Aminobenzoates

Derivatives of BENZOIC ACID that contain one or more amino groups attached to the benzene ring structure. Included under this heading are a broad variety of acid forms, salts, esters, and amides that include the aminobenzoate structure.
DrugDrug NameDrug Description
DB00233Aminosalicylic acidAn aminosalicylate drug used to induce remission in ulcerative colitis.
DB00345Aminohippuric acidA hippuric acid derivative injection utilized in the measurement of effective renal plasma flow (ERPF) and functional capacity of the renal excretory system.
DB00522BentiromideIndicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.
DB00604CisaprideA medication used to treat heartburn associated with GERD.
DB00695FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
DB00721ProcaineA local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block.
DB00784Mefenamic acidAn NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
DB00807ProparacaineA topical anesthetic used for ophthalmic practice.
DB00887BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
DB00892OxybuprocaineA local anesthetic used in ophthalmology.
DB00939Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
DB01014BalsalazideAn aminosalicylate used to treat ulcerative colitis.
DB01035ProcainamideA medication used to treat life threatening ventricular arrhythmias.
DB01086BenzocaineA topical local anesthetic used for the temporary relief of pain and itching associated with minor burns, sunburn, scrapes and insect bites or minor skin irritations.
DB01161ChloroprocaineA local anesthetic agent indicated for intrathecal injection in adults for the production of subarachnoid block, or spinal anesthesia.
DB01233MetoclopramideAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
DB01487EmbutramideNot Available
DB02266Flufenamic acidAn anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th...
DB02362Aminobenzoic acidA member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic...
DB03126Mant-AdpNot Available
DB036443-hydroxyanthranilic acidAn oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
DB04166Anthranilic acidNot Available
DB04500AcedobenNot Available
DB04552Niflumic acidUsed in the treatment of rheumatoid arthritis.
DB05507VX-765Investigated for use/treatment in inflammatory disorders (unspecified) and psoriasis and psoriatic disorders.
DB06421DeclopramideInvestigated for use/treatment in colorectal cancer and inflammatory bowel disease.
DB07615TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
DB087484-(DIMETHYLAMINO)BENZOIC ACIDNot Available
DB08976FloctafenineAn anti-inflammatory analgesic used to manage mild to moderate acute pain.
DB08984EtofenamateEtofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).
DB09018BromoprideBromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the...
DB09085TetracaineA local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures.
DB09216Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
DB09285MorniflumateMorniflumate is indicated for the treatment of inflammatory conditions affecting the airways, ENT system, urogenital tract and bone and joint systems in adults. In Italy, morniflumate is also indicated for...
DB09320Procaine benzylpenicillinA local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection.
DB09342PropoxycainePropoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures . It has been combined with procaine to accelerate its onset of action and...
DB09347Acetrizoic acidAcetrizoic acid indication was to be used as a contrast agent for X-ray. Some information indicates its nephrotropic property as one of the characteristics for the utilization of acetrizoic acid....
DB11096MeradimateAn ingredient used in sunscreens to absorb UV radiation.
DB11148ButambenAnesthesia of mucus membranes other than the eyes.
DB11229Padimate APadimate A is an ester derivative of PABA and an ingredient in some sunscreens. It absorbs ultraviolet rays thereby preventing sunburn, however, its chemical structure and behaviour is similar to...
DB11570Padimate OAn ingredient used in sunscreens to absorb UV radiation.
DB12325IdasanutlinIdasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia.
DB12800CHF-6001CHF6001 has been used in trials studying the treatment of Asthma and Chronic Obstructive Pulmonary Disease.
DB12805AtaciguatAtaciguat has been investigated for the basic science of Aortic Valve Stenosis.
DB13039AminaphthoneAminaftone has been investigated for the treatment of Cockett Syndrome, May-Thurner Syndrome, and Iliac Vein Obstruction.
DB06422TicaloprideInvestigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.
