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Displaying drugs 76 - 100 of 470 in total

Mepolizumab

Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm3 or more) is associated with a spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and hypereosinophilic syndrome (HES). The pathogenesis of eosinophilia is complex, but IL-5 is recognized as...
Approved
Investigational
Matched Description: … Activated eosinophils further stimulate an inflammatory response and also induce tissue lesions and promote ... Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically ... spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML ... NUCALA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/ML …

Dulaglutide

Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and ... [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for ... use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Trulicity 1.5mg solution for injection in pre-filled pen ... Trulicity 0.75mg solution for injection in pre-filled pen …

Ofatumumab

Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing ... [A6921] Ofatumumab is available for intravenous administration and is marketed as Arzerra. ... IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML ... Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringe ... KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 20MG/0.4ML …

Hepatitis B immune globulin

Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. According to the Centers for Disease Control...
Approved
Investigational
Matched Description: … The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. ... During the process, viruses are deactivated, and in the final steps, solvents used in the preparation ... According to the Centers for Disease Control and Prevention (CDC), the hepatitis B vaccine was the first …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … HyperHEP B S/D Pre-filled Syringe 1mL ... HyperHEP B S/D Pre-filled Syringe 0.5mL ... Niuliva Solution For Infusion In Pre-Filled Syringe 600 I.U./2.4 ml …

Hydrogen peroxide

Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it may undergo potentially explosive thermal decomposition....
Approved
Vet approved
Matched Description: … whites, and dried egg yolks. ... cheese products, and as an oxidizing and reducing agent in products containing dried eggs, dried egg ... and gas form for preservative, disinfection and sterilization applications as an oxidative biocide [A32369 …
Matched Mixtures name: … Royal Whitening Pre-Brush ... Prevention Wound and Burn ... QCare Oral Cleansing and Suctioning System, Q4 …
Matched Categories: … Alimentary Tract and Metabolism ... Antiseptics and Disinfectants ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Preop ... Preop Rinse ... Hydrogen Peroxide Top Sol 3% 10vol Anti …

Tinzaparin

Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. Tinzaparin is composed of molecules with and without a special site for high affinity binding...
Approved
Matched Description: … It is an anticoagulant and considered an antithrombotic. ... It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. ... Tinzaparin is composed of molecules with and without a special site for high affinity binding to antithrombin …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … INNOHEP 14,000 ANTIXA IU/0.7ML (pre-filled syringes) ... INNOHEP INYECTABLE JERINGA PRE-LLENADA 3500 UI/0.35 ML ... INNOHEP INYECTABLE JERINGA PRE-LLENADA 2500 UI/0.25/ML. …

Glucagon

Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643] Glucagon was granted FDA...
Approved
Matched Description: … diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and ... Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Gvoke PFS 1 mg Pre-filled Syringe ... Gvoke PFS 0.5 mg Pre-filled Syringe …

Magnesium sulfate

A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … treatment of pre-eclampsia and eclampsia. ... Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. ... A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the …
Matched Mixtures name: … Sodium Sulfate, Potassium Sulfate, and Magnesium Sulfate Bowel Prep kit ... SUPREP Bowel Prep ... SUPREP Bowel Prep …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Calcium-Regulating Hormones and Agents ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Spearmint and Menthol scented Natural Epsom Salt ... PRE-EKLAMOL MAGNEZYUM SÜLFAT 40 G/1000 ML IV İNFÜZYON İÇİN ÇÖZELTİ ... PRE-EKLAMOL MAGNEZYUM SÜLFAT 4 G/100 ML I.V. İNFÜZYON İÇİN ÇÖZELTİ , 100 ML …

Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen

Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and …

Respiratory syncytial virus vaccine, adjuvanted

Arexvy (respiratory syncytial virus vaccine, adjuvanted) is an adjuvanted vaccine developed by GlaxoSmithKline Biologicals. It comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized in pre-fusion conformation as the antigen component, which is reconstituted at the time of use with the accompanying vial of AS01E adjuvant as the adjuvant...
Approved
Matched Synonyms: … RECOMBINANT RESPIRATORY SYNCYTIAL VIRUS PRE-FUSION F PROTEIN …
Matched Description: … comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized in pre-fusion …

EDIT-301

EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2).
Investigational
Matched Synonyms: … Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 ... ) at the HBG1 and HBG2 promoters ... autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP …
Matched Description: … cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2). ... EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …

Lixisenatide

Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide …
Matched Products: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG (50mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MCG (100mcg/mL) …

