01-152008-08-11Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium 600mg Dietary Supplementtablet600 mgoralGarden State Nutritionals1998-08-312000-06-07Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium 650mgtablet650 mgoralNutricorp International1999-12-152007-08-01Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium 650mg Tabtablet650 mgoralJamieson Laboratories Ltd1994-12-312006-07-25Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Caps 400mgcapsule400 mgoralTwin Laboratories Inc.1995-12-311999-11-10Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Carbonatetablet500 mgoralVita Health Products Inc1985-12-312004-07-26Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Carbonate 1500mgtablet600 mgoralWn Pharmaceuticals Ltd.2002-05-312007-08-07Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Carbonate Tabtablet246 mgoralSwiss Herbal Remedies Ltd.1989-12-311998-07-15Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Citramatecapsule160.0 mgoralThorne Research Inc.1997-04-182006-08-04Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Citratetablet350 mgoralHolista Health (Canada) Inc.2002-11-132008-07-17Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Citratetablet200 mgoralVita Health Products Inc1998-01-132004-07-26Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Citrate 300mgtablet300 mgoralWn Pharmaceuticals Ltd.1998-06-192008-07-17Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Gluconate Tablets USP 650 mgtablet60 mgoralPharmetics (2011) Inc2002-03-102006-07-27Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Lactate 650mgtablet120 mgoralGreat Earth Companies, Inc.1998-08-252002-10-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Lactate Capscapsule100 mgoralTwin Laboratories Inc.1995-12-311999-11-10Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Lactate Tab 84.5mgtablet84.5 mgoralLaboratoire Lalco Inc.1980-12-311997-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Lactate Tablets USP 650 mgtablet84 mgoralPharmetics (2011) Inc2002-03-102006-07-27Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Liquidliquid100 mgoralPharmetics (2011) Inc2002-09-302009-07-30Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Liquid Syrupsyrup100 mgoralSupplements Aromatik Inc.2003-07-022008-08-01Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Sandoz Syr 110mg/5mlsyrup110 mgoralNovartis Consumer Health Canada Inc.1995-12-311999-07-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Syrup 110mg/5mlsyrup110 mgoralVita Health Products Inc1990-12-312002-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calcium Tabletstablet158 mgoralDistributions Multi Pro Inc.1997-03-182000-06-07Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Calsan Chewable Tab 500mgtablet500 mgoralNovartis Consumer Health Canada Inc.1986-01-012008-07-15Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Chelated Calcium Supplement - 150mg Tabtablet150 mgoralAlbion Laboratories Inc.1996-09-062002-07-12Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Chelazome Calcium 125mgtablet125 mgoralTrophic Canada Ltd.1987-12-312000-08-03Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Children's Chewable Calcium (chewable Tablets)tablet266.7 mgoralGeneral Nutrition Canada Inc.1998-11-232007-08-01Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Coral Calciumpowder216.7 mgoralNature's Sunshine Products Of Canada Ltd.2003-12-012007-07-30Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Dia Cal Cap 500mgcapsule500 mgoralR & D Laboratories Inc.1991-12-312003-07-16Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ena Actimineral Aliquid803.8 mg/1000mLoralJinju Bio Food2013-06-28Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Extra Strength Calcium Antacid Chewabletablet300 mgoralPerrigo International1996-12-311998-08-12Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Gellucal Cap 45mgcapsule45 mgoralVitalab1990-12-311996-09-09Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Hantai 8030 Ca-D3 Goldtablet.99 1/1oralApexel Co., Ltd.2015-05-18Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Hantai 8030 Ca-D3 Premiumtablet.99 1/1oralApexel Co., Ltd.2015-05-18Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Hi