Hormonal Contraceptives for Systemic Use

Chemical substances that prevent or reduce the probability of CONCEPTION.
DrugDrug NameDrug Indication
DB00823Ethynodiol diacetateFor the prevention of pregnancy in women who elect to use this product as a method of contraception.
DB00834MifepristoneFor the medical termination of intrauterine pregnancy through 49 days' pregnancy. Also indicated to control hyperglycemia secondary to hypercortisolism in adult patients with endogenous Cushing's syndrome who have type 2 diabetes mellitus or glucose intolerance and are not candidates for surgery or have had unsuccessful surgery.
DB04066para-Coumaric AcidNot Available
DB04574Estrone sulfateEstropipate is used for the treatment of moderate to severe vasomotor symptoms associated with the monopause, and moderate to severe symptoms of vulval and vaginal atrophy associated with the menopause. It is also used to treat hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and prevent postmenopausal osteoporosis.
DB04682Octylphenoxy polyethoxyethanolNot Available
DB04839Cyproterone acetateFor the palliative treatment of patients with advanced prostatic carcinoma.
DB05830TrestoloneInvestigated for use/treatment in contraception and male hormonal deficiencies/abnormalities.
DB06266LonidamineInvestigated for use/treatment in benign prostatic hyperplasia, prostate disorders, and cancer/tumors (unspecified).
DB06804Nonoxynol-9Nonoxynol 9 is a surfactant spermicide used for contraception in spermicidal creams, jellies, foams, gel, and lubricants. It is also used in conjuction with other methods of contraception, including condoms, cervical caps and diaphragms.
DB09371NorethynodrelNot Available
DB09401IsosorbideIndicated for the prevention and treatment of angina pectoris due to coronary artery disease. The onset of action of oral isosorbide mononitrate is not sufficiently rapid for this product to be useful in aborting an acute anginal episode.[label]
DB11507CloprostenolNot Available
DB11619GestrinoneEndometriosis with or without accompanying sterility. Treatment is limited to a single course of 6 months duration per lifetime [L1699, L1700].
DB12025TriptolideNot Available
DB13044GossypolNot Available
DB13953Estradiol benzoateEstradiol benzoate is not currently available in any FDA or Health Canada approved products.
DB13954Estradiol cypionateDepo-Estradiol intramuscular depot injection is indicated for the treatment of moderate to severe vasomotor symptoms and hypoestrogenism due to hypogonadism.
DB13956Estradiol valerateEstradiol valerate is commercially available as an intramuscular injection as the product Delestrogen and is indicated for the treatment of moderate to severe vasomotor symptoms and vulvovaginal atrophy due to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and for the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation only). Estradiol valerate is also available in combination with [DB09123] as the commercially available product Natazia used for the prevention of pregnancy and for the treatment of heavy menstrual bleeding.
DB00294EtonogestrelEtonogestrel is administered in subdermal implants as long-acting reversible contraception. It is known to be effective in postpartum insertion including breastfeeding women.[A175990] Etonogestrel is part of the long-acting contraceptive implants that prevent pregnancy. The implant's effect can remain for 5 years.[L5698]
DB00367LevonorgestrelFor the treatment of menopausal and postmenopausal disorders and alone or in combination with other hormones as an oral contraceptive.
DB00717NorethisteroneFor the treatment of secondary amenorrhea, endometriosis, and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as submucous fibroids or uterine cancer.
DB00977EthinylestradiolFor treatment of moderate to severe vasomotor symptoms associated with the menopause, female hypogonadism, prostatic carcinoma-palliative therapy of advanced disease, breast cancer, as an oral contraceptive, and as emergency contraceptive.
DB01395DrospirenoneFor the prevention of pregnancy in women who elect an oral contraceptive.
DB06713NorelgestrominNorelgestromin is used for contraception and menopausal hormonal therapy. Norelgestromin may potentially be used in breast cancer treatment due to its inhibitory effect on estrone sulfatase . They convert sulfated steroid precursors to estrogen during pregnancy.
DB06730GestodeneNot Available
DB09123DienogestIndicated for use as the treatment of endometriosis alone and as a contraceptive in combination with ethinylestradiol.
DB09389NorgestrelNorgestrel in combination with ethinyl estradiol is indicated for the prevention of pregnancy in women who elect to use this product as a method of contraception.
