Monteplase

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Monteplase
Accession Number
DB12726
Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Other protein based therapies
Description

Monteplase has been used in trials studying the treatment of Pulmonary Embolism.

Protein chemical formula
Not Available
Protein average weight
Not Available
Sequences
Not Available
Synonyms
Not Available
Categories
UNII
0J4C69C6FB
CAS number
156616-23-8

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
(1,2,6,7-3H)Testosterone(1,2,6,7-3H)Testosterone may increase the anticoagulant activities of Monteplase.
(R)-warfarinThe risk or severity of bleeding can be increased when (R)-warfarin is combined with Monteplase.
(S)-WarfarinThe risk or severity of bleeding can be increased when (S)-Warfarin is combined with Monteplase.
1-Testosterone1-Testosterone may increase the anticoagulant activities of Monteplase.
18-methyl-19-nortestosterone18-methyl-19-nortestosterone may increase the anticoagulant activities of Monteplase.
3,5-Diiodotyrosine3,5-Diiodotyrosine may increase the anticoagulant activities of Monteplase.
4-hydroxycoumarinThe risk or severity of bleeding can be increased when 4-hydroxycoumarin is combined with Monteplase.
4-Hydroxytestosterone4-Hydroxytestosterone may increase the anticoagulant activities of Monteplase.
5beta-dihydrotestosterone5beta-dihydrotestosterone may increase the anticoagulant activities of Monteplase.
7,8-Dichloro-1,2,3,4-tetrahydroisoquinolineThe risk or severity of bleeding and hemorrhage can be increased when 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline is combined with Monteplase.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

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  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

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  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

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Food Interactions
  • Avoid herbs and supplements with anticoagulant/antiplatelet activity. Examples include garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba.

References

General References
Not Available
External Links
PubChem Substance
347911368
Wikipedia
Monteplase

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentPulmonary Embolism1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Taxonomy

Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available

Drug created on October 20, 2016 17:52 / Updated on July 10, 2020 21:43

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