Potency Cal Tab 650mgtablet650 mgoralSwiss Herbal Remedies Ltd.1986-12-311997-07-28Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Lactate De Calcium 648 mgtablet84.2 mgoralGamme Nature1990-12-312008-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Lactate De Calcium Tab 42.1mgtablet42.1 mgoralLe Naturiste J.M.B. Inc.1980-12-311997-07-23Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Mor-cal Tab 500mgtablet500 mgoralPharmetics (2011) Inc1986-12-312006-07-27Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Natu-cal Tab 500mgtablet500 mgoralLe Naturiste J.M.B. Inc.1987-12-312000-08-23Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Nutrol-cal Tab 875mgtablet350 mgoralRolmex International Inc.1990-12-311997-08-08Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Os-cal 250 mgtablet250 mgoralWyeth Canada1994-12-312003-07-28Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Os-cal 500tablet500 mgoralWyeth Canada1993-12-312008-12-16Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Os-cal 500 Chewable Tab 500mgtablet500 mgoralAyerst Laboratories1986-12-311997-08-15Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Os-cal 500 Chewable Tab 500mgtablet500 mgoralWyeth Ayerst Canada Inc.1996-09-301998-01-28Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Oystershell Calcium 250mg Tabletstablet250 mgoralGeneral Nutrition Canada Inc.1997-04-182005-08-05Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Prevencal Tab 500mgtablet500 mgoralLaboratoire Lalco Inc.1988-12-311997-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Regular Strength Calcium Antacid Chew. Tabstablet200 mgoralPerrigo International1996-12-311998-08-12Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Soluble Calcium Citrate 1200mgtablet250 mgoralGreat Earth Companies, Inc.1998-08-252002-10-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Tropicana Calcium Supplement 344 mgsolution1.458 mgoralTropicana Canada2002-01-142007-06-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Tropicana Calcium Supplement 393 mgsolution1.667 mgoralTropicana Canada2002-02-182007-06-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Tropicana Calcium Supplement 604 mgsolution1.458 mgoralTropicana Canada2003-02-072007-06-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Tums 500 Tabtablet500 mgoralSmithkline Beecham Consumer Healthcare, Division Of Smithkline Beecham Inc.1994-12-311996-09-12Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Tums Extra Strength Assorted Tropical Fruittablet300 mgoralSmithkline Beecham Consumer Healthcare, Division Of Smithkline Beecham Inc.1996-09-101998-08-25Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Tums Ultra Strength Assorted Mint Flavourstablet400 mgoralSmithkline Beecham Consumer Healthcare, Division Of Smithkline Beecham Inc.1996-12-311998-08-25Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Tums Ultra Strength Assorted Tropical Fruittablet400 mgoralSmithkline Beecham Consumer Healthcare, Division Of Smithkline Beecham Inc.1997-07-311998-08-25Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Tums Ultra Strength Liquidliquid400 mgoralSmithkline Beecham Consumer Healthcare, Division Of Smithkline Beecham Inc.1997-04-172001-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Vitamine C Cap 600mgcapsule600 mgoralSisu Inc.1989-12-312008-07-25Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Webber Calcium Tab 500mgtablet500 mgoralNovartis Consumer Health Canada Inc.1985-12-311998-07-08Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
International BrandsNot Available
Brand mixtures
NameLabellerIngredients
Act EtidrocalActavis Pharma Company
Acti-cal/mag 2:1 + Zinc and D CapletActi Form Ltd.
Acti-megascorb Crystals PwrActi Form Ltd.
Actonel Plus CalciumWarner Chilcott Canada Co
Actonel Sachet KitWarner Chilcott Canada Co
Astral C TabAlbi Naturals
Avon Nutrivance Soft Calcium Chews With Vitamin DAvon Canada Ulc
B-nexaUpsher Smith Laboratories, Inc.
BaisixProdemdis Enr.
Buffered Vitamin C Powder With Ca Mg and KThorne Research Canada Ltd.
C-crystals With CalciumAlive Vitamins
Cal & Mag Hvp Chel Plus C Potass & Zinc TabGahler Enterprises Ltd.
Cal Mag Drink With Vitamin CWampole Brands
Cal Mag TabSwiss Herbal Remedies Ltd.
