Indiplon

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Indiplon
Accession Number
DB12590
Type
Small Molecule
Groups
Investigational
Description

Indiplon has been used in trials studying the treatment of Insomnia and Depression.

Structure
Thumb
Synonyms
Not Available
External IDs
NBI-34060
Categories
UNII
8BT63DA42E
CAS number
325715-02-4
Weight
Average: 376.43
Monoisotopic: 376.099396945
Chemical Formula
C20H16N4O2S
InChI Key
CBIAWPMZSFFRGN-UHFFFAOYSA-N
InChI
InChI=1S/C20H16N4O2S/c1-13(25)23(2)15-6-3-5-14(11-15)17-8-9-21-20-16(12-22-24(17)20)19(26)18-7-4-10-27-18/h3-12H,1-2H3
IUPAC Name
N-methyl-N-{3-[3-(thiophene-2-carbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl}acetamide
SMILES
CN(C(C)=O)C1=CC=CC(=C1)C1=CC=NC2=C(C=NN12)C(=O)C1=CC=CS1

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with Indiplon.Experimental
AcepromazineThe risk or severity of adverse effects can be increased when Acepromazine is combined with Indiplon.Approved, Vet Approved
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with Indiplon.Approved
AdipiplonThe risk or severity of adverse effects can be increased when Adipiplon is combined with Indiplon.Investigational
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Indiplon.Approved, Investigational
AlaproclateThe risk or severity of adverse effects can be increased when Indiplon is combined with Alaproclate.Experimental
AlfaxaloneThe risk or severity of adverse effects can be increased when Alfaxalone is combined with Indiplon.Vet Approved
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Indiplon.Approved, Illicit
AllopregnanoloneThe risk or severity of adverse effects can be increased when Allopregnanolone is combined with Indiplon.Investigational
AlphacetylmethadolThe risk or severity of adverse effects can be increased when Alphacetylmethadol is combined with Indiplon.Experimental, Illicit
AlphaprodineThe risk or severity of adverse effects can be increased when Indiplon is combined with Alphaprodine.Illicit
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Indiplon.Approved, Illicit, Investigational
AmisulprideThe risk or severity of adverse effects can be increased when Amisulpride is combined with Indiplon.Approved, Investigational
AmitriptylineThe risk or severity of adverse effects can be increased when Amitriptyline is combined with Indiplon.Approved
AmobarbitalThe risk or severity of adverse effects can be increased when Amobarbital is combined with Indiplon.Approved, Illicit
AmoxapineThe risk or severity of adverse effects can be increased when Amoxapine is combined with Indiplon.Approved
AmperozideThe risk or severity of adverse effects can be increased when Amperozide is combined with Indiplon.Experimental
AripiprazoleThe risk or severity of adverse effects can be increased when Aripiprazole is combined with Indiplon.Approved, Investigational
ArticaineThe risk or severity of adverse effects can be increased when Articaine is combined with Indiplon.Approved
AsenapineThe risk or severity of adverse effects can be increased when Asenapine is combined with Indiplon.Approved
AzaperoneThe risk or severity of adverse effects can be increased when Azaperone is combined with Indiplon.Investigational, Vet Approved
AzelastineIndiplon may increase the central nervous system depressant (CNS depressant) activities of Azelastine.Approved
BaclofenThe risk or severity of adverse effects can be increased when Baclofen is combined with Indiplon.Approved
BarbitalThe risk or severity of adverse effects can be increased when Barbital is combined with Indiplon.Illicit
BenperidolThe risk or severity of adverse effects can be increased when Indiplon is combined with Benperidol.Approved, Investigational
Benzyl alcoholThe risk or severity of adverse effects can be increased when Benzyl alcohol is combined with Indiplon.Approved
BrexpiprazoleThe risk or severity of adverse effects can be increased when Brexpiprazole is combined with Indiplon.Approved, Investigational
BrimonidineBrimonidine may increase the central nervous system depressant (CNS depressant) activities of Indiplon.Approved
BromazepamThe risk or severity of adverse effects can be increased when Bromazepam is combined with Indiplon.Approved, Illicit, Investigational
BromisovalThe risk or severity of adverse effects can be increased when Indiplon is combined with Bromisoval.Experimental
BromperidolThe risk or severity of adverse effects can be increased when Bromperidol is combined with Indiplon.Approved, Investigational
BrompheniramineThe risk or severity of adverse effects can be increased when Brompheniramine is combined with Indiplon.Approved
BrotizolamThe risk or severity of adverse effects can be increased when Brotizolam is combined with Indiplon.Approved, Investigational, Withdrawn
BupivacaineThe risk or severity of adverse effects can be increased when Bupivacaine is combined with Indiplon.Approved, Investigational
BuprenorphineIndiplon may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.Approved, Illicit, Investigational, Vet Approved
BupropionThe risk or severity of adverse effects can be increased when Indiplon is combined with Bupropion.Approved
BuspironeThe risk or severity of adverse effects can be increased when Buspirone is combined with Indiplon.Approved, Investigational
ButabarbitalThe risk or severity of adverse effects can be increased when Butabarbital is combined with Indiplon.Approved, Illicit
ButacaineThe risk or severity of adverse effects can be increased when Butacaine is combined with Indiplon.Vet Approved
ButalbitalThe risk or severity of adverse effects can be increased when Butalbital is combined with Indiplon.Approved, Illicit
ButambenThe risk or severity of adverse effects can be increased when Butamben is combined with Indiplon.Approved, Withdrawn
ButethalThe risk or severity of adverse effects can be increased when Butethal is combined with Indiplon.Approved, Illicit
ButorphanolThe risk or severity of adverse effects can be increased when Butorphanol is combined with Indiplon.Approved, Illicit, Vet Approved
