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Displaying drugs 76 - 100 of 2774 in total

Moroctocog alfa

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Synonyms: … Human factor VIII, recombinant B-domain deleted ... Antihemphilic factor, recombinant human B-domain deleted …
Matched Description: … purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... amino acid, 170 kDa protein [FDA Label]. ... Moroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …

Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Human Antihemophilic Factors …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … enhanced secretion of bile acids and lipids in the feces, patients who take complicated medication regimens ... Bile acid sequestrants like colestipol have been in use since the 1970s. ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated …
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity …

Camphor

Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA...
Approved
Withdrawn
Matched Description: … It is used topically as a skin antipruritic and as an anti-infective agent. ... When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often ... The FDA ruled that camphorated oil could not be marketed in the United States and that no product could …
Matched Mixtures name: … Jack and Jill Rub ... Dermoplex Bite and Sting Cream ... OFF Bite and Itch Relief First Aid Antiseptic …
Matched Categories: … Basic Lotions and Liniments ... Antipruritics and Local Anesthetics …
Matched Products: … HUMCO Camphor Spirit ... Muscle and Joint HRX Pain Relieving ... Joints and Muscles Pain Relieving …

Smallpox and Monkeypox Vaccine, Live, Non-replicating

Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …

Talquetamab

Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … ) (HUMAN MONOCLONAL JNJ-63483043 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL JNJ-63483043 .LAMBDA ... -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC …
Matched Description: … arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

OTL-102

OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. It is being investigated for the treatment of X-linked chronic granulomatous disease.
Investigational
Matched Synonyms: … Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced ... ex vivo using a lentiviral vector encoding the human gp91phox gene …
Matched Description: … OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells ... transduced ex vivo using a lentiviral vector encoding the human gp91phox gene. …

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … receptors in the pituitary gland and blocks interaction with GnRH. ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately ... are D-amino acids. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Gonadotropin-releasing Hormone Antagonists ... Gonadotropin Releasing Hormone Receptor Antagonists …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Hypothalamic Hormones ... Sex Hormones and Insulins ... Somatostatin and Analogues …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... Signifor LAR 20mg powder and solvent for suspension for injection …

Lonoctocog alfa

Approved
Investigational
Matched Products: … AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL ... AFSTYLA 250IU powder and solvent for solution for injection …

Aluminum zirconium octachlorohydrex gly

Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Description: … It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. ... Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and ... Interestingly, this chemical has been studied in relation to its possible impact on the microbiome of the human …
Matched Mixtures name: … Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN …
Matched Products: … Suave IS Sweet Pea and Violet Antiperspirant and Deodorant ... Axe Touch Antiperspirant and Deodorant ... Suave Cocoa Butter Antiperspirant and Deodorant …

Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It was also approved by FDA and EMA in 2016. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …

Rurioctocog alfa pegol

Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia A to manage and ... Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …

DCVAC/OvCa

DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …

CHF5633

CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Phosphatidic Acids …

Zenocutuzumab

Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and …
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

VOR33

VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …

Taniraleucel

Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, ... Allogeneic natural killer (NK) cells derived from CD34+ human placental stem/progenitor cells. …

Petrolatum

A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Description: … It is used as an ointment base, topical protectant, and lubricant. …
Matched Mixtures name: … Humana Pharmacy Hemorrhoidal ... A and D Diaper Rash and Skin Protectant ... PETROLATUM and LANOLIN …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Procurevitamin A and D Vitamin A and D ... A and D ... Vitamin A and D …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Name: … Coagulation factor VIIa Recombinant Human …
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form ... NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. ... Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Products: … NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... powder and solvent for solution for injection 2mg ... powder and solvent for solution for injection 1mg …

Ergidina

Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic …
Matched Description: … Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif. …

Naproxen

Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched Synonyms: … (+)-2-(6-Methoxy-2-naphthyl)propionic acid ... (+)-2-(Methoxy-2-naphthyl)-propionic acid ... (S)-2-(6-Methoxy-2-naphthyl)propanoic acid …
Matched Iupac: … (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid …
Matched Description: … prescription use in 1976 and then for over-the-counter (OTC) use in 1994. ... Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for ... [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has …
Matched Mixtures name: … Up and Up Sinus and Cold D ... Sinus and Cold D ... Sinus and Cold D …
Matched Categories: … Naphthaleneacetic Acids ... Arylpropionic acid NSAIDS ... naproxen and misoprostol ... naproxen and esomeprazole ... Antiinflammatory and Antirheumatic Products …
Matched Products: … NAPROXEN ACIS 500MG ... Naprosyn Sus 25mg/ml ... Humana Pharmacy All Day Pain Relief …

Coagulation Factor IX (Recombinant)

Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX recombinant human …
Matched Description: … It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, ... It is not derived from human blood (unlike human Factor IX complex), and is instead produced by a genetically ... and has structural and functional characteristics similar to those of endogenous factor IX. …
Matched Products: … BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 250iu/vial ... BeneFIX Powder and Solvent for Solution for Injection 1000iu/vial …

Acetaminophen

Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Description: … of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines ... tablets, injection, suppository, and other forms. ... Acetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and …
Matched Mixtures name: … Humana Pharmacy Daytime Cold and Flu Relief ... Humana Pharmacy Sinus Relief ... Acetaminophen, Ascorbic acid, Chlorpheniramine Maleate …
Matched Categories: … Acetaminophen and Prodrugs ... codeine and paracetamol ... tramadol and paracetamol ... oxycodone and paracetamol ... dihydrocodeine and paracetamol …
Matched Products: … Children's Tylenol Sus 160mg/5ml Liq-grape ... Infant's Tylenol Sus 80mg/ml Dps - Grape Fl ... Pain and Fever …

Lansoprazole

Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies...
Approved
Investigational
Matched Description: … [A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective ... Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally ... at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along …
Matched Mixtures name: … Lansoprazole, Amoxicillin, and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin …
Matched Categories: … Acid Reducers ... Alimentary Tract and Metabolism ... Gastric Acid Lowering Agents ... lansoprazole, amoxicillin and levofloxacin ... Drugs for Acid Related Disorders …
Matched Products: … Foster and Thrive Acid Reducer ... Up and Up Lansoprazole ... Berkley and Jensen Lansoprazole …
Displaying drugs 76 - 100 of 2774 in total