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Displaying drugs 201 - 225 of 10509 in total
Linaclotide is a synthetic 14-amino acid cyclic peptide and first-in-class guanylate cyclase-C (G-CC) agonist.[A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C. It is also a homolog of a heat-stable enterotoxin derived from Escherichia coli, the first natural ligand...
Approved
Matched Synonyms: … GLUTAMYL-L-TYROSYL-L-CYSTEINYL-L-CYSTEINYL-L-ASPARAGINYL-L-PROLYL-L-ALANYL-L-CYSTEINYL-L-THREONYLGLYCYL-L-CYSTEINYL-, CYCLIC (1- …
Matched Iupac: … ,7S,13S,16R,21R,24R,27S,30S,33R,38R,44S)-21-amino-13-(carbamoylmethyl)-27-(2-carboxyethyl)-44-[(1R)-1- …
Approved
Matched Synonyms: … Phosphoric acid, sodium salt (1:2) …
Matched Salts cas: … 118830-14-1
Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Approved
Matched Synonyms: … Phosphoric acid, potassium salt (1:2) …
A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1- …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... FLUORETS STERILE OPHTHALMIC STRIP 1 mg ... FLUSİBLE 500 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
A sulfanilamide that is used as an antibacterial agent.
Approved
Vet approved
Matched Synonyms: … N(1)-(4-Methyl-2-pyrimidinyl)sulfanilamide …
Matched Iupac: … 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide …
A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile. Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Synonyms: … 6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.02,7.012,16]hexadeca-1( …
Matched Iupac: … diazatricyclo[7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1( …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin...
Approved
Matched Iupac: … 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-4H,6H,7H,8H,9H-pyrido[ …
Matched Description: … Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic …
Matched Salts cas: … 199739-10-1
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … XEPLION 100 MG/1 ML IM ENJEKSİYON İÇİN UZUN SALIMLI SÜSPANSİYON, 1 ADET ... XEPLION 50 MG/0,5 ML IM ENJEKSİYON İÇİN UZUN SALIMLI SÜSPANSİYON, 1 ADET ... XEPLION 150 MG/1,5 ML IM ENJEKSİYON İÇİN UZUN SALIMLI SÜSPANSİYON, 1 ADET …
Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … Antisense Oligonucleotide Inhibitor Of The Expression Of Superoxide Dismutase 1 Gene …
A chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.
Approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Intal Nebulizer 1% ... EYECROL %4 GÖZ DAMLASI, 1 ADET ... Novo-cromolyn Nebulizer Solution 1% …
D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis . Cholestasis is the reduction or stoppage of bile flow, either to impaired secretion by hepatocytes (liver cells) or obstruction , . Tocofersolan is a...
Approved
Matched Synonyms: … .-(4-((3,4-DIHYDRO-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-2H-1-BENZOPYRAN-6-YL)OXY)-1,4-DIOXOBUTYL …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Originally approved by the FDA in 1959 [FDA label], carisoprodol is a centrally acting muscle relaxant used in painful musculoskeletal conditions in conjunction with physical therapy and other medications . This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with...
Approved
Matched Synonyms: … (1-methylethyl)carbamic acid 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl ester …
Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110α , which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological processes, including proliferation, survival, differentiation, and metabolism. Alpelisib was designed to target...
Approved
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result of beta decay, approximately 10% of...
Approved
Investigational
Matched Products: … IOKAM BHR I-131 ORAL KAPSÜL ,1 ADET ... IOKAM BHR I-131 ORAL ÇÖZELTI ,1 ADET ... MON.IYOT-131 74-18500 MBQ ORAL ÇÖZELTİ İÇEREN FLAKON, 1 MCİ …
Rifamycin is the prime member of the rifamycin family which are represented by drugs that are a product of fermentation from the gram-positive bacterium Amycolatopsis mediterranei, also known as Streptomyces mediterranei. The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence...
Approved
Investigational
Matched Mixtures name: … RIF 125 MG 1 AMPUL ... RIF 250 MG 1 AMPUL ... RIFETEM 250 MG / 3 ML AMPUL, 1 ADET …
Matched Categories: … MATE 1 Inhibitors …
Matched Products: … RIFOCINA�SPRAY 1% ... RIFOCINA®SPRAY 1% ... RIFAMICINA 1% SPRAY …
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has...
Approved
Investigational
Withdrawn
Matched Mixtures name: … EMULİD PLUS % 1 + % 5 JEL ... ETNA COMBO %1 / %0.25 JEL ... NIMOKAIN %1 + %5 JEL, 50 G …
Matched Products: … NIMEKSIL %1 JEL ,1 TÜP ... NIMELID %1 JEL, 20 G ... EMULID %1 JEL, 30 G …
Sodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added. It contains radioactive fluoride F 18 that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging and is administered by intravenous injection. Its primary indication is for bone imaging. Increased deposition around joints can...
Approved
Matched Products: … MON.NAF (18F) 250 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency. It has a long duration of action as it is usually taken once daily. Solifenacin was granted FDA approval on 19 November 2004.
Approved
Matched Iupac: … (3R)-1-azabicyclo[2.2.2]octan-3-yl (1S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate …
Matched Products: … Vesicare 1 mg/ml Suspension zum Einnehmen …
Anthralin (1,8‐dihydroxy‐9anthrone, dithranol) is an older anti-psoriatic agent that was first synthesized as a derivative of chrysarobin, obtained from the araroba tree in Brazil over 100 years ago. Adverse effects of anthralin include irritation and discoloration of the skin . This specific property of the molecule inspired workers to study...
Approved
Matched Products: … Anthraforte 1 Ointment 1% …
Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions . Infliximab is produced by a recombinant cell line cultured by continuous perfusion. Tumor necrosis factor-alpha (TNF-α) is a key proinflammatory cytokine involved in...
Approved
Matched Products: … INFUZYON COZELTISI HAZIRLAMAK ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET ... AVSOLA 100 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ, 1 ADET ... REMICADE 100 MG KONSANTRE IV INFUZYON COZELTISI HAZIRLAMAK ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …
Silver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree burns.
Approved
Vet approved
Matched Iupac: … silver(1+) 4-{[(pyrimidin-2-yl)azanidyl]sulfonyl}aniline …
Matched Mixtures name: … SİLVERDİN PLUS %1 + %5 KREM, 50 G …
Matched Products: … DYFAZINE CREAM 1% ... Dermazin Crm 1% ... SULFAPLATA 1% CREMA …
Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate...
Approved
Investigational
Matched Products: … VINARIX 1 MG/1 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... VINCREST 1 MG / 1 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... VINCRISTINA 1 MG POR 1 FRASCO …
Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Iupac: … (2S)-2-{[(1R)-1-carbamoylethyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}-3-methylbutyl]-2 ... (2R)-6-{[bis(ethylamino)methylidene]amino}-N-[(1S)-1-{[(2S)-6-{[bis(ethylamino)methylidene]amino}-1-[ …
Matched Products: … ORGALUTRAN 0,25 MG/0,5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ORGALUTRAN 0,25 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports...
Approved
Withdrawn
Matched Products: … Kwellada Lotion 1% ... PMS-lindane Shp 1% ... PMS-lindane Lot 1% …
Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS). It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells that express the CD20 antigen. Compared to non-humanized CD20 antibodies such as rituximab, ocrelizumab is...
Approved
Investigational
Matched Products: … OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Displaying drugs 201 - 225 of 10509 in total