Name
Adrenals
Accession Number
DBCAT003629
Description
Not Available
Drugs
DrugDrug Description
FlunisolideAn inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Fluticasone propionateA glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
FludrocortisoneA mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome.
HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
MometasoneA corticosteroid with no indications.
PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
TetracosactideA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Cortisone acetateA steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
CiclesonideA glucocorticoid used in the symptomatic relief of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents.
Mometasone furoateA corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus.
Drugs & Drug Targets
DrugTargetType
FlunisolideCorticosteroid-binding globulincarrier
FlunisolideGlucocorticoid receptortarget
FlunisolideCytochrome P450 3A4enzyme
Beclomethasone dipropionateCorticosteroid-binding globulincarrier
Beclomethasone dipropionateGlucocorticoid receptortarget
Beclomethasone dipropionateCytochrome P450 3A5enzyme
Beclomethasone dipropionateCytochrome P450 3A4enzyme
Beclomethasone dipropionateP-glycoprotein 1transporter
Beclomethasone dipropionateATP-binding cassette sub-family G member 2transporter
Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B1transporter
Beclomethasone dipropionateSolute carrier organic anion transporter family member 1B3transporter
BetamethasoneGlucocorticoid receptortarget
BetamethasoneCytochrome P450 3A4enzyme
BetamethasoneP-glycoprotein 1transporter
BetamethasoneCytochrome P450 19A1enzyme
BetamethasoneCytochrome P450 3A5enzyme
BetamethasoneCytochrome P450 3A7enzyme
BetamethasoneCytochrome P450 2A6enzyme
BetamethasoneCytochrome P450 1B1enzyme
BetamethasoneCytochrome P450 2B6enzyme
BetamethasoneCytochrome P450 2C8enzyme
BetamethasoneCytochrome P450 2C9enzyme
BetamethasoneCytochrome P450 2C19enzyme
BetamethasoneSerum albumincarrier
BetamethasoneCorticosteroid-binding globulincarrier
Fluticasone propionateCorticosteroid-binding globulincarrier
Fluticasone propionateCytosolic phospholipase A2target
Fluticasone propionateGlucocorticoid receptortarget
Fluticasone propionateCytochrome P450 3A4enzyme
Fluticasone propionateProgesterone receptortarget
Fluticasone propionateMineralocorticoid receptortarget
Fluticasone propionateCytochrome P450 3A5enzyme
Fluticasone propionateCytochrome P450 3A7enzyme
Fluticasone propionateCytochrome P450 2C8enzyme
Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
Fluticasone propionateP-glycoprotein 1transporter
Fluticasone propionateSolute carrier organic anion transporter family member 1B1transporter
TriamcinoloneCorticosteroid-binding globulincarrier
TriamcinoloneGlucocorticoid receptortarget
TriamcinoloneCytochrome P450 3A4enzyme
TriamcinoloneProstaglandin G/H synthase 2enzyme
TriamcinoloneCholinesteraseenzyme
TriamcinoloneCytochrome P450 3A5enzyme
TriamcinoloneCytochrome P450 3A7enzyme
TriamcinoloneSerum albumincarrier
PrednisoneGlucocorticoid receptortarget
PrednisoneCytochrome P450 3A4enzyme
PrednisoneP-glycoprotein 1transporter
PrednisoneSolute carrier organic anion transporter family member 1A2transporter
PrednisoneCytochrome P450 2C19enzyme
PrednisoneSerum albumincarrier
PrednisoneCytochrome P450 3A5enzyme
PrednisoneCorticosteroid-binding globulincarrier
PrednisoneCytochrome P450 3A Subfamilyenzyme
PrednisoneCytochrome P450 2A6enzyme
PrednisoneCytochrome P450 1B1enzyme
PrednisoneCytochrome P450 2B6enzyme
PrednisoneCytochrome P450 2C8enzyme
PrednisoneCytochrome P450 2C9enzyme
PrednisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
FludrocortisoneMineralocorticoid receptortarget
