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Identification
NameAcetylsalicylic acid
Accession NumberDB00945  (APRD00264, EXPT00475)
TypeSmall Molecule
GroupsApproved, Vet Approved
DescriptionThe prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Acetylsalicylic acid also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Structure
Thumb
Synonyms
2-(ACETYLOXY)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoic acid
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acide 2-(acetyloxy)benzoique
Acide acétylsalicylique
ácido acetilsalicílico
Acidum acetylsalicylicum
ASA
Aspirin
Azetylsalizylsaeure
Azetylsalizylsäure
Easprin
o-acetoxybenzoic acid
O-acetylsalicylic acid
o-carboxyphenyl acetate
Polopiryna
Salicylic acid acetate
External Identifiers Not Available
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
DurlazaCapsule, extended release162.5 mg/1OralNew Haven Pharmaceuticals, Inc.2015-09-16Not applicableUs
Approved Generic Prescription ProductsNot Available
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
7 Select Adult Chewable AspirinTablet, chewable81 mg/1Oral7 Eleven2014-08-05Not applicableUs
7 Select AspirinTablet325 mg/1Oral7 Eleven2014-08-05Not applicableUs
A.S.A.Tablet500 mgOralD.C. Labs Limited2001-12-222005-07-19Canada
A.S.A.Tablet325 mgOralD.C. Labs Limited2001-05-282005-07-19Canada
A.S.A. (acetylsalicylic Acid) Tab 325mg USPTablet325 mgOralAccurex Health Care Manufacturing Inc.1996-12-312003-01-28Canada
A.S.A. 325 Mg TabletTablet325 mgOralJamp Pharma Corporation2003-10-16Not applicableCanada
A.S.A. 80mg Acetylsalicylic Acid TabletsTablet80 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1995-12-312002-07-31Canada
A.S.A. Enteric Coated Tab 325mgTablet, delayed release325 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1987-12-312004-07-26Canada
A.S.A. Enteric Coated Tab 650mgTablet, delayed release650 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1987-12-312004-07-26Canada
A.S.A. Tablets 5gr BPTablet325 mgOralWestcan Pharmaceuticals Ltd.1997-09-081998-04-07Canada
Acetylsalicylic Acid 325mg Tablets USPTablet325 mgOralProdemdis Enr.2002-08-102010-07-15Canada
Acetylsalicylic Acid 325mg Tablets USPTablet325 mgOralPharmetics (2011) Inc2004-11-12Not applicableCanada
Acetylsalicylic Acid 80 Mg Chewable TabletsTablet80 mgOralJamp Pharma Corporation2006-10-26Not applicableCanada
Acetylsalicylic Acid A.S.A. Tablets 325mgTablet325 mgOralWestcan Pharmaceuticals Ltd.1996-02-072002-07-31Canada
Acetylsalicylic Acid Extra Strength 500mg Tablets USPTablet500 mgOralPharmetics (2011) Inc2004-11-19Not applicableCanada
Acetylsalicylic Acid Extra Strength Stomach Protection 500mg CapletsTablet500 mgOralPharmetics (2011) IncNot applicableNot applicableCanada
Acetylsalicylic Acid Stomach Protection 325mg TabletsTablet325 mgOralPharmetics (2011) IncNot applicableNot applicableCanada
Acetylsalicylic Acid Tab 300mgTablet300 mgOralPharmetics (2011) Inc1962-12-312006-07-27Canada
Acetylsalicylic Acid Tab 325mgTablet325 mgOralPharmel Inc1987-12-312016-10-25Canada
Acetylsalicylic Acid Tab 325mg BPTablet325 mgOralWes Pak Products Ltd.1995-12-312000-08-04Canada
Adult Low Dose AspirinTablet, delayed release81 mg/1OralA S Medication Solutions2007-01-12Not applicableUs
Adult Low Dose AspirinTablet, delayed release81 mg/1OralPharbest Pharmaceuticals, Inc.2007-01-12Not applicableUs
Adult Low Dose AspirinTablet, delayed release81 mg/1OralLiberty Pharmaceuticals, Inc.2007-01-12Not applicableUs
Adult Low Dose AspirinTablet, delayed release81 mg/1OralAidarex Pharmaceuticals LLC2007-01-12Not applicableUs
Adult Low Dose AspirinTablet, delayed release81 mg/1OralREMEDYREPACK INC.2015-06-15Not applicableUs
Adult Low Dose Aspirin Enteric Safety CoatedTablet, delayed release81 mg/1OralZandi LLC2011-01-18Not applicableUs
Adult Low Dose Enteric Coated AspirinTablet, coated81 mg/1OralPreferred Pharmaceuticals Inc.2015-10-06Not applicableUs
Adult Low Dose Enteric Coated AspirinTablet, coated81 mg/1OralREMEDYREPACK INC.2015-12-30Not applicableUs
Adult Low Dose Enteric Coated AspirinTablet, coated81 mg/1OralTYA Pharmaceuticals2000-07-01Not applicableUs
Adult Low Dose Enteric Coated AspirinTablet, coated81 mg/1OralGeri Care Pharmaceutical Corp2000-07-01Not applicableUs
Adult Low Strength AspirinTablet, coated81 mg/1OralBedrock Brands, Llc2004-01-14Not applicableUs
Adult Low Strength AspirinTablet, coated81 mg/1OralSafeway2004-01-14Not applicableUs
Adult Low Strength AspirinTablet, coated81 mg/1OralDolgencorp, LLC2004-01-14Not applicableUs
Adult Low Strength AspirinTablet, coated81 mg/1OralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED2004-01-142015-11-20Us
Adult Low Strength AspirinTablet, coated81 mg/1OralArmy and Air Force Exchange Service2004-01-142016-02-19Us
Adult Low Strength AspirinTablet, coated81 mg/1OralSUPERVALU INC.2004-01-142018-03-10Us
Adults Low Strength AspirinTablet81 mg/1OralGenvion Corporation2015-06-01Not applicableUs
Advanced AspirinTablet325 1/1OralAdvanced First Aid, Inc.2015-04-07Not applicableUs
Apo Asa Tab 325mgTablet325 mgOralApotex Inc1989-12-31Not applicableCanada
AsaTablet, delayed release81 mgOralPharmascience Inc2015-05-06Not applicableCanada
AsaTablet, chewable80 mgOralSanis Health IncNot applicableNot applicableCanada
Asa 325 Mg Tablets Regular StrengthTablet325 mgOralTanta Pharmaceuticals IncNot applicableNot applicableCanada
Asa 325mgTablet325 mgOralVita Health Products Inc1981-12-31Not applicableCanada
Asa 500 Mg Tablets Extra StrengthTablet500 mgOralTanta Pharmaceuticals Inc2013-05-02Not applicableCanada
Asa 80Tablet, chewable80 mgOralSorres Pharma Inc2009-02-262014-06-20Canada
Asa 80 mgTablet80 mgOralJamieson Laboratories LtdNot applicableNot applicableCanada
Asa 80mgTablet80 mgOralVita Health Products Inc1996-10-112004-07-26Canada
Asa 81 mgTablet, delayed release81 mgOralLaboratoires Trianon Inc2016-04-20Not applicableCanada
Asa 81 mgTablet, delayed release81 mgOralPharmascience Inc2001-11-30Not applicableCanada
Asa 81 mgTablet, delayed release81 mgOralVita Health Products Inc2012-01-12Not applicableCanada
Asa 975 TabTablet, delayed release975 mgOralPro Doc Limitee1983-12-311999-08-12Canada
Asa Acetylsalicylic AcidTablet325 mgOralLil' Drug Store Products Inc2013-11-12Not applicableCanada
Asa Acetylsalicylic AcidTablet325 mgOralGfr Pharma Ltd.2004-07-062011-07-15Canada
Asa Chewable TabletsTablet80 mgOralTherapharma Inc.Not applicableNot applicableCanada
Asa Daily Low DoseTablet, delayed release81 mgOralPharmascience Inc2001-04-03Not applicableCanada
Asa Daily Low DoseTablet, chewable81 mgOralPharmascience IncNot applicableNot applicableCanada
Asa ECTablet, delayed release80 mgOralSanis Health Inc2014-07-16Not applicableCanada
Asa ECTablet, delayed release81 mgOralSanis Health Inc2014-07-25Not applicableCanada
Asa EC 80Tablet, delayed release80 mgOralSorres Pharma Inc2009-02-262014-06-20Canada
Asa Ect 325mgTablet, delayed release325 mgOralShoppers Drug Mart Inc.1979-12-311998-08-14Canada
Asa Ect 600mgTablet, delayed release600 mgOralBionatal Drug Co1977-12-311999-07-14Canada
Asa Ect 650mgTablet, delayed release650 mgOralShoppers Drug Mart Inc.1978-12-311998-08-14Canada
Asa Ect 650mgTablet, delayed release650 mgOralD.C. Labs Limited1970-12-312005-07-19Canada
Asa Extra Strength Caplet 500mgTablet500 mgOralWestcan Pharmaceuticals Ltd.1996-10-112004-07-26Canada
Asa Extra Strength Tab 500mgTablet500 mgOralVita Health Products Inc1996-10-112007-07-30Canada
Asa Suppositories 150mgSuppository150 mgRectalPharmascience Inc1990-12-31Not applicableCanada
Asa Suppositories 650mgSuppository650 mgRectalPharmascience Inc1990-12-31Not applicableCanada
Asa Tab 325mgTablet325 mgOralShoppers Drug Mart Inc.1984-12-311997-08-15Canada
Asa Tab 325mgTablet325 mgOralDrug Trading Company Ltd.1951-12-311996-09-17Canada
Asa Tab 325mgTablet325 mgOralNovopharm Limited1978-12-312015-10-26Canada
Asa Tab 325mgTablet325 mgOralEverest Pharmaceuticals Ltd.1980-12-311999-07-14Canada
Asa Tab 325mgTablet325 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1957-12-312002-07-31Canada
Asa Tab 325mg Enteric CoatedTablet, delayed release325 mgOralD.C. Labs Limited1969-12-312005-07-19Canada
Asa Tablets USP 325 mgTablet325 mgOralPendopharm Division Of De Pharmascience Inc1971-12-312014-09-19Canada
Asa-325 Comprimes RetardTablet, delayed release325 mgOralPro Doc Limitee1959-12-311999-08-12Canada
Asa-650 Comprimes RetardTablet, delayed release650 mgOralPro Doc Limitee1978-12-311999-08-12Canada
Asadol 325mgTablet, delayed release325 mgOralPendopharm Division Of De Pharmascience Inc1993-12-312011-09-30Canada
Asadol 650mgTablet, delayed release650 mgOralPendopharm Division Of De Pharmascience Inc1993-12-312011-09-30Canada
AsaphenTablet, chewable80 mgOralPharmascience Inc1995-12-31Not applicableCanada
Asaphen E.C.Tablet, delayed release80 mgOralPharmascience Inc1998-12-03Not applicableCanada
Asaphen ECTablet, delayed release162 mgOralPharmascience Inc2003-09-02Not applicableCanada
Asaphen Plus 325Tablet325 mgOralPharmascience IncNot applicableNot applicableCanada
Asatab 80 Mg Chewable TabletsTablet, chewable80 mgOralOdan Laboratories Ltd2006-05-23Not applicableCanada
Asatab EC 325mgTablet, delayed release325 mgOralOdan Laboratories Ltd2010-06-11Not applicableCanada
Asatab EC 650mgTablet, delayed release650 mgOralOdan Laboratories Ltd2010-06-11Not applicableCanada
Ascriptin Maximum Strength Buffered AspirinTablet, film coated500 mg/1OralNovartis Consumer Health, Inc.2009-12-31Not applicableUs
Ascriptin Regular Strength Buffered AspirinTablet, film coated325 mg/1OralNovartis Consumer Health, Inc.2009-09-24Not applicableUs
Aspergum 325 Mg (cherry)Gum, chewing325 mgOralHeritage Brands, A Subsidiary Of Insight Pharmaceuticals Llc1985-01-012015-06-24Canada
Aspergum Orange 325 mgGum, chewing325 mgOralHeritage Brands, A Subsidiary Of Insight Pharmaceuticals Llc1985-01-012015-06-24Canada
Aspi-corTablet, coated81 mg/1OralL.N.K. International, Inc.2015-02-03Not applicableUs
Aspir LowTablet81 mg/1OralMajor Pharmaceuticals2011-05-24Not applicableUs
Aspir LowTablet81 mg/1OralUnit Dose Services2011-05-24Not applicableUs
Aspir LowTablet81 mg/1OralNu Care Pharmaceuticals, Inc.2011-05-24Not applicableUs
Aspir LowTablet81 mg/1OralCardinal Health2011-05-24Not applicableUs
Aspir LowTablet81 mg/1OralUnit Dose Services2011-05-24Not applicableUs
Aspir LowTablet81 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2011-05-24Not applicableUs
AspirinTablet, chewable81 mg/1OralAAA Pharmaceutical, Inc.2012-12-15Not applicableUs
AspirinTablet325 mg/1OralAtlantic Biologicals Corps1993-08-04Not applicableUs
AspirinTablet, film coated325 mg/1OralL&R Distributors, Inc.1996-02-10Not applicableUs
AspirinTablet, coated81 mg/1OralCVS Pharmacy2015-07-31Not applicableUs
AspirinTablet, film coated325 mg/1OralYichang Humanwell Pharmaceutical Co. Ltd.2016-10-312016-11-29Us
AspirinTablet, coated81 mg/1OralCispharma, Inc2011-02-14Not applicableUs
AspirinTablet, coated325 mg/1OralSafecor Health, LLC2014-09-30Not applicableUs
AspirinTablet, chewable81 mg/1OralMajor Pharmaceuticals2007-12-12Not applicableUs
AspirinTablet, delayed release81 mg/1OralMc Kesson2012-12-15Not applicableUs
AspirinTablet, chewable81 mg/1OralPublix Super Markets Inc1999-07-02Not applicableUs
AspirinTablet325 mg/1OralSt Mary's Medical Park Pharmacy1993-08-04Not applicableUs
AspirinTablet81 mg/1OralThe Kroger Co.2011-08-30Not applicableUs
AspirinTablet, delayed release81 mg/1OralSunrise Pharmaceutical Inc2010-01-03Not applicableUs
AspirinTablet325 mg/1OralGeri Care Pharmaceuticals, Corp1993-08-042017-12-30Us
AspirinTablet325 g/1OralApotheca, Inc1983-04-15Not applicableUs
AspirinTablet, film coated325 mg/1OralFRED'S, INC.1996-02-10Not applicableUs
AspirinTablet, coated81 mg/1OralRUGBY LABORATORIES, INC2014-01-14Not applicableUs
AspirinTablet, delayed release81 mg/1OralHy Vee Inc1997-06-25Not applicableUs
AspirinTablet, coated81 mg/1OralRite Aid2004-04-14Not applicableUs
AspirinTablet, film coated81 mg/1OralCARDINAL HEALTH, INC.2016-08-15Not applicableUs
AspirinTablet, coated325 mg/1OralMEIJER, INC.2014-06-30Not applicableUs
AspirinTablet81 mg/1OralAdvance Pharmaceutical Inc.1999-06-12Not applicableUs
AspirinTablet325 mg/1OralQualitest Pharmaceutical, Inc.2009-11-03Not applicableUs
AspirinTablet, chewable81 mg/1OralPublix Super Markets Inc1999-07-02Not applicableUs
AspirinTablet325 mg/1OralCVS Pharmacy2015-08-10Not applicableUs
AspirinTablet81 mg/1Oralbryant ranch prepack2008-04-28Not applicableUs
AspirinTablet, film coated325 mg/1OralL.N.K. International, Inc.1996-02-10Not applicableUs
AspirinTablet325 mg/1OralValu Merchandisers Company1993-08-04Not applicableUs
AspirinTablet, film coated325 mg/1OralChain Drug Consortium1996-02-10Not applicableUs
AspirinTablet325 mg/1OralRebel Distributors Corp2008-11-07Not applicableUs
AspirinTablet, coated81 mg/1OralNew World Imports, Inc2011-01-25Not applicableUs
AspirinTablet, coated81 mg/1OralCardinal Health2012-11-13Not applicableUs
AspirinTablet, chewable81 mg/1OralWestern Family Foods Inc1993-03-30Not applicableUs
AspirinTablet81 mg/1OralRugby Laboratories Inc.2008-04-28Not applicableUs
AspirinTablet, delayed release325 mg/1OralAAA Pharmaceutical, Inc.2012-12-15Not applicableUs
AspirinTablet81 mg/1OralCardinal Health2014-09-20Not applicableUs
AspirinTablet, coated81 mg/1OralBest Choice (Valu Merchandisers Company)2014-06-30Not applicableUs
AspirinSuppository300 mg/1RectalPaddock Laboratories, LLC1990-09-01Not applicableUs
AspirinTablet81 mg/1OralMajor Pharmaceuticals2010-07-16Not applicableUs
AspirinTablet, delayed release81 mg/1OralMc Kesson2012-12-15Not applicableUs
AspirinTablet325 mg/1OralUNITED EXCHANGE CORP.2016-03-02Not applicableUs
AspirinTablet325 mg/1OralHART Health1986-06-04Not applicableUs
AspirinTablet325 mg/1OralWin Co Foods, Llc1996-02-10Not applicableUs
AspirinTablet, coated81 mg/1OralAmerisource Bergen (Good Neighbor Pharmacy) 461222014-05-01Not applicableUs
AspirinTablet, coated81 mg/1OralWALGREEN CO.2004-01-14Not applicableUs
AspirinTablet325 mg/1OralH E B2006-02-10Not applicableUs
AspirinTablet81 mg/1OralAi Ping Pharmaceutical Inc.2014-01-30Not applicableUs
AspirinTablet, chewable81 mg/1OralAdvance Pharmaceutical Inc.1988-04-15Not applicableUs
AspirinTablet, film coated325 mg/1OralYichang Humanwell Pharmaceutical Co. Ltd.2016-10-312016-11-29Us
AspirinTablet, coated325 mg/1OralCispharma, Inc2010-11-15Not applicableUs
AspirinTablet, coated325 mg/1OralArmy and Air Force Exchange Service1996-02-10Not applicableUs
AspirinTablet, film coated325 mg/1OralMoore Medical LLC2008-12-30Not applicableUs
AspirinTablet81 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-08-05Not applicableUs
AspirinTablet, delayed release81 mg/1OralPublix Super Markets Inc2001-03-15Not applicableUs
AspirinTablet325 mg/1OralUnited Exchange Corporation1993-08-04Not applicableUs
AspirinTablet, film coated325 mg/1OralChain Drug Marketing Association Inc1996-02-10Not applicableUs
AspirinTablet, film coated325 mg/1OralContract Pharmacy Services Pa2010-08-10Not applicableUs
AspirinTablet, film coated325 mg/1OralBetter Living Brands, Llc1996-02-10Not applicableUs
AspirinTablet81 mg/1OralVelocity Pharma2011-04-01Not applicableUs
AspirinTablet81 mg/1OralThe Kroger Co.2014-06-30Not applicableUs
AspirinTablet325 mg/1OralHannaford Brothers Company1995-06-27Not applicableUs
AspirinTablet, delayed release81 mg/1OralH E B2004-08-03Not applicableUs
AspirinTablet, film coated325 mg/1OralCARDINAL HEALTH, INC.2016-08-15Not applicableUs
AspirinTablet, chewable81 mg/1OralHy Vee Inc1997-07-25Not applicableUs
AspirinTablet, chewable81 mg/1OralPublix Super Markets Inc1998-08-24Not applicableUs
AspirinTablet325 mg/1OralCVS Pharmacy2015-10-14Not applicableUs
AspirinTablet325 mg/1OralKareway Product, Inc.2011-11-23Not applicableUs
AspirinTablet, film coated325 mg/1OralL.N.K. International, Inc.1996-02-10Not applicableUs
AspirinTablet, coated325 ng/1OralLiberty Pharmaceuticals, Inc.2012-04-18Not applicableUs
AspirinTablet, chewable81 mg/1OralKroger Company1992-10-06Not applicableUs
AspirinTablet, coated81 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-01-14Not applicableUs
AspirinTablet, film coated81 mg/1OralYichang Humanwell Pharmaceutical Co. Ltd.2016-10-312016-11-29Us
AspirinTablet325 mg/1OralGenuine First Aid LLC2010-04-23Not applicableUs
AspirinTablet, coated81 mg/1OralCardinal Health2012-11-13Not applicableUs
AspirinTablet81 mg/1OralRugby Laboratories Inc.1998-01-23Not applicableUs
AspirinTablet, chewable81 mg/1OralAAA Pharmaceutical, Inc.2012-12-15Not applicableUs
AspirinTablet325 mg/1OralAthlete's Needs1993-08-04Not applicableUs
AspirinTablet, delayed release81 mg/1OralMc Kesson2012-12-15Not applicableUs
AspirinSuppository600 mg/1RectalPaddock Laboratories, LLC1990-09-01Not applicableUs
AspirinTablet, coated325 mg/1OralTIME CAP LABS INC2014-04-02Not applicableUs
AspirinTablet, chewable81 mg/1OralCVS Pharmacy1992-08-25Not applicableUs
AspirinTablet325 mg/1OralSave A Lot Food Stores, Ltd.1996-02-10Not applicableUs
AspirinTablet81 mg/1OralLake Erie Medical DBA Quality Care Products LLC2009-11-03Not applicableUs
AspirinTablet, chewable81 mg/1OralH E B1998-02-18Not applicableUs
AspirinTablet325 mg/1OralAi Ping Pharmaceutical, Inc.2014-01-31Not applicableUs
AspirinTablet, chewable81 mg/1OralCARDINAL HEALTH, INC.2016-08-15Not applicableUs
AspirinTablet, chewable81 mg/1OralMeijer Distribution Inc1996-11-26Not applicableUs
AspirinTablet325 mg/1OralAdvance Pharmaceutical Inc.2002-01-09Not applicableUs
AspirinTablet81 mg/1OralDIRECT RX2014-01-01Not applicableUs
AspirinTablet, extended release81 mg/1OralGemini Pharmaceuticals, Inc. dba Plus Pharmaceuticals2013-01-10Not applicableUs
AspirinTablet, chewable81 mg/1OralPhysicians Total Care, Inc.2007-11-01Not applicableUs
AspirinTablet325 mg/1OralRugby Laboratories1993-08-04Not applicableUs
AspirinTablet, coated325 mg/1OralAAA Pharmaceutical, Inc.2012-12-15Not applicableUs
AspirinTablet, film coated325 mg/1OralCardinal Health1996-02-10Not applicableUs
AspirinTablet, film coated325 mg/1OralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1996-02-10Not applicableUs
AspirinTablet325 mg/1OralCardinal Health2014-09-20Not applicableUs
AspirinTablet, coated81 mg/1OralQUALITY CHOICE (Chain Drug Marketing Association)2014-07-31Not applicableUs
AspirinTablet, film coated325 mg/1OralGreenbrier International, Inc.1996-02-102019-07-08Us
AspirinTablet, film coated325 mg/1OralGeri Care Pharmaceuticals, Corp1996-02-10Not applicableUs
AspirinTablet, chewable81 mg/1OralProficient Rx LP2007-12-12Not applicableUs
AspirinTablet325 mg/1OralL.N.K. International, Inc.1993-08-04Not applicableUs
AspirinTablet, coated81 mg/1OralPreferred Pharmaceuticals, Inc2010-06-28Not applicableUs
AspirinTablet81 mg/1OralBedrock Brands, LLC (ST. JOSEPH)2014-05-30Not applicableUs
AspirinTablet, film coated325 mg/1OralSUPERVALU INC.2006-02-10Not applicableUs
AspirinTablet, chewable81 mg/1OralMeijer Distribution Inc1992-08-27Not applicableUs
AspirinTablet, film coated325 mg/1OralBetter Living Brands, Llc2006-02-10Not applicableUs
AspirinTablet, coated325 mg/1OralREMEDYREPACK INC.2016-12-01Not applicableUs
AspirinTablet, coated325 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2009-09-30Not applicableUs
AspirinTablet325 mg/1OralPublix Super Markets Inc1988-09-15Not applicableUs
AspirinTablet325 mg/1OralCentral Texas Community Health Centers2014-07-31Not applicableUs
AspirinTablet, extended release81 mg/1OralProficient Rx LP2013-01-10Not applicableUs