Dupilumab

Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … immunological reactions in several atopic or allergic conditions, such as eczema, allergic reaction, and ... dermatitis, asthma as an add-on maintenance treatment, chronic rhinosinusitis with nasal polyposis, and ... inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents …
Matched Products: … Dupixent 300 mg Solution for Injection in Pre-filled Syringe ... Dupixent 200mg Solution for Injection in Pre-Filled Syringe ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml …

Benzylpenicilloyl polylysine

Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy. The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects.
Approved
Matched Products: … Pre-pen …

Romosozumab

Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924]. ... antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and ... Romosozumab prevents bone resorption and induces the formation of bone though it is associated with an …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML ... EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML …

ALX-009

Investigational
Matched Synonyms: … Hypothiocyanite and lactoferrin …

Secukinumab

Secukinumab is a fully human monoclonal IgG1/κ antibody against interleukin-17A (IL-17A), a proinflammatory cytokine implicated in various chronic immune-mediated inflammatory disorders, such as plaque psoriasis. By blocking the actions of IL-17A, secukinumab works to inhibit the pro-inflammatory pathways that drive immune-mediated inflammatory disorders. Following its first global approval in Japan...
Approved
Matched Description: … in Japan in December 2014, secukinumab was approved by the European Commission on January 15, 2015, and ... chronic inflammatory conditions, such as plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Cosentyx 150mg/ml solution for injection in pre-filled syringe ... Fraizeron 150mg/ml solution for injection in pre-filled pen ... COSENTYX SOLUTION FOR INJECTION IN PRE-FILLED UNOREADY PEN 300MG/2ML …

TA-CIN

TA-CIN is a subunit vaccine comprising L2/E6/E7 proteins from Human Papillomavirus (HPV16), designed to generate a strong cellular immune response against HPV-infected cells.
Investigational
Matched Name: … TA-CIN …
Matched Description: … TA-CIN is a subunit vaccine comprising L2/E6/E7 proteins from Human Papillomavirus (HPV16), designed …

Fremanezumab

Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for the prevention of migraine headaches. It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. Along with other recently approved anti-CGRP therapies such as galcanezumab, erenumab, and the oral CGRP antagonist...
Approved
Investigational
Matched Description: … [L11749] It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. ... [L11779] Along with other recently approved anti-CGRP therapies such as [galcanezumab], [erenumab], and ... oral CGRP antagonist [ubrogepant], fremanezumab represents an important step forward in the treatment and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5ML …

SP1049C

SP1049C is a novel anthracycline chemotherapeutic agent containing doxorubicin and two nonionic pluronic block copolymers. It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review. Preliminary data, in its first clinically tested indication,...
Investigational
Matched Synonyms: … doxorubicin with pluronics F-127 and L-61 ... Doxorubicin HCl with pluronic L-61 and pluronic F-127 …
Matched Description: … Median survival is encouraging and correlates strongly with dose levels.[A260416] ... SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic …

Semaglutide

Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.[A31421,L8681] Other members of this drug class include Exenatide and Liraglutide. Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection...
Approved
Investigational
Matched Description: … and reducing blood glucose. ... [A31421,L8681] Other members of this drug class include [Exenatide] and [Liraglutide]. ... 1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … OZEMPIC 1MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML ... OZEMPIC 0.25MG, 0.5MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML ... Ozempic® 1.34 mg/ml (1 mg/dose) Solution for injection in pre-filled pen …

Insulin glargine

Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … and proteolysis. ... tissues such as the liver, fat cells, and skeletal muscle. ... addition of two arginines to the C-terminus (positions B31 and 32) of the B-chain. …
Matched Mixtures name: … Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 33MCG/ML …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … LANTUS SOLOSTAR 100IU/ML SOLUTION FOR INJECTION IN A PRE-FILLED PEN ... Glaritus 100IU/mL Solution for injection in Pre-filled Pen ... Toujeo 300 units/ml Solution for Injection in Pre-Filled Pen …

Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated)

Approved
Matched Products: … IXIARO Suspension for Injection 0.5ml in pre-filled syringe …

Ritodrine

Adrenergic beta-agonist used to control premature labor.
Approved
Investigational
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … PRE-PAR 50 MG/5 ML IM/IV ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL …

Inclisiran

Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density lipoprotein cholesterol (LDL-C) levels. By binding to PCSK9 messenger RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and plasma...
Approved
Investigational
Matched Description: … RNA, inclisiran prevents protein translation of PCSK9, leading to decreased concentrations of PCSK9 and ... 11, 2020, the European Commission (EC) granted authorization for marketing inclisiran as the first and ... plasma LDL-C levels offers an additional benefit of reducing the risk of cardiovascular disease (CVD) and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Sybrava 284mg/1.5ml Solution for Injection in Pre-filled Syringe …
Displaying drugs 76 - 100 of 470 in total