DB13528ChlormadinoneNot Available
DB13563NorgestrienoneNot Available
DB13685QuingestanolNot Available
DB13866EtynodiolNot Available
DB13310OrmeloxifeneNot Available
DB00255DiethylstilbestrolUsed in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
DB00304DesogestrelOral desogestrel is used in combination with [ethinylestradiol] as a contraceptive agent for the prevention of pregnancy.[FDA label] Desogestrel is part of the combined oral contraceptives that contain a mix of estrogen and progestin which inhibit ovulation.[L5698]
DB00351Megestrol acetateFor the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). Also used for the palliative management of recurrent, inoperable, or metastatic breast cancer, endometrial cancer, and prostate cancer in Canada and some other countries.
DB00603Medroxyprogesterone acetateUsed as a contraceptive and to treat secondary amenorrhea, abnormal uterine bleeding, pain associated with endometriosis, endometrial and renal cell carcinomas, paraphilia in males, GnRH-dependent forms of precocious puberty, as well as to prevent endometrial changes associated with estrogens.
DB00783EstradiolEstradiol is indicated for the treatment of moderate to severe vasomotor symptoms and vulvar and vaginal atrophy due to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration, or primary ovarian failure, and for the prevention of post-menopausal osteoarthritis. It is also used for the treatment of breast cancer (for palliation only) in appropriately selected women and men with metastatic disease, and for the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation only).
DB00957NorgestimateFor the prevention of pregnancy
DB08867UlipristalAs the product Ella (available in Canada and the US), ulipristal is indicated for use as emergency contraception after unprotected intercourse or possible contraceptive failure when administered within 120 hours (5 days) after unprotected intercourse or a known or suspected contraceptive failure. As the product Fibristal (available in Canada), ulipristal is indicated for treatment of the signs and symptoms of uterine fibroids in adult women.
DB11636NomegestrolNot Available
DB12474LynestrenolNot Available
DB05384Carbopol 974PInvestigated for use/treatment in contraception and HIV prevention.
DB06789Hydroxyprogesterone caproateHydroxyprogesterone caproate is indicated for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth. (1)
DB01357MestranolMestranol was used as one of the first oral contraceptives.
DB13981Nomegestrol acetateNot Available
DB01115NifedipineFor the management of vasospastic angina, chronic stable angina, hypertension, and Raynaud's phenomenon. May be used as a first line agent for left ventricular hypertrophy and isolated systolic hypertension (long-acting agents).
DB13944Testosterone enanthateTestosterone enanthate in males is indicated as a replacement therapy in conditions associated with a deficiency or absence of endogenous testosterone. Some of the treated conditions are 1) primary hypogonadism, defined as testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome or orchidectomy; 2) hypogonadotropic hypogonadism due to an idiopathic gonadotropin or luteinizing hormone-releasing hormone deficiency or due to a pituitary-hypothalamic injury from tumors, trauma or radiation, in this case it is important to accompany the treatment with adrenal cortical and thyroid hormone replacement therapy; 3) to stimulate puberty in patients with delayed puberty not secondary to a pathological disorder. If the conditions 1 and 2 occur prior to puberty, the androgen replacement therapy will be needed during adolescent years for the development of secondary sexual characteristics and prolonged androgen treatment might be needed it to maintain sexual characteristics after puberty.[FDA label] In females, testosterone enanthate is indicated to be used secondarily in presence of advanced inoperable metastatic mammary cancer in women who are from one to five years postmenopausal. It has also been used in premenopausal women with breast cancer who have benefited from oophorectomy and are considered to have a hormone-responsive tumor.[FDA label] Testosterone enanthate injections that are currently formulated for subcutaneous use are specifically indicated only for primary hypogonadism and hypogonadotropic hypogonadism [F1941]. The use of such formulations is limited because the safety and efficacy of these subcutaneous products in adult males with late-onset hypogonadism and males less than 18 years old have not yet been established [F1941]. Moreover, subcutaneously administered testosterone enanthate is indicated only for the treatment of men with hypogonadal conditions associated with structural or genetic etiologies, considering the medication could cause blood pressure increases that can raise the risk of major adverse cardiovascular events like non-fatal myocardial infarction, non-fatal stroke, and cardiovascular death [F1941].
DB00396Progesterone**Gelatinized capsules** The gelatinized capsules are indicated for use in the prevention of endometrial hyperplasia in non-hysterectomized postmenopausal women who are receiving conjugated estrogens tablets. They are also indicated for use in secondary amenorrhea [FDA label]. **Vaginal gel** Progesterone gel (8%) is indicated as progesterone supplementation or replacement as part of an Assisted Reproductive Technology (“ART”) treatment for infertile women with progesterone deficiency. The lower concentration progesterone gel (4%) is used in the treatment of secondary amenorrhea, with the use of the 8% concentration if there is no therapeutic response to the 4% gel [F3898]. **Vaginal insert** This form is indicated to support embryo implantation and early pregnancy by supplementation of corpus luteal function as part of an Assisted Reproductive Technology (ART) treatment program for infertile women [F3901]. **Injection (intramuscular)** This drug is indicated in amenorrhea and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as submucous fibroids or uterine cancer [F3907]. **Tablets, contraceptive** The tablet form of progesterone in contraceptive formulations is indicated for the prevention of pregnancy [F3904].