AspirinTablet81 mg/1OralCarilion Materials Management2009-11-03Not applicableUs
AspirinTablet, film coated81 mg/1OralYichang Humanwell Pharmaceutical Co. Ltd.2016-10-312016-11-29Us
AspirinTablet, coated81 mg/1OralDolgencorp, LLC2004-04-14Not applicableUs
AspirinTablet, delayed release81 mg/1OralAAA Pharmaceutical, Inc.2012-12-15Not applicableUs
AspirinTablet, chewable81 mg/1OralCVS Pharmacy1997-02-20Not applicableUs
AspirinTablet, coated81 mg/1OralL&R Distributors, Inc.2008-02-12Not applicableUs
AspirinTablet, delayed release81 mg/1OralMc Kesson2012-12-15Not applicableUs
AspirinTablet325 mg/1OralState of Florida DOH Central Pharmacy2014-11-01Not applicableUs
AspirinTablet81 mg/1OralQualitest Pharmaceutical, Inc.2009-11-03Not applicableUs
AspirinTablet, delayed release325 mg/1OralTIME CAP LABORATORIES INC.2012-05-08Not applicableUs
AspirinTablet325 mg/1OralGreenbrier International, Inc.1993-08-04Not applicableUs
AspirinTablet, film coated325 mg/1OralSina Health Inc2011-07-25Not applicableUs
AspirinTablet, delayed release325 mg/1Oralbryant ranch prepack2012-05-08Not applicableUs
AspirinTablet, coated325 mg/1OralWal Mart Stores Inc1996-02-10Not applicableUs
AspirinTablet, coated81 mg/1OralWALGREEN CO.2009-03-18Not applicableUs
AspirinTablet325 mg/1OralWinder Laboratories, LLC2011-08-252016-03-16Us
AspirinTablet, chewable81 mg/1OralCARDINAL HEALTH, INC.2016-08-15Not applicableUs
AspirinTablet, film coated81 mg/1OralMeijer Distribution Inc1992-06-11Not applicableUs
AspirinTablet325 mg/1OralAdvance Pharmaceutical Inc.1990-05-08Not applicableUs
AspirinTablet, coated81 mg/1OralCare One (American Sales Company)2014-06-30Not applicableUs
AspirinTablet, film coated325 mg/1OralSalado Sales, Inc.1996-02-10Not applicableUs
AspirinTablet, chewable81 mg/1OralNew World Imports, Inc2011-08-31Not applicableUs
AspirinTablet325 mg/1OralRugby Laboratories1996-02-10Not applicableUs
AspirinTablet325 mg/1OralDolgencorp, LLC1993-08-04Not applicableUs
AspirinTablet, delayed release81 mg/1OralAAA Pharmaceutical, Inc.2012-12-15Not applicableUs
AspirinTablet325 mg/1OralCardinal Health2014-09-20Not applicableUs
AspirinTablet, film coated325 mg/1OralContract Pharmacy Services Pa2010-11-01Not applicableUs
AspirinTablet325 mg/1OralAllegiant Health2014-12-18Not applicableUs
AspirinTablet, coated325 mg/1OralThe Kroger Co.2011-01-10Not applicableUs
AspirinTablet, chewable81 mg/1OralCardinal Health1990-09-122016-05-31Us
AspirinTablet, film coated325 mg/1OralHIMPRIT PHARMACHEM PVT LTD2010-03-01Not applicableUs
AspirinTablet, coated325 mg/1OralILEX Consumer Products Group, LLC (ST. JOSEPH)2012-03-15Not applicableUs
AspirinTablet, delayed release81 mg/1OralMeijer Distribution Inc1993-08-26Not applicableUs
AspirinTablet, chewable81 mg/1OralHy Vee Inc1995-11-09Not applicableUs
AspirinTablet325 mg/1OralPhysicians Total Care, Inc.1995-02-27Not applicableUs
AspirinTablet, delayed release81 mg/1OralSunrise Pharmaceutical Inc2005-12-26Not applicableUs
AspirinTablet325 mg/1OralPure Tek Corporation2011-07-07Not applicableUs
AspirinTablet81 mg/1OralSt Marys Medical Park Pharmacy2014-05-22Not applicableUs
Aspirin - Children's Size - TabletsTablet80 mgOralBayer Inc Consumer Care1995-12-312013-07-19Canada
Aspirin - Children's Size 80mgTablet80 mgOralSterling Winthrop Inc.1950-12-311996-09-10Canada
Aspirin 325 mgTablet325 mg/1OralReliable 1 Laboratories Llc2015-11-01Not applicableUs
Aspirin 325 Mg ECTablet325 mg/1OralReliable 1 Laboratories Llc2015-11-01Not applicableUs
Aspirin 325mgTablet325 mg/1OralAfassco Inc.2015-03-31Not applicableUs
Aspirin 5 GrainTablet325 mg/1OralProvision Medical Products2015-03-31Not applicableUs
Aspirin 81 mgTablet, delayed release81 mg/1OralMeijer2011-04-01Not applicableUs
Aspirin 81 mgTablet, coated81 mg/1OralDolgencorp, LLC2008-02-12Not applicableUs
Aspirin 81 mgTablet, delayed release81 mg/1OralChain Drug Marketing Association2014-06-13Not applicableUs
Aspirin 81 mgTablet, coated81 mg/1OralH E B2008-02-12Not applicableUs
Aspirin 81 mgTablet, chewable81 mg/1OralReliable 1 Laboratories Llc2015-11-01Not applicableUs
Aspirin 81 Mg Enteric CoatedTablet81 mg/1OralReliable 1 Laboratories Llc2015-11-01Not applicableUs
Aspirin 81 Mg Low DoseTablet, coated81 mg/1OralMeijer2011-05-01Not applicableUs
Aspirin 81mgTablet, delayed release81 mgOralBayer Inc Consumer Care1998-09-02Not applicableCanada
Aspirin 81mg Adult Low DoseTablet, delayed release81 mg/1OralMeijer2011-04-01Not applicableUs
Aspirin 81mg Adult Low DoseTablet, delayed release81 mg/1OralTop Care2016-10-03Not applicableUs
Aspirin 81mg Quick ChewsTablet, chewable81 mgOralBayer Inc Consumer Care2007-05-22Not applicableCanada
Aspirin Adult Low DoseTablet, chewable81 mg/1OralMedicine Shoppe International Inc1997-05-22Not applicableUs
Aspirin Adult Low DoseTablet, coated81 mg/1OralGREAT LAKES WHOLESALE, MARKETING, & SALES, INC.2008-02-12Not applicableUs
Aspirin Adult Low DoseTablet, coated81 mg/1OralWal Mart Stores Inc2014-07-25Not applicableUs
Aspirin Adult Low StrengthTablet, delayed release81 mg/1OralValu Merchandisers Company (Best Choice)2010-07-26Not applicableUs
Aspirin Adult Low StrengthTablet, chewable81 mg/1OralWestern Family Foods Inc2001-09-18Not applicableUs
Aspirin Adult Low StrengthTablet, film coated81 mg/1OralWestern Family Foods Inc2004-05-19Not applicableUs
Aspirin Adult Low StrengthTablet, film coated81 mg/1OralH E B2005-03-22Not applicableUs
Aspirin Adult Low Strength AspirinTablet, coated81 mg/1OralAmerisource Bergen (Good Neighbor Pharmacy) 461222011-03-172018-06-30Us
Aspirin Arthritis Pain Relief 650 mgTablet, delayed release650 mgOralBayer Inc Consumer Care1998-08-202009-08-06Canada
Aspirin ChewableTablet81 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2007-12-12Not applicableUs
Aspirin ChewableTablet81 mg/1OralAllegiant Health2014-12-18Not applicableUs
Aspirin ChewableTablet81 mg/1OralMc Kesson Packaging Services A Business Unit Of Mc Kesson Corporation2014-12-18Not applicableUs
Aspirin Chewable Low DoseTablet, chewable81 mg/1OralWin Co Foods, Llc2014-12-15Not applicableUs
Aspirin Chewable Low DoseTablet, chewable81 mg/1OralChain Drug Consortium2001-09-04Not applicableUs
Aspirin Chewable TabletsTablet325 mgOralBayer Inc Consumer Care1994-12-311997-08-01Canada
Aspirin Chewable Tablets - 325mgTablet325 mgOralSterling Winthrop Inc.1994-12-311996-09-10Canada
Aspirin Chewable Tablets - 325mgTablet325 mgOralSterling Winthrop Inc.1994-12-311996-09-10Canada
Aspirin Chewable Tablets 325mgTablet325 mgOralBayer Inc Consumer Care1994-12-311997-08-01Canada
Aspirin Coated Caplets 325 mgTablet, delayed release; Tablet, extended release325 mgOralSterling Winthrop Inc.1993-12-311996-09-10Canada
Aspirin Coated Caplets 500mgTablet, delayed release; Tablet, extended release500 mgOralSterling Winthrop Inc.1993-12-311996-09-10Canada
Aspirin Coated for Delayed Release Extra StrengthTablet, delayed release500 mgOralBayer Inc Consumer Care1996-12-31Not applicableCanada
Aspirin Coated for Delayed Release Regular StrengthTablet, delayed release325 mgOralBayer Inc Consumer Care1995-12-31Not applicableCanada
Aspirin Delayed ReleaseTablet, delayed release81 mg/811OralTime Cap Labs, Inc2010-12-23Not applicableUs
Aspirin ECTablet, coated325 mg/1OralPhysicians Total Care, Inc.1993-09-10Not applicableUs
Aspirin ECTablet, coated81 mg/1OralPhysicians Total Care, Inc.2000-11-30Not applicableUs
Aspirin ECTablet, coated81 mg/1OralRebel Distributors Corp1993-01-01Not applicableUs
Aspirin ECTablet, coated81 mg/1OralAphena Pharma Solutions Tennessee, Llc1994-02-05Not applicableUs
Aspirin EntericTablet, coated325 mg/1OralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1992-12-14Not applicableUs
Aspirin Enteric CoatedTablet81 mg/1OralAllegiant Health2014-12-18Not applicableUs
Aspirin Enteric CoatedTablet325 mg/1OralChain Drug Consortium2014-10-27Not applicableUs
Aspirin Enteric CoatedTablet325 mg/1OralAllegiant Health2014-12-18Not applicableUs
Aspirin Enteric CoatedTablet, delayed release81 mg/1OralWestern Family Foods Inc2003-07-09Not applicableUs
Aspirin Enteric CoatedTablet, coated81 mg/1OralP & L Development, LLC2010-09-01Not applicableUs
Aspirin Enteric CoatedTablet, delayed release81 mg/1OralChain Drug Consortium, LLC2011-03-22Not applicableUs
Aspirin Enteric CoatedTablet, coated81 mg/1OralChain Drug Marketing Association Inc2011-05-01Not applicableUs
Aspirin Enteric CoatedTablet, coated81 mg/1OralCVS Pharmacy2011-05-01Not applicableUs
Aspirin Enteric CoatedTablet, coated81 mg/1OralFreds Inc2013-03-15Not applicableUs
Aspirin Enteric CoatedTablet, delayed release81 mg/1OralWestern Family Foods, Inc.2012-01-04Not applicableUs
Aspirin Enteric CoatedTablet, coated325 mg/1OralTarget Corporation2011-04-05Not applicableUs
Aspirin Enteric CoatedTablet, coated81 mg/1OralPublix Supermarkets, Inc.2013-01-04Not applicableUs
Aspirin Enteric Coated Caplet 325mgTablet, delayed release325 mgOralSterling Winthrop Inc.1993-12-311996-09-10Canada
Aspirin Enteric Coated Low DoseTablet, coated81 mg/1OralWalgreen Company2011-05-01Not applicableUs
Aspirin Enteric Coated Low DoseTablet, coated81 mg/1OralWalgreen Company2014-07-25Not applicableUs
Aspirin Enteric Coated, Regular StrengthTablet, coated325 mg/1OralWalgreen Company1992-12-14Not applicableUs
Aspirin Enteric Safety CoatedTablet, delayed release81 mg/1OralAvema Pharma Solutions2011-08-11Not applicableUs
Aspirin Enteric Safety CoatedTablet81 mg/1OralTOP CARE (Topco Associates LLC)2014-06-30Not applicableUs
Aspirin Enteric Safety CoatedTablet, delayed release81 mg/1OralCare One (American Sales Company)2010-07-15Not applicableUs
Aspirin Enteric Safety CoatedTablet81 mg/1OralCare One (American Sales Company)2014-04-30Not applicableUs
Aspirin Enteric Safety CoatedTablet, coated81 mg/1OralPublix Supermarkets, Inc.2013-08-15Not applicableUs
Aspirin Enteric Safety CoatedTablet81 mg/1OralWestern Family Foods, Inc.2012-01-04Not applicableUs
Aspirin Enteric Safety-coatedTablet81 mg/1OralTarget Corporation2013-03-08Not applicableUs
Aspirin Express PackGranule500 mgOralBayer Inc Consumer Care2008-01-212012-07-12Canada
Aspirin Extra StrengthTablet500 mgOralBayer Inc Consumer Care1995-12-31Not applicableCanada
Aspirin Extra StrengthTablet, coated500 mg/5001OralTime Cap Labs, Inc2013-02-11Not applicableUs
Aspirin Extra Strength 500mg Tab USPTablet500 mgOralSterling Winthrop Inc.1992-12-311996-09-10Canada
Aspirin Extra Strength PlusTablet500 mgOralBayer Inc Consumer CareNot applicableNot applicableCanada
Aspirin Extra Strength With Stomach GuardTablet500 mgOralBayer Inc Consumer CareNot applicableNot applicableCanada
Aspirin Extra Strength With Stomach GuardTablet500 mgOralBayer Inc Consumer CareNot applicableNot applicableCanada
Aspirin GranulesGranule500 mgOralBayer Inc Consumer CareNot applicableNot applicableCanada
Aspirin Low DoseTablet, film coated81 mg/1OralContract Pharmacy Services Pa2010-11-03Not applicableUs
Aspirin Low DoseTablet, chewable81 mg/1OralRite Aid Corporation2001-09-04Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralDolgencorp, LLC2014-07-25Not applicableUs
Aspirin Low DoseTablet, chewable81 mg/1OralChain Drug Consortium1990-09-12Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralArmy and Air Force Exchange Service2011-05-01Not applicableUs
Aspirin Low DoseTablet81 mg/1OralHarmon Store Inc.1990-09-12Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralSave A Lot Food Stores, Ltd.2011-05-01Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralChain Drug Consortium2011-05-01Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralDolgencorp, LLC2011-05-02Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralMedicine Shoppe International Inc2008-02-12Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralBetter Living Brands, Llc2011-05-01Not applicableUs
Aspirin Low DoseTablet, chewable81 mg/1OralValu Merchandisers Company2001-09-04Not applicableUs
Aspirin Low DoseTablet, chewable81 mg/1OralArmy and Air Force Exchange Service1990-09-12Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralHarmon Store Inc.2011-05-01Not applicableUs
Aspirin Low DoseTablet, film coated81 mg/1OralContract Pharmacy Services Pa2010-08-09Not applicableUs
Aspirin Low DoseTablet, chewable81 mg/1OralSUPERVALU INC.1990-09-12Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralFRED'S, INC.2011-05-01Not applicableUs
Aspirin Low DoseTablet81 mg/1OralAmerica Medic2012-05-15Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralWALGREEN CO.2004-04-14Not applicableUs
Aspirin Low DoseTablet, film coated81 mg/1OralContract Pharmacy Services Pa2010-08-17Not applicableUs
Aspirin Low DoseTablet, chewable81 mg/1OralKroger Company1997-06-17Not applicableUs
Aspirin Low DoseTablet, chewable81 mg/1OralL&R Distributors, Inc.1990-09-12Not applicableUs
Aspirin Low DoseTablet, delayed release81 mg/1OralHannaford Brothers Company2005-04-26Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralBetter Living Brands, Llc2014-07-25Not applicableUs
Aspirin Low DoseTablet81 mg/1OralL.N.K. International, Inc.1990-09-12Not applicableUs
Aspirin Low DoseTablet, film coated81 mg/1OralContract Pharmacy Services Pa2010-08-10Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralL.N.K. International, Inc.2011-05-01Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralCostco Wholesale Corporation2011-05-01Not applicableUs
Aspirin Low DoseTablet, delayed release81 mg/1OralWin Co Foods, Llc2014-12-15Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralL&R Distributors, Inc.2004-01-14Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralSUPERVALU INC.2014-07-25Not applicableUs
Aspirin Low DoseTablet, chewable81 mg/1OralBetter Living Brands, Llc1990-09-12Not applicableUs
Aspirin Low DoseTablet, chewable81 mg/1OralBetter Living Brands, Llc1990-09-12Not applicableUs
Aspirin Low DoseTablet, coated81 mg/1OralL.N.K. International, Inc.2011-05-02Not applicableUs
Aspirin Low Dose ChewableTablet, chewable81 mg/1OralTime Cap Labs, Inc2010-07-16Not applicableUs
Aspirin Low Dose ChewableTablet, chewable81 mg/1OralBetter Living Brands, Llc2001-09-14Not applicableUs
Aspirin Low Dose ChewableTablet, chewable81 mg/1OralContract Pharmacy Services Pa2010-08-09Not applicableUs
Aspirin Low Dose ChewableTablet, chewable81 mg/1OralSafecor Health, LLC2014-09-30Not applicableUs
Aspirin Low Dose Enteric CoatedTablet, coated81 mg/1OralClinical Solutions Wholesale2010-06-28Not applicableUs
Aspirin Low Dose Enteric CoatedTablet, coated81 mg/1OralTime Cap Labs, Inc2010-06-28Not applicableUs
Aspirin Low Dose Enteric CoatedTablet, coated81 mg/1OralMc Kesson Packaging Services Business Unit Of Mc Kesson Corporation2012-11-13Not applicableUs
Aspirin Low Dose Enteric CoatedTablet81 mg/1OralTime Cap Labs, Inc2010-07-16Not applicableUs
Aspirin Low Dose Enteric CoatedTablet81 mg/1OralSMART SENSE (Kmart)2013-03-31Not applicableUs
Aspirin Low Dose Safety CoatedTablet, coated81 mg/1OralCardinal Health (Leader)2013-04-13Not applicableUs
Aspirin Low Dose Safety CoatedTablet81 mg/1OralP And L Development Of New York Corporation (Ready In Case)2014-07-31Not applicableUs
Aspirin Low Dose Safety CoatedTablet, coated81 mg/1OralHy Vee2013-03-15Not applicableUs
Aspirin Low Dose Safety CoatedTablet, coated81 mg/1OralGeiss, Destin & Dunn, Inc (Goodsense)2013-03-15Not applicableUs
Aspirin Low Dose Safety CoatedTablet, coated81 mg/1OralTOP CARE (Topco Associates LLC)2013-03-15Not applicableUs
Aspirin Low Dose Safety CoatedTablet, coated81 mg/1OralFreds Inc2013-03-08Not applicableUs
Aspirin Low Dose Safety CoatedTablet81 mg/1OralASSURED / DOLLAR TREE (Greenbrier International, Inc.)2013-03-31Not applicableUs
Aspirin Low Dose Safety CoatedTablet, coated81 mg/1OralAmerisource Bergen (Good Neighbor Pharmacy) 461222013-03-15Not applicableUs
Aspirin Low Dose Safety CoatedTablet81 mg/1OralBest Choice (Valu Merchandisers Company)2013-03-08Not applicableUs
Aspirin Low Dose Safety CoatedTablet81 mg/1OralPreferred Plus (Kinray)2013-03-31Not applicableUs
Aspirin Low Dose Safety CoatedTablet, coated81 mg/1OralWestern Family Foods, Inc.2013-03-01Not applicableUs
Aspirin Low Dose Safety CoatedTablet, coated81 mg/1OralHealthy Accents (DZA Brands, LLC)2013-03-01Not applicableUs
Aspirin Low Dose Safety CoatedTablet, coated81 mg/1OralBJWC (Berkley & Jensen / BJ's)2013-03-31Not applicableUs
Aspirin Low Dose Safety CoatedTablet, coated81 mg/1OralChain Drug Consortium, LLC2013-03-15Not applicableUs
Aspirin Low Dose Safety CoatedTablet81 mg/1OralP & L Development, LLC2013-03-01Not applicableUs
Aspirin Low Dose Safety CoatedTablet81 mg/1OralThe Kroger Co.2013-03-08Not applicableUs
Aspirin Low Dose Sugar FreeTablet, coated81 mg/1OralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED2011-05-01Not applicableUs
Aspirin Low StrengthTablet, coated81 mg/1OralCVS Pharmacy2014-07-25Not applicableUs
Aspirin Low Strength AdultTablet, coated81 mg/1OralSam's West Inc2011-05-01Not applicableUs
Aspirin Low Strength AdultTablet, coated81 mg/1OralSam's West Inc2008-02-12Not applicableUs
Aspirin Low Strength, EntericTablet, coated81 mg/1OralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED2004-04-14Not applicableUs
Aspirin MigraineTablet500 mgOralBayer Inc Consumer CareNot applicableNot applicableCanada
Aspirin NsaidTablet325 mg/1OralREMEDYREPACK INC.2009-09-24Not applicableUs
Aspirin NsaidTablet325 mg/1OralGeri Care Pharmaceuticals, Corp1993-08-04Not applicableUs
Aspirin NsaidTablet, film coated325 mg/1OralValu Merchandisers Company1996-02-10Not applicableUs
Aspirin Regular StrengthTablet325 mg/1OralCVS Pharmacy1991-06-15Not applicableUs
Aspirin Regular StrengthTablet, coated325 mg/1OralMeijer2014-11-07Not applicableUs
Aspirin Regular StrengthTablet, coated325 mg/1OralCare One (American Sales Company)2011-08-02Not applicableUs
Aspirin Regular StrengthTablet, coated325 mg/1OralSuper Valu (Equaline)2011-12-05Not applicableUs
Aspirin Regular StrengthTablet325 mgOralBayer Inc Consumer Care1970-12-31Not applicableCanada
Aspirin Regular StrengthTablet325 mg/1OralKroger Company1987-11-15Not applicableUs
Aspirin Regular StrengthTablet, delayed release325 mg/1OralSUPERVALU INC.2014-10-01Not applicableUs
Aspirin Regular StrengthTablet325 mg/1OralSam's West Inc1996-02-10Not applicableUs
Aspirin Regular StrengthTablet325 mg/1OralMeijer Distribution Inc1987-07-15Not applicableUs
Aspirin Regular StrengthTablet, film coated325 mg/1OralWALGREEN CO.1996-02-10Not applicableUs
Aspirin Regular StrengthTablet, film coated325 mg/1OralCare One1996-02-10Not applicableUs
Aspirin Regular StrengthTablet, coated325 mg/1OralArmy and Air Force Exchange Service1992-12-14Not applicableUs
Aspirin Regular StrengthTablet, coated325 mg/1OralEQUATE (Walmart Stores, Inc.)2013-10-25Not applicableUs
Aspirin Regular StrengthTablet, coated325 mg/1OralAmerisource Bergen Drug Corporation (Good Neighbor Pharmacy) 243852011-11-17Not applicableUs
Aspirin Regular StrengthTablet, coated325 mg/1OralSMART SENSE (Kmart)2011-04-30Not applicableUs
Aspirin Regular Strength Regular StrengthTablet325 mg/1OralA S Medication Solutions Llc2006-05-24Not applicableUs
Aspirin Regular Strength Regular StrengthTablet325 mg/1OralMajor Pharmaceuticals2006-05-24Not applicableUs
Aspirin Safety CoatedTablet, coated81 mg/1OralFreds Inc2014-08-31Not applicableUs
Aspirin Safety CoatedTablet, coated81 mg/1OralWestern Family Foods, Inc.2014-05-01Not applicableUs
Aspirin Safety CoatedTablet, coated325 mg/1OralCVS Pharmacy2014-06-30Not applicableUs
Aspirin Safety CoatedTablet, coated325 mg/1OralHy Vee2014-05-31Not applicableUs
