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Identification
NamePrednisone
Accession NumberDB00635  (APRD00340)
TypeSmall Molecule
GroupsApproved, Vet Approved
DescriptionA synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. [PubChem]
Structure
Thumb
Synonyms
1,2-Dehydrocortisone
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
Dehydrocortisone
Prednisona
Prednisonum
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Alti-prednisone Tab 5mgTablet5 mgOralAltimed Pharma Inc.1984-12-311998-08-10Canada
Deltasone 50mgTablet50 mgOralPharmacia & Upjohn Inc1972-12-312000-08-02Canada
Deltasone 5mgTablet5 mgOralPharmacia & Upjohn Inc1972-12-312000-08-02Canada
Jaa Prednisone Tab 1mg USPTablet1.0 mgOralJaapharm Canada Inc.1993-05-15Not applicableCanada
Jaa Prednisone Tab 50mg USPTablet50 mgOralJaapharm Canada Inc.1993-12-31Not applicableCanada
Jaa Prednisone Tab 5mg USPTablet5 mgOralJaapharm Canada Inc.1993-12-31Not applicableCanada
Nu-prednisoneTablet50 mgOralNu Pharm IncNot applicableNot applicableCanada
Nu-prednisoneTablet1 mgOralNu Pharm IncNot applicableNot applicableCanada
Nu-prednisoneTablet5 mgOralNu Pharm IncNot applicableNot applicableCanada
Prednisone 50 Tab 50mgTablet50 mgOralPro Doc Limitee1994-12-312016-07-18Canada
Prednisone Tab 5mgTablet5 mgOralPro Doc Limitee1959-12-31Not applicableCanada
Prednisone Tab 5mgTablet5 mgOralEverest Pharmaceuticals Ltd.1980-12-311999-07-14Canada
RayosTablet, delayed release1 mg/1OralHorizon Pharma Inc.2012-07-27Not applicableUs
RayosTablet, delayed release2 mg/1OralHorizon Pharma Inc.2012-07-27Not applicableUs
RayosTablet, delayed release5 mg/1OralHorizon Pharma Inc.2012-07-27Not applicableUs
Teva-prednisoneTablet50 mgOralTeva Canada Limited1972-12-31Not applicableCanada
Teva-prednisoneTablet5 mgOralTeva Canada Limited1967-12-31Not applicableCanada
Winpred Tab 1mgTablet1 mgOralAa Pharma Inc1978-12-31Not applicableCanada
Winpred Tab 5mgTablet5 mgOralValeant Canada Lp Valeant Canada S.E.C.1985-12-312013-07-30Canada
Approved Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Apo Prednisone Tab 1mg USPTablet1 mgOralApotex Inc1984-12-31Not applicableCanada
Apo Prednisone Tab 50mgTablet50 mgOralApotex Inc1982-12-31Not applicableCanada
Apo Prednisone Tab 5mgTablet5 mgOralApotex Inc1982-12-31Not applicableCanada
DeltasoneTablet20 mg/20mgOralOculus Innovative Sciences2009-08-03Not applicableUs
Perrigo PrednisoneTablet10 mg/1OralPerrigo Pharmaceuticals Company2006-05-19Not applicableUs
Perrigo PrednisoneTablet5 mg/1OralPerrigo Pharmaceuticals Company2006-05-19Not applicableUs
Perrigo PrednisoneTablet20 mg/1OralPerrigo Pharmaceuticals Company2006-10-11Not applicableUs
PrednisoneTablet50 mg/1OralA S Medication Solutions Llc2003-03-14Not applicableUs
PrednisoneTablet10 mg/1OralPd Rx Pharmaceuticals, Inc.2003-02-13Not applicableUs
PrednisoneTablet5 mg/1OralGolden State Medical Supply, Inc.2009-08-03Not applicableUs
PrednisoneTablet50 mg/1Oralbryant ranch prepack2003-03-14Not applicableUs
PrednisoneTablet10 mg/1OralRed Pharm Drug Inc.2002-07-12Not applicableUs
PrednisoneTablet2.5 mg/1OralDepartment Of State Health Services, Pharmacy Branch2004-12-21Not applicableUs
PrednisoneTablet5 mg/1OralRebel Distributors Corp1972-05-22Not applicableUs
PrednisoneTablet50 mg/1OralWest Ward Pharmaceuticals Corp.2003-03-14Not applicableUs
PrednisoneTablet5 mg/1OralPd Rx Pharmaceuticals, Inc.2009-08-03Not applicableUs
PrednisoneTablet20 mg/1OralPd Rx Pharmaceuticals, Inc.2001-08-29Not applicableUs
PrednisoneTablet20 mg/1OralPreferred Pharmaceuticals, Inc.2014-03-03Not applicableUs
PrednisoneTablet20 mg/1OralC.O. Truxton, Inc.2003-02-13Not applicableUs
PrednisoneTablet20 mg/1OralLake Erie Medical & Surgial Supply DBA Quality Care Products LLC1974-02-26Not applicableUs
PrednisoneTablet5 mg/1OralDIRECT RX2014-01-01Not applicableUs
PrednisoneTablet5 mg/1OralPerrigo New York Inc2006-10-02Not applicableUs
PrednisoneTablet5 mg/1OralA S Medication Solutions Llc2009-08-03Not applicableUs
PrednisoneTablet10 mg/1OralBlenheim Pharmacal, Inc.2012-12-18Not applicableUs
PrednisoneTablet20 mg/1OralREMEDYREPACK INC.2013-05-23Not applicableUs
PrednisoneTablet10 mg/201OralNorthwind Pharmaceuticals2014-04-28Not applicableUs
PrednisoneTablet5 mg/1OralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
PrednisoneTablet1 mg/1OralPhysicians Total Care, Inc.2004-10-05Not applicableUs
PrednisoneTablet5 mg/1OralHikma Pharmaceutical1972-05-22Not applicableUs
PrednisoneTablet50 mg/1OralDIRECT RX2015-01-01Not applicableUs
PrednisoneTablet5 mg/1OralMed Vantx, Inc.2002-07-12Not applicableUs
PrednisoneTablet1 mg/1OralWest ward Pharmaceutical Corp2010-11-012015-12-29Us
PrednisoneTablet10 mg/1OralPd Rx Pharmaceuticals, Inc.2009-08-03Not applicableUs
PrednisoneTablet2.5 mg/1OralWest Ward Pharmaceuticals Corp.1982-04-22Not applicableUs
PrednisoneTablet10 mg/1OralProficient Rx LP2002-07-12Not applicableUs
PrednisoneTablet2.5 mg/1OralA S Medication Solutions1982-04-22Not applicableUs
PrednisoneSolution5 mg/mLOralRoxane Laboratories, Inc.1984-11-082016-10-13Us
PrednisoneTablet10 mg/1OralREMEDYREPACK INC.2013-01-18Not applicableUs
PrednisoneTablet2.5 mg/1OralA S Medication Solutions2004-12-21Not applicableUs
PrednisoneTablet20 mg/1OralPd Rx Pharmaceuticals, Inc.1974-02-26Not applicableUs
PrednisoneTablet10 mg/1OralREMEDYREPACK INC.2013-02-28Not applicableUs
PrednisoneTablet20 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2003-02-13Not applicableUs
PrednisoneTablet5 mg/1OralActavis Pharma, Inc.1987-11-01Not applicableUs
PrednisoneTablet5 mg/1OralRebel Distributors Corp2002-07-12Not applicableUs
PrednisoneTablet1 mg/1OralWest Ward Pharmaceuticals Corp.1982-04-22Not applicableUs
PrednisoneTablet10 mg/1OralCardinal Health2003-02-13Not applicableUs
PrednisoneTablet10 mg/1OralA S Medication Solutions2002-07-12Not applicableUs
PrednisoneTablet5 mg/1OralPreferred Pharmaceuticals, Inc.2011-07-21Not applicableUs
PrednisoneTablet5 mg/1OralQualitest Pharmaceuticals2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralSTAT Rx USA LLC1974-02-26Not applicableUs
PrednisoneTablet5 mg/1OralREMEDYREPACK INC.2010-11-092016-10-13Us
PrednisoneTablet5 mg/1OralUnit Dose Services1972-04-21Not applicableUs
PrednisoneTablet10 mg/1OralBlenheim Pharmacal, Inc.2009-12-16Not applicableUs
PrednisoneTablet10 mg/1OralH.J. Harkins Company, Inc.2002-07-12Not applicableUs
PrednisoneTablet10 mg/1OralA S Medication Solutions Llc2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralClinical Solutions Wholesale2003-02-13Not applicableUs
PrednisoneTablet10 mg/1OralAmerican Health Packaging2015-08-11Not applicableUs
PrednisoneTablet10 mg/1OralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2002-07-12Not applicableUs
PrednisoneTablet10 mg/1OralKeltman Pharmaceuticals Inc.2008-07-07Not applicableUs
PrednisoneTablet1 mg/1OralDispensing Solutions, Inc.1982-04-22Not applicableUs
PrednisoneTablet5 mg/1OralSTAT Rx USA LLC2002-07-12Not applicableUs
PrednisoneTablet10 mg/1OralAse Direct, Inc.2001-08-29Not applicableUs
PrednisoneTablet10 mg/1OralREMEDYREPACK INC.2014-02-06Not applicableUs
PrednisoneTablet5 mg/1OralApotheca Inc.1972-05-22Not applicableUs
PrednisoneTablet10 mg/1OralPreferred Pharmaceuticals Inc.2016-06-17Not applicableUs
PrednisoneTablet20 mg/1OralWest Ward Pharmaceuticals Corp1974-02-262016-10-13Us
PrednisoneTablet10 mg/1OralAidarex Pharmaceuticals LLC2002-07-12Not applicableUs
PrednisoneTablet5 mg/1OralA S Medication Solutions2002-07-12Not applicableUs
PrednisoneTablet5 mg/1OralAphena Pharma Solutions Tennessee, Inc.1972-04-21Not applicableUs
PrednisoneTablet5 mg/1OralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2011-11-30Not applicableUs
PrednisoneTablet20 mg/1OralBlenheim Pharmacal, Inc.2011-06-15Not applicableUs
PrednisoneTablet10 mg/1OralREMEDYREPACK INC.2013-06-17Not applicableUs
PrednisoneTablet5 mg/1OralA S Medication Solutions Llc1972-04-21Not applicableUs
PrednisoneTablet5 mg/1OralPhysicians Total Care, Inc.2005-02-25Not applicableUs
PrednisoneTablet5 mg/1OralJUBILANT CADISTA PHARMACEUTICALS, INC.2001-08-29Not applicableUs
PrednisoneTablet10 mg/1Oralbryant ranch prepack2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralA S Medication Solutions Llc2009-08-03Not applicableUs
PrednisoneTablet20 mg/1OralBlenheim Pharmacal, Inc.2013-07-31Not applicableUs
PrednisoneTablet20 mg/1OralREMEDYREPACK INC.2013-11-12Not applicableUs
PrednisoneTablet10 mg/1OralA S Medication Solutions Llc2003-02-13Not applicableUs
PrednisoneTablet5 mg/1OralPd Rx Pharmaceuticals, Inc.2002-07-12Not applicableUs
PrednisoneTablet10 mg/1OralGolden State Medical Supply, Inc.2009-08-03Not applicableUs
PrednisoneTablet1 mg/1Oralbryant ranch prepack2004-12-21Not applicableUs
PrednisoneSolution5 mg/mLOralCarilion Materials Management1986-12-13Not applicableUs
PrednisoneTablet5 mg/1OralDepartment Of State Health Services, Pharmacy Branch2002-07-12Not applicableUs
PrednisoneTablet10 mg/1OralRebel Distributors Corp1985-12-04Not applicableUs
PrednisoneTablet1 mg/1OralCardinal Health1982-04-22Not applicableUs
PrednisoneTablet5 mg/1OralA S Medication Solutions1972-04-21Not applicableUs
PrednisoneTablet5 mg/1OralDIRECT RX2015-01-01Not applicableUs
PrednisoneTablet5 mg/1OralC.O. Truxton, Inc.1972-04-21Not applicableUs
PrednisoneTablet10 mg/1OralLake Erie Medical DBA Quality Care Products LLC1987-11-01Not applicableUs
PrednisoneTablet10 mg/1OralDIRECT RX2014-01-01Not applicableUs
PrednisoneTablet5 mg/1OralMedsource Pharmaceuticals2002-07-12Not applicableUs
PrednisoneTablet5 mg/1OralDIRECT RX2014-01-01Not applicableUs
PrednisoneTablet20 mg/1OralPd Rx Pharmaceuticals, Inc.1987-11-01Not applicableUs
PrednisoneTablet10 mg/1OralREMEDYREPACK INC.2011-09-262016-11-08Us
PrednisoneTablet2.5 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs1982-04-22Not applicableUs
PrednisoneTablet5 mg/1OralREMEDYREPACK INC.2012-08-202016-10-18Us
PrednisoneTablet10 mg/1OralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
PrednisoneTablet20 mg/1OralPhysicians Total Care, Inc.2003-08-19Not applicableUs
PrednisoneTablet10 mg/1OralHikma Pharmaceutical1985-12-04Not applicableUs
PrednisoneTablet5 mg/1OralProficient Rx LP2001-08-29Not applicableUs
PrednisoneTablet10 mg/1OralDispensing Solutions, Inc.2003-02-13Not applicableUs
PrednisoneTablet20 mg/1OralLake Erie Medical DBA Quality Care Products LLC2001-08-29Not applicableUs
PrednisoneTablet5 mg/1OralBlenheim Pharmacal, Inc.2015-05-18Not applicableUs
PrednisoneTablet20 mg/1OralWest Ward Pharmaceuticals Corp2009-08-03Not applicableUs
PrednisoneTablet5 mg/1OralProficient Rx LP2002-07-12Not applicableUs
PrednisoneTablet5 mg/1OralUnit Dose Services2001-08-29Not applicableUs
PrednisoneTablet2.5 mg/1OralWest Ward Pharmaceuticals Corp2004-01-082016-10-13Us
PrednisoneTablet10 mg/1OralREMEDYREPACK INC.2013-03-20Not applicableUs
PrednisoneTablet20 mg/1OralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2003-02-12Not applicableUs
PrednisoneTablet10 mg/1OralActavis Pharma, Inc.1987-11-01Not applicableUs
PrednisoneTablet10 mg/1OralRebel Distributors Corp2002-07-12Not applicableUs
PrednisoneTablet2.5 mg/1OralWest Ward Pharmaceuticals Corp.1982-04-22Not applicableUs
PrednisoneTablet50 mg/1OralCardinal Health2003-03-14Not applicableUs
PrednisoneTablet50 mg/1OralA S Medication Solutions2003-03-14Not applicableUs
PrednisoneTablet5 mg/1OralPreferred Pharmaceuticals, Inc.2014-04-23Not applicableUs
PrednisoneTablet10 mg/1OralQualitest Pharmaceuticals2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralPd Rx Pharmaceuticals, Inc.2003-02-12Not applicableUs
PrednisoneTablet20 mg/1OralREMEDYREPACK INC.2012-03-012016-11-22Us
PrednisoneTablet10 mg/1OralUnit Dose Services1985-12-04Not applicableUs
PrednisoneTablet20 mg/1OralBlenheim Pharmacal, Inc.2010-03-17Not applicableUs
PrednisoneTablet20 mg/1OralH.J. Harkins Company, Inc.2003-02-12Not applicableUs
PrednisoneTablet5 mg/1OralPhysicians Total Care, Inc.2002-03-12Not applicableUs
PrednisoneTablet20 mg/1OralClinical Solutions Wholesale, Llc2009-08-03Not applicableUs
PrednisoneTablet20 mg/1OralAmerican Health Packaging2015-09-01Not applicableUs
PrednisoneTablet20 mg/1Oralbryant ranch prepack2003-02-12Not applicableUs
PrednisoneTablet10 mg/1OralRed Pharm Drug Inc.1987-11-01Not applicableUs
PrednisoneTablet5 mg/1OralSTAT Rx USA LLC1972-05-22Not applicableUs
PrednisoneTablet10 mg/1OralWest Ward Pharmaceuticals Corp.2003-02-13Not applicableUs
PrednisoneTablet10 mg/1OralPd Rx Pharmaceuticals, Inc.2002-07-12Not applicableUs
PrednisoneSolution5 mg/mLOralAtlantic Biologicals Corps1986-12-13Not applicableUs
PrednisoneTablet5 mg/1OralUnit Dose Services2001-08-29Not applicableUs
PrednisoneTablet5 mg/1OralLiberty Pharmaceuticals, Inc.1987-11-01Not applicableUs
PrednisoneTablet5 mg/1OralAidarex Pharmaceuticals LLC2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralPreferred Pharmaceuticals, Inc.2015-03-26Not applicableUs