CanertinibThe risk or severity of adverse effects can be increased when Canertinib is combined with Indiplon.Investigational
CarbamazepineThe risk or severity of adverse effects can be increased when Carbamazepine is combined with Indiplon.Approved, Investigational
CarbinoxamineThe risk or severity of adverse effects can be increased when Carbinoxamine is combined with Indiplon.Approved
CarfentanilThe risk or severity of adverse effects can be increased when Carfentanil is combined with Indiplon.Illicit, Investigational, Vet Approved
CarisoprodolThe risk or severity of adverse effects can be increased when Carisoprodol is combined with Indiplon.Approved
CetirizineThe risk or severity of adverse effects can be increased when Cetirizine is combined with Indiplon.Approved
Chloral hydrateThe risk or severity of adverse effects can be increased when Chloral hydrate is combined with Indiplon.Approved, Illicit, Investigational, Vet Approved
ChlordiazepoxideThe risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Indiplon.Approved, Illicit, Investigational
ChloroprocaineThe risk or severity of adverse effects can be increased when Chloroprocaine is combined with Indiplon.Approved
ChlorphenamineThe risk or severity of adverse effects can be increased when Chlorphenamine is combined with Indiplon.Approved
ChlorpromazineThe risk or severity of adverse effects can be increased when Chlorpromazine is combined with Indiplon.Approved, Investigational, Vet Approved
ChlorprothixeneThe risk or severity of adverse effects can be increased when Chlorprothixene is combined with Indiplon.Approved, Investigational, Withdrawn
ChlorzoxazoneThe risk or severity of adverse effects can be increased when Chlorzoxazone is combined with Indiplon.Approved
CinchocaineThe risk or severity of adverse effects can be increased when Cinchocaine is combined with Indiplon.Approved, Vet Approved
CitalopramThe risk or severity of adverse effects can be increased when Indiplon is combined with Citalopram.Approved
ClemastineThe risk or severity of adverse effects can be increased when Clemastine is combined with Indiplon.Approved, Investigational
ClidiniumThe risk or severity of adverse effects can be increased when Clidinium is combined with Indiplon.Approved
ClobazamThe risk or severity of adverse effects can be increased when Clobazam is combined with Indiplon.Approved, Illicit
clomethiazoleThe risk or severity of adverse effects can be increased when clomethiazole is combined with Indiplon.Investigational
ClomipramineThe risk or severity of adverse effects can be increased when Clomipramine is combined with Indiplon.Approved, Investigational, Vet Approved
ClonazepamThe risk or severity of adverse effects can be increased when Clonazepam is combined with Indiplon.Approved, Illicit
ClonidineThe risk or severity of adverse effects can be increased when Clonidine is combined with Indiplon.Approved
ClopenthixolThe risk or severity of adverse effects can be increased when Indiplon is combined with Clopenthixol.Experimental
ClorazepateThe risk or severity of adverse effects can be increased when Clorazepate is combined with Indiplon.Approved, Illicit
ClothiapineThe risk or severity of adverse effects can be increased when Indiplon is combined with Clothiapine.Experimental
ClozapineThe risk or severity of adverse effects can be increased when Clozapine is combined with Indiplon.Approved
CocaineThe risk or severity of adverse effects can be increased when Cocaine is combined with Indiplon.Approved, Illicit
CodeineThe risk or severity of adverse effects can be increased when Codeine is combined with Indiplon.Approved, Illicit
CyclizineThe risk or severity of adverse effects can be increased when Cyclizine is combined with Indiplon.Approved
CyclobenzaprineThe risk or severity of adverse effects can be increased when Cyclobenzaprine is combined with Indiplon.Approved
CyclopropaneThe risk or severity of adverse effects can be increased when Indiplon is combined with Cyclopropane.Experimental
CyclosporineThe risk or severity of adverse effects can be increased when Indiplon is combined with Cyclosporine.Approved, Investigational, Vet Approved
CyproheptadineThe risk or severity of adverse effects can be increased when Cyproheptadine is combined with Indiplon.Approved
DantroleneThe risk or severity of adverse effects can be increased when Dantrolene is combined with Indiplon.Approved, Investigational
DapiprazoleThe risk or severity of adverse effects can be increased when Dapiprazole is combined with Indiplon.Approved
DapoxetineThe risk or severity of adverse effects can be increased when Indiplon is combined with Dapoxetine.Investigational
DeramciclaneThe risk or severity of adverse effects can be increased when Deramciclane is combined with Indiplon.Investigational
DesfluraneThe risk or severity of adverse effects can be increased when Desflurane is combined with Indiplon.Approved
DesipramineThe risk or severity of adverse effects can be increased when Desipramine is combined with Indiplon.Approved, Investigational
DesloratadineThe risk or severity of adverse effects can be increased when Desloratadine is combined with Indiplon.Approved, Investigational
DesvenlafaxineThe risk or severity of adverse effects can be increased when Indiplon is combined with Desvenlafaxine.Approved, Investigational
DetomidineThe risk or severity of adverse effects can be increased when Detomidine is combined with Indiplon.Vet Approved
DeutetrabenazineThe risk or severity of sedation and somnolence can be increased when Indiplon is combined with Deutetrabenazine.Approved, Investigational
DexbrompheniramineThe risk or severity of adverse effects can be increased when Dexbrompheniramine is combined with Indiplon.Approved
DexmedetomidineThe risk or severity of adverse effects can be increased when Dexmedetomidine is combined with Indiplon.Approved, Vet Approved
DextromoramideThe risk or severity of adverse effects can be increased when Dextromoramide is combined with Indiplon.Experimental, Illicit
DextropropoxypheneThe risk or severity of adverse effects can be increased when Dextropropoxyphene is combined with Indiplon.Approved, Illicit, Investigational, Withdrawn
