Adrenergic beta-2 Receptor Agonists

Name
Adrenergic beta-2 Receptor Agonists
Accession Number
DBCAT003416  (DBCAT000554, DBCAT002650)
Description

Compounds bind to and activate ADRENERGIC BETA-2 RECEPTORS.

Drugs
DrugDrug Description
BitolterolUsed to dilate air passages in the lungs that have become narrowed as a result of disease or inflammation. It is used in the treatment of asthma and chronic obstructive...
AbediterolAbediterol has been used in trials studying the treatment of Asthma, Chronic Obstructive Pulmonary Disease (COPD), and Chronic Obstructive Pulmonary Disease (COPD) and Asthma.
OrciprenalineA beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.
SalmeterolA long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD.
FormoterolAn inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.
SalbutamolA beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms.
ArformoterolA beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
IndacaterolAn inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma.
OlodaterolA long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
LevosalbutamolA beta-2 adrenergic receptor agonist used to treat COPD and asthma.
RitodrineAn adrenergic beta agonist used to treat premature labor.
TerbutalineA beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.
EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
IsoprenalineA non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block; it is structurally related to epinephrine.
ProcaterolA beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
ClenbuterolUsed as a bronchodilator in the treatment of asthma patients.
FenoterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
PirbuterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
BambuterolFor the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema.
DroxidopaA medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease.
ArbutamineUsed to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in...
DobutamineA beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery.
DipivefrinA prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma.
Ephedra sinica rootAn alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest.
IsoetharineFor the treatment of asthma, wheezing, and chronic asthmatic bronchitis.
PhenylpropanolamineA sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy.
VilanterolA long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
ProtokylolProtokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
RacepinephrineA bronchodilator used to treat intermittent asthma.
EtafedrineA beta-2 adrenoceptor agonist used to treat a cough associated with inflamed mucosa.
PF-00610355PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others.
HexoprenalineHexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.
BatefenterolBatefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.
Drugs & Drug Targets
DrugTargetType
BitolterolBeta-2 adrenergic receptortarget
OrciprenalineBeta-2 adrenergic receptortarget
SalmeterolBeta-2 adrenergic receptortarget
SalmeterolCytochrome P450 3A4enzyme
SalmeterolCytochrome P450 2C8enzyme
SalmeterolCytochrome P450 3A5enzyme
SalmeterolCytochrome P450 3A7enzyme
SalmeterolBeta-1 adrenergic receptortarget
SalmeterolBeta-3 adrenergic receptortarget
SalmeterolSerum albumincarrier
Salmeterolalpha1-acid glycoproteincarrier
SalmeterolSolute carrier family 22 member 1transporter
SalmeterolSolute carrier family 22 member 2transporter
SalmeterolSolute carrier family 22 member 3transporter
FormoterolBeta-2 adrenergic receptortarget
FormoterolBeta-1 adrenergic receptortarget
FormoterolBeta-3 adrenergic receptortarget
FormoterolCytochrome P450 2D6enzyme
FormoterolCytochrome P450 2C19enzyme
FormoterolCytochrome P450 2C9enzyme
FormoterolCytochrome P450 2A6enzyme
FormoterolUDP-glucuronosyltransferase 1A1enzyme