PrednisoneTablet5 mg/1OralAphena Pharma Solutions Tennessee, Llc1987-11-01Not applicableUs
PrednisoneTablet20 mg/1OralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC2011-11-30Not applicableUs
PrednisoneTablet10 mg/1OralBlenheim Pharmacal, Inc.2011-06-15Not applicableUs
PrednisoneTablet5 mg/1OralREMEDYREPACK INC.2013-07-05Not applicableUs
PrednisoneTablet10 mg/1OralA S Medication Solutions Llc2003-02-13Not applicableUs
PrednisoneTablet10 mg/1OralPhysicians Total Care, Inc.2005-02-25Not applicableUs
PrednisoneTablet10 mg/1OralJUBILANT CADISTA PHARMACEUTICALS, INC.2001-08-29Not applicableUs
PrednisoneTablet10 mg/1OralPreferred Pharmaceuticals, Inc.2011-07-21Not applicableUs
PrednisoneTablet1 mg/1OralQualitest Pharmaceuticals2004-12-21Not applicableUs
PrednisoneTablet20 mg/1OralLake Erie Medical DBA Quality Care Products LLC2003-02-13Not applicableUs
PrednisoneTablet10 mg/1OralLake Erie Medical DBA Quality Care Products LLC2010-08-11Not applicableUs
PrednisoneTablet10 mg/1OralMedsource Pharmaceuticals2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralA S Medication Solutions Llc2009-08-03Not applicableUs
PrednisoneTablet1 mg/1OralBlenheim Pharmacal, Inc.2013-11-15Not applicableUs
PrednisoneTablet10 mg/1OralREMEDYREPACK INC.2014-06-03Not applicableUs
PrednisoneTablet5 mg/1OralA S Medication Solutions Llc2002-07-12Not applicableUs
PrednisoneTablet5 mg/1OralLake Erie Medical DBA Quality Care Products LLC2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralGolden State Medical Supply, Inc.2009-08-03Not applicableUs
PrednisoneTablet2.5 mg/1Oralbryant ranch prepack2004-12-21Not applicableUs
PrednisoneTablet5 mg/1OralDispensing Solutions Inc.2008-05-29Not applicableUs
PrednisoneTablet20 mg/1OralDepartment Of State Health Services, Pharmacy Branch2003-02-13Not applicableUs
PrednisoneTablet20 mg/1OralRebel Distributors Corp1974-02-26Not applicableUs
PrednisoneSolution5 mg/mLOralWest Ward Pharmaceuticals Corp.1984-11-08Not applicableUs
PrednisoneTablet5 mg/1OralCardinal Health1972-04-21Not applicableUs
PrednisoneTablet5 mg/1OralA S Medication Solutions1972-04-21Not applicableUs
PrednisoneTablet10 mg/1OralPreferred Pharmaceuticals, Inc.2013-06-19Not applicableUs
PrednisoneTablet5 mg/1OralREMEDYREPACK INC.2016-09-01Not applicableUs
PrednisoneTablet10 mg/1OralWest Ward Pharmaceuticals Corp1985-12-042016-10-13Us
PrednisoneTablet20 mg/1OralAidarex Pharmaceuticals LLC2003-02-12Not applicableUs
PrednisoneTablet20 mg/1OralDIRECT RX2014-01-01Not applicableUs
PrednisoneTablet20 mg/1OralPd Rx Pharmaceuticals, Inc.2009-08-03Not applicableUs
PrednisoneTablet5 mg/1OralREMEDYREPACK INC.2011-12-222016-10-28Us
PrednisoneTablet10 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2003-02-13Not applicableUs
PrednisoneTablet20 mg/1OralREMEDYREPACK INC.2012-09-12Not applicableUs
PrednisoneTablet20 mg/1OralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
PrednisoneTablet10 mg/1OralPhysicians Total Care, Inc.2002-04-11Not applicableUs
PrednisoneTablet20 mg/1OralHikma Pharmaceutical1974-02-26Not applicableUs
PrednisoneTablet20 mg/1OralProficient Rx LP2009-08-03Not applicableUs
PrednisoneTablet20 mg/1OralDispensing Solutions, Inc.2003-02-12Not applicableUs
PrednisoneTablet10 mg/1OralLake Erie Medical DBA Quality Care Products LLC2001-08-29Not applicableUs
PrednisoneTablet20 mg/1OralApotheca Inc.1974-02-26Not applicableUs
PrednisoneTablet10 mg/1OralBlenheim Pharmacal, Inc.2015-05-18Not applicableUs
PrednisoneTablet10 mg/1OralWest Ward Pharmaceuticals Corp2009-08-03Not applicableUs
PrednisoneTablet20 mg/1OralMc Kesson Packaging Services A Business Unit Or Mc Kesson Corporation1987-11-01Not applicableUs
PrednisoneTablet5 mg/1OralMc Kesson Contract Packaging2011-10-12Not applicableUs
PrednisoneTablet20 mg/1OralActavis Pharma, Inc.1987-11-01Not applicableUs
PrednisoneTablet20 mg/1OralREMEDYREPACK INC.2011-12-132016-10-25Us
PrednisoneTablet5 mg/1OralWest Ward Pharmaceuticals Corp.1972-04-21Not applicableUs
PrednisoneTablet10 mg/1OralClinical Solutions Wholesale2002-07-12Not applicableUs
PrednisoneTablet5 mg/1OralA S Medication Solutions2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralREMEDYREPACK INC.2015-10-262016-10-26Us
PrednisoneTablet20 mg/1OralQualitest Pharmaceuticals2003-02-12Not applicableUs
PrednisoneTablet10 mg/1OralPd Rx Pharmaceuticals, Inc.1985-12-04Not applicableUs
PrednisoneTablet50 mg/1OralREMEDYREPACK INC.2011-11-03Not applicableUs
PrednisoneTablet20 mg/1OralUnit Dose Services1974-02-26Not applicableUs
PrednisoneTablet10 mg/1OralBlenheim Pharmacal, Inc.2013-10-03Not applicableUs
PrednisoneTablet5 mg/1OralH.J. Harkins Company, Inc.2002-07-12Not applicableUs
PrednisoneTablet10 mg/1OralPhysicians Total Care, Inc.2002-04-15Not applicableUs
PrednisoneTablet5 mg/1OralClinical Solutions Wholesale1972-04-21Not applicableUs
PrednisoneTablet5 mg/1OralSt Marys Medical Park Pharmacy2013-08-15Not applicableUs
PrednisoneTablet5 mg/1Oralbryant ranch prepack2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralRed Pharm Drug Inc.2003-02-12Not applicableUs
PrednisoneTablet10 mg/1OralSTAT Rx USA LLC2006-05-19Not applicableUs
PrednisoneTablet20 mg/1OralWest Ward Pharmaceuticals Corp.2003-02-13Not applicableUs
PrednisoneTablet20 mg/1OralPd Rx Pharmaceuticals, Inc.2009-08-03Not applicableUs
PrednisoneTablet5 mg/1OralREMEDYREPACK INC.2007-06-27Not applicableUs
PrednisoneTablet20 mg/1OralPreferred Pharmaceuticals, Inc.2011-07-21Not applicableUs
PrednisoneTablet20 mg/1OralLiberty Pharmaceuticals, Inc.2009-08-03Not applicableUs
PrednisoneTablet5 mg/1OralLake Erie Medical & Surgical Supply DBA Quality Care Products LLC1972-05-22Not applicableUs
PrednisoneTablet10 mg/1OralDIRECT RX2014-01-01Not applicableUs
PrednisoneTablet10 mg/1OralPerrigo New York Inc2006-05-19Not applicableUs
PrednisoneTablet5 mg/1OralA S Medication Solutions Llc2009-08-03Not applicableUs
PrednisoneTablet10 mg/1OralBlenheim Pharmacal, Inc.2011-07-05Not applicableUs
PrednisoneTablet10 mg/1OralREMEDYREPACK INC.2013-05-23Not applicableUs
PrednisoneTablet20 mg/1OralA S Medication Solutions Llc1974-02-26Not applicableUs
PrednisoneTablet10 mg/1OralCardinal Health2003-02-13Not applicableUs
PrednisoneTablet20 mg/1OralJUBILANT CADISTA PHARMACEUTICALS, INC.2001-08-29Not applicableUs
PrednisoneTablet20 mg/1OralCardinal Health2003-02-13Not applicableUs
PrednisoneTablet10 mg/1OralA S Medication Solutions2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralA S Medication Solutions2003-02-12Not applicableUs
PrednisoneTablet2.5 mg/1OralQualitest Pharmaceuticals2004-12-21Not applicableUs
PrednisoneTablet5 mg/1OralLake Erie Medical DBA Quality Care Products LLC1972-04-21Not applicableUs
PrednisoneTablet20 mg/1OralRed Pharm Drug, Inc.2003-02-13Not applicableUs
PrednisoneTablet20 mg/1OralSafecor Health, LLC2014-09-30Not applicableUs
PrednisoneTablet20 mg/1OralA S Medication Solutions Llc2009-08-03Not applicableUs
PrednisoneTablet20 mg/1OralBlenheim Pharmacal, Inc.2014-02-25Not applicableUs
PrednisoneTablet20 mg/1OralREMEDYREPACK INC.2014-08-01Not applicableUs
PrednisoneTablet5 mg/1OralA S Medication Solutions Llc1972-04-21Not applicableUs
PrednisoneTablet20 mg/1OralLake Erie Medical DBA Quality Care Products LLC2009-08-03Not applicableUs
PrednisoneTablet5 mg/1OralAmerican Health Packaging2015-08-11Not applicableUs
PrednisoneTablet5 mg/1OralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralKeltman Pharmaceuticals Inc.2007-04-23Not applicableUs
PrednisoneTablet10 mg/1OralDepartment Of State Health Services, Pharmacy Branch2002-07-12Not applicableUs
PrednisoneTablet1 mg/1OralRebel Distributors Corp1982-04-22Not applicableUs
PrednisoneTablet5 mg/1OralWest Ward Pharmaceuticals Corp.1972-04-21Not applicableUs
PrednisoneTablet20 mg/1OralBlenheim Pharmacal, Inc.2015-05-20Not applicableUs
PrednisoneTablet5 mg/1OralWest Ward Pharmaceuticals Corp2009-08-03Not applicableUs
PrednisoneTablet20 mg/1OralPreferred Pharmaceuticals, Inc.2013-06-19Not applicableUs
PrednisoneTablet10 mg/1OralProficient Rx LP2001-08-29Not applicableUs
PrednisoneTablet5 mg/1OralWest Ward Pharmaceuticals Corp1972-05-222016-10-13Us
PrednisoneTablet5 mg/1OralAidarex Pharmaceuticals LLC2002-07-12Not applicableUs
PrednisoneTablet5 mg/1OralA S Medication Solutions2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralPd Rx Pharmaceuticals, Inc.2009-08-03Not applicableUs
PrednisoneTablet20 mg/1OralREMEDYREPACK INC.2012-09-13Not applicableUs
PrednisoneTablet1 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs1982-04-22Not applicableUs
PrednisoneTablet5 mg/1OralREMEDYREPACK INC.2012-10-02Not applicableUs
PrednisoneTablet5 mg/1OralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
PrednisoneTablet5 mg/1OralPhysicians Total Care, Inc.2002-11-27Not applicableUs
PrednisoneTablet1 mg/1OralJUBILANT CADISTA PHARMACEUTICALS, INC.2005-06-06Not applicableUs
PrednisoneTablet50 mg/1OralProficient Rx LP2003-03-14Not applicableUs
PrednisoneTablet2.5 mg/1OralDispensing Solutions, Inc.1982-04-22Not applicableUs
PrednisoneTablet5 mg/1OralLake Erie Medical DBA Quality Care Products LLC2001-08-29Not applicableUs
PrednisoneTablet20 mg/1OralSTAT Rx USA LLC1974-02-26Not applicableUs
PrednisoneTablet20 mg/1OralDIRECT RX2015-01-01Not applicableUs
PrednisoneTablet10 mg/1OralTYA Pharmaceuticals1985-12-04Not applicableUs
PrednisoneTablet10 mg/1OralMc Kesson Contract Packaging2011-12-20Not applicableUs
PrednisoneTablet20 mg/1OralA S Medication Solutions1974-02-26Not applicableUs
PrednisoneTablet10 mg/1OralREMEDYREPACK INC.2013-02-132016-11-30Us
PrednisoneTablet1 mg/1OralWest Ward Pharmaceuticals Corp.1982-04-22Not applicableUs
PrednisoneTablet20 mg/1OralREMEDYREPACK INC.2014-10-02Not applicableUs
PrednisoneTablet10 mg/1OralA S Medication Solutions2002-07-12Not applicableUs
PrednisoneTablet20 mg/1OralA S Medication Solutions2003-02-12Not applicableUs
PrednisoneTablet5 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs1972-04-21Not applicableUs
PrednisoneTablet5 mg/1OralPd Rx Pharmaceuticals, Inc.1972-05-22Not applicableUs
PrednisoneTablet10 mg/1OralREMEDYREPACK INC.2011-08-302016-11-18Us
PrednisoneTablet20 mg/201OralNorthwind Pharmaceuticals2014-04-29Not applicableUs
PrednisoneTablet20 mg/1OralState of Florida DOH Central Pharmacy2009-07-01Not applicableUs
PrednisoneTablet50 mg/1OralPhysicians Total Care, Inc.2009-12-10Not applicableUs
PrednisoneTablet20 mg/1OralClinical Solutions Wholesale2009-08-03Not applicableUs
Prednisone IntensolSolution, concentrate5 mg/mLOralWest Ward Pharmaceuticals Corp.1985-02-20Not applicableUs
Approved Over the Counter ProductsNot Available
Unapproved/Other Products Not Available
International Brands
NameCompany
Delta-CortefUpjohn
MeticortenNot Available
OrasoneNot Available
Brand mixtures
NameLabellerIngredients
Contrast Allergy Premed PackShertech Laboratories, Llc
Metreton TabSchering Plough Canada Inc
SaltsNot Available
Categories
UNIIVB0R961HZT
CAS number53-03-2
WeightAverage: 358.4281
Monoisotopic: 358.178023942
Chemical FormulaC21H26O5
InChI KeyXOFYZVNMUHMLCC-ZPOLXVRWSA-N
InChI
InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
IUPAC Name
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-diene-5,17-dione
SMILES
[H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
Pharmacology
IndicationFor the treatment of drug-induced allergic reactions, perennial or seasonal allergic rhinitis, serum sickness, giant cell arteritis acute rheumatic or nonrheumatic carditis, systemic dermatomyositis, systemic lupus erythematosus, atopic dermatitis, contact dermatitis, exfoliative dermatitis, bullous dermatitis herpetiformis, severe seborrheic dermatitis, severe (Stevens-Johnson syndrome) erythema multiforme, mycosis fungoides, pemphigus, severe psoriasis, acute adrenocortical insufficiency, Addison's disease, secondary adrenocortical insufficiency, congenital adrenal hyperplasia, hypercalcemia associated with neoplasms, nonsuppurative thyroiditis, ulceratice colitis, Crohn's disease, acquired hemolytic anemia, congenital hypoplastic anemia, erythroblastopenia, adult secondary thrombocytopenia, adult idiopathic thrombocytopenia purpura, acute or subacute bursitis, epicondylitis, acute nonspecific tenosynovitis, acute or chronic lymphocytic leukemia, Hodgkin's or non-Hodgkin's lynphomas, Waldenstrom's macroglobulinemia, primary brain tumors (adjunct), nephrotic syndrome, tuberculous meningitis, multiple sclerosis, myasthenia gravis. cerebral edema, chorioretinitis, diffuse posterior choroiditis, aleergic conjunctivitis, Herpes zoster ophthalmicus, anterior segment inflammation, iridocyclitis, iritis, keratitis, optoc neuritis, sympathetic ophthalmia, corneal marginal allergic ulcers, symptomatic sarcoidosis, Loeffler's syndrome not manageable by other means, berylliosis, fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy and aspiration pneumonitis.
