Displaying drugs 701 - 725 of 754 in total
Exagamglogene autotemcel
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats …
Matched Description: … hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and ... [A262691] Treatment options for SCD are largely focused on preventing the production and circulation ... of HbS and inducing the production of normal fetal hemoglobin (HbF),[A262696,A262701] including [hydroxyurea …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and ... [A262691] Treatment options for SCD are largely focused on preventing the production and circulation ... of HbS and inducing the production of normal fetal hemoglobin (HbF),[A262696,A262701] including [hydroxyurea …
Matched Categories: … Blood and Blood Forming Organs …
Bethanechol
Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary.[A232905,L32539] For example, bethanechol is readily used to treat postoperative or...
Approved
Matched International brands: … Uro-Carb …
Matched Description: … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function ... to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system …
Matched Description: … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function ... to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system …
NKG2D-ACE2 CAR-NK Cell
These cells are prepared as universal off-the-shelf CAR-NK cells from cord blood with NKG2D-ACE2 proteins engineered as part of the CARs; the cell secretes IL-15 and GM-CSF. Chimeric antigen receptors (CARs) are artificial receptors consisting of an antibody-derived antigen binding domain and transmembrane and signaling domains from T-cell receptor signalling...
Investigational
Matched Synonyms: … ACE2 CAR-NK Cell ... NKG2D CAR-NK Cell ... ACE2 CAR-Natural Killer Cell …
Matched Name: … NKG2D-ACE2 CAR-NK Cell …
Matched Description: … engineered as part of the CARs; the cell secretes IL-15 and GM-CSF. ... The GM-CSF acts as a neutralizer for the CAR-T cell-mediated cytokine release and neurotoxicity. ... binding domain and transmembrane and signaling domains from T-cell receptor signalling moieties. …
Matched Name: … NKG2D-ACE2 CAR-NK Cell …
Matched Description: … engineered as part of the CARs; the cell secretes IL-15 and GM-CSF. ... The GM-CSF acts as a neutralizer for the CAR-T cell-mediated cytokine release and neurotoxicity. ... binding domain and transmembrane and signaling domains from T-cell receptor signalling moieties. …
C-CAR039
C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
Investigational
Matched Synonyms: … an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR …
Matched Description: … CAR. ... C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific …
Matched Description: … CAR. ... C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific …
Botaretigene sparoparvovec
Investigational
Matched Synonyms: … PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUS ADENO-ASSOCIATED VIRUS 2 INVERTED TERMINAL REPEAT …
Antithrombin gamma
Antithrombin gamma is under investigation in clinical trial NCT04182373 (KW-3357 Study in Patients With Early Onset Severe Preeclampsia).
Investigational
Matched Synonyms: … Human antithrombin-iii (atiii, serpin c1) expressed in fucosyl transferase-negative chinese hamster ovary …
Chlorpheniramine
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. ... One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and …
Matched Mixtures name: … ANDIS OBP ANAK ... Ana-kit ... Care One Cold and Allergy …
Matched Products: … Chlor-tripolon Night Time Allergy Relief …
Matched Mixtures name: … ANDIS OBP ANAK ... Ana-kit ... Care One Cold and Allergy …
Matched Products: … Chlor-tripolon Night Time Allergy Relief …
Atorvastatin
Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched International brands: … Cardyl …
Matched Description: … lipid levels, and ultimately reduce the risk of cardiovascular disease. ... Bruce Roth and approved by the FDA in 1996. ... inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine and atorvastatin ... Amlodipine and atorvastatin …
Matched Categories: … atorvastatin and ezetimibe ... atorvastatin and amlodipine ... atorvastatin and perindopril ... atorvastatin, amlodipine and ramipril ... atorvastatin and acetylsalicylic acid …
Matched Products: … ATORVASTATINA P-CARE ... CARDYN 10 MG FILM TABLET, 30 ADET ... CARDYN 10 MG FILM TABLET, 90 ADET …
Matched Description: … lipid levels, and ultimately reduce the risk of cardiovascular disease. ... Bruce Roth and approved by the FDA in 1996. ... inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine and atorvastatin ... Amlodipine and atorvastatin …
Matched Categories: … atorvastatin and ezetimibe ... atorvastatin and amlodipine ... atorvastatin and perindopril ... atorvastatin, amlodipine and ramipril ... atorvastatin and acetylsalicylic acid …
Matched Products: … ATORVASTATINA P-CARE ... CARDYN 10 MG FILM TABLET, 30 ADET ... CARDYN 10 MG FILM TABLET, 90 ADET …
Diethyltoluamide
Diethyltoluamide (DEET) is the common active ingredient in many insect repellent products. It is widely used to repel biting pests such as mosquitoes and ticks. Every year, DEET formulations are used to protect populations from mosquito-borne illnesses like West Nile Virus, the Zika virus, malaria, and/or tick-borne illnesses like Lyme...
