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Identification
NameECGONINE METHYL ESTER
Accession NumberDB04688
TypeSmall Molecule
GroupsExperimental
DescriptionNot Available
Structure
Thumb
SynonymsNot Available
External Identifiers Not Available
Approved Prescription ProductsNot Available
Approved Generic Prescription ProductsNot Available
Approved Over the Counter ProductsNot Available
Unapproved/Other Products Not Available
International BrandsNot Available
Brand mixturesNot Available
SaltsNot Available
Categories
UNIIY35FJB3QBJ
CAS numberNot Available
WeightAverage: 199.2469
Monoisotopic: 199.120843415
Chemical FormulaC10H17NO3
InChI KeyInChIKey=QIQNNBXHAYSQRY-UYXSQOIJSA-N
InChI
InChI=1S/C10H17NO3/c1-11-6-3-4-7(11)9(8(12)5-6)10(13)14-2/h6-9,12H,3-5H2,1-2H3/t6-,7+,8-,9+/m0/s1
IUPAC Name
methyl (1R,2R,3S,5S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
SMILES
[H][C@@]12CC[C@@]([H])(N1C)[C@@]([H])(C(=O)OC)[C@@]([H])(O)C2
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as tropane alkaloids. These are organic compounds containing the nitrogenous bicyclic alkaloid parent N-Methyl-8-azabicyclo[3.2.1]octane.
KingdomOrganic compounds
Super ClassAlkaloids and derivatives
ClassTropane alkaloids
Sub ClassNot Available
Direct ParentTropane alkaloids
Alternative Parents
Substituents
  • Tropane alkaloid
  • Piperidinecarboxylic acid
  • Beta-hydroxy acid
  • N-alkylpyrrolidine
  • Piperidine
  • Hydroxy acid
  • Methyl ester
  • Pyrrolidine
  • Cyclic alcohol
  • Tertiary aliphatic amine
  • Tertiary amine
  • Secondary alcohol
  • Carboxylic acid ester
  • Azacycle
  • Organoheterocyclic compound
  • Monocarboxylic acid or derivatives
  • Carboxylic acid derivative
  • Hydrocarbon derivative
  • Organooxygen compound
  • Organonitrogen compound
  • Carbonyl group
  • Amine
  • Alcohol
  • Aliphatic heteropolycyclic compound
Molecular FrameworkAliphatic heteropolycyclic compounds
External Descriptors
Pharmacology
IndicationNot Available
PharmacodynamicsNot Available
Mechanism of actionNot Available
Related Articles
AbsorptionNot Available
Volume of distributionNot Available
Protein bindingNot Available
MetabolismNot Available
Route of eliminationNot Available
Half lifeNot Available
ClearanceNot Available
ToxicityNot Available
Affected organismsNot Available
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.7991
Blood Brain Barrier+0.8824
Caco-2 permeable+0.748
P-glycoprotein substrateNon-substrate0.5304
P-glycoprotein inhibitor INon-inhibitor0.5359
P-glycoprotein inhibitor IINon-inhibitor0.9815
Renal organic cation transporterNon-inhibitor0.5248
CYP450 2C9 substrateNon-substrate0.7808
CYP450 2D6 substrateNon-substrate0.7909
CYP450 3A4 substrateSubstrate0.6138
CYP450 1A2 substrateNon-inhibitor0.8409
CYP450 2C9 inhibitorNon-inhibitor0.9527
CYP450 2D6 inhibitorNon-inhibitor0.8729
CYP450 2C19 inhibitorNon-inhibitor0.9477
CYP450 3A4 inhibitorNon-inhibitor0.9848
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9855
Ames testNon AMES toxic0.754
CarcinogenicityNon-carcinogens0.9624
BiodegradationReady biodegradable0.5936
Rat acute toxicity2.6061 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9177
hERG inhibition (predictor II)Non-inhibitor0.9158
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
ManufacturersNot Available
PackagersNot Available
Dosage formsNot Available
PricesNot Available
PatentsNot Available
Properties
StateSolid
Experimental PropertiesNot Available
Predicted Properties
PropertyValueSource
Water Solubility587.0 mg/mLALOGPS
logP0.14ALOGPS
logP-0.21ChemAxon
logS0.47ALOGPS
pKa (Strongest Acidic)14.6ChemAxon
pKa (Strongest Basic)9.04ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area49.77 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity51.34 m3·mol-1ChemAxon
Polarizability21.05 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, NegativeNot Available
References
Synthesis ReferenceNot Available
General ReferencesNot Available
External Links
ATC CodesNot Available
AHFS CodesNot Available
PDB EntriesNot Available
FDA labelNot Available
MSDSNot Available
Interactions
Drug Interactions
Drug
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with ECGONINE METHYL ESTER.