DB13857DemegestoneNot Available
DB14583Segesterone acetateSegesterone acetate in combination with ethinyl estradiol is indicated for use by females of reproductive potential to prevent pregnancy as a combination hormonal contraceptive (CHC). It induces contraception for thirteen 28-day cycles (1 year) following vaginal administration. The vaginal system must remain in place continuously for 3 weeks (21 days) followed by a 1-week (7-day) vaginal system-free interval. The use in females with a body mass index of >29 kg/m^2 has not been adequately evaluated [FDA Label].
DB14678Norethindrone enanthateNot Available
DrugDrug NameTargetType
DB00823Ethynodiol diacetateEstrogen receptor alphatarget
DB00823Ethynodiol diacetateProgesterone receptortarget
DB00823Ethynodiol diacetateCytochrome P450 3A4enzyme
DB00834MifepristoneProgesterone receptortarget
DB00834MifepristoneGlucocorticoid receptortarget
DB00834MifepristoneCytochrome P450 3A4enzyme
DB00834MifepristoneCytochrome P450 3A5enzyme
DB00834MifepristoneCytochrome P450 3A7enzyme
DB00834MifepristoneMultidrug resistance protein 1transporter
DB00834MifepristoneMultidrug resistance-associated protein 1transporter
DB00834MifepristoneCytochrome P450 2D6enzyme
DB00834MifepristoneProstate-specific antigentarget
DB00834MifepristoneNuclear receptor subfamily 1 group I member 2target
DB00834MifepristoneBile salt export pumptransporter
DB00834MifepristoneCytochrome P450 2C8enzyme
DB00834MifepristoneCytochrome P450 2C9enzyme
DB00834MifepristoneSolute carrier organic anion transporter family member 1B1transporter
DB00834MifepristoneSolute carrier organic anion transporter family member 1B3transporter
DB04066para-Coumaric AcidPhotoactive yellow proteintarget
DB04066para-Coumaric AcidPPHtarget
DB04066para-Coumaric AcidProstaglandin reductase 1target
DB04066para-Coumaric AcidHistidine ammonia-lyasetarget
DB04574Estrone sulfateCytochrome P450 1A2enzyme
DB04574Estrone sulfateCytochrome P450 3A4enzyme
DB04574Estrone sulfateEstrogen receptor alphatarget
DB04574Estrone sulfateEstrogen receptor betatarget
DB04574Estrone sulfateSex hormone-binding globulincarrier
DB04574Estrone sulfateSerum albumincarrier
DB04574Estrone sulfateCytochrome P450 2C9enzyme
DB04574Estrone sulfateMultidrug and toxin extrusion protein 1transporter
DB04574Estrone sulfateMultidrug and toxin extrusion protein 2transporter
DB04682Octylphenoxy polyethoxyethanolTroponin C, skeletal muscletarget
DB04839Cyproterone acetateAndrogen receptortarget
DB04839Cyproterone acetateCytochrome P450 19A1enzyme
DB04839Cyproterone acetateProstate-specific antigentarget
DB04839Cyproterone acetateCytochrome P450 3A4enzyme
DB06266LonidamineCystic fibrosis transmembrane conductance regulatortarget
DB06266LonidamineHexokinase-1target
DB06804Nonoxynol-9Prostaglandin G/H synthase 2enzyme
DB09371NorethynodrelEstrogen receptor alphatarget
DB09371NorethynodrelAndrogen receptortarget
DB09371NorethynodrelSex hormone-binding globulintarget
DB09371NorethynodrelCytochrome P450 3A4enzyme
DB09401IsosorbideApoptosis regulator Bcl-2target
DB09401IsosorbideBcl-2-like protein 1target
DB09401IsosorbideInduced myeloid leukemia cell differentiation protein Mcl-1target
DB11619GestrinoneSex hormone-binding globulintarget
DB11619GestrinoneProgesterone receptortarget
DB11619GestrinoneGlucocorticoid receptortarget
DB11619GestrinoneAndrogen receptortarget
DB11619GestrinoneGonadotropin-releasing hormone receptortarget
DB11619GestrinoneEstrogen receptor alphatarget
DB11619GestrinoneCytochrome P450 3A4enzyme
DB13044GossypolBcl-2-like protein 1target
DB13953Estradiol benzoateEstrogen receptor alphatarget
DB13953Estradiol benzoateNuclear receptor subfamily 1 group I member 2target
DB13953Estradiol benzoateSex hormone-binding globulincarrier
DB13953Estradiol benzoateEstrogen receptor betatarget
DB13953Estradiol benzoateCytochrome P450 1A2enzyme
DB13953Estradiol benzoateUDP-glucuronosyltransferase 1-1enzyme
DB13953Estradiol benzoateSerum albumincarrier