Cal-mag (one To One) With Potass & ZincGahler Enterprises Ltd.
Cal-mag Citrate Zinc & Vitamin D TabletsSwiss Herbal Remedies Ltd.
Cal-mag Complete With Zinc, C and DQuest Vitamins A Div Of Purity Life Health Products
Cal-mag TabletStandard Process Inc.
Cal-mag Vitamin C and Zinc TabSwiss Herbal Remedies Ltd.
Cal-mag With Zinc & Vitamin DHealth Wise Nutrition Inc.
Cal-mag Zinc TabPro Shop Inc.
Cal/mag 1:1 With Zinc and Vitamin D - TabletHealth Wise Nutrition Inc.
Cal/mag 2001 Plus Vitamins C and DDouglas Laboratories
Cal/mag 2:1 With DWn Pharmaceuticals Ltd.
Calci-yum Plus Magnesium + D3Nu Life Nutrition Ltd.
Calcimag TabLes Produits Naturels Suisse Inc.
Calcium Mg and Zn Capsules With Vitamin DRheingold Food International Ltd.
Calcium & MagnesiumWn Pharmaceuticals Ltd.
Calcium & Magnesium Plus Potassium & ZincNatural Factors Nutritional Products Ltd.
Calcium & Magnesium TabPharmavite Llc
Calcium & Magnesium TabletsVita Health Products Inc
Calcium & Magnesium With Potassium & ZincWn Pharmaceuticals Ltd.
Calcium & Vitamin DQuantofill Inc.
Calcium & Vitamin D TabletsViva Pharmaceutical Inc.
Calcium 250 Mg With Vitamin DGfr Pharma Ltd.
Calcium 250mg With Vitamin DWn Pharmaceuticals Ltd.
Calcium 400 With Magnesium - PwrHillestad Pharmaceuticals Usa
Calcium 500 Mg + Vitamin DHolista Health (Canada) Inc.
Calcium 500mg & Vitamin D 200I.U.Swiss Herbal Remedies Ltd.
Calcium 500mg With Vitamin DWn Pharmaceuticals Ltd.
Calcium 600 + DLaboratoire Riva Inc
Calcium 600mg + Vit D3 125unit TabPharmetics (2011) Inc
Calcium and Mag-potass and Zinc CapGahler Enterprises Ltd.
Calcium and MagnesiumVita Health Products Inc
Calcium and Magnesium CapsulesRheingold Food International Ltd.
Calcium and Magnesium Citrate and Vitamin D 250mg/125mg/200iuWn Pharmaceuticals Ltd.
Calcium and Magnesium SupplPharmavite Llc
Calcium and Magnesium Supplement TabHall Laboratories, Ltd.
Calcium and Magnesium TabAlbi Imports Ltd.
Calcium and Magnesium TabletsVitazan Herbs & Vitamins Inc.
Calcium and Magnesium W Zinc TabPharmavite Llc
Calcium and Magnesium With Vitamin DVita Health Products Inc
Calcium and Magnesium With ZincVita Health Products Inc
Calcium Ascorbate 1000 Mg - TabletHealth Wise Nutrition Inc.
Calcium Ascorbate Cap 850mgQuest Vitamins A Div Of Purity Life Health Products
Calcium Ascorbate Tab 550mgEster C Health Co, Division Of Inter Cal Corp
Calcium Caps Plus MagnesiumTwin Laboratories Inc.
Calcium Chelate Plus Vit DHall Laboratories, Ltd.
Calcium Citrate and Vitamin D 200mg/160iuWn Pharmaceuticals Ltd.
Calcium Citrate With Vitamin DWn Pharmaceuticals Ltd.
Calcium Et Magnesium Plus Vitamin DLaboratoire Lalco Inc.
Calcium Et Magnesium TabLaboratoire Lalco Inc.
Calcium Lactate PowderStandard Process Inc.
Calcium Magnesium 1000/500 - TabPro Shop Inc.
Calcium Magnesium 2:1 Tablets With Vitamin DSisu Inc.
Calcium Magnesium and Zinc TabRheingold Food International Ltd.
Calcium Magnesium Avec Vitamine CLes Aliments Nutri Source Inc.
Calcium Magnesium From Dolomite Nu LifeNu Life Nutrition Ltd.
Calcium Magnesium Plus DNutrimetics International (Canada) Inc.
Calcium Magnesium TabNutricorp International
Calcium Magnesium Tablets Nu LifeNu Life Nutrition Ltd.
Calcium Magnesium W Vit D3Avacare, Division Of Jeunique International Inc.
Calcium Magnesium With Potassium TabNutrition For Life International
Calcium With Vitamin D 200 Mg/160 IuWn Pharmaceuticals Ltd.
Calcium With Vitamin D2Sisu Inc.
Calcium With Vitamins C and D TabPure Life International Prods Inc.
Calcium, Magnesium Et Vitamine DGamme Nature
Calcium, Magnesium With Vitamin D and ZincPharmetics (2011) Inc
Calcium-iron-magnesium With A,d,c TabBioforce Canada Inc.
Calcium-magnesium With K & Zn and Vitamin D3Holista Health (Canada) Inc.
Calcium/magnesium DrinkNew Vision Nutritionals Company
Calcium/magnesium Supplement TabletsGeneral Nutrition Canada Inc.
Calcium/magnesium/vitamin D - CapsuleHolista Health (Canada) Inc.
Calma-DWn Pharmaceuticals Ltd.
CalmaxMedia Power, Inc.
Caltrate 600 Plus D - TabletWhitehall Robins Inc.
Chela Calmag-100 Plus Zinc D3Nu Life Nutrition Ltd.
Chela Calmag-300 Plus Zinc D3Nu Life Nutrition Ltd.
Chelated Calcium and Magnesium TabAlive Vitamins
Chewable Cal-mag Chocolate FlavourViva Life Science, Inc.