Structured Indications
PharmacodynamicsPrednisone, the most commonly-prescribed corticosteroid, is used to treat allograft rejection, asthma, systemic lupus erythematosus, and many other inflammatory states. Prednisone has some mineralocorticoid activity and thus may affect ion exchange in the kidney.
Mechanism of actionPrednisone is a glucocorticoid receptor agonist. It is first metabolized in the liver to its active form, prednisolone. Prednisolone crosses cell membranes and binds with high affinity to specific cytoplasmic receptors. The result includes inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. Prednisone can stimulate secretion of various components of gastric juice. Suppression of the production of corticotropin may lead to suppression of endogenous corticosteroids. Prednisone has slight mineralocorticoid activity, whereby entry of sodium into cells and loss of intracellular potassium is stimulated. This is particularly evident in the kidney, where rapid ion exchange leads to sodium retention and hypertension.
TargetKindPharmacological actionActionsOrganismUniProt ID
Glucocorticoid receptorProteinyes
agonist
HumanP04150 details
Corticosteroid 11-beta-dehydrogenase isozyme 1Proteinunknown
ligand
HumanP28845 details
Related Articles
AbsorptionReadily absorbed from the gastrointestinal tract. Rayos, the delayed-release formulation, has a 4-hour release time. To compare, the delayed-release formulation has a Tmax of 6.0 - 6.5 hours in healthy male subjects, whereas the immediate-release formulation has a Tmax of 2.0 hours. The rate of absorption, Cmax, and exposure is comparable between formulations.
Volume of distributionNot Available
Protein bindingExtensively bound to plasma proteins.
Metabolism

Prednisone is completely converted to the active metabolite prednisolone by 11β-hydroxysteroid dehydrogenases. It is then further metabolized mainly in the liver. The exposure of prednisolone is 4-6 fold higher than that of prednisone.

SubstrateEnzymesProduct
Prednisone
PrednisoloneDetails
Route of eliminationExcreted in the urine as sulfate and glucuronide conjugates.
Half lifeHalf life of both the immediate- and delayed- release formulation is 2 to 3 hours.
ClearanceNot Available
ToxicityNot Available
Affected organisms
  • Humans and other mammals
Pathways
PathwayCategorySMPDB ID
Prednisone Action PathwayDrug actionSMP00440
Prednisone Metabolism PathwayDrug metabolismSMP00631
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
Interactions
Drug Interactions
DrugInteractionDrug group
1,10-PhenanthrolineThe risk or severity of adverse effects can be increased when Prednisone is combined with 1,10-Phenanthroline.Experimental
AcarboseThe therapeutic efficacy of Acarbose can be decreased when used in combination with Prednisone.Approved, Investigational
AcebutololThe serum concentration of Acebutolol can be increased when it is combined with Prednisone.Approved
AceclofenacThe risk or severity of adverse effects can be increased when Aceclofenac is combined with Prednisone.Approved
AcetaminophenThe serum concentration of Prednisone can be increased when it is combined with Acetaminophen.Approved
AcetohexamideThe therapeutic efficacy of Acetohexamide can be decreased when used in combination with Prednisone.Withdrawn
AcetovanilloneThe risk or severity of adverse effects can be increased when Acetovanillone is combined with Prednisone.Investigational
AcetyldigitoxinAcetyldigitoxin may decrease the cardiotoxic activities of Prednisone.Approved
Acetylsalicylic acidThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Prednisone.Approved, Vet Approved
AdapaleneThe risk or severity of adverse effects can be increased when Adapalene is combined with Prednisone.Approved
AfatinibThe serum concentration of Afatinib can be increased when it is combined with Prednisone.Approved
AicarThe therapeutic efficacy of Aicar can be decreased when used in combination with Prednisone.Experimental
AlbendazoleThe serum concentration of Prednisone can be increased when it is combined with Albendazole.Approved, Vet Approved
AldesleukinPrednisone may decrease the antineoplastic activities of Aldesleukin.Approved
AldosteroneThe serum concentration of Prednisone can be decreased when it is combined with Aldosterone.Experimental
AlectinibThe serum concentration of Prednisone can be increased when it is combined with Alectinib.Approved
AlfentanilThe serum concentration of Prednisone can be increased when it is combined with Alfentanil.Approved, Illicit
AlitretinoinThe serum concentration of Alitretinoin can be increased when it is combined with Prednisone.Approved, Investigational
AlogliptinThe therapeutic efficacy of Alogliptin can be decreased when used in combination with Prednisone.Approved
ALT-110The risk or severity of adverse effects can be increased when Prednisone is combined with ALT-110.Investigational
Aluminum hydroxideThe bioavailability of Prednisone can be decreased when combined with Aluminum hydroxide.Approved
Aluminum phosphateThe bioavailability of Prednisone can be decreased when combined with Aluminum phosphate.Approved
AmantadineThe serum concentration of Prednisone can be increased when it is combined with Amantadine.Approved
AmbenoniumThe risk or severity of adverse effects can be increased when Prednisone is combined with Ambenonium.Approved
AmbrisentanThe serum concentration of Ambrisentan can be increased when it is combined with Prednisone.Approved, Investigational
Aminohippuric acidThe serum concentration of Prednisone can be increased when it is combined with Aminohippuric acid.Approved
Aminosalicylic AcidThe risk or severity of adverse effects can be increased when Aminosalicylic Acid is combined with Prednisone.Approved
AmiodaroneThe serum concentration of Prednisone can be increased when it is combined with Amiodarone.Approved, Investigational
AmitriptylineThe serum concentration of Prednisone can be increased when it is combined with Amitriptyline.Approved
AmlodipineThe serum concentration of Prednisone can be increased when it is combined with Amlodipine.Approved
Amphotericin BPrednisone may increase the hypokalemic activities of Amphotericin B.Approved, Investigational
AmprenavirThe serum concentration of Prednisone can be decreased when it is combined with Amprenavir.Approved
AmsacrineThe serum concentration of Prednisone can be increased when it is combined with Amsacrine.Approved
AnisodamineThe risk or severity of adverse effects can be increased when Anisodamine is combined with Prednisone.Investigational
AntipyrineThe risk or severity of adverse effects can be increased when Antipyrine is combined with Prednisone.Approved
AnvirzelAnvirzel may decrease the cardiotoxic activities of Prednisone.Investigational
ApixabanThe serum concentration of Apixaban can be increased when it is combined with Prednisone.Approved
ApremilastThe risk or severity of adverse effects can be increased when Apremilast is combined with Prednisone.Approved, Investigational
AprepitantThe serum concentration of Prednisone can be increased when it is combined with Aprepitant.Approved, Investigational
AripiprazoleThe serum concentration of Aripiprazole can be decreased when it is combined with Prednisone.Approved, Investigational
Arsenic trioxideThe serum concentration of Arsenic trioxide can be increased when it is combined with Prednisone.Approved, Investigational
AstemizoleThe serum concentration of Prednisone can be increased when it is combined with Astemizole.Approved, Withdrawn
AtazanavirThe serum concentration of Prednisone can be increased when it is combined with Atazanavir.Approved, Investigational
AtenololThe serum concentration of Prednisone can be increased when it is combined with Atenolol.Approved
AtomoxetineThe metabolism of Prednisone can be decreased when combined with Atomoxetine.Approved
AtorvastatinThe serum concentration of Prednisone can be increased when it is combined with Atorvastatin.Approved
Atracurium besylateAtracurium besylate may increase the adverse neuromuscular activities of Prednisone.Approved
AxitinibThe serum concentration of Axitinib can be increased when it is combined with Prednisone.Approved, Investigational
AzapropazoneThe risk or severity of adverse effects can be increased when Azapropazone is combined with Prednisone.Withdrawn
AzelastineThe serum concentration of Prednisone can be increased when it is combined with Azelastine.Approved
AzithromycinThe serum concentration of Prednisone can be increased when it is combined with Azithromycin.Approved
BalaglitazoneThe therapeutic efficacy of Balaglitazone can be decreased when used in combination with Prednisone.Investigational
BalsalazideThe risk or severity of adverse effects can be increased when Balsalazide is combined with Prednisone.Approved, Investigational
BazedoxifeneThe serum concentration of Prednisone can be increased when it is combined with Bazedoxifene.Approved, Investigational
BcgThe therapeutic efficacy of Bcg can be decreased when used in combination with Prednisone.Investigational
BendroflumethiazidePrednisone may increase the hypokalemic activities of Bendroflumethiazide.Approved
BenoxaprofenThe risk or severity of adverse effects can be increased when Benoxaprofen is combined with Prednisone.Withdrawn
BenzocaineThe serum concentration of Prednisone can be increased when it is combined with Benzocaine.Approved
Benzoic AcidThe therapeutic efficacy of Benzoic Acid can be decreased when used in combination with Prednisone.Approved
BepridilThe serum concentration of Prednisone can be increased when it is combined with Bepridil.Approved, Withdrawn
BetamethasoneThe serum concentration of Betamethasone can be increased when it is combined with Prednisone.Approved, Vet Approved
Betulinic AcidThe risk or severity of adverse effects can be increased when Betulinic Acid is combined with Prednisone.Investigational
BevacizumabBevacizumab may increase the cardiotoxic activities of Prednisone.Approved, Investigational
BexaroteneThe serum concentration of Prednisone can be decreased when it is combined with Bexarotene.Approved, Investigational
BiperidenThe serum concentration of Prednisone can be increased when it is combined with Biperiden.Approved
Bismuth SubcitrateThe bioavailability of Prednisone can be decreased when combined with Bismuth Subcitrate.Approved
BoceprevirThe serum concentration of Prednisone can be increased when it is combined with Boceprevir.Approved
BortezomibThe metabolism of Prednisone can be decreased when combined with Bortezomib.Approved, Investigational
BosentanThe serum concentration of Prednisone can be decreased when it is combined with Bosentan.Approved, Investigational
BosutinibThe serum concentration of Bosutinib can be increased when it is combined with Prednisone.Approved
Brentuximab vedotinThe serum concentration of Brentuximab vedotin can be increased when it is combined with Prednisone.Approved
BromfenacThe risk or severity of adverse effects can be increased when Bromfenac is combined with Prednisone.Approved
BromocriptineThe serum concentration of Prednisone can be increased when it is combined with Bromocriptine.Approved, Investigational
BucillamineThe risk or severity of adverse effects can be increased when Bucillamine is combined with Prednisone.Investigational
BuforminThe therapeutic efficacy of Buformin can be decreased when used in combination with Prednisone.Withdrawn
BumetanidePrednisone may increase the hypokalemic activities of Bumetanide.Approved
BuprenorphineThe serum concentration of Prednisone can be increased when it is combined with Buprenorphine.Approved, Illicit, Investigational, Vet Approved
BuspironeThe serum concentration of Prednisone can be increased when it is combined with Buspirone.Approved, Investigational
CabazitaxelThe risk or severity of adverse effects can be increased when Cabazitaxel is combined with Prednisone.Approved
CaffeineThe serum concentration of Prednisone can be increased when it is combined with Caffeine.Approved
CalcitriolThe therapeutic efficacy of Calcitriol can be decreased when used in combination with Prednisone.Approved, Nutraceutical
Calcium carbonateThe bioavailability of Prednisone can be decreased when combined with Calcium carbonate.Approved
CamptothecinThe serum concentration of Camptothecin can be increased when it is combined with Prednisone.Experimental
CanagliflozinThe serum concentration of Canagliflozin can be increased when it is combined with Prednisone.Approved
CandesartanThe serum concentration of Prednisone can be increased when it is combined with Candesartan.Approved
CaptoprilThe serum concentration of Prednisone can be increased when it is combined with Captopril.Approved
CarbamazepineThe serum concentration of Prednisone can be decreased when it is combined with Carbamazepine.Approved, Investigational
CarfilzomibThe serum concentration of Carfilzomib can be increased when it is combined with Prednisone.Approved
CarprofenThe risk or severity of adverse effects can be increased when Carprofen is combined with Prednisone.Approved, Vet Approved, Withdrawn
CarvedilolThe serum concentration of Prednisone can be increased when it is combined with Carvedilol.Approved, Investigational
CaspofunginThe serum concentration of Prednisone can be increased when it is combined with Caspofungin.Approved
CastanospermineThe therapeutic efficacy of Castanospermine can be decreased when used in combination with Prednisone.Experimental
CDX-110The risk or severity of adverse effects can be increased when Prednisone is combined with CDX-110.Investigational
CelecoxibThe risk or severity of adverse effects can be increased when Celecoxib is combined with Prednisone.Approved, Investigational
CeritinibThe serum concentration of Prednisone can be increased when it is combined with Ceritinib.Approved
CerivastatinThe serum concentration of Cerivastatin can be increased when it is combined with Prednisone.Withdrawn
ChloroquineThe serum concentration of Prednisone can be increased when it is combined with Chloroquine.Approved, Vet Approved
ChlorothiazidePrednisone may increase the hypokalemic activities of Chlorothiazide.Approved, Vet Approved
ChlorotrianiseneThe serum concentration of Prednisone can be increased when it is combined with Chlorotrianisene.Withdrawn
ChlorpromazineThe serum concentration of Prednisone can be increased when it is combined with Chlorpromazine.Approved, Vet Approved
ChlorpropamideThe serum concentration of Prednisone can be increased when it is combined with Chlorpropamide.Approved
ChlorprothixeneThe serum concentration of Prednisone can be increased when it is combined with Chlorprothixene.Approved, Withdrawn
ChlorthalidonePrednisone may increase the hypokalemic activities of Chlorthalidone.Approved
CholesterolThe serum concentration of Prednisone can be increased when it is combined with Cholesterol.Experimental
CholestyramineCholestyramine can cause a decrease in the absorption of Prednisone resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Cholic AcidThe serum concentration of Prednisone can be decreased when it is combined with Cholic Acid.Approved
CiglitazoneThe therapeutic efficacy of Ciglitazone can be decreased when used in combination with Prednisone.Experimental
CilazaprilThe serum concentration of Prednisone can be increased when it is combined with Cilazapril.Approved
CimetidineThe serum concentration of Prednisone can be decreased when it is combined with Cimetidine.Approved
CinoxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Cinoxacin.Approved, Withdrawn
CiprofloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Ciprofloxacin.Approved, Investigational
CisplatinThe serum concentration of Cisplatin can be increased when it is combined with Prednisone.Approved
CitalopramThe serum concentration of Prednisone can be increased when it is combined with Citalopram.Approved
