GABA Agents

Name
GABA Agents
Accession Number
DBCAT000428
Description

Substances used for their pharmacological actions on GABAergic systems. GABAergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.

Drugs
DrugDrug Description
BaclofenA GABA-ergic agonist used to manage severe spasticity of cerebral or spinal origin in adult and pediatric patients.
LorazepamA long-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures.
TemazepamA short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and insomnia.
PentobarbitalA barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures.
Valproic acidAn anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
ClozapineAn antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients.
AlprazolamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression.
SecobarbitalA barbiturate used for the short-term treatment of insomnia.
ZolpidemA sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency.
PicrotoxinUsed internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates.
ChlordiazepoxideA benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period.
ThiopentalA barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure.
Clorazepic acidA benzodiazepine used to treat anxiety, partial seizures, and alcohol withdrawal.
MidazolamA short-acting injectable benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders.
FlurazepamA long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia.
DiazepamA long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.
ProgabideIndicated for the treatment of epilepsy.
OxazepamAn intermediate-acting benzodiazepine with slow onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawals, and insomnia.
MethylphenobarbitalFor the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy.
TriazolamA benzodiazepine used for short term treatment of insomnia.
TiagabineAn antiepileptic used to treat partial seizures.
ZaleplonA sedative used for short term treatment of insomnia in adults.
ClonazepamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures.
VigabatrinAn irreversible GABA transaminase inhibitor used as an adjunct to treat refractory complex partial seizures in patients ≥10 years unresponsive to alternatives. May also be used as monotherapy to treat infantile spasms in infants 1 month to 2 years.
ThiamylalUsed for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state.
PhenobarbitalA long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
FlumazenilA benzodiazepine antagonist that is used for the complete or partial reversal of the sedative effects caused by benzodiazepines in various clinical settings, such as induced general anesthesia for diagnostic and therapeutic procedures.
EstazolamA benzodiazepine used for the short-term management of insomnia.
AmobarbitalA barbiturate derivative used for the induction of sedation during procedures, short-term management of insomnia, and acute management of refractory tonic-clonic seizures.
HexobarbitalFor the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful...
BarbitalA long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice...
FlunitrazepamFor short-term treatment of severe insomnias, that are not responsive to other hypnotics.
BromazepamA short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety.
PrazepamFor the treatment of anxiety disorders.
NitrazepamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures.
Aminooxyacetic acidA compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem]
PagocloneFor the potential treatment of panic and anxiety disorders.
SGS-742Investigated for use/treatment in alzheimer's disease, attention deficit/hyperactivity disorder (ADHD), memory loss, and schizophrenia and schizoaffective disorders.
AZD 3355Investigated for use/treatment in gastroesophageal reflux disease (GERD).
ClomethiazoleInvestigated for use/treatment in strokes.
TramiprosateInvestigated for use/treatment in strokes and alzheimer's disease.
GaboxadolInvestigated for use/treatment in sleep disorders and insomnia.
AdipiplonInvestigated for use/treatment in insomnia and sleep disorders.
Arbaclofen PlacarbilInvestigated for the treatment of spasticity in multiple sclerosis, acute back spasms, and GERD.
ZolazepamZolazepam is a pyrazolodiazepinone derivative used as an anaesthetic in veterinary medicine. Zolazepam is typically used in combination with the NMDA antagonist tiletamine or the α2 adrenoceptor agonist xylazine. It...
BicucullineBicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and...
LesogaberanLesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others.
MuscimolMuscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease.
IndiplonIndiplon has been used in trials studying the treatment of Insomnia and Depression.
MedazepamNot Annotated
PhenibutNot Annotated
NordazepamAn intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam.
gamma-Aminobutyric acidThe most common inhibitory neurotransmitter in the central nervous system.
ClobazamA benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome.
PrimidoneAn antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures.