Chewable Calcium & Magnesium 2:1 TabletSwiss Herbal Remedies Ltd.
Chewable Children's Complete Multivitamins With Essential MineralsWn Pharmaceuticals Ltd.
Children's Chewable Multi-vitamin Complete With MineralsWn Pharmaceuticals Ltd.
Children's Chewable Multivitamins With MineralsWn Pharmaceuticals Ltd.
Congaplex CapStandard Process Inc.
Coral Calcium Plus Vitamin D 210mg/100iuWn Pharmaceuticals Ltd.
DidrocalWarner Chilcott Canada Co
Dol Mite TabSwiss Herbal Remedies Ltd.
Dolomite 1280mgRay Irastorza
Dolomite Tab 650mgJamieson Laboratories Ltd
Dolomite TabletsVita Health Products Inc
Domex TabSantÉ Naturelle (Ag) LtÉe
Efferlife Calcium 500mg + Vitamin D3 440 Iu + Vitamin C 125mgNaturale Science Inc.
Effervescent Vitamin C Powder With Ca and mgThorne Research Canada Ltd.
Ester C 500 TabNu Life Nutrition Ltd.
Ester C Calcium Ascorbate CapNatrol, Inc.
Ester C CapsuleNatural Factors Nutritional Products Ltd.
Ester C PowderNatural Factors Nutritional Products Ltd.
Ester C Tab ChewableNatrol, Inc.
Ester C Vitamin C and Calcium PwsNatrol, Inc.
Ester-CNatural Factors Nutritional Products Ltd.
Ester-C 500 mgWn Pharmaceuticals Ltd.
Ester-C 600 mgWn Pharmaceuticals Ltd.
Ester-C 787mgNatural Factors Nutritional Products Ltd.
Ester-C Calcium Ascor TabNatrol, Inc.
Ester-C Calcium Ascorbate CapsulesSwiss Herbal Remedies Ltd.
Ester-C Calcium Ascorbate TabNatrol, Inc.
Ester-C Calcium Ascorbate TabletsSwiss Herbal Remedies Ltd.
Ester-C PowderNatural Factors Nutritional Products Ltd.
Ester-C TabletNatural Factors Nutritional Products Ltd.
Ester-C Vitamin C With CalciumDarwen Holdings Ltd.
EtidrocalSanis Health Inc
Feminique W Iron and Calcium TabStanley Pharmaceuticals, A Division Of Vita Health Products Inc.
Ferrous SulfateMartin Ekwealor Pharmaceuticals, Inc.
Flex CapsulesFoodscience Laboratories, Division Of Foodscience Corporation
Folcaps Omega-3Midlothian Laboratories
Formula A.R.-th Dietary SupplementRx Vitamins Inc.
Gnc Calcium With Magnesium and Vitamin DGeneral Nutrition Canada Inc.
Hormodausse Plus Calc Et D TabLaboratoires Charton Laboratories
Hvp Chelated Cal/mag With Zinc and Vitamins C and DDarwen Holdings Ltd.
IfbVisiontel
IpricalPep Products Inc.
Isotonix Calcium Plus FormulaMarket America, Inc.
Kids Chewable Cal/magQuixtar Canada Corporation
Kos-mag +cNutritia International Laboratoire
Leritone AntistressInstitut De Recherche Biologique Yves Ponroy Canada Inc.
Liqui Cal-DTwin Laboratories Inc.
Liquid Cal-magSeroyal International Inc.
Liquid Cal/mag Plus DGahler Enterprises Ltd.
Liquid Calcium and Magnesium With Vit.dRheingold Food International Ltd.
MagnacalHolista Health (Canada) Inc.
Menocal TabLes Aliments Nutri Source Inc.
Mid-life Magnacal 2Holista Health (Canada) Inc.
Min-tran TabStandard Process Inc.
Min-trax TabTherapeutic Foods Co.
Mnps Formula SupplementGarden State Nutritionals
Multi #2W 7 Clay Inc.
Multi Vitamin & MineralsWn Pharmaceuticals Ltd.
Multi-min Electro C Pow Plus B2Quest Vitamins A Div Of Purity Life Health Products
Multiple Mineral LiquidEnrich International
Mylan-eti-cal CarepacMylan Pharmaceuticals Ulc
Nata KompleteWh Nutritionals, Llc
Natelle OneMEDA Pharmaceuticals
Nexa PlusUpsher Smith Laboratories, Inc.
Nexa Select Rx Prenatal Vitamin With Plant-based DHAUpsher Smith Laboratories, Inc.
Ni-C-E-LE PlusNutrimetics International (Canada) Inc.
Novo-etidronatecalTeva Canada Limited
Ntp-etidronate CalciumTeva Canada Limited
Nutravite Calcium Magnesium and Zinc CapsNutravite Pharmaceuticals Inc.
Nutri-chem Cal MagNutri Chem Pharmacy Ltd
Nutri-chem Calcium Magnesium With D and ZincNutri Chem Pharmacy Ltd
O Calcium 500mg Plus D TabVita Health Products Inc
O-cal Prenatal VitaminPharmics, Inc.
O-calcium 250mg Plus DVita Health Products Inc
One To One Cal-mag Tab 500mgGahler Enterprises Ltd.
Opti-cal Chewable +d CapletNu Life Nutrition Ltd.
Osteo FormulaNutramed Laboratories Inc.
Osteo-lifeViva Pharmaceutical Inc.
Osteo-plusRolmex International Inc.
OsteoligoClinique Lafontaine Inc, Division Les Importations Ortho
Oyster Shell Calcium With Vitamin DCardinal Health
PMS-risedronate Plus CalciumPharmascience Inc
Port A Mins Super Cal-mag 300/150 With Vitamin D3Great Earth Companies, Inc.
Port A Mins Super Cal-mag 600/300Great Earth Companies, Inc.
