- Biogenic Monoamines
- Accession Number
Biogenic amines having only one amine moiety. Included in this group are all natural monoamines formed by the enzymatic decarboxylation of natural amino acids.
Drug Drug Description Carbidopa A dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms. Eletriptan A triptan used for the treatment of migraines. Zolmitriptan A member of the triptan class of 5-HT(1B/1D/1F) receptor agonist drugs used for the acute treatment of migraine with or without aura in adults. Norepinephrine A sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. Dipivefrin A prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma. Epinephrine A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. Sumatriptan A serotonin receptor agonist used to treat migraines and cluster headaches. Almotriptan A 5-HT1B/1D receptor agonist used to treat migraines. Naratriptan A 5-HT1B/1D receptor agonist used to treat migraines. Rizatriptan A 5-HT1B/1D receptor agonist used to treat migraines. Dopamine A catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. Frovatriptan A 5-HT1B/1D receptor agonist used to treat migraines. Melatonin An endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement. Levodopa A dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. 5-Methoxy-N,N-diisopropyltryptamine 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. Since 1999, there has been a... Bufotenine A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a... Indopan Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar. It was developed in the 1960's by Upjohn with the intention... Dimethyltryptamine Some people use this compound as a psychedelic inducing agent. Etryptamine Developed in the 1960's for use as an antidepressant before market withdrawal in 1962. N-acetylhistamine Not Available Histamine An ingredient of topical drugs for the relief of joint pain or muscle aches and pains. Droxidopa A medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease. Levonordefrin A topical sympathomimetic amine found in local anesthetic products that is used for nasal decongestion or vasoconstriction during dental procedures. Protokylol Protokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States. Serotonin For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product. Tyramine Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An... Synephrine Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer... Racepinephrine A bronchodilator used to treat intermittent asthma. Psilocybin Psilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA. Serdemetan Serdemetan has been used in trials studying the treatment of Neoplasms. Dopexamine Dopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer. Theodrenaline Theodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation). Octopamine Octopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as... Ibopamine Not Annotated Norfenefrine Not Annotated Adrenalone Not Annotated Deoxyepinephrine Sympathomimetic, vasoconstrictor agent. Tyramine O-sulfate Not Annotated N-acetylserotonin Not Available Diethyltryptamine Diethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine. Alprazolam A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression. Amphetamine A CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). N-Caffeoyltyramine Not Available Tryptamine Not Available
- Drugs & Drug Targets