Amphetamines

Analogs or derivatives of AMPHETAMINE. Many are sympathomimetics and central nervous system stimulators causing excitation, vasopressin, bronchodilation, and to varying degrees, anorexia, analepsis, nasal decongestion, and some smooth muscle relaxation.
DrugDrug NameDrug Indication
DB00852PseudoephedrineFor the treatment of nasal congestion, sinus congestion, Eustachian tube congestion, and vasomotor rhinitis, and as an adjunct to other agents in the optimum treatment of allergic rhinitis, croup, sinusitis, otitis media, and tracheobronchitis. Also used as first-line therapy of priapism.
DB00937DiethylpropionUsed in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
DB01255LisdexamfetamineFor the treatment of Attention Deficit/Hyperactivity Disorder (ADHD) in pediatric populations aged 6 to 12 years.
DB01576DextroamphetamineUsed to treat attention deficit hyperactivity disorder (ADHD).
DB00182AmphetamineFor treatment of Attention Deficit Disorder with Hyperactivity (ADDH), narcolepsy, and exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction for patients refractory to alternative therapy.
DB00191PhentermineFor the treatment and management of obesity.
DB00865BenzphetamineFor the management of exogenous obesity as a short term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction
DB01365MephentermineUsed to maintain blood pressure in hypotensive states.
DB01442MMDAMMDA is a recreational drug. It has no current medical uses and is a Schedule I controlled substance in the USA at present.
DB01454MidomafetamineClinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used illicit drugs in the U.S.
DB014672,5-Dimethoxy-4-ethylamphetamineNot Available
DB014844-Bromo-2,5-dimethoxyamphetamineNot Available
DB015093,4-MethylenedioxyamphetamineNot Available
DB01556ChlorphentermineUsed as an appetite suppressant.
DB01577MethamphetamineFor the treatment of Attention Deficit Disorder with Hyperactivity (ADHD) and exogenous obesity.
DB09352HydroxyamphetamineMydriatic agent (eye pupil dilatation) for diagnosis of ophthalmic nerve lesions.
DB12080RitobegronNot Available
DB13108MephedroneNot Available
DB13624MethoxyphenamineNot Available
DB139402,5-Dimethoxy-4-ethylthioamphetamineNot Available
DrugDrug NameTargetType
DB00852PseudoephedrineAmine oxidase [flavin-containing] Aenzyme
DB00852PseudoephedrineCytochrome P450 2D6enzyme
DB00852PseudoephedrineAlpha-1A adrenergic receptortarget
DB00852PseudoephedrineAlpha-2A adrenergic receptortarget
DB00852PseudoephedrineBeta-2 adrenergic receptortarget
DB00852PseudoephedrineBeta-1 adrenergic receptortarget
DB00852PseudoephedrineSodium-dependent dopamine transportertarget
DB00852PseudoephedrineSodium-dependent noradrenaline transportertarget
DB00852PseudoephedrineSodium-dependent serotonin transportertarget
DB00852PseudoephedrineNuclear factor of activated T-cells, cytoplasmic 1target
DB00852PseudoephedrineTumor necrosis factortarget
DB00852PseudoephedrineNuclear factor kappa-light-chain-enhancer of activated B cellstarget
DB00852Pseudoephedrineactivator protein 1target
DB00852PseudoephedrineInterleukin-2target
DB00937DiethylpropionSodium-dependent noradrenaline transportertarget
DB00937DiethylpropionSodium-dependent dopamine transportertarget
DB01255LisdexamfetamineAlpha-1B adrenergic receptortarget
DB01255LisdexamfetamineSodium-dependent dopamine transportertarget
DB01576DextroamphetamineAlpha-1A adrenergic receptortarget
DB01576DextroamphetamineAlpha-1B adrenergic receptortarget
DB01576DextroamphetamineSodium-dependent dopamine transportertarget
DB01576DextroamphetamineSodium-dependent noradrenaline transportertarget
DB01576DextroamphetamineSynaptic vesicular amine transportertarget
DB01576DextroamphetamineTrace amine-associated receptor 1target
DB00182AmphetamineCytochrome P450 2D6enzyme
DB00182AmphetamineCytochrome P450 2A6enzyme
DB00182AmphetamineSodium-dependent dopamine transportertarget