DezocineThe risk or severity of adverse effects can be increased when Dezocine is combined with Indiplon.Approved, Investigational
DiazepamThe risk or severity of adverse effects can be increased when Diazepam is combined with Indiplon.Approved, Illicit, Investigational, Vet Approved
Diethyl etherThe risk or severity of adverse effects can be increased when Indiplon is combined with Diethyl ether.Experimental
DifenoxinThe risk or severity of adverse effects can be increased when Difenoxin is combined with Indiplon.Approved, Illicit
DihydrocodeineThe risk or severity of adverse effects can be increased when Dihydrocodeine is combined with Indiplon.Approved, Illicit
DihydroetorphineThe risk or severity of adverse effects can be increased when Dihydroetorphine is combined with Indiplon.Experimental, Illicit
DihydromorphineThe risk or severity of adverse effects can be increased when Dihydromorphine is combined with Indiplon.Experimental, Illicit
DimenhydrinateThe risk or severity of adverse effects can be increased when Dimenhydrinate is combined with Indiplon.Approved
DiphenhydramineThe risk or severity of adverse effects can be increased when Diphenhydramine is combined with Indiplon.Approved, Investigational
DiphenoxylateThe risk or severity of adverse effects can be increased when Diphenoxylate is combined with Indiplon.Approved, Illicit
DixyrazineThe risk or severity of adverse effects can be increased when Indiplon is combined with Dixyrazine.Experimental
DoramectinThe risk or severity of adverse effects can be increased when Doramectin is combined with Indiplon.Vet Approved
DoxepinThe risk or severity of adverse effects can be increased when Doxepin is combined with Indiplon.Approved, Investigational
DoxylamineDoxylamine may increase the central nervous system depressant (CNS depressant) activities of Indiplon.Approved, Vet Approved
DPDPEThe risk or severity of adverse effects can be increased when DPDPE is combined with Indiplon.Experimental
DronabinolDronabinol may increase the central nervous system depressant (CNS depressant) activities of Indiplon.Approved, Illicit
DroperidolDroperidol may increase the central nervous system depressant (CNS depressant) activities of Indiplon.Approved, Vet Approved
DrotebanolThe risk or severity of adverse effects can be increased when Drotebanol is combined with Indiplon.Experimental, Illicit
DuloxetineThe risk or severity of adverse effects can be increased when Indiplon is combined with Duloxetine.Approved
DyclonineThe risk or severity of adverse effects can be increased when Dyclonine is combined with Indiplon.Approved
EcgonineThe risk or severity of adverse effects can be increased when Ecgonine is combined with Indiplon.Experimental, Illicit
EcopipamThe risk or severity of adverse effects can be increased when Ecopipam is combined with Indiplon.Investigational
EfavirenzThe risk or severity of adverse effects can be increased when Efavirenz is combined with Indiplon.Approved, Investigational
EltanoloneThe risk or severity of adverse effects can be increased when Eltanolone is combined with Indiplon.Investigational
EnfluraneThe risk or severity of adverse effects can be increased when Enflurane is combined with Indiplon.Approved, Investigational, Vet Approved
EntacaponeThe risk or severity of adverse effects can be increased when Entacapone is combined with Indiplon.Approved, Investigational
EscitalopramThe risk or severity of adverse effects can be increased when Indiplon is combined with Escitalopram.Approved, Investigational
EstazolamThe risk or severity of adverse effects can be increased when Estazolam is combined with Indiplon.Approved, Illicit
EszopicloneThe risk or severity of adverse effects can be increased when Eszopiclone is combined with Indiplon.Approved, Investigational
EthanolIndiplon may increase the central nervous system depressant (CNS depressant) activities of Ethanol.Approved
EthchlorvynolThe risk or severity of adverse effects can be increased when Ethchlorvynol is combined with Indiplon.Approved, Illicit, Withdrawn
EthosuximideThe risk or severity of adverse effects can be increased when Ethosuximide is combined with Indiplon.Approved
EthotoinThe risk or severity of adverse effects can be increased when Ethotoin is combined with Indiplon.Approved
Ethyl carbamateThe risk or severity of adverse effects can be increased when Ethyl carbamate is combined with Indiplon.Withdrawn
Ethyl chlorideThe risk or severity of adverse effects can be increased when Indiplon is combined with Ethyl chloride.Approved, Experimental, Investigational
Ethyl loflazepateThe risk or severity of adverse effects can be increased when Ethyl loflazepate is combined with Indiplon.Approved, Illicit
EthylmorphineThe risk or severity of adverse effects can be increased when Ethylmorphine is combined with Indiplon.Approved, Illicit
EtidocaineThe risk or severity of adverse effects can be increased when Etidocaine is combined with Indiplon.Approved
EtifoxineThe risk or severity of adverse effects can be increased when Etifoxine is combined with Indiplon.Investigational, Withdrawn
EtizolamThe risk or severity of adverse effects can be increased when Etizolam is combined with Indiplon.Approved
EtomidateThe risk or severity of adverse effects can be increased when Etomidate is combined with Indiplon.Approved
EtoperidoneThe risk or severity of adverse effects can be increased when Indiplon is combined with Etoperidone.Withdrawn
EtorphineThe risk or severity of adverse effects can be increased when Etorphine is combined with Indiplon.Illicit, Vet Approved
EzogabineThe risk or severity of adverse effects can be increased when Ezogabine is combined with Indiplon.Approved, Investigational
FelbamateThe risk or severity of adverse effects can be increased when Felbamate is combined with Indiplon.Approved
FencamfamineThe risk or severity of adverse effects can be increased when Fencamfamine is combined with Indiplon.Approved, Illicit, Withdrawn
FentanylThe risk or severity of adverse effects can be increased when Fentanyl is combined with Indiplon.Approved, Illicit, Investigational, Vet Approved