PyrazolamNot Annotated
PentetrazolNot Annotated
Drugs & Drug Targets
DrugTargetType
BaclofenGamma-aminobutyric acid type B receptor subunit 1target
BaclofenGamma-aminobutyric acid type B receptor subunit 2target
LorazepamTranslocator proteintarget
LorazepamUDP-glucuronosyltransferase 2B15enzyme
LorazepamGABA-A receptor (anion channel)target
LorazepamCytochrome P450 3A4enzyme
TemazepamTranslocator proteintarget
TemazepamGamma-aminobutyric acid receptor subunit alpha-1target
TemazepamGamma-aminobutyric acid receptor subunit alpha-2target
TemazepamGamma-aminobutyric acid receptor subunit alpha-3target
TemazepamGamma-aminobutyric acid receptor subunit alpha-4target
TemazepamGamma-aminobutyric acid receptor subunit alpha-5target
TemazepamGamma-aminobutyric acid receptor subunit alpha-6target
TemazepamGamma-aminobutyric acid receptor subunit beta-1target
TemazepamGamma-aminobutyric acid receptor subunit beta-2target
TemazepamGamma-aminobutyric acid receptor subunit beta-3target
TemazepamGamma-aminobutyric acid receptor subunit gamma-1target
TemazepamGamma-aminobutyric acid receptor subunit gamma-2target
TemazepamGamma-aminobutyric acid receptor subunit gamma-3target
TemazepamGamma-aminobutyric acid receptor subunit deltatarget
TemazepamGamma-aminobutyric acid receptor subunit epsilontarget
TemazepamGamma-aminobutyric acid receptor subunit pitarget
TemazepamGamma-aminobutyric acid receptor subunit rho-1target
TemazepamGamma-aminobutyric acid receptor subunit rho-2target
TemazepamGamma-aminobutyric acid receptor subunit thetatarget
TemazepamGamma-aminobutyric acid receptor subunit rho-3target
TemazepamCytochrome P450 3A4enzyme
TemazepamCytochrome P450 2B6enzyme
TemazepamCytochrome P450 2C9enzyme
TemazepamGABA-A receptor (anion channel)target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
PentobarbitalCytochrome P450 3A4enzyme
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
PentobarbitalNeuronal acetylcholine receptor subunit alpha-4target
PentobarbitalNeuronal acetylcholine receptor subunit alpha-7target
PentobarbitalGlutamate receptor 2target
PentobarbitalGlutamate receptor ionotropic, kainate 2target
PentobarbitalCytochrome P450 2C19enzyme
PentobarbitalCytochrome P450 2A6enzyme
PentobarbitalGABA-A receptor (anion channel)target
PentobarbitalNMDA receptortarget
PentobarbitalNuclear receptor subfamily 1 group I member 2target
Valproic acidHistone deacetylase 9target
Valproic acidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Valproic acidCytochrome P450 2A6enzyme
Valproic acidCytochrome P450 2B6enzyme
Valproic acidCytochrome P450 2C9enzyme
Valproic acidSolute carrier family 22 member 5transporter
Valproic acidSolute carrier family 22 member 6transporter
Valproic acidSolute carrier family 22 member 8transporter
Valproic acidMonocarboxylate transporter 1transporter
Valproic acidSolute carrier family 22 member 7transporter
Valproic acidCytochrome P450 3A5enzyme
Valproic acidUDP-glucuronosyltransferase 1-9enzyme
Valproic acidProstaglandin G/H synthase 1enzyme
Valproic acidCytochrome P450 1A2enzyme
Valproic acidCytochrome P450 2C19enzyme
Valproic acidCytochrome P450 3A4enzyme
Valproic acidUDP-glucuronosyltransferase 1-4enzyme
Valproic acidUDP-glucuronosyltransferase 1-8enzyme
Valproic acidUDP-glucuronosyltransferase 1-10enzyme
Valproic acidUDP-glucuronosyltransferase 1-6enzyme
Valproic acidUDP-glucuronosyltransferase 1-3enzyme
Valproic acidUDP-glucuronosyltransferase 2B7enzyme
Valproic acidUDP-glucuronosyltransferase 2B15enzyme
Valproic acid2-oxoglutarate dehydrogenase, mitochondrialtarget
Valproic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
Valproic acidSodium channel proteintarget
Valproic acidHistone deacetylase 2target
Valproic acidPeroxisome proliferator-activated receptor alphatarget
Valproic acidPeroxisome proliferator-activated receptor deltatarget
Valproic acidPeroxisome proliferator-activated receptor gammatarget
Valproic acidSerum albumincarrier
Valproic acidUDP-glucuronosyltransferase 1-1enzyme
