Amenorrhea

Also known as: Amenorrheaa / Amenorrhoea / Amenorhea / Amenorrhoea NOS / Absence of menstruation / Menses lack of / Amenorrhea, unspecified

DrugDrug NameDrug Description
DB00044Lutropin alfaA form of recombinant human luteinizing hormone used to treat female infertility due to hypothalamic or pituitary insufficiency, or due to profound luteinizing hormone deficiency.
DB00603Medroxyprogesterone acetateA progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty.
DB00396ProgesteroneA hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia.
DB00094UrofollitropinA form of purified human follicle stimulating hormone used to treat infertility in females by inducing follicle development in women without primary ovarian failure.
DrugDrug NameTargetType
DB00044Lutropin alfaLutropin-choriogonadotropic hormone receptortarget
DB00603Medroxyprogesterone acetateProgesterone receptortarget
DB00603Medroxyprogesterone acetateEstrogen receptor alphatarget
DB00603Medroxyprogesterone acetateCytochrome P450 3A4enzyme
DB00603Medroxyprogesterone acetateCytochrome P450 2C8enzyme
DB00603Medroxyprogesterone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
DB00603Medroxyprogesterone acetateCytochrome P450 2C9enzyme
DB00603Medroxyprogesterone acetateCytochrome P450 3A1enzyme
DB00603Medroxyprogesterone acetateSerum albumincarrier
DB00603Medroxyprogesterone acetateP-glycoprotein 1target
DB00603Medroxyprogesterone acetateGABA-A receptor (anion channel)target
DB00603Medroxyprogesterone acetateP-glycoprotein 1transporter
DB00396ProgesteroneProgesterone receptortarget
DB00396ProgesteroneEstrogen receptor alphatarget
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB00396ProgesteroneCytochrome P450 2C19enzyme
DB00396ProgesteroneCytochrome P450 2C9enzyme
DB00396ProgesteroneCytochrome P450 3A4enzyme
DB00396ProgesteroneCytochrome P450 3A5enzyme
DB00396ProgesteroneCytochrome P450 3A7enzyme
DB00396ProgesteroneP-glycoprotein 1transporter
DB00396ProgesteroneSolute carrier family 22 member 2transporter
DB00396ProgesteroneSolute carrier family 22 member 1transporter
DB00396ProgesteroneSolute carrier family 22 member 3transporter
DB00396ProgesteroneBile salt export pumptransporter
DB00396ProgesteroneMultidrug resistance-associated protein 1transporter
DB00396ProgesteroneSodium/bile acid cotransportertransporter
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB00396ProgesteroneCytochrome P450 1A1enzyme
DB00396ProgesteroneCytochrome P450 1B1enzyme
DB00396ProgesteroneCytochrome P450 2A6enzyme
DB00396ProgesteroneCytochrome P450 2D6enzyme
DB00396ProgesteroneMineralocorticoid receptortarget
DB00396ProgesteroneKappa-type opioid receptortarget
DB00396ProgesteroneAlpha-1-acid glycoprotein 1target
DB00396ProgesteroneGlucocorticoid receptortarget
DB00396ProgesteroneAndrogen receptortarget
DB00396ProgesteroneSex hormone-binding globulintarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B1transporter
DB00396ProgesteroneATP-binding cassette sub-family G member 2transporter
DB00396ProgesteroneEstrogen receptor betatarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B3transporter
DB00094UrofollitropinFollicle-stimulating hormone receptortarget
DrugDrug NamePhaseStatusCount
DB05253Telapristone acetate1Terminated1
DB05253Telapristone acetate1 / 2Completed1
DB06680Asoprisnil2Completed1
DB00286Conjugated estrogens2Completed1
DB00644Gonadorelin2Recruiting1
DB00007Leuprolide2Completed1
DB09046Metreleptin2Unknown Status1
DB00396Progesterone2Completed1
DB00783Estradiol3Withdrawn1
DB00396Progesterone3Withdrawn1
DB06724Calcium carbonate4Not Yet Recruiting1
DB00169Cholecalciferol4Not Yet Recruiting1
DB04839Cyproterone acetate4Unknown Status1
DB00783Estradiol4Not Yet Recruiting1
DB00977Ethinylestradiol4Unknown Status1
DB00644Gonadorelin4Not Yet Recruiting1
DB00007Leuprolide4Not Yet Recruiting1
DB00331Metformin4Completed1
DB09070Tibolone4Not Yet Recruiting1
DB00331MetforminNot AvailableWithdrawn1