ClarithromycinThe serum concentration of Prednisone can be increased when it is combined with Clarithromycin.Approved
ClemastineThe metabolism of Prednisone can be decreased when combined with Clemastine.Approved
ClobazamThe serum concentration of Clobazam can be increased when it is combined with Prednisone.Approved, Illicit
ClofazimineThe serum concentration of Prednisone can be increased when it is combined with Clofazimine.Approved, Investigational
ClomifeneThe serum concentration of Clomifene can be increased when it is combined with Prednisone.Approved, Investigational
ClomipramineThe serum concentration of Prednisone can be increased when it is combined with Clomipramine.Approved, Vet Approved
ClonidineThe serum concentration of Clonidine can be increased when it is combined with Prednisone.Approved
ClonixinThe risk or severity of adverse effects can be increased when Clonixin is combined with Prednisone.Approved
ClopidogrelThe serum concentration of Clopidogrel can be increased when it is combined with Prednisone.Approved, Nutraceutical
ClotrimazoleThe metabolism of Prednisone can be decreased when combined with Clotrimazole.Approved, Vet Approved
ClozapineThe serum concentration of Clozapine can be increased when it is combined with Prednisone.Approved
CobicistatThe serum concentration of Prednisone can be increased when it is combined with Cobicistat.Approved
CobimetinibThe serum concentration of Cobimetinib can be increased when it is combined with Prednisone.Approved
ColchicineThe serum concentration of Colchicine can be increased when it is combined with Prednisone.Approved
ColesevelamColesevelam can cause a decrease in the absorption of Prednisone resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
ColestipolColestipol can cause a decrease in the absorption of Prednisone resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
ColforsinThe serum concentration of Prednisone can be increased when it is combined with Colforsin.Experimental
ConivaptanThe serum concentration of Prednisone can be increased when it is combined with Conivaptan.Approved, Investigational
Conjugated Equine EstrogensThe serum concentration of Prednisone can be increased when it is combined with Conjugated Equine Estrogens.Approved
Corticorelin ovine triflutateThe therapeutic efficacy of Corticorelin ovine triflutate can be decreased when used in combination with Prednisone.Approved
CoumaphosThe risk or severity of adverse effects can be increased when Prednisone is combined with Coumaphos.Vet Approved
CrizotinibThe metabolism of Prednisone can be decreased when combined with Crizotinib.Approved
CurcuminThe risk or severity of adverse effects can be increased when Curcumin is combined with Prednisone.Investigational
CyclophosphamideCyclophosphamide may increase the cardiotoxic activities of Prednisone.Approved, Investigational
CyclosporineThe serum concentration of the active metabolites of Prednisone can be increased when Prednisone is used in combination with Cyclosporine.Approved, Investigational, Vet Approved
CyclosporineThe metabolism of Prednisone can be decreased when combined with Cyclosporine.Approved, Investigational, Vet Approved
D-LimoneneThe risk or severity of adverse effects can be increased when D-Limonene is combined with Prednisone.Investigational
Dabigatran etexilateThe serum concentration of the active metabolites of Dabigatran etexilate can be increased when Dabigatran etexilate is used in combination with Prednisone.Approved
DabrafenibThe serum concentration of Prednisone can be decreased when it is combined with Dabrafenib.Approved
DaclatasvirThe serum concentration of Prednisone can be increased when it is combined with Daclatasvir.Approved
DactinomycinThe serum concentration of Prednisone can be increased when it is combined with Dactinomycin.Approved
DapagliflozinThe serum concentration of Dapagliflozin can be increased when it is combined with Prednisone.Approved
DarunavirThe serum concentration of Prednisone can be increased when it is combined with Darunavir.Approved
DasatinibThe serum concentration of Prednisone can be increased when it is combined with Dasatinib.Approved, Investigational
DaunorubicinThe serum concentration of Prednisone can be decreased when it is combined with Daunorubicin.Approved
DebrisoquinThe serum concentration of Debrisoquin can be increased when it is combined with Prednisone.Approved
DecamethoniumThe risk or severity of adverse effects can be increased when Prednisone is combined with Decamethonium.Approved
DeferasiroxThe serum concentration of Prednisone can be decreased when it is combined with Deferasirox.Approved, Investigational
DelavirdineThe metabolism of Prednisone can be decreased when combined with Delavirdine.Approved
DemecariumThe risk or severity of adverse effects can be increased when Prednisone is combined with Demecarium.Approved
DenosumabThe risk or severity of adverse effects can be increased when Denosumab is combined with Prednisone.Approved
DeoxyspergualinThe therapeutic efficacy of Deoxyspergualin can be decreased when used in combination with Prednisone.Investigational
dersalazineThe risk or severity of adverse effects can be increased when dersalazine is combined with Prednisone.Investigational
DesipramineThe serum concentration of Prednisone can be increased when it is combined with Desipramine.Approved
DeslanosideDeslanoside may decrease the cardiotoxic activities of Prednisone.Approved
DesloratadineThe serum concentration of Prednisone can be increased when it is combined with Desloratadine.Approved, Investigational
DexamethasoneThe serum concentration of Prednisone can be decreased when it is combined with Dexamethasone.Approved, Investigational, Vet Approved
DextromethorphanThe serum concentration of Prednisone can be increased when it is combined with Dextromethorphan.Approved
DiazepamThe serum concentration of Diazepam can be increased when it is combined with Prednisone.Approved, Illicit, Vet Approved
DichlorvosThe risk or severity of adverse effects can be increased when Prednisone is combined with Dichlorvos.Vet Approved
DiclofenacThe serum concentration of Prednisone can be increased when it is combined with Diclofenac.Approved, Vet Approved
DienestrolThe serum concentration of Prednisone can be increased when it is combined with Dienestrol.Approved
DiethylstilbestrolThe serum concentration of Prednisone can be increased when it is combined with Diethylstilbestrol.Approved
DiflunisalThe risk or severity of adverse effects can be increased when Diflunisal is combined with Prednisone.Approved
DigitoxinDigitoxin may decrease the cardiotoxic activities of Prednisone.Approved
DigoxinDigoxin may decrease the cardiotoxic activities of Prednisone.Approved
DihydroergotamineThe metabolism of Prednisone can be decreased when combined with Dihydroergotamine.Approved
DihydrotestosteroneThe serum concentration of Dihydrotestosterone can be increased when it is combined with Prednisone.Illicit
DiltiazemThe metabolism of Prednisone can be decreased when combined with Diltiazem.Approved
DipyridamoleThe serum concentration of Prednisone can be increased when it is combined with Dipyridamole.Approved
DocetaxelThe risk or severity of adverse effects can be increased when Docetaxel is combined with Prednisone.Approved, Investigational
DomperidoneThe serum concentration of Domperidone can be increased when it is combined with Prednisone.Approved, Investigational, Vet Approved
DonepezilThe risk or severity of adverse effects can be increased when Prednisone is combined with Donepezil.Approved
DoxazosinThe serum concentration of Prednisone can be increased when it is combined with Doxazosin.Approved
DoxepinThe serum concentration of Prednisone can be increased when it is combined with Doxepin.Approved
DoxorubicinThe serum concentration of Doxorubicin can be increased when it is combined with Prednisone.Approved, Investigational
DoxorubicinThe serum concentration of Prednisone can be decreased when it is combined with Doxorubicin.Approved, Investigational
DoxycyclineThe metabolism of Prednisone can be decreased when combined with Doxycycline.Approved, Investigational, Vet Approved
DronabinolThe serum concentration of Prednisone can be increased when it is combined with Dronabinol.Approved, Illicit
DronedaroneThe metabolism of Prednisone can be decreased when combined with Dronedarone.Approved
DroxicamThe risk or severity of adverse effects can be increased when Droxicam is combined with Prednisone.Approved
DulaglutideThe therapeutic efficacy of Dulaglutide can be decreased when used in combination with Prednisone.Approved
DuvelisibThe risk or severity of adverse effects can be increased when Duvelisib is combined with Prednisone.Investigational
E6201The risk or severity of adverse effects can be increased when E6201 is combined with Prednisone.Investigational
EbselenThe risk or severity of adverse effects can be increased when Ebselen is combined with Prednisone.Investigational
EchothiophateThe risk or severity of adverse effects can be increased when Prednisone is combined with Echothiophate.Approved
EdoxabanThe serum concentration of Edoxaban can be increased when it is combined with Prednisone.Approved
EdrophoniumThe risk or severity of adverse effects can be increased when Prednisone is combined with Edrophonium.Approved
EfavirenzThe serum concentration of Prednisone can be decreased when it is combined with Efavirenz.Approved, Investigational
ElbasvirThe serum concentration of Prednisone can be increased when it is combined with Elbasvir.Approved
EletriptanThe serum concentration of Eletriptan can be increased when it is combined with Prednisone.Approved, Investigational
EmpagliflozinThe therapeutic efficacy of Empagliflozin can be decreased when used in combination with Prednisone.Approved
EnalaprilThe serum concentration of Prednisone can be increased when it is combined with Enalapril.Approved, Vet Approved
EnoxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Enoxacin.Approved
EnzalutamideThe serum concentration of Prednisone can be decreased when it is combined with Enzalutamide.Approved
EpinastineThe serum concentration of Epinastine can be increased when it is combined with Prednisone.Approved, Investigational
EpirizoleThe risk or severity of adverse effects can be increased when Epirizole is combined with Prednisone.Approved
ErgonovineThe serum concentration of Prednisone can be increased when it is combined with Ergonovine.Approved
ErgotamineThe serum concentration of Prednisone can be increased when it is combined with Ergotamine.Approved
ErlotinibThe serum concentration of Erlotinib can be increased when it is combined with Prednisone.Approved, Investigational
ErythromycinThe metabolism of Prednisone can be decreased when combined with Erythromycin.Approved, Vet Approved
Eslicarbazepine acetateThe serum concentration of Prednisone can be decreased when it is combined with Eslicarbazepine acetate.Approved
EstradiolThe serum concentration of Prednisone can be increased when it is combined with Estradiol.Approved, Investigational, Vet Approved
EstramustineThe serum concentration of Prednisone can be increased when it is combined with Estramustine.Approved
EstriolThe serum concentration of Prednisone can be increased when it is combined with Estriol.Approved, Vet Approved
EstroneThe serum concentration of Prednisone can be increased when it is combined with Estrone.Approved
Etacrynic acidPrednisone may increase the hypokalemic activities of Etacrynic acid.Approved
EtanerceptThe risk or severity of adverse effects can be increased when Etanercept is combined with Prednisone.Approved, Investigational
Ethinyl EstradiolThe serum concentration of Prednisone can be increased when it is combined with Ethinyl Estradiol.Approved
EtodolacThe risk or severity of adverse effects can be increased when Etodolac is combined with Prednisone.Approved, Investigational, Vet Approved
EtofenamateThe risk or severity of adverse effects can be increased when Etofenamate is combined with Prednisone.Approved
EtoposideThe serum concentration of Prednisone can be increased when it is combined with Etoposide.Approved
EtoricoxibThe risk or severity of adverse effects can be increased when Etoricoxib is combined with Prednisone.Approved, Investigational
EtravirineThe serum concentration of Prednisone can be decreased when it is combined with Etravirine.Approved
Evening primrose oilThe risk or severity of adverse effects can be increased when Evening primrose oil is combined with Prednisone.Approved
EverolimusThe serum concentration of Everolimus can be increased when it is combined with Prednisone.Approved
ExenatideThe therapeutic efficacy of Exenatide can be decreased when used in combination with Prednisone.Approved, Investigational
exisulindThe risk or severity of adverse effects can be increased when exisulind is combined with Prednisone.Investigational
EzetimibeThe serum concentration of Ezetimibe can be increased when it is combined with Prednisone.Approved
FelodipineThe serum concentration of Prednisone can be increased when it is combined with Felodipine.Approved, Investigational
FenbufenThe risk or severity of adverse effects can be increased when Fenbufen is combined with Prednisone.Approved
FenoprofenThe risk or severity of adverse effects can be increased when Fenoprofen is combined with Prednisone.Approved
FentanylThe serum concentration of Prednisone can be increased when it is combined with Fentanyl.Approved, Illicit, Investigational, Vet Approved
FenthionThe risk or severity of adverse effects can be increased when Prednisone is combined with Fenthion.Vet Approved
FesoterodineThe serum concentration of Fesoterodine can be increased when it is combined with Prednisone.Approved
FexofenadineThe serum concentration of Prednisone can be increased when it is combined with Fexofenadine.Approved
FidaxomicinThe serum concentration of Fidaxomicin can be increased when it is combined with Prednisone.Approved
FingolimodPrednisone may increase the immunosuppressive activities of Fingolimod.Approved, Investigational
FleroxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Fleroxacin.Approved
FloctafenineThe risk or severity of adverse effects can be increased when Floctafenine is combined with Prednisone.Approved, Withdrawn
FluconazoleThe serum concentration of Prednisone can be increased when it is combined with Fluconazole.Approved
FlumequineThe risk or severity of adverse effects can be increased when Prednisone is combined with Flumequine.Withdrawn
FlunixinThe risk or severity of adverse effects can be increased when Flunixin is combined with Prednisone.Vet Approved
FluoxetineThe serum concentration of Prednisone can be increased when it is combined with Fluoxetine.Approved, Vet Approved
FluoxymesteronePrednisone may increase the fluid retaining activities of Fluoxymesterone.Approved, Illicit
FlupentixolThe serum concentration of Prednisone can be increased when it is combined with Flupentixol.Approved, Withdrawn
FluphenazineThe serum concentration of Prednisone can be increased when it is combined with Fluphenazine.Approved
FlurazepamThe serum concentration of Prednisone can be increased when it is combined with Flurazepam.Approved, Illicit
FlurbiprofenThe risk or severity of adverse effects can be increased when Flurbiprofen is combined with Prednisone.Approved, Investigational
Fluticasone furoateThe serum concentration of Fluticasone furoate can be increased when it is combined with Prednisone.Approved
FluvoxamineThe metabolism of Prednisone can be decreased when combined with Fluvoxamine.Approved, Investigational
FosamprenavirThe metabolism of Prednisone can be decreased when combined with Fosamprenavir.Approved
