| Version |
2.5 |
| Creation Date |
2007-07-24 09:23:59 |
| Update Date |
2009-02-19 16:04:38 |
| Primary Accession Number |
DB01420 |
| Secondary Accession Number |
Not Available |
| Name |
Testosterone Propionate |
| Drug Type |
|
| Description |
An ester of testosterone with a propionate substitution at the 17-beta position. [PubChem] |
| Synonyms |
Not Available |
| Brand Names |
- Agovirin
- Testex
|
| Brand Mixtures |
Not Available |
| Chemical IUPAC Name |
[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate |
| Chemical Formula |
C22H32O3 |
| Chemical Structure |
 |
| CAS Registry Number |
57-85-2 |
| InChI Identifier |
InChI=1/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1 |
| InChI Key |
PDMMFKSKQVNJMI-BLQWBTBKBT |
| KEGG Drug |
D00959  |
| KEGG Compound |
C08158 |
| PubChem Compound |
5995 |
| PubChem Substance |
7848022 |
| ChEBI ID |
Not Available |
| PharmGKB ID |
Not Available |
| HET ID |
Not Available |
| GenBank ID |
Not Available |
| Drug ID Number [DIN] |
Not Available |
| RxList Link |
Not Available |
| PDRhealth Link |
Not Available |
| Wikipedia Link |
Not Available |
| FDA Label |
Not Available |
| Material Safety Data Sheet (MSDS) |
Not Available |
| Synthesis Reference |
Not Available |
| Average Molecular Weight |
344.4877 |
| Monoisotopic Molecular Weight |
344.2351 |
| State |
Solid |
| Melting Point |
Not Available |
| Experimental Water Solubility |
Not Available
Source: PhysProp
|
| Predicted Water Solubility |
5.02e-03 mg/mL
Calculated using ALOGPS
|
| Experimental LogP/Hydrophobicity |
Not Available
Source: PhysProp
|
| Predicted LogP |
3.65
Calculated using ALOGPS
|
| Experimental LogS |
-5.37 [ADME Research, USCD] |
| Predicted LogS |
-4.84
Calculated using ALOGPS
|
| Experimental Caco2 Permeability |
Not Available |
| pKa/Isoelectric Point |
Not Available |
| Mass Spectrum |
Not Available
|
| MOL File |
Show | Download |
| SDF File |
Show | Download |
| PDB File |
Show | Download |
| 2D Structure |
|
| 3D Structure |
|
| Experimental PDB ID |
Not Available |
| Isomeric SMILES |
CCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C |
| Canonical SMILES |
CCC(=O)OC1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C |
| Drug Category |
Not Available |
| ATC Codes |
|
| AHFS Codes |
|
| Indication |
Not Available |
| Pharmacology |
Not Available |
| Mechanism of Action |
Not Available |
| Absorption |
Not Available |
| Toxicity |
Not Available |
| Protein Binding |
Not Available |
| Biotransformation |
Not Available |
| Half Life |
Not Available |
| Dosage Forms |
| Form |
Route |
| Capsule |
Oral |
| Gel |
Topical |
| Liquid |
Intramuscular |
| Patch |
Transdermal |
| Solution |
Intramuscular |
|
| Patient Information |
Not Available |
| Contraindications |
Not Available |
| Interactions |
Not Available |
| Drug Interactions |
| Drug |
Interaction |
| Acenocoumarol |
The androgen, Testosterone, may incrase the anticoagulant effect of the Vitamin K antagonist, Acenocoumarol. Monitor for changes in the therapeutic effect of Acenocoumarol if Testosterone is initiated, discontinued or dose changed. |
| Cyclosporine |
The androgen, Testosterone, may increase the hepatotoxicity of Cyclosporine. Testosterone may also elevate serum concentrations of Cyclosporine. Consider alternate therapy or monitor for signs of renal and hepatic toxicity. |
| Warfarin |
The androgen, Testosterone, may incrase the anticoagulant effect of the Vitamin K antagonist, Warfarin. Monitor for changes in the therapeutic effect of Warfarin if Testosterone is initiated, discontinued or dose changed. |
|
| Food Interactions |
Not Available
|
| Pathways |
Not Available
|
| General References |
Not Available |
| Organisms Affected |
|