AcepromazineThe risk or severity of adverse effects can be increased when Acepromazine is combined with ECGONINE METHYL ESTER.
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with ECGONINE METHYL ESTER.
adipiplonThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with adipiplon.
AgomelatineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Agomelatine.
AlfaxaloneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Alfaxalone.
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with ECGONINE METHYL ESTER.
AlphacetylmethadolThe risk or severity of adverse effects can be increased when Alphacetylmethadol is combined with ECGONINE METHYL ESTER.
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with ECGONINE METHYL ESTER.
AmisulprideThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Amisulpride.
AmitriptylineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Amitriptyline.
AmobarbitalThe risk or severity of adverse effects can be increased when Amobarbital is combined with ECGONINE METHYL ESTER.
AmoxapineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Amoxapine.
AmperozideThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Amperozide.
AripiprazoleThe risk or severity of adverse effects can be increased when Aripiprazole is combined with ECGONINE METHYL ESTER.
ArticaineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Articaine.
AsenapineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Asenapine.
AzaperoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Azaperone.
AzelastineECGONINE METHYL ESTER may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
AzelastineThe risk or severity of adverse effects can be increased when Azelastine is combined with ECGONINE METHYL ESTER.
BaclofenThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Baclofen.
BarbitalThe risk or severity of adverse effects can be increased when Barbital is combined with ECGONINE METHYL ESTER.
BenzocaineThe risk or severity of adverse effects can be increased when Benzocaine is combined with ECGONINE METHYL ESTER.
Benzyl alcoholThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Benzyl alcohol.
BrexpiprazoleThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Brexpiprazole.
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of ECGONINE METHYL ESTER.
BrimonidineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Brimonidine.
BromazepamThe risk or severity of adverse effects can be increased when Bromazepam is combined with ECGONINE METHYL ESTER.
BrompheniramineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Brompheniramine.
BrotizolamThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Brotizolam.
BupivacaineThe risk or severity of adverse effects can be increased when Bupivacaine is combined with ECGONINE METHYL ESTER.
BuprenorphineThe risk or severity of adverse effects can be increased when Buprenorphine is combined with ECGONINE METHYL ESTER.
BuspironeThe risk or severity of adverse effects can be increased when Buspirone is combined with ECGONINE METHYL ESTER.
ButabarbitalThe risk or severity of adverse effects can be increased when Butabarbital is combined with ECGONINE METHYL ESTER.
ButacaineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Butacaine.
ButalbitalThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Butalbital.
ButambenThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Butamben.
ButethalThe risk or severity of adverse effects can be increased when Butethal is combined with ECGONINE METHYL ESTER.
ButorphanolThe risk or severity of adverse effects can be increased when Butorphanol is combined with ECGONINE METHYL ESTER.
CarbamazepineThe risk or severity of adverse effects can be increased when Carbamazepine is combined with ECGONINE METHYL ESTER.
CarbinoxamineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Carbinoxamine.
CarfentanilThe risk or severity of adverse effects can be increased when Carfentanil is combined with ECGONINE METHYL ESTER.
CarisoprodolThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Carisoprodol.
CetirizineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Cetirizine.