FosaprepitantThe serum concentration of Prednisone can be increased when it is combined with Fosaprepitant.Approved
FosphenytoinThe serum concentration of Prednisone can be decreased when it is combined with Fosphenytoin.Approved
FurosemidePrednisone may increase the hypokalemic activities of Furosemide.Approved, Vet Approved
Fusidic AcidThe serum concentration of Prednisone can be increased when it is combined with Fusidic Acid.Approved
G17DTThe risk or severity of adverse effects can be increased when Prednisone is combined with G17DT.Investigational
GalantamineThe risk or severity of adverse effects can be increased when Prednisone is combined with Galantamine.Approved
Gallamine TriethiodideThe risk or severity of adverse effects can be increased when Prednisone is combined with Gallamine Triethiodide.Approved
GarenoxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Garenoxacin.Investigational
GatifloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Gatifloxacin.Approved, Investigational
GefitinibThe serum concentration of Gefitinib can be increased when it is combined with Prednisone.Approved, Investigational
GemcitabineThe serum concentration of Gemcitabine can be increased when it is combined with Prednisone.Approved
GemifloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Gemifloxacin.Approved, Investigational
GenisteinThe serum concentration of Prednisone can be increased when it is combined with Genistein.Investigational
GI-5005The risk or severity of adverse effects can be increased when Prednisone is combined with GI-5005.Investigational
Ginkgo bilobaThe risk or severity of adverse effects can be increased when Prednisone is combined with Ginkgo biloba.Approved, Nutraceutical
GlibornurideThe therapeutic efficacy of Glibornuride can be decreased when used in combination with Prednisone.Withdrawn
GliclazideThe therapeutic efficacy of Gliclazide can be decreased when used in combination with Prednisone.Approved
GlimepirideThe therapeutic efficacy of Glimepiride can be decreased when used in combination with Prednisone.Approved
GlipizideThe therapeutic efficacy of Glipizide can be decreased when used in combination with Prednisone.Approved
GliquidoneThe therapeutic efficacy of Gliquidone can be decreased when used in combination with Prednisone.Approved
GlyburideThe serum concentration of Prednisone can be increased when it is combined with Glyburide.Approved
GlycerolThe serum concentration of Prednisone can be increased when it is combined with Glycerol.Experimental
Glycerol PhenylbutyrateThe therapeutic efficacy of Glycerol Phenylbutyrate can be decreased when used in combination with Prednisone.Approved
Gramicidin DThe serum concentration of Prednisone can be increased when it is combined with Gramicidin D.Approved
GrazoprevirThe serum concentration of Grazoprevir can be increased when it is combined with Prednisone.Approved
GrepafloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Grepafloxacin.Withdrawn
GusperimusThe therapeutic efficacy of Gusperimus can be decreased when used in combination with Prednisone.Investigational
HaloperidolThe serum concentration of Prednisone can be increased when it is combined with Haloperidol.Approved
HexestrolThe serum concentration of Prednisone can be increased when it is combined with Hexestrol.Withdrawn
HigenamineThe risk or severity of adverse effects can be increased when Higenamine is combined with Prednisone.Investigational
HMPL-004The risk or severity of adverse effects can be increased when HMPL-004 is combined with Prednisone.Investigational
Huperzine AThe risk or severity of adverse effects can be increased when Prednisone is combined with Huperzine A.Investigational
HyaluronidaseThe therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Prednisone.Approved, Investigational
HydrochlorothiazidePrednisone may increase the hypokalemic activities of Hydrochlorothiazide.Approved, Vet Approved
HydrocodoneThe serum concentration of Hydrocodone can be decreased when it is combined with Prednisone.Approved, Illicit
HydrocortisoneThe serum concentration of Prednisone can be increased when it is combined with Hydrocortisone.Approved, Vet Approved
HydroflumethiazidePrednisone may increase the hypokalemic activities of Hydroflumethiazide.Approved
IbuprofenThe serum concentration of Ibuprofen can be increased when it is combined with Prednisone.Approved
IbuproxamThe risk or severity of adverse effects can be increased when Ibuproxam is combined with Prednisone.Withdrawn
IcatibantThe risk or severity of adverse effects can be increased when Icatibant is combined with Prednisone.Approved
IdelalisibThe serum concentration of Prednisone can be increased when it is combined with Idelalisib.Approved
ImatinibThe metabolism of Prednisone can be decreased when combined with Imatinib.Approved
ImipramineThe serum concentration of Prednisone can be increased when it is combined with Imipramine.Approved
IndacaterolIndacaterol may increase the hypokalemic activities of Prednisone.Approved
IndapamidePrednisone may increase the hypokalemic activities of Indapamide.Approved
IndinavirThe serum concentration of Prednisone can be increased when it is combined with Indinavir.Approved
IndomethacinThe serum concentration of Prednisone can be increased when it is combined with Indomethacin.Approved, Investigational
IndoprofenThe risk or severity of adverse effects can be increased when Indoprofen is combined with Prednisone.Withdrawn
INGN 201The risk or severity of adverse effects can be increased when Prednisone is combined with INGN 201.Investigational
INGN 225The risk or severity of adverse effects can be increased when Prednisone is combined with INGN 225.Investigational
Insulin AspartThe therapeutic efficacy of Insulin Aspart can be decreased when used in combination with Prednisone.Approved
Insulin DetemirThe therapeutic efficacy of Insulin Detemir can be decreased when used in combination with Prednisone.Approved
Insulin GlargineThe therapeutic efficacy of Insulin Glargine can be decreased when used in combination with Prednisone.Approved
Insulin GlulisineThe therapeutic efficacy of Insulin Glulisine can be decreased when used in combination with Prednisone.Approved
Insulin LisproThe therapeutic efficacy of Insulin Lispro can be decreased when used in combination with Prednisone.Approved
Insulin PorkThe therapeutic efficacy of Insulin Pork can be decreased when used in combination with Prednisone.Approved
IrinotecanThe serum concentration of Irinotecan can be increased when it is combined with Prednisone.Approved, Investigational
IsavuconazoniumThe metabolism of Prednisone can be decreased when combined with Isavuconazonium.Approved, Investigational
IsoflurophateThe risk or severity of adverse effects can be increased when Prednisone is combined with Isoflurophate.Approved, Withdrawn
IsoniazidThe serum concentration of Isoniazid can be decreased when it is combined with Prednisone.Approved
IsoxicamThe risk or severity of adverse effects can be increased when Isoxicam is combined with Prednisone.Withdrawn
IsradipineThe metabolism of Prednisone can be decreased when combined with Isradipine.Approved
ItraconazoleThe serum concentration of Prednisone can be increased when it is combined with Itraconazole.Approved, Investigational
IvacaftorThe serum concentration of Prednisone can be increased when it is combined with Ivacaftor.Approved
IvermectinThe serum concentration of Prednisone can be increased when it is combined with Ivermectin.Approved, Vet Approved
KebuzoneThe risk or severity of adverse effects can be increased when Kebuzone is combined with Prednisone.Experimental
KetamineThe serum concentration of Prednisone can be increased when it is combined with Ketamine.Approved, Vet Approved
KetazolamThe serum concentration of Ketazolam can be increased when it is combined with Prednisone.Approved
KetoconazoleThe serum concentration of Prednisone can be increased when it is combined with Ketoconazole.Approved, Investigational
KetoprofenThe risk or severity of adverse effects can be increased when Ketoprofen is combined with Prednisone.Approved, Vet Approved
KetorolacThe risk or severity of adverse effects can be increased when Ketorolac is combined with Prednisone.Approved
LamivudineThe serum concentration of Lamivudine can be increased when it is combined with Prednisone.Approved, Investigational
LamotrigineThe serum concentration of Lamotrigine can be increased when it is combined with Prednisone.Approved, Investigational
LansoprazoleThe serum concentration of Prednisone can be increased when it is combined with Lansoprazole.Approved, Investigational
LapatinibThe serum concentration of Prednisone can be increased when it is combined with Lapatinib.Approved, Investigational
LedipasvirThe serum concentration of Ledipasvir can be increased when it is combined with Prednisone.Approved
LeflunomideThe risk or severity of adverse effects can be increased when Prednisone is combined with Leflunomide.Approved, Investigational
LenalidomideThe serum concentration of Lenalidomide can be increased when it is combined with Prednisone.Approved
LenvatinibThe serum concentration of Lenvatinib can be increased when it is combined with Prednisone.Approved
LevetiracetamThe serum concentration of Levetiracetam can be increased when it is combined with Prednisone.Approved, Investigational
LevofloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Levofloxacin.Approved, Investigational
LevomilnacipranThe serum concentration of Levomilnacipran can be increased when it is combined with Prednisone.Approved
LevothyroxineThe serum concentration of Prednisone can be decreased when it is combined with Levothyroxine.Approved
LidocaineThe serum concentration of Prednisone can be increased when it is combined with Lidocaine.Approved, Vet Approved
LinagliptinThe serum concentration of Linagliptin can be increased when it is combined with Prednisone.Approved
LiothyronineThe serum concentration of Prednisone can be decreased when it is combined with Liothyronine.Approved, Vet Approved
LiotrixThe serum concentration of Prednisone can be decreased when it is combined with Liotrix.Approved
LiraglutideThe therapeutic efficacy of Liraglutide can be decreased when used in combination with Prednisone.Approved
LisinoprilThe serum concentration of Prednisone can be increased when it is combined with Lisinopril.Approved, Investigational
LisofyllineThe risk or severity of adverse effects can be increased when Lisofylline is combined with Prednisone.Investigational
LomefloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Lomefloxacin.Approved
LomitapideThe serum concentration of Prednisone can be increased when it is combined with Lomitapide.Approved
LoperamideThe serum concentration of Prednisone can be increased when it is combined with Loperamide.Approved
LopinavirThe serum concentration of Prednisone can be increased when it is combined with Lopinavir.Approved
LoratadineThe serum concentration of Prednisone can be increased when it is combined with Loratadine.Approved
LornoxicamThe risk or severity of adverse effects can be increased when Lornoxicam is combined with Prednisone.Approved
LosartanThe serum concentration of Prednisone can be increased when it is combined with Losartan.Approved
LovastatinThe metabolism of Prednisone can be decreased when combined with Lovastatin.Approved, Investigational
LoxoprofenThe risk or severity of adverse effects can be increased when Loxoprofen is combined with Prednisone.Approved
LuliconazoleThe serum concentration of Prednisone can be increased when it is combined with Luliconazole.Approved
LumacaftorThe serum concentration of Prednisone can be decreased when it is combined with Lumacaftor.Approved
LumiracoxibThe risk or severity of adverse effects can be increased when Lumiracoxib is combined with Prednisone.Approved, Investigational
MagaldrateThe bioavailability of Prednisone can be decreased when combined with Magaldrate.Withdrawn
Magnesium carbonateThe bioavailability of Prednisone can be decreased when combined with Magnesium carbonate.Approved
Magnesium hydroxideThe bioavailability of Prednisone can be decreased when combined with Magnesium hydroxide.Approved
Magnesium oxideThe bioavailability of Prednisone can be decreased when combined with Magnesium oxide.Approved
Magnesium salicylateThe risk or severity of adverse effects can be increased when Magnesium salicylate is combined with Prednisone.Approved
Magnesium TrisilicateThe bioavailability of Prednisone can be decreased when combined with Magnesium Trisilicate.Approved
MalathionThe risk or severity of adverse effects can be increased when Prednisone is combined with Malathion.Approved, Investigational
MannitolThe serum concentration of Mannitol can be increased when it is combined with Prednisone.Approved, Investigational
MaprotilineThe serum concentration of Prednisone can be increased when it is combined with Maprotiline.Approved
MasoprocolThe risk or severity of adverse effects can be increased when Masoprocol is combined with Prednisone.Approved
MebendazoleThe serum concentration of Prednisone can be increased when it is combined with Mebendazole.Approved, Vet Approved
Meclofenamic acidThe risk or severity of adverse effects can be increased when Meclofenamic acid is combined with Prednisone.Approved, Vet Approved
Mefenamic acidThe risk or severity of adverse effects can be increased when Mefenamic acid is combined with Prednisone.Approved
MefloquineThe serum concentration of Prednisone can be increased when it is combined with Mefloquine.Approved
Megestrol acetateThe serum concentration of Prednisone can be increased when it is combined with Megestrol acetate.Approved, Vet Approved
MeloxicamThe risk or severity of adverse effects can be increased when Meloxicam is combined with Prednisone.Approved, Vet Approved
MemantineThe risk or severity of adverse effects can be increased when Prednisone is combined with Memantine.Approved, Investigational
MeprobamateThe serum concentration of Prednisone can be increased when it is combined with Meprobamate.Approved, Illicit
MesalazineThe risk or severity of adverse effects can be increased when Mesalazine is combined with Prednisone.Approved
MestranolThe serum concentration of Prednisone can be increased when it is combined with Mestranol.Approved
MetamizoleThe risk or severity of adverse effects can be increased when Metamizole is combined with Prednisone.Withdrawn
MetforminThe therapeutic efficacy of Metformin can be decreased when used in combination with Prednisone.Approved
MethadoneThe serum concentration of Prednisone can be increased when it is combined with Methadone.Approved
MethallenestrilThe serum concentration of Prednisone can be increased when it is combined with Methallenestril.Experimental
Methanesulfonyl FluorideThe risk or severity of adverse effects can be increased when Prednisone is combined with Methanesulfonyl Fluoride.Investigational
MethotrexateThe serum concentration of Methotrexate can be increased when it is combined with Prednisone.Approved
MethyclothiazidePrednisone may increase the hypokalemic activities of Methyclothiazide.Approved
MethylprednisoloneThe serum concentration of Methylprednisolone can be increased when it is combined with Prednisone.Approved, Vet Approved
MethyltestosteronePrednisone may increase the fluid retaining activities of Methyltestosterone.Approved
MetolazonePrednisone may increase the hypokalemic activities of Metolazone.Approved
MetoprololThe serum concentration of Prednisone can be increased when it is combined with Metoprolol.Approved, Investigational
MibefradilThe serum concentration of Prednisone can be increased when it is combined with Mibefradil.Withdrawn
MiconazoleThe serum concentration of Prednisone can be increased when it is combined with Miconazole.Approved, Investigational, Vet Approved