Port A Mins Super Cal-mag-zincGreat Earth Companies, Inc.
Port A Mins Super Calcium 375 With Vitamin D3Great Earth Companies, Inc.
Port A Mins Super Calcium 750 With Vitamin D3Great Earth Companies, Inc.
PremelLe Naturiste J.M.B. Inc.
Prenatal Vitamins Plusbryant ranch prepack
Pure Calcium CalciumSaimdang Cosmetics Co., Ltd
Redoxon-calBayer Inc Consumer Care
ReebokClearly Canadian Beverage Corporation
Rolaids Extra Strength TabWarner Lambert Canada Inc.
Somarexin and C 1000Laboratoire Lalco Inc.
Stressease Plus Vitamins and MineralsJamieson Laboratories Ltd
Super C Crystals W CalciumNu Life Nutrition Ltd.
Super C-M-KCreative Nutrition Canada Corp.
Supplement De Vitamines Et MinerauxLand Art Inc.
Swical-1 TabLes Aliments Nutri Source Inc.
Swical-2 TabLes Aliments Nutri Source Inc.
T-PA CapSeroyal International Inc.
Tianshi Calcium With Natural Source Vitamin E Softgel CapsulesTianjin Tianshi Group Co., Ltd.
Timed Release and Esterified Vitamin C-500Great Earth Companies, Inc.
Timed Release Ester-C 1000mgSwiss Herbal Remedies Ltd.
Tri-mins - CapAlbion Laboratories Inc.
Tropicana Calcium & Vitamin C SupplementTropicana Canada
Tropicana Calcium and Vitamin C SupplementTropicana Canada
Vit C Cap W Calc Magn & PotassiumSisu Inc.
Vit C W Calc-mag and Potass PowderNf Formulas Inc.
Vita - Gl CapsulesAnton Hubner Gmbh & Co.
Vitafol CapletEverett Laboratories, Inc.
Vitafol Ob CapletEverett Laboratories, Inc.
Vitamin C and Calcium TabNatrol, Inc.
Vitamin C Calcium PwrSisu Inc.
Vitamines A - D CalciumLaboratoire Lalco Inc.
ZingiberPru Gen, Inc. Pharmaceuticals
Salts
Name/CASStructureProperties
Calcium acetate
ThumbNot applicableDBSALT001052
CategoriesNot Available
UNIISY7Q814VUP
CAS number7440-70-2
WeightAverage: 40.078
Monoisotopic: 39.962591155
Chemical FormulaCa
InChI KeyInChIKey=OYPRJOBELJOOCE-UHFFFAOYSA-N
InChI
InChI=1S/Ca
IUPAC Name
calcium
SMILES
[Ca]
Taxonomy
ClassificationNot classified
Pharmacology
IndicationCalcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. It is vital in cell signaling, muscular contractions, bone health, and signalling cascades.
PharmacodynamicsCalcium (Ca2+) plays a pivotal role in the physiology and biochemistry of organisms and the cell. It plays an important role in signal transduction pathways, where it acts as a second messenger, in neurotransmitter release from neurons, contraction of all muscle cell types, and fertilization. Many enzymes require calcium ions as a cofactor, those of the blood-clotting cascade being notable examples. Extracellular calcium is also important for maintaining the potential difference across excitable cell membranes, as well as proper bone formation.
Mechanism of actionCalcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. More than 500 human proteins are known to bind or transport calcium. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Parathyroid hormone (secreted from the parathyroid gland) regulates the resorption of Ca2+ from bone. Calcitonin stimulates incorporation of calcium in bone, although this process is largely independent of calcitonin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast. The currently recommended calcium intake is 1,500 milligrams per day for women not taking estrogen and 800 milligrams per day for women on estrogen. There is close to 300 milligrams of calcium in one cup of fluid milk. Calcium carbonate is currently the best and least expensive form of calcium supplement available.
AbsorptionNot Available
Volume of distributionNot Available
Protein bindingNot Available
MetabolismNot Available
Route of eliminationThe kidney excretes 250 mmol a day in urine, and resorbs 245 mmol, leading to a net loss in the urine of 5 mmol/d.
Half lifeNot Available
ClearanceNot Available
ToxicityNot Available
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal AbsorptionNot AvailableNot Available
Blood Brain BarrierNot AvailableNot Available
Caco-2 permeableNot AvailableNot Available
P-glycoprotein substrateNot AvailableNot Available
P-glycoprotein inhibitor INot AvailableNot Available
P-glycoprotein inhibitor IINot AvailableNot Available
Renal organic cation transporterNot AvailableNot Available
CYP450 2C9 substrateNot AvailableNot Available