DB13953Estradiol benzoateFatty acid-binding protein, intestinalcarrier
DB13953Estradiol benzoateCytochrome P450 3A4enzyme
DB13953Estradiol benzoateCytochrome P450 3A5enzyme
DB13953Estradiol benzoateCytochrome P450 3A7enzyme
DB13953Estradiol benzoateSolute carrier family 22 member 2transporter
DB13953Estradiol benzoateSolute carrier family 22 member 1transporter
DB13953Estradiol benzoateSolute carrier family 22 member 3transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 2B1transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 1A2transporter
DB13953Estradiol benzoateMultidrug resistance-associated protein 7transporter
DB13953Estradiol benzoateSolute carrier family 22 member 11transporter
DB13953Estradiol benzoateATP-binding cassette sub-family G member 2transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 1B1transporter
DB13953Estradiol benzoateMultidrug resistance protein 1transporter
DB13953Estradiol benzoateCytochrome P450 1A1enzyme
DB13953Estradiol benzoateCytochrome P450 1B1enzyme
DB13953Estradiol benzoateCytochrome P450 2C19enzyme
DB13953Estradiol benzoateCytochrome P450 2C8enzyme
DB13953Estradiol benzoateCytochrome P450 2C9enzyme
DB13953Estradiol benzoateSolute carrier family 22 member 8transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 1B3transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 1C1transporter
DB13953Estradiol benzoateSolute carrier organic anion transporter family member 4A1transporter
DB13953Estradiol benzoateNeuronal acetylcholine receptor subunit alpha-4target
DB13953Estradiol benzoateNuclear receptor coactivator 2target
DB13953Estradiol benzoateG-protein coupled estrogen receptor 1target
DB13953Estradiol benzoateATP synthase subunit atarget
DB13953Estradiol benzoateBeclin-1target
DB13953Estradiol benzoateEstradiol 17-beta-dehydrogenase 2target
DB13953Estradiol benzoateEstrogen-related receptor gammatarget
DB13954Estradiol cypionateEstrogen receptor alphatarget
DB13954Estradiol cypionateNuclear receptor subfamily 1 group I member 2target
DB13954Estradiol cypionateSex hormone-binding globulincarrier
DB13954Estradiol cypionateEstrogen receptor betatarget
DB13954Estradiol cypionateCytochrome P450 1A2enzyme
DB13954Estradiol cypionateUDP-glucuronosyltransferase 1-1enzyme
DB13954Estradiol cypionateSerum albumincarrier
DB13954Estradiol cypionateFatty acid-binding protein, intestinalcarrier
DB13954Estradiol cypionateCytochrome P450 3A4enzyme
DB13954Estradiol cypionateCytochrome P450 3A5enzyme
DB13954Estradiol cypionateCytochrome P450 3A7enzyme
DB13954Estradiol cypionateSolute carrier family 22 member 2transporter
DB13954Estradiol cypionateSolute carrier family 22 member 1transporter
DB13954Estradiol cypionateSolute carrier family 22 member 3transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 2B1transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1A2transporter
DB13954Estradiol cypionateMultidrug resistance-associated protein 7transporter
DB13954Estradiol cypionateSolute carrier family 22 member 11transporter
DB13954Estradiol cypionateATP-binding cassette sub-family G member 2transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1B1transporter
DB13954Estradiol cypionateMultidrug resistance protein 1transporter
DB13954Estradiol cypionateCytochrome P450 1A1enzyme
DB13954Estradiol cypionateCytochrome P450 1B1enzyme
DB13954Estradiol cypionateCytochrome P450 2C19enzyme
DB13954Estradiol cypionateCytochrome P450 2C8enzyme
DB13954Estradiol cypionateCytochrome P450 2C9enzyme
DB13954Estradiol cypionateSolute carrier family 22 member 8transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1B3transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 1C1transporter
DB13954Estradiol cypionateSolute carrier organic anion transporter family member 4A1transporter
DB13954Estradiol cypionateNeuronal acetylcholine receptor subunit alpha-4target
DB13954Estradiol cypionateNuclear receptor coactivator 2target