DB14980AZD-6482AZD-6482 is under investigation in clinical trial NCT00688714 (Study to Investigate Safety and Tolerability of a Single Dose of AZD6482).
DrugDrug NameTargetType
DB00233Aminosalicylic acid2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinasetarget
DB00233Aminosalicylic acidGroup IIE secretory phospholipase A2target
DB00233Aminosalicylic acidProstaglandin G/H synthase 2target
DB00233Aminosalicylic acidArachidonate 5-lipoxygenasetarget
DB00233Aminosalicylic acidInhibitor of nuclear factor kappa-B kinase subunit alphatarget
DB00233Aminosalicylic acidMyeloperoxidaseenzyme
DB00345Aminohippuric acidSolute carrier family 22 member 2transporter
DB00345Aminohippuric acidSolute carrier family 22 member 5transporter
DB00345Aminohippuric acidSolute carrier family 22 member 6transporter
DB00345Aminohippuric acidSolute carrier family 22 member 8transporter
DB00345Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 4transporter
DB00345Aminohippuric acidSolute carrier family 22 member 11transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
DB00345Aminohippuric acidMultidrug resistance-associated protein 1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
DB00345Aminohippuric acidMonocarboxylate transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 7transporter
DB00522BentiromideSerine protease hepsintarget
DB00604Cisapride5-hydroxytryptamine receptor 4target
DB00604Cisapride5-hydroxytryptamine receptor 3Atarget
DB00604CisapridePotassium voltage-gated channel subfamily H member 2target
DB00604Cisapride5-hydroxytryptamine receptor 2Atarget
DB00604CisaprideCytochrome P450 3A4enzyme
DB00604CisaprideCytochrome P450 3A5enzyme
DB00604CisaprideCytochrome P450 3A7enzyme
DB00604CisaprideCytochrome P450 2A6enzyme
DB00604CisaprideCytochrome P450 2B6enzyme
DB00604CisaprideCytochrome P450 2C19enzyme
DB00604CisaprideCytochrome P450 2C8enzyme
DB00604CisaprideCytochrome P450 2C9enzyme
DB00604CisaprideCytochrome P450 2D6enzyme
DB00695FurosemideSolute carrier family 12 member 1target
DB00695FurosemideSerum albumincarrier
DB00695FurosemideSolute carrier family 22 member 6transporter
DB00695FurosemideSolute carrier family 22 member 5transporter
DB00695FurosemideSolute carrier family 22 member 8transporter
DB00695FurosemideCanalicular multispecific organic anion transporter 1transporter
DB00695FurosemideSolute carrier organic anion transporter family member 2A1transporter
DB00695FurosemideSolute carrier family 22 member 11transporter
DB00695Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00695FurosemideCarbonic anhydrase 2target
DB00695FurosemideUDP-glucuronosyltransferase 1-1enzyme
DB00695FurosemideThyroxine-binding globulincarrier
DB00721ProcaineSodium channel protein type 10 subunit alphatarget
DB00721ProcaineGlutamate receptor ionotropic, NMDA 3Atarget
DB00721Procaine5-hydroxytryptamine receptor 3Atarget
DB00721ProcaineSodium-dependent dopamine transportertarget
DB00721ProcaineNeuronal acetylcholine receptor subunit alpha-2target
DB00721ProcaineCholinesteraseenzyme
DB00721ProcaineDNAtarget
DB00721ProcaineCalcium-activated potassium channeltarget
DB00721ProcaineCytosolic phospholipase A2target
DB00721Procaine60 kDa lysophospholipasetarget
DB00721ProcaineMonoamine oxidasetarget
DB00784Mefenamic acidProstaglandin G/H synthase 2target
DB00784Mefenamic acidProstaglandin G/H synthase 1target