Valproic acidSolute carrier organic anion transporter family member 2B1transporter
ClozapineDopamine D4 receptortarget
ClozapineHistamine H1 receptortarget
ClozapineDopamine D2 receptortarget
ClozapineNeuron-specific vesicular protein calcyontarget
ClozapineHistamine H4 receptortarget
Clozapine5-hydroxytryptamine receptor 2Atarget
Clozapine5-hydroxytryptamine receptor 1Atarget
Clozapine5-hydroxytryptamine receptor 2Ctarget
ClozapineDopamine D1 receptortarget
ClozapineCytochrome P450 1A2enzyme
ClozapineCytochrome P450 2D6enzyme
ClozapineDopamine D3 receptortarget
ClozapineMuscarinic acetylcholine receptor M1target
ClozapineMuscarinic acetylcholine receptor M2target
ClozapineMuscarinic acetylcholine receptor M3target
ClozapineMuscarinic acetylcholine receptor M4target
ClozapineMuscarinic acetylcholine receptor M5target
Clozapine5-hydroxytryptamine receptor 1Btarget
Clozapine5-hydroxytryptamine receptor 1Dtarget
Clozapine5-hydroxytryptamine receptor 1Etarget
Clozapine5-hydroxytryptamine receptor 3Atarget
Clozapine5-hydroxytryptamine receptor 6target
Clozapine5-hydroxytryptamine receptor 7target
ClozapineAlpha-1A adrenergic receptortarget
ClozapineAlpha-1B adrenergic receptortarget
ClozapineAlpha-2A adrenergic receptortarget
ClozapineAlpha-2B adrenergic receptortarget
ClozapineAlpha-2C adrenergic receptortarget
ClozapineCytochrome P450 2C9enzyme
ClozapineP-glycoprotein 1transporter
ClozapineCytochrome P450 3A4enzyme
ClozapineCytochrome P450 2C19enzyme
ClozapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
ClozapineUDP-glucuronosyltransferase 1-4enzyme
ClozapineCytochrome P450 1A1enzyme
ClozapineCytochrome P450 2A6enzyme
ClozapineCytochrome P450 2C8enzyme
ClozapineGlutathione S-transferase Ptarget
AlprazolamGamma-aminobutyric acid receptor subunit alpha-1target
AlprazolamGamma-aminobutyric acid receptor subunit alpha-6target
AlprazolamTranslocator proteintarget
AlprazolamGamma-aminobutyric acid receptor subunit alpha-3target
AlprazolamGamma-aminobutyric acid receptor subunit alpha-4target
AlprazolamGamma-aminobutyric acid receptor subunit alpha-5target
AlprazolamGamma-aminobutyric acid receptor subunit alpha-2target
AlprazolamCytochrome P450 3A4enzyme
AlprazolamCytochrome P450 2C9enzyme
AlprazolamCytochrome P450 3A5enzyme
AlprazolamCytochrome P450 3A7enzyme
AlprazolamGABA-A receptor (anion channel)target
AlprazolamSerum albumincarrier
Alprazolamalpha1-acid glycoproteincarrier
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
SecobarbitalCytochrome P450 2C8enzyme
SecobarbitalCytochrome P450 2C9enzyme
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
SecobarbitalNeuronal acetylcholine receptor subunit alpha-4target
SecobarbitalNeuronal acetylcholine receptor subunit alpha-7target
SecobarbitalGlutamate receptor 2target
SecobarbitalGlutamate receptor ionotropic, kainate 2target
SecobarbitalCytochrome P450 1A2enzyme
SecobarbitalNMDA receptortarget
SecobarbitalCytochrome P450 2C19enzyme
ZolpidemGamma-aminobutyric acid receptor subunit alpha-1target
ZolpidemCytochrome P450 3A4enzyme
ZolpidemCytochrome P450 1A2enzyme
ZolpidemGamma-aminobutyric acid receptor subunit alpha-2target
ZolpidemGamma-aminobutyric acid receptor subunit alpha-3target
ZolpidemCytochrome P450 2C9enzyme
ZolpidemCytochrome P450 2C19enzyme
ZolpidemCytochrome P450 2D6enzyme
ZolpidemGamma-aminobutyric acid receptor subunit gamma-2target
PicrotoxinGamma-aminobutyric acid receptor subunit rho-1target
PicrotoxinGamma-aminobutyric acid receptor subunit alpha-1target
PicrotoxinGlycine receptor subunit alpha-2target
PicrotoxinGlycine receptor subunit alpha-3target
PicrotoxinCytochrome P450 1A1enzyme
PicrotoxinGlutamine synthetaseenzyme
PicrotoxinGlycine receptor subunit alpha-1target
ChlordiazepoxideGABA-A receptor (anion channel)target
ThiopentalGamma-aminobutyric acid receptor subunit alpha-1target
ThiopentalFatty-acid amide hydrolase 1target
ThiopentalGamma-aminobutyric acid receptor subunit alpha-2target
ThiopentalGamma-aminobutyric acid receptor subunit alpha-3target
ThiopentalGamma-aminobutyric acid receptor subunit alpha-4target