FexofenadineThe risk or severity of adverse effects can be increased when Fexofenadine is combined with Indiplon.Approved, Investigational
FlibanserinThe risk or severity of adverse effects can be increased when Flibanserin is combined with Indiplon.Approved, Investigational
FluanisoneThe risk or severity of adverse effects can be increased when Indiplon is combined with Fluanisone.Experimental
FludiazepamThe risk or severity of adverse effects can be increased when Fludiazepam is combined with Indiplon.Approved, Illicit
FlunarizineThe risk or severity of adverse effects can be increased when Flunarizine is combined with Indiplon.Approved
FlunitrazepamThe risk or severity of adverse effects can be increased when Flunitrazepam is combined with Indiplon.Approved, Illicit
FluoxetineThe risk or severity of adverse effects can be increased when Indiplon is combined with Fluoxetine.Approved, Vet Approved
FlupentixolThe risk or severity of adverse effects can be increased when Flupentixol is combined with Indiplon.Approved, Investigational, Withdrawn
FluphenazineThe risk or severity of adverse effects can be increased when Fluphenazine is combined with Indiplon.Approved
FlurazepamThe risk or severity of adverse effects can be increased when Flurazepam is combined with Indiplon.Approved, Illicit, Investigational
FluspirileneThe risk or severity of adverse effects can be increased when Fluspirilene is combined with Indiplon.Approved, Investigational
Fluticasone propionateThe risk or severity of adverse effects can be increased when Fluticasone propionate is combined with Indiplon.Approved
FluvoxamineThe risk or severity of adverse effects can be increased when Fluvoxamine is combined with Indiplon.Approved, Investigational
FospropofolThe risk or severity of adverse effects can be increased when Fospropofol is combined with Indiplon.Approved, Illicit, Investigational
GabapentinThe risk or severity of adverse effects can be increased when Gabapentin is combined with Indiplon.Approved, Investigational
Gabapentin EnacarbilThe risk or severity of adverse effects can be increased when Gabapentin Enacarbil is combined with Indiplon.Approved, Investigational
Gamma Hydroxybutyric AcidThe risk or severity of adverse effects can be increased when Gamma Hydroxybutyric Acid is combined with Indiplon.Approved, Illicit, Investigational
GepironeThe risk or severity of adverse effects can be increased when Gepirone is combined with Indiplon.Investigational
GlutethimideThe risk or severity of adverse effects can be increased when Glutethimide is combined with Indiplon.Approved, Illicit
GuanfacineThe risk or severity of adverse effects can be increased when Guanfacine is combined with Indiplon.Approved, Investigational
HalazepamThe risk or severity of adverse effects can be increased when Halazepam is combined with Indiplon.Approved, Illicit, Withdrawn
HaloperidolThe risk or severity of adverse effects can be increased when Haloperidol is combined with Indiplon.Approved
HalothaneThe risk or severity of adverse effects can be increased when Halothane is combined with Indiplon.Approved, Vet Approved
HeroinThe risk or severity of adverse effects can be increased when Heroin is combined with Indiplon.Approved, Illicit, Investigational
HexobarbitalThe risk or severity of adverse effects can be increased when Hexobarbital is combined with Indiplon.Approved
HydrocodoneIndiplon may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.Approved, Illicit
HydromorphoneThe risk or severity of adverse effects can be increased when Hydromorphone is combined with Indiplon.Approved, Illicit
IloperidoneThe risk or severity of adverse effects can be increased when Iloperidone is combined with Indiplon.Approved
ImipramineThe risk or severity of adverse effects can be increased when Imipramine is combined with Indiplon.Approved
IndalpineThe risk or severity of adverse effects can be increased when Indiplon is combined with Indalpine.Investigational, Withdrawn
IsofluraneThe risk or severity of adverse effects can be increased when Isoflurane is combined with Indiplon.Approved, Vet Approved
KetamineThe risk or severity of adverse effects can be increased when Ketamine is combined with Indiplon.Approved, Vet Approved
KetazolamThe risk or severity of adverse effects can be increased when Ketazolam is combined with Indiplon.Approved
KetobemidoneThe risk or severity of adverse effects can be increased when Ketobemidone is combined with Indiplon.Approved, Investigational
LamotrigineThe risk or severity of adverse effects can be increased when Lamotrigine is combined with Indiplon.Approved, Investigational
LevetiracetamThe risk or severity of adverse effects can be increased when Levetiracetam is combined with Indiplon.Approved, Investigational
LevobupivacaineThe risk or severity of adverse effects can be increased when Levobupivacaine is combined with Indiplon.Approved, Investigational
LevocabastineThe risk or severity of adverse effects can be increased when Indiplon is combined with Levocabastine.Approved, Investigational
LevocetirizineThe risk or severity of adverse effects can be increased when Levocetirizine is combined with Indiplon.Approved
LevodopaThe risk or severity of adverse effects can be increased when Levodopa is combined with Indiplon.Approved
Levomethadyl AcetateThe risk or severity of adverse effects can be increased when Levomethadyl Acetate is combined with Indiplon.Approved, Investigational
LevomilnacipranThe risk or severity of adverse effects can be increased when Indiplon is combined with Levomilnacipran.Approved, Investigational
LevorphanolThe risk or severity of adverse effects can be increased when Levorphanol is combined with Indiplon.Approved
LidocaineThe risk or severity of adverse effects can be increased when Lidocaine is combined with Indiplon.Approved, Vet Approved
Lithium cationThe risk or severity of adverse effects can be increased when Lithium is combined with Indiplon.Experimental
LofentanilThe risk or severity of adverse effects can be increased when Lofentanil is combined with Indiplon.Illicit
