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Displaying drugs 126 - 150 of 705 in total
Reteplase
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... delete certain portions of human tPA. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... delete certain portions of human tPA. …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Colestipol
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces, patients ... of its pharmacological activity sometimes limits its usefulness. ... be good candidates for using the agent owing to its physical effects on the gut. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces, patients ... of its pharmacological activity sometimes limits its usefulness. ... be good candidates for using the agent owing to its physical effects on the gut. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Turoctocog alfa
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any human- or animal-derived ... rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …
Lidocaine
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched Description: … Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an ... , hypotension, and irregular heart rate, among others [F4349, L5930, L5948]. ... of tissues means the agent is indicated for facilitating local anesthesia for a large variety of surgical …
Matched Mixtures name: … CVS Health Cold and Hot Roll-On ... FAK Care4 Bus and School Yellow ORM D ... FAK Care4 Bus and School Yellow ORM D …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Analgesics and Anesthetics ... Antipruritics and Local Anesthetics …
Matched Products: … QC Cool and Heat Roll-On ... Omeza Licodaine Pain and Itch Relief Oil ... Foster and Thrive …
Matched Mixtures name: … CVS Health Cold and Hot Roll-On ... FAK Care4 Bus and School Yellow ORM D ... FAK Care4 Bus and School Yellow ORM D …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Analgesics and Anesthetics ... Antipruritics and Local Anesthetics …
Matched Products: … QC Cool and Heat Roll-On ... Omeza Licodaine Pain and Itch Relief Oil ... Foster and Thrive …
Aluminum chlorohydrate
Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Description: … 3n-m)(OH)m. ... The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which ... Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl( …
Matched Mixtures name: … Watkins Roll On Deodorant ... Anti-perspirant Roll-ON Deod ... Ban Ultra Antiperspirant Roll-ON …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Astringents and Deodorants ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Hi and Dri Roll On ... G and H Protect Deodorant and Antiperspirant Roll On ... Suave Powder Roll On Antiperspirant and Deodorant …
Matched Mixtures name: … Watkins Roll On Deodorant ... Anti-perspirant Roll-ON Deod ... Ban Ultra Antiperspirant Roll-ON …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Astringents and Deodorants ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Hi and Dri Roll On ... G and H Protect Deodorant and Antiperspirant Roll On ... Suave Powder Roll On Antiperspirant and Deodorant …
Ethylmorphine
A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and...
Experimental
Illicit
Matched Synonyms: … 3-O-Ethylmorphine …
Matched Iupac: … -7(18),8,10,15-tetraen-14-ol ... (1S,5R,13R,14S,17R)-10-ethoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function ... A narcotic analgesic and antitussive. ... In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products). …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... Heterocyclic Compounds with 4 or More Rings ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Iupac: … -7(18),8,10,15-tetraen-14-ol ... (1S,5R,13R,14S,17R)-10-ethoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function ... A narcotic analgesic and antitussive. ... In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products). …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... Heterocyclic Compounds with 4 or More Rings ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide
Experimental
Matched Synonyms: … D-pyridoxyl-N,O-cycloserylamide-5-monophosphate …
Matched Name: … D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide …
Matched Iupac: … {[5-hydroxy-6-methyl-4-({[(4R)-3-oxo-1,2-oxazolidin-4-yl]amino}methyl)pyridin-3-yl]methoxy}phosphonic …
Matched Name: … D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide …
Matched Iupac: … {[5-hydroxy-6-methyl-4-({[(4R)-3-oxo-1,2-oxazolidin-4-yl]amino}methyl)pyridin-3-yl]methoxy}phosphonic …
5'-O-(L-Cysteinylsulfamoyl)adenosine
Experimental
Matched Synonyms: … 5'-O-(N-(L-Cysteinyl)-sulfamoyl)adenosine …
Matched Name: … 5'-O-(L-Cysteinylsulfamoyl)adenosine …
Matched Iupac: … 4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-sulfanylpropan-1-one …
Matched Name: … 5'-O-(L-Cysteinylsulfamoyl)adenosine …
Matched Iupac: … 4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-sulfanylpropan-1-one …
Allolactose
Experimental
Matched Synonyms: … 6-O-β-D-galactopyranosyl-D-glucopyranose …
Matched Iupac: … (3R,4S,5S,6R)-6-({[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxane-2,3,4,5 …
Matched Iupac: … (3R,4S,5S,6R)-6-({[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxane-2,3,4,5 …
trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium(1-)
Experimental
Matched Synonyms: … N-methyl O-nitrophenyl aminoethyldiphosphate beryllium trifluoride …
Matched Name: … trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium …
Matched Iupac: … ({hydroxy[(trifluoroberylliuide)oxy]phosphoryl}oxy)({2-[methyl(2-nitrophenyl)amino]ethoxy})phosphinic …
Matched Name: … trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium …
Matched Iupac: … ({hydroxy[(trifluoroberylliuide)oxy]phosphoryl}oxy)({2-[methyl(2-nitrophenyl)amino]ethoxy})phosphinic …
KRN-7000
KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With Hematological Malignancies Undergoing AHSCT.