DB13954Estradiol cypionateG-protein coupled estrogen receptor 1target
DB13954Estradiol cypionateATP synthase subunit atarget
DB13954Estradiol cypionateBeclin-1target
DB13954Estradiol cypionateEstradiol 17-beta-dehydrogenase 2target
DB13954Estradiol cypionateEstrogen-related receptor gammatarget
DB13956Estradiol valerateEstrogen receptor alphatarget
DB13956Estradiol valerateNuclear receptor subfamily 1 group I member 2target
DB13956Estradiol valerateSex hormone-binding globulincarrier
DB13956Estradiol valerateEstrogen receptor betatarget
DB13956Estradiol valerateCytochrome P450 1A2enzyme
DB13956Estradiol valerateUDP-glucuronosyltransferase 1-1enzyme
DB13956Estradiol valerateSerum albumincarrier
DB13956Estradiol valerateFatty acid-binding protein, intestinalcarrier
DB13956Estradiol valerateCytochrome P450 3A4enzyme
DB13956Estradiol valerateCytochrome P450 3A5enzyme
DB13956Estradiol valerateCytochrome P450 3A7enzyme
DB13956Estradiol valerateSolute carrier family 22 member 2transporter
DB13956Estradiol valerateSolute carrier family 22 member 1transporter
DB13956Estradiol valerateSolute carrier family 22 member 3transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 2B1transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1A2transporter
DB13956Estradiol valerateMultidrug resistance-associated protein 7transporter
DB13956Estradiol valerateSolute carrier family 22 member 11transporter
DB13956Estradiol valerateATP-binding cassette sub-family G member 2transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1B1transporter
DB13956Estradiol valerateMultidrug resistance protein 1transporter
DB13956Estradiol valerateCytochrome P450 1A1enzyme
DB13956Estradiol valerateCytochrome P450 1B1enzyme
DB13956Estradiol valerateCytochrome P450 2C19enzyme
DB13956Estradiol valerateCytochrome P450 2C8enzyme
DB13956Estradiol valerateCytochrome P450 2C9enzyme
DB13956Estradiol valerateSolute carrier family 22 member 8transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1B3transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 1C1transporter
DB13956Estradiol valerateSolute carrier organic anion transporter family member 4A1transporter
DB13956Estradiol valerateNeuronal acetylcholine receptor subunit alpha-4target
DB13956Estradiol valerateNuclear receptor coactivator 2target
DB13956Estradiol valerateG-protein coupled estrogen receptor 1target
DB13956Estradiol valerateATP synthase subunit atarget
DB13956Estradiol valerateBeclin-1target
DB13956Estradiol valerateEstradiol 17-beta-dehydrogenase 2target
DB13956Estradiol valerateEstrogen-related receptor gammatarget
DB00294EtonogestrelEstrogen receptor alphatarget
DB00294EtonogestrelProgesterone receptortarget
DB00294EtonogestrelCytochrome P450 3A4enzyme
DB00294EtonogestrelSerum albumincarrier
DB00294EtonogestrelSex hormone-binding globulincarrier
DB00367LevonorgestrelProgesterone receptortarget
DB00367LevonorgestrelEstrogen receptor alphatarget
DB00367Levonorgestrel3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB00367LevonorgestrelCytochrome P450 3A4enzyme
DB00367LevonorgestrelCytochrome P450 19A1enzyme
DB00367LevonorgestrelAndrogen receptortarget
DB00367LevonorgestrelSex hormone-binding globulintarget
DB00717NorethisteroneProgesterone receptortarget
DB00717NorethisteroneCytochrome P450 3A4enzyme
DB00717NorethisteroneMultidrug resistance protein 1transporter
DB00717NorethisteroneCytochrome P450 2C19enzyme
DB00717NorethisteroneCytochrome P450 3A5enzyme
DB00717NorethisteroneCytochrome P450 3A7enzyme
DB00717NorethisteroneSerum albumincarrier
DB00717NorethisteroneSex hormone-binding globulincarrier
DB00977EthinylestradiolEstrogen receptor alphatarget
DB00977EthinylestradiolNuclear receptor subfamily 1 group I member 2target
DB00977EthinylestradiolCytochrome P450 3A4enzyme
DB00977EthinylestradiolCytochrome P450 2C8enzyme
DB00977EthinylestradiolBile salt export pumptransporter
DB00977EthinylestradiolSodium/bile acid cotransportertransporter