MidazolamThe serum concentration of Prednisone can be decreased when it is combined with Midazolam.Approved, Illicit
MifepristoneThe therapeutic efficacy of Prednisone can be decreased when used in combination with Mifepristone.Approved, Investigational
MiglitolThe therapeutic efficacy of Miglitol can be decreased when used in combination with Prednisone.Approved
MiglustatThe therapeutic efficacy of Miglustat can be decreased when used in combination with Prednisone.Approved
MinaprineThe risk or severity of adverse effects can be increased when Prednisone is combined with Minaprine.Approved
MirabegronThe serum concentration of Mirabegron can be increased when it is combined with Prednisone.Approved
MitiglinideThe therapeutic efficacy of Mitiglinide can be decreased when used in combination with Prednisone.Approved, Investigational
MitomycinThe serum concentration of Prednisone can be increased when it is combined with Mitomycin.Approved
MitotaneThe serum concentration of Prednisone can be decreased when it is combined with Mitotane.Approved
MitoxantroneThe serum concentration of Prednisone can be decreased when it is combined with Mitoxantrone.Approved, Investigational
MivacuriumMivacurium may increase the adverse neuromuscular activities of Prednisone.Approved
MizoribineThe risk or severity of adverse effects can be increased when Mizoribine is combined with Prednisone.Investigational
ModafinilThe serum concentration of Prednisone can be decreased when it is combined with Modafinil.Approved, Investigational
MorphineThe serum concentration of Prednisone can be increased when it is combined with Morphine.Approved, Investigational
MoxifloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Moxifloxacin.Approved, Investigational
Mycophenolate mofetilThe serum concentration of Mycophenolate mofetil can be increased when it is combined with Prednisone.Approved, Investigational
Mycophenolic acidThe risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Prednisone.Approved
NabumetoneThe risk or severity of adverse effects can be increased when Nabumetone is combined with Prednisone.Approved
NadololThe serum concentration of Nadolol can be increased when it is combined with Prednisone.Approved
NafamostatThe risk or severity of adverse effects can be increased when Nafamostat is combined with Prednisone.Investigational
NafcillinThe serum concentration of Prednisone can be decreased when it is combined with Nafcillin.Approved
NaftifineThe risk or severity of adverse effects can be increased when Naftifine is combined with Prednisone.Approved
Nalidixic AcidThe risk or severity of adverse effects can be increased when Prednisone is combined with Nalidixic Acid.Approved
NaloxegolThe serum concentration of Naloxegol can be increased when it is combined with Prednisone.Approved
NaloxoneThe serum concentration of Naloxone can be increased when it is combined with Prednisone.Approved, Vet Approved
NaltrexoneThe serum concentration of Prednisone can be increased when it is combined with Naltrexone.Approved, Investigational, Vet Approved
NaproxenThe risk or severity of adverse effects can be increased when Naproxen is combined with Prednisone.Approved, Vet Approved
NaringeninThe serum concentration of Prednisone can be increased when it is combined with Naringenin.Experimental
NatalizumabThe risk or severity of adverse effects can be increased when Prednisone is combined with Natalizumab.Approved, Investigational
NateglinideThe therapeutic efficacy of Nateglinide can be decreased when used in combination with Prednisone.Approved, Investigational
NCX 4016The risk or severity of adverse effects can be increased when NCX 4016 is combined with Prednisone.Investigational
NefazodoneThe serum concentration of Prednisone can be increased when it is combined with Nefazodone.Approved, Withdrawn
NelfinavirThe serum concentration of Prednisone can be increased when it is combined with Nelfinavir.Approved
NemonoxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Nemonoxacin.Investigational
NeostigmineThe serum concentration of Prednisone can be increased when it is combined with Neostigmine.Approved, Vet Approved
NepafenacThe risk or severity of adverse effects can be increased when Nepafenac is combined with Prednisone.Approved
NetupitantThe serum concentration of Prednisone can be increased when it is combined with Netupitant.Approved
NevirapineThe serum concentration of Prednisone can be decreased when it is combined with Nevirapine.Approved
NicardipineThe serum concentration of Prednisone can be increased when it is combined with Nicardipine.Approved
NicorandilThe risk or severity of adverse effects can be increased when Prednisone is combined with Nicorandil.Approved
NifedipineThe serum concentration of Prednisone can be decreased when it is combined with Nifedipine.Approved
Niflumic AcidThe risk or severity of adverse effects can be increased when Niflumic Acid is combined with Prednisone.Approved
NilotinibThe metabolism of Prednisone can be decreased when combined with Nilotinib.Approved, Investigational
NimesulideThe risk or severity of adverse effects can be increased when Nimesulide is combined with Prednisone.Approved, Withdrawn
NimodipineThe serum concentration of Nimodipine can be decreased when it is combined with Prednisone.Approved
NintedanibThe serum concentration of Nintedanib can be increased when it is combined with Prednisone.Approved
NisoldipineThe serum concentration of Prednisone can be increased when it is combined with Nisoldipine.Approved
NitrazepamThe serum concentration of Prednisone can be increased when it is combined with Nitrazepam.Approved
NitrendipineThe serum concentration of Prednisone can be increased when it is combined with Nitrendipine.Approved
NitroaspirinThe risk or severity of adverse effects can be increased when Nitroaspirin is combined with Prednisone.Investigational
NizatidineThe serum concentration of Nizatidine can be increased when it is combined with Prednisone.Approved
NorethisteroneThe serum concentration of Prednisone can be decreased when it is combined with Norethisterone.Approved
NorfloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Norfloxacin.Approved
OfloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Ofloxacin.Approved
OlanzapineThe serum concentration of Olanzapine can be increased when it is combined with Prednisone.Approved, Investigational
OlaparibThe metabolism of Prednisone can be decreased when combined with Olaparib.Approved
OlopatadineThe risk or severity of adverse effects can be increased when Olopatadine is combined with Prednisone.Approved
OlsalazineThe risk or severity of adverse effects can be increased when Olsalazine is combined with Prednisone.Approved
OmbitasvirThe serum concentration of Ombitasvir can be increased when it is combined with Prednisone.Approved
OmeprazoleThe serum concentration of Prednisone can be increased when it is combined with Omeprazole.Approved, Investigational, Vet Approved
OrgoteinThe risk or severity of adverse effects can be increased when Orgotein is combined with Prednisone.Vet Approved
OsimertinibThe serum concentration of Prednisone can be increased when it is combined with Osimertinib.Approved
OuabainOuabain may decrease the cardiotoxic activities of Prednisone.Approved
OxandrolonePrednisone may increase the fluid retaining activities of Oxandrolone.Approved, Investigational
OxaprozinThe risk or severity of adverse effects can be increased when Oxaprozin is combined with Prednisone.Approved
OxymetholonePrednisone may increase the fluid retaining activities of Oxymetholone.Approved, Illicit
OxyphenbutazoneThe risk or severity of adverse effects can be increased when Oxyphenbutazone is combined with Prednisone.Withdrawn
P-NitrophenolThe serum concentration of Prednisone can be increased when it is combined with P-Nitrophenol.Experimental
PaclitaxelThe risk or severity of adverse effects can be increased when Paclitaxel is combined with Prednisone.Approved, Vet Approved
PalbociclibThe serum concentration of Prednisone can be increased when it is combined with Palbociclib.Approved
Palmitic AcidThe serum concentration of Prednisone can be increased when it is combined with Palmitic Acid.Experimental
PanobinostatThe serum concentration of Panobinostat can be increased when it is combined with Prednisone.Approved, Investigational
PantoprazoleThe serum concentration of Prednisone can be increased when it is combined with Pantoprazole.Approved
ParecoxibThe risk or severity of adverse effects can be increased when Parecoxib is combined with Prednisone.Approved
ParoxetineThe serum concentration of Prednisone can be increased when it is combined with Paroxetine.Approved, Investigational
PazopanibThe serum concentration of Pazopanib can be increased when it is combined with Prednisone.Approved
PazufloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Pazufloxacin.Investigational
PefloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Pefloxacin.Approved
PentobarbitalThe serum concentration of Prednisone can be decreased when it is combined with Pentobarbital.Approved, Vet Approved
PerindoprilThe serum concentration of Prednisone can be increased when it is combined with Perindopril.Approved
PhenforminThe therapeutic efficacy of Phenformin can be decreased when used in combination with Prednisone.Approved, Withdrawn
PhenobarbitalThe serum concentration of Prednisone can be decreased when it is combined with Phenobarbital.Approved
Phenylacetic acidThe therapeutic efficacy of Phenylacetic acid can be decreased when used in combination with Prednisone.Approved
PhenylbutazoneThe risk or severity of adverse effects can be increased when Phenylbutazone is combined with Prednisone.Approved, Vet Approved
PhenytoinThe serum concentration of Prednisone can be decreased when it is combined with Phenytoin.Approved, Vet Approved
PhysostigmineThe risk or severity of adverse effects can be increased when Prednisone is combined with Physostigmine.Approved
PimecrolimusThe risk or severity of adverse effects can be increased when Pimecrolimus is combined with Prednisone.Approved, Investigational
PimozideThe serum concentration of Prednisone can be increased when it is combined with Pimozide.Approved
PioglitazoneThe therapeutic efficacy of Pioglitazone can be decreased when used in combination with Prednisone.Approved, Investigational
PiretanidePrednisone may increase the hypokalemic activities of Piretanide.Experimental
PirfenidoneThe risk or severity of adverse effects can be increased when Pirfenidone is combined with Prednisone.Investigational
PiroxicamThe risk or severity of adverse effects can be increased when Piroxicam is combined with Prednisone.Approved, Investigational
PitavastatinThe serum concentration of Pitavastatin can be increased when it is combined with Prednisone.Approved
Platelet Activating FactorThe serum concentration of Prednisone can be decreased when it is combined with Platelet Activating Factor.Experimental
Polyestradiol phosphateThe serum concentration of Prednisone can be increased when it is combined with Polyestradiol phosphate.Approved
PolythiazidePrednisone may increase the hypokalemic activities of Polythiazide.Approved
PomalidomideThe serum concentration of Pomalidomide can be increased when it is combined with Prednisone.Approved
PonatinibThe serum concentration of Ponatinib can be increased when it is combined with Prednisone.Approved
PosaconazoleThe serum concentration of Prednisone can be increased when it is combined with Posaconazole.Approved, Investigational, Vet Approved
PramlintideThe therapeutic efficacy of Pramlintide can be decreased when used in combination with Prednisone.Approved, Investigational
PravastatinThe serum concentration of Pravastatin can be increased when it is combined with Prednisone.Approved
PrazosinThe serum concentration of Prednisone can be increased when it is combined with Prazosin.Approved
PrednisoloneThe serum concentration of Prednisolone can be increased when it is combined with Prednisone.Approved, Vet Approved
PrimidoneThe serum concentration of Prednisone can be decreased when it is combined with Primidone.Approved, Vet Approved
ProbenecidThe serum concentration of Prednisone can be increased when it is combined with Probenecid.Approved
ProgesteroneThe serum concentration of Prednisone can be decreased when it is combined with Progesterone.Approved, Vet Approved
PromestrieneThe serum concentration of Prednisone can be increased when it is combined with Promestriene.Investigational
PromethazineThe serum concentration of Prednisone can be increased when it is combined with Promethazine.Approved
PropacetamolThe risk or severity of adverse effects can be increased when Propacetamol is combined with Prednisone.Approved
PropafenoneThe serum concentration of Prednisone can be increased when it is combined with Propafenone.Approved
PropranololThe serum concentration of Prednisone can be increased when it is combined with Propranolol.Approved, Investigational
ProtriptylineThe serum concentration of Prednisone can be increased when it is combined with Protriptyline.Approved
PrucaloprideThe serum concentration of Prucalopride can be increased when it is combined with Prednisone.Approved
PrulifloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Prulifloxacin.Investigational
PTC299The risk or severity of adverse effects can be increased when PTC299 is combined with Prednisone.Investigational
PyridostigmineThe risk or severity of adverse effects can be increased when Prednisone is combined with Pyridostigmine.Approved
QuercetinThe serum concentration of Prednisone can be increased when it is combined with Quercetin.Experimental
QuetiapineThe serum concentration of Quetiapine can be increased when it is combined with Prednisone.Approved
QuinacrineThe serum concentration of Prednisone can be increased when it is combined with Quinacrine.Approved
QuinestrolThe serum concentration of Prednisone can be increased when it is combined with Quinestrol.Approved
QuinethazonePrednisone may increase the hypokalemic activities of Quinethazone.Approved
QuinidineThe serum concentration of Prednisone can be increased when it is combined with Quinidine.Approved
QuinineThe serum concentration of Prednisone can be increased when it is combined with Quinine.Approved
Rabies vaccineThe risk or severity of adverse effects can be increased when Prednisone is combined with Rabies vaccine.Approved
Rabies vaccineThe therapeutic efficacy of Rabies vaccine can be decreased when used in combination with Prednisone.Approved
RanitidineThe serum concentration of Prednisone can be increased when it is combined with Ranitidine.Approved
RanolazineThe serum concentration of Ranolazine can be increased when it is combined with Prednisone.Approved, Investigational
RapacuroniumRapacuronium may increase the adverse neuromuscular activities of Prednisone.Withdrawn
ReboxetineThe serum concentration of Prednisone can be increased when it is combined with Reboxetine.Approved, Investigational
RegorafenibThe serum concentration of Prednisone can be increased when it is combined with Regorafenib.Approved
RepaglinideThe therapeutic efficacy of Repaglinide can be decreased when used in combination with Prednisone.Approved, Investigational
ReserpineThe serum concentration of Prednisone can be decreased when it is combined with Reserpine.Approved
ResveratrolThe risk or severity of adverse effects can be increased when Resveratrol is combined with Prednisone.Experimental, Investigational
RifabutinThe serum concentration of Prednisone can be decreased when it is combined with Rifabutin.Approved
RifampicinThe serum concentration of Prednisone can be decreased when it is combined with Rifampicin.Approved