DB00784Mefenamic acidCytochrome P450 2C9enzyme
DB00784Mefenamic acidCytochrome P450 2C8enzyme
DB00784Mefenamic acidSerum albumincarrier
DB00784Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
DB00807ProparacaineSodium channel protein type 10 subunit alphatarget
DB00887BumetanideSolute carrier family 12 member 1target
DB00887BumetanideCystic fibrosis transmembrane conductance regulatortarget
DB00887BumetanideSolute carrier family 12 member 2target
DB00887BumetanideSolute carrier family 12 member 4target
DB00887BumetanideSolute carrier family 12 member 5target
DB00887BumetanideSodium/bile acid cotransportertransporter
DB00887BumetanideSolute carrier family 22 member 6transporter
DB00887BumetanideSolute carrier family 22 member 8transporter
DB00887BumetanideSolute carrier family 22 member 11transporter
DB00887BumetanideSolute carrier family 22 member 7transporter
DB00887BumetanideSolute carrier organic anion transporter family member 1A2transporter
DB00887BumetanideProstaglandin G/H synthase 2enzyme
DB00892OxybuprocaineSodium channel protein type 10 subunit alphatarget
DB00892OxybuprocaineCholinesteraseenzyme
DB00939Meclofenamic acidProstaglandin G/H synthase 1target
DB00939Meclofenamic acidProstaglandin G/H synthase 2target
DB00939Meclofenamic acidArachidonate 5-lipoxygenasetarget
DB00939Meclofenamic acidSolute carrier family 22 member 6transporter
DB00939Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
DB00939Meclofenamic acidThyroxine-binding globulincarrier
DB01014BalsalazideProstaglandin G/H synthase 1target
DB01014BalsalazideProstaglandin G/H synthase 2target
DB01014BalsalazideArachidonate 5-lipoxygenasetarget
DB01014BalsalazidePeroxisome proliferator-activated receptor gammatarget
DB01014BalsalazideNADPH azoreductaseenzyme
DB01035ProcainamideSodium channel protein type 5 subunit alphatarget
DB01035ProcainamideDNA (cytosine-5)-methyltransferase 1target
DB01035ProcainamideCytochrome P450 2D6enzyme
DB01035ProcainamideCholinesteraseenzyme
DB01035ProcainamideSolute carrier family 22 member 2transporter
DB01035ProcainamideSolute carrier family 22 member 1transporter
DB01035ProcainamideSolute carrier family 22 member 3transporter
DB01035ProcainamideSolute carrier family 22 member 5transporter
DB01035ProcainamideSolute carrier family 22 member 4transporter
DB01035ProcainamidePotassium voltage-gated channel subfamily H member 2target
DB01035ProcainamideMultidrug and toxin extrusion protein 1transporter
DB01035ProcainamideMultidrug and toxin extrusion protein 2transporter
DB01086BenzocaineSodium channel protein type 10 subunit alphatarget
DB01086BenzocaineP-glycoprotein 1transporter
DB01086BenzocaineLiver carboxylesterase 1enzyme
DB01161ChloroprocaineSodium channel protein type 10 subunit alphatarget
DB01161ChloroprocaineNeuronal acetylcholine receptor subunit alpha-10target
DB01161ChloroprocaineSodium-dependent dopamine transportertarget
DB01161ChloroprocaineGlutamate receptor ionotropic, NMDA 3Atarget
DB01161Chloroprocaine5-hydroxytryptamine receptor 3Atarget
DB01161ChloroprocaineCholinesteraseenzyme
DB01233MetoclopramideMuscarinic acetylcholine receptor M1target
DB01233MetoclopramideDopamine D2 receptortarget
DB01233MetoclopramideCytochrome P450 2D6enzyme
DB01233Metoclopramide5-hydroxytryptamine receptor 4target
DB01233Metoclopramide5-hydroxytryptamine receptor 3Atarget
DB01233MetoclopramideCytochrome P450 3A4enzyme