DB00977EthinylestradiolCanalicular multispecific organic anion transporter 1transporter
DB00977EthinylestradiolMultidrug resistance protein 1transporter
DB00977EthinylestradiolSex hormone-binding globulintarget
DB00977EthinylestradiolUDP-glucuronosyltransferase 1-1enzyme
DB01395DrospirenoneProgesterone receptortarget
DB01395DrospirenoneMineralocorticoid receptortarget
DB01395DrospirenoneAndrogen receptortarget
DB01395DrospirenoneProstaglandin G/H synthase 2enzyme
DB01395DrospirenoneCholinesteraseenzyme
DB01395DrospirenoneCytochrome P450 3A4enzyme
DB06713NorelgestrominSteryl-sulfataseenzyme
DB06713NorelgestrominProgesterone receptortarget
DB06713NorelgestrominSerum albumintarget
DB06713NorelgestrominAndrogen receptortarget
DB06713NorelgestrominCytochrome P450 3A4enzyme
DB06730GestodeneCytochrome P450 3A5enzyme
DB06730GestodeneCytochrome P450 3A7enzyme
DB06730GestodeneProgesterone receptortarget
DB06730GestodeneCytochrome P450 3A4enzyme
DB09123DienogestCytochrome P450 3A4enzyme
DB09123DienogestProgesterone receptortarget
DB09123DienogestAndrogen receptortarget
DB09389NorgestrelProgesterone receptortarget
DB09389Norgestrel3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB09389NorgestrelAndrogen receptortarget
DB09389NorgestrelCytochrome P450 3A4enzyme
DB09389NorgestrelCytochrome P450 19A1enzyme
DB13528ChlormadinoneCytochrome P450 3A4enzyme
DB13685QuingestanolCytochrome P450 3A4enzyme
DB13866EtynodiolCytochrome P450 3A4enzyme
DB00255DiethylstilbestrolEstrogen receptor alphatarget
DB00255DiethylstilbestrolEstrogen-related receptor gammatarget
DB00255DiethylstilbestrolTransthyretincarrier
DB00255DiethylstilbestrolCatechol O-methyltransferaseenzyme
DB00255DiethylstilbestrolCytochrome P450 19A1enzyme
DB00255DiethylstilbestrolATP-binding cassette sub-family G member 2transporter
DB00255DiethylstilbestrolMultidrug resistance protein 1transporter
DB00255DiethylstilbestrolEstrogen receptor betatarget
DB00255DiethylstilbestrolCytochrome P450 3A4enzyme
DB00255DiethylstilbestrolCytochrome P450 2C8enzyme
DB00255DiethylstilbestrolCytochrome P450 2C9enzyme
DB00255DiethylstilbestrolCytochrome P450 2E1enzyme
DB00255DiethylstilbestrolSteroid hormone receptor ERR1target
DB00255DiethylstilbestrolSteroid hormone receptor ERR2target
DB00255DiethylstilbestrolNuclear receptor coactivator 2target
DB00255DiethylstilbestrolNuclear receptor subfamily 1 group I member 2target
DB00255DiethylstilbestrolAndrogen receptortarget
DB00255DiethylstilbestrolSex hormone-binding globulintarget
DB00255DiethylstilbestrolSolute carrier organic anion transporter family member 1B1transporter
DB00255DiethylstilbestrolSolute carrier organic anion transporter family member 2B1transporter
DB00255DiethylstilbestrolBile salt export pumptransporter
DB00304DesogestrelProgesterone receptortarget
DB00304DesogestrelEstrogen receptor alphatarget
DB00304DesogestrelCytochrome P450 3A4enzyme
DB00304DesogestrelSerum albumincarrier
DB00304DesogestrelSex hormone-binding globulincarrier
DB00304DesogestrelCytochrome P450 2C9enzyme
DB00304DesogestrelUDP-glucuronosyltransferase 1-1enzyme
DB00351Megestrol acetateProgesterone receptortarget
DB00351Megestrol acetateGlucocorticoid receptortarget
DB00351Megestrol acetateMultidrug resistance protein 1transporter
DB00351Megestrol acetateCytochrome P450 3A4enzyme
DB00603Medroxyprogesterone acetateProgesterone receptortarget
DB00603Medroxyprogesterone acetateEstrogen receptor alphatarget
DB00603Medroxyprogesterone acetateCytochrome P450 3A4enzyme
DB00603Medroxyprogesterone acetateCytochrome P450 2C8enzyme
DB00603Medroxyprogesterone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
DB00603Medroxyprogesterone acetateCytochrome P450 2C9enzyme
DB00783EstradiolEstrogen receptor alphatarget
DB00783EstradiolNuclear receptor subfamily 1 group I member 2target
DB00783EstradiolSex hormone-binding globulincarrier
DB00783EstradiolEstrogen receptor betatarget
DB00783EstradiolCytochrome P450 1A2enzyme