RifapentineThe serum concentration of Prednisone can be decreased when it is combined with Rifapentine.Approved
RifaximinThe serum concentration of Rifaximin can be increased when it is combined with Prednisone.Approved, Investigational
RilpivirineThe serum concentration of Prednisone can be increased when it is combined with Rilpivirine.Approved
RisperidoneThe serum concentration of Risperidone can be increased when it is combined with Prednisone.Approved, Investigational
RitonavirThe serum concentration of Prednisone can be increased when it is combined with Ritonavir.Approved, Investigational
RivaroxabanThe serum concentration of Rivaroxaban can be increased when it is combined with Prednisone.Approved
RivastigmineThe risk or severity of adverse effects can be increased when Prednisone is combined with Rivastigmine.Approved, Investigational
RofecoxibThe risk or severity of adverse effects can be increased when Rofecoxib is combined with Prednisone.Investigational, Withdrawn
RoflumilastRoflumilast may increase the immunosuppressive activities of Prednisone.Approved
RolapitantThe serum concentration of Prednisone can be increased when it is combined with Rolapitant.Approved
RomidepsinThe serum concentration of Romidepsin can be increased when it is combined with Prednisone.Approved, Investigational
RosiglitazoneThe therapeutic efficacy of Rosiglitazone can be decreased when used in combination with Prednisone.Approved, Investigational
RosoxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Rosoxacin.Approved
S EquolThe serum concentration of Prednisone can be increased when it is combined with S Equol.Investigational
SalicylamideThe risk or severity of adverse effects can be increased when Salicylamide is combined with Prednisone.Approved
Salicylic acidThe serum concentration of Salicylic acid can be increased when it is combined with Prednisone.Approved, Vet Approved
SalsalateThe risk or severity of adverse effects can be increased when Salsalate is combined with Prednisone.Approved
SaquinavirThe serum concentration of Prednisone can be increased when it is combined with Saquinavir.Approved, Investigational
SaxagliptinThe serum concentration of Saxagliptin can be decreased when it is combined with Prednisone.Approved
ScopolamineThe serum concentration of Prednisone can be increased when it is combined with Scopolamine.Approved
SecoisolariciresinolThe serum concentration of Prednisone can be increased when it is combined with Secoisolariciresinol.Investigational
SelegilineThe serum concentration of Prednisone can be increased when it is combined with Selegiline.Approved, Investigational, Vet Approved
SelexipagThe serum concentration of Selexipag can be increased when it is combined with Prednisone.Approved
SeratrodastThe risk or severity of adverse effects can be increased when Seratrodast is combined with Prednisone.Approved, Investigational
SertralineThe serum concentration of Prednisone can be increased when it is combined with Sertraline.Approved
SildenafilThe metabolism of Prednisone can be decreased when combined with Sildenafil.Approved, Investigational
SilodosinThe serum concentration of Silodosin can be increased when it is combined with Prednisone.Approved
SiltuximabThe serum concentration of Prednisone can be decreased when it is combined with Siltuximab.Approved
SimeprevirThe serum concentration of Prednisone can be increased when it is combined with Simeprevir.Approved
SimvastatinThe serum concentration of Prednisone can be increased when it is combined with Simvastatin.Approved
Sipuleucel-TThe therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Prednisone.Approved
SirolimusThe serum concentration of Prednisone can be decreased when it is combined with Sirolimus.Approved, Investigational
SitagliptinThe serum concentration of Sitagliptin can be increased when it is combined with Prednisone.Approved, Investigational
Sodium phenylbutyrateThe therapeutic efficacy of Sodium phenylbutyrate can be decreased when used in combination with Prednisone.Approved
SofosbuvirThe serum concentration of Sofosbuvir can be increased when it is combined with Prednisone.Approved
Somatropin recombinantThe therapeutic efficacy of Prednisone can be decreased when used in combination with Somatropin recombinant.Approved, Investigational
SorafenibThe serum concentration of Sorafenib can be increased when it is combined with Prednisone.Approved, Investigational
SparfloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Sparfloxacin.Approved
SphingosineThe serum concentration of Sphingosine can be increased when it is combined with Prednisone.Experimental
SpironolactoneThe serum concentration of Prednisone can be increased when it is combined with Spironolactone.Approved
SRP 299The risk or severity of adverse effects can be increased when Prednisone is combined with SRP 299.Investigational
SRT501The risk or severity of adverse effects can be increased when SRT501 is combined with Prednisone.Investigational
St. John's WortThe serum concentration of Prednisone can be decreased when it is combined with St. John's Wort.Nutraceutical
StanozololPrednisone may increase the fluid retaining activities of Stanozolol.Approved, Vet Approved
StaurosporineThe serum concentration of Prednisone can be increased when it is combined with Staurosporine.Experimental
StiripentolThe serum concentration of Prednisone can be increased when it is combined with Stiripentol.Approved
StreptozocinThe serum concentration of Prednisone can be decreased when it is combined with Streptozocin.Approved
SulfasalazineThe risk or severity of adverse effects can be increased when Sulfasalazine is combined with Prednisone.Approved
SulfinpyrazoneThe serum concentration of Prednisone can be increased when it is combined with Sulfinpyrazone.Approved
SulfisoxazoleThe metabolism of Prednisone can be decreased when combined with Sulfisoxazole.Approved, Vet Approved
SulindacThe risk or severity of adverse effects can be increased when Sulindac is combined with Prednisone.Approved
SulodexideThe therapeutic efficacy of Sulodexide can be decreased when used in combination with Prednisone.Approved, Investigational
SumatriptanThe serum concentration of Prednisone can be increased when it is combined with Sumatriptan.Approved, Investigational
SunitinibThe serum concentration of Prednisone can be increased when it is combined with Sunitinib.Approved, Investigational
SuprofenThe risk or severity of adverse effects can be increased when Suprofen is combined with Prednisone.Approved, Withdrawn
Synthetic Conjugated Estrogens, AThe serum concentration of Prednisone can be increased when it is combined with Synthetic Conjugated Estrogens, A.Approved
Synthetic Conjugated Estrogens, BThe serum concentration of Prednisone can be increased when it is combined with Synthetic Conjugated Estrogens, B.Approved
TacrineThe serum concentration of Prednisone can be increased when it is combined with Tacrine.Withdrawn
TacrolimusThe risk or severity of adverse effects can be increased when Tacrolimus is combined with Prednisone.Approved, Investigational
TacrolimusThe serum concentration of Prednisone can be decreased when it is combined with Tacrolimus.Approved, Investigational
TamoxifenThe serum concentration of Prednisone can be decreased when it is combined with Tamoxifen.Approved
Taurocholic AcidThe serum concentration of Prednisone can be increased when it is combined with Taurocholic Acid.Experimental
Technetium Tc-99m sestamibiThe serum concentration of Technetium Tc-99m sestamibi can be increased when it is combined with Prednisone.Approved
TelaprevirThe serum concentration of Telaprevir can be decreased when it is combined with Prednisone.Approved
TelithromycinThe serum concentration of Prednisone can be increased when it is combined with Telithromycin.Approved
TelmisartanThe serum concentration of Prednisone can be increased when it is combined with Telmisartan.Approved, Investigational
TemafloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Temafloxacin.Withdrawn
TemsirolimusThe serum concentration of Temsirolimus can be increased when it is combined with Prednisone.Approved
TenoxicamThe risk or severity of adverse effects can be increased when Tenoxicam is combined with Prednisone.Approved
TepoxalinThe risk or severity of adverse effects can be increased when Tepoxalin is combined with Prednisone.Vet Approved
TerazosinThe serum concentration of Prednisone can be increased when it is combined with Terazosin.Approved
TerfenadineThe serum concentration of Prednisone can be increased when it is combined with Terfenadine.Withdrawn
TeriflunomideThe risk or severity of adverse effects can be increased when Teriflunomide is combined with Prednisone.Approved
TesamorelinThe serum concentration of the active metabolites of Prednisone can be reduced when Prednisone is used in combination with Tesamorelin resulting in a loss in efficacy.Approved, Investigational
TesmilifeneThe serum concentration of Prednisone can be decreased when it is combined with Tesmilifene.Investigational
TestosteroneThe serum concentration of Prednisone can be increased when it is combined with Testosterone.Approved, Investigational
TG4010The risk or severity of adverse effects can be increased when Prednisone is combined with TG4010.Investigational
ThiazolidinedioneThe therapeutic efficacy of Thiazolidinedione can be decreased when used in combination with Prednisone.Investigational
Tiaprofenic acidThe risk or severity of adverse effects can be increased when Tiaprofenic acid is combined with Prednisone.Approved
TiboloneThe serum concentration of Prednisone can be increased when it is combined with Tibolone.Approved
TicagrelorThe serum concentration of Ticagrelor can be increased when it is combined with Prednisone.Approved
TiclopidineThe metabolism of Prednisone can be decreased when combined with Ticlopidine.Approved
TimololThe serum concentration of Timolol can be increased when it is combined with Prednisone.Approved
TinoridineThe risk or severity of adverse effects can be increased when Tinoridine is combined with Prednisone.Investigational
TocilizumabThe serum concentration of Prednisone can be decreased when it is combined with Tocilizumab.Approved
TofacitinibPrednisone may increase the immunosuppressive activities of Tofacitinib.Approved, Investigational
TolazamideThe therapeutic efficacy of Tolazamide can be decreased when used in combination with Prednisone.Approved
TolbutamideThe therapeutic efficacy of Tolbutamide can be decreased when used in combination with Prednisone.Approved
Tolfenamic AcidThe risk or severity of adverse effects can be increased when Tolfenamic Acid is combined with Prednisone.Approved
TolmetinThe risk or severity of adverse effects can be increased when Tolmetin is combined with Prednisone.Approved
TolvaptanThe serum concentration of Tolvaptan can be increased when it is combined with Prednisone.Approved
TopotecanThe serum concentration of Topotecan can be increased when it is combined with Prednisone.Approved, Investigational
TorasemidePrednisone may increase the hypokalemic activities of Torasemide.Approved
ToremifeneThe serum concentration of Toremifene can be increased when it is combined with Prednisone.Approved, Investigational
TranilastThe risk or severity of adverse effects can be increased when Tranilast is combined with Prednisone.Approved, Investigational
TrastuzumabTrastuzumab may increase the cardiotoxic activities of Prednisone.Approved, Investigational
Trastuzumab emtansineThe serum concentration of Trastuzumab emtansine can be increased when it is combined with Prednisone.Approved
TrazodoneThe serum concentration of Prednisone can be decreased when it is combined with Trazodone.Approved, Investigational
TrichlorfonThe risk or severity of adverse effects can be increased when Prednisone is combined with Trichlorfon.Vet Approved
TrichlormethiazidePrednisone may increase the hypokalemic activities of Trichlormethiazide.Approved, Vet Approved
TrifluoperazineThe serum concentration of Prednisone can be increased when it is combined with Trifluoperazine.Approved
TriflupromazineThe serum concentration of Prednisone can be increased when it is combined with Triflupromazine.Approved, Vet Approved
TrimethoprimThe serum concentration of Prednisone can be decreased when it is combined with Trimethoprim.Approved, Vet Approved
TrimipramineThe serum concentration of Prednisone can be increased when it is combined with Trimipramine.Approved
Trisalicylate-cholineThe risk or severity of adverse effects can be increased when Trisalicylate-choline is combined with Prednisone.Approved
TroglitazoneThe therapeutic efficacy of Troglitazone can be decreased when used in combination with Prednisone.Withdrawn
TroleandomycinThe serum concentration of Prednisone can be increased when it is combined with Troleandomycin.Approved
TrovafloxacinThe risk or severity of adverse effects can be increased when Prednisone is combined with Trovafloxacin.Approved, Withdrawn
TubocurarineThe risk or severity of adverse effects can be increased when Prednisone is combined with Tubocurarine.Approved
UlipristalThe serum concentration of Ulipristal can be increased when it is combined with Prednisone.Approved
UmeclidiniumThe serum concentration of Umeclidinium can be increased when it is combined with Prednisone.Approved
ValdecoxibThe risk or severity of adverse effects can be increased when Valdecoxib is combined with Prednisone.Investigational, Withdrawn
VecuroniumThe serum concentration of Vecuronium can be increased when it is combined with Prednisone.Approved
VenetoclaxThe serum concentration of Venetoclax can be increased when it is combined with Prednisone.Approved
VenlafaxineThe metabolism of Prednisone can be decreased when combined with Venlafaxine.Approved
VerapamilThe metabolism of Prednisone can be decreased when combined with Verapamil.Approved
VildagliptinThe therapeutic efficacy of Vildagliptin can be decreased when used in combination with Prednisone.Approved, Investigational
VinblastineThe serum concentration of Prednisone can be decreased when it is combined with Vinblastine.Approved
VincristineThe serum concentration of Vincristine can be increased when it is combined with Prednisone.Approved, Investigational
VincristineThe serum concentration of Prednisone can be decreased when it is combined with Vincristine.Approved, Investigational
VinorelbineThe serum concentration of Prednisone can be increased when it is combined with Vinorelbine.Approved, Investigational
VismodegibThe serum concentration of Vismodegib can be increased when it is combined with Prednisone.Approved
VogliboseThe therapeutic efficacy of Voglibose can be decreased when used in combination with Prednisone.Approved, Investigational
VoriconazoleThe serum concentration of Prednisone can be increased when it is combined with Voriconazole.Approved, Investigational
WarfarinPrednisone may increase the anticoagulant activities of Warfarin.Approved
ZaltoprofenThe risk or severity of adverse effects can be increased when Zaltoprofen is combined with Prednisone.Approved
ZeranolThe serum concentration of Prednisone can be increased when it is combined with Zeranol.Vet Approved
ZidovudineThe serum concentration of Zidovudine can be increased when it is combined with Prednisone.Approved
ZileutonThe risk or severity of adverse effects can be increased when Zileuton is combined with Prednisone.Approved, Investigational, Withdrawn
ZimelidineThe serum concentration of Prednisone can be increased when it is combined with Zimelidine.Withdrawn
ZiprasidoneThe metabolism of Prednisone can be decreased when combined with Ziprasidone.Approved
ZomepiracThe risk or severity of adverse effects can be increased when Zomepirac is combined with Prednisone.Withdrawn
Food Interactions
  • Avoid alcohol.