CYP450 2D6 substrateNot AvailableNot Available
CYP450 3A4 substrateNot AvailableNot Available
CYP450 1A2 substrateNot AvailableNot Available
CYP450 2C9 inhibitorNot AvailableNot Available
CYP450 2D6 inhibitorNot AvailableNot Available
CYP450 2C19 inhibitorNot AvailableNot Available
CYP450 3A4 inhibitorNot AvailableNot Available
CYP450 inhibitory promiscuityNot AvailableNot Available
Ames testNot AvailableNot Available
CarcinogenicityNot AvailableNot Available
BiodegradationNot AvailableNot Available
Rat acute toxicityNot AvailableNot applicable
hERG inhibition (predictor I)Not AvailableNot Available
hERG inhibition (predictor II)Not AvailableNot Available
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
ManufacturersNot Available
Packagers
Dosage forms
FormRouteStrength
Capsuleoral.99 1/1
Powderoral
Granules (effervescents); kit; tabletoral
Tabletoral166.6 mg
Piece (chewable)oral
Tabletoral
Powderoral63.4 mg
Powderoral336 mg
Tabletoral100 mg
Powderoral50 mg
Tabletoral30 mg
Capsuleoral150 mg
Tabletoral600 mg
Tabletoral650 mg
Capsuleoral400 mg
Tabletoral246 mg
Capsuleoral160.0 mg
Tabletoral60 mg
Tabletoral120 mg
Capsuleoral100 mg
Tabletoral84.5 mg
Tabletoral84 mg
Liquidoral100 mg
Syruporal100 mg
Syruporal110 mg
Tabletoral158 mg
Tabletoral150 mg
Tabletoral125 mg
Tabletoral266.7 mg
Powderoral216.7 mg
Capsuleoral500 mg
Kit; tabletoral
Liquidoral803.8 mg/1000mL
Powder for solutionoral
Tabletoral300 mg
Capsuleoral45 mg
Tabletoral.99 1/1
Tablet
Tabletoral84.2 mg
Tabletoral42.1 mg
Liquidintravenous10 mg
Liquidoral
Powder (effervescent)oral
Capsule, gelatin coatedoral
Capsuleoral
Tabletoral350 mg
Tabletoral250 mg
Tablet, film coatedoral
Tablet500 mg
Tablet, chewableoral
Tablet (effervescent)oral
Tabletoral200 mg
Liquid; tabletoral
Tablet (extended-release)oral
Solutionoral1.458 mg
Solutionoral1.667 mg
Tabletoral400 mg
Liquidoral400 mg
Capsuleoral600 mg
Tabletoral500 mg
PricesNot Available
PatentsNot Available
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point839°CMSDS
boiling point1484°CMSDS
Predicted Properties
PropertyValueSource
Water Solubility0.0 mg/mLALOGPS
logP-1.3ALOGPS
logP-0.57ChemAxon
logS1.08ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
References
Synthesis ReferenceUS5667761
General References
  1. Dawson-Hughes B, Harris SS, Krall EA, Dallal GE: Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med. 1997 Sep 4;337(10):670-6. Pubmed
  2. Weingarten MA, Zalmanovici A, Yaphe J: Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps. Cochrane Database Syst Rev. 2005 Jul 20;(3):CD003548. Pubmed
  3. Jackson RD, LaCroix AZ, Gass M, Wallace RB, Robbins J, Lewis CE, Bassford T, Beresford SA, Black HR, Blanchette P, Bonds DE, Brunner RL, Brzyski RG, Caan B, Cauley JA, Chlebowski RT, Cummings SR, Granek I, Hays J, Heiss G, Hendrix SL, Howard BV, Hsia J, Hubbell FA, Johnson KC, Judd H, Kotchen JM, Kuller LH, Langer RD, Lasser NL, Limacher MC, Ludlam S, Manson JE, Margolis KL, McGowan J, Ockene JK, O’Sullivan MJ, Phillips L, Prentice RL, Sarto GE, Stefanick ML, Van Horn L, Wactawski-Wende J, Whitlock E, Anderson GL, Assaf AR, Barad D: Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med. 2006 Feb 16;354(7):669-83. Pubmed
  4. Grant AM, Avenell A, Campbell MK, McDonald AM, MacLennan GS, McPherson GC, Anderson FH, Cooper C, Francis RM, Donaldson C, Gillespie WJ, Robinson CM, Torgerson DJ, Wallace WA: Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium Or vitamin D, RECORD): a randomised placebo-controlled trial. Lancet. 2005 May 7-13;365(9471):1621-8. Pubmed
  5. Porthouse J, Cockayne S, King C, Saxon L, Steele E, Aspray T, Baverstock M, Birks Y, Dumville J, Francis R, Iglesias C, Puffer S, Sutcliffe A, Watt I, Torgerson DJ: Randomised controlled trial of calcium and supplementation with cholecalciferol (vitamin D3) for prevention of fractures in primary care. BMJ. 2005 Apr 30;330(7498):1003. Pubmed
External Links
ATC CodesNot Available
AHFS Codes
  • 34:00.00
  • 40:12.00
  • 40:18.17
  • 40:18.19
  • 40:34.00*
  • 56:04.00
  • 56:12.00
  • 88:08.00
  • 88:12.00
  • 88:29.00*
  • 92:02.00*
PDB EntriesNot Available
FDA labelDownload (25.6 KB)
MSDSDownload (47.9 KB)
Interactions
Drug InteractionsNot Available
Food InteractionsNot Available