Approved
Matched International brands: … Repel …
Matched Description: … It is widely used to repel biting pests such as mosquitoes and ticks. ... /or tick-borne illnesses like Lyme disease and Rocky Mountain spotted fever. ... to protect populations from mosquito-borne illnesses like West Nile Virus, the Zika virus, malaria, and …
Matched Categories: … Benzamides and benzamide derivatives ... Antiparasitic Products, Insecticides and Repellents ... Insecticides and Repellents ... Scabicides, Insecticides and Repellents …
Matched Description: … It is widely used to repel biting pests such as mosquitoes and ticks. ... /or tick-borne illnesses like Lyme disease and Rocky Mountain spotted fever. ... to protect populations from mosquito-borne illnesses like West Nile Virus, the Zika virus, malaria, and …
Matched Categories: … Benzamides and benzamide derivatives ... Antiparasitic Products, Insecticides and Repellents ... Insecticides and Repellents ... Scabicides, Insecticides and Repellents …
Anti-CD5 CAR T-cell therapy
Investigational
Matched Synonyms: … anti-CD5 CAR T cells ... chimeric antigen receptor (CAR) directed against the target protein CD5 …
Matched Name: … Anti-CD5 CAR T-cell therapy …
Matched Name: … Anti-CD5 CAR T-cell therapy …
Epidermal Growth Factor Receptor variant III (EGFRvIII) chimeric antigen receptor T cells
Investigational
Matched Synonyms: … EGFRvIII CAR-T ... Autologous Chimeric Antigen Receptor (CAR) Modified Recombinant T Cells Targeting EGFRvIII …
SynKIR-110
SynKIR-110 are autologous T cells genetically engineered to express an anti-mesothelin killer immunoglobulin-like receptor-chimeric antigen receptor (KIR-CAR).
Investigational
Matched Synonyms: … SynKIR-meso CAR-T cells …
Matched Description: … engineered to express an anti-mesothelin killer immunoglobulin-like receptor-chimeric antigen receptor (KIR-CAR …
Matched Description: … engineered to express an anti-mesothelin killer immunoglobulin-like receptor-chimeric antigen receptor (KIR-CAR …
Epirubicin
An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Description: … The compound exerts its antitumor effects by interference with the synthesis and function of DNA. …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … EPIRUBICINA CARLO ERBA …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … EPIRUBICINA CARLO ERBA …
UCART22
UCART22 are allogeneic CD22-specific universal CAR-expressing T lymphocytes.
Investigational
Matched Synonyms: … Allogeneic gene-edited CAR T cells UCART22 ... Allogeneic TALEN gene-edited CAR T-Cells UCART22 ... Allogenic engineered T cells expressing anti-CD22 CAR UCART22 …
Matched Description: … UCART22 are allogeneic CD22-specific universal CAR-expressing T lymphocytes. …
Matched Description: … UCART22 are allogeneic CD22-specific universal CAR-expressing T lymphocytes. …
Carbamazepine
Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1....
Approved
Investigational
Matched Description: … and to treat pain resulting from trigeminal neuralgia. ... Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures …
Matched Products: … CARBA - CT 200MG TABLETTEN …
Matched Products: … CARBA - CT 200MG TABLETTEN …
Reveglucosidase alfa
Investigational
Matched Synonyms: … glycyl-l-alanyl-l-prolyl-human lysosomal alpha-glucosidase (acid maltase, aglucosidase alfa) produced in chinese hamster ovary …
Piracetam
Piracetam is a nootropic drug in the racetams group, with chemical name 2-oxo-1-pyrrolidine acetamide. It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative of the neurotransmitter γ-aminobutyric acid (GABA). However its mechanism of action differ from that of endogenous GABA. Piracetam has neuroprotective and...
Approved
Investigational
Matched Description: … Piracetam has neuroprotective and anticonvulsant properties and is reported to improve neural plasticity ... It shares the same 2-oxo-pyrrolidone base structure with pyroglutamic acid and is a cyclic derivative ... Its efficacy is documented in cognitive disorders and dementia, vertigo, cortical myoclonus, dyslexia …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … FLAVIS …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … FLAVIS …
PBCAR20A
Investigational
Matched Synonyms: … Allogeneic anti-CD20 CAR T cells ... Allogeneic gene edited CD20-directed CAR (Chimeric Antigen Receptor) T cells …
CAR BCMA-CS1
CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target B-cell maturation antigen and CS1.
Investigational
Matched Name: … CAR BCMA-CS1 …
Matched Description: … B-cell maturation antigen and CS1. ... CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target …
Matched Description: … B-cell maturation antigen and CS1. ... CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target …
Diltiazem
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched International brands: … Cartia …
Matched Description: … FDA-approved indications, diltiazem has also been used for numerous off-label indications, such as anal ... Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Calcium-Regulating Hormones and Agents …
Matched Products: … Cartia XT ... Cartia Xt …
Matched Description: … FDA-approved indications, diltiazem has also been used for numerous off-label indications, such as anal ... Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Calcium-Regulating Hormones and Agents …
Matched Products: … Cartia XT ... Cartia Xt …
Ciltacabtagene autoleucel
Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000, and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience a range of symptoms including...
Approved
Investigational
Matched Synonyms: … Autologous bi-epitope BCMA-targeted CAR T-cells …
Matched Description: … It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000,[L40749] and is ... asymptomatic, while others may experience a range of symptoms including bone pain, hematologic abnormalities, and ... [A245854] While normally expressed on plasma blasts and plasma cells, BCMA is widely expressed on malignant …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Antineoplastic cell and gene therapy …
Matched Description: … It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000,[L40749] and is ... asymptomatic, while others may experience a range of symptoms including bone pain, hematologic abnormalities, and ... [A245854] While normally expressed on plasma blasts and plasma cells, BCMA is widely expressed on malignant …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Antineoplastic cell and gene therapy …
B7-H3-specific chimeric antigen receptor T cells
Investigational
Matched Synonyms: … Autologous chimeric antigen receptor (CAR) T cells targeting B7-H3 ... chimeric antigen receptor (CAR) modified recombinant T cells targeting B7-H3 ... allogeneic T cells genetically modified to express anti-B7-H3 chimeric antigen receptor (CAR) …
OriCar-017
Investigational
Matched Synonyms: … GPRC5D-CAR-T ... chimeric antigen receptor (CAR)-T cell therapy targeting G protein-coupled receptor class-C group-5 member-D …
Displaying drugs 701 - 725 of 754 in total