  • Avoid taking with grapefruit juice.
  • Take with food to reduce irritation.
  • When Rayos, the delayed-release tablet, is taken without food, Cmax and bioavailability were lower compared to the fed state.
References
Synthesis Reference

Jean Buendia, Michel Vivat, “Process for the production of prednisone 17.21-diacylates.” U.S. Patent US4601854, issued May, 1982.

US4601854
General ReferencesNot Available
External Links
ATC CodesH02AB07A07EA03
AHFS Codes
  • 68:04.00
PDB EntriesNot Available
FDA labelNot Available
MSDSDownload (132 KB)
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9918
Blood Brain Barrier+0.9383
Caco-2 permeable-0.5096
P-glycoprotein substrateSubstrate0.7861
P-glycoprotein inhibitor INon-inhibitor0.7847
P-glycoprotein inhibitor IINon-inhibitor0.8383
Renal organic cation transporterNon-inhibitor0.7463
CYP450 2C9 substrateNon-substrate0.8496
CYP450 2D6 substrateNon-substrate0.9138
CYP450 3A4 substrateSubstrate0.7407
CYP450 1A2 substrateNon-inhibitor0.9406
CYP450 2C9 inhibitorNon-inhibitor0.9072
CYP450 2D6 inhibitorNon-inhibitor0.9418
CYP450 2C19 inhibitorNon-inhibitor0.9253
CYP450 3A4 inhibitorNon-inhibitor0.8902
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9095
Ames testNon AMES toxic0.9132
CarcinogenicityNon-carcinogens0.9597
BiodegradationNot ready biodegradable0.925
Rat acute toxicity1.8914 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.95
hERG inhibition (predictor II)Non-inhibitor0.584
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Schering corp sub schering plough corp
  • Roxane laboratories inc
  • Wockhardt eu operations (swiss) ag
  • Muro pharmaceutical inc
  • Halsey drug co inc
  • Bayer pharmaceuticals corp
  • Pharmacia and upjohn co
  • Ferndale laboratories inc
  • Solvay pharmaceuticals
  • Parke davis div warner lambert co
  • Schwarz pharma inc
  • American therapeutics inc
  • Amneal pharmaceuticals ny llc
  • Cm bundy co
  • Cadista pharmaceuticals inc
  • Contract pharmacal corp
  • Duramed pharmaceuticals inc sub barr laboratories inc
  • Elkins sinn div ah robins co inc
  • Everylife
  • John j ferrante
  • Heather drug co inc
  • Impax laboratories inc
  • Inwood laboratories inc sub forest laboratories inc
  • Ivax pharmaceuticals inc sub teva pharmaceuticals usa
  • Kv pharmaceutical co
  • Lannett co inc
  • Lederle laboratories div american cyanamid co
  • Marshall pharmacal corp
  • Mutual pharmaceutical co inc
  • Nylos trading co inc
  • Panray corp sub ormont drug and chemical co inc
  • L perrigo co
  • Pharmavite pharmaceuticals
  • Phoenix laboratories inc
  • Purepac pharmaceutical co
  • Private formulations inc
  • Rexall drug co
  • Sandoz inc
  • Scherer laboratories inc
  • Sperti drug products inc
  • Superpharm corp
  • Teva pharmaceuticals usa inc
  • Udl laboratories inc
  • Upsher smith laboratories inc
  • Valeant pharmaceuticals international
  • Vangard laboratories inc div midway medical co
  • Vintage pharmaceuticals inc
  • Vitarine pharmaceuticals inc
  • Watson laboratories inc
  • West ward pharmaceutical corp
  • Whiteworth towne paulsen inc
Packagers
Dosage forms
FormRouteStrength
Kit
TabletOral20 mg/20mg
TabletOral1.0 mg
TabletOral50 mg
TabletOral5 mg
TabletOral
SolutionOral5 mg/mL
TabletOral1 mg/1
TabletOral10 mg/1
TabletOral10 mg/201
TabletOral2.5 mg/1
TabletOral20 mg/201
TabletOral20 mg/1
TabletOral5 mg/1
TabletOral50 mg/1
Solution, concentrateOral5 mg/mL
Tablet, delayed releaseOral1 mg/1
Tablet, delayed releaseOral2 mg/1
Tablet, delayed releaseOral5 mg/1
TabletOral1 mg
Prices
Unit descriptionCostUnit
Sterapred DS 21 10 mg tablet Disp Pack64.0USD disp
Prednisone powder3.36USD g
Sterapred ds 10 mg tablet unipak2.93USD tablet
Prednisone 5 mg/ml solution1.17USD ml
PredniSONE 5 mg/5ml Solution0.5USD ml
Prednisone 50 mg tablet0.47USD tablet
Prednisone 20 mg tablet0.29USD tablet
Prednisone 10 mg tablet0.27USD tablet
Prednisone 2.5 mg tablet0.25USD tablet
Prednisone 1 mg tablet0.23USD tablet
Apo-Prednisone 50 mg Tablet0.18USD tablet
Winpred 1 mg Tablet0.12USD tablet
Apo-Prednisone 1 mg Tablet0.11USD tablet
Prednisone 5 mg tablet0.08USD tablet
Apo-Prednisone 5 mg Tablet0.04USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US6488960 No2000-03-142020-03-14Us
US6677326 No2000-03-142020-03-14Us
US8168218 No2008-01-072028-01-07Us
US8309124 No2004-04-232024-04-23Us
US8394407 No2004-04-232024-04-23Us
US9040085 No2004-04-232024-04-23Us
US9186332 No2004-04-232024-04-23Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point230 - 235 °C (decomposes)MSDS
water solubilityVery slightly solubleMSDS
logP1.46MSDS
Predicted Properties
PropertyValueSource
Water Solubility0.111 mg/mLALOGPS
logP2.07ALOGPS
logP1.66ChemAxon
logS-3.5ALOGPS
pKa (Strongest Acidic)12.58ChemAxon
pKa (Strongest Basic)-3.3ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count5ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area91.67 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity97.57 m3·mol-1ChemAxon
Polarizability38.17 Å3ChemAxon
Number of Rings4ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Download (12.5 KB)
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, PositiveNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, NegativeNot Available
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, NegativeNot Available
MSMass Spectrum (Electron Ionization)splash10-05fs-2951000000-1a9b3a7e18f6088d28dbView in MoNA
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as 21-hydroxysteroids. These are steroids carrying a hydroxyl group at the 21-position of the steroid backbone.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassSteroids and steroid derivatives
Sub ClassHydroxysteroids
Direct Parent21-hydroxysteroids
Alternative Parents
Substituents
  • 21-hydroxysteroid
  • Progestogin-skeleton
  • Pregnane-skeleton
  • 20-oxosteroid
  • 17-hydroxysteroid
  • Oxosteroid
  • 11-oxosteroid
  • 3-oxosteroid
  • 3-oxo-delta-1,4-steroid
  • Delta-1,4-steroid
  • Cyclohexanone
  • Tertiary alcohol
  • Cyclic alcohol
  • Alpha-hydroxy ketone
  • Cyclic ketone
  • Ketone
  • Hydrocarbon derivative
  • Primary alcohol
  • Organooxygen compound
  • Carbonyl group
  • Alcohol
  • Aliphatic homopolycyclic compound
Molecular FrameworkAliphatic homopolycyclic compounds
External Descriptors

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
agonist
General Function:
Zinc ion binding
Specific Function:
Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon grow...
Gene Name:
NR3C1
Uniprot ID:
P04150
Molecular Weight:
85658.57 Da
References
  1. Liu BG, Li ZY, Du M: [Effects of jingui shenqi pill combined prednisone on expression of glucocorticoid receptor and its clinical effect in treating bullous pemphigoid patients]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Oct;26(10):881-4. [PubMed:17121036 ]
  2. Friel PN, Alexander T, Wright JV: Suppression of adrenal function by low-dose prednisone: assessment with 24-hour urinary steroid hormone profiles--a review of five cases. Altern Med Rev. 2006 Mar;11(1):40-6. [PubMed:16597193 ]
  3. Diez JJ, Iglesias P: Pharmacological therapy of Cushing's syndrome: drugs and indications. Mini Rev Med Chem. 2007 May;7(5):467-80. [PubMed:17504182 ]
  4. Yano A, Fujii Y, Iwai A, Kawakami S, Kageyama Y, Kihara K: Glucocorticoids suppress tumor lymphangiogenesis of prostate cancer cells. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6012-7. [PubMed:17062674 ]
  5. Yano A, Fujii Y, Iwai A, Kageyama Y, Kihara K: Glucocorticoids suppress tumor angiogenesis and in vivo growth of prostate cancer cells. Clin Cancer Res. 2006 May 15;12(10):3003-9. [PubMed:16707595 ]
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
ligand
General Function:
11-beta-hydroxysteroid dehydrogenase [nad(p)] activity
Specific Function:
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity).
Gene Name:
HSD11B1
Uniprot ID:
P28845
Molecular Weight:
32400.665 Da
References
  1. Raza K, Hardy R, Cooper MS: The 11beta-hydroxysteroid dehydrogenase enzymes--arbiters of the effects of glucocorticoids in synovium and bone. Rheumatology (Oxford). 2010 Nov;49(11):2016-23. doi: 10.1093/rheumatology/keq212. Epub 2010 Jul 15. [PubMed:20634231 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrateinhibitorinducer
General Function:
Vitamin d3 25-hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiot...
Gene Name:
CYP3A4
Uniprot ID:
P08684
Molecular Weight:
57342.67 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inducer
General Function:
Steroid hydroxylase activity
Specific Function:
Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.
Gene Name:
CYP2C19
Uniprot ID:
P33261
Molecular Weight:
55930.545 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]

Carriers

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Toxic substance binding
Specific Function:
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
Gene Name:
ALB
Uniprot ID:
P02768
Molecular Weight:
69365.94 Da
References
  1. Ferry JJ, Wagner JG: The nonlinear pharmacokinetics of prednisone and prednisolone. II. Plasma protein binding of prednisone and prednisolone in rabbit and human plasma. Biopharm Drug Dispos. 1987 May-Jun;8(3):261-72. [PubMed:3593903 ]

Transporters

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrateinhibitor
General Function:
Xenobiotic-transporting atpase activity
Specific Function:
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Gene Name:
ABCB1
Uniprot ID:
P08183
Molecular Weight:
141477.255 Da
References
  1. Nagy H, Goda K, Fenyvesi F, Bacso Z, Szilasi M, Kappelmayer J, Lustyik G, Cianfriglia M, Szabo G Jr: Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochem Biophys Res Commun. 2004 Mar 19;315(4):942-9. [PubMed:14985103 ]
  2. Yates CR, Chang C, Kearbey JD, Yasuda K, Schuetz EG, Miller DD, Dalton JT, Swaan PW: Structural determinants of P-glycoprotein-mediated transport of glucocorticoids. Pharm Res. 2003 Nov;20(11):1794-803. [PubMed:14661924 ]
  3. Dilger K, Schwab M, Fromm MF: Identification of budesonide and prednisone as substrates of the intestinal drug efflux pump P-glycoprotein. Inflamm Bowel Dis. 2004 Sep;10(5):578-83. [PubMed:15472518 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin.
Gene Name:
SLCO1A2
Uniprot ID:
P46721
Molecular Weight:
74144.105 Da
References
  1. Bossuyt X, Muller M, Hagenbuch B, Meier PJ: Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver. J Pharmacol Exp Ther. 1996 Mar;276(3):891-6. [PubMed:8786566 ]
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Drug created on June 13, 2005 07:24 / Updated on December 04, 2016 02:45