Targets

1. Voltage-dependent L-type calcium channel subunit alpha-1C

Kind: Protein

Organism: Human

Pharmacological action: yes

Actions: ligand

Components

Name UniProt ID Details
Voltage-dependent L-type calcium channel subunit alpha-1C Q13936 Details

References:

  1. Boda D, Giri J, Henderson D, Eisenberg B, Gillespie D: Analyzing the components of the free-energy landscape in a calcium selective ion channel by Widom’s particle insertion method. J Chem Phys. 2011 Feb 7;134(5):055102. Pubmed

2. Calcium-transporting ATPase type 2C member 1

Kind: Protein

Organism: Human

Pharmacological action: yes

Actions: agonist

Components

Name UniProt ID Details
Calcium-transporting ATPase type 2C member 1 P98194 Details

References:

  1. Shi X, Chen M, Huvos PE, Hardwicke PM: Amino acid sequence of a Ca(2+)-transporting ATPase from the sarcoplasmic reticulum of the cross-striated part of the adductor muscle of the deep sea scallop: comparison to serca enzymes of other animals. Comp Biochem Physiol B Biochem Mol Biol. 1998 Jun;120(2):359-74. Pubmed
  2. Bonza MC, Martin H, Kang M, Lewis G, Greiner T, Giacometti S, Van Etten JL, De Michelis MI, Thiel G, Moroni A: A functional calcium-transporting ATPase encoded by chlorella viruses. J Gen Virol. 2010 Oct;91(Pt 10):2620-9. Epub 2010 Jun 23. Pubmed

3. Troponin C, skeletal muscle

Kind: Protein

Organism: Human

Pharmacological action: yes

Actions: agonist

Components

Name UniProt ID Details
Troponin C, skeletal muscle P02585 Details

References:

  1. Martin SR, Avella G, Adrover M, de Nicola GF, Bullard B, Pastore A: Binding Properties of the Calcium-Activated F2 Isoform of Lethocerus Troponin C. Biochemistry. 2011 Feb 10. Pubmed
  2. Kreutziger KL, Piroddi N, McMichael JT, Tesi C, Poggesi C, Regnier M: Calcium binding kinetics of troponin C strongly modulate cooperative activation and tension kinetics in cardiac muscle. J Mol Cell Cardiol. 2011 Jan;50(1):165-74. Epub 2010 Oct 28. Pubmed
  3. Robertson IM, Sun YB, Li MX, Sykes BD: A structural and functional perspective into the mechanism of Ca2+-sensitizers that target the cardiac troponin complex. J Mol Cell Cardiol. 2010 Dec;49(6):1031-41. Epub 2010 Aug 27. Pubmed
  4. Dweck D, Reynaldo DP, Pinto JR, Potter JD: A dilated cardiomyopathy troponin C mutation lowers contractile force by reducing strong myosin-actin binding. J Biol Chem. 2010 Jun 4;285(23):17371-9. Epub 2010 Apr 6. Pubmed

4. Troponin C, slow skeletal and cardiac muscles

Kind: Protein

Organism: Human

Pharmacological action: yes

Actions: agonist

Components

Name UniProt ID Details
Troponin C, slow skeletal and cardiac muscles P63316 Details

References:

  1. Dweck D, Reynaldo DP, Pinto JR, Potter JD: A dilated cardiomyopathy troponin C mutation lowers contractile force by reducing strong myosin-actin binding. J Biol Chem. 2010 Jun 4;285(23):17371-9. Epub 2010 Apr 6. Pubmed
  2. Swindle N, Tikunova SB: Hypertrophic cardiomyopathy-linked mutation D145E drastically alters calcium binding by the C-domain of cardiac troponin C. Biochemistry. 2010 Jun 15;49(23):4813-20. Pubmed
  3. Parvatiyar MS, Pinto JR, Liang J, Potter JD: Predicting cardiomyopathic phenotypes by altering Ca2+ affinity of cardiac troponin C. J Biol Chem. 2010 Sep 3;285(36):27785-97. Epub 2010 Jun 21. Pubmed
  4. Baylor SM, Hollingworth S: Calcium indicators and calcium signalling in skeletal muscle fibres during excitation-contraction coupling. Prog Biophys Mol Biol. 2010 Jun 25. Pubmed