ThiopentalGamma-aminobutyric acid receptor subunit alpha-5target
ThiopentalGamma-aminobutyric acid receptor subunit alpha-6target
ThiopentalNeuronal acetylcholine receptor subunit alpha-4target
ThiopentalNeuronal acetylcholine receptor subunit alpha-7target
ThiopentalGlutamate receptor 2target
ThiopentalGlutamate receptor ionotropic, kainate 2target
ThiopentalCytochrome P450 3A Subfamilyenzyme
ThiopentalMuscarinic acetylcholine receptor M3target
ThiopentalCytochrome P450 2C19enzyme
Clorazepic acidTranslocator proteintarget
Clorazepic acidCytochrome P450 3A4enzyme
Clorazepic acidGABA-A receptor (anion channel)target
MidazolamGamma-aminobutyric acid receptor subunit alpha-1target
MidazolamGamma-aminobutyric acid receptor subunit alpha-5target
MidazolamGamma-aminobutyric acid receptor subunit alpha-3target
MidazolamGamma-aminobutyric acid receptor subunit alpha-2target
MidazolamGamma-aminobutyric acid receptor subunit alpha-4target
MidazolamGamma-aminobutyric acid receptor subunit alpha-6target
MidazolamCytochrome P450 3A4enzyme
MidazolamCytochrome P450 3A5enzyme
MidazolamUDP-glucuronosyltransferase 1-4enzyme
MidazolamCytochrome P450 3A7enzyme
FlurazepamGamma-aminobutyric acid receptor subunit alpha-1target
FlurazepamGamma-aminobutyric acid receptor subunit beta-1target
FlurazepamGamma-aminobutyric acid receptor subunit beta-3target
FlurazepamGamma-aminobutyric acid receptor subunit alpha-5target
FlurazepamGamma-aminobutyric acid receptor subunit alpha-3target
FlurazepamGamma-aminobutyric acid receptor subunit alpha-2target
FlurazepamGamma-aminobutyric acid receptor subunit beta-2target
FlurazepamGamma-aminobutyric acid receptor subunit alpha-4target
FlurazepamGamma-aminobutyric acid receptor subunit alpha-6target
FlurazepamGamma-aminobutyric acid receptor subunit gamma-1target
FlurazepamGamma-aminobutyric acid receptor subunit gamma-2target
FlurazepamGamma-aminobutyric acid receptor subunit gamma-3target
FlurazepamGamma-aminobutyric acid receptor subunit deltatarget
FlurazepamGamma-aminobutyric acid receptor subunit epsilontarget
FlurazepamGamma-aminobutyric acid receptor subunit pitarget
FlurazepamGamma-aminobutyric acid receptor subunit rho-2target
FlurazepamGamma-aminobutyric acid receptor subunit thetatarget
FlurazepamGamma-aminobutyric acid receptor subunit rho-1target
FlurazepamCytochrome P450 3A4enzyme
FlurazepamGamma-aminobutyric acid receptor subunit rho-3target
FlurazepamP-glycoprotein 1transporter
FlurazepamCytochrome P450 2E1enzyme
FlurazepamCytochrome P450 2A6enzyme
FlurazepamSolute carrier family 22 member 2transporter
DiazepamTranslocator proteintarget
DiazepamGamma-aminobutyric acid receptor subunit alpha-1target
DiazepamGamma-aminobutyric acid receptor subunit alpha-2target
DiazepamGamma-aminobutyric acid receptor subunit alpha-3target
DiazepamCytochrome P450 3A4enzyme
DiazepamSerum albumincarrier
DiazepamCytochrome P450 2C9enzyme
DiazepamCytochrome P450 2C19enzyme
DiazepamCytochrome P450 3A5enzyme
DiazepamCytochrome P450 3A7enzyme
DiazepamGamma-aminobutyric acid receptor subunit alpha-5target
DiazepamGamma-aminobutyric acid receptor subunit beta-1target
DiazepamGamma-aminobutyric acid receptor subunit beta-2target
DiazepamGamma-aminobutyric acid receptor subunit beta-3target
DiazepamGamma-aminobutyric acid receptor subunit gamma-1target
DiazepamGamma-aminobutyric acid receptor subunit gamma-2target
DiazepamGamma-aminobutyric acid receptor subunit gamma-3target
DiazepamGamma-aminobutyric acid receptor subunit deltatarget
DiazepamGamma-aminobutyric acid receptor subunit epsilontarget
DiazepamGamma-aminobutyric acid receptor subunit pitarget
DiazepamGamma-aminobutyric acid receptor subunit rho-1target
DiazepamGamma-aminobutyric acid receptor subunit rho-2target
DiazepamGamma-aminobutyric acid receptor subunit rho-3target
DiazepamGamma-aminobutyric acid receptor subunit thetatarget
DiazepamP-glycoprotein 1transporter
DiazepamCytochrome P450 2B6enzyme
DiazepamProstaglandin G/H synthase 1enzyme
DiazepamCytochrome P450 2C18enzyme