FormoterolUDP-glucuronosyltransferase 1-8enzyme
FormoterolUDP-glucuronosyltransferase 1-9enzyme
FormoterolUDP-glucuronosyltransferase 2B7enzyme
FormoterolUDP-glucuronosyltransferase 2B15enzyme
FormoterolSolute carrier family 22 member 1transporter
FormoterolSolute carrier family 22 member 4transporter
FormoterolSolute carrier family 22 member 5transporter
FormoterolSolute carrier family 22 member 3transporter
FormoterolSerum albumincarrier
SalbutamolBeta-2 adrenergic receptortarget
SalbutamolBeta-1 adrenergic receptortarget
SalbutamolCytochrome P450 3A4enzyme
SalbutamolBeta-3 adrenergic receptortarget
ArformoterolBeta-2 adrenergic receptortarget
ArformoterolCytochrome P450 2D6enzyme
ArformoterolCytochrome P450 2C19enzyme
ArformoterolCytochrome P450 2A6enzyme
ArformoterolCytochrome P450 2C9enzyme
IndacaterolBeta-2 adrenergic receptortarget
IndacaterolCytochrome P450 3A4enzyme
IndacaterolUDP-glucuronosyltransferase 1-1enzyme
IndacaterolP-glycoprotein 1transporter
OlodaterolBeta-2 adrenergic receptortarget
OlodaterolCytochrome P450 2C9enzyme
OlodaterolCytochrome P450 2C8enzyme
LevosalbutamolBeta-2 adrenergic receptortarget
LevosalbutamolCytochrome P450 3A4enzyme
LevosalbutamolCytochrome P450 2D6enzyme
LevosalbutamolSolute carrier organic anion transporter family member 1B1transporter
LevosalbutamolSolute carrier organic anion transporter family member 1B3transporter
RitodrineBeta-2 adrenergic receptortarget
Ritodrine6-phosphogluconate dehydrogenase, decarboxylatingenzyme
TerbutalineBeta-2 adrenergic receptortarget
TerbutalineCholinesteraseenzyme
TerbutalineBeta-3 adrenergic receptortarget
TerbutalineBeta-1 adrenergic receptortarget
EpinephrineAlpha-1A adrenergic receptortarget
EpinephrineBeta-1 adrenergic receptortarget
EpinephrineBeta-2 adrenergic receptortarget
EpinephrineSolute carrier family 22 member 2transporter
EpinephrineSolute carrier family 22 member 1transporter
EpinephrineCytochrome P450 2C9enzyme
EpinephrineCytochrome P450 3A4enzyme
EpinephrineAlpha-1B adrenergic receptortarget
EpinephrineAlpha-1D adrenergic receptortarget
EpinephrineAlpha-2A adrenergic receptortarget
EpinephrineAlpha-2B adrenergic receptortarget
EpinephrineTumor necrosis factortarget
EpinephrineCatechol O-methyltransferaseenzyme
EpinephrineMonoamine oxidaseenzyme
IsoprenalineBeta-1 adrenergic receptortarget
IsoprenalineBeta-2 adrenergic receptortarget
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit alphatarget
IsoprenalineBeta-3 adrenergic receptortarget
IsoprenalineMitogen-activated protein kinase 1target
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit betatarget
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit gammatarget
IsoprenalineCytochrome P450 1A1enzyme
IsoprenalineCAMP phosphodiesterasetarget
IsoprenalineSuperoxide dismutase [Cu-Zn]target
ProcaterolBeta-2 adrenergic receptortarget
ClenbuterolBeta-2 adrenergic receptortarget
ClenbuterolBeta-nerve growth factortarget
ClenbuterolTumor necrosis factortarget
ClenbuterolBeta-1 adrenergic receptortarget
ClenbuterolBeta-3 adrenergic receptortarget
ClenbuterolCytochrome P450 1A1enzyme
FenoterolBeta-2 adrenergic receptortarget
FenoterolBeta-1 adrenergic receptortarget
FenoterolBeta-3 adrenergic receptortarget
PirbuterolBeta-2 adrenergic receptortarget
PirbuterolBeta-1 adrenergic receptortarget
NorepinephrinePhenylalanine-4-hydroxylasetarget
NorepinephrineAlpha-1A adrenergic receptortarget
NorepinephrineAlpha-1B adrenergic receptortarget
NorepinephrineAlpha-1D adrenergic receptortarget
NorepinephrineAlpha-2A adrenergic receptortarget
NorepinephrineAlpha-2B adrenergic receptortarget
NorepinephrineAlpha-2C adrenergic receptortarget
NorepinephrineBeta-1 adrenergic receptortarget
NorepinephrineBeta-2 adrenergic receptortarget
NorepinephrineBeta-3 adrenergic receptortarget
NorepinephrineSolute carrier family 22 member 2transporter