DB01233MetoclopramideCytochrome P450 1A2enzyme
DB01233MetoclopramideP-glycoprotein 1transporter
DB01233MetoclopramideAlpha-1-acid glycoprotein 1carrier
DB02266Flufenamic acidAldo-keto reductase family 1 member C3target
DB02266Flufenamic acidTransthyretincarrier
DB02266Flufenamic acidProstaglandin G/H synthase 2target
DB02266Flufenamic acidProstaglandin G/H synthase 1target
DB02266Flufenamic acidSolute carrier family 22 member 6transporter
DB02266Flufenamic acidAndrogen receptortarget
DB02266Flufenamic acidPeroxisome proliferator-activated receptor alphatarget
DB02266Flufenamic acidPeroxisome proliferator-activated receptor gammatarget
DB02362Aminobenzoic acidp-hydroxybenzoate hydroxylasetarget
DB02362Aminobenzoic acidp-hydroxybenzoate hydroxylasetarget
DB03126Mant-AdpMyosin-14target
DB036443-hydroxyanthranilic acidTrans-2,3-dihydro-3-hydroxyanthranilate isomerasetarget
DB04166Anthranilic acidL-amino-acid oxidasetarget
DB04166Anthranilic acidD-amino-acid oxidasetarget
DB04552Niflumic acidPhospholipase A2target
DB04552Niflumic acidChloride channel protein ClC-Katarget
DB04552Niflumic acidMonocarboxylate transporter 2transporter
DB04552Niflumic acidMonocarboxylate transporter 1transporter
DB04552Niflumic acidProstaglandin G/H synthase 2target
DB04552Niflumic acidProstaglandin G/H synthase 1target
DB04552Niflumic acidCytosolic phospholipase A2target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
DB05507VX-765Caspase-1target
DB05507VX-765Interleukin-1 betatarget
DB06421DeclopramideDNAtarget
DB06421DeclopramideDNA topoisomerase 2-alphatarget
DB06421DeclopramideDNA topoisomerase 2-betatarget
DB07615TranilastHematopoietic prostaglandin D synthasetarget
DB07615TranilastCytochrome P450 3A4enzyme
DB07615TranilastCytochrome P450 2C9enzyme
DB087484-(DIMETHYLAMINO)BENZOIC ACIDReplicase polyprotein 1abtarget
DB087484-(DIMETHYLAMINO)BENZOIC ACIDOrf1a polyproteintarget
DB08984EtofenamateThyroxine-binding globulincarrier
DB09018BromoprideDopamine D2 receptortarget
DB09085TetracaineRyanodine receptor 1target
DB09085TetracaineRyanodine receptor 2target
DB09085TetracaineVoltage-gated sodium channel alpha subunittarget
DB09216Tolfenamic acidProstaglandin G/H synthase 1target
DB09216Tolfenamic acidProstaglandin G/H synthase 2target
DB09216Tolfenamic acidCytochrome P450 3A4enzyme
DB09285MorniflumateArachidonate 5-lipoxygenasetarget
DB09285MorniflumateProstaglandin G/H synthase 2target
DB09285MorniflumateArachidonate 5-lipoxygenaseenzyme
DB09285MorniflumateProstaglandin G/H synthase 2enzyme
DB09285MorniflumateLeukotriene B4 receptor 1target
DB09285MorniflumateThromboxane A2 receptortarget
DB09285MorniflumateUDP-glucuronosyltransferase 1-9enzyme
DB09342PropoxycaineLiver carboxylesterase 1enzyme
DB09342PropoxycaineVoltage-gated sodium channel alpha subunittarget
DB09347Acetrizoic acidSerum albumincarrier
DB11148ButambenVoltage-dependent calcium channeltarget
DB11148ButambenCholinesteraseenzyme
DB11148ButambenAlpha-1-acid glycoprotein 1carrier
DB11148ButambenSerum albumincarrier
DB11148ButambenATP-sensitive potassium channeltarget
DB11148ButambenTransient receptor potential cation channel subfamily A member 1target
DB11148ButambenTransient receptor potential cation channel subfamily V member 4target
DB06422Ticalopride5-hydroxytryptamine receptor 4target
DB06422Ticalopride5-hydroxytryptamine receptor 3Atarget