Aspirin Safety Coated Adult Low DoseTablet, delayed release81 mg/1OralWin Co Foods, Llc2014-12-15Not applicableUs
Aspirin Stomach Guard Extra StrengthTablet500 mgOralBayer Inc Consumer Care2009-10-09Not applicableCanada
Aspirin Stomach Guard Regular StrengthTablet325 mgOralBayer Inc Consumer Care2010-03-11Not applicableCanada
Aspirin Tab 325mg USPTablet325 mgOralSterling Winthrop Inc.1992-12-311996-09-10Canada
Aspirin Tablets 325mgTablet325 mgOralSterling Winthrop Inc.1992-12-311996-09-10Canada
Aspirin Thin CoatedTablet325 mg/1OralMajor Pharmaceuticals2014-05-07Not applicableUs
AsprinTablet, delayed release81 mg/1OralAvema Pharma Solutions2010-01-02Not applicableUs
Assured AspirinTablet, delayed release81 mg/1OralSpirit Pharmaceuticals LLC2016-07-01Not applicableUs
Astrin 5grTablet, delayed release325 mgOralMedic Laboratory LtÉe1959-12-311996-09-09Canada
BayerTablet325 mg/1OralLil' Drug Store Products, Inc.2009-07-01Not applicableUs
Bayer Advanced Aspirin Extra StrengthTablet500 mg/1OralBayer Health Care Llc, Consumer Care2012-12-01Not applicableUs
Bayer Advanced Aspirin Regular StrengthTablet325 mg/1OralBayer Corporation Consumer Care Division2010-12-01Not applicableUs
Bayer AspirinTablet325 mg/1OralNavajo Manufacturing Company Inc.2016-09-23Not applicableUs
Bayer Aspirin Extra Strength CapletsTablet500 mg/1OralBayer Health Care Llc, Consumer Care2014-12-23Not applicableUs
Bayer Aspirin Regimen Chewable Low Dose Aspirin OrangeTablet, chewable81 mg/1OralBayer Health Care Llc, Consumer Care2015-01-11Not applicableUs
Bayer Aspirin Regimen Regular StrengthTablet, chewable325 mg/1OralBayer Health Care Llc, Consumer Care2015-01-11Not applicableUs
Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry FlavoredTablet, chewable81 mg/1OralBayer Health Care Llc2002-07-02Not applicableUs
Bayer Fast ReleasePowder500 mg/1OralBayer Corporation Consumer Care Division2010-06-30Not applicableUs
Bayer Genuine AspirinTablet325 mg/1OralYour Safety Company2016-03-15Not applicableUs
Bayer Genuine AspirinTablet, coated325 mg/1OralUnifirst First Aid Corporation2014-01-24Not applicableUs
Bayer Genuine AspirinTablet325 mg/1OralR J General Corporation2014-07-31Not applicableUs
Bayer Genuine AspirinTablet325 mg/1OralBayer Health Care Consumer Care2014-07-31Not applicableUs
Bayer Low DoseTablet81 mg/1OralBayer Health Care Llc, Consumer Care2002-07-12Not applicableUs
Bayer Plus Extra StrengthTablet, coated500 mg/1OralBayer Health Care Llc, Consumer Care2015-01-12Not applicableUs
Berkley and Jensen AspirinTablet325 mg/1OralBJWC2008-07-23Not applicableUs
Buffered AspirinTablet325 mg/1OralRite Aid1990-03-30Not applicableUs
Buffered Aspirin Regular StrengthTablet, film coated325 mg/1OralCVS Pharmacy1990-03-30Not applicableUs
BufferinTablet325 mgOralNovartis Consumer Health Canada Inc.1986-12-312013-01-15Canada
BufferinTablet325 mg/1OralDr. Reddy's Laboratories Inc.2013-05-15Not applicableUs
Bufferin ArthritisTablet325 mg/1OralDr. Reddy's Laboratories Inc.2016-07-20Not applicableUs
Bufferin Extra -strengthTablet500 mgOralNovartis Consumer Health Canada Inc.1986-12-312013-01-15Canada
Bufferin Low Dose Buffered AspirinTablet81 mg/1OralNovartis Consumer Health, Inc.2011-03-11Not applicableUs
Care One AspirinTablet, chewable81 mg/1OralAmerican Sales Company2004-06-01Not applicableUs
Care One AspirinTablet325 mg/1OralAmerican Sales Company2004-05-18Not applicableUs
Care One AspirinTablet, chewable81 mg/1OralAmerican Sales Company2005-11-22Not applicableUs
Careall AspirinTablet, chewable81 mg/1OralNew World Imports, Inc2016-03-29Not applicableUs
Careall AspirinTablet, coated81 mg/1OralNew World Imports, Inc2016-03-01Not applicableUs
Chewable Adult Low Dose AspirinTablet, chewable81 mg/1OralRaritan Pharmaceuticals Inc2013-06-03Not applicableUs
Chewable AspirinTablet, chewable81 mg/1OralChain Drug Marketing Association2014-06-13Not applicableUs
Chewable AspirinTablet, chewable81 mg/1OralGenuine First Aid LLC2010-04-02Not applicableUs
Chewable AspirinTablet, chewable81 mg/1OralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1990-09-12Not applicableUs
Chewable Aspirin Low DoseTablet, chewable81 mg/1OralSMART SENSE (Kmart)2011-06-30Not applicableUs
Chewable Aspirin Low DoseTablet81 mg/1OralChain Drug Marketing Association Inc2001-09-04Not applicableUs
Chewable Daily Low Dose AsaTablet, chewable81 mgOralPharmascience Inc2008-10-31Not applicableCanada
Chewable Low Dose AspirinTablet, chewable81 mg/1OralFamily Dollar Services Inc1990-09-12Not applicableUs
Chewable Low Dose AspirinTablet, chewable81 mg/1OralSUPERVALU INC.2001-09-04Not applicableUs
Chronic Pain/fever ReliefTablet81 mg/1OralWe Care Distributor Inc.2016-02-09Not applicableUs
Coated Aspirin - Ect 80mgTablet, delayed release80 mgOralBayer Inc Consumer Care1996-10-021998-09-28Canada
Coated Aspirin Low-doseTablet, coated81 mg/1OralTarget Corporation2009-05-01Not applicableUs
Coated Daily Low Dose Asa 81 mgTablet, delayed release81 mgOralApotex Inc2013-10-17Not applicableCanada
Coated Daily Low-dose AsaTablet, delayed release81 mgOralPharmascience Inc2004-06-072010-04-30Canada
Coryphen 325 TabTablet, delayed release325 mgOralRougier Pharma Division Of Ratiopharm Inc1979-12-311999-09-27Canada
Coryphen 650 TabTablet, delayed release650 mgOralRougier Pharma Division Of Ratiopharm Inc1979-12-311999-09-27Canada
Critical Care Aspirin To GoPowder325 mg/1OralBreakthrough Products Inc.2012-10-01Not applicableUs
Dg Health AspirinTablet, chewable81 mg/1OralDolgencorp, LLC2009-12-04Not applicableUs
Direct Safety AspirinTablet, film coated325 mg/1OralConney Safety Products, LLC2013-05-03Not applicableUs
EC-81aspirin Enteric CoatedTablet81 mg/1OralTri Marc Labs2010-08-11Not applicableUs
EcotrinTablet, coated81 mg/1OralMedtech Products Inc.2012-06-01Not applicableUs
EcotrinTablet, coated81 mg/1OralMedtech Products Inc.2012-06-01Not applicableUs
Ecotrin Regular StrengthTablet, coated325 mg/1OralMedtech Products Inc.2012-06-01Not applicableUs
Enteric AspirinTablet, coated325 mg/1OralCostco Wholesale Corporation1992-12-14Not applicableUs
Enteric AspirinTablet, coated325 mg/1OralChain Drug Marketing Association Inc1992-12-14Not applicableUs
Enteric AspirinTablet, coated325 mg/1OralGREAT LAKES WHOLESALE, MARKETING, & SALES, INC.1992-12-14Not applicableUs
Enteric Aspirin Regular StrengthTablet, coated325 mg/1OralL.N.K. International, Inc.1992-12-14Not applicableUs
Enteric Coated A.S.aTablet, delayed release325 mgOralPendopharm Division Of De Pharmascience Inc2005-07-19Not applicableCanada
Enteric Coated A.S.aTablet, delayed release650 mgOralPendopharm Division Of De Pharmascience Inc2005-07-29Not applicableCanada
Enteric Coated A.S.a (caplet)Tablet, delayed release325 mgOralPendopharm Division Of De Pharmascience IncNot applicableNot applicableCanada
Enteric Coated A.S.A. (caplet)Tablet, delayed release650 mgOralPendopharm Division Of De Pharmascience IncNot applicableNot applicableCanada
Enteric Coated Asa 325 mgTablet, delayed release325 mgOralPendopharm Division Of De Pharmascience Inc2007-06-01Not applicableCanada
Enteric Coated Asa 325 mgTablet, delayed release325 mgOralGfr Pharma Ltd.2004-09-152010-06-29Canada
Enteric Coated Asa 650 mgTablet, delayed release650 mgOralGfr Pharma Ltd.2004-09-152010-06-29Canada
Enteric Coated Asa Tablets 325mgTablet, delayed release325 mgOralApotex Inc1982-12-31Not applicableCanada
Enteric Coated Asa Tablets 325mgTablet, delayed release325 mgOralVita Health Products Inc1993-12-31Not applicableCanada
Enteric Coated Asa Tablets 650mgTablet, delayed release650 mgOralApotex Inc1982-12-31Not applicableCanada
Enteric Coated Asa Tablets 650mgTablet, delayed release650 mgOralVita Health Products Inc1993-12-31Not applicableCanada
Enteric Coated AspirinTablet, delayed release325 mg/1OralRUGBY LABORATORIES, INC2011-09-20Not applicableUs
Enteric Coated AspirinTablet325 mg/1OralState of Florida DOH Central Pharmacy2014-01-01Not applicableUs
Enteric Coated AspirinTablet81 mg/1OralNash Finch Company2008-02-12Not applicableUs
Enteric Coated AspirinTablet, delayed release325 mg/1OralREMEDYREPACK INC.2010-04-23Not applicableUs
Enteric Coated AspirinTablet325 mg/1OralQualitest Pharmaceuticals2011-02-04Not applicableUs
Enteric Coated AspirinTablet325 mg/1OralAmerican Health Packaging2014-09-18Not applicableUs
Enteric Coated AspirinTablet325 mg/1OralA S Medication Solutions Llc2011-02-04Not applicableUs
Enteric Coated AspirinTablet325 mg/1OralA S Medication Solutions Llc2011-02-04Not applicableUs
Enteric Coated AspirinTablet, delayed release325 mg/1OralRebel Distributors Corp2011-09-20Not applicableUs
Enteric Coated Aspirin Regular StrengthTablet, delayed release325 mg/3251OralCardinal Health2013-06-28Not applicableUs
Enteric Coated Aspirin Regular StrengthTablet, coated325 mg/1OralL&R Distributors, Inc.1992-12-14Not applicableUs
Enteric Coated Aspirin Regular StrengthTablet, delayed release325 mg/1OralSafeway2015-08-05Not applicableUs
Enteric Coated Aspirin Regular StrengthTablet, coated325 mg/1OralGood Sense (Geiss, Destin & Dunn, Inc.)2011-08-22Not applicableUs
Enteric Coated Aspirin Regular StrengthTablet, coated325 mg/1OralP & L Development, LLC2016-03-31Not applicableUs
Enteric Coated Aspirin Regular StrengthTablet, delayed release325 mg/3251OralMcKesson Packaging Services a business unit of McKesson Corporation2013-06-28Not applicableUs
Enteric Coated Aspirin Regular StrengthTablet, coated325 mg/1OralBest Choice (Valu Merchandisers Company)2011-11-11Not applicableUs
Enteric Coated Aspirin Regular StrengthTablet, coated325 mg/1OralMc Kesson (Sunmark)2010-09-15Not applicableUs
Enteric Coated Aspirin Regular StrengthTablet, delayed release325 mg/3251OralCardinal Health2013-06-28Not applicableUs
Enteric Coated Aspirin Regular StrengthTablet, delayed release325 mg/3251OralTime Cap Labs, Inc2011-01-04Not applicableUs
Enteric Coated Daily Low Dose Asa 81mgTablet, delayed release81 mgOralVita Health Products Inc2011-06-27Not applicableCanada
Enteric Safety Coated AspirinTablet, coated81 mg/1OralRite Aid2004-01-14Not applicableUs
EntrophenTablet, delayed release81 mgOralPendopharm Division Of De Pharmascience Inc2000-06-20Not applicableCanada
Entrophen 325mg CapletsTablet, delayed release325 mgOralPendopharm Division Of De Pharmascience Inc1993-12-31Not applicableCanada
Entrophen 325mg TabletsTablet, delayed release325 mgOralPendopharm Division Of De Pharmascience Inc1951-12-31Not applicableCanada
Entrophen 650mg Caplet EctTablet, delayed release650 mgOralPendopharm Division Of De Pharmascience Inc1991-12-31Not applicableCanada
Entrophen 80mgTablet80 mgOralPendopharm Division Of De Pharmascience IncNot applicableNot applicableCanada
Entrophen ChewableTablet, chewable81 mgOralPendopharm Division Of De Pharmascience Inc2001-11-01Not applicableCanada
Entrophen Ect 500mgTablet, delayed release500 mgOralPendopharm Division Of De Pharmascience Inc1990-12-31Not applicableCanada
Entrophen Ect 650mgTablet, delayed release650 mgOralPendopharm Division Of De Pharmascience Inc1967-12-31Not applicableCanada
Entrophen Ect 975mgTablet, delayed release975 mgOralPendopharm Division Of De Pharmascience Inc1978-12-31Not applicableCanada
Equaline AspirinTablet325 mg/1OralSupervalu Inc2004-08-13Not applicableUs
Equaline AspirinTablet, chewable81 mg/1OralSupervalu Inc2004-08-30Not applicableUs
Equaline Aspirin Adult Low DoseTablet, chewable81 mg/1OralSupervalu Inc2004-08-21Not applicableUs
Equate AspirinTablet, chewable81 mg/1OralWal Mart Stores Inc2003-03-19Not applicableUs
Equate AspirinTablet325 mg/1OralWal Mart Stores Inc1990-02-15Not applicableUs
Equate Aspirin ChewableTablet, chewable81 mg/1OralWal Mart Stores Inc2003-03-06Not applicableUs
Equate Daily Low-doseTablet, delayed release81 mgOralPharmascience Inc2001-09-19Not applicableCanada
Euro AsaTablet80 mgOralEuro Pharm International Canada IncNot applicableNot applicableCanada
Euro Asa 325mg Chewable TabletTablet, chewable325 mgOralEuro Pharm International Canada IncNot applicableNot applicableCanada
Euro-asa Chewable TabletTablet, chewable80 mgOralEuro Pharm International Canada Inc2004-04-02Not applicableCanada
Euro-asa ECTablet, delayed release80 mgOralSandoz Canada Incorporated2014-10-01Not applicableCanada
Exact Coated Daily Low-dose AsaTablet, delayed release81 mgOralPharmascience Inc2002-03-01Not applicableCanada
Extra Strength Asa 500mgTablet500 mgOralJamp Pharma Corporation2006-02-16Not applicableCanada
FasprinTablet, orally disintegrating81 mg/1OralNobel Laboratories, LLC2006-09-20Not applicableUs
Flanax Aspirin Pain RelieverTablet325 mg/1OralBelmora LLC2012-12-062016-11-04Us
Formucare AspirinTablet, delayed release81 mg/1OralAccess Business Group International LLC2006-02-27Not applicableUs
Genuine AspirinTablet, film coated325 mg/1OralCVS Pharmacy2001-05-172019-07-08Us
Good Neighbor Pharmacy AspirinTablet, chewable81 mg/1OralAmerisource Bergen1997-06-26Not applicableUs
Good Neighbor Pharmacy AspirinTablet, film coated81 mg/1OralAmerisource Bergen2004-10-19Not applicableUs
Good Neighbor Pharmacy AspirinTablet325 mg/1OralAmerisource Bergen1989-09-15Not applicableUs
Good Neighbor Pharmacy AspirinTablet, chewable81 mg/1OralAmerisource Bergen1993-03-19Not applicableUs
Good Neighbor Pharmacy AspirinTablet325 mg/1OralAmerisource Bergen2015-02-20Not applicableUs
Good Neighbor Pharmacy Aspirin Enteric Safety CoatedTablet, delayed release81 mg/1OralAmerisource Bergen1994-03-29Not applicableUs
Good Neighbor Pharmacy Aspirin Orange Flavor ChewableTablet, chewable81 mg/1OralAmerisource Bergen2002-02-20Not applicableUs
Good Sense AspirinTablet, chewable81 mg/1OralL. Perrigo Company1992-11-04Not applicableUs
Good Sense AspirinTablet, chewable81 mg/1OralL Perrigo Company1997-08-08Not applicableUs
Good Sense AspirinTablet, film coated81 mg/1OralL Perrigo Company1993-07-09Not applicableUs
Good Sense AspirinTablet325 mg/1OralL. Perrigo Company1991-04-15Not applicableUs
Good Sense AspirinTablet, chewable81 mg/1OralL. Perrigo Company1999-08-25Not applicableUs
Good Sense Aspirin Enteric Safety CoatedTablet, delayed release81 mg/1OralL Perrigo Company1993-09-30Not applicableUs
Handy Solutions Genuine Aspirin BayerTablet325 mg/1OralNavajo Manufacturing Company Inc.2013-08-21Not applicableUs
Headache Tab 300mgTablet300 mgOralLaboratoire Romilo1979-12-311999-08-18Canada
Health Mart AspirinTablet325 mg/1OralMc Kesson2011-11-21Not applicableUs
Health Mart AspirinTablet, chewable81 mg/1OralMc Kesson2013-08-13Not applicableUs
Health Mart AspirinTablet, chewable81 mg/1OralMc Kesson2011-11-21Not applicableUs
Health Mart AspirinTablet, chewable81 mg/1OralMc Kesson2011-11-21Not applicableUs
Health Mart Regular Strength Enteric Coated AspirinTablet, coated325 mg/1OralMc Kesson (Health Mart)2012-06-05Not applicableUs
Health Sense Adult Chewable Low Strength AspirinTablet, chewable81 mg/1OralPrime Marketing, LLC2006-10-01Not applicableUs
Health Sense Aspirin 81Tablet, coated81 mg/1OralPrime Marketing, LLC2006-07-01Not applicableUs
Health Sense EcpirinTablet, coated325 mg/1OralPrime Marketing, LLC2006-12-01Not applicableUs
Healthy Accents AspirinTablet, chewable81 mg/1OralDZA Brands LLC2011-06-06Not applicableUs
Healthy Accents AspirinTablet325 mg/1OralDZA Brands LLC2008-01-22Not applicableUs
Healthy Accents AspirinTablet, chewable81 mg/1OralDZA Brands LLC2008-02-04Not applicableUs
Healthy Accents AspirinTablet, delayed release81 mg/1OralDZA Brands LLC2008-03-23Not applicableUs
Henry Schein AspirinTablet, film coated325 mg/1OralHenry Schein, Inc.2011-07-25Not applicableUs
Jamp-A.S.A.Tablet, delayed release80 mgOralJamp Pharma Corporation2006-09-28Not applicableCanada
Jamp-asa 81mg ECTablet, delayed release81 mgOralVita Health Products Inc2015-01-13Not applicableCanada
Kroger Value AspirinTablet325 mg/1OralKroger Company2007-03-17Not applicableUs
Leader AspirinTablet, chewable81 mg/1OralCardinal Health1993-08-09Not applicableUs
Leader AspirinTablet, chewable81 mg/1OralCardinal Health2014-09-20Not applicableUs
Leader AspirinTablet, coated325 mg/1OralCardinal Health (Leader) 372052012-04-092017-12-31Us
Leader AspirinTablet325 mg/1OralCardinal Health1990-05-15Not applicableUs
Leader AspirinTablet, chewable81 mg/1OralCardinal Health1997-04-02Not applicableUs
Leader Cardinal Health AspirinTablet, delayed release81 mg/1OralCardinal Health2001-08-22Not applicableUs
Leader Low Dose AspirinTablet, chewable81 mg/1OralCardinal Health2014-09-20Not applicableUs
Leader Low Dose AspirinTablet, chewable81 mg/1OralREMEDYREPACK INC.2016-08-02Not applicableUs
Lo-asa 80mg Chewable - TabTablet80 mgOralKinsmor Pharmaceuticals Canada Inc.1997-01-092000-06-16Canada
London Drugs Coated Daily Low-dose AsaTablet, delayed release81 mgOralPharmascience Inc2001-10-232014-08-04Canada
Low Dose AspirinTablet, chewable81 mg/1OralWALGREEN CO.1990-09-12Not applicableUs
Low Dose AspirinTablet, chewable81 mg/1OralNash Finch Company2001-09-04Not applicableUs
Low Dose AspirinTablet, chewable81 mg/1OralPharbest Pharmaceuticals, Inc.2007-08-22Not applicableUs
Low Dose AspirinTablet, chewable81 mg/1OralWalgreen Company2001-09-04Not applicableUs
Low Dose AspirinTablet81 mg/1OralSUPERVALU INC.2008-02-12Not applicableUs
Low Dose AspirinTablet81 mg/1OralQualitest Pharmaceuticals2009-11-03Not applicableUs
Low Dose AspirinTablet81 mg/1OralWal Mart Stores Inc2008-02-12Not applicableUs
Low Dose AspirinTablet81 mg/1OralPharmadel LLC2013-03-25Not applicableUs
Low Dose AspirinTablet81 mg/1OralPreferred Pharmaceuticals, Inc.2013-06-06Not applicableUs
Low Dose AspirinTablet, chewable81 mg/1OralGREAT LAKES WHOLESALE, MARKETING, & SALES, INC.1990-09-12Not applicableUs
Low Dose AspirinTablet, coated81 mg/1OralTIME CAP LABORATORIES, INC2015-06-19Not applicableUs
Low Dose Aspirin 81 Mg Safety CoatedTablet, delayed release81 mg/1OralFamily Dollar (FAMILY WELLNESS)2014-07-31Not applicableUs
Low Dose Aspirin Enteric Safety CoatedTablet, delayed release81 mg/1OralTime Cap Labs, Inc2010-08-11Not applicableUs
Low Dose Aspirin Enteric Safety CoatedTablet, delayed release81 mg/1OralTime Cap Labs, Inc2010-08-10Not applicableUs
Low Dose Aspirin Low DoseTablet, delayed release81 mg/1OralSMART SENSE (Kmart)2011-06-30Not applicableUs
Low Dose Chewable AspirinTablet, chewable81 mg/1OralNash Finch Company1990-09-12Not applicableUs
Low Dose Miniprin Enteric Safety CoatedTablet, delayed release81 mg/1OralTime Cap Labs, Inc2010-08-11Not applicableUs
Low Strength Chewable AspirinTablet, chewable81 mg/1OralGeri Care Pharmaceutical Corp1995-01-01Not applicableUs
LowprinTablet, chewable80 mgOralSandoz Canada Incorporated2009-10-02Not applicableCanada
Lowprin 325Tablet325 mgOralEuro Pharm International Canada IncNot applicableNot applicableCanada
Lowprin 325 Chewable TabletTablet, chewable325 mgOralEuro Pharm International Canada IncNot applicableNot applicableCanada
Lowprin 80mgTablet80 mgOralEuro Pharm International Canada Inc2009-10-06Not applicableCanada
M-asa 80 Mg CroquableTablet, chewable80 mgOralMantra Pharma Inc2015-02-11Not applicableCanada
Medi First Plus AspirinTablet, film coated325 mg/1OralUnifirst First Aid Corporation2008-12-30Not applicableUs
Medi-first AspirinTablet, film coated325 mg/1OralUnifirst First Aid Corporation2008-12-30Not applicableUs
Medique AspirinTablet, film coated325 mg/1OralUnifirst First Aid Corporation2008-12-30Not applicableUs
MedpurineTablet81 mg/1OralPURINEPHARMA LLC2015-04-14Not applicableUs
Micro-coated AspirinTablet, coated325 mg/1OralRUGBY LABORATORIES, INC2011-09-21Not applicableUs
MiniprinTablet, coated81 mg/1OralTIME CAP LABORATORIES, INC2012-05-07Not applicableUs
