Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen

Identification

Summary

Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is a component of a live attenuated influenza vaccine.

Brand Names
FluMist Quadrivalent
Generic Name
Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen
DrugBank Accession Number
DB18661
Background

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in an immunological defense against future exposure to the virus, or "antigen". This defense includes the production of humoral immunity through the development of antibodies and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to an influenza virus, the immune system is prepared with circulating antibodies that identify and destroy the virus.

There are three basic types of vaccines available: inactivated influenza vaccine (IIV), live attenuated influenza vaccine (LAIV), and recombinant influenza vaccines (RIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde. Inactivated viruses cannot replicate and thus cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability. Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes.

Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Attenuated
Synonyms
Not Available

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
Acetylsalicylic acidThe risk or severity of Reye's syndrome can be increased when Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is combined with Acetylsalicylic acid.
Aminosalicylic acidThe risk or severity of Reye's syndrome can be increased when Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is combined with Aminosalicylic acid.
BalsalazideThe risk or severity of Reye's syndrome can be increased when Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is combined with Balsalazide.
Bismuth subsalicylateThe risk or severity of Reye's syndrome can be increased when Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is combined with Bismuth subsalicylate.
Choline salicylateThe risk or severity of Reye's syndrome can be increased when Influenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen is combined with Choline salicylate.
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
FluMist QuadrivalentInfluenza A virus A/Norway/31694/2022 (H1N1) live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza A virus A/Norway/16606/2021 (H3N2) live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza B virus B/Austria/1359417/2021 live (attenuated) antigen (10000000 [FFU]/0.2mL) + Influenza B virus B/Phuket/3073/2013 live (attenuated) antigen (10000000 [FFU]/0.2mL)SprayNasalMedImmune, LLC2023-08-14Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Not Available
CAS number
Not Available

References

General References
Not Available
RxNav
2645084

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SprayNasal
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at October 10, 2023 20:29 / Updated at October 11, 2023 10:34