LofexidineThe therapeutic efficacy of Indiplon can be increased when used in combination with Lofexidine.Approved, Investigational
LoprazolamThe risk or severity of adverse effects can be increased when Indiplon is combined with Loprazolam.Experimental
LoratadineThe risk or severity of adverse effects can be increased when Loratadine is combined with Indiplon.Approved, Investigational
LorazepamThe risk or severity of adverse effects can be increased when Lorazepam is combined with Indiplon.Approved
LormetazepamThe risk or severity of adverse effects can be increased when Indiplon is combined with Lormetazepam.Approved
LoxapineThe risk or severity of adverse effects can be increased when Loxapine is combined with Indiplon.Approved
LurasidoneThe risk or severity of adverse effects can be increased when Lurasidone is combined with Indiplon.Approved, Investigational
Magnesium carbonateThe risk or severity of adverse effects can be increased when Indiplon is combined with Magnesium carbonate.Approved, Investigational
Magnesium hydroxideThe risk or severity of adverse effects can be increased when Indiplon is combined with Magnesium hydroxide.Approved, Investigational
Magnesium sulfateThe therapeutic efficacy of Indiplon can be increased when used in combination with Magnesium sulfate.Approved, Investigational, Vet Approved
Magnesium TrisilicateThe risk or severity of adverse effects can be increased when Indiplon is combined with Magnesium Trisilicate.Approved
MaprotilineThe risk or severity of adverse effects can be increased when Maprotiline is combined with Indiplon.Approved, Investigational
MebicarThe risk or severity of adverse effects can be increased when Indiplon is combined with Mebicar.Experimental
MeclizineThe risk or severity of adverse effects can be increased when Meclizine is combined with Indiplon.Approved
MedazepamThe risk or severity of adverse effects can be increased when Indiplon is combined with Medazepam.Experimental
MedetomidineThe risk or severity of adverse effects can be increased when Medetomidine is combined with Indiplon.Vet Approved
MelatoninThe risk or severity of adverse effects can be increased when Melatonin is combined with Indiplon.Approved, Nutraceutical, Vet Approved
MelperoneThe risk or severity of adverse effects can be increased when Melperone is combined with Indiplon.Approved, Investigational
MepivacaineThe risk or severity of adverse effects can be increased when Mepivacaine is combined with Indiplon.Approved, Vet Approved
MeprobamateThe risk or severity of adverse effects can be increased when Meprobamate is combined with Indiplon.Approved, Illicit
MeptazinolThe risk or severity of adverse effects can be increased when Indiplon is combined with Meptazinol.Experimental
MesoridazineThe risk or severity of adverse effects can be increased when Mesoridazine is combined with Indiplon.Approved, Investigational
MetaxaloneThe risk or severity of adverse effects can be increased when Metaxalone is combined with Indiplon.Approved
MethadoneThe risk or severity of adverse effects can be increased when Methadone is combined with Indiplon.Approved
Methadyl AcetateThe risk or severity of adverse effects can be increased when Methadyl Acetate is combined with Indiplon.Approved, Illicit
MethapyrileneThe risk or severity of adverse effects can be increased when Methapyrilene is combined with Indiplon.Withdrawn
MethaqualoneThe risk or severity of adverse effects can be increased when Methaqualone is combined with Indiplon.Illicit, Withdrawn
MethocarbamolThe risk or severity of adverse effects can be increased when Methocarbamol is combined with Indiplon.Approved, Vet Approved
MethohexitalThe risk or severity of adverse effects can be increased when Methohexital is combined with Indiplon.Approved
MethotrimeprazineIndiplon may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.Approved, Investigational
MethoxyfluraneThe risk or severity of adverse effects can be increased when Methoxyflurane is combined with Indiplon.Approved, Investigational, Vet Approved
MethsuximideThe risk or severity of adverse effects can be increased when Methsuximide is combined with Indiplon.Approved
MethylecgonineThe risk or severity of adverse effects can be increased when Methylecgonine is combined with Indiplon.Experimental
MethylphenobarbitalThe risk or severity of adverse effects can be increased when Methylphenobarbital is combined with Indiplon.Approved
MetyrosineIndiplon may increase the sedative activities of Metyrosine.Approved
MidazolamThe risk or severity of adverse effects can be increased when Midazolam is combined with Indiplon.Approved, Illicit
MilnacipranThe risk or severity of adverse effects can be increased when Indiplon is combined with Milnacipran.Approved, Investigational
MinocyclineMinocycline may increase the central nervous system depressant (CNS depressant) activities of Indiplon.Approved, Investigational
MirtazapineIndiplon may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.Approved
MolindoneThe risk or severity of adverse effects can be increased when Molindone is combined with Indiplon.Approved
MorphineThe risk or severity of adverse effects can be increased when Morphine is combined with Indiplon.Approved, Investigational
NabiloneNabilone may increase the central nervous system depressant (CNS depressant) activities of Indiplon.Approved, Investigational
NalbuphineThe risk or severity of adverse effects can be increased when Nalbuphine is combined with Indiplon.Approved
NefazodoneThe risk or severity of adverse effects can be increased when Indiplon is combined with Nefazodone.Approved, Withdrawn
NeomycinThe risk or severity of adverse effects can be increased when Indiplon is combined with Neomycin.Approved, Vet Approved
NitrazepamThe risk or severity of adverse effects can be increased when Nitrazepam is combined with Indiplon.Approved
Nitrous oxideThe risk or severity of adverse effects can be increased when Nitrous oxide is combined with Indiplon.Approved, Vet Approved
NordazepamThe risk or severity of adverse effects can be increased when Indiplon is combined with Nordazepam.Approved