NorepinephrineSolute carrier family 22 member 3transporter
NorepinephrineSolute carrier family 22 member 5transporter
NorepinephrineSolute carrier family 22 member 1transporter
NorepinephrinePOU domain, class 5, transcription factor 1transporter
NorepinephrineSodium-dependent noradrenaline transportertransporter
NorepinephrineSynaptic vesicular amine transportertarget
NorepinephrineChromaffin granule amine transportertarget
BambuterolBeta-2 adrenergic receptortarget
BambuterolCholinesteraseenzyme
DroxidopaPhenylalanine-4-hydroxylasetarget
DroxidopaAlpha-1A adrenergic receptortarget
DroxidopaAlpha-1B adrenergic receptortarget
DroxidopaAlpha-1D adrenergic receptortarget
DroxidopaAlpha-2A adrenergic receptortarget
DroxidopaAlpha-2B adrenergic receptortarget
DroxidopaAlpha-2C adrenergic receptortarget
DroxidopaBeta-1 adrenergic receptortarget
DroxidopaBeta-2 adrenergic receptortarget
DroxidopaBeta-3 adrenergic receptortarget
DroxidopaAromatic-L-amino-acid decarboxylaseenzyme
DroxidopaMonocarboxylate transporter 10transporter
DroxidopaSodium-dependent noradrenaline transportertransporter
ArbutamineBeta-1 adrenergic receptortarget
ArbutamineBeta-2 adrenergic receptortarget
ArbutamineBeta-3 adrenergic receptortarget
DobutamineBeta-1 adrenergic receptortarget
DobutamineCatechol O-methyltransferaseenzyme
DobutamineBeta-2 adrenergic receptortarget
DobutamineAlpha-1 adrenergic receptorstarget
DobutamineEstrogen receptor alphatarget
DipivefrinAlpha-2A adrenergic receptortarget
DipivefrinCholinesterasetarget
DipivefrinBeta-2 adrenergic receptortarget
DipivefrinAlpha-1A adrenergic receptortarget
DipivefrinAcetylcholinesterasetarget
Ephedra sinica rootSodium-dependent dopamine transportertarget
Ephedra sinica rootSynaptic vesicular amine transportertarget
Ephedra sinica rootChromaffin granule amine transportertarget
Ephedra sinica rootSodium-dependent noradrenaline transportertarget
Ephedra sinica rootAmine oxidase [flavin-containing] Atarget
Ephedra sinica rootAmine oxidase [flavin-containing] Btarget
Ephedra sinica rootSodium-dependent serotonin transportertarget
Ephedra sinica rootAlpha-2A adrenergic receptortarget
Ephedra sinica rootAlpha-2B adrenergic receptortarget
Ephedra sinica rootAlpha-2C adrenergic receptortarget
Ephedra sinica rootBeta-1 adrenergic receptortarget
Ephedra sinica rootBeta-2 adrenergic receptortarget
Ephedra sinica rootBeta-3 adrenergic receptortarget
IsoetharineBeta-1 adrenergic receptortarget
IsoetharineBeta-2 adrenergic receptortarget
PhenylpropanolamineAmine oxidase [flavin-containing] Aenzyme
PhenylpropanolamineDopamine D1 receptortarget
PhenylpropanolamineBeta-1 adrenergic receptortarget
PhenylpropanolamineBeta-2 adrenergic receptortarget
PhenylpropanolamineAlpha-2 adrenergic receptorstarget
VilanterolCytochrome P450 3A4enzyme
VilanterolBeta-2 adrenergic receptortarget
CeliprololBeta-1 adrenergic receptortarget
CeliprololBeta-2 adrenergic receptortarget
CeliprololBeta-3 adrenergic receptortarget
CeliprololAlpha-2A adrenergic receptortarget
CeliprololAlpha-2B adrenergic receptortarget
CeliprololAlpha-2C adrenergic receptortarget
CeliprololCytochrome P450 2D6enzyme
DoxofyllinePhosphodiesterase 2A, cGMP-stimulatedtarget
DoxofyllineAdenosine receptor A2atarget
DoxofyllineBeta-2 adrenergic receptortarget
DoxofyllineCytochrome P450 1A2enzyme
ProtokylolBeta-2 adrenergic receptortarget
RacepinephrineAlpha-1A adrenergic receptortarget
RacepinephrineAlpha-1B adrenergic receptortarget
RacepinephrineAlpha-2A adrenergic receptortarget
RacepinephrineAlpha-2B adrenergic receptortarget
RacepinephrineAlpha-2C adrenergic receptortarget
RacepinephrineBeta-1 adrenergic receptortarget
RacepinephrineBeta-2 adrenergic receptortarget
RacepinephrineAlpha-1D adrenergic receptortarget
RacepinephrineBeta-3 adrenergic receptortarget
EtafedrineBeta-2 adrenergic receptortarget