North AspirinTablet325 1/1OralNorth Safety Products2011-11-07Not applicableUs
NovasenTablet, delayed release650 mgOralTeva Canada Limited1976-12-31Not applicableCanada
NovasenTablet, delayed release325 mgOralTeva Canada Limited1976-12-31Not applicableCanada
Pain Relief AspirinTablet, film coated325 mg/1OralRite Aid Corporation2006-02-10Not applicableUs
Pain Relief Aspirin Low DoseTablet, coated81 mg/1OralRite Aid2008-02-12Not applicableUs
Pain Relief Aspirin Low DoseTablet, chewable81 mg/1OralRite Aid Corporation1990-09-12Not applicableUs
Pain Relief Aspirin Low DoseTablet, coated81 mg/1OralRite Aid2014-07-25Not applicableUs
Pain RelieverTablet, delayed release81 mg/1OralHealth Life Of Usa2016-02-09Not applicableUs
Pharbest Aspirin 325mgTablet, delayed release325 mg/1OralA S Medication Solutions Llc2010-09-20Not applicableUs
Pharbest Aspirin 325mgTablet, delayed release325 mg/1OralPharbest Pharmaceuticals, Inc.2010-09-20Not applicableUs
Pharbest Regular Strength AspirinTablet325 mg/1OralA S Medication Solutions Llc2007-01-12Not applicableUs
Pharbest Regular Strength AspirinTablet325 mg/1OralPharbest Pharmaceuticals, Inc2007-01-12Not applicableUs
PHL-asaTablet80 mgOralPharmel Inc2003-04-21Not applicableCanada
PHL-asa E.C.Tablet, delayed release80 mgOralPharmel Inc2003-04-21Not applicableCanada
Plus Pharma Nsaid 325 mgTablet81 mg/1OralTYA Pharmaceuticals2014-09-29Not applicableUs
Plus Pharma Nsaid AspirinTablet325 mg/1OralGemini Pharmaceuticals, Inc. dba Plus Pharma2006-03-27Not applicableUs
PMS-asaTablet80 mgOralPharmascience Inc2006-08-15Not applicableCanada
PMS-asaTablet81 mgOralPharmascience Inc2006-08-15Not applicableCanada
PMS-asaTablet325 mgOralPharmascience Inc1969-12-31Not applicableCanada
PMS-asa ECTablet, delayed release325 mgOralPharmascience Inc2006-08-31Not applicableCanada
PMS-asa ECTablet, delayed release650 mgOralPharmascience Inc2006-08-15Not applicableCanada
PMS-asa ECTablet, delayed release80 mgOralPharmascience Inc2006-08-15Not applicableCanada
PMS-asa ECTablet, delayed release325 mgOralPharmascience Inc2006-09-28Not applicableCanada
Praxis Asa EC 81 Mg Daily Low DoseTablet, delayed release81 mgOralPharmascience Inc2006-08-15Not applicableCanada
Pro-aas - 80 (croquable)Tablet, chewable80 mgOralPro Doc Limitee2008-07-03Not applicableCanada
Pro-aas EC - 80Tablet, delayed release80 mgOralPro Doc Limitee2008-07-03Not applicableCanada
Rapid Comfort AspirinTablet, film coated325 mg/1OralLab Safety Supply, Inc.2011-10-14Not applicableUs
Regular Strength AspirinTablet, coated325 mg/1OralWal Mart Stores Inc1992-12-14Not applicableUs
Regular Strength Aspirin ECTablet, delayed release325 mg/1OralProficient Rx LP2011-09-09Not applicableUs
Regular Strength Aspirin ECTablet, delayed release325 mg/1OralAidarex Pharmaceuticals LLC2011-09-09Not applicableUs
Regular Strength Aspirin ECTablet, delayed release325 mg/1OralMajor Pharmaceuticals Inc2011-09-09Not applicableUs
Regular Strength Aspirin ECTablet, delayed release325 mg/1OralClinical Solutions Wholesale2011-09-09Not applicableUs
Regular Strength Aspirin ECTablet, delayed release325 mg/1OralH.J. Harkins Company, Inc.2011-09-09Not applicableUs
Regular Strength Aspirin ECTablet, delayed release325 mg/1OralAphena Pharma Solutions Tennessee, Llc2011-09-09Not applicableUs
Regular Strength Aspirin ECTablet, delayed release325 mg/1OralLake Erie Medical DBA Quality Care Products LLC2011-09-09Not applicableUs
Regular Strength Aspirin ECTablet, delayed release325 mg/1OralMajor Pharmaceuticals Inc2011-09-09Not applicableUs
Regular Strength Aspirin ECTablet, delayed release325 mg/1OralREMEDYREPACK INC.2015-04-17Not applicableUs
Regular Strength Aspirin ECTablet, delayed release325 mg/1OralNcs Health Care Of Ky, Inc Dba Vangard Labs2011-09-09Not applicableUs
Regular Strength Enteric Coated AspirinTablet, coated325 mg/1OralNu Care Pharmaceuticals, Inc.2000-07-01Not applicableUs
Regular Strength Enteric Coated AspirinTablet, coated325 mg/1OralGeri Care Pharmaceutical Corp2000-07-01Not applicableUs
Regular Strength Enteric Coated AspirinTablet, coated325 mg/1OralAvera Mc Kennan Hospital2015-03-23Not applicableUs
Regular Strength Enteric Coated AspirinTablet, coated325 mg/1OralPreferred Pharmaceuticals Inc.2015-10-07Not applicableUs
Regular Strength Pain ReliefTablet, coated325 mg/1OralRite Aid Corporation1992-12-14Not applicableUs
Regular Strength Tri-buffered AspirinTablet, film coated325 mg/1OralWALGREEN CO.1990-03-30Not applicableUs
Relief Asa Extra StrengthTablet500 mgOralPendopharm Division Of De Pharmascience Inc2003-02-012016-10-25Canada
Rexall AspirinTablet, chewable81 mg/1OralDolgencorp, LLC2010-08-19Not applicableUs
Rexall Coated Daily Low Dose AsaTablet, delayed release81 mgOralPharmascience Inc2001-09-202016-10-28Canada
Rivasa 80mg Croquable - TabTablet, chewable80 mgOralLaboratoire Riva Inc1999-12-01Not applicableCanada
Rivasa 81 Mg ECTablet, delayed release81 mgOralLaboratoire Riva Inc2014-03-20Not applicableCanada
Rivasa FcTablet80 mgOralLaboratoire Riva Inc2004-01-01Not applicableCanada
Rugby AspirinTablet, chewable81 mg/1OralRugby Laboratories2014-03-21Not applicableUs
Rx Act AspirinTablet, chewable81 mg/1OralH E B1997-05-29Not applicableUs
Safety Coated AspirinTablet81 mg/1OralCare One (American Sales Company)2010-07-30Not applicableUs
Safety Coated AspirinTablet81 mg/1OralValu Merchandisers Company (Best Choice)2010-08-21Not applicableUs
Safety Coated Low Dose AspirinTablet, coated81 mg/1OralFamily Dollar Services Inc2008-02-12Not applicableUs
Shoprite AspirinTablet, chewable81 mg/1OralWakefern Food Corporation2016-10-17Not applicableUs
Smart Health Aspirin Regular StrengthTablet325 mg/1OralL Perrigo Company2003-04-09Not applicableUs
Smart Sense AspirinTablet, chewable81 mg/1OralKmart Corporation2010-06-04Not applicableUs
Smart Sense AspirinTablet, film coated81 mg/1OralKmart Corporation2010-10-17Not applicableUs
Smart Sense AspirinTablet325 mg/1OralKmart Corporation2010-06-04Not applicableUs
Smart Sense AspirinTablet, chewable81 mg/1OralKmart Corporation2010-06-04Not applicableUs
Smart Sense Chewable AspirinTablet, chewable81 mg/1OralKmart Corporation2016-03-14Not applicableUs
Smart Sense Chewable AspirinTablet, chewable81 mg/1OralKmart Corporation2016-08-23Not applicableUs
Solves - Aspirin CherryStrip81 mg/1OralPace Wellness Inc.2014-05-01Not applicableUs
Solves - Aspirin CherryStrip81 mg/1OralPace Wellness Inc.2014-05-01Not applicableUs
ST. Joseph Chewable AspirinTablet, chewable81 mg/1OralIlex Consumer Products Group, LLC2012-03-05Not applicableUs
ST. Joseph Chewable Low Dose AspirinTablet, chewable81 mg/1OralFoundation Consumer Healthcare Llc2012-03-05Not applicableUs
ST. Joseph Low Dose AspirinTablet, film coated81 mg/1OralFoundation Consumer Healthcare2014-05-30Not applicableUs
ST. Joseph Safety Coated AspirinTablet, coated81 mg/1OralBedrock Brands, LLC (ST. JOSEPH)2012-03-05Not applicableUs
Sunmark AspirinTablet, chewable81 mg/1OralMc Kesson2003-09-06Not applicableUs
Sunmark AspirinTablet, chewable81 mg/1OralMc Kesson2003-08-21Not applicableUs
Sunmark Aspirin Adult Low StrengthTablet, chewable81 mg/1OralMc Kesson2003-09-19Not applicableUs
Sunmark Aspirin Adult Low StrengthTablet, film coated81 mg/1OralMc Kesson2004-09-23Not applicableUs
Sunmark Aspirin Low DoseTablet, delayed release81 mg/1OralMc Kesson2003-08-11Not applicableUs
Sunmark Aspirin Regular StrengthTablet325 mg/1OralMc Kesson2003-06-24Not applicableUs
Topcare AspirinTablet, film coated81 mg/1OralTopco Associates LLC2005-05-03Not applicableUs
Topcare AspirinTablet, chewable81 mg/1OralTopco Associates LLC1992-08-24Not applicableUs
Topcare AspirinTablet, chewable81 mg/1OralTopco Associates LLC2006-04-28Not applicableUs
Topcare AspirinTablet, chewable81 mg/1OralTopco Associates LLC2005-03-29Not applicableUs
Tri-buffered AspirinTablet, film coated325 mg/1OralMajor Pharmaceuticals1990-03-30Not applicableUs
Uncoated AspirinTablet325 mg/1OralWOONSOCKET PRESCRIPTION CENTER,INCORPORATED1993-08-04Not applicableUs
Up and Up AspirinTablet325 mg/1OralTarget Corporation2009-06-10Not applicableUs
Up and Up AspirinTablet, chewable81 mg/1OralTarget Corporation2009-06-24Not applicableUs
Up and Up AspirinTablet, film coated81 mg/1OralTarget Corporation2009-07-22Not applicableUs
Up and Up Chewable AspirinTablet, chewable81 mg/1OralTarget Corporation2015-09-09Not applicableUs
Value Pharma Aspirin Pain RelieverTablet81 mg/81mgOralAjes Pharmaceuticals,LLC2012-10-01Not applicableUs
Value Pharmapain Reliever Extra StrengthTablet325 mg/325mgOralAjes Pharmaceuticals,LLC2012-10-01Not applicableUs
Viva Asa 325 mgTablet325 mgOralViva Pharmaceutical Inc.2006-12-192011-11-17Canada
Zee AspirinTablet325 mg/1OralZee Medical Inc2012-06-12Not applicableUs
Unapproved/Other Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
AspirinTablet81 mg/1OralCardinal Health2011-05-23Not applicableUs
AspirinTablet, chewable81 mg/1OralMc Kesson Contract Packaging2011-11-17Not applicableUs
AspirinTablet325 mg/1OralCardinal Health2011-06-02Not applicableUs
Childrens AspirinTablet, chewable81 mg/1OralCardinal Helath2011-06-02Not applicableUs
Childrens Chewable AspirinTablet, chewable81 mg/1OralCardinal Health2011-06-02Not applicableUs
Enteric AspirinTablet81 mg/1OralCardinal Health2011-06-02Not applicableUs
Micro-coated AspirinTablet325 mg/1OralMc Kesson Contract Packaging2011-09-30Not applicableUs
International Brands
NameCompany
AcenterineNot Available
AcetophenMerck
AdiroNot Available
AspergumNot Available
AsproNot Available
Bayer AspirinBayer HealthCare LLC.
EasprinNot Available
EmpirinNot Available
Nu-sealsNot Available
RhodineNot Available
RhonalNot Available
SolprinNot Available
Solprin acidNot Available
St. Joseph Aspirin for AdultsNot Available
TasprinNot Available
Brand mixtures
NameLabellerIngredients
10 Person AnsiGenuine First Aid LLC
217Merck Frosst Canada & Cie, Merck Frosst Canada & Co.
217 Strong TabMerck Frosst Canada & Cie, Merck Frosst Canada & Co.
222 TabletsMcneil Consumer Healthcare Division Of Johnson & Johnson Inc
25 Person AnsiGenuine First Aid LLC
282 Mep TabMerck Frosst Canada & Cie, Merck Frosst Canada & Co.
282 TabMerck Frosst Canada & Cie, Merck Frosst Canada & Co.
282 TabletsPendopharm Division Of De Pharmascience Inc
292 TabMerck Frosst Canada & Cie, Merck Frosst Canada & Co.
292 TabletsPendopharm Division Of De Pharmascience Inc
50 Person AnsiGenuine First Aid LLC
692 TabMerck Frosst Canada & Cie, Merck Frosst Canada & Co.
692 TabletLioh Inc.
7 Select Migraine Formula7 Eleven
A & C Tablets With Codeine 15mgD.C. Labs Limited
A & C Tablets With Codeine 30mgD.C. Labs Limited
A.C. & C 8mg TabVita Health Products Inc
A.C. & C. 8 mgLaboratoires Confab Inc
A.C. & C. 8mgWestcan Pharmaceuticals Ltd.
A.C.& C TabletsPharmascience Inc
A.S.A. With Methocarbamol Night-time Extra StrengthPharmetics (2011) Inc
Ac and C Tab 1/8grPharmascience Inc
Ac&c TabletsPharmascience Inc
Acetylsalicylic Acid, Caffeine & 8 Mg Codeine Phosphate TabletsJamp Pharma Corporation
Acetylsalicylic Acid, Caffeine and 8mg Codeine PhosphatePharmetics (2011) Inc
Ache and Pain Relief To GoBreakthrough Products Inc.
Acme First Aid Contains 404 PiecesAcme United Corp.
Adalat XL PlusBayer Inc
Added Strength Pain RelieverBetter Living Brands, Llc
Advanced Pain RelieverAdvanced First Aid, Inc.
AggrenoxRebel Distributors Corp.
Alka SeltzerSalimex, S.A.
Alka Seltzer EvtMiles Canada Inc. Consumer Health Care Division
Alka Seltzer FlavouredMiles Canada Inc. Consumer Health Care Division
Alka Seltzer OriginalNavajo Manufacturing Company Inc.
Alka Seltzer Plus ColdNavajo Manufacturing Company Inc.
Alka-seltzerLil' Drug Store Products, Inc
Alka-seltzer FlavouredBayer Inc Consumer Care
Alka-seltzer Flavoured - EvtBayer Inc Consumer Care
Alka-seltzer Lemon LimeBayer Health Care Consumer Care
Alka-seltzer Morning ReliefBayer Inc Consumer Care
Alka-seltzer OriginalR J General Corporation
Alka-seltzer PlusLil' Drug Store Products, Inc
Alka-seltzer Plus Cold and Cough FormulaBayer Health Care Consumer Care
Alka-seltzer Plus Cold Formula (cherry Burst)Bayer Health Care Consumer Care
Alka-seltzer Plus Cold Formula (orange Zest)Bayer Health Care Consumer Care
Alka-seltzer Plus Cold Medicine Sparkling OriginalBayer Health Care Consumer Care
Alka-seltzer Plus Day Non Drowsy Cold Medicine CitrusBayer Health Care Llc, Consumer Care
Alka-seltzer Plus Night Cold Formula (lemon)Bayer Health Care Consumer Care
Alka-seltzer Plus Night Cold MedicineBayer Health Care Llc, Consumer Care
Alka-seltzer Xtra StrengthBayer Health Care Llc, Consumer Care
AnacinInsight Pharmaceuticals
Anacin AFInsight Pharmaceuticals
Anacin CapletsWyeth Consumer Healthcare Inc.
Anacin EsInsight Pharmaceuticals
Anacin Extra StrengthPaladin Labs Inc
Anacin Extra Strength CapletsWyeth Consumer Healthcare Inc.
Anacin Extra Strength TabletWyeth Consumer Healthcare Inc.
Anacin TabletWyeth Consumer Healthcare Inc.
Anacin With Codeine TabWhitehall Robins Inc.
Antidol TabletsLes Produits Gerbex Inc.
Arc Emergency Preparedness First Aid Contains 202 PiecesAmerican Red Cross
Arc First Aid Contains 1000 PiecesAmerican Red Cross
Arc First Aid Contains 101 PiecesAmerican Red Cross
Arc First Aid Contains 101 Pieces HardcaseAmerican Red Cross
Arc First Aid Contains 404 PiecesAmerican Red Cross
Arco Pain TabLaboratoire Romilo
Arthriten Inflammatory Pain FormulaAlva Amco Pharmacal Companies, Inc.
Asa and CaffeineTherapharma Inc.
Asa-caffeine-codeineLaboratoires Confab Inc
Asa, Caffeine & 8mg Codeine PhosphateCanapharm Manufacturing Inc
Asasantine CapBoehringer Ingelheim (Canada) Ltd Ltee
Ascomp With CodeineNexgen Pharma, Inc.
Aspirin and DipyridamoleRoxane Laboratories, Inc.
Aspirin BackacheBayer Inc Consumer Care
Aspirin Night-timeBayer Inc Consumer Care
Aspirin Plus Stomach Guard Ext.stgth.capletSterling Winthrop Inc.
Aspirin Plus Stomach Guard Extra StrengthBayer Inc Consumer Care
Aspirin Plus Stomach Guard TabSterling Winthrop Inc.
Aspirin Rapid ReliefBayer Inc Consumer Care
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Aspirin With Stomach Guard Extra Strength - TabBayer Inc Consumer Care
Aspirin, Caffeine, and Dihydrocodeine BitartrateCaraco Pharmaceutical Laboratories, Ltd
Auto 157Genuine First Aid LLC
Axisal-C1/8Technilab Pharma Inc.
Back and Body Extra StrengthGreenbrier International, Inc.
Backaid Inflammatory Pain FormulaAlva Amco Pharmacal Companies, Inc.
Bayer Am Extra StengthBayer Health Care Llc, Consumer Care
Bayer Back and Body Extra StrengthBayer Health Care Llc, Consumer Care
Bayer Headache ReliefBayer Health Care Llc
Bayer Migraine FormulaBayer Health Care Llc, Consumer Care
Bayer PMBayer Health Care Llc, Consumer Care
Bayer WomensBayer Health Care Llc, Consumer Care
BcMedtech Products Inc.
Bc ArthritisMedtech Products Inc.
Bc CherryMedtech Products Inc.
Berkley and Jensen Migraine FormulaBJWC
Berkley and Jensen Migraine ReliefBJWC
Bi Electro Extra StrengthGenomma Lab Usa
BlowfishRally Labs Llc
Bromo SeltzerTower Laboratories Ltd
Butalbital CompoundMajor Pharmaceuticals
Butalbital, Aspirin and CaffeineWest ward Pharmaceutical Corp
Butalbital, Aspirin and Caffeine TabletsQualitest
Butalbital, Aspirin, and CaffeineLannett Company, Inc.
Butalbital, Aspirin, Caffeine and Codeine PhosphateLannett Company, Inc.
Butalbital, Aspirin, Caffeine, and Codeine PhosphateMayne Pharma Inc.
C T Acetylsalicylic Acid Codeine and Caf TabPharmavite Laboratories (1987) Inc.
C-2 Buffered With CodeinePharmascience Inc
C2 Buffered TabWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.
C2 Buffered With Codeine TabWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.
C2 Tab With CodeineWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.
Calmine TabLes Laboratoires Vachon Inc.
Care One Headache Relief Added StrengthAmerican Sales Company
Care One Migraine ReliefAmerican Sales Company
Carisoprodol and AspirinEon Labs, Inc.
Carisoprodol, Aspirin and Codeine PhosphateEon Labs, Inc.
Circle K Headache ReliefLil' Drug Store Products, Inc
CitramonBorisovskiy Zavod Medicinskikh Preparatov Jsc
Coachs First Aid Contains 102 PiecesCramer Sports
Conrx Pain RelieverEagle Distributors,Inc.
Coricidin D TabSchering Plough Canada Inc
Coricidin Nd TabSchering Plough Canada Inc
Coricidin TabSchering Plough Canada Inc
Coryphen 325 Codeine 30 TabRougier Pharma Division Of Ratiopharm Inc
Coryphen 650 Codeine 30 TabRougier Pharma Division Of Ratiopharm Inc
Darvon N Compound Pulvule 405Eli Lilly Canada Inc
Dg Health Headache Relief Added StrengthDolgencorp, LLC
Dg Health Migraine ReliefDolgencorp, LLC
Dolomine 37Frega Inc.
Dristan CapsulesWhitehall Robins Inc.
Dry Socket PasteSultan Healthcare
DuoplavinSanofi Pharma Bristol Myers Squibb Snc
Effervescent Antacid and Pain ReliefCardinal Health Inc.
Effervescent Cold ReliefCardinal Health, Inc
Effervescent Pain ReliefWestern Family Foods, Inc.
Effervescent Pain Relief Fast ReliefDeseret Laboratories, Inc.
Effervescent Pain Relief Fast Relief Fast ReliefMajor Pharmaceuticals
EndodanSTAT Rx USA LLC
Equagesic TabletsWyeth Ayerst Canada Inc.
Equaline Headache Formula Added StrengthSupervalu Inc
Equaline Migraine FormulaSupervalu Inc
Equate Migraine ReliefWal Mart Stores Inc
ExaprinHART Health
Excedrin Back and BodyNovartis Consumer Health, Inc.
Excedrin Extra StrengthNovartis Consumer Health, Inc.
Excedrin Extra Strength CapletsNovartis Consumer Health, Inc.
Excedrin Extra Strength GeltabsNovartis Consumer Health, Inc
Excedrin Extra Strength Pain RelieverNovartis Consumer Health, Inc.
Excedrin Menstrual CompleteNovartis Consumer Health, Inc.
Excedrin MigraineNovartis Consumer Health, Inc.
Excedrin Migraine GeltabsNovartis Consumer Health, Inc
Excedrin PM Triple Action CapletsNovartis Consumer Health, Inc.
Extra Pain ReliefTime Cap Labs
Extra Strenght Headache ReliefSpirit Pharmaceutical Llc
Extra Strength Aspirin BackacheBayer Inc Consumer Care
Extra Strength Back and BodyWALGREEN CO.
Extra Strength Headache ReliefTarget Corporation
Extra Strength MidolBayer Inc Consumer Care
Extra Strength Midol ReliefBayer Inc Consumer Care
Extra Strength Muscle & Back Pain Asa 500 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 500 mgVita Health Products Inc
Extra Strength Muscle & Back Pain Relief With AsaVita Health Products Inc
Extra Strength Pain RelieverRite Aid
Family Wellness Migraine ReliefFamily Dollar Services Inc
FiorinalActavis Pharma, Inc.
Fiorinal C1/2Tribute Pharmaceuticals Canada Inc
Fiorinal C1/4Tribute Pharmaceuticals Canada Inc
Fiorinal TabNovartis Pharmaceuticals Canada Inc
Fiorinal With CodeineActavis Pharma, Inc.
First Aid Contains 101 PiecesGenuine First Aid LLC
First Aid Contains 101 Pieces HardcaseGenuine First Aid LLC
First Aid Contains 303 PiecesGenuine First Aid LLC
Formu Care Pain Reliever Added StrengthAccess Business Group LLC
Genuine First Aid Emergency Preparedness Contains 167 Pieces HardcaseGenuine First Aid LLC
Gfa First Aid Kit Essentials - 33 PiecesGenuine First Aid, LLC
Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 PiecesAmerisource Bergen
Good Neighbor Pharmacy First Aid Contains 202 PiecesAmerisource Bergen
Good Neighbor Pharmacy Headache ReliefAmerisource Bergen
Good Neighbor Pharmacy Migraine ReliefAmerisource Bergen
Good Sense Headache Formula Added StrengthL Perrigo Company
Good Sense Migraine FormulaL. Perrigo Company
GoodysGlaxo Smith Kline Consumer Healthcare Lp
Goodys Back and Body PainMedtech Products Inc.
Goodys Cool OrangeLil' Drug Store Products, Inc
Goodys Cool Orange HeadacheMedtech Products Inc.