Chloral hydrateThe risk or severity of adverse effects can be increased when Chloral hydrate is combined with ECGONINE METHYL ESTER.
ChlordiazepoxideThe risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with ECGONINE METHYL ESTER.
ChlormezanoneThe risk or severity of adverse effects can be increased when Chlormezanone is combined with ECGONINE METHYL ESTER.
ChloroprocaineThe risk or severity of adverse effects can be increased when Chloroprocaine is combined with ECGONINE METHYL ESTER.
ChlorphenamineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Chlorphenamine.
ChlorpromazineThe risk or severity of adverse effects can be increased when Chlorpromazine is combined with ECGONINE METHYL ESTER.
ChlorprothixeneThe risk or severity of adverse effects can be increased when Chlorprothixene is combined with ECGONINE METHYL ESTER.
ChlorzoxazoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Chlorzoxazone.
CinchocaineThe risk or severity of adverse effects can be increased when Cinchocaine is combined with ECGONINE METHYL ESTER.
CitalopramThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Citalopram.
ClemastineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Clemastine.
ClidiniumThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Clidinium.
ClobazamThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Clobazam.
clomethiazoleThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with clomethiazole.
ClomipramineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Clomipramine.
ClonazepamThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Clonazepam.
ClonidineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Clonidine.
ClorazepateThe risk or severity of adverse effects can be increased when Clorazepate is combined with ECGONINE METHYL ESTER.
ClozapineThe risk or severity of adverse effects can be increased when Clozapine is combined with ECGONINE METHYL ESTER.
CocaineThe risk or severity of adverse effects can be increased when Cocaine is combined with ECGONINE METHYL ESTER.
CodeineThe risk or severity of adverse effects can be increased when Codeine is combined with ECGONINE METHYL ESTER.
CyclizineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Cyclizine.
CyclobenzaprineThe risk or severity of adverse effects can be increased when Cyclobenzaprine is combined with ECGONINE METHYL ESTER.
CyproheptadineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Cyproheptadine.
DantroleneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Dantrolene.
DapiprazoleThe risk or severity of adverse effects can be increased when Dapiprazole is combined with ECGONINE METHYL ESTER.
DapoxetineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Dapoxetine.
deramciclaneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with deramciclane.
DesfluraneThe risk or severity of adverse effects can be increased when Desflurane is combined with ECGONINE METHYL ESTER.
DesipramineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Desipramine.
DesloratadineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Desloratadine.
DetomidineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Detomidine.
DexbrompheniramineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Dexbrompheniramine.
DexmedetomidineThe risk or severity of adverse effects can be increased when Dexmedetomidine is combined with ECGONINE METHYL ESTER.
DextromoramideThe risk or severity of adverse effects can be increased when Dextromoramide is combined with ECGONINE METHYL ESTER.
DextropropoxypheneThe risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with ECGONINE METHYL ESTER.
DezocineThe risk or severity of adverse effects can be increased when Dezocine is combined with ECGONINE METHYL ESTER.
DiazepamThe risk or severity of adverse effects can be increased when Diazepam is combined with ECGONINE METHYL ESTER.
DifenoxinThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Difenoxin.
DihydrocodeineThe risk or severity of adverse effects can be increased when Dihydrocodeine is combined with ECGONINE METHYL ESTER.
DihydroetorphineThe risk or severity of adverse effects can be increased when Dihydroetorphine is combined with ECGONINE METHYL ESTER.
DihydromorphineThe risk or severity of adverse effects can be increased when Dihydromorphine is combined with ECGONINE METHYL ESTER.
DimenhydrinateThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Dimenhydrinate.
DiphenhydramineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with ECGONINE METHYL ESTER.
DiphenoxylateThe risk or severity of adverse effects can be increased when Diphenoxylate is combined with ECGONINE METHYL ESTER.
DoramectinThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Doramectin.
DoxepinThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Doxepin.
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of ECGONINE METHYL ESTER.
DoxylamineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Doxylamine.
DPDPEThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with DPDPE.
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of ECGONINE METHYL ESTER.
DroperidolThe risk or severity of adverse effects can be increased when Droperidol is combined with ECGONINE METHYL ESTER.
DrotebanolThe risk or severity of adverse effects can be increased when Drotebanol is combined with ECGONINE METHYL ESTER.
DyclonineThe risk or severity of adverse effects can be increased when Dyclonine is combined with ECGONINE METHYL ESTER.
EcgonineThe risk or severity of adverse effects can be increased when Ecgonine is combined with ECGONINE METHYL ESTER.
EfavirenzThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Efavirenz.
EnfluraneThe risk or severity of adverse effects can be increased when Enflurane is combined with ECGONINE METHYL ESTER.
EntacaponeThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Entacapone.
EscitalopramThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Escitalopram.
EstazolamThe risk or severity of adverse effects can be increased when Estazolam is combined with ECGONINE METHYL ESTER.
EszopicloneThe risk or severity of adverse effects can be increased when Eszopiclone is combined with ECGONINE METHYL ESTER.
EthanolECGONINE METHYL ESTER may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
EthanolThe risk or severity of adverse effects can be increased when Ethanol is combined with ECGONINE METHYL ESTER.
EthchlorvynolThe risk or severity of adverse effects can be increased when Ethchlorvynol is combined with ECGONINE METHYL ESTER.
EthosuximideThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Ethosuximide.
EthotoinThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Ethotoin.
Ethyl carbamateThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Ethyl carbamate.
Ethyl loflazepateThe risk or severity of adverse effects can be increased when Ethyl loflazepate is combined with ECGONINE METHYL ESTER.
EthylmorphineThe risk or severity of adverse effects can be increased when Ethylmorphine is combined with ECGONINE METHYL ESTER.
EtidocaineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Etidocaine.
EtifoxineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Etifoxine.
EtizolamThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Etizolam.
EtomidateThe risk or severity of adverse effects can be increased when Etomidate is combined with ECGONINE METHYL ESTER.
EtoperidoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Etoperidone.
EtorphineThe risk or severity of adverse effects can be increased when Etorphine is combined with ECGONINE METHYL ESTER.
EzogabineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Ezogabine.
FelbamateThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Felbamate.
FencamfamineThe risk or severity of adverse effects can be increased when Fencamfamine is combined with ECGONINE METHYL ESTER.
FenfluramineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Fenfluramine.
FentanylThe risk or severity of adverse effects can be increased when Fentanyl is combined with ECGONINE METHYL ESTER.
FexofenadineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Fexofenadine.
FlibanserinThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Flibanserin.
FludiazepamThe risk or severity of adverse effects can be increased when Fludiazepam is combined with ECGONINE METHYL ESTER.
FlunarizineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Flunarizine.
FlunitrazepamThe risk or severity of adverse effects can be increased when Flunitrazepam is combined with ECGONINE METHYL ESTER.
FluoxetineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Fluoxetine.
FlupentixolThe risk or severity of adverse effects can be increased when Flupentixol is combined with ECGONINE METHYL ESTER.
FluphenazineThe risk or severity of adverse effects can be increased when Fluphenazine is combined with ECGONINE METHYL ESTER.
FlurazepamThe risk or severity of adverse effects can be increased when Flurazepam is combined with ECGONINE METHYL ESTER.
FluspirileneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Fluspirilene.
Fluticasone PropionateThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Fluticasone Propionate.
FluvoxamineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Fluvoxamine.
FosphenytoinThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Fosphenytoin.
FospropofolThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Fospropofol.
GabapentinThe risk or severity of adverse effects can be increased when Gabapentin is combined with ECGONINE METHYL ESTER.
gabapentin enacarbilThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with gabapentin enacarbil.
Gamma Hydroxybutyric AcidThe risk or severity of adverse effects can be increased when Gamma Hydroxybutyric Acid is combined with ECGONINE METHYL ESTER.