DB00783EstradiolUDP-glucuronosyltransferase 1-1enzyme
DB00783EstradiolSerum albumincarrier
DB00783EstradiolFatty acid-binding protein, intestinalcarrier
DB00783EstradiolCytochrome P450 3A4enzyme
DB00783EstradiolCytochrome P450 3A5enzyme
DB00783EstradiolCytochrome P450 3A7enzyme
DB00783EstradiolSolute carrier family 22 member 2transporter
DB00783EstradiolSolute carrier family 22 member 1transporter
DB00783EstradiolSolute carrier family 22 member 3transporter
DB00783EstradiolSolute carrier organic anion transporter family member 2B1transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1A2transporter
DB00783EstradiolMultidrug resistance-associated protein 7transporter
DB00783EstradiolSolute carrier family 22 member 11transporter
DB00783EstradiolATP-binding cassette sub-family G member 2transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1B1transporter
DB00783EstradiolMultidrug resistance protein 1transporter
DB00783EstradiolCytochrome P450 1A1enzyme
DB00783EstradiolCytochrome P450 1B1enzyme
DB00783EstradiolCytochrome P450 2C19enzyme
DB00783EstradiolCytochrome P450 2C8enzyme
DB00783EstradiolCytochrome P450 2C9enzyme
DB00783EstradiolSolute carrier family 22 member 8transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1B3transporter
DB00783EstradiolSolute carrier organic anion transporter family member 1C1transporter
DB00783EstradiolSolute carrier organic anion transporter family member 4A1transporter
DB00783EstradiolNeuronal acetylcholine receptor subunit alpha-4target
DB00783EstradiolNuclear receptor coactivator 2target
DB00783EstradiolG-protein coupled estrogen receptor 1target
DB00783EstradiolATP synthase subunit atarget
DB00783EstradiolBeclin-1target
DB00783EstradiolEstradiol 17-beta-dehydrogenase 2target
DB00783EstradiolEstrogen-related receptor gammatarget
DB00957NorgestimateProgesterone receptortarget
DB00957NorgestimateEstrogen receptor alphatarget
DB00957NorgestimateCanalicular multispecific organic anion transporter 1transporter
DB00957NorgestimateCytochrome P450 3A4enzyme
DB00957NorgestimateAndrogen receptortarget
DB08867UlipristalProgesterone receptortarget
DB08867UlipristalGlucocorticoid receptortarget
DB08867UlipristalAndrogen receptortarget
DB08867UlipristalCytochrome P450 3A4enzyme
DB08867UlipristalCytochrome P450 1A2enzyme
DB08867UlipristalSerum albumincarrier
DB08867UlipristalAlpha-1-acid glycoprotein 1carrier
DB11636NomegestrolCytochrome P450 3A4enzyme
DB12474LynestrenolCytochrome P450 3A4enzyme
DB12474LynestrenolCytochrome P450 2C9enzyme
DB12474LynestrenolCytochrome P450 2C19enzyme
DB06789Hydroxyprogesterone caproateProgesterone receptortarget
DB06789Hydroxyprogesterone caproateCytochrome P450 3A4enzyme
DB06789Hydroxyprogesterone caproateCytochrome P450 3A5enzyme
DB06789Hydroxyprogesterone caproateCytochrome P450 2C19enzyme
DB01357MestranolEstrogen receptor alphatarget
DB01357MestranolCytochrome P450 2C9enzyme
DB01357MestranolCytochrome P450 3A4enzyme
DB01357MestranolCytochrome P450 2C8enzyme
DB13981Nomegestrol acetateCytochrome P450 3A4enzyme
DB01115NifedipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB01115NifedipineCytochrome P450 3A4enzyme
DB01115NifedipineCytochrome P450 2E1enzyme
DB01115NifedipineCytochrome P450 2D6enzyme
DB01115NifedipineCalmodulintarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01115NifedipinePotassium voltage-gated channel subfamily A member 1target
DB01115NifedipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB01115NifedipineCytochrome P450 1A2enzyme
DB01115NifedipineCytochrome P450 2A6enzyme
DB01115NifedipineCytochrome P450 2C8enzyme
DB01115NifedipineCytochrome P450 3A5enzyme
DB01115NifedipineCytochrome P450 3A7enzyme
DB01115NifedipineCanalicular multispecific organic anion transporter 2transporter
DB01115NifedipineMultidrug resistance protein 1transporter
DB01115NifedipineCanalicular multispecific organic anion transporter 1transporter
DB01115NifedipineCytochrome P450 1A1enzyme