Investigational
Matched Synonyms: … 1-O-(α-D-galactopyranosyl)-N-hexacosanoylphytosphingosine …
Matched Iupac: … N-[(2S,3S,4R)-3,4-dihydroxy-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}octadecan …
Matched Description: … B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With ... KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis …
Matched Iupac: … N-[(2S,3S,4R)-3,4-dihydroxy-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}octadecan …
Matched Description: … B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With ... KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis …
FET F-18
FET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of Recurrent GBM to Avastin).
Investigational
Matched Synonyms: … O-18F-fluoroethyl-L-tyrosine ... O-(2-FLUOROETHYL)-L-TYROSINE F-18 …
Matched Description: … FET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of …
Matched Description: … FET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of …
beta-D-Ribose-5-phosphate
Experimental
Matched Synonyms: … 5-O-phosphono-β-D-ribofuranose ... 5-O-phosphono-beta-D-ribofuranose …
Flubentylosin
Investigational
Matched Synonyms: … 4b-o-((4-fluorophenyl)methyl)tylosin ... Tylosin, 4b-o-((4-fluorophenyl)methyl)- …
Matched Iupac: … 6R)-4-(dimethylamino)-5-{[(2S,4R,5S,6S)-5-[(4-fluorophenyl)methoxy]-4-hydroxy-4,6-dimethyloxan-2-yl]oxy ... }-3-hydroxy-6-methyloxan-2-yl]oxy}-16-ethyl-4-hydroxy-15-({[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy- ... 6-methyloxan-2-yl]oxy}methyl)-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde …
Matched Iupac: … 6R)-4-(dimethylamino)-5-{[(2S,4R,5S,6S)-5-[(4-fluorophenyl)methoxy]-4-hydroxy-4,6-dimethyloxan-2-yl]oxy ... }-3-hydroxy-6-methyloxan-2-yl]oxy}-16-ethyl-4-hydroxy-15-({[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy- ... 6-methyloxan-2-yl]oxy}methyl)-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde …
3'-O-Acetylthymidine-5'-diphosphate
Experimental
Matched Synonyms: … 3'-O-Acetylthymidine 5'-(trihydrogen diphosphate) …
Matched Name: … 3'-O-Acetylthymidine-5'-diphosphate …
Matched Iupac: … acetyloxy)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Matched Name: … 3'-O-Acetylthymidine-5'-diphosphate …
Matched Iupac: … acetyloxy)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Cyproterone acetate
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Approved
Investigational
Matched Synonyms: … Cyproterone 17-O-acetate …
Matched Description: … in combination with estrogen, for the therapy of severe acne and hirsutism in females. ... It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, ... An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties …
Matched Mixtures name: … OC - 35 …
Matched Categories: … Sex Hormones and Modulators of the Genital System ... Antiandrogens and Estrogens ... cyproterone and estrogen ... Genito Urinary System and Sex Hormones ... Combination Contraceptives (with Estrogen and derivatives) …
Matched Products: … Andro - Diane 10 mg - Tabletten …
Matched Description: … in combination with estrogen, for the therapy of severe acne and hirsutism in females. ... It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, ... An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties …
Matched Mixtures name: … OC - 35 …
Matched Categories: … Sex Hormones and Modulators of the Genital System ... Antiandrogens and Estrogens ... cyproterone and estrogen ... Genito Urinary System and Sex Hormones ... Combination Contraceptives (with Estrogen and derivatives) …
Matched Products: … Andro - Diane 10 mg - Tabletten …
Romilkimab
Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational
Matched Synonyms: … Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13) …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in ... the Treatment of Idiopathic Pulmonary Fibrosis). …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in ... the Treatment of Idiopathic Pulmonary Fibrosis). …
Carbidopa
Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Description: … approved on 2014. ... It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and …
Matched Mixtures name: … LEVOCAENT OR 100/25/200 ... LEVOCAENT OR 100/25/200 ... LEVOCAENT OR 100/25/200 …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …
Matched Mixtures name: … LEVOCAENT OR 100/25/200 ... LEVOCAENT OR 100/25/200 ... LEVOCAENT OR 100/25/200 …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …
Daidzin
Experimental
Matched Synonyms: … Daidzein 7-O-glucoside ... daidzein 7-O-β-D-glucoside ... daidzein 7-O-beta-D-glucoside …
Matched Iupac: … 4-one ... 3-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen- …
Matched Iupac: … 4-one ... 3-(4-hydroxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen- …
Cyclouridine
Experimental
Matched Synonyms: … 2,2'-O-Cyclouridine …
Matched Iupac: … 4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-3,7-dioxa-1,9-diazatricyclo[6.4.0.0^{2,6}]dodeca-8,11-dien-10-one …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-3,7-dioxa-1,9-diazatricyclo[6.4.0.0^{2,6}]dodeca-8,11-dien-10-one …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Estradiol sulfamate
Investigational
Matched Synonyms: … Estradiol-3-O-Sulfamate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
DCVAC/OvCa
DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … It is under investigation for the treatment of ovarian cancer. ... DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …
Matched Description: … It is under investigation for the treatment of ovarian cancer. ... DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …
CHF5633
CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
O-acetyl-L-serine
Experimental
Matched Synonyms: … O3-acetyl-L-serine …
Matched Name: … O-acetyl-L-serine …
Matched Name: … O-acetyl-L-serine …
Displaying drugs 126 - 150 of 705 in total