GlutethimideThe risk or severity of adverse effects can be increased when Glutethimide is combined with ECGONINE METHYL ESTER.
GuanfacineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Guanfacine.
HalazepamThe risk or severity of adverse effects can be increased when Halazepam is combined with ECGONINE METHYL ESTER.
HaloperidolThe risk or severity of adverse effects can be increased when Haloperidol is combined with ECGONINE METHYL ESTER.
HalothaneThe risk or severity of adverse effects can be increased when Halothane is combined with ECGONINE METHYL ESTER.
HeroinThe risk or severity of adverse effects can be increased when Heroin is combined with ECGONINE METHYL ESTER.
HexobarbitalThe risk or severity of adverse effects can be increased when Hexobarbital is combined with ECGONINE METHYL ESTER.
HydrocodoneThe risk or severity of adverse effects can be increased when Hydrocodone is combined with ECGONINE METHYL ESTER.
HydromorphoneThe risk or severity of adverse effects can be increased when Hydromorphone is combined with ECGONINE METHYL ESTER.
HydroxyzineHydroxyzine may increase the central nervous system depressant (CNS depressant) activities of ECGONINE METHYL ESTER.
HydroxyzineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Hydroxyzine.
IloperidoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Iloperidone.
ImipramineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Imipramine.
IndalpineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Indalpine.
IsofluraneThe risk or severity of adverse effects can be increased when Isoflurane is combined with ECGONINE METHYL ESTER.
KetamineThe risk or severity of adverse effects can be increased when Ketamine is combined with ECGONINE METHYL ESTER.
KetazolamThe risk or severity of adverse effects can be increased when Ketazolam is combined with ECGONINE METHYL ESTER.
KetobemidoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Ketobemidone.
LamotrigineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Lamotrigine.
LevetiracetamThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Levetiracetam.
LevobupivacaineThe risk or severity of adverse effects can be increased when Levobupivacaine is combined with ECGONINE METHYL ESTER.
LevocabastineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Levocabastine.
LevocetirizineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Levocetirizine.
LevodopaThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Levodopa.
Levomethadyl AcetateThe risk or severity of adverse effects can be increased when Levomethadyl Acetate is combined with ECGONINE METHYL ESTER.
LevomilnacipranThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Levomilnacipran.
LevorphanolThe risk or severity of adverse effects can be increased when Levorphanol is combined with ECGONINE METHYL ESTER.
LidocaineThe risk or severity of adverse effects can be increased when Lidocaine is combined with ECGONINE METHYL ESTER.
LithiumThe risk or severity of adverse effects can be increased when Lithium is combined with ECGONINE METHYL ESTER.
LofentanilThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Lofentanil.
LoratadineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Loratadine.
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with ECGONINE METHYL ESTER.
LoxapineThe risk or severity of adverse effects can be increased when Loxapine is combined with ECGONINE METHYL ESTER.
Lu AA21004The risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Lu AA21004.
LurasidoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Lurasidone.
Magnesium SulfateMagnesium Sulfate may increase the central nervous system depressant (CNS depressant) activities of ECGONINE METHYL ESTER.
Magnesium SulfateThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Magnesium Sulfate.
MaprotilineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Maprotiline.
MeclizineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Meclizine.
MedetomidineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Medetomidine.
MelatoninThe risk or severity of adverse effects can be increased when Melatonin is combined with ECGONINE METHYL ESTER.
MelperoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Melperone.
MepivacaineThe risk or severity of adverse effects can be increased when Mepivacaine is combined with ECGONINE METHYL ESTER.
MeprobamateThe risk or severity of adverse effects can be increased when Meprobamate is combined with ECGONINE METHYL ESTER.
MesoridazineThe risk or severity of adverse effects can be increased when Mesoridazine is combined with ECGONINE METHYL ESTER.
MetaxaloneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Metaxalone.
MethadoneThe risk or severity of adverse effects can be increased when Methadone is combined with ECGONINE METHYL ESTER.