NorfluraneThe risk or severity of adverse effects can be increased when Indiplon is combined with Norflurane.Approved, Investigational
NormethadoneThe risk or severity of adverse effects can be increased when Normethadone is combined with Indiplon.Approved, Illicit
NortriptylineThe risk or severity of adverse effects can be increased when Nortriptyline is combined with Indiplon.Approved
OlanzapineThe risk or severity of adverse effects can be increased when Olanzapine is combined with Indiplon.Approved, Investigational
OlopatadineThe risk or severity of adverse effects can be increased when Olopatadine is combined with Indiplon.Approved
OndansetronThe risk or severity of adverse effects can be increased when Ondansetron is combined with Indiplon.Approved
OpiumThe risk or severity of adverse effects can be increased when Opium is combined with Indiplon.Approved, Illicit
OrphenadrineIndiplon may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.Approved
OsanetantThe risk or severity of adverse effects can be increased when Osanetant is combined with Indiplon.Investigational
OxazepamThe risk or severity of adverse effects can be increased when Oxazepam is combined with Indiplon.Approved
OxprenololThe risk or severity of adverse effects can be increased when Oxprenolol is combined with Indiplon.Approved
OxybuprocaineThe risk or severity of adverse effects can be increased when Oxybuprocaine is combined with Indiplon.Approved, Investigational
OxycodoneThe risk or severity of adverse effects can be increased when Oxycodone is combined with Indiplon.Approved, Illicit, Investigational
OxymorphoneThe risk or severity of adverse effects can be increased when Oxymorphone is combined with Indiplon.Approved, Investigational, Vet Approved
PaliperidoneThe risk or severity of adverse effects can be increased when Paliperidone is combined with Indiplon.Approved
ParaldehydeIndiplon may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.Approved, Investigational
ParoxetineThe risk or severity of adverse effects can be increased when Indiplon is combined with Paroxetine.Approved, Investigational
PenfluridolThe risk or severity of adverse effects can be increased when Indiplon is combined with Penfluridol.Experimental
PentazocineThe risk or severity of adverse effects can be increased when Pentazocine is combined with Indiplon.Approved, Vet Approved
PentobarbitalThe risk or severity of adverse effects can be increased when Pentobarbital is combined with Indiplon.Approved, Investigational, Vet Approved
PerampanelPerampanel may increase the central nervous system depressant (CNS depressant) activities of Indiplon.Approved
PerazineThe risk or severity of adverse effects can be increased when Indiplon is combined with Perazine.Approved, Investigational
PerospironeThe risk or severity of adverse effects can be increased when Perospirone is combined with Indiplon.Approved
PerphenazineThe risk or severity of adverse effects can be increased when Perphenazine is combined with Indiplon.Approved
PethidineThe risk or severity of adverse effects can be increased when Pethidine is combined with Indiplon.Approved
PhenazocineThe risk or severity of adverse effects can be increased when Indiplon is combined with Phenazocine.Experimental
PhenibutThe risk or severity of adverse effects can be increased when Indiplon is combined with Phenibut.Experimental
PhenobarbitalThe risk or severity of adverse effects can be increased when Phenobarbital is combined with Indiplon.Approved, Investigational
PhenoperidineThe risk or severity of adverse effects can be increased when Indiplon is combined with Phenoperidine.Experimental
PhenoxyethanolThe risk or severity of adverse effects can be increased when Phenoxyethanol is combined with Indiplon.Approved
PhenytoinThe risk or severity of adverse effects can be increased when Phenytoin is combined with Indiplon.Approved, Vet Approved
PimozideThe risk or severity of adverse effects can be increased when Pimozide is combined with Indiplon.Approved
PipamperoneThe risk or severity of adverse effects can be increased when Pipamperone is combined with Indiplon.Approved, Investigational
PipotiazineThe risk or severity of adverse effects can be increased when Pipotiazine is combined with Indiplon.Approved, Investigational
PiritramideThe risk or severity of adverse effects can be increased when Piritramide is combined with Indiplon.Approved, Investigational
PizotifenThe risk or severity of adverse effects can be increased when Pizotifen is combined with Indiplon.Approved
Polymyxin B SulfateThe risk or severity of adverse effects can be increased when Indiplon is combined with Polymyxin B Sulfate.Approved, Vet Approved
PomalidomideThe risk or severity of adverse effects can be increased when Pomalidomide is combined with Indiplon.Approved
PramipexoleIndiplon may increase the sedative activities of Pramipexole.Approved, Investigational
PrazepamThe risk or severity of adverse effects can be increased when Prazepam is combined with Indiplon.Approved, Illicit
PregabalinThe therapeutic efficacy of Indiplon can be increased when used in combination with Pregabalin.Approved, Illicit, Investigational
PrilocaineThe risk or severity of adverse effects can be increased when Prilocaine is combined with Indiplon.Approved
PrimidoneThe risk or severity of adverse effects can be increased when Primidone is combined with Indiplon.Approved, Vet Approved
ProcaineThe risk or severity of adverse effects can be increased when Procaine is combined with Indiplon.Approved, Investigational, Vet Approved
ProchlorperazineThe risk or severity of adverse effects can be increased when Prochlorperazine is combined with Indiplon.Approved, Vet Approved
PromazineThe risk or severity of adverse effects can be increased when Promazine is combined with Indiplon.Approved, Vet Approved
PromethazineThe risk or severity of adverse effects can be increased when Promethazine is combined with Indiplon.Approved, Investigational
PropanididThe risk or severity of adverse effects can be increased when Indiplon is combined with Propanidid.Experimental
