Norflurane

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Norflurane
Accession Number
DB13116
Type
Small Molecule
Groups
Approved, Experimental
Description

Norflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).

Structure
Thumb
Synonyms
  • 1,1,1,2 Tetrafluoroethane
  • Tetrafluoroethane
External IDs
Dymel 134A / Forane 134A / Genetron 134A / HFA 134A / HFA-134-A / HFA-134A / HFA-134A PROPELLANT / HFC-134A / R-134A / Solkane 134A / Suva 134A
Categories
UNII
DH9E53K1Y8
CAS number
811-97-2
Weight
Average: 102.032
Monoisotopic: 102.009262716
Chemical Formula
C2H2F4
InChI Key
LVGUZGTVOIAKKC-UHFFFAOYSA-N
InChI
InChI=1S/C2H2F4/c3-1-2(4,5)6/h1H2
IUPAC Name
1,1,1,2-tetrafluoroethane
SMILES
FCC(F)(F)F

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
KEGG Drug
D05208
PubChem Compound
13129
PubChem Substance
347829239
ChemSpider
12577
ChEMBL
CHEMBL2104432
Wikipedia
1,1,1,2-Tetrafluoroethane

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4TerminatedTreatmentAbscesses1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility18.6 mg/mLALOGPS
logP1.39ALOGPS
logP1.33ChemAxon
logS-0.74ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count1ChemAxon
Refractivity12.02 m3·mol-1ChemAxon
Polarizability4.84 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as organofluorides. These are compounds containing a chemical bond between a carbon atom and a fluorine atom.
Kingdom
Organic compounds
Super Class
Organohalogen compounds
Class
Organofluorides
Sub Class
Not Available
Direct Parent
Organofluorides
Alternative Parents
Hydrofluorocarbons / Hydrocarbon derivatives / Alkyl fluorides
Substituents
Hydrofluorocarbon / Hydrocarbon derivative / Organofluoride / Alkyl halide / Alkyl fluoride / Aliphatic acyclic compound
Molecular Framework
Aliphatic acyclic compounds
External Descriptors
Not Available

Drug created on October 20, 2016 21:20 / Updated on November 02, 2018 07:34