DB00182AmphetamineCocaine- and amphetamine-regulated transcript proteintarget
DB00182AmphetamineTrace amine-associated receptor 1target
DB00182AmphetamineSynaptic vesicular amine transportertarget
DB00182AmphetamineSodium-dependent noradrenaline transportertarget
DB00182AmphetamineAlpha adrenergic receptortarget
DB00182AmphetamineBeta adrenergic receptortarget
DB00182AmphetamineD(2) dopamine receptortarget
DB00182AmphetamineAmine oxidase [flavin-containing] Btarget
DB00182AmphetamineSodium-dependent serotonin transportertarget
DB00182AmphetamineMonoamine oxidasetarget
DB00182Amphetaminevesicular monoamine transporter 2 (VMAT2)target
DB00182AmphetamineSolute carrier family 22 member 3transporter
DB00182AmphetamineSolute carrier family 22 member 5transporter
DB00191PhentermineAmine oxidase [flavin-containing] Aenzyme
DB00191PhentermineAmine oxidase [flavin-containing] Benzyme
DB00191PhentermineCytochrome P450 1A2enzyme
DB00191PhentermineSodium-dependent noradrenaline transportertarget
DB00191PhentermineSodium-dependent dopamine transportertarget
DB00191PhentermineAmine oxidase [flavin-containing] Atarget
DB00191PhentermineAmine oxidase [flavin-containing] Btarget
DB00191PhentermineSodium-dependent serotonin transportertarget
DB00865BenzphetamineCytochrome P450 3A4enzyme
DB00865BenzphetamineCytochrome P450 2B6enzyme
DB00865BenzphetamineNADPH--cytochrome P450 reductaseenzyme
DB00865BenzphetamineAlpha-2A adrenergic receptortarget
DB00865BenzphetamineAlpha-1A adrenergic receptortarget
DB00865BenzphetamineSynaptic vesicular amine transportertarget
DB00865BenzphetamineSodium-dependent dopamine transportertarget
DB01365MephentermineAlpha adrenergic receptortarget
DB01365MephentermineBeta adrenergic receptortarget
DB01442MMDA5-hydroxytryptamine receptor 2Atarget
DB01442MMDASodium-dependent serotonin transportertarget
DB01442MMDASodium-dependent dopamine transportertarget
DB01442MMDAChromaffin granule amine transportertarget
DB01442MMDASynaptic vesicular amine transportertarget
DB01442MMDAAmine oxidase [flavin-containing] Atarget
DB01442MMDAAmine oxidase [flavin-containing] Btarget
DB01442MMDASodium-dependent noradrenaline transportertarget
DB01454MidomafetamineCytochrome P450 2D6enzyme
DB01454MidomafetamineSodium-dependent serotonin transportertarget
DB01454MidomafetamineSynaptic vesicular amine transportertarget
DB01454MidomafetamineSodium-dependent dopamine transportertarget
DB01454Midomafetamine5-hydroxytryptamine receptor 2Atarget
DB01454Midomafetamine5-hydroxytryptamine receptor 2Btarget
DB01454Midomafetamine5-hydroxytryptamine receptor 2Ctarget
DB01454MidomafetamineSodium-dependent noradrenaline transportertarget
DB01454MidomafetamineSodium-dependent noradrenaline transportertransporter
DB01454MidomafetamineSodium-dependent dopamine transportertransporter
DB01454MidomafetamineSodium-dependent serotonin transportertransporter
DB01577MethamphetamineCytochrome P450 2D6enzyme
DB01577MethamphetamineSodium-dependent dopamine transportertarget
DB01577MethamphetamineSynaptic vesicular amine transportertarget
DB01577MethamphetamineTrace amine-associated receptor 1target
DB01577MethamphetamineSodium-dependent serotonin transportertarget
DB01577MethamphetamineSodium-dependent noradrenaline transportertarget
DB01577MethamphetamineChromaffin granule amine transportertarget
DB01577MethamphetamineAmine oxidase [flavin-containing] Atarget
DB01577MethamphetamineAmine oxidase [flavin-containing] Btarget
DB01577MethamphetamineAlpha-2A adrenergic receptortarget
DB01577MethamphetamineAlpha-2B adrenergic receptortarget
DB01577MethamphetamineAlpha-2C adrenergic receptortarget
DB01577MethamphetamineSolute carrier family 22 member 3transporter
DB01577MethamphetamineSolute carrier family 22 member 5transporter
DB139402,5-Dimethoxy-4-ethylthioamphetamine5-hydroxytryptamine receptor 2Atarget
DB139402,5-Dimethoxy-4-ethylthioamphetamine5-hydroxytryptamine receptor 2Ctarget