ProparacaineThe risk or severity of adverse effects can be increased when Proparacaine is combined with Indiplon.Approved, Vet Approved
PropofolThe risk or severity of adverse effects can be increased when Propofol is combined with Indiplon.Approved, Investigational, Vet Approved
PropoxycaineThe risk or severity of adverse effects can be increased when Propoxycaine is combined with Indiplon.Approved
ProtriptylineThe risk or severity of adverse effects can be increased when Protriptyline is combined with Indiplon.Approved
ProxibarbalThe risk or severity of adverse effects can be increased when Indiplon is combined with Proxibarbal.Experimental
PSD502The risk or severity of adverse effects can be increased when PSD502 is combined with Indiplon.Investigational
PseudoephedrineThe risk or severity of adverse effects can be increased when Indiplon is combined with Pseudoephedrine.Approved
QuazepamThe risk or severity of adverse effects can be increased when Quazepam is combined with Indiplon.Approved, Illicit
QuetiapineThe risk or severity of adverse effects can be increased when Quetiapine is combined with Indiplon.Approved
QuinisocaineThe risk or severity of adverse effects can be increased when Indiplon is combined with Quinisocaine.Experimental
RacloprideThe risk or severity of adverse effects can be increased when Raclopride is combined with Indiplon.Investigational
RamelteonThe risk or severity of adverse effects can be increased when Ramelteon is combined with Indiplon.Approved, Investigational
RemifentanilThe risk or severity of adverse effects can be increased when Remifentanil is combined with Indiplon.Approved
RemoxiprideThe risk or severity of adverse effects can be increased when Remoxipride is combined with Indiplon.Approved, Withdrawn
ReserpineThe risk or severity of adverse effects can be increased when Reserpine is combined with Indiplon.Approved, Investigational
RisperidoneThe risk or severity of adverse effects can be increased when Risperidone is combined with Indiplon.Approved, Investigational
RitanserinThe risk or severity of adverse effects can be increased when Indiplon is combined with Ritanserin.Investigational
RomifidineThe risk or severity of adverse effects can be increased when Romifidine is combined with Indiplon.Vet Approved
RopiniroleIndiplon may increase the sedative activities of Ropinirole.Approved, Investigational
RopivacaineThe risk or severity of adverse effects can be increased when Ropivacaine is combined with Indiplon.Approved
RotigotineIndiplon may increase the sedative activities of Rotigotine.Approved
RufinamideThe risk or severity of adverse effects can be increased when Rufinamide is combined with Indiplon.Approved
ScopolamineThe risk or severity of adverse effects can be increased when Scopolamine is combined with Indiplon.Approved, Investigational
SecobarbitalThe risk or severity of adverse effects can be increased when Secobarbital is combined with Indiplon.Approved, Vet Approved
SepranoloneThe risk or severity of adverse effects can be increased when Indiplon is combined with Sepranolone.Investigational
SertindoleThe risk or severity of adverse effects can be increased when Sertindole is combined with Indiplon.Approved, Investigational, Withdrawn
SertralineThe risk or severity of adverse effects can be increased when Indiplon is combined with Sertraline.Approved
SevofluraneThe risk or severity of adverse effects can be increased when Sevoflurane is combined with Indiplon.Approved, Vet Approved
Sodium oxybateSodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Indiplon.Approved
StiripentolThe risk or severity of adverse effects can be increased when Stiripentol is combined with Indiplon.Approved
SufentanilThe risk or severity of adverse effects can be increased when Sufentanil is combined with Indiplon.Approved, Investigational
SulpirideThe risk or severity of adverse effects can be increased when Sulpiride is combined with Indiplon.Approved, Investigational
SultoprideThe risk or severity of adverse effects can be increased when Indiplon is combined with Sultopride.Experimental
SuvorexantIndiplon may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.Approved, Investigational
TandospironeThe risk or severity of adverse effects can be increased when Indiplon is combined with Tandospirone.Investigational
TapentadolTapentadol may increase the central nervous system depressant (CNS depressant) activities of Indiplon.Approved
TasimelteonThe risk or severity of adverse effects can be increased when Tasimelteon is combined with Indiplon.Approved, Investigational
TemazepamThe risk or severity of adverse effects can be increased when Temazepam is combined with Indiplon.Approved, Investigational
TetrabenazineThe risk or severity of adverse effects can be increased when Tetrabenazine is combined with Indiplon.Approved, Investigational
TetracaineThe risk or severity of adverse effects can be increased when Tetracaine is combined with Indiplon.Approved, Vet Approved
TetrahydropalmatineThe risk or severity of adverse effects can be increased when Tetrahydropalmatine is combined with Indiplon.Investigational
TetrodotoxinThe risk or severity of adverse effects can be increased when Tetrodotoxin is combined with Indiplon.Investigational
ThalidomideIndiplon may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.Approved, Investigational, Withdrawn
ThiamylalThe risk or severity of adverse effects can be increased when Thiamylal is combined with Indiplon.Approved, Vet Approved
ThiopentalThe risk or severity of adverse effects can be increased when Thiopental is combined with Indiplon.Approved, Vet Approved
ThioridazineThe risk or severity of adverse effects can be increased when Thioridazine is combined with Indiplon.Approved, Withdrawn
ThiothixeneThe risk or severity of adverse effects can be increased when Thiothixene is combined with Indiplon.Approved
TiagabineThe risk or severity of adverse effects can be increased when Tiagabine is combined with Indiplon.Approved, Investigational
TiaprideThe risk or severity of adverse effects can be increased when Indiplon is combined with Tiapride.Approved, Investigational