DB01115NifedipineCytochrome P450 2B6enzyme
DB01115NifedipineNuclear receptor subfamily 1 group I member 2target
DB01115NifedipineSolute carrier organic anion transporter family member 1B1transporter
DB01115NifedipineBile salt export pumptransporter
DB13944Testosterone enanthateAndrogen receptortarget
DB13944Testosterone enanthateCytochrome P450 3A4enzyme
DB13944Testosterone enanthateCytochrome P450 19A1enzyme
DB13944Testosterone enanthateAmine oxidase [flavin-containing] Aenzyme
DB13944Testosterone enanthateCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB13944Testosterone enanthateSerum albumincarrier
DB13944Testosterone enanthateSex hormone-binding globulincarrier
DB13944Testosterone enanthateCytochrome P450 3A5enzyme
DB13944Testosterone enanthateCytochrome P450 3A7enzyme
DB13944Testosterone enanthateSolute carrier organic anion transporter family member 1A2transporter
DB13944Testosterone enanthateSolute carrier family 22 member 8transporter
DB13944Testosterone enanthateSolute carrier family 22 member 7transporter
DB13944Testosterone enanthateMultidrug resistance protein 1transporter
DB13944Testosterone enanthateSodium/bile acid cotransportertransporter
DB13944Testosterone enanthateSolute carrier family 22 member 3transporter
DB13944Testosterone enanthateSolute carrier family 22 member 4transporter
DB13944Testosterone enanthateATP-binding cassette sub-family G member 2transporter
DB13944Testosterone enanthateCytochrome P450 1A1enzyme
DB13944Testosterone enanthateCytochrome P450 1B1enzyme
DB13944Testosterone enanthateCytochrome P450 2A13enzyme
DB13944Testosterone enanthateCytochrome P450 2B6enzyme
DB13944Testosterone enanthateCytochrome P450 2C19enzyme
DB13944Testosterone enanthateCytochrome P450 2C8enzyme
DB13944Testosterone enanthateCytochrome P450 2C9enzyme
DB13944Testosterone enanthateCytochrome P450 3A43enzyme
DB13944Testosterone enanthateEstrogen receptor alphatarget
DB13944Testosterone enanthateMineralocorticoid receptortarget
DB13944Testosterone enanthate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
DB00396ProgesteroneProgesterone receptortarget
DB00396ProgesteroneEstrogen receptor alphatarget
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB00396ProgesteroneCytochrome P450 2C19enzyme
DB00396ProgesteroneCytochrome P450 2C9enzyme
DB00396ProgesteroneCytochrome P450 3A4enzyme
DB00396ProgesteroneCytochrome P450 3A5enzyme
DB00396ProgesteroneCytochrome P450 3A7enzyme
DB00396ProgesteroneMultidrug resistance protein 1transporter
DB00396ProgesteroneSolute carrier family 22 member 2transporter
DB00396ProgesteroneSolute carrier family 22 member 1transporter
DB00396ProgesteroneSolute carrier family 22 member 3transporter
DB00396ProgesteroneBile salt export pumptransporter
DB00396ProgesteroneMultidrug resistance-associated protein 1transporter
DB00396ProgesteroneSodium/bile acid cotransportertransporter
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB00396ProgesteroneCytochrome P450 1A1enzyme
DB00396ProgesteroneCytochrome P450 1B1enzyme
DB00396ProgesteroneCytochrome P450 2A6enzyme
DB00396ProgesteroneCytochrome P450 2D6enzyme
DB00396ProgesteroneMineralocorticoid receptortarget
DB00396ProgesteroneKappa-type opioid receptortarget
DB00396ProgesteroneAlpha-1-acid glycoprotein 1target
DB00396ProgesteroneGlucocorticoid receptortarget
DB00396ProgesteroneAndrogen receptortarget
DB00396ProgesteroneSex hormone-binding globulintarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B1transporter
DB00396ProgesteroneATP-binding cassette sub-family G member 2transporter
DB00396ProgesteroneEstrogen receptor betatarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B3transporter
DB13857DemegestoneProgesterone receptortarget
DB13857DemegestoneCytochrome P450 3A4enzyme
DB14583Segesterone acetateGlucocorticoid receptortarget
DB14583Segesterone acetateProgesterone receptortarget
DB14583Segesterone acetateAndrogen receptortarget
DB14583Segesterone acetateCytochrome P450 3A4enzyme