Methadyl AcetateThe risk or severity of adverse effects can be increased when Methadyl Acetate is combined with ECGONINE METHYL ESTER.
MethapyrileneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Methapyrilene.
MethaqualoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Methaqualone.
MethocarbamolThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Methocarbamol.
MethohexitalThe risk or severity of adverse effects can be increased when Methohexital is combined with ECGONINE METHYL ESTER.
MethotrimeprazineThe risk or severity of adverse effects can be increased when Methotrimeprazine is combined with ECGONINE METHYL ESTER.
MethoxyfluraneThe risk or severity of adverse effects can be increased when Methoxyflurane is combined with ECGONINE METHYL ESTER.
MethsuximideThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Methsuximide.
MethylphenobarbitalThe risk or severity of adverse effects can be increased when Methylphenobarbital is combined with ECGONINE METHYL ESTER.
MetyrosineECGONINE METHYL ESTER may increase the sedative activities of Metyrosine.
MidazolamThe risk or severity of adverse effects can be increased when Midazolam is combined with ECGONINE METHYL ESTER.
MilnacipranThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Milnacipran.
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of ECGONINE METHYL ESTER.
MirtazapineECGONINE METHYL ESTER may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
MirtazapineThe risk or severity of adverse effects can be increased when Mirtazapine is combined with ECGONINE METHYL ESTER.
MolindoneThe risk or severity of adverse effects can be increased when Molindone is combined with ECGONINE METHYL ESTER.
MorphineThe risk or severity of adverse effects can be increased when Morphine is combined with ECGONINE METHYL ESTER.
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of ECGONINE METHYL ESTER.
NabiloneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Nabilone.
NalbuphineThe risk or severity of adverse effects can be increased when Nalbuphine is combined with ECGONINE METHYL ESTER.
NitrazepamThe risk or severity of adverse effects can be increased when Nitrazepam is combined with ECGONINE METHYL ESTER.
Nitrous oxideThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Nitrous oxide.
NormethadoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Normethadone.
NortriptylineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Nortriptyline.
OlanzapineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Olanzapine.
OlopatadineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Olopatadine.
OndansetronThe risk or severity of adverse effects can be increased when Ondansetron is combined with ECGONINE METHYL ESTER.
OpiumThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Opium.
OrphenadrineECGONINE METHYL ESTER may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
OrphenadrineThe risk or severity of adverse effects can be increased when Orphenadrine is combined with ECGONINE METHYL ESTER.
OsanetantThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Osanetant.
OxazepamThe risk or severity of adverse effects can be increased when Oxazepam is combined with ECGONINE METHYL ESTER.
OxprenololThe risk or severity of adverse effects can be increased when Oxprenolol is combined with ECGONINE METHYL ESTER.
OxybuprocaineThe risk or severity of adverse effects can be increased when Oxybuprocaine is combined with ECGONINE METHYL ESTER.
OxycodoneThe risk or severity of adverse effects can be increased when Oxycodone is combined with ECGONINE METHYL ESTER.
OxymorphoneThe risk or severity of adverse effects can be increased when Oxymorphone is combined with ECGONINE METHYL ESTER.
PaliperidoneThe risk or severity of adverse effects can be increased when Paliperidone is combined with ECGONINE METHYL ESTER.
ParaldehydeECGONINE METHYL ESTER may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
ParaldehydeThe risk or severity of adverse effects can be increased when Paraldehyde is combined with ECGONINE METHYL ESTER.
ParoxetineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Paroxetine.
PentazocineThe risk or severity of adverse effects can be increased when Pentazocine is combined with ECGONINE METHYL ESTER.
PentobarbitalThe risk or severity of adverse effects can be increased when Pentobarbital is combined with ECGONINE METHYL ESTER.
PerampanelThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Perampanel.
PerospironeThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Perospirone.
PerphenazineThe risk or severity of adverse effects can be increased when Perphenazine is combined with ECGONINE METHYL ESTER.