FludrocortisoneGlucocorticoid receptortarget
FludrocortisoneCytochrome P450 3A4enzyme
FludrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
FludrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
FludrocortisoneSerum albumincarrier
FludrocortisoneCorticosteroid-binding globulincarrier
HydrocortisoneAnnexin A1target
HydrocortisoneGlucocorticoid receptortarget
HydrocortisoneSex hormone-binding globulincarrier
HydrocortisoneCytochrome P450 3A4enzyme
HydrocortisoneCytochrome P450 3A5enzyme
HydrocortisoneCytochrome P450 3A7enzyme
HydrocortisoneP-glycoprotein 1transporter
HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
HydrocortisoneCytochrome P450 2C8enzyme
HydrocortisoneCorticosteroid-binding globulincarrier
HydrocortisoneSolute carrier family 22 member 8transporter
Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
HydrocortisoneCytochrome P450 2A6enzyme
HydrocortisoneCytochrome P450 1B1enzyme
HydrocortisoneCytochrome P450 2B6enzyme
HydrocortisoneCytochrome P450 2C9enzyme
HydrocortisoneCytochrome P450 2C19enzyme
MometasoneGlucocorticoid receptortarget
MometasoneCytochrome P450 2C8enzyme
MometasoneProgesterone receptortarget
MometasoneCytochrome P450 3A4enzyme
MometasoneCytochrome P450 3A5enzyme
PrednisoloneCorticosteroid-binding globulincarrier
PrednisoloneCytochrome P450 3A4enzyme
PrednisoloneGlucocorticoid receptortarget
PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
PrednisoloneP-glycoprotein 1transporter
PrednisoloneSerum albumincarrier
MethylprednisoloneGlucocorticoid receptortarget
MethylprednisoloneCytochrome P450 3A4enzyme
MethylprednisoloneP-glycoprotein 1transporter
MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
MethylprednisoloneCytochrome P450 2A6enzyme
MethylprednisoloneCytochrome P450 1B1enzyme
MethylprednisoloneCytochrome P450 2B6enzyme
MethylprednisoloneCytochrome P450 2C8enzyme
MethylprednisoloneCytochrome P450 2C9enzyme
MethylprednisoloneCytochrome P450 2C19enzyme
MethylprednisoloneAnnexin A1target
Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
MethylprednisoloneSerum albumincarrier
BudesonideGlucocorticoid receptortarget
BudesonideCytochrome P450 3A4enzyme
BudesonideCytochrome P450 3A5enzyme
BudesonideBile salt export pumptransporter
BudesonideP-glycoprotein 1transporter
BudesonideAnnexin A1target
BudesonideCytochrome P450 3A Subfamilyenzyme
BudesonideCytochrome P450 2A6enzyme
BudesonideCytochrome P450 1B1enzyme
BudesonideCytochrome P450 2B6enzyme
BudesonideCytochrome P450 2C8enzyme
BudesonideCytochrome P450 2C9enzyme
BudesonideCytochrome P450 2C19enzyme
BudesonideCorticosteroid-binding globulincarrier
BudesonideSolute carrier organic anion transporter family member 1A2transporter
BudesonideSolute carrier family 22 member 8transporter
BudesonideSerum albumincarrier
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneP-glycoprotein 1transporter
DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneATP-binding cassette sub-family G member 2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneSerum albumincarrier
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DexamethasoneSolute carrier family 22 member 8transporter
TetracosactideAdrenocorticotropic hormone receptortarget
Cortisone acetateGlucocorticoid receptortarget
Cortisone acetateCytochrome P450 3A4enzyme
Cortisone acetateCytochrome P450 3A5enzyme
CiclesonideCorticosteroid-binding globulincarrier
CiclesonideCytochrome P450 3A4enzyme
CiclesonideCytochrome P450 2D6enzyme
CiclesonideGlucocorticoid receptortarget
CiclesonideLiver carboxylesterase 1enzyme
Mometasone furoateGlucocorticoid receptortarget
Mometasone furoateCytochrome P450 2C8enzyme
Mometasone furoateProgesterone receptortarget
Mometasone furoateCytochrome P450 3A4enzyme
Mometasone furoateCytochrome P450 3A5enzyme