TiletamineThe risk or severity of adverse effects can be increased when Tiletamine is combined with Indiplon.Vet Approved
TilidineThe risk or severity of adverse effects can be increased when Indiplon is combined with Tilidine.Experimental
TizanidineThe risk or severity of adverse effects can be increased when Tizanidine is combined with Indiplon.Approved, Investigational
TolcaponeThe risk or severity of adverse effects can be increased when Tolcapone is combined with Indiplon.Approved, Withdrawn
TopiramateThe risk or severity of adverse effects can be increased when Topiramate is combined with Indiplon.Approved
TramadolThe risk or severity of adverse effects can be increased when Tramadol is combined with Indiplon.Approved, Investigational
TranylcypromineThe risk or severity of adverse effects can be increased when Tranylcypromine is combined with Indiplon.Approved, Investigational
TrazodoneThe risk or severity of adverse effects can be increased when Trazodone is combined with Indiplon.Approved, Investigational
TriazolamThe risk or severity of adverse effects can be increased when Triazolam is combined with Indiplon.Approved, Investigational
Tricaine methanesulfonateThe risk or severity of adverse effects can be increased when Tricaine methanesulfonate is combined with Indiplon.Vet Approved
TrichloroethyleneThe risk or severity of adverse effects can be increased when Indiplon is combined with Trichloroethylene.Approved
TrifluoperazineThe risk or severity of adverse effects can be increased when Trifluoperazine is combined with Indiplon.Approved, Investigational
TrifluperidolThe risk or severity of adverse effects can be increased when Indiplon is combined with Trifluperidol.Experimental
TriflupromazineThe risk or severity of adverse effects can be increased when Triflupromazine is combined with Indiplon.Approved, Vet Approved
TrimipramineThe risk or severity of adverse effects can be increased when Trimipramine is combined with Indiplon.Approved
TriprolidineThe risk or severity of adverse effects can be increased when Triprolidine is combined with Indiplon.Approved
Valproic AcidThe risk or severity of adverse effects can be increased when Valproic Acid is combined with Indiplon.Approved, Investigational
VenlafaxineThe risk or severity of adverse effects can be increased when Indiplon is combined with Venlafaxine.Approved
VeraliprideThe risk or severity of adverse effects can be increased when Indiplon is combined with Veralipride.Experimental
VigabatrinThe risk or severity of adverse effects can be increased when Vigabatrin is combined with Indiplon.Approved
Vinyl etherThe risk or severity of adverse effects can be increased when Indiplon is combined with Vinyl ether.Experimental
VortioxetineThe risk or severity of adverse effects can be increased when Vortioxetine is combined with Indiplon.Approved, Investigational
XenonThe risk or severity of adverse effects can be increased when Indiplon is combined with Xenon.Experimental
XylazineThe risk or severity of adverse effects can be increased when Xylazine is combined with Indiplon.Vet Approved
ZaleplonThe risk or severity of adverse effects can be increased when Zaleplon is combined with Indiplon.Approved, Illicit, Investigational
ZiconotideThe risk or severity of adverse effects can be increased when Ziconotide is combined with Indiplon.Approved
ZimelidineThe risk or severity of adverse effects can be increased when Indiplon is combined with Zimelidine.Withdrawn
ZiprasidoneThe risk or severity of adverse effects can be increased when Ziprasidone is combined with Indiplon.Approved
ZolazepamThe risk or severity of adverse effects can be increased when Zolazepam is combined with Indiplon.Vet Approved
ZolpidemIndiplon may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.Approved
ZonisamideThe risk or severity of adverse effects can be increased when Zonisamide is combined with Indiplon.Approved, Investigational
ZopicloneThe risk or severity of adverse effects can be increased when Zopiclone is combined with Indiplon.Approved
ZotepineThe risk or severity of adverse effects can be increased when Zotepine is combined with Indiplon.Approved, Investigational, Withdrawn
ZuclopenthixolThe risk or severity of adverse effects can be increased when Zuclopenthixol is combined with Indiplon.Approved, Investigational
Food Interactions
Not Available

References

General References
Not Available
External Links
PubChem Compound
6450813
PubChem Substance
347828809
ChemSpider
4953363
BindingDB
86522
ChEMBL
CHEMBL262075
Wikipedia
Indiplon

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3TerminatedTreatmentDepression / Sleeplessness1
3WithdrawnTreatmentSleeplessness1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.00449 mg/mLALOGPS
logP3.01ALOGPS
logP2.69ChemAxon
logS-4.9ALOGPS
pKa (Strongest Basic)0.96ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area67.57 Å2ChemAxon
Rotatable Bond Count4ChemAxon
Refractivity114.23 m3·mol-1ChemAxon
Polarizability39.66 Å3ChemAxon
Number of Rings4ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as phenylpyrimidines. These are polycyclic aromatic compounds containing a benzene ring linked to a pyrimidine ring through a CC or CN bond. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions.
Kingdom
Organic compounds
Super Class
Organoheterocyclic compounds
Class
Diazines
Sub Class
Pyrimidines and pyrimidine derivatives
Direct Parent
Phenylpyrimidines
Alternative Parents
Acetanilides / Pyrazolo[1,5-a]pyrimidines / Thiophene carboxylic acids and derivatives / Aryl ketones / Vinylogous amides / Tertiary carboxylic acid amides / Pyrazoles / Heteroaromatic compounds / Acetamides / Azacyclic compounds
show 3 more
Substituents
4-phenylpyrimidine / Acetanilide / Pyrazolo[1,5-a]pyrimidine / Anilide / Pyrazolopyrimidine / Aryl ketone / Thiophene carboxylic acid or derivatives / Monocyclic benzene moiety / Benzenoid / Azole
show 18 more
Molecular Framework
Aromatic heteropolycyclic compounds
External Descriptors
Not Available

Drug created on October 20, 2016 17:04 / Updated on August 02, 2018 06:40