PethidineThe risk or severity of adverse effects can be increased when Pethidine is combined with ECGONINE METHYL ESTER.
PhenobarbitalThe risk or severity of adverse effects can be increased when Phenobarbital is combined with ECGONINE METHYL ESTER.
PhenoxyethanolThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Phenoxyethanol.
PhenytoinThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Phenytoin.
PimozideThe risk or severity of adverse effects can be increased when Pimozide is combined with ECGONINE METHYL ESTER.
PipamperoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Pipamperone.
PipotiazineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Pipotiazine.
PizotifenThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Pizotifen.
PomalidomideThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Pomalidomide.
PramipexoleECGONINE METHYL ESTER may increase the sedative activities of Pramipexole.
PramocaineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Pramocaine.
PrazepamThe risk or severity of adverse effects can be increased when Prazepam is combined with ECGONINE METHYL ESTER.
PregabalinThe risk or severity of adverse effects can be increased when Pregabalin is combined with ECGONINE METHYL ESTER.
PrilocaineThe risk or severity of adverse effects can be increased when Prilocaine is combined with ECGONINE METHYL ESTER.
PrimidoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Primidone.
ProcaineThe risk or severity of adverse effects can be increased when Procaine is combined with ECGONINE METHYL ESTER.
ProchlorperazineThe risk or severity of adverse effects can be increased when Prochlorperazine is combined with ECGONINE METHYL ESTER.
PromazineThe risk or severity of adverse effects can be increased when Promazine is combined with ECGONINE METHYL ESTER.
PromethazineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Promethazine.
ProparacaineThe risk or severity of adverse effects can be increased when Proparacaine is combined with ECGONINE METHYL ESTER.
PropofolThe risk or severity of adverse effects can be increased when Propofol is combined with ECGONINE METHYL ESTER.
PropoxycaineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Propoxycaine.
ProtriptylineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Protriptyline.
PSD502The risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with PSD502.
QuazepamThe risk or severity of adverse effects can be increased when Quazepam is combined with ECGONINE METHYL ESTER.
QuetiapineThe risk or severity of adverse effects can be increased when Quetiapine is combined with ECGONINE METHYL ESTER.
RamelteonThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Ramelteon.
RemifentanilThe risk or severity of adverse effects can be increased when Remifentanil is combined with ECGONINE METHYL ESTER.
RemoxiprideThe risk or severity of adverse effects can be increased when Remoxipride is combined with ECGONINE METHYL ESTER.
ReserpineThe risk or severity of adverse effects can be increased when Reserpine is combined with ECGONINE METHYL ESTER.
RisperidoneThe risk or severity of adverse effects can be increased when Risperidone is combined with ECGONINE METHYL ESTER.
RomifidineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Romifidine.
RopiniroleECGONINE METHYL ESTER may increase the sedative activities of Ropinirole.
RopivacaineThe risk or severity of adverse effects can be increased when Ropivacaine is combined with ECGONINE METHYL ESTER.
RotigotineECGONINE METHYL ESTER may increase the sedative activities of Rotigotine.
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with ECGONINE METHYL ESTER.
S-EthylisothioureaThe risk or severity of adverse effects can be increased when S-Ethylisothiourea is combined with ECGONINE METHYL ESTER.
ScopolamineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Scopolamine.
SecobarbitalThe risk or severity of adverse effects can be increased when Secobarbital is combined with ECGONINE METHYL ESTER.
SertindoleThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Sertindole.
SertralineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Sertraline.
SevofluraneThe risk or severity of adverse effects can be increased when Sevoflurane is combined with ECGONINE METHYL ESTER.
Sodium oxybateThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Sodium oxybate.
StiripentolThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Stiripentol.
SufentanilThe risk or severity of adverse effects can be increased when Sufentanil is combined with ECGONINE METHYL ESTER.
SulpirideThe risk or severity of adverse effects can be increased when Sulpiride is combined with ECGONINE METHYL ESTER.
SuvorexantThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Suvorexant.
TapentadolThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Tapentadol.
TasimelteonThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Tasimelteon.
TemazepamThe risk or severity of adverse effects can be increased when Temazepam is combined with ECGONINE METHYL ESTER.
TetrabenazineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Tetrabenazine.
TetracaineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Tetracaine.
TetrodotoxinThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Tetrodotoxin.
ThalidomideECGONINE METHYL ESTER may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
ThalidomideThe risk or severity of adverse effects can be increased when Thalidomide is combined with ECGONINE METHYL ESTER.
ThiamylalThe risk or severity of adverse effects can be increased when Thiamylal is combined with ECGONINE METHYL ESTER.
ThiopentalThe risk or severity of adverse effects can be increased when Thiopental is combined with ECGONINE METHYL ESTER.
ThioridazineThe risk or severity of adverse effects can be increased when Thioridazine is combined with ECGONINE METHYL ESTER.
ThiothixeneThe risk or severity of adverse effects can be increased when Thiothixene is combined with ECGONINE METHYL ESTER.
TiagabineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Tiagabine.
TiletamineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Tiletamine.
TizanidineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Tizanidine.
TolcaponeThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Tolcapone.
TopiramateThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Topiramate.
TramadolThe risk or severity of adverse effects can be increased when Tramadol is combined with ECGONINE METHYL ESTER.
Trans-2-PhenylcyclopropylamineThe risk or severity of adverse effects can be increased when Trans-2-Phenylcyclopropylamine is combined with ECGONINE METHYL ESTER.
TranylcypromineThe risk or severity of adverse effects can be increased when Tranylcypromine is combined with ECGONINE METHYL ESTER.
TrazodoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Trazodone.
TriazolamThe risk or severity of adverse effects can be increased when Triazolam is combined with ECGONINE METHYL ESTER.
TrifluoperazineThe risk or severity of adverse effects can be increased when Trifluoperazine is combined with ECGONINE METHYL ESTER.
TriflupromazineThe risk or severity of adverse effects can be increased when Triflupromazine is combined with ECGONINE METHYL ESTER.
TrimipramineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Trimipramine.
TriprolidineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Triprolidine.
Valproic AcidThe risk or severity of adverse effects can be increased when Valproic Acid is combined with ECGONINE METHYL ESTER.
VigabatrinThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Vigabatrin.
VilazodoneThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Vilazodone.
VortioxetineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Vortioxetine.
XylazineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Xylazine.
ZaleplonThe risk or severity of adverse effects can be increased when Zaleplon is combined with ECGONINE METHYL ESTER.
ZiconotideThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Ziconotide.
ZimelidineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Zimelidine.
ZiprasidoneThe risk or severity of adverse effects can be increased when Ziprasidone is combined with ECGONINE METHYL ESTER.
ZolazepamThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Zolazepam.
ZolpidemThe risk or severity of adverse effects can be increased when Zolpidem is combined with ECGONINE METHYL ESTER.
ZonisamideThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Zonisamide.
ZopicloneThe risk or severity of adverse effects can be increased when Zopiclone is combined with ECGONINE METHYL ESTER.
ZotepineThe risk or severity of adverse effects can be increased when ECGONINE METHYL ESTER is combined with Zotepine.
ZuclopenthixolThe risk or severity of adverse effects can be increased when Zuclopenthixol is combined with ECGONINE METHYL ESTER.
Food InteractionsNot Available

Targets

Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Immunoglobulin receptor binding
Specific Function:
Not Available
Gene Name:
IGHG2
Uniprot ID:
P01859
Molecular Weight:
35900.445 Da
References
  1. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [PubMed:10592235 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Immunoglobulin receptor binding
Specific Function:
Not Available
Gene Name:
IGKC
Uniprot ID:
P01834
Molecular Weight:
11608.765 Da
References
  1. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [PubMed:10592235 ]
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Drug created on September 11, 2007 11:49 / Updated on August 17, 2016 12:24