5. Spectrin beta chain, non-erythrocytic 1

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: agonist

Components

Name UniProt ID Details
Spectrin beta chain, non-erythrocytic 1 Q01082 Details

References:

  1. Wallis CJ, Wenegieme EF, Babitch JA: Characterization of calcium binding to brain spectrin. J Biol Chem. 1992 Mar 5;267(7):4333-7. Pubmed

6. Protein S100-B

Kind: Protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Protein S100-B P04271 Details

References:

  1. Lee TS, Mane S, Eid T, Zhao H, Lin A, Guan Z, Kim JH, Schweitzer J, King-Stevens D, Weber P, Spencer SS, Spencer DD, de Lanerolle NC: Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes. Mol Med. 2007 Jan-Feb;13(1-2):1-13. Pubmed
  2. Marlatt NM, Shaw GS: Amide exchange shows calcium-induced conformational changes are transmitted to the dimer interface of S100B. Biochemistry. 2007 Jun 26;46(25):7478-87. Epub 2007 May 31. Pubmed
  3. Liang J, Luo G, Ning X, Shi Y, Zhai H, Sun S, Jin H, Liu Z, Zhang F, Lu Y, Zhao Y, Chen X, Zhang H, Guo X, Wu K, Fan D: Differential expression of calcium-related genes in gastric cancer cells transfected with cellular prion protein. Biochem Cell Biol. 2007 Jun;85(3):375-83. Pubmed
  4. Friel LA, Romero R, Edwin S, Nien JK, Gomez R, Chaiworapongsa T, Kusanovic JP, Tolosa JE, Hassan SS, Espinoza J: The calcium binding protein, S100B, is increased in the amniotic fluid of women with intra-amniotic infection/inflammation and preterm labor with intact or ruptured membranes. J Perinat Med. 2007;35(5):385-93. Pubmed

7. Calpastatin

Kind: Protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Calpastatin P20810 Details

References:

  1. Hanna RA, Garcia-Diaz BE, Davies PL: Calpastatin simultaneously binds four calpains with different kinetic constants. FEBS Lett. 2007 Jun 26;581(16):2894-8. Epub 2007 May 25. Pubmed
  2. De Tullio R, Averna M, Stifanese R, Parr T, Bardsley RG, Pontremoli S, Melloni E: Multiple rat brain calpastatin forms are produced by distinct starting points and alternative splicing of the N-terminal exons. Arch Biochem Biophys. 2007 Sep 1;465(1):148-56. Epub 2007 May 30. Pubmed

8. Cartilage oligomeric matrix protein

Kind: Protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Cartilage oligomeric matrix protein P49747 Details

References:

  1. Chen FH, Herndon ME, Patel N, Hecht JT, Tuan RS, Lawler J: Interaction of cartilage oligomeric matrix protein/thrombospondin 5 with aggrecan. J Biol Chem. 2007 Aug 24;282(34):24591-8. Epub 2007 Jun 22. Pubmed

9. Calmodulin

Kind: Protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Calmodulin P62158 Details

References:

  1. Sosa V, Carbo R, Guarner V: Participation of glucose transporters on atrial natriuretic peptide-induced glucose uptake by adult and neonatal cardiomyocytes under oxygenation and hypoxia. Eur J Pharmacol. 2007 Jul 30;568(1-3):83-8. Epub 2007 Apr 30. Pubmed
  2. Zhou Z, Yin J, Dou Z, Tang J, Zhang C, Cao Y: The calponin homology domain of Vav1 associates with calmodulin and is prerequisite to T cell antigen receptor-induced calcium release in Jurkat T lymphocytes. J Biol Chem. 2007 Aug 10;282(32):23737-44. Epub 2007 Jun 5. Pubmed
  3. Schallreuter KU, Gibbons NC, Zothner C, Abou Elloof MM, Wood JM: Hydrogen peroxide-mediated oxidative stress disrupts calcium binding on calmodulin: more evidence for oxidative stress in vitiligo. Biochem Biophys Res Commun. 2007 Aug 17;360(1):70-5. Epub 2007 Jun 11. Pubmed
  4. Caride AJ, Filoteo AG, Penniston JT, Strehler EE: The plasma membrane Ca2+ pump isoform 4a differs from isoform 4b in the mechanism of calmodulin binding and activation kinetics: implications for Ca2+ signaling. J Biol Chem. 2007 Aug 31;282(35):25640-8. Epub 2007 Jun 26. Pubmed
  5. Lo LW, Chen YC, Chen YJ, Wongcharoen W, Lin CI, Chen SA: Calmodulin kinase II inhibition prevents arrhythmic activity induced by alpha and beta adrenergic agonists in rabbit pulmonary veins. Eur J Pharmacol. 2007 Oct 1;571(2-3):197-208. Epub 2007 Jun 13. Pubmed

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Drug created on July 06, 2007 14:28 / Updated on March 14, 2014 14:36