DiazepamCytochrome P450 2C8enzyme
DiazepamCytochrome P450 2E1enzyme
DiazepamGABA-A receptor (anion channel)target
ProgabideGamma-aminobutyric acid receptor subunit alpha-1target
ProgabideGamma-aminobutyric acid type B receptor subunit 1target
OxazepamGamma-aminobutyric acid receptor subunit alpha-1target
OxazepamGamma-aminobutyric acid receptor subunit alpha-2target
OxazepamGamma-aminobutyric acid receptor subunit alpha-3target
OxazepamGamma-aminobutyric acid receptor subunit alpha-4target
OxazepamGamma-aminobutyric acid receptor subunit alpha-5target
OxazepamGamma-aminobutyric acid receptor subunit alpha-6target
OxazepamGamma-aminobutyric acid receptor subunit beta-1target
OxazepamGamma-aminobutyric acid receptor subunit beta-2target
OxazepamGamma-aminobutyric acid receptor subunit beta-3target
OxazepamGamma-aminobutyric acid receptor subunit gamma-1target
OxazepamGamma-aminobutyric acid receptor subunit gamma-2target
OxazepamGamma-aminobutyric acid receptor subunit gamma-3target
OxazepamGamma-aminobutyric acid receptor subunit deltatarget
OxazepamGamma-aminobutyric acid receptor subunit epsilontarget
OxazepamGamma-aminobutyric acid receptor subunit pitarget
OxazepamGamma-aminobutyric acid receptor subunit rho-1target
OxazepamGamma-aminobutyric acid receptor subunit rho-2target
OxazepamGamma-aminobutyric acid receptor subunit thetatarget
OxazepamGamma-aminobutyric acid receptor subunit rho-3target
OxazepamUDP-glucuronosyltransferase 2B15enzyme
OxazepamUDP-glucuronosyltransferase 2B7enzyme
OxazepamUDP-glucuronosyltransferase 1-9enzyme
OxazepamGABA-A receptor (anion channel)target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
MethylphenobarbitalCytochrome P450 2C19enzyme
MethylphenobarbitalCytochrome P450 2B6enzyme
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
MethylphenobarbitalGlutamate receptor 2target
MethylphenobarbitalGlutamate receptor ionotropic, kainate 2target
MethylphenobarbitalNuclear receptor subfamily 1 group I member 2target
TriazolamTranslocator proteintarget
TriazolamCytochrome P450 3A4enzyme
TriazolamCytochrome P450 3A5enzyme
TriazolamCytochrome P450 3A7enzyme
TriazolamGamma-aminobutyric acid receptor subunit alpha-1target
TriazolamGamma-aminobutyric acid receptor subunit alpha-2target
TriazolamGamma-aminobutyric acid receptor subunit alpha-3target
TriazolamGamma-aminobutyric acid receptor subunit alpha-4target
TriazolamGamma-aminobutyric acid receptor subunit alpha-5target
TriazolamGamma-aminobutyric acid receptor subunit alpha-6target
TriazolamGamma-aminobutyric acid receptor subunit beta-1target
TriazolamGamma-aminobutyric acid receptor subunit beta-2target
TriazolamGamma-aminobutyric acid receptor subunit beta-3target
TriazolamGamma-aminobutyric acid receptor subunit gamma-1target
TriazolamGamma-aminobutyric acid receptor subunit gamma-2target
TriazolamGamma-aminobutyric acid receptor subunit gamma-3target
TriazolamGamma-aminobutyric acid receptor subunit deltatarget
TriazolamGamma-aminobutyric acid receptor subunit epsilontarget
TriazolamGamma-aminobutyric acid receptor subunit pitarget
TriazolamGamma-aminobutyric acid receptor subunit rho-1target
TriazolamGamma-aminobutyric acid receptor subunit rho-2target
TriazolamGamma-aminobutyric acid receptor subunit rho-3target
TriazolamGamma-aminobutyric acid receptor subunit thetatarget
TriazolamCytochrome P450 2C8enzyme
TriazolamGABA-A receptor (anion channel)target
TiagabineSodium- and chloride-dependent GABA transporter 1target
TiagabineCytochrome P450 3A4enzyme
TiagabineUDP-glucuronosyltransferase 1-1enzyme
ZaleplonTranslocator proteintarget
ZaleplonGamma-aminobutyric acid receptor subunit alpha-1target
ZaleplonCytochrome P450 3A4enzyme
ZaleplonAldehyde oxidaseenzyme
ZaleplonCytochrome P450 3A5enzyme
ZaleplonCytochrome P450 3A7enzyme
ClonazepamTranslocator proteintarget
ClonazepamCytochrome P450 3A4enzyme
ClonazepamSerum albumincarrier
ClonazepamCytochrome P450 2E1enzyme
ClonazepamArylamine N-acetyltransferase 2enzyme
ClonazepamGABA-A receptor (anion channel)target
ClonazepamNuclear receptor subfamily 1 group I member 2target
Vigabatrin4-aminobutyrate aminotransferase, mitochondrialtarget
VigabatrinGamma-aminobutyric acid type B receptor subunit 1target
VigabatrinProton-coupled amino acid transporter 1transporter
VigabatrinCytochrome P450 2C9enzyme
ThiamylalGamma-aminobutyric acid receptor subunit alpha-1target
ThiamylalATP-sensitive inward rectifier potassium channel 8target
ThiamylalATP-sensitive inward rectifier potassium channel 11target
ThiamylalCytochrome P450 2C9enzyme
ThiamylalCytochrome P450 3A4enzyme
ThiamylalCytochrome P450 2E1enzyme
PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
PhenobarbitalCytochrome P450 2C19enzyme
PhenobarbitalCytochrome P450 2C9enzyme
PhenobarbitalCytochrome P450 2B6enzyme
PhenobarbitalCytochrome P450 2C8enzyme
PhenobarbitalCytochrome P450 1A2enzyme
PhenobarbitalCytochrome P450 3A4enzyme
PhenobarbitalCanalicular multispecific organic anion transporter 2transporter
PhenobarbitalBile salt export pumptransporter
PhenobarbitalP-glycoprotein 1transporter
PhenobarbitalMultidrug resistance-associated protein 1transporter
PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
PhenobarbitalCanalicular multispecific organic anion transporter 1transporter
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
PhenobarbitalGlutamate receptor 2target
PhenobarbitalGlutamate receptor ionotropic, kainate 2target
PhenobarbitalCytochrome P450 2A6enzyme
PhenobarbitalCytochrome P450 2E1enzyme
PhenobarbitalCytochrome P450 3A5enzyme
PhenobarbitalCytochrome P450 1A1enzyme
PhenobarbitalCytochrome P450 2C18enzyme
PhenobarbitalCytochrome P450 3A7enzyme
PhenobarbitalCytochrome P450 4B1enzyme
PhenobarbitalNMDA receptortarget
PhenobarbitalNuclear receptor subfamily 1 group I member 2target
PhenobarbitalUDP-glucuronosyltransferase 1-1enzyme
PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
FlumazenilGamma-aminobutyric acid receptor subunit alpha-1target
FlumazenilGamma-aminobutyric acid receptor subunit gamma-2target
FlumazenilGamma-aminobutyric acid receptor subunit alpha-5target
FlumazenilGABA-A receptor (anion channel)target
EstazolamCytochrome P450 3A4enzyme
EstazolamGamma-aminobutyric acid receptor subunit alpha-1target
EstazolamGamma-aminobutyric acid receptor subunit alpha-2target
EstazolamGamma-aminobutyric acid receptor subunit alpha-3target
EstazolamGamma-aminobutyric acid receptor subunit alpha-5target
EstazolamGamma-aminobutyric acid receptor subunit gamma-1target
EstazolamGamma-aminobutyric acid receptor subunit gamma-2target
EstazolamGamma-aminobutyric acid receptor subunit gamma-3target
EstazolamGamma-aminobutyric acid receptor subunit beta-1target
EstazolamGamma-aminobutyric acid receptor subunit beta-2target
EstazolamGamma-aminobutyric acid receptor subunit beta-3target
EstazolamGamma-aminobutyric acid receptor subunit deltatarget
EstazolamGamma-aminobutyric acid receptor subunit epsilontarget
EstazolamGamma-aminobutyric acid receptor subunit pitarget
EstazolamGamma-aminobutyric acid receptor subunit rho-1target
EstazolamGamma-aminobutyric acid receptor subunit rho-2target
EstazolamGamma-aminobutyric acid receptor subunit rho-3target
EstazolamGABA-A receptor (anion channel)target
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
AmobarbitalNeuronal acetylcholine receptor subunit alpha-4target
AmobarbitalNeuronal acetylcholine receptor subunit alpha-7target
AmobarbitalGlutamate receptor 2target
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
AmobarbitalGlutamate receptor ionotropic, kainate 2target
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
HexobarbitalCytochrome P450 2C9enzyme
HexobarbitalCytochrome P450 2C19enzyme
HexobarbitalProstaglandin G/H synthase 1enzyme
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
HexobarbitalNeuronal acetylcholine receptor subunit alpha-4target
HexobarbitalNeuronal acetylcholine receptor subunit alpha-7target
HexobarbitalGlutamate receptor 2target
HexobarbitalGlutamate receptor ionotropic, kainate 2target
BarbitalGamma-aminobutyric acid receptor subunit alpha-1target
BarbitalGamma-aminobutyric acid receptor subunit alpha-2target
BarbitalGamma-aminobutyric acid receptor subunit alpha-3target
BarbitalGamma-aminobutyric acid receptor subunit alpha-4target
BarbitalGamma-aminobutyric acid receptor subunit alpha-5target
BarbitalGamma-aminobutyric acid receptor subunit alpha-6target
BarbitalNeuronal acetylcholine receptor subunit alpha-4target
BarbitalNeuronal acetylcholine receptor subunit alpha-7target
BarbitalGlutamate receptor 2target
BarbitalGlutamate receptor ionotropic, kainate 2target
BarbitalCytochrome P450 3A4enzyme
BarbitalCytochrome P450 2C19enzyme
FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-2target
FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-4target
FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-5target
FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-6target
FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-3target
FlunitrazepamTranslocator proteintarget
FlunitrazepamCytochrome P450 2C19enzyme
FlunitrazepamUDP-glucuronosyltransferase 2B7enzyme
FlunitrazepamCytochrome P450 2A6enzyme
FlunitrazepamCytochrome P450 2B6enzyme
FlunitrazepamCytochrome P450 2C9enzyme
FlunitrazepamCytochrome P450 3A4enzyme
FlunitrazepamCytochrome P450 2E1enzyme
FlunitrazepamUDP-glucuronosyltransferase 1-1enzyme
FlunitrazepamUDP-glucuronosyltransferase 1-3enzyme
FlunitrazepamGamma-aminobutyric acid receptor subunit alpha-1target
FlunitrazepamGamma-aminobutyric acid receptor subunit beta-3target
FlunitrazepamGamma-aminobutyric acid receptor subunit gamma-2target
BromazepamGamma-aminobutyric acid receptor subunit alpha-2target
BromazepamGamma-aminobutyric acid receptor subunit alpha-1target
BromazepamGamma-aminobutyric acid receptor subunit alpha-3target
BromazepamGamma-aminobutyric acid receptor subunit alpha-4target
BromazepamGamma-aminobutyric acid receptor subunit alpha-5target
BromazepamGamma-aminobutyric acid receptor subunit alpha-6target
BromazepamGamma-aminobutyric acid receptor subunit beta-1target
BromazepamGamma-aminobutyric acid receptor subunit beta-2target
BromazepamGamma-aminobutyric acid receptor subunit beta-3target
BromazepamGamma-aminobutyric acid receptor subunit gamma-1target
BromazepamGamma-aminobutyric acid receptor subunit gamma-2target
BromazepamGamma-aminobutyric acid receptor subunit gamma-3target
BromazepamGamma-aminobutyric acid receptor subunit deltatarget
BromazepamGamma-aminobutyric acid receptor subunit epsilontarget
BromazepamGamma-aminobutyric acid receptor subunit pitarget
BromazepamGamma-aminobutyric acid receptor subunit rho-1target
BromazepamGamma-aminobutyric acid receptor subunit rho-2target
BromazepamGamma-aminobutyric acid receptor subunit thetatarget
BromazepamGamma-aminobutyric acid receptor subunit rho-3target
BromazepamCytochrome P450 1A2enzyme
BromazepamCytochrome P450 2C19enzyme
BromazepamCytochrome P450 2E1enzyme
PrazepamGamma-aminobutyric acid receptor subunit alpha-1target
PrazepamGamma-aminobutyric acid receptor subunit alpha-2target
PrazepamGamma-aminobutyric acid receptor subunit alpha-3target
PrazepamGamma-aminobutyric acid receptor subunit alpha-5target
PrazepamGamma-aminobutyric acid receptor subunit gamma-1target
PrazepamGamma-aminobutyric acid receptor subunit gamma-2target
PrazepamGamma-aminobutyric acid receptor subunit gamma-3target
PrazepamGamma-aminobutyric acid receptor subunit beta-1target
PrazepamGamma-aminobutyric acid receptor subunit beta-2target
PrazepamGamma-aminobutyric acid receptor subunit beta-3target
PrazepamGamma-aminobutyric acid receptor subunit deltatarget
PrazepamGamma-aminobutyric acid receptor subunit epsilontarget
PrazepamGamma-aminobutyric acid receptor subunit pitarget
PrazepamGamma-aminobutyric acid receptor subunit rho-1target
PrazepamGamma-aminobutyric acid receptor subunit rho-2target
PrazepamGamma-aminobutyric acid receptor subunit rho-3target
PrazepamCytochrome P450 3A4enzyme
PrazepamGABA-A receptor (anion channel)target
NitrazepamGamma-aminobutyric acid receptor subunit alpha-1target
NitrazepamSodium channel protein type 1 subunit alphatarget
NitrazepamGamma-aminobutyric acid receptor subunit alpha-2target
NitrazepamGamma-aminobutyric acid receptor subunit alpha-3target
NitrazepamGamma-aminobutyric acid receptor subunit alpha-4target
NitrazepamGamma-aminobutyric acid receptor subunit alpha-5target
NitrazepamGamma-aminobutyric acid receptor subunit alpha-6target
NitrazepamGamma-aminobutyric acid receptor subunit beta-1target
NitrazepamGamma-aminobutyric acid receptor subunit beta-2target
NitrazepamGamma-aminobutyric acid receptor subunit beta-3target
NitrazepamGamma-aminobutyric acid receptor subunit gamma-1target
NitrazepamGamma-aminobutyric acid receptor subunit gamma-2target
NitrazepamGamma-aminobutyric acid receptor subunit gamma-3target
NitrazepamGamma-aminobutyric acid receptor subunit deltatarget
NitrazepamGamma-aminobutyric acid receptor subunit epsilontarget
NitrazepamGamma-aminobutyric acid receptor subunit pitarget
NitrazepamGamma-aminobutyric acid receptor subunit rho-1target
NitrazepamGamma-aminobutyric acid receptor subunit rho-2target
NitrazepamGamma-aminobutyric acid receptor subunit rho-3target
NitrazepamGamma-aminobutyric acid receptor subunit thetatarget
NitrazepamCytochrome P450 3A4enzyme
NitrazepamCytochrome P450 2E1enzyme
Aminooxyacetic acidSerine--pyruvate aminotransferasetarget
PagocloneGamma-aminobutyric acid receptor subunit alpha-2target
PagocloneGamma-aminobutyric acid receptor subunit alpha-3target
SGS-742Gamma-aminobutyric acid type B receptor subunit 1target
SGS-742Gamma-aminobutyric acid type B receptor subunit 2target
AZD 3355Cellular tumor antigen p53target
ClomethiazoleGamma-aminobutyric acid receptor subunit alpha-1target
ClomethiazoleCytochrome P450 2A6enzyme
ClomethiazoleCytochrome P450 2B6enzyme
ClomethiazoleCytochrome P450 2C19enzyme
ClomethiazoleCytochrome P450 3A4enzyme
GaboxadolProton-coupled amino acid transporter 1transporter
AdipiplonGABA-A receptor (benzodiazepine site)target
Arbaclofen PlacarbilMonocarboxylate transporter 1transporter
Arbaclofen PlacarbilGamma-aminobutyric acid type B receptor subunit 1target
Arbaclofen PlacarbilGamma-aminobutyric acid type B receptor subunit 2target
MuscimolGamma-aminobutyric acid receptor subunit alpha-1target
MuscimolGamma-aminobutyric acid receptor subunit beta-3target
MuscimolGamma-aminobutyric acid receptor subunit gamma-2target
gamma-Aminobutyric acidGlycine amidinotransferase, mitochondrialtarget
gamma-Aminobutyric acidProton-coupled amino acid transporter 1transporter
gamma-Aminobutyric acidGamma-aminobutyric acid type B receptor subunit 1target
gamma-Aminobutyric acidGamma-aminobutyric acid type B receptor subunit 2target
ClobazamCytochrome P450 2C19enzyme
ClobazamCytochrome P450 3A4enzyme
ClobazamCytochrome P450 2B6enzyme
ClobazamCytochrome P450 2C18enzyme
ClobazamSodium- and chloride-dependent GABA transporter 1transporter
ClobazamSodium- and chloride-dependent GABA transporter 3transporter
ClobazamP-glycoprotein 1transporter
ClobazamGABA-A receptor (anion channel)target
ClobazamCytochrome P450 2D6enzyme
PrimidoneGamma-aminobutyric acid receptor subunit alpha-1target
PrimidoneCytochrome P450 2C19enzyme
PrimidoneCytochrome P450 2C9enzyme
PrimidoneCytochrome P450 3A4enzyme
PrimidoneGamma-aminobutyric acid receptor subunit alpha-2target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-3target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-4target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-5target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-6target
PrimidoneNeuronal acetylcholine receptor subunit alpha-4target
PrimidoneNeuronal acetylcholine receptor subunit alpha-7target
PrimidoneGlutamate receptor 2target
PrimidoneGlutamate receptor ionotropic, kainate 2target
PrimidoneGABA-A receptor (anion channel)target
PrimidoneTransient receptor potential cation channel subfamily M member 3transporter
PrimidoneCytochrome P450 2E1enzyme
PrimidoneCytochrome P450 1A2enzyme
PrimidoneUDP-glucuronosyltransferases (UGTs)enzyme