Goodys Extra StrengthMedtech Products Inc.
Goodys Extra Strength Headache Mixed Fruit BlastMedtech Products Inc.
Goodys Migraine ReliefMedtech Products Inc.
Goodys PM Pain RelieverMedtech Products Inc.
Green Guard Pain and Ache ReliefUnifirst First Aid Corporation
Handy Solutions Headache Pain ReliefNavajo Manufacturing Company Inc.
Harris Teeter Migraine ReliefHarris Teeter, LLC
Headache Formula Added StrengthKroger Company
Headache Formula Extra StrengthArmy and Air Force Exchange Service
Headache ReliefTarget Corporation
Headache Relief Added StrengthMedicine Shoppe International Inc
Headache Relief Extra StrengthWalgreens
Headache Relief PMWalgreens
Headache Relief To GoBreakthrough Products Inc.
Health Mart Migraine FormulaMc Kesson
Health Mart Migraine ReliefMc Kesson
Healthy Accents Headache Relief Added StrengthDZA Brands LLC
Healthy Accents Migraine FormulaDZA Brands LLC
Herbopyrine Tab 325mgHerbes Universelles Inc.
Instantine - TabletsBayer Inc Consumer Care
Instantine TabSterling Winthrop Inc.
K-mart Smartsense First Aid Contains 101 PiecesK Mart
Leader Headache Formula Added StrengthCardinal Health
Leader Migraine FormulaCardinal Health
Lil Drug Store Headache Relief Extra StrengthLil' Drug Store Products, Inc.
MadelonLes Laboratoires Du Saint Laurent E.H. Ltee
Medi First Pain ReliefUnifirst First Aid Corporation
Medi First Plus Pain ZapperUnifirst First Aid Corporation
Medique Medi SeltzerUnifirst First Aid Corporation
Medique Pain OffUnifirst First Aid Corporation
MethoxisalRougier Pharma Division Of Ratiopharm Inc
Methoxisal Extra StrengthTeva Canada Limited
Methoxisal-C 1/2Teva Canada Limited
Methoxisal-C 1/4Teva Canada Limited
Methoxisal-C 1/8Teva Canada Limited
Midol RegularBayer Inc Consumer Care
Migraine FormulaSafeway
Migraine ReliefWalgreen Company
Migralex Dr. MauskopMigralex Inc.
Mountain Series Weekender MedicalTender Corporation Dba Adventure Medical Kits
Muscle & Back Pain Asa 325 Mg Methocarbamol 400 Mg & Acetylsalicylic Acid 325 mgVita Health Products Inc
Muscle & Back Pain Relief Extra StrengthPendopharm Division Of De Pharmascience Inc
Muscle and Back Pain ReliefPendopharm Division Of De Pharmascience Inc
Muscle and Back Pain Relief Extra StrengthPendopharm Division Of De Pharmascience Inc
Muscle and Back Pain Relief With AsaTechnilab Pharma Inc.
Muscle and Back Pain Relief With Asa Extra StrengthTechnilab Pharma Inc.
Muscle Relaxant and AnalgesicTechnilab Pharma Inc.
Muscle Relaxant and Back Pain Relief Extra Strength TabletsPharmetics (2011) Inc
Muscle Relaxant and Back Pain Relief Regular Strength TabletsPharmetics (2011) Inc
NervineJ L Mathieu Cie Ltee
Nervine TabJ L Mathieu Cie Ltee
Neutra-seltzerTeva Canada Limited
Nezger TabLes Produits Gerbex Inc.
Norgesic3 M Pharmaceuticals
Norgesic Forte3 M Pharmaceuticals
Norgesic Forte Tab3 M Pharmaceuticals, A Division Of 3 M Canada Company
Norgesic Tab3 M Pharmaceuticals, A Division Of 3 M Canada Company
Novo Ac and C 8mg TabNovopharm Limited
Novo-propoxyn Compound CapNovopharm Limited
Orphenadrine Citrate, Aspirin and CaffeineRebel Distributors Corp
Oxycodone and AspirinPhysicians Total Care, Inc.
Oxycodone Hydrochloride and AspirinMylan Pharmaceuticals Inc.
Pain AidZee Medical Inc
Pain Aid EsfZee Medical Inc
Pain Away PlusMedex Merchandising Llc
Pain FreeAfassco Inc.
Pain Free PlusAfassco Inc.
Pain Relief Added StrengthBetter Living Brands, Llc
Pain Relief Extra StrengthL&R Distributors, Inc.
Pain Relief Fast ReliefSelect Brand
Pain Relief Maximum StrengthSelect Corporation
Pain Relief PMCVS Pharmacy
Pain RelieverAdvanced First Aid, Inc.
Pain Reliever Added StrengthTarget Corporation
Pain Reliever Extra StrengthCostco Wholesale Corporation
Pain Reliever PlusClinical Solutions Wholesale
Pain Stopper ExtraNorth Safety Products LLC
Pain Stoppers ExtraNorth Safety Products LLC
Pain Stoppers RegularNorth Safety Products LLC
Pain TerminatorProvision Medical Products
Pain Terminator 2 SevereProvision Medical Products
Painex Tab 0.25grIcn Canada Ltd.
Painex Tab 0.5grIcn Canada Ltd.
Pal-pravastatin-asaPaladin Labs Inc
Pamprin Max Menstrual Pain ReliefChattem, Inc.
PercodanEndo Pharmaceuticals Inc
Percodan-demiBristol Myers Squibb Canada
Phenaphen No 2 CapAyerst Laboratories
Phenaphen No 3 CapAyerst Laboratories
Phenaphen No 4 CapAyerst Laboratories
Phenaphen No.2 CapWyeth Ayerst Canada Inc.
Phenaphen No.3 CapWyeth Ayerst Canada Inc.
Phenaphen No.4 CapWyeth Ayerst Canada Inc.
Picot Plus EffervescentBristol Myers Squibb De Mexico, S. De R.L. De C.V.
PMS-pharnal CapsulesPharmascience Inc
PMS-pharnal TabletsPharmascience Inc
PMS-pharnal-C 1/4 CapsulesPharmascience Inc
PMS-pharnal-C1/2 CapsulesPharmascience Inc
Premier Value Antacid and Pain Relief MedicineChain Drug Consortium, LLC
Pronal - C1/2 CapsulesPro Doc Limitee
Pronal C1/4 CapsulesPro Doc Limitee
Pronal CapsulesPro Doc Limitee
Pronal TabletsPro Doc Limitee
ProtectionGenuine First Aid LLC
Quality Choice Effervescent Cold Relief PlusChain Drug Marketing Association
Ratio-oxycodanTeva Canada Limited
Ratio-tecnalTeva Canada Limited
Ratio-tecnal C 1/2Teva Canada Limited
Ratio-tecnal C 1/4Teva Canada Limited
Ready America First Aid Outdoor- 107 PiecesGenuine First Aid, LLC
Ready America First Aid Pocket - 33 PiecesGenuine First Aid, LLC
Regular Strength AspirinWALGREEN CO.
RivacodanLaboratoire Riva Inc
Robaxisal C 1/2Pfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Robaxisal C 1/4Pfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Robaxisal C-1/8 TabletsWyeth Consumer Healthcare Inc.
Robaxisal CapletsWyeth Consumer Healthcare Inc.
Robaxisal Extra StrengthPfizer Consumer Healthcare A Division Of Pfizer Canada Inc
Robaxisal TabletsWyeth Consumer Healthcare Inc.
Rx Act Headache Formula Added StrengthH E B
Shoprite Migraine FormulaWakefern Food Corporation
Signature Care Migraine ReliefSafeway
Smart Sense Migraine FormulaKmart Corporation
Smart Sense Migraine ReliefKmart Corporation
Sohmed Pain RelieverSOHM Inc.
Spasmhalt-asa-8Pendopharm Division Of De Pharmascience Inc
StanbackMedtech Products Inc.
Sunmark Headache ReliefMc Kesson
Sunmark Migraine ReliefMc Kesson
Super Extra Strength Aspirin BackacheBayer Inc Consumer Care
SynalgosCaraco Pharma Inc.
Tabcin 500Salimex, S.A.
Thrulife Extra Strength Headache ReliefPolygen Pharmaceuticals LLC
Topcare Headache FormulaTopco Associates LLC
Topcare Migraine FormulaTopco Associates LLC
Tri-buffered Asa TabZee Medical Inc
Trianal C½Laboratoire Riva Inc
Trianal C¼Laboratoire Riva Inc
Trianal CapsulesLaboratoire Riva Inc
Trianal TabletLaboratoire Riva Inc
Up and Up Migraine ReliefTarget Corporation
Uricalm IntensiveAlva Amco Pharmacal Companies, Inc.
VanquishMOBERG PHARMA NORTH AMERICA LLC
Vida Mia Pain ReliefNavarro Discount Pharmacies, LLC
Winco Foods Effervescent Antacid and Pain ReliefWin Co Foods, Llc
Winco Foods Effervescent Cold ReliefWin Co Foods, Llc
YospralaAralez Pharmaceuticals Us Inc.
Zee Pain AidZee Medical Inc
Zee-seltzer Antacid and Pain RelieverZEE MEDICAL
SaltsNot Available
Categories
UNIIR16CO5Y76E
CAS number50-78-2
WeightAverage: 180.1574
Monoisotopic: 180.042258744
Chemical FormulaC9H8O4
InChI KeyBSYNRYMUTXBXSQ-UHFFFAOYSA-N
InChI
InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
IUPAC Name
2-(acetyloxy)benzoic acid
SMILES
CC(=O)OC1=CC=CC=C1C(O)=O
Pharmacology
IndicationFor use in the temporary relief of various forms of pain, inflammation associated with various conditions (including rheumatoid arthritis, juvenile rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, and ankylosing spondylitis), and is also used to reduce the risk of death and/or nonfatal myocardial infarction in patients with a previous infarction or unstable angina pectoris.
Structured Indications
PharmacodynamicsAcetylsalicylic acid is an analgesic, antipyretic, antirheumatic, and anti-inflammatory agent. Acetylsalicylic acid's mode of action as an antiinflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. Acetylsalicylic acid appears to produce analgesia by virtue of both a peripheral and CNS effect. Peripherally, acetylsalicylic acid acts by inhibiting the synthesis and release of prostaglandins. Acting centrally, it would appear to produce analgesia at a hypothalamic site in the brain, although the mode of action is not known. Acetylsalicylic acid also acts on the hypothalamus to produce antipyresis; heat dissipation is increased as a result of vasodilation and increased peripheral blood flow. Acetylsalicylic acid's antipyretic activity may also be related to inhibition of synthesis and release of prostaglandins.
Mechanism of actionThe analgesic, antipyretic, and anti-inflammatory effects of acetylsalicylic acid are due to actions by both the acetyl and the salicylate portions of the intact molecule as well as by the active salicylate metabolite. Acetylsalicylic acid directly and irreversibly inhibits the activity of both types of cyclooxygenase (COX-1 and COX-2) to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid. This makes acetylsalicylic acid different from other NSAIDS (such as diclofenac and ibuprofen) which are reversible inhibitors. Salicylate may competitively inhibit prostaglandin formation. Acetylsalicylic acid's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms; the therapeutic effects are not due to pituitary-adrenal stimulation. The platelet aggregation-inhibiting effect of acetylsalicylic acid specifically involves the compound's ability to act as an acetyl donor to cyclooxygenase; the nonacetylated salicylates have no clinically significant effect on platelet aggregation. Irreversible acetylation renders cyclooxygenase inactive, thereby preventing the formation of the aggregating agent thromboxane A2 in platelets. Since platelets lack the ability to synthesize new proteins, the effects persist for the life of the exposed platelets (7-10 days). Acetylsalicylic acid may also inhibit production of the platelet aggregation inhibitor, prostacyclin (prostaglandin I2), by blood vessel endothelial cells; however, inhibition prostacyclin production is not permanent as endothelial cells can produce more cyclooxygenase to replace the non-functional enzyme.
TargetKindPharmacological actionActionsOrganismUniProt ID
Prostaglandin G/H synthase 1Proteinyes
inhibitor
HumanP23219 details
Prostaglandin G/H synthase 2Proteinyes
inhibitor
HumanP35354 details
Aldo-keto reductase family 1 member C1Proteinunknown
inhibitor
HumanQ04828 details
5'-AMP-activated protein kinase catalytic subunit alpha-1Proteinunknown
activator
HumanQ13131 details
Endothelin-1 receptorProteinunknownNot AvailableHumanP25101 details
Inhibitor of nuclear factor kappa-B kinase subunit betaProteinunknownNot AvailableHumanO14920 details
Cellular tumor antigen p53Proteinunknown
acetylation
HumanP04637 details
78 kDa glucose-regulated proteinProteinunknown
binding
HumanP11021 details
Ribosomal protein S6 kinase alpha-3ProteinunknownNot AvailableHumanP51812 details
NF-kappa-B inhibitor alphaProteinunknownNot AvailableHumanP25963 details
Nuclear factor NF-kappa-B p100 subunitProteinunknown
antagonist
HumanQ00653 details
Related Articles
AbsorptionAbsorption is generally rapid and complete following oral administration but may vary according to specific salicylate used, dosage form, and other factors such as tablet dissolution rate and gastric or intraluminal pH.
Volume of distributionNot Available
Protein bindingHigh (99.5%) to albumin. Decreases as plasma salicylate concentration increases, with reduced plasma albumin concentration or renal dysfunction, and during pregnancy.
Metabolism

Acetylsalicylic acid is rapidly hydrolyzed primarily in the liver to salicylic acid, which is conjugated with glycine (forming salicyluric acid) and glucuronic acid and excreted largely in the urine.

SubstrateEnzymesProduct
Acetylsalicylic acid
Not Available
1-Salicylate glucuronideDetails
Route of eliminationNot Available
Half lifeThe plasma half-life is approximately 15 minutes; that for salicylate lengthens as the dose increases: doses of 300 to 650 mg have a half-life of 3.1 to 3.2 hours; with doses of 1 gram, the half-life is increased to 5 hours and with 2 grams it is increased to about 9 hours.
ClearanceNot Available
ToxicityOral, mouse: LD50 = 250 mg/kg; Oral, rabbit: LD50 = 1010 mg/kg; Oral, rat: LD50 = 200 mg/kg. Effects of overdose include: tinnitus, abdominal pain, hypokalemia, hypoglycemia, pyrexia, hyperventilation, dysrhythmia, hypotension, hallucination, renal failure, confusion, seizure, coma, and death.
Affected organisms
  • Humans and other mammals
Pathways
PathwayCategorySMPDB ID
Acetylsalicylic Acid Action PathwayDrug actionSMP00083
SNP Mediated Effects
Interacting Gene/EnzymeSNP RS IDAllele nameDefining changeEffectReference(s)
Cytochrome P450 2C9
Gene symbol: CYP2C9
UniProt: P11712
rs1057910 CYP2C9*1C AllelePoor drug metabolizer, lower dose requirements12893985
Integrin beta-3
Gene symbol: ITGB3
UniProt: P05106
rs5918 Not AvailableT > CPatients are more resistant to the anti-thrombotic effects of aspirin11723016
SNP Mediated Adverse Drug Reactions
Interacting Gene/EnzymeSNP RS IDAllele nameDefining changeAdverse ReactionReference(s)
Leukotriene C4 synthase
Gene symbol: LTC4S
UniProt: Q16873
rs730012 Not AvailableC alleleAspirin-induced urticaria16433794
Interactions
Drug Interactions
DrugInteractionDrug group
16-BromoepiandrosteroneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with 16-Bromoepiandrosterone.Investigational
19-norandrostenedioneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with 19-norandrostenedione.Experimental, Illicit
4-AndrostenedioneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with 4-Androstenedione.Experimental, Illicit
5-androstenedioneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with 5-androstenedione.Experimental, Illicit
AbciximabThe risk or severity of adverse effects can be increased when Abciximab is combined with Acetylsalicylic acid.Approved
AbirateroneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Abiraterone.Approved
AcarboseAcetylsalicylic acid may increase the hypoglycemic activities of Acarbose.Approved, Investigational
AcebutololAcetylsalicylic acid may decrease the antihypertensive activities of Acebutolol.Approved
AceclofenacThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Aceclofenac.Approved
AcenocoumarolAcetylsalicylic acid may increase the anticoagulant activities of Acenocoumarol.Approved
AcetaminophenThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Acetaminophen.Approved
AcetazolamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Acetazolamide.Approved, Vet Approved
AcetovanilloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Acetovanillone.Investigational
AclarubicinAcetylsalicylic acid may decrease the excretion rate of Aclarubicin which could result in a higher serum level.Investigational
AdapaleneThe risk or severity of adverse effects can be increased when Adapalene is combined with Acetylsalicylic acid.Approved
AfatinibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Afatinib.Approved
AlbendazoleThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Albendazole.Approved, Vet Approved
AlbiglutideAcetylsalicylic acid may increase the hypoglycemic activities of Albiglutide.Approved
AlclometasoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Alclometasone.Approved
AldosteroneThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Aldosterone.Experimental
AlectinibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Alectinib.Approved
Alendronic acidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Alendronic acid.Approved
AlfentanilThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Alfentanil.Approved, Illicit
AliskirenAcetylsalicylic acid may decrease the antihypertensive activities of Aliskiren.Approved, Investigational
AlogliptinAcetylsalicylic acid may increase the hypoglycemic activities of Alogliptin.Approved
AlprenololAcetylsalicylic acid may decrease the antihypertensive activities of Alprenolol.Approved, Withdrawn
AlprostadilThe risk or severity of adverse effects can be increased when Alprostadil is combined with Acetylsalicylic acid.Approved, Investigational
AlteplaseThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Alteplase.Approved
ALX-0081The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with ALX-0081.Investigational
AmantadineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Amantadine.Approved
AmcinonideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Amcinonide.Approved
AmikacinAcetylsalicylic acid may decrease the excretion rate of Amikacin which could result in a higher serum level.Approved, Vet Approved
AmilorideAcetylsalicylic acid may decrease the antihypertensive activities of Amiloride.Approved
Aminohippuric acidThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Aminohippuric acid.Approved
Aminosalicylic AcidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Aminosalicylic Acid.Approved
AmiodaroneThe metabolism of Acetylsalicylic acid can be decreased when combined with Amiodarone.Approved, Investigational
AmitriptylineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Amitriptyline.Approved
AmlodipineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Amlodipine.Approved
Ammonium chlorideThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ammonium chloride.Approved, Vet Approved
AmprenavirThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Amprenavir.Approved
AmrubicinAcetylsalicylic acid may decrease the excretion rate of Amrubicin which could result in a higher serum level.Approved, Investigational
AmsacrineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Amsacrine.Approved
AnagrelideThe risk or severity of adverse effects can be increased when Anagrelide is combined with Acetylsalicylic acid.Approved
AncrodAcetylsalicylic acid may increase the anticoagulant activities of Ancrod.Investigational
AnecortaveThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Anecortave.Investigational
AnisodamineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Anisodamine.Investigational
AnistreplaseThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Anistreplase.Approved
annamycinAcetylsalicylic acid may decrease the excretion rate of annamycin which could result in a higher serum level.Investigational
AntipyrineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Antipyrine.Approved
Antithrombin III humanAcetylsalicylic acid may increase the anticoagulant activities of Antithrombin III human.Approved
Aop200704Acetylsalicylic acid may decrease the antihypertensive activities of Aop200704.Investigational
ApixabanThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Apixaban.Approved
ApramycinAcetylsalicylic acid may decrease the excretion rate of Apramycin which could result in a higher serum level.Experimental, Vet Approved
ApremilastThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Apremilast.Approved, Investigational
AprepitantThe metabolism of Acetylsalicylic acid can be increased when combined with Aprepitant.Approved, Investigational
AprotininThe therapeutic efficacy of Acetylsalicylic acid can be decreased when used in combination with Aprotinin.Approved, Withdrawn
ArbekacinAcetylsalicylic acid may decrease the excretion rate of Arbekacin which could result in a higher serum level.Approved
ArdeparinAcetylsalicylic acid may increase the anticoagulant activities of Ardeparin.Approved, Withdrawn
ArgatrobanThe risk or severity of adverse effects can be increased when Argatroban is combined with Acetylsalicylic acid.Approved, Investigational
ArotinololAcetylsalicylic acid may decrease the antihypertensive activities of Arotinolol.Approved
AstaxanthinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Astaxanthin.Investigational
AstemizoleThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Astemizole.Approved, Withdrawn
AtazanavirThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Atazanavir.Approved, Investigational
AtenololThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Atenolol.Approved
AtorvastatinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Atorvastatin.Approved
AzapropazoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Azapropazone.Withdrawn
AzelastineThe risk or severity of adverse effects can be increased when Azelastine is combined with Acetylsalicylic acid.Approved
Azilsartan medoxomilThe risk or severity of adverse effects can be increased when Azilsartan medoxomil is combined with Acetylsalicylic acid.Approved
AzithromycinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Azithromycin.Approved
BalsalazideAcetylsalicylic acid may increase the nephrotoxic activities of Balsalazide.Approved, Investigational
BatroxobinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Batroxobin.Experimental
BecaplerminAcetylsalicylic acid may increase the anticoagulant activities of Becaplermin.Approved, Investigational
BeclomethasoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Beclomethasone.Investigational
Beclomethasone dipropionateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Beclomethasone dipropionate.Approved, Investigational
BefunololAcetylsalicylic acid may decrease the antihypertensive activities of Befunolol.Experimental
BemiparinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Bemiparin.Approved
BenazeprilAcetylsalicylic acid may decrease the antihypertensive activities of Benazepril.Approved, Investigational
BendroflumethiazideThe therapeutic efficacy of Bendroflumethiazide can be decreased when used in combination with Acetylsalicylic acid.Approved
BenoxaprofenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Benoxaprofen.Withdrawn
BenzocaineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Benzocaine.Approved
BepridilThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Bepridil.Approved, Withdrawn
BeraprostThe risk or severity of adverse effects can be increased when Beraprost is combined with Acetylsalicylic acid.Investigational
BetamethasoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Betamethasone.Approved, Vet Approved
BetaxololAcetylsalicylic acid may decrease the antihypertensive activities of Betaxolol.Approved
Betulinic AcidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Betulinic Acid.Investigational
BevantololAcetylsalicylic acid may decrease the antihypertensive activities of Bevantolol.Approved
BimatoprostThe therapeutic efficacy of Bimatoprost can be decreased when used in combination with Acetylsalicylic acid.Approved, Investigational
BiperidenThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Biperiden.Approved
BisoprololAcetylsalicylic acid may decrease the antihypertensive activities of Bisoprolol.Approved
BivalirudinAcetylsalicylic acid may increase the anticoagulant activities of Bivalirudin.Approved, Investigational
BopindololAcetylsalicylic acid may decrease the antihypertensive activities of Bopindolol.Approved
BosutinibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Bosutinib.Approved
BrinzolamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Brinzolamide.Approved
BromfenacThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Bromfenac.Approved
BromocriptineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Bromocriptine.Approved, Investigational
BucillamineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Bucillamine.Investigational
BucindololAcetylsalicylic acid may decrease the antihypertensive activities of Bucindolol.Investigational
BudesonideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Budesonide.Approved
BufuralolAcetylsalicylic acid may decrease the antihypertensive activities of Bufuralol.Experimental, Investigational
BumetanideAcetylsalicylic acid may decrease the diuretic activities of Bumetanide.Approved
BupranololAcetylsalicylic acid may decrease the antihypertensive activities of Bupranolol.Approved
BuprenorphineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Buprenorphine.Approved, Illicit, Investigational, Vet Approved
BuspironeThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Buspirone.Approved, Investigational
ButylphthalideThe risk or severity of adverse effects can be increased when Butylphthalide is combined with Acetylsalicylic acid.Investigational
CabazitaxelThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Cabazitaxel.Approved
CaffeineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Caffeine.Approved
CanagliflozinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Canagliflozin.Approved
CandesartanThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Candesartan.Approved
CandoxatrilAcetylsalicylic acid may decrease the antihypertensive activities of Candoxatril.Experimental
CangrelorThe risk or severity of adverse effects can be increased when Cangrelor is combined with Acetylsalicylic acid.Approved
CapecitabineThe metabolism of Acetylsalicylic acid can be decreased when combined with Capecitabine.Approved, Investigational
CaptoprilThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Captopril.Approved
CarbamazepineThe metabolism of Acetylsalicylic acid can be increased when combined with Carbamazepine.Approved, Investigational
Carboprost TromethamineThe therapeutic efficacy of Carboprost Tromethamine can be decreased when used in combination with Acetylsalicylic acid.Approved
CarisoprodolThe serum concentration of the active metabolites of Carisoprodol can be increased when Carisoprodol is used in combination with Acetylsalicylic acid.Approved
CarprofenThe risk or severity of adverse effects can be increased when Carprofen is combined with Acetylsalicylic acid.Approved, Vet Approved, Withdrawn
CarteololAcetylsalicylic acid may decrease the antihypertensive activities of Carteolol.Approved
CarvedilolThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Carvedilol.Approved, Investigational
CaspofunginThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Caspofungin.Approved
CastanospermineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Castanospermine.Experimental
CelecoxibThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Celecoxib.Approved, Investigational
CeliprololAcetylsalicylic acid may decrease the antihypertensive activities of Celiprolol.Approved, Investigational
CeritinibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ceritinib.Approved
CertoparinAcetylsalicylic acid may increase the anticoagulant activities of Certoparin.Approved
ChloroquineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Chloroquine.Approved, Vet Approved
ChlorothiazideThe therapeutic efficacy of Chlorothiazide can be decreased when used in combination with Acetylsalicylic acid.Approved, Vet Approved
ChlorpromazineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Chlorpromazine.Approved, Vet Approved
ChlorpropamideThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Chlorpropamide.Approved
ChlorprothixeneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Chlorprothixene.Approved, Withdrawn
ChlorthalidoneThe therapeutic efficacy of Chlorthalidone can be decreased when used in combination with Acetylsalicylic acid.Approved
CholecalciferolThe metabolism of Acetylsalicylic acid can be decreased when combined with Cholecalciferol.Approved, Nutraceutical
CholesterolThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Cholesterol.Experimental
CholestyramineCholestyramine can cause a decrease in the absorption of Acetylsalicylic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Cholic AcidThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Cholic Acid.Approved
CiclesonideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ciclesonide.Approved, Investigational
CilazaprilThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Cilazapril.Approved
CilostazolThe risk or severity of adverse effects can be increased when Cilostazol is combined with Acetylsalicylic acid.Approved
CimetidineThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Cimetidine.Approved
CinoxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Cinoxacin.Approved, Withdrawn
CiprofloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Ciprofloxacin.Approved, Investigational
CitalopramCitalopram may increase the antiplatelet activities of Acetylsalicylic acid.Approved
Citric AcidAcetylsalicylic acid may increase the anticoagulant activities of Citric Acid.Nutraceutical, Vet Approved
ClarithromycinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Clarithromycin.Approved
ClobetasolThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Clobetasol.Investigational
Clobetasol propionateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Clobetasol propionate.Approved
ClocortoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Clocortolone.Approved
ClodronateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Clodronate.Approved, Investigational, Vet Approved
ClofazimineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Clofazimine.Approved, Investigational
ClomipramineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Clomipramine.Approved, Vet Approved
ClonixinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Clonixin.Approved
ClopidogrelThe metabolism of Acetylsalicylic acid can be decreased when combined with Clopidogrel.Approved, Nutraceutical
CloprostenolThe therapeutic efficacy of Cloprostenol can be decreased when used in combination with Acetylsalicylic acid.Vet Approved
ClotrimazoleThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Clotrimazole.Approved, Vet Approved
CobicistatThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Cobicistat.Approved
ColchicineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Colchicine.Approved
ColesevelamColesevelam can cause a decrease in the absorption of Acetylsalicylic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
ColestipolColestipol can cause a decrease in the absorption of Acetylsalicylic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
ColforsinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Colforsin.Experimental
CollagenaseThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Collagenase.Approved
Cortisone acetateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Cortisone acetate.Approved
CrizotinibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Crizotinib.Approved
CurcuminThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Curcumin.Investigational
CyclophosphamideThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Cyclophosphamide.Approved, Investigational
CyclosporineAcetylsalicylic acid may increase the nephrotoxic activities of Cyclosporine.Approved, Investigational, Vet Approved
CyclosporineThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Cyclosporine.Approved, Investigational, Vet Approved
D-LimoneneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with D-Limonene.Investigational
Dabigatran etexilateAcetylsalicylic acid may increase the anticoagulant activities of Dabigatran etexilate.Approved
DabrafenibThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Dabrafenib.Approved
DaclatasvirThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Daclatasvir.Approved
DactinomycinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Dactinomycin.Approved
DalteparinAcetylsalicylic acid may increase the anticoagulant activities of Dalteparin.Approved
DanaparoidAcetylsalicylic acid may increase the anticoagulant activities of Danaparoid.Approved, Withdrawn
DapagliflozinAcetylsalicylic acid may increase the hypoglycemic activities of Dapagliflozin.Approved
DapoxetineDapoxetine may increase the antiplatelet activities of Acetylsalicylic acid.Investigational
DasatinibDasatinib may increase the anticoagulant activities of Acetylsalicylic acid.Approved, Investigational
DaunorubicinAcetylsalicylic acid may decrease the excretion rate of Daunorubicin which could result in a higher serum level.Approved
DeferasiroxThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Deferasirox.Approved, Investigational
DefibrotideThe risk or severity of adverse effects can be increased when Defibrotide is combined with Acetylsalicylic acid.Approved, Investigational
dehydroepiandrosterone sulfateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with dehydroepiandrosterone sulfate.Investigational
DelavirdineThe metabolism of Acetylsalicylic acid can be decreased when combined with Delavirdine.Approved
Deoxycholic AcidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Deoxycholic Acid.Approved
dersalazineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with dersalazine.Investigational
DesipramineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Desipramine.Approved
DesirudinAcetylsalicylic acid may increase the anticoagulant activities of Desirudin.Approved
DesloratadineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Desloratadine.Approved, Investigational
DesmopressinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Desmopressin.Approved
DesmoteplaseThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Desmoteplase.Investigational
DesoximetasoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Desoximetasone.Approved
Desoxycorticosterone acetateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Desoxycorticosterone acetate.Approved
Desoxycorticosterone PivalateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Desoxycorticosterone Pivalate.Experimental, Vet Approved
DesvenlafaxineDesvenlafaxine may increase the antiplatelet activities of Acetylsalicylic acid.Approved
DexamethasoneThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Dexamethasone.Approved, Investigational, Vet Approved
Dexamethasone isonicotinateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Dexamethasone isonicotinate.Vet Approved
DexketoprofenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Dexketoprofen.Approved
DextranAcetylsalicylic acid may increase the anticoagulant activities of Dextran.Approved, Vet Approved
Dextran 40Acetylsalicylic acid may increase the anticoagulant activities of Dextran 40.Approved
Dextran 70Acetylsalicylic acid may increase the anticoagulant activities of Dextran 70.Approved
Dextran 75Acetylsalicylic acid may increase the anticoagulant activities of Dextran 75.Approved
DextromethorphanThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Dextromethorphan.Approved
DiclofenacThe risk or severity of adverse effects can be increased when Diclofenac is combined with Acetylsalicylic acid.Approved, Vet Approved
DiclofenacThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Diclofenac.Approved, Vet Approved
DiclofenamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Diclofenamide.Approved
DicoumarolAcetylsalicylic acid may increase the anticoagulant activities of Dicoumarol.Approved
DiflorasoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Diflorasone.Approved
DiflunisalThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Diflunisal.Approved
DifluocortoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Difluocortolone.Approved
DifluprednateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Difluprednate.Approved
DigoxinThe serum concentration of Digoxin can be increased when it is combined with Acetylsalicylic acid.Approved
DihydroergotamineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Dihydroergotamine.Approved
DihydrostreptomycinAcetylsalicylic acid may decrease the excretion rate of Dihydrostreptomycin which could result in a higher serum level.Vet Approved
DiltiazemThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Diltiazem.Approved
DinoprostThe therapeutic efficacy of Dinoprost can be decreased when used in combination with Acetylsalicylic acid.Investigational
Dinoprost TromethamineThe therapeutic efficacy of Dinoprost Tromethamine can be decreased when used in combination with Acetylsalicylic acid.Approved, Vet Approved
DinoprostoneThe therapeutic efficacy of Dinoprostone can be decreased when used in combination with Acetylsalicylic acid.Approved
DipyridamoleThe risk or severity of adverse effects can be increased when Dipyridamole is combined with Acetylsalicylic acid.Approved
DisopyramideAcetylsalicylic acid may increase the hypoglycemic activities of Disopyramide.Approved
DitazoleThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ditazole.Approved, Withdrawn
DorzolamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Dorzolamide.Approved
DoxazosinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Doxazosin.Approved
DoxepinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Doxepin.Approved
DoxorubicinAcetylsalicylic acid may decrease the excretion rate of Doxorubicin which could result in a higher serum level.Approved, Investigational
DronabinolThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Dronabinol.Approved, Illicit
DronedaroneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Dronedarone.Approved
DrospirenoneAcetylsalicylic acid may increase the hyperkalemic activities of Drospirenone.Approved
Drotrecogin alfaThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Drotrecogin alfa.Approved, Investigational, Withdrawn
DroxicamThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Droxicam.Approved
DulaglutideAcetylsalicylic acid may increase the hypoglycemic activities of Dulaglutide.Approved
DuloxetineDuloxetine may increase the antiplatelet activities of Acetylsalicylic acid.Approved
DuvelisibThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Duvelisib.Investigational
E6201The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with E6201.Investigational
EbselenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ebselen.Investigational
Edetic AcidAcetylsalicylic acid may increase the anticoagulant activities of Edetic Acid.Approved, Vet Approved
EdoxabanAcetylsalicylic acid may increase the anticoagulant activities of Edoxaban.Approved
EfavirenzThe metabolism of Acetylsalicylic acid can be decreased when combined with Efavirenz.Approved, Investigational
ElbasvirThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Elbasvir.Approved
EmpagliflozinAcetylsalicylic acid may increase the hypoglycemic activities of Empagliflozin.Approved
EnalaprilThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Enalapril.Approved, Vet Approved
EnalaprilatAcetylsalicylic acid may decrease the antihypertensive activities of Enalaprilat.Approved
EnoxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Enoxacin.Approved
EnoxaparinAcetylsalicylic acid may increase the anticoagulant activities of Enoxaparin.Approved
EnzalutamideThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Enzalutamide.Approved
EpinastineThe risk or severity of adverse effects can be increased when Epinastine is combined with Acetylsalicylic acid.Approved, Investigational
EpirizoleThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Epirizole.Approved
EpirubicinAcetylsalicylic acid may decrease the excretion rate of Epirubicin which could result in a higher serum level.Approved
EplerenoneAcetylsalicylic acid may decrease the antihypertensive activities of Eplerenone.Approved
eplivanserineThe risk or severity of adverse effects can be increased when eplivanserine is combined with Acetylsalicylic acid.Investigational
EpoprostenolThe risk or severity of adverse effects can be increased when Epoprostenol is combined with Acetylsalicylic acid.Approved
EprosartanThe risk or severity of adverse effects can be increased when Eprosartan is combined with Acetylsalicylic acid.Approved
EptifibatideThe risk or severity of adverse effects can be increased when Eptifibatide is combined with Acetylsalicylic acid.Approved, Investigational
EquileninThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Equilenin.Experimental
EquilinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Equilin.Approved
ErgonovineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ergonovine.Approved
ErgotamineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ergotamine.Approved
ErythromycinThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Erythromycin.Approved, Vet Approved
EscitalopramEscitalopram may increase the antiplatelet activities of Acetylsalicylic acid.Approved, Investigational
EsmololAcetylsalicylic acid may decrease the antihypertensive activities of Esmolol.Approved
EstramustineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Estramustine.Approved
EstriolThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Estriol.Approved, Vet Approved
EstroneThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Estrone.Approved
Estrone sulfateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Estrone sulfate.Approved
Etacrynic acidAcetylsalicylic acid may decrease the diuretic activities of Etacrynic acid.Approved
EtanerceptThe risk or severity of adverse effects can be increased when Etanercept is combined with Acetylsalicylic acid.Approved, Investigational
EthanolThe risk or severity of adverse effects can be increased when Ethanol is combined with Acetylsalicylic acid.Approved
EthoxzolamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ethoxzolamide.Withdrawn
Ethyl biscoumacetateAcetylsalicylic acid may increase the anticoagulant activities of Ethyl biscoumacetate.Withdrawn
Etidronic acidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Etidronic acid.Approved
EtodolacThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Etodolac.Approved, Investigational, Vet Approved
EtofenamateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Etofenamate.Approved
EtoperidoneEtoperidone may increase the antiplatelet activities of Acetylsalicylic acid.Approved
EtoposideThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Etoposide.Approved
EtoricoxibThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Etoricoxib.Approved, Investigational
EtravirineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Etravirine.Approved
Evening primrose oilThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Evening primrose oil.Approved
ExenatideAcetylsalicylic acid may increase the hypoglycemic activities of Exenatide.Approved, Investigational
exisulindThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with exisulind.Investigational
FelodipineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Felodipine.Approved, Investigational
FenbufenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fenbufen.Approved
FenoprofenThe risk or severity of adverse effects can be increased when Fenoprofen is combined with Acetylsalicylic acid.Approved
FenprostaleneThe therapeutic efficacy of Fenprostalene can be decreased when used in combination with Acetylsalicylic acid.Vet Approved
FentanylThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Fentanyl.Approved, Illicit, Investigational, Vet Approved
FexofenadineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Fexofenadine.Approved
FibrinolysinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fibrinolysin.Approved
FidaxomicinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Fidaxomicin.Approved
FleroxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Fleroxacin.Approved
FloctafenineThe risk or severity of adverse effects can be increased when Floctafenine is combined with Acetylsalicylic acid.Approved, Withdrawn
FloxuridineThe metabolism of Acetylsalicylic acid can be decreased when combined with Floxuridine.Approved
fluasteroneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with fluasterone.Investigational
FluconazoleThe metabolism of Acetylsalicylic acid can be decreased when combined with Fluconazole.Approved
FludrocortisoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fludrocortisone.Approved
FluindioneAcetylsalicylic acid may increase the anticoagulant activities of Fluindione.Investigational
FlumequineAcetylsalicylic acid may increase the neuroexcitatory activities of Flumequine.Withdrawn
FlumethasoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Flumethasone.Approved, Vet Approved
FlunisolideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Flunisolide.Approved, Investigational
FlunixinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Flunixin.Vet Approved
Fluocinolone AcetonideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fluocinolone Acetonide.Approved, Investigational, Vet Approved
FluocinonideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fluocinonide.Approved, Investigational
FluocortoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fluocortolone.Approved, Withdrawn
FluorometholoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fluorometholone.Approved
FluorouracilThe metabolism of Acetylsalicylic acid can be decreased when combined with Fluorouracil.Approved
FluoxetineFluoxetine may increase the antiplatelet activities of Acetylsalicylic acid.Approved, Vet Approved
FlupentixolThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Flupentixol.Approved, Withdrawn
FluphenazineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Fluphenazine.Approved
FluprednideneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fluprednidene.Approved, Withdrawn
FluprednisoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fluprednisolone.Approved
FluprostenolThe therapeutic efficacy of Fluprostenol can be decreased when used in combination with Acetylsalicylic acid.Vet Approved
FlurandrenolideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Flurandrenolide.Approved
FlurazepamThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Flurazepam.Approved, Illicit
FlurbiprofenThe risk or severity of adverse effects can be increased when Flurbiprofen is combined with Acetylsalicylic acid.Approved, Investigational
Fluticasone furoateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fluticasone furoate.Approved
Fluticasone PropionateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Fluticasone Propionate.Approved
FluvastatinThe metabolism of Acetylsalicylic acid can be decreased when combined with Fluvastatin.Approved
FluvoxamineFluvoxamine may increase the antiplatelet activities of Acetylsalicylic acid.Approved, Investigational
Folic AcidThe therapeutic efficacy of Folic Acid can be decreased when used in combination with Acetylsalicylic acid.Approved, Nutraceutical, Vet Approved
FondaparinuxAcetylsalicylic acid may increase the anticoagulant activities of Fondaparinux.Investigational
Fondaparinux sodiumAcetylsalicylic acid may increase the anticoagulant activities of Fondaparinux sodium.Approved, Investigational
ForasartanThe risk or severity of adverse effects can be increased when Forasartan is combined with Acetylsalicylic acid.Experimental
FormestaneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Formestane.Approved, Investigational, Withdrawn
FosinoprilAcetylsalicylic acid may decrease the antihypertensive activities of Fosinopril.Approved
FosphenytoinThe metabolism of Acetylsalicylic acid can be increased when combined with Fosphenytoin.Approved
FramycetinAcetylsalicylic acid may decrease the excretion rate of Framycetin which could result in a higher serum level.Approved
FurosemideAcetylsalicylic acid may decrease the diuretic activities of Furosemide.Approved, Vet Approved
GabexateAcetylsalicylic acid may increase the anticoagulant activities of Gabexate.Investigational
GarenoxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Garenoxacin.Investigational
GatifloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Gatifloxacin.Approved, Investigational
GefitinibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Gefitinib.Approved, Investigational
GemeprostThe therapeutic efficacy of Gemeprost can be decreased when used in combination with Acetylsalicylic acid.Approved, Withdrawn
GemfibrozilThe metabolism of Acetylsalicylic acid can be decreased when combined with Gemfibrozil.Approved
GemifloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Gemifloxacin.Approved, Investigational
GeneticinAcetylsalicylic acid may decrease the excretion rate of Geneticin which could result in a higher serum level.Experimental
GenisteinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Genistein.Investigational
GentamicinAcetylsalicylic acid may decrease the excretion rate of Gentamicin which could result in a higher serum level.Approved, Vet Approved
GENTAMICIN C1AAcetylsalicylic acid may decrease the excretion rate of GENTAMICIN C1A which could result in a higher serum level.Experimental
Ginkgo bilobaGinkgo biloba may increase the anticoagulant activities of Acetylsalicylic acid.Approved, Nutraceutical
GliclazideAcetylsalicylic acid may increase the hypoglycemic activities of Gliclazide.Approved
GlimepirideAcetylsalicylic acid may increase the hypoglycemic activities of Glimepiride.Approved
GlipizideAcetylsalicylic acid may increase the hypoglycemic activities of Glipizide.Approved
GlucosamineGlucosamine may increase the antiplatelet activities of Acetylsalicylic acid.Approved
GlyburideThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Glyburide.Approved
GlycerolThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Glycerol.Experimental
Gramicidin DThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Gramicidin D.Approved
GrepafloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Grepafloxacin.Withdrawn
HaloperidolThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Haloperidol.Approved
HE3286The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with HE3286.Investigational
HeparinAcetylsalicylic acid may increase the anticoagulant activities of Heparin.Approved, Investigational
HigenamineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Higenamine.Investigational
HirulogAcetylsalicylic acid may increase the anticoagulant activities of Hirulog.Experimental
HMPL-004The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with HMPL-004.Investigational
HyaluronidaseThe therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Acetylsalicylic acid.Approved, Investigational
HydralazineAcetylsalicylic acid may decrease the antihypertensive activities of Hydralazine.Approved
HydrochlorothiazideThe therapeutic efficacy of Hydrochlorothiazide can be decreased when used in combination with Acetylsalicylic acid.Approved, Vet Approved
HydrocortisoneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Hydrocortisone.Approved, Vet Approved
HydroflumethiazideThe therapeutic efficacy of Hydroflumethiazide can be decreased when used in combination with Acetylsalicylic acid.Approved
Hygromycin BAcetylsalicylic acid may decrease the excretion rate of Hygromycin B which could result in a higher serum level.Vet Approved
IbandronateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ibandronate.Approved, Investigational
Ibritumomab tiuxetanThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ibritumomab tiuxetan.Approved
IbrutinibThe risk or severity of adverse effects can be increased when Ibrutinib is combined with Acetylsalicylic acid.Approved
IbudilastThe risk or severity of adverse effects can be increased when Ibudilast is combined with Acetylsalicylic acid.Approved, Investigational
IbuprofenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ibuprofen.Approved
IbuproxamThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ibuproxam.Withdrawn
IcatibantThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Icatibant.Approved
Icosapent ethylThe risk or severity of adverse effects can be increased when Icosapent ethyl is combined with Acetylsalicylic acid.Approved, Nutraceutical
IdarubicinAcetylsalicylic acid may decrease the excretion rate of Idarubicin which could result in a higher serum level.Approved
IdelalisibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Idelalisib.Approved
idraparinuxAcetylsalicylic acid may increase the anticoagulant activities of idraparinux.Investigational
IfenprodilThe risk or severity of adverse effects can be increased when Ifenprodil is combined with Acetylsalicylic acid.Approved, Withdrawn
IloprostThe risk or severity of adverse effects can be increased when Iloprost is combined with Acetylsalicylic acid.Approved, Investigational
ImatinibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Imatinib.Approved
ImidaprilAcetylsalicylic acid may decrease the antihypertensive activities of Imidapril.Investigational
ImipramineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Imipramine.Approved
IndalpineIndalpine may increase the antiplatelet activities of Acetylsalicylic acid.Investigational, Withdrawn
IndapamideThe therapeutic efficacy of Indapamide can be decreased when used in combination with Acetylsalicylic acid.Approved
IndenololAcetylsalicylic acid may decrease the antihypertensive activities of Indenolol.Withdrawn
IndinavirThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Indinavir.Approved
IndobufenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Indobufen.Investigational
IndomethacinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Indomethacin.Approved, Investigational
IndoprofenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Indoprofen.Withdrawn
INNO-206Acetylsalicylic acid may decrease the excretion rate of INNO-206 which could result in a higher serum level.Investigational
Insulin AspartAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Aspart.Approved
Insulin DetemirAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Detemir.Approved
Insulin GlargineAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Glargine.Approved
Insulin GlulisineAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Glulisine.Approved
Insulin HumanAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Human.Approved, Investigational
Insulin LisproAcetylsalicylic acid may increase the hypoglycemic activities of Insulin Lispro.Approved
IrbesartanThe metabolism of Acetylsalicylic acid can be decreased when combined with Irbesartan.Approved, Investigational
IsavuconazoniumThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Isavuconazonium.Approved, Investigational
IsoxicamThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Isoxicam.Withdrawn
IstaroximeThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Istaroxime.Investigational
ItraconazoleThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Itraconazole.Approved, Investigational
IvacaftorThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ivacaftor.Approved
IvermectinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ivermectin.Approved, Vet Approved
KanamycinAcetylsalicylic acid may decrease the excretion rate of Kanamycin which could result in a higher serum level.Approved, Vet Approved
Kct 0809The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Kct 0809.Investigational
KebuzoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Kebuzone.Experimental
KetamineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ketamine.Approved, Vet Approved
KetanserinThe risk or severity of adverse effects can be increased when Ketanserin is combined with Acetylsalicylic acid.Investigational
KetoconazoleThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ketoconazole.Approved, Investigational
KetoprofenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Ketoprofen.Approved, Vet Approved
KetorolacThe risk or severity of adverse effects can be increased when Ketorolac is combined with Acetylsalicylic acid.Approved
LabetalolAcetylsalicylic acid may decrease the antihypertensive activities of Labetalol.Approved
LanreotideAcetylsalicylic acid may increase the hypoglycemic activities of Lanreotide.Approved
LansoprazoleThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Lansoprazole.Approved, Investigational
LapatinibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Lapatinib.Approved, Investigational
LatanoprostThe therapeutic efficacy of Latanoprost can be decreased when used in combination with Acetylsalicylic acid.Approved, Investigational
LeflunomideThe metabolism of Acetylsalicylic acid can be decreased when combined with Leflunomide.Approved, Investigational
LepirudinAcetylsalicylic acid may increase the anticoagulant activities of Lepirudin.Approved
LevobunololAcetylsalicylic acid may decrease the antihypertensive activities of Levobunolol.Approved
LevofloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Levofloxacin.Approved, Investigational
LevomilnacipranLevomilnacipran may increase the antiplatelet activities of Acetylsalicylic acid.Approved
LevothyroxineThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Levothyroxine.Approved
LidocaineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Lidocaine.Approved, Vet Approved
LimaprostThe risk or severity of adverse effects can be increased when Limaprost is combined with Acetylsalicylic acid.Approved
LiothyronineThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Liothyronine.Approved, Vet Approved
LiotrixThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Liotrix.Approved
LiraglutideAcetylsalicylic acid may increase the hypoglycemic activities of Liraglutide.Approved
LisinoprilThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Lisinopril.Approved, Investigational
LisofyllineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Lisofylline.Investigational
LithiumThe serum concentration of Lithium can be increased when it is combined with Acetylsalicylic acid.Approved
LomefloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Lomefloxacin.Approved
LomitapideThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Lomitapide.Approved
LoperamideThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Loperamide.Approved
LopinavirThe metabolism of Acetylsalicylic acid can be decreased when combined with Lopinavir.Approved
LoratadineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Loratadine.Approved
LornoxicamThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Lornoxicam.Approved
LosartanThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Losartan.Approved
LovastatinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Lovastatin.Approved, Investigational
LoxoprofenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Loxoprofen.Approved
LubiprostoneThe therapeutic efficacy of Lubiprostone can be decreased when used in combination with Acetylsalicylic acid.Approved, Investigational
LumacaftorThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Lumacaftor.Approved
LumiracoxibThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Lumiracoxib.Approved, Investigational
LuprostiolThe therapeutic efficacy of Luprostiol can be decreased when used in combination with Acetylsalicylic acid.Vet Approved
Magnesium salicylateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Magnesium salicylate.Approved
MaprotilineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Maprotiline.Approved
MasoprocolThe risk or severity of adverse effects can be increased when Masoprocol is combined with Acetylsalicylic acid.Approved
ME-609The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with ME-609.Investigational
MebendazoleThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Mebendazole.Approved, Vet Approved
MecaserminAcetylsalicylic acid may increase the hypoglycemic activities of Mecasermin.Approved, Investigational
Meclofenamic acidThe risk or severity of adverse effects can be increased when Meclofenamic acid is combined with Acetylsalicylic acid.Approved, Vet Approved
MedrysoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Medrysone.Approved
Mefenamic acidThe risk or severity of adverse effects can be increased when Mefenamic acid is combined with Acetylsalicylic acid.Approved
MefloquineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Mefloquine.Approved
Megestrol acetateThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Megestrol acetate.Approved, Vet Approved
MelengestrolThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Melengestrol.Vet Approved
MeloxicamThe risk or severity of adverse effects can be increased when Meloxicam is combined with Acetylsalicylic acid.Approved, Vet Approved
MeprobamateThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Meprobamate.Approved, Illicit
MesalazineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Mesalazine.Approved
MetamizoleThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Metamizole.Withdrawn
MetforminAcetylsalicylic acid may increase the hypoglycemic activities of Metformin.Approved
MethadoneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Methadone.Approved
MethazolamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Methazolamide.Approved
MethotrexateThe serum concentration of Methotrexate can be increased when it is combined with Acetylsalicylic acid.Approved
MethyclothiazideThe therapeutic efficacy of Methyclothiazide can be decreased when used in combination with Acetylsalicylic acid.Approved
MethylprednisoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Methylprednisolone.Approved, Vet Approved
MetipranololAcetylsalicylic acid may decrease the antihypertensive activities of Metipranolol.Approved
MetolazoneThe therapeutic efficacy of Metolazone can be decreased when used in combination with Acetylsalicylic acid.Approved
MetoprololThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Metoprolol.Approved, Investigational
MetrizamideAcetylsalicylic acid may decrease the excretion rate of Metrizamide which could result in a higher serum level.Approved
MibefradilThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Mibefradil.Withdrawn
MiconazoleThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Miconazole.Approved, Investigational, Vet Approved
MidazolamThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Midazolam.Approved, Illicit
MifepristoneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Mifepristone.Approved, Investigational
MiglitolAcetylsalicylic acid may increase the hypoglycemic activities of Miglitol.Approved
MilnacipranMilnacipran may increase the antiplatelet activities of Acetylsalicylic acid.Approved
MilrinoneThe risk or severity of adverse effects can be increased when Milrinone is combined with Acetylsalicylic acid.Approved
MisoprostolThe therapeutic efficacy of Misoprostol can be decreased when used in combination with Acetylsalicylic acid.Approved
MitomycinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Mitomycin.Approved
MitoxantroneThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Mitoxantrone.Approved, Investigational
MizoribineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Mizoribine.Investigational
MoexiprilAcetylsalicylic acid may decrease the antihypertensive activities of Moexipril.Approved
MometasoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Mometasone.Approved, Vet Approved
MorniflumateThe risk or severity of adverse effects can be increased when Morniflumate is combined with Acetylsalicylic acid.Approved
MorphineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Morphine.Approved, Investigational
MoxifloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Moxifloxacin.Approved, Investigational
Mycophenolate mofetilThe risk or severity of adverse effects can be increased when Mycophenolate mofetil is combined with Acetylsalicylic acid.Approved, Investigational
Mycophenolic acidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Mycophenolic acid.Approved
NabumetoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Nabumetone.Approved
NadololAcetylsalicylic acid may decrease the antihypertensive activities of Nadolol.Approved
NadroparinAcetylsalicylic acid may increase the anticoagulant activities of Nadroparin.Approved
NafamostatAcetylsalicylic acid may increase the anticoagulant activities of Nafamostat.Investigational
NaftifineThe risk or severity of adverse effects can be increased when Naftifine is combined with Acetylsalicylic acid.Approved
NaftopidilThe risk or severity of adverse effects can be increased when Naftopidil is combined with Acetylsalicylic acid.Investigational
Nalidixic AcidAcetylsalicylic acid may increase the neuroexcitatory activities of Nalidixic Acid.Approved
NaltrexoneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Naltrexone.Approved, Investigational, Vet Approved
NaproxenThe risk or severity of adverse effects can be increased when Naproxen is combined with Acetylsalicylic acid.Approved, Vet Approved
NaringeninThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Naringenin.Experimental
NateglinideAcetylsalicylic acid may increase the hypoglycemic activities of Nateglinide.Approved, Investigational
NCX 1022The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with NCX 1022.Investigational
NCX 4016The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with NCX 4016.Investigational
NeamineAcetylsalicylic acid may decrease the excretion rate of Neamine which could result in a higher serum level.Experimental
NefazodoneNefazodone may increase the antiplatelet activities of Acetylsalicylic acid.Approved, Withdrawn
NelfinavirThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Nelfinavir.Approved
NemonoxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Nemonoxacin.Investigational
NeomycinAcetylsalicylic acid may decrease the excretion rate of Neomycin which could result in a higher serum level.Approved, Vet Approved
NeostigmineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Neostigmine.Approved, Vet Approved
NepafenacThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Nepafenac.Approved
NetilmicinAcetylsalicylic acid may decrease the excretion rate of Netilmicin which could result in a higher serum level.Approved
NicardipineThe metabolism of Acetylsalicylic acid can be decreased when combined with Nicardipine.Approved
NicorandilThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Nicorandil.Approved
NifedipineThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Nifedipine.Approved
Niflumic AcidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Niflumic Acid.Approved
NilotinibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Nilotinib.Approved, Investigational
NimesulideThe risk or severity of adverse effects can be increased when Nimesulide is combined with Acetylsalicylic acid.Approved, Withdrawn
NisoldipineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Nisoldipine.Approved
NitrazepamThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Nitrazepam.Approved
NitrendipineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Nitrendipine.Approved
NitroaspirinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Nitroaspirin.Investigational
NorethisteroneThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Norethisterone.Approved
NorfloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Norfloxacin.Approved
ObinutuzumabThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Obinutuzumab.Approved
OctreotideAcetylsalicylic acid may increase the hypoglycemic activities of Octreotide.Approved, Investigational
OfloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Ofloxacin.Approved
Oleoyl estroneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Oleoyl estrone.Investigational
OlmesartanThe risk or severity of adverse effects can be increased when Olmesartan is combined with Acetylsalicylic acid.Approved, Investigational
OlopatadineThe risk or severity of adverse effects can be increased when Olopatadine is combined with Acetylsalicylic acid.Approved
OlsalazineAcetylsalicylic acid may increase the nephrotoxic activities of Olsalazine.Approved
Omacetaxine mepesuccinateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Omacetaxine mepesuccinate.Approved
OmapatrilatAcetylsalicylic acid may decrease the antihypertensive activities of Omapatrilat.Investigational
Omega-3 fatty acidsOmega-3 fatty acids may increase the antiplatelet activities of Acetylsalicylic acid.Approved
OmeprazoleThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Omeprazole.Approved, Investigational, Vet Approved
OrgoteinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Orgotein.Vet Approved
OtamixabanAcetylsalicylic acid may increase the anticoagulant activities of Otamixaban.Investigational
OxaprozinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Oxaprozin.Approved
OxprenololAcetylsalicylic acid may decrease the antihypertensive activities of Oxprenolol.Approved
OxyphenbutazoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Oxyphenbutazone.Withdrawn
P-NitrophenolThe serum concentration of Acetylsalicylic acid can be increased when it is combined with P-Nitrophenol.Experimental
PaclitaxelThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Paclitaxel.Approved, Vet Approved
Palmitic AcidThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Palmitic Acid.Experimental
PamidronateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Pamidronate.Approved
PantoprazoleThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Pantoprazole.Approved
ParamethasoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Paramethasone.Approved
ParecoxibThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Parecoxib.Approved
ParnaparinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Parnaparin.Approved
ParomomycinAcetylsalicylic acid may decrease the excretion rate of Paromomycin which could result in a higher serum level.Approved, Investigational
ParoxetineParoxetine may increase the antiplatelet activities of Acetylsalicylic acid.Approved, Investigational
PasireotideAcetylsalicylic acid may increase the hypoglycemic activities of Pasireotide.Approved
PazufloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Pazufloxacin.Investigational
PefloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Pefloxacin.Approved
PenbutololAcetylsalicylic acid may decrease the antihypertensive activities of Penbutolol.Approved, Investigational
PentamidineAcetylsalicylic acid may increase the hypoglycemic activities of Pentamidine.Approved
Pentosan PolysulfateThe risk or severity of adverse effects can be increased when Pentosan Polysulfate is combined with Acetylsalicylic acid.Approved
PentoxifyllinePentoxifylline may increase the antiplatelet activities of Acetylsalicylic acid.Approved, Investigational
PerindoprilThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Perindopril.Approved
PhenindioneAcetylsalicylic acid may increase the anticoagulant activities of Phenindione.Approved
PhenobarbitalThe metabolism of Acetylsalicylic acid can be increased when combined with Phenobarbital.Approved
PhenprocoumonAcetylsalicylic acid may increase the anticoagulant activities of Phenprocoumon.Approved
PhenylbutazoneThe risk or severity of adverse effects can be increased when Phenylbutazone is combined with Acetylsalicylic acid.Approved, Vet Approved
PhenytoinThe metabolism of Acetylsalicylic acid can be increased when combined with Phenytoin.Approved, Vet Approved
PimecrolimusThe risk or severity of adverse effects can be increased when Pimecrolimus is combined with Acetylsalicylic acid.Approved, Investigational
PimozideThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Pimozide.Approved
PindololAcetylsalicylic acid may decrease the antihypertensive activities of Pindolol.Approved
PioglitazoneThe metabolism of Acetylsalicylic acid can be decreased when combined with Pioglitazone.Approved, Investigational
PirarubicinAcetylsalicylic acid may decrease the excretion rate of Pirarubicin which could result in a higher serum level.Investigational
PiretanideAcetylsalicylic acid may decrease the diuretic activities of Piretanide.Experimental
PirfenidoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Pirfenidone.Investigational
PiroxicamThe risk or severity of adverse effects can be increased when Piroxicam is combined with Acetylsalicylic acid.Approved, Investigational
PlasminThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Plasmin.Investigational
Platelet Activating FactorThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Platelet Activating Factor.Experimental
PlicamycinAcetylsalicylic acid may decrease the excretion rate of Plicamycin which could result in a higher serum level.Approved, Withdrawn
PolythiazideThe therapeutic efficacy of Polythiazide can be decreased when used in combination with Acetylsalicylic acid.Approved
PonatinibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ponatinib.Approved
PosaconazoleThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Posaconazole.Approved, Investigational, Vet Approved
PractololAcetylsalicylic acid may decrease the antihypertensive activities of Practolol.Approved
PralatrexateThe serum concentration of Pralatrexate can be increased when it is combined with Acetylsalicylic acid.Approved
PramlintideAcetylsalicylic acid may increase the hypoglycemic activities of Pramlintide.Approved, Investigational
PrasteroneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Prasterone.Approved, Nutraceutical
PrasugrelThe risk or severity of adverse effects can be increased when Prasugrel is combined with Acetylsalicylic acid.Approved
PravastatinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Pravastatin.Approved
PrazosinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Prazosin.Approved
PrednicarbateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Prednicarbate.Approved
PrednisoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Prednisolone.Approved, Vet Approved
PrednisoneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Prednisone.Approved, Vet Approved
PregnenoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Pregnenolone.Experimental
PrimidoneThe metabolism of Acetylsalicylic acid can be increased when combined with Primidone.Approved, Vet Approved
ProbenecidThe therapeutic efficacy of Probenecid can be decreased when used in combination with Acetylsalicylic acid.Approved
ProgesteroneThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Progesterone.Approved, Vet Approved
PromethazineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Promethazine.Approved
PropacetamolThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Propacetamol.Approved
PropafenoneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Propafenone.Approved
PropranololThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Propranolol.Approved, Investigational
Prostaglandin B2The therapeutic efficacy of Prostaglandin B2 can be decreased when used in combination with Acetylsalicylic acid.Experimental
Prostaglandin D2The therapeutic efficacy of Prostaglandin D2 can be decreased when used in combination with Acetylsalicylic acid.Experimental, Investigational
Prostaglandin G2The therapeutic efficacy of Prostaglandin G2 can be decreased when used in combination with Acetylsalicylic acid.Experimental
ProstaleneThe therapeutic efficacy of Prostalene can be decreased when used in combination with Acetylsalicylic acid.Vet Approved
Protein CAcetylsalicylic acid may increase the anticoagulant activities of Protein C.Approved
Protein S humanAcetylsalicylic acid may increase the anticoagulant activities of Protein S human.Approved
ProtocatechualdehydeAcetylsalicylic acid may increase the anticoagulant activities of Protocatechualdehyde.Approved
ProtriptylineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Protriptyline.Approved
PrulifloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Prulifloxacin.Investigational
PTC299The risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with PTC299.Investigational
PuromycinAcetylsalicylic acid may decrease the excretion rate of Puromycin which could result in a higher serum level.Experimental
PyrimethamineThe metabolism of Acetylsalicylic acid can be decreased when combined with Pyrimethamine.Approved, Vet Approved
QuercetinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Quercetin.Experimental
QuinacrineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Quinacrine.Approved
QuinaprilAcetylsalicylic acid may decrease the antihypertensive activities of Quinapril.Approved, Investigational
QuinethazoneThe therapeutic efficacy of Quinethazone can be decreased when used in combination with Acetylsalicylic acid.Approved
QuinidineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Quinidine.Approved
QuinineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Quinine.Approved
RabeprazoleThe metabolism of Acetylsalicylic acid can be decreased when combined with Rabeprazole.Approved, Investigational
RamatrobanThe risk or severity of adverse effects can be increased when Ramatroban is combined with Acetylsalicylic acid.Investigational
RamiprilAcetylsalicylic acid may decrease the antihypertensive activities of Ramipril.Approved
RanitidineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ranitidine.Approved
RanolazineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Ranolazine.Approved, Investigational
ReboxetineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Reboxetine.Approved, Investigational
RegorafenibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Regorafenib.Approved
RepaglinideAcetylsalicylic acid may increase the hypoglycemic activities of Repaglinide.Approved, Investigational
RescinnamineAcetylsalicylic acid may decrease the antihypertensive activities of Rescinnamine.Approved
ReserpineThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Reserpine.Approved
ResveratrolThe risk or severity of adverse effects can be increased when Resveratrol is combined with Acetylsalicylic acid.Experimental, Investigational
ReteplaseThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Reteplase.Approved
ReviparinAcetylsalicylic acid may increase the anticoagulant activities of Reviparin.Approved
RibostamycinAcetylsalicylic acid may decrease the excretion rate of Ribostamycin which could result in a higher serum level.Approved
RidogrelThe risk or severity of adverse effects can be increased when Ridogrel is combined with Acetylsalicylic acid.Approved
RifampicinThe metabolism of Acetylsalicylic acid can be increased when combined with Rifampicin.Approved
RifapentineThe metabolism of Acetylsalicylic acid can be increased when combined with Rifapentine.Approved
RilpivirineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Rilpivirine.Approved
RimexoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Rimexolone.Approved
RisedronateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Risedronate.Approved, Investigational
RitonavirThe metabolism of Acetylsalicylic acid can be decreased when combined with Ritonavir.Approved, Investigational
RivaroxabanAcetylsalicylic acid may increase the anticoagulant activities of Rivaroxaban.Approved
RofecoxibThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Rofecoxib.Investigational, Withdrawn
RolapitantThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Rolapitant.Approved
RosiglitazoneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Rosiglitazone.Approved, Investigational
RosoxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Rosoxacin.Approved
SacubitrilThe risk or severity of adverse effects can be increased when Sacubitril is combined with Acetylsalicylic acid.Approved
SalicylamideThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Salicylamide.Approved
Salicylic acidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Salicylic acid.Approved, Vet Approved
SalsalateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Salsalate.Approved
SaprisartanThe risk or severity of adverse effects can be increased when Saprisartan is combined with Acetylsalicylic acid.Experimental
SaquinavirThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Saquinavir.Approved, Investigational
SaralasinThe risk or severity of adverse effects can be increased when Saralasin is combined with Acetylsalicylic acid.Investigational
SaxagliptinAcetylsalicylic acid may increase the hypoglycemic activities of Saxagliptin.Approved
SCH-530348The risk or severity of adverse effects can be increased when SCH-530348 is combined with Acetylsalicylic acid.Investigational
ScopolamineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Scopolamine.Approved
SecobarbitalThe metabolism of Acetylsalicylic acid can be increased when combined with Secobarbital.Approved, Vet Approved
SelegilineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Selegiline.Approved, Investigational, Vet Approved
SelexipagThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Selexipag.Approved
SeratrodastThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Seratrodast.Approved, Investigational
SertralineSertraline may increase the antiplatelet activities of Acetylsalicylic acid.Approved
SevofluraneThe risk or severity of adverse effects can be increased when Sevoflurane is combined with Acetylsalicylic acid.Approved, Vet Approved
SildenafilThe metabolism of Acetylsalicylic acid can be decreased when combined with Sildenafil.Approved, Investigational
SimeprevirThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Simeprevir.Approved
SimvastatinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Simvastatin.Approved
SirolimusThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Sirolimus.Approved, Investigational
SisomicinAcetylsalicylic acid may decrease the excretion rate of Sisomicin which could result in a higher serum level.Investigational
SitagliptinAcetylsalicylic acid may increase the hypoglycemic activities of Sitagliptin.Approved, Investigational
SorafenibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Sorafenib.Approved, Investigational
SotalolAcetylsalicylic acid may decrease the antihypertensive activities of Sotalol.Approved
SP1049CAcetylsalicylic acid may decrease the excretion rate of SP1049C which could result in a higher serum level.Investigational
SparfloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Sparfloxacin.Approved
SpectinomycinAcetylsalicylic acid may decrease the excretion rate of Spectinomycin which could result in a higher serum level.Approved, Vet Approved
SpiraprilAcetylsalicylic acid may decrease the antihypertensive activities of Spirapril.Approved
SpironolactoneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Spironolactone.Approved
SRT501The risk or severity of adverse effects can be increased when SRT501 is combined with Acetylsalicylic acid.Investigational
St. John's WortThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with St. John's Wort.Nutraceutical
StaurosporineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Staurosporine.Experimental
StiripentolThe metabolism of Acetylsalicylic acid can be decreased when combined with Stiripentol.Approved
StreptokinaseThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Streptokinase.Approved
StreptomycinAcetylsalicylic acid may decrease the excretion rate of Streptomycin which could result in a higher serum level.Approved, Vet Approved
StreptozocinAcetylsalicylic acid may decrease the excretion rate of Streptozocin which could result in a higher serum level.Approved
SulfadiazineThe metabolism of Acetylsalicylic acid can be decreased when combined with Sulfadiazine.Approved, Vet Approved
SulfamethoxazoleThe metabolism of Acetylsalicylic acid can be decreased when combined with Sulfamethoxazole.Approved
SulfasalazineAcetylsalicylic acid may increase the nephrotoxic activities of Sulfasalazine.Approved
SulfinpyrazoneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Sulfinpyrazone.Approved
SulfisoxazoleThe metabolism of Acetylsalicylic acid can be decreased when combined with Sulfisoxazole.Approved, Vet Approved
SulindacThe risk or severity of adverse effects can be increased when Sulindac is combined with Acetylsalicylic acid.Approved
SulodexideAcetylsalicylic acid may increase the anticoagulant activities of Sulodexide.Approved, Investigational
SulprostoneThe therapeutic efficacy of Sulprostone can be decreased when used in combination with Acetylsalicylic acid.Investigational
SumatriptanThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Sumatriptan.Approved, Investigational
SunitinibThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Sunitinib.Approved, Investigational
SuprofenThe risk or severity of adverse effects can be increased when Suprofen is combined with Acetylsalicylic acid.Approved, Withdrawn
TacrineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Tacrine.Withdrawn
TacrolimusThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Tacrolimus.Approved, Investigational
TacrolimusAcetylsalicylic acid may increase the nephrotoxic activities of Tacrolimus.Approved, Investigational
TafluprostThe therapeutic efficacy of Tafluprost can be decreased when used in combination with Acetylsalicylic acid.Approved
TalniflumateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Talniflumate.Approved
TamoxifenThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Tamoxifen.Approved
TasosartanThe risk or severity of adverse effects can be increased when Tasosartan is combined with Acetylsalicylic acid.Approved
Taurocholic AcidThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Taurocholic Acid.Experimental
Technetium tc 99m etidronateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Technetium tc 99m etidronate.Approved
Technetium Tc-99m MedronateThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Technetium Tc-99m Medronate.Approved
TelmisartanThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Telmisartan.Approved, Investigational
TemafloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Temafloxacin.Withdrawn
TemocaprilAcetylsalicylic acid may decrease the antihypertensive activities of Temocapril.Experimental, Investigational
TemsirolimusThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Temsirolimus.Approved
TenecteplaseThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Tenecteplase.Approved
TenofovirThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Tenofovir.Approved, Investigational
TenoxicamThe risk or severity of adverse effects can be increased when Tenoxicam is combined with Acetylsalicylic acid.Approved
TepoxalinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Tepoxalin.Vet Approved
TerazosinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Terazosin.Approved
TerfenadineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Terfenadine.Withdrawn
TeriflunomideThe metabolism of Acetylsalicylic acid can be decreased when combined with Teriflunomide.Approved
TesmilifeneThe risk or severity of adverse effects can be increased when Tesmilifene is combined with Acetylsalicylic acid.Investigational
TestosteroneThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Testosterone.Approved, Investigational
Tiaprofenic acidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Tiaprofenic acid.Approved
TicagrelorAcetylsalicylic acid may increase the antiplatelet activities of Ticagrelor.Approved
TiclopidineThe risk or severity of adverse effects can be increased when Ticlopidine is combined with Acetylsalicylic acid.Approved
TiludronateThe serum concentration of Tiludronate can be decreased when it is combined with Acetylsalicylic acid.Approved, Vet Approved
TimololAcetylsalicylic acid may decrease the antihypertensive activities of Timolol.Approved
TinoridineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Tinoridine.Investigational
TinzaparinThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Tinzaparin.Approved
TipranavirTipranavir may increase the antiplatelet activities of Acetylsalicylic acid.Approved, Investigational
TirofibanThe risk or severity of adverse effects can be increased when Tirofiban is combined with Acetylsalicylic acid.Approved
TixocortolThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Tixocortol.Approved
TobramycinAcetylsalicylic acid may decrease the excretion rate of Tobramycin which could result in a higher serum level.Approved, Investigational
TolazamideAcetylsalicylic acid may increase the hypoglycemic activities of Tolazamide.Approved
TolbutamideThe metabolism of Acetylsalicylic acid can be decreased when combined with Tolbutamide.Approved
Tolfenamic AcidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Tolfenamic Acid.Approved
TolmetinThe risk or severity of adverse effects can be increased when Tolmetin is combined with Acetylsalicylic acid.Approved
TolvaptanThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Tolvaptan.Approved
TorasemideAcetylsalicylic acid may decrease the diuretic activities of Torasemide.Approved
TositumomabThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Tositumomab.Approved
TrandolaprilAcetylsalicylic acid may decrease the antihypertensive activities of Trandolapril.Approved
TranilastThe risk or severity of adverse effects can be increased when Tranilast is combined with Acetylsalicylic acid.Approved, Investigational
TrapidilThe risk or severity of adverse effects can be increased when Trapidil is combined with Acetylsalicylic acid.Approved
TravoprostThe therapeutic efficacy of Travoprost can be decreased when used in combination with Acetylsalicylic acid.Approved
TrazodoneThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Trazodone.Approved, Investigational
TreprostinilThe risk or severity of adverse effects can be increased when Treprostinil is combined with Acetylsalicylic acid.Approved, Investigational
TriamcinoloneThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Triamcinolone.Approved, Vet Approved
TriamtereneAcetylsalicylic acid may decrease the antihypertensive activities of Triamterene.Approved
TrichlormethiazideThe therapeutic efficacy of Trichlormethiazide can be decreased when used in combination with Acetylsalicylic acid.Approved, Vet Approved
TrifluoperazineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Trifluoperazine.Approved
TriflupromazineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Triflupromazine.Approved, Vet Approved
TriflusalThe risk or severity of adverse effects can be increased when Triflusal is combined with Acetylsalicylic acid.Approved
TrimethoprimThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Trimethoprim.Approved, Vet Approved
TrimipramineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Trimipramine.Approved
Trisalicylate-cholineThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Trisalicylate-choline.Approved
TroleandomycinThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Troleandomycin.Approved
TrovafloxacinAcetylsalicylic acid may increase the neuroexcitatory activities of Trovafloxacin.Approved, Withdrawn
UnoprostoneThe therapeutic efficacy of Unoprostone can be decreased when used in combination with Acetylsalicylic acid.Approved
UrokinaseAcetylsalicylic acid may increase the anticoagulant activities of Urokinase.Approved, Investigational, Withdrawn
ValdecoxibThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Valdecoxib.Investigational, Withdrawn
Valproic AcidThe serum concentration of Valproic Acid can be increased when it is combined with Acetylsalicylic acid.Approved, Investigational
ValrubicinAcetylsalicylic acid may decrease the excretion rate of Valrubicin which could result in a higher serum level.Approved
ValsartanThe metabolism of Acetylsalicylic acid can be decreased when combined with Valsartan.Approved, Investigational
VancomycinThe serum concentration of Vancomycin can be increased when it is combined with Acetylsalicylic acid.Approved
VenlafaxineVenlafaxine may increase the antiplatelet activities of Acetylsalicylic acid.Approved
VerapamilThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Verapamil.Approved
VinblastineThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Vinblastine.Approved
VincristineThe serum concentration of Acetylsalicylic acid can be decreased when it is combined with Vincristine.Approved, Investigational
VinorelbineThe serum concentration of Acetylsalicylic acid can be increased when it is combined with Vinorelbine.Approved, Investigational
Vitamin EVitamin E may increase the antiplatelet activities of Acetylsalicylic acid.Approved, Nutraceutical, Vet Approved
VorapaxarThe risk or severity of adverse effects can be increased when Vorapaxar is combined with Acetylsalicylic acid.Approved
VoriconazoleThe metabolism of Acetylsalicylic acid can be decreased when combined with Voriconazole.Approved, Investigational
WarfarinAcetylsalicylic acid may increase the anticoagulant activities of Warfarin.Approved
XimelagatranAcetylsalicylic acid may increase the anticoagulant activities of Ximelagatran.Approved, Investigational, Withdrawn
Ym150Acetylsalicylic acid may increase the anticoagulant activities of Ym150.Investigational
ZafirlukastThe metabolism of Acetylsalicylic acid can be decreased when combined with Zafirlukast.Approved, Investigational
ZaltoprofenThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Zaltoprofen.Approved
ZileutonThe risk or severity of adverse effects can be increased when Zileuton is combined with Acetylsalicylic acid.Approved, Investigational, Withdrawn
ZimelidineZimelidine may increase the antiplatelet activities of Acetylsalicylic acid.Withdrawn
Zoledronic acidThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Zoledronic acid.Approved
ZomepiracThe risk or severity of adverse effects can be increased when Acetylsalicylic acid is combined with Zomepirac.Withdrawn
ZorubicinAcetylsalicylic acid may decrease the excretion rate of Zorubicin which could result in a higher serum level.Experimental
Food Interactions
  • Avoid alcohol, alcohol appears to cause a 50 to 100% increases in ASA serum levels.
  • Take with a full glass of water.
  • Take with food to reduce gastric irritation.
References
Synthesis Reference

Marino Gobetti, Guido Vandoni, “Acetylsalicylic acid thioesters, a process for their preparation and pharmaceutical compositions containing them.” U.S. Patent US4563443, issued March, 1981.

US4563443
General References
  1. Macdonald S: Aspirin use to be banned in under 16 year olds. BMJ. 2002 Nov 2;325(7371):988. [PubMed:12411346 ]
  2. Sneader W: The discovery of aspirin: a reappraisal. BMJ. 2000 Dec 23-30;321(7276):1591-4. [PubMed:11124191 ]
  3. Aukerman G, Knutson D, Miser WF: Management of the acute migraine headache. Am Fam Physician. 2002 Dec 1;66(11):2123-30. [PubMed:12484694 ]
  4. Authors unspecified: Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Lancet. 1988 Aug 13;2(8607):349-60. [PubMed:2899772 ]
  5. Dorsch MP, Lee JS, Lynch DR, Dunn SP, Rodgers JE, Schwartz T, Colby E, Montague D, Smyth SS: Aspirin resistance in patients with stable coronary artery disease with and without a history of myocardial infarction. Ann Pharmacother. 2007 May;41(5):737-41. Epub 2007 Apr 24. [PubMed:17456544 ]
External Links
ATC CodesC10BX04B01AC56C10BX05N02BA71M01BA03N02BA51C10BX06B01AC06C10BX02N02BA01A01AD05C10BX08C10BX01
AHFS Codes
  • 28:08.04.24
  • 92:02.00*
PDB EntriesNot Available
FDA labelDownload (889 KB)
MSDSDownload (18.9 KB)
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9645
Blood Brain Barrier+0.9376
Caco-2 permeable-0.6607
P-glycoprotein substrateNon-substrate0.685
P-glycoprotein inhibitor INon-inhibitor0.9118
P-glycoprotein inhibitor IINon-inhibitor0.9615
Renal organic cation transporterNon-inhibitor0.914
CYP450 2C9 substrateNon-substrate0.7518
CYP450 2D6 substrateNon-substrate0.9116
CYP450 3A4 substrateNon-substrate0.7225
CYP450 1A2 substrateNon-inhibitor0.9046
CYP450 2C9 inhibitorNon-inhibitor0.9071
CYP450 2D6 inhibitorNon-inhibitor0.9576
CYP450 2C19 inhibitorNon-inhibitor0.9445
CYP450 3A4 inhibitorNon-inhibitor0.9611
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9557
Ames testNon AMES toxic0.9326
CarcinogenicityNon-carcinogens0.8356
BiodegradationReady biodegradable0.9067
Rat acute toxicity2.6386 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9433
hERG inhibition (predictor II)Non-inhibitor0.9799
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
Manufacturers
  • Bayer healthcare llc
Packagers
Dosage forms
FormRouteStrength
TabletOral300 mg
Kit
Kit; tablet, delayed release; tablet, extended releaseOral
Capsule; capsule, extended releaseOral
Tablet, effervescentOral
Granule, effervescentOral
Tablet, delayed releaseOral600 mg
SuppositoryRectal150 mg
SuppositoryRectal650 mg
Tablet, chewableOral80 mg
Tablet, delayed releaseOral80 mg
Tablet, delayed releaseOral162 mg
Tablet, film coatedOral500 mg/1
Tablet, film coatedOral325 mg/1
Gum, chewingOral325 mg
SuppositoryRectal300 mg/1
SuppositoryRectal600 mg/1
TabletOral325 g/1
Tablet, coatedOral325 ng/1
Tablet, coatedOral81 mg/1
Tablet, extended releaseOral81 mg/1
Tablet, delayed releaseOral81 mg
CapsuleOral
Capsule, extended releaseOral
Tablet, delayed release; tablet, extended releaseOral325 mg
Tablet, delayed release; tablet, extended releaseOral500 mg
Tablet, delayed releaseOral81 mg/811
GranuleOral500 mg
Tablet, coatedOral500 mg/5001
TabletOral325 mg
TabletOral500 mg/1
Tablet, chewableOral325 mg/1
PowderOral500 mg/1
Tablet, coatedOral500 mg/1
TabletOral81 mg/1
TabletOral
PowderOral325 mg/1
PasteDental
Capsule, extended releaseOral162.5 mg/1
Tablet, delayed releaseOral325 mg/1
Tablet, delayed releaseOral325 mg/3251
Tablet, delayed releaseOral325 mg
Tablet, delayed releaseOral650 mg
Tablet, chewableOral81 mg
Tablet, delayed releaseOral500 mg
Tablet, delayed releaseOral975 mg
Tablet, chewableOral325 mg
Tablet, coatedOral
Tablet, film coatedOral
Capsule, gelatin coatedOral
TabletOral500 mg
Tablet, orally disintegratingOral81 mg/1
TabletOral325 mg/1
Tablet, chewableOral81 mg/1
Tablet, film coatedOral81 mg/1
Tablet, delayed releaseOral81 mg/1
Capsule, coatedOral
TabletTopical
PowderOral
Tablet, coatedOral325 mg/1
TabletOral325 1/1
Tablet, multilayerOral
Kit; tablet; tablet, delayed releaseOral
TabletOral81 mg
TabletOral80 mg
StripOral81 mg/1
TabletOral81 mg/81mg
TabletOral325 mg/325mg
Prices
Unit descriptionCostUnit
Entrophen 10 650 mg Enteric-Coated Tablet0.09USD tablet
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Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US5972916 No1997-07-142017-07-14Us
US6015577 No1997-01-182017-01-18Us
US8865187 No2002-03-232022-03-23Us
US9101637 No2002-03-232022-03-23Us
US9216150 No2012-09-292032-09-29Us
US9226892 No2012-09-292032-09-29Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point135 °CPhysProp
boiling point140 °CNot Available
water solubility4600 mg/L (at 25 °C)YALKOWSKY,SH & DANNENFELSER,RM (1992)
logP1.19HANSCH,C ET AL. (1995)
Caco2 permeability-5.06ADME Research, USCD
pKa3.49 (at 25 °C)MERCK INDEX (1983)
Predicted Properties
PropertyValueSource
Water Solubility1.46 mg/mLALOGPS
logP1.43ALOGPS
logP1.24ChemAxon
logS-2.1ALOGPS
pKa (Strongest Acidic)3.41ChemAxon
pKa (Strongest Basic)-7.1ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area63.6 Å2ChemAxon
Rotatable Bond Count3ChemAxon
Refractivity44.45 m3·mol-1ChemAxon
Polarizability17.1 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Download (8.27 KB)
Spectra
Spectrum TypeDescriptionSplash Key
GC-MSGC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies)splash10-014l-2960000000-ffcb8d28ab7e460b0da8View in MoNA
GC-MSGC-MS Spectrum - GC-MS (1 TMS)splash10-006w-2910000000-910e8ce2493a05870b33View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-00kr-6900000000-324f46e8def1652ed4bfView in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-000i-9000000000-cdf64eaf75083da6f355View in MoNA
LC-MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-000i-9000000000-ee75806b6fb8a38fd697View in MoNA
LC-MS/MSLC-MS/MS Spectrum - EI-B (Unknown) , Positivesplash10-00dl-9400000000-64327d3bef0063cf4fe1View in MoNA
LC-MS/MSLC-MS/MS Spectrum - CI-B (Unknown) , Positivesplash10-00di-0900000000-113943b65024522c1712View in MoNA
MSMass Spectrum (Electron Ionization)splash10-00dl-6900000000-74f8a29aa18d0c3afe98View in MoNA
1D NMR1H NMR SpectrumNot Available
1D NMR1H NMR SpectrumNot Available
1D NMR13C NMR SpectrumNot Available
2D NMR[1H,13C] 2D NMR SpectrumNot Available
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as phenol esters. These are aromatic compounds containing a benzene ring substituted by a hydroxyl group and an ester group.
KingdomOrganic compounds
Super ClassBenzenoids
ClassBenzene and substituted derivatives
Sub ClassPhenol esters
Direct ParentPhenol esters
Alternative Parents
Substituents
  • Phenol ester
  • Benzoic acid
  • Benzoic acid or derivatives
  • Benzoyl
  • Dicarboxylic acid or derivatives
  • Acetate salt
  • Carboxylic acid ester
  • Carboxylic acid
  • Carboxylic acid derivative
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External Descriptors

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Prostaglandin-endoperoxide synthase activity
Specific Function:
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the gener...
Gene Name:
PTGS1
Uniprot ID:
P23219
Molecular Weight:
68685.82 Da
References
  1. Stevenson DD, Szczeklik A: Clinical and pathologic perspectives on aspirin sensitivity and asthma. J Allergy Clin Immunol. 2006 Oct;118(4):773-86; quiz 787-8. Epub 2006 Sep 1. [PubMed:17030227 ]
  2. Flipo RM: [Are the NSAIDs able to compromising the cardio-preventive efficacy of aspirin?]. Presse Med. 2006 Sep;35(9 Spec No 1):1S53-60. [PubMed:17078596 ]
  3. Schwartz KA: Aspirin resistance: a review of diagnostic methodology, mechanisms, and clinical utility. Adv Clin Chem. 2006;42:81-110. [PubMed:17131625 ]
  4. Birnbaum Y, Ye Y, Lin Y, Freeberg SY, Huang MH, Perez-Polo JR, Uretsky BF: Aspirin augments 15-epi-lipoxin A4 production by lipopolysaccharide, but blocks the pioglitazone and atorvastatin induction of 15-epi-lipoxin A4 in the rat heart. Prostaglandins Other Lipid Mediat. 2007 Feb;83(1-2):89-98. Epub 2006 Nov 7. [PubMed:17259075 ]
  5. Guthikonda S, Lev EI, Patel R, DeLao T, Bergeron AL, Dong JF, Kleiman NS: Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin. J Thromb Haemost. 2007 Mar;5(3):490-6. [PubMed:17319904 ]
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
inhibitor
General Function:
Prostaglandin-endoperoxide synthase activity
Specific Function:
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, p...
Gene Name:
PTGS2
Uniprot ID:
P35354
Molecular Weight:
68995.625 Da
References
  1. Brzozowski T, Konturek PC, Sliwowski Z, Kwiecien S, Drozdowicz D, Pawlik M, Mach K, Konturek SJ, Pawlik WW: Interaction of nonsteroidal anti-inflammatory drugs (NSAID) with Helicobacter pylori in the stomach of humans and experimental animals. J Physiol Pharmacol. 2006 Sep;57 Suppl 3:67-79. [PubMed:17033106 ]
  2. Wang HJ, Liu XJ, Yang KX, Luo FM, Lou JY, Peng ZL: [Effects of nonsteroidal anti-inflammatory drug celecoxib on expression of cyclooxygenase-2 (COX-2) in ovarian carcinoma cell]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2006 Sep;37(5):757-60. [PubMed:17037745 ]
  3. Shen J, Gammon MD, Terry MB, Teitelbaum SL, Neugut AI, Santella RM: Genetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer risk. Breast Cancer Res. 2006;8(6):R71. [PubMed:17181859 ]
  4. Nakano M, Denda N, Matsumoto M, Kawamura M, Kawakubo Y, Hatanaka K, Hiramoto Y, Sato Y, Noshiro M, Harada Y: Interaction between cyclooxygenase (COX)-1- and COX-2-products modulates COX-2 expression in the late phase of acute inflammation. Eur J Pharmacol. 2007 Mar 22;559(2-3):210-8. Epub 2006 Dec 16. [PubMed:17258197 ]
  5. Hall MN, Campos H, Li H, Sesso HD, Stampfer MJ, Willett WC, Ma J: Blood levels of long-chain polyunsaturated fatty acids, aspirin, and the risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2007 Feb;16(2):314-21. [PubMed:17301265 ]
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
Specific Function:
Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Gene Name:
AKR1C1
Uniprot ID:
Q04828
Molecular Weight:
36788.02 Da
References
  1. Dhagat U, Carbone V, Chung RP, Matsunaga T, Endo S, Hara A, El-Kabbani O: A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase. Med Chem. 2007 Nov;3(6):546-50. [PubMed:18045204 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
activator
General Function:
Tau-protein kinase activity
Specific Function:
Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts ...
Gene Name:
PRKAA1
Uniprot ID:
Q13131
Molecular Weight:
64008.64 Da
References
  1. Din FV, Valanciute A, Houde VP, Zibrova D, Green KA, Sakamoto K, Alessi DR, Dunlop MG: Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells. Gastroenterology. 2012 Jun;142(7):1504-15.e3. doi: 10.1053/j.gastro.2012.02.050. Epub 2012 Mar 6. [PubMed:22406476 ]
  2. Hawley SA, Fullerton MD, Ross FA, Schertzer JD, Chevtzoff C, Walker KJ, Peggie MW, Zibrova D, Green KA, Mustard KJ, Kemp BE, Sakamoto K, Steinberg GR, Hardie DG: The ancient drug salicylate directly activates AMP-activated protein kinase. Science. 2012 May 18;336(6083):918-22. doi: 10.1126/science.1215327. Epub 2012 Apr 19. [PubMed:22517326 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Phosphatidylinositol phospholipase c activity
Specific Function:
Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.
Gene Name:
EDNRA
Uniprot ID:
P25101
Molecular Weight:
48721.76 Da
References
  1. Talbodec A, Berkane N, Blandin V, Breittmayer JP, Ferrari E, Frelin C, Vigne P: Aspirin and sodium salicylate inhibit endothelin ETA receptors by an allosteric type of mechanism. Mol Pharmacol. 2000 Apr;57(4):797-804. [PubMed:10727528 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Scaffold protein binding
Specific Function:
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These mo...
Gene Name:
IKBKB
Uniprot ID:
O14920
Molecular Weight:
86563.245 Da
References
  1. Yin MJ, Yamamoto Y, Gaynor RB: The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature. 1998 Nov 5;396(6706):77-80. [PubMed:9817203 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
acetylation
General Function:
Not Available
Specific Function:
Not Available
Gene Name:
TP53
Uniprot ID:
P04637
Molecular Weight:
43652.79 Da
References
  1. Alfonso LF, Srivenugopal KS, Bhat GJ: Does aspirin acetylate multiple cellular proteins? (Review). Mol Med Rep. 2009 Jul-Aug;2(4):533-7. doi: 10.3892/mmr_00000132. [PubMed:21475861 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
binding
General Function:
Unfolded protein binding
Specific Function:
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.
Gene Name:
HSPA5
Uniprot ID:
P11021
Molecular Weight:
72332.425 Da
References
  1. Deng WG, Ruan KH, Du M, Saunders MA, Wu KK: Aspirin and salicylate bind to immunoglobulin heavy chain binding protein (BiP) and inhibit its ATPase activity in human fibroblasts. FASEB J. 2001 Nov;15(13):2463-70. [PubMed:11689471 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Ribosomal protein s6 kinase activity
Specific Function:
Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apopto...
Gene Name:
RPS6KA3
Uniprot ID:
P51812
Molecular Weight:
83735.325 Da
References
  1. Stevenson MA, Zhao MJ, Asea A, Coleman CN, Calderwood SK: Salicylic acid and aspirin inhibit the activity of RSK2 kinase and repress RSK2-dependent transcription of cyclic AMP response element binding protein- and NF-kappa B-responsive genes. J Immunol. 1999 Nov 15;163(10):5608-16. [PubMed:10553090 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
General Function:
Ubiquitin protein ligase binding
Specific Function:
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Gene Name:
NFKBIA
Uniprot ID:
P25963
Molecular Weight:
35608.65 Da
References
  1. Stevenson MA, Zhao MJ, Asea A, Coleman CN, Calderwood SK: Salicylic acid and aspirin inhibit the activity of RSK2 kinase and repress RSK2-dependent transcription of cyclic AMP response element binding protein- and NF-kappa B-responsive genes. J Immunol. 1999 Nov 15;163(10):5608-16. [PubMed:10553090 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
antagonist
General Function:
Transcriptional activator activity, rna polymerase ii core promoter proximal region sequence-specific binding
Specific Function:
NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-co...
Gene Name:
NFKB2
Uniprot ID:
Q00653
Molecular Weight:
96748.355 Da
References
  1. Kopp E, Ghosh S: Inhibition of NF-kappa B by sodium salicylate and aspirin. Science. 1994 Aug 12;265(5174):956-9. [PubMed:8052854 ]

Enzymes

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inducer
General Function:
Steroid hydroxylase activity
Specific Function:
Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.
Gene Name:
CYP2C19
Uniprot ID:
P33261
Molecular Weight:
55930.545 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Steroid hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme...
Gene Name:
CYP2C8
Uniprot ID:
P10632
Molecular Weight:
55824.275 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Steroid hydroxylase activity
Specific Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenyto...
Gene Name:
CYP2C9
Uniprot ID:
P11712
Molecular Weight:
55627.365 Da
References
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]

Carriers

Kind
Protein
Organism
Human
Pharmacological action
no
Actions
other/unknown
General Function:
Toxic substance binding
Specific Function:
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
Gene Name:
ALB
Uniprot ID:
P02768
Molecular Weight:
69365.94 Da
References
  1. Sulkowska A, Bojko B, Rownicka J, Sulkowski WW: Competition of cytarabine and aspirin in binding to serum albumin in multidrug therapy. Biopolymers. 2006 Apr 15;81(6):464-72. [PubMed:16419075 ]
  2. Dundee JW, Halliday NJ, McMurray TJ: Aspirin and probenecid pretreatment influences the potency of thiopentone and the onset of action of midazolam. Eur J Anaesthesiol. 1986 May;3(3):247-51. [PubMed:3780693 ]

Transporters

Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
inhibitor
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-in...
Gene Name:
SLC22A6
Uniprot ID:
Q4U2R8
Molecular Weight:
61815.78 Da
References
  1. Apiwattanakul N, Sekine T, Chairoungdua A, Kanai Y, Nakajima N, Sophasan S, Endou H: Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Mol Pharmacol. 1999 May;55(5):847-54. [PubMed:10220563 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Xenobiotic-transporting atpase activity
Specific Function:
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Gene Name:
ABCB1
Uniprot ID:
P08183
Molecular Weight:
141477.255 Da
References
  1. Faassen F, Vogel G, Spanings H, Vromans H: Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs. Int J Pharm. 2003 Sep 16;263(1-2):113-22. [PubMed:12954186 ]
Kind
Protein
Organism
Human
Pharmacological action
unknown
Actions
substrate
General Function:
Sodium-independent organic anion transmembrane transporter activity
Specific Function:
Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulfate, allopurinol, 5-fluorouracil, paclitaxel, L-ascorbic acid, salicylate, ethotrexate, and alpha-ketoglutarate.
Gene Name:
SLC22A7
Uniprot ID:
Q9Y694
Molecular Weight:
60025.025 Da
References
  1. Sekine T, Cha SH, Tsuda M, Apiwattanakul N, Nakajima N, Kanai Y, Endou H: Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. FEBS Lett. 1998 Jun 12;429(2):179-82. [PubMed:9650585 ]
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Drug created on June 13, 2005 07:24 / Updated on December 03, 2016 03:45