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Displaying drugs 101 - 125 of 11636 in total

Disperse Blue 106

Disperse Blue 106 is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … 5-Nitro-2-(2-methyl-4-(N-ethyl-N-(2-hydroxyethyl)amino)phenylazo)thiazole …
Matched Iupac: … 2-[ethyl({3-methyl-4-[(E)-2-(5-nitro-1,3-thiazol-2-yl)diazen-1-yl]phenyl})amino]ethan-1-ol …

Gadobutrol

Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Synonyms: … gadolinium(III) 2,2',2''-(10-((2R,3S )-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7 …
Matched Iupac: … 4,7,10-tris(carboxymethyl)-1-[(2S,3R)-1,3,4-trihydroxybutan-2-yl]-1,4,7,10-tetraaza-13-gadolinatetracyclo …
Matched Description: … gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 …

Phentolamine

Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral doses of phentolamine.[A261781, A261786] It has several therapeutic uses, including...
Approved
Matched Synonyms: … 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline ... 3-((4,5-DIHYDRO-1H-IMIDAZOL-2-YLMETHYL)(4-METHYLPHENYL)AMINO)PHENOL …
Matched Iupac: … 3-{[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino}phenol …

Esmolol

Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Synonyms: … (±)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate ... methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate ... Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate …
Matched Iupac: … methyl 3-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)propanoate …

Flucloxacillin

Antibiotic analog of cloxacillin.
Approved
Investigational
Matched Synonyms: … -4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... 3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin ... (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo …
Matched Iupac: … [3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Salts cas: … 34214-51-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Flucloxacillin WABO 2 g Pulver zur Herstellung einer Injektions-/Infusionslösung …

Ertapenem

Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem ... ene-2-carboxylic acid ... carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2- …
Matched Iupac: … ene-2-carboxylic acid ... )carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Glimepiride

First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Iupac: … 3-ethyl-4-methyl-2-oxo-N-(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)- …
Matched Description: … Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by ... Sulfonylureas are one of the insulin secretagogues widely used for the management of type 2 diabetes ... glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 …
Matched Mixtures name: … DUERID 30/2 MG TABLET, 90 ADET ... DUERID 30/4 MG TABLET, 90 ADET ... GLUCOVEL 2 …
Matched Products: … TIDECA 2 MG TABLET, TABLET, 90 ADET ... GLIRID 2 MG ÇENTİKLİ TABLET, 90 ADET ... AMARYL 6 MG TABLET, 90 ADET …

Chlormerodrin

Chlormerodrin is a mercurial compound with toxic side effects that was previously used as a diuretic. The radiolabeled form has been used as a diagnostic and research tool. It is no longer used and has been replaced with new classes of diuretic drugs.
Approved
Withdrawn
Matched Synonyms: … 1-[3-(chloromercuri)-2-methoxypropyl]urea ... {3-[(aminocarbonyl)amino]-2-methoxypropyl}chloromercury …
Matched Iupac: … [3-(chloromercurio)-2-methoxypropyl]urea …

Eflornithine

Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … 2-(difluoromethyl)ornithine ... (RS)-2,5-diamino-2-(difluoromethyl)pentanoic acid …
Matched Iupac: … 2,5-diamino-2-(difluoromethyl)pentanoic acid …

Tetradecyl hydrogen sulfate (ester)

Sodium tetradecyl sulfate is an anionic surface-active agent which is used for its wetting properties in the industry and is also used in medicine as a blood vessel irritant and sclerosing agent for hemorrhoids and varicose veins . Sodium tetradecyl sulfate has been widely used since the 1950s, and in...
Approved
Matched Synonyms: … 7-Ethyl-2-methyl-4-undecanol sulfate …
Matched Iupac: … [(7-ethyl-2-methylundecan-4-yl)oxy]sulfonic acid …

Saxagliptin

Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Matched Synonyms: … (1S,3S,5S)-2-((2S)-Amino(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrile …
Matched Iupac: … (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile …

Ibrutinib

Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Synonyms: … 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Iupac: … 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … IMBRUVICA 140 MG SERT KAPSÜL ,90 KAPSÜL …

Sofosbuvir

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Synonyms: … -methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoate ... S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4 …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … a prodrug nucleotide analog, Sofosbuvir is metabolized into its active form as the antiviral agent 2' ... -deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective …
Matched Mixtures name: … HARVONI 90 MG/400 MG FILM KAPLI TABLET, 84 ADET ... HARVONI 90 MG/400 MG FILM KAPLI TABLET, 28 ADET …

Denileukin diftitox

A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system.
Approved
Investigational
Matched Synonyms: … Interleukin-2/diptheria toxin fusion protein …
Matched Description: … (IL-2; Ala 1-Thr 133). ... for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 …

Melatonin

Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … N-[2-(5-methoxyindol-3-yl)ethyl]acetamide …
Matched Iupac: … N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Mellozzan 2 mg Tabletten ... CIRCADIN 2 MG PROLONGED-RELEASE TABLETS ... Melatonin Bluefish 2 mg Retardtabletten …

Domperidone

A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Synonyms: … -2-one ... 5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone ... 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2 …
Matched Iupac: … -benzodiazol-2-one ... 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Methoxyphenamine

Approved
Matched Synonyms: … 2-Methoxymethamphetamine …
Matched Iupac: … [1-(2-methoxyphenyl)propan-2-yl](methyl)amine …

Didanosine

A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral...
Approved
Matched Synonyms: … 9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ol ... 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one ... 9-((2R,5S)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one …
Matched Iupac: … 9-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Tapentadol

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Synonyms: … 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol ... PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)- …
Matched Iupac: … 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol …

Solriamfetol

Solriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated with narcolepsy or obstructive sleep apnea[FDA Label]. Solriamfetol was given FDA approval in 2019[FDA Label].
Approved
Matched Synonyms: … (2R)-2-amino-3-phenylpropyl carbamate …
Matched Iupac: … (2R)-2-amino-3-phenylpropyl carbamate …

Ethionamide

A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Approved
Matched Synonyms: … 2-ethyl-4-thiopyridylamide ... 2-ethylthioisonicotinamide …
Matched Iupac: … 2-ethylpyridine-4-carbothioamide …

Technetium Tc-99m mebrofenin

Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it...
Approved
Matched Synonyms: … Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetium …
Matched Iupac: … 2-({[(3-bromo-2,4,6-trimethylphenyl)carbamoyl]methyl}(carboxymethyl)amino)acetic acid technetium …

Metolazone

A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Synonyms: … 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide ... 2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone ... 7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide …
Matched Iupac: … 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

L-Lactic acid

Approved
Experimental
Matched Synonyms: … (S)-2-hydroxypropanoic acid ... (S)-2-hydroxypropionic acid …
Matched Iupac: … (2S)-2-hydroxypropanoic acid …
Matched Mixtures name: … Prismasol 2 …

Hydroxyethyl cellulose

Hydroxyethyl cellulose is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and stabilizing properties. It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. It is often used as an ingredient in ophthalmic pharmaceutical preparations such as...
Approved
Matched Synonyms: … 2-Hydroxyethyl cellulose ether …
Matched Iupac: … 1-{[3,4,5-tris(2-hydroxypropoxy)-6-{[4,5,6-tris(2-hydroxypropoxy)-2-[(2-hydroxypropoxy)methyl]oxan-3- ... yl]oxy}oxan-2-yl]methoxy}propan-2-ol …
Matched Salts name: … Hydroxyethyl cellulose (100 MPa.s at 2%) ... Hydroxyethyl cellulose (1800 MPa.s at 2%) ... Hydroxyethyl cellulose (280 MPa.s at 2%) ... Hydroxyethyl cellulose (40 MPa.s at 2%) ... Hydroxyethyl cellulose (5500 MPa.s at 2%) …
Displaying